GREMLIN Database
YDAJ - Putative lipoprotein YdaJ
UniProt: O31486 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 362 (316)
Sequences: 131 (112)
Seq/√Len: 6.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
243_L297_A3.7280.92
102_L152_I3.2830.86
94_Y148_T3.0710.81
273_L297_A3.0070.80
264_K306_E2.9390.78
91_Q136_A2.6730.71
120_T237_I2.5180.66
334_Y348_P2.4660.64
81_L89_H2.4630.64
110_W289_E2.4510.64
239_L273_L2.3140.59
69_Y81_L2.3040.59
107_L112_I2.2790.58
243_L273_L2.2690.58
58_L61_T2.2490.57
109_T112_I2.2420.57
127_M166_F2.2170.56
214_P217_N2.2080.55
47_F52_L2.1920.55
81_L295_A2.1810.54
186_P252_G2.1730.54
58_L62_D2.1710.54
48_I292_S2.1610.54
44_A322_E2.1180.52
239_L259_L2.0950.51
236_E276_R2.0590.50
202_T219_F2.0580.50
246_A300_F2.0270.49
259_L300_F2.0190.49
48_I333_G1.9880.47
278_S285_A1.9830.47
76_L343_F1.9820.47
122_A183_Y1.9170.45
47_F332_G1.9110.45
152_I319_N1.9080.45
66_Q345_N1.8370.42
298_V315_Y1.8320.42
179_V184_V1.8290.42
136_A145_Y1.8270.42
52_L209_V1.8090.41
175_A204_Q1.7940.40
85_N273_L1.7940.40
97_L293_V1.7900.40
123_L341_H1.7640.39
54_N58_L1.7480.39
47_F345_N1.7420.39
319_N352_E1.7240.38
201_E230_E1.7210.38
301_L306_E1.7050.37
238_N241_D1.6950.37
261_D312_K1.6880.37
210_L334_Y1.6860.37
57_G171_D1.6780.36
260_A264_K1.6140.34
169_F181_L1.5950.34
185_M220_L1.5810.33
182_S241_D1.5810.33
186_P210_L1.5790.33
77_W81_L1.5780.33
213_A236_E1.5780.33
342_S346_L1.5690.33
60_K67_P1.5530.32
123_L293_V1.5410.32
141_G144_D1.5130.31
227_E230_E1.5040.31
48_I106_H1.4820.30
328_K331_Y1.4810.30
265_Q305_H1.4780.30
131_L185_M1.4700.30
243_L296_L1.4630.30
219_F341_H1.4560.29
48_I290_S1.4550.29
207_A262_W1.4530.29
164_G250_P1.4490.29
301_L310_V1.4400.29
181_L219_F1.4390.29
72_E75_G1.4210.28
145_Y277_Y1.4140.28
222_K234_D1.4110.28
214_P298_V1.4090.28
64_S170_Y1.4020.28
82_L138_A1.3980.28
171_D296_L1.3920.27
164_G309_S1.3810.27
44_A67_P1.3700.27
242_Q246_A1.3590.27
110_W241_D1.3550.26
54_N120_T1.3540.26
96_H101_F1.3490.26
82_L122_A1.3480.26
106_H263_I1.3400.26
333_G352_E1.3380.26
153_G283_E1.3380.26
275_G288_Y1.3290.26
108_V241_D1.3180.25
286_V341_H1.3010.25
181_L231_Y1.2900.25
235_S285_A1.2880.25
237_I264_K1.2810.24
251_E306_E1.2730.24
101_F219_F1.2610.24
300_F311_I1.2580.24
73_S290_S1.2510.24
79_E141_G1.2490.24
140_W334_Y1.2430.23
189_L221_P1.2350.23
55_D142_R1.2320.23
189_L199_D1.2320.23
107_L292_S1.2310.23
111_K123_L1.2300.23
97_L110_W1.2240.23
127_M209_V1.2240.23
123_L166_F1.2230.23
86_D350_L1.2230.23
220_L244_Y1.2210.23
341_H348_P1.2190.23
