YCZH - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YCZH - Uncharacterized protein YczH

UniProt:	O31482	Sequences: MFPKPLVILAHEIYGVNSHMKKMGRLIKMAGYDVLTPNLLGEDEVYTLKEEKTAYEQFTKHERLKTGETIIQNVIRQNAGRHIFVIGFSVGATIAWKCSSMPEVSGSVCYYGSRIRDSLHHMPACPVLLFFPNYEPSFDVALLIKKLREKQHTHLEIYQFDALHGFANPDSVYFNRALFFKTLSIIKNGAESRLRTVSSSFF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	202 (190)
Sequences:	5658 (3854)
Seq/√Len:	279.6

ECOLI - YGHX DLHH
BACSU - YCZH
SULSO - DLHH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
176_R	180_F	3.316	1.00
95_A	107_S	2.774	1.00
85_V	95_A	2.691	1.00
24_G	36_T	2.357	1.00
160_F	185_I	2.346	1.00
133_N	161_D	2.332	1.00
120_H	123_P	2.280	1.00
144_I	148_R	2.234	1.00
9_L	34_V	2.118	1.00
99_S	107_S	2.109	1.00
184_S	188_N	2.083	1.00
82_H	105_S	2.073	1.00
30_A	187_K	2.007	1.00
181_K	185_I	2.002	1.00
84_F	190_A	1.963	1.00
189_G	193_R	1.962	1.00
145_K	149_E	1.944	1.00
106_G	189_G	1.878	1.00
160_F	181_K	1.877	1.00
72_Q	76_R	1.862	1.00
175_N	178_L	1.850	1.00
110_Y	186_I	1.741	1.00
48_L	51_E	1.701	1.00
139_D	142_L	1.694	1.00
108_V	186_I	1.693	1.00
70_I	74_V	1.671	1.00
126_P	192_S	1.641	1.00
75_I	83_I	1.634	1.00
51_E	54_A	1.627	1.00
54_A	57_Q	1.625	1.00
48_L	52_K	1.588	1.00
163_L	175_N	1.583	1.00
57_Q	61_H	1.558	1.00
109_C	112_G	1.530	1.00
119_L	123_P	1.523	1.00
134_Y	163_L	1.521	1.00
106_G	193_R	1.518	1.00
133_N	162_A	1.489	1.00
9_L	24_G	1.470	1.00
71_I	98_C	1.464	1.00
56_E	60_K	1.461	1.00
66_T	70_I	1.459	1.00
92_A	109_C	1.439	1.00
156_E	185_I	1.409	1.00
49_K	53_T	1.408	1.00
32_Y	191_E	1.404	1.00
43_D	61_H	1.397	1.00
19_H	23_M	1.396	1.00
85_V	104_V	1.386	1.00
16_V	21_K	1.379	1.00
109_C	129_L	1.373	1.00
63_R	66_T	1.367	1.00
19_H	167_A	1.366	1.00
49_K	52_K	1.361	1.00
110_Y	167_A	1.349	1.00
166_F	182_T	1.324	1.00
148_R	155_L	1.322	1.00
27_I	183_L	1.306	1.00
50_E	53_T	1.303	1.00
108_V	128_L	1.301	1.00
20_M	36_T	1.289	1.00
86_I	186_I	1.284	1.00
107_S	125_C	1.281	1.00
158_Y	181_K	1.272	1.00
144_I	157_I	1.265	1.00
30_A	191_E	1.257	1.00
143_L	147_L	1.256	1.00
156_E	192_S	1.247	1.00
180_F	184_S	1.239	1.00
158_Y	185_I	1.234	1.00
147_L	155_L	1.214	1.00
32_Y	187_K	1.213	1.00
126_P	193_R	1.210	1.00
41_G	70_I	1.206	1.00
55_Y	58_F	1.194	1.00
118_S	121_H	1.188	1.00
7_V	34_V	1.187	1.00
84_F	194_L	1.182	1.00
108_V	130_F	1.164	1.00
146_K	149_E	1.161	1.00
62_E	67_G	1.161	1.00
128_L	158_Y	1.158	1.00
130_F	181_K	1.156	1.00
130_F	160_F	1.155	1.00
7_V	27_I	1.134	1.00
6_L	78_N	1.133	1.00
96_W	127_V	1.130	1.00
84_F	106_G	1.105	1.00
79_A	82_H	1.099	1.00
42_E	70_I	1.099	1.00
27_I	186_I	1.088	1.00
21_K	25_R	1.082	1.00
108_V	190_A	1.081	1.00
174_F	179_F	1.078	1.00
26_L	183_L	1.077	1.00
134_Y	162_A	1.064	1.00
35_L	74_V	1.054	1.00
133_N	159_Q	1.045	1.00
19_H	169_P	1.044	1.00
53_T	57_Q	1.032	1.00
126_P	154_H	1.029	1.00
10_A	85_V	1.026	1.00
86_I	190_A	1.020	1.00
23_M	167_A	1.015	1.00
22_K	25_R	1.003	1.00
150_K	153_T	1.001	1.00
57_Q	60_K	0.994	1.00
66_T	69_T	0.994	1.00
10_A	94_I	0.989	1.00
93_T	113_S	0.988	1.00
5_P	32_Y	0.973	1.00
130_F	185_I	0.969	1.00
185_I	188_N	0.967	1.00
128_L	189_G	0.960	1.00
26_L	30_A	0.960	1.00
177_A	181_K	0.957	1.00
76_R	103_E	0.949	1.00
68_E	97_K	0.949	1.00
12_E	17_N	0.939	1.00
12_E	168_N	0.938	1.00
130_F	158_Y	0.936	1.00
23_M	26_L	0.935	1.00
129_L	157_I	0.934	1.00
27_I	86_I	0.929	1.00
187_K	191_E	0.928	1.00
107_S	127_V	0.926	1.00
6_L	33_D	0.925	1.00
104_V	107_S	0.919	1.00
55_Y	59_T	0.918	1.00
145_K	148_R	0.914	1.00
47_T	51_E	0.910	1.00
113_S	137_S	0.909	1.00
93_T	97_K	0.909	1.00
184_S	191_E	0.908	1.00
85_V	98_C	0.907	1.00
146_K	150_K	0.899	1.00
23_M	88_F	0.893	1.00
131_F	157_I	0.890	1.00
18_S	22_K	0.889	1.00
162_A	175_N	0.886	1.00
118_S	123_P	0.884	1.00
16_V	36_T	0.884	1.00
4_K	81_R	0.883	1.00
119_L	122_M	0.876	1.00
6_L	79_A	0.875	1.00
10_A	71_I	0.869	1.00
179_F	182_T	0.867	1.00
33_D	78_N	0.865	1.00
18_S	21_K	0.865	1.00
24_G	34_V	0.862	1.00
113_S	138_F	0.860	1.00
188_N	192_S	0.859	1.00
50_E	54_A	0.856	1.00
48_L	54_A	0.855	1.00
70_I	73_N	0.854	1.00
11_H	36_T	0.849	1.00
10_A	39_L	0.849	1.00
11_H	37_P	0.847	1.00
168_N	171_S	0.846	1.00
12_E	20_M	0.841	1.00
128_L	156_E	0.835	1.00
25_R	29_M	0.831	1.00
22_K	170_D	0.829	1.00
111_Y	167_A	0.827	1.00
56_E	59_T	0.819	0.99
26_L	169_P	0.807	0.99
52_K	56_E	0.785	0.99
9_L	20_M	0.783	0.99
46_Y	49_K	0.781	0.99
126_P	189_G	0.779	0.99
43_D	58_F	0.776	0.99
73_N	76_R	0.775	0.99
7_V	84_F	0.766	0.99
167_A	182_T	0.765	0.99
69_T	72_Q	0.765	0.99
136_P	163_L	0.763	0.99
68_E	72_Q	0.758	0.99
22_K	169_P	0.758	0.99
144_I	159_Q	0.755	0.99
19_H	22_K	0.750	0.99
181_K	184_S	0.749	0.99
144_I	155_L	0.744	0.99
128_L	185_I	0.740	0.99
17_N	20_M	0.738	0.99
65_K	69_T	0.737	0.99
132_P	163_L	0.736	0.99
77_Q	81_R	0.735	0.99
4_K	33_D	0.725	0.99
143_L	146_K	0.721	0.99
130_F	186_I	0.719	0.99
89_S	111_Y	0.719	0.99
71_I	75_I	0.718	0.99
9_L	23_M	0.718	0.99
42_E	45_V	0.712	0.99
154_H	193_R	0.711	0.99
39_L	90_V	0.709	0.99