138_A164_G1.2190.23
52_L345_N1.2170.23
222_K241_D1.2100.23
206_N219_F1.2050.22
67_P251_E1.2030.22
266_E282_K1.1940.22
176_S331_Y1.1820.22
237_I242_Q1.1780.22
86_D89_H1.1690.22
74_L97_L1.1640.21
125_D294_Y1.1590.21
128_R294_Y1.1590.21
125_D128_R1.1590.21
137_A146_A1.1530.21
48_I305_H1.1530.21
136_A140_W1.1440.21
233_Y286_V1.1390.21
78_M266_E1.1330.21
101_F238_N1.1210.20
108_V112_I1.1180.20
145_Y351_A1.1120.20
90_F122_A1.1040.20
258_V292_S1.1030.20
93_Q275_G1.1000.20
141_G350_L1.0980.20
179_V219_F1.0930.20
275_G291_P1.0900.20
127_M346_L1.0870.20
214_P348_P1.0870.20
262_W278_S1.0860.20
74_L101_F1.0850.20
144_D228_T1.0770.19
124_I206_N1.0760.19
48_I68_S1.0760.19
42_Q212_S1.0700.19
154_T224_Y1.0620.19
220_L299_L1.0620.19
78_M205_R1.0600.19
97_L101_F1.0540.19
106_H217_N1.0530.19
52_L346_L1.0470.19
168_D183_Y1.0470.19
48_I145_Y1.0420.19
290_S342_S1.0410.19
219_F231_Y1.0320.18
182_S218_G1.0320.18
291_P318_M1.0300.18
81_L174_A1.0290.18
123_L221_P1.0280.18
286_V289_E1.0270.18
62_D353_R1.0250.18
217_N302_T1.0220.18
133_L277_Y1.0210.18
47_F346_L1.0180.18
79_E83_S1.0170.18
242_Q341_H1.0130.18
213_A335_M1.0060.18
217_N264_K1.0050.18
286_V340_T0.9980.18
188_A348_P0.9980.18
214_P315_Y0.9980.18
70_L75_G0.9880.17
181_L213_A0.9870.17
301_L309_S0.9830.17
44_A243_L0.9810.17
332_G349_L0.9720.17
75_G129_I0.9690.17
333_G345_N0.9680.17
109_T118_S0.9680.17
233_Y340_T0.9680.17
55_D258_V0.9650.17
170_Y300_F0.9650.17
91_Q230_E0.9610.17
78_M97_L0.9610.17
123_L348_P0.9600.17
78_M343_F0.9590.17
152_I352_E0.9550.17
75_G80_F0.9550.17
275_G344_D0.9490.17
85_N265_Q0.9430.16
53_M292_S0.9400.16
169_F172_S0.9400.16
211_Y263_I0.9340.16
225_S268_Q0.9330.16
241_D298_V0.9330.16
256_A300_F0.9260.16
52_L332_G0.9240.16
149_A267_F0.9240.16
345_N349_L0.9220.16
93_Q97_L0.9200.16
323_I328_K0.9190.16
179_V209_V0.9160.16
221_P315_Y0.9140.16
100_S112_I0.9050.16
224_Y333_G0.9030.16
301_L314_I0.9000.16
101_F189_L0.8990.16
151_D227_E0.8940.16
141_G230_E0.8930.15
214_P352_E0.8900.15
121_N238_N0.8860.15
72_E125_D0.8830.15
72_E128_R0.8830.15
72_E294_Y0.8830.15
185_M332_G0.8820.15
116_Q325_D0.8780.15
132_S203_E0.8760.15
241_D347_L0.8760.15
346_L349_L0.8750.15
218_G310_V0.8720.15
222_K345_N0.8690.15
62_D75_G0.8660.15
69_Y335_M0.8600.15
288_Y293_V0.8590.15
101_F121_N0.8570.15
42_Q49_Y0.8560.15
121_N286_V0.8540.15
182_S242_Q0.8540.15
137_A162_N0.8520.15
134_D150_R0.8420.15
268_Q316_D0.8410.15
137_A268_Q0.8410.15
62_D244_Y0.8370.14
220_L259_L0.8360.14
280_Y292_S0.8340.14
45_E188_A0.8320.14
77_W318_M0.8250.14
262_W302_T0.8250.14
334_Y347_L0.8230.14
113_Q292_S0.8220.14
190_A205_R0.8200.14
151_D159_Y0.8200.14
45_E303_K0.8170.14
78_M279_A0.8170.14
267_F298_V0.8120.14
78_M314_I0.8110.14
168_D180_T0.8070.14
347_L352_E0.8020.14
221_P242_Q0.8000.14
288_Y344_D0.8000.14
83_S280_Y0.7980.14
47_F349_L0.7960.14
45_E333_G0.7940.14
92_D261_D0.7910.14
78_M93_Q0.7880.14
222_K242_Q0.7880.14
287_Q312_K0.7880.14
69_Y77_W0.7810.13
315_Y352_E0.7800.13
75_G90_F0.7760.13
249_L342_S0.7750.13
171_D189_L0.7660.13
280_Y305_H0.7620.13
208_N283_E0.7600.13
52_L300_F0.7590.13
77_W140_W0.7580.13
140_W292_S0.7520.13
62_D68_S0.7470.13
58_L213_A0.7460.13
52_L172_S0.7440.13
186_P218_G0.7440.13
176_S229_K0.7430.13
309_S314_I0.7400.13
240_I244_Y0.7400.13
210_L348_P0.7400.13
126_D294_Y0.7400.13
95_Q271_G0.7380.13
332_G345_N0.7370.13
77_W312_K0.7330.13
84_K252_G0.7320.13
75_G110_W0.7310.13
87_A91_Q0.7280.13
224_Y332_G0.7260.13
108_V160_N0.7230.13
50_H261_D0.7220.13
186_P334_Y0.7200.12
95_Q220_L0.7200.12
65_D107_L0.7180.12
179_V340_T0.7180.12
101_F199_D0.7170.12
225_S228_T0.7170.12
48_I197_I0.7160.12
179_V192_L0.7160.12
181_L301_L0.7160.12
86_D110_W0.7160.12
38_A248_H0.7120.12
208_N313_A0.7060.12
108_V289_E0.7050.12
131_L187_D0.7050.12
48_I169_F0.7030.12
117_A212_S0.7010.12
270_N295_A0.6970.12
128_R183_Y0.6970.12
183_Y294_Y0.6970.12
47_F231_Y0.6970.12
125_D183_Y0.6970.12
59_I109_T0.6960.12
144_D225_S0.6870.12
219_F315_Y0.6850.12
153_G321_F0.6830.12
267_F352_E0.6820.12
124_I180_T0.6820.12
73_S133_L0.6820.12
104_S211_Y0.6810.12
81_L322_E0.6810.12
73_S243_L0.6800.12
182_S246_A0.6800.12
37_N154_T0.6780.12
92_D284_P0.6780.12
52_L140_W0.6770.12
291_P333_G0.6770.12
47_F66_Q0.6720.12
62_D107_L0.6700.12
146_A323_I0.6680.12
250_P304_Q0.6660.12
295_A301_L0.6650.12
263_I297_A0.6630.12
144_D211_Y0.6630.12
121_N347_L0.6630.12
333_G349_L0.6600.12
75_G128_R0.6580.12
75_G125_D0.6580.12
75_G294_Y0.6580.12
77_W193_K0.6580.12
240_I288_Y0.6560.11
61_T110_W0.6530.11
233_Y315_Y0.6520.11
68_S292_S0.6500.11
275_G286_V0.6500.11
82_L296_L0.6490.11
195_N240_I0.6450.11
38_A230_E0.6450.11
291_P348_P0.6440.11
266_E270_N0.6420.11
177_K227_E0.6410.11
177_K312_K0.6370.11
42_Q326_P0.6310.11
132_S204_Q0.6310.11
107_L124_I0.6280.11
105_N147_Q0.6270.11
163_N264_K0.6270.11
58_L69_Y0.6260.11
95_Q257_S0.6260.11
115_G143_S0.6240.11
121_N275_G0.6230.11
99_D261_D0.6220.11
170_Y219_F0.6210.11
127_M224_Y0.6190.11
200_E229_K0.6180.11
132_S250_P0.6170.11
79_E236_E0.6150.11
196_G240_I0.6140.11
179_V263_I0.6120.11
244_Y267_F0.6120.11
85_N149_A0.6120.11