72_Q	101_M	0.707	0.98
89_S	164_H	0.701	0.98
26_L	180_F	0.691	0.98
69_T	73_N	0.684	0.98
186_I	190_A	0.683	0.98
165_G	168_N	0.673	0.98
8_I	104_V	0.671	0.98
12_E	19_H	0.668	0.98
112_G	131_F	0.666	0.98
108_V	189_G	0.666	0.98
131_F	159_Q	0.660	0.98
13_I	40_L	0.650	0.97
102_P	124_A	0.649	0.97
18_S	170_D	0.649	0.97
43_D	62_E	0.646	0.97
88_F	179_F	0.644	0.97
26_L	179_F	0.644	0.97
7_V	190_A	0.643	0.97
178_L	182_T	0.643	0.97
105_S	126_P	0.643	0.97
6_L	74_V	0.643	0.97
46_Y	52_K	0.639	0.97
30_A	183_L	0.639	0.97
11_H	16_V	0.638	0.97
53_T	56_E	0.635	0.97
26_L	29_M	0.635	0.97
71_I	94_I	0.627	0.97
47_T	52_K	0.623	0.97
132_P	135_E	0.615	0.96
134_Y	175_N	0.613	0.96
118_S	122_M	0.608	0.96
183_L	187_K	0.607	0.96
86_I	110_Y	0.607	0.96
62_E	90_V	0.604	0.96
72_Q	75_I	0.601	0.96
117_D	120_H	0.600	0.96
71_I	74_V	0.594	0.96
95_A	109_C	0.593	0.96
34_V	37_P	0.592	0.96
96_W	115_I	0.587	0.95
23_M	27_I	0.586	0.95
98_C	102_P	0.580	0.95
85_V	107_S	0.580	0.95
67_G	94_I	0.579	0.95
13_I	89_S	0.579	0.95
48_L	55_Y	0.575	0.95
64_L	93_T	0.575	0.95
93_T	114_R	0.573	0.95
130_F	182_T	0.573	0.95
6_L	35_L	0.573	0.95
54_A	58_F	0.567	0.94
138_F	143_L	0.567	0.94
88_F	168_N	0.566	0.94
49_K	54_A	0.565	0.94
77_Q	80_G	0.563	0.94
141_A	145_K	0.562	0.94
9_L	36_T	0.562	0.94
70_I	75_I	0.561	0.94
114_R	117_D	0.559	0.94
188_N	191_E	0.558	0.94
72_Q	103_E	0.555	0.94
135_E	164_H	0.554	0.94
90_V	94_I	0.553	0.94
182_T	186_I	0.549	0.93
38_N	41_G	0.548	0.93
40_L	90_V	0.540	0.93
48_L	53_T	0.538	0.93
165_G	171_S	0.536	0.93
9_L	86_I	0.535	0.93
6_L	83_I	0.532	0.92
63_R	70_I	0.528	0.92
89_S	165_G	0.525	0.92
7_V	32_Y	0.521	0.92
87_G	91_G	0.521	0.92
8_I	37_P	0.521	0.92
64_L	67_G	0.520	0.91
33_D	79_A	0.516	0.91
40_L	44_E	0.514	0.91
11_H	39_L	0.513	0.91
39_L	94_I	0.513	0.91
46_Y	51_E	0.512	0.91
88_F	182_T	0.512	0.91
86_I	95_A	0.510	0.91
99_S	125_C	0.510	0.91
75_I	104_V	0.508	0.90
55_Y	62_E	0.502	0.90
10_A	90_V	0.501	0.90
88_F	167_A	0.501	0.90
93_T	115_I	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1zi8A	1	0.9653	99.9	0.499	Contact Map
4zv9A	1	0.9455	99.9	0.502	Contact Map
3f67A	1	0.9505	99.9	0.523	Contact Map
3d59A	2	0.995	99.8	0.593	Contact Map
2fx5A	1	0.9208	99.8	0.597	Contact Map
4cg1A	1	0.9158	99.8	0.599	Contact Map
1xfdA	2	0.9208	99.8	0.602	Contact Map
4hxfB	4	0.9653	99.8	0.604	Contact Map
3o4hA	2	0.9208	99.8	0.604	Contact Map
2ecfA	2	0.9158	99.8	0.605	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0066 seconds.