273_L299_L0.6120.11
117_A176_S0.6090.11
249_L256_A0.6080.11
118_S262_W0.6070.11
214_P341_H0.6070.11
82_L273_L0.6060.11
162_N229_K0.6020.11
156_L249_L0.5990.11
41_L328_K0.5980.11
70_L128_R0.5960.11
70_L294_Y0.5960.11
70_L125_D0.5960.11
141_G201_E0.5960.11
242_Q288_Y0.5950.11
295_A342_S0.5910.11
82_L289_E0.5890.11
160_N169_F0.5880.11
182_S240_I0.5880.11
92_D280_Y0.5850.10
124_I220_L0.5850.10
178_D224_Y0.5840.10
249_L273_L0.5840.10
107_L118_S0.5840.10
45_E84_K0.5810.10
39_S321_F0.5800.10
243_L251_E0.5790.10
182_S300_F0.5770.10
289_E344_D0.5770.10
321_F344_D0.5740.10
149_A303_K0.5730.10
59_I176_S0.5720.10
61_T140_W0.5710.10
286_V344_D0.5690.10
156_L262_W0.5680.10
123_L179_V0.5640.10
158_T175_A0.5620.10
86_D210_L0.5610.10
139_K323_I0.5590.10
121_N241_D0.5580.10
166_F220_L0.5580.10
58_L97_L0.5570.10
54_N325_D0.5560.10
112_I124_I0.5560.10
171_D290_S0.5550.10
237_I266_E0.5540.10
214_P242_Q0.5520.10
241_D245_A0.5520.10
118_S124_I0.5510.10
107_L317_R0.5490.10
91_Q232_T0.5480.10
231_Y345_N0.5470.10
92_D163_N0.5470.10
77_W248_H0.5460.10
287_Q320_D0.5460.10
144_D150_R0.5440.10
106_H344_D0.5440.10
98_T225_S0.5440.10
72_E90_F0.5420.10
242_Q300_F0.5400.10
66_Q120_T0.5390.10
129_I326_P0.5390.10
293_V344_D0.5390.10
120_T266_E0.5390.10
175_A331_Y0.5380.10
97_L344_D0.5370.10
211_Y353_R0.5370.10
238_N296_L0.5360.10
61_T222_K0.5360.10
111_K121_N0.5360.10
132_S181_L0.5350.10
71_S180_T0.5340.10
166_F251_E0.5340.10
180_T310_V0.5330.10
102_L110_W0.5320.10
185_M224_Y0.5310.10
159_Y200_E0.5310.10
154_T266_E0.5310.10
241_D267_F0.5290.10
184_V325_D0.5280.10
47_F61_T0.5270.10
203_E316_D0.5260.10
177_K250_P0.5250.10
239_L246_A0.5250.10
68_S101_F0.5230.10
249_L278_S0.5230.10
142_R338_T0.5220.10
182_S347_L0.5220.10
130_M149_A0.5200.10
77_W345_N0.5200.10
275_G289_E0.5190.10
59_I224_Y0.5170.10
261_D320_D0.5160.10
288_Y311_I0.5150.10
219_F243_L0.5150.10
88_P140_W0.5140.10
162_N258_V0.5130.10
67_P342_S0.5120.10
44_A220_L0.5100.09
48_I275_G0.5100.09
225_S235_S0.5090.09
348_P352_E0.5040.09
86_D334_Y0.5010.09
241_D266_E0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3renA 1 0.895 100 0.503 Contact Map
1kwfA 1 0.9006 100 0.722 Contact Map
1v5dA 1 0.8978 100 0.75 Contact Map
1wzzA 1 0.8232 100 0.751 Contact Map
1h12A 1 0.9061 100 0.752 Contact Map
5cd2A 1 0.8315 100 0.752 Contact Map
4q2bA 4 0.8315 100 0.763 Contact Map
1wu4A 1 0.9116 100 0.771 Contact Map
3qxfA 1 0.8232 100 0.771 Contact Map
4v1sA 1 0.7265 96.7 0.943 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0101 seconds.