GREMLIN Database
YBFQ - UPF0176 protein YbfQ
UniProt: O31457 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 322 (291)
Sequences: 1626 (912)
Seq/√Len: 53.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
146_R222_D5.4301.00
116_K204_D5.0641.00
164_E195_Q4.4501.00
50_V60_Y4.4241.00
142_L233_S3.8711.00
144_H178_Y3.1631.00
118_A213_D3.0621.00
30_C88_I2.8531.00
125_Q220_L2.8421.00
18_D21_A2.7331.00
19_P92_H2.7251.00
161_E165_E2.7241.00
12_K72_D2.6991.00
114_H202_Q2.6211.00
235_P240_E2.5591.00
34_G56_Q2.5011.00
267_K288_R2.4971.00
6_R54_V2.3801.00
27_L31_K2.3601.00
10_Y39_I2.3471.00
272_T275_N2.3341.00
74_V204_D2.2801.00
10_Y48_G2.2561.00
191_W195_Q2.2541.00
54_V77_I2.2151.00
261_A273_P2.2021.00
54_V58_E2.1841.00
164_E191_W2.1241.00
208_V225_C2.0831.00
35_L60_Y2.0691.00
58_E62_E2.0641.00
116_K119_E2.0181.00
209_T213_D2.0071.00
51_S84_A1.9971.00
29_F33_L1.9861.00
254_C259_N1.9811.00
279_Y284_S1.9671.00
250_T275_N1.9171.00
283_C287_C1.9111.00
28_A32_E1.9080.99
174_K199_D1.8840.99
6_R58_E1.8620.99
146_R220_L1.8580.99
115_L119_E1.8420.99
65_K72_D1.8250.99
250_T272_T1.8200.99
120_F203_L1.8120.99
230_E248_Y1.7610.99
141_D274_E1.7590.99
53_T56_Q1.7230.99
167_K171_E1.7030.99
291_P295_Y1.6980.99
137_D154_E1.6970.99
24_E28_A1.6880.99
106_D109_E1.6800.99
224_Q243_I1.6780.99
289_T292_R1.6590.99
245_G259_N1.6570.99
263_P276_E1.6240.98
35_L50_V1.6220.98
257_Y270_I1.5870.98
61_M75_F1.5870.98
110_T193_V1.5570.98
141_D150_R1.5160.97
126_D129_T1.4420.96
130_I175_I1.4340.96
295_Y299_H1.4320.96
61_M77_I1.4290.96
247_D250_T1.4100.96
252_E278_K1.4060.96
26_H60_Y1.4050.96
35_L88_I1.3850.96
27_L88_I1.3760.95
120_F176_L1.3740.95
167_K192_L1.3700.95
209_T212_K1.3600.95
285_H288_R1.3570.95
33_L56_Q1.3550.95
23_R92_H1.3520.95
247_D275_N1.3460.95
8_L57_T1.3450.95
216_V237_N1.3390.95
175_I197_F1.3280.94
291_P294_L1.3280.94
124_M176_L1.3190.94
19_P43_S1.3190.94
134_A159_L1.3180.94
294_L298_E1.3070.94
86_K230_E1.2940.94
29_F63_T1.2910.93
74_V209_T1.2900.93
169_M172_G1.2850.93
247_D272_T1.2830.93
129_T174_K1.2820.93
121_Y219_K1.2770.93
285_H289_T1.2700.93
119_E122_E1.2660.93
153_I159_L1.2380.92
33_L59_K1.2260.92
280_M283_C1.2160.91
122_E126_D1.2050.91
113_Q193_V1.2010.91
224_Q242_V1.1990.91
140_Y150_R1.1960.91
65_K73_M1.1870.90
258_V273_P1.1630.89
35_L57_T1.1620.89
166_H169_M1.1560.89
190_G193_V1.1510.89
44_E187_K1.1500.89
6_R79_E1.1480.89
101_L104_D1.1450.89
167_K170_L1.1410.88
189_S202_Q1.1410.88
111_T202_Q1.1020.87
252_E274_E1.1020.87
249_F271_C1.0970.86
65_K71_A1.0820.86
155_A158_E1.0810.86
123_K201_A1.0810.86
115_L123_K1.0780.85
193_V198_E1.0700.85
51_S83_H1.0520.84
6_R77_I1.0520.84
226_Y268_K1.0510.84
7_V80_A1.0470.84
172_G198_E1.0460.84
20_E43_S1.0410.83
243_I255_E1.0390.83
188_F192_L1.0370.83
99_L156_F1.0370.83
97_V157_R1.0350.83
16_I70_F1.0120.81
235_P241_H1.0030.81
239_V242_V0.9970.81
16_I22_F0.9970.81
124_M131_V0.9900.80
258_V281_R0.9890.80
31_K88_I0.9880.80
132_I163_I0.9820.79
18_D69_R0.9810.79
279_Y287_C0.9720.79
29_F32_E0.9570.78
31_K34_G0.9570.78
121_Y220_L0.9470.77
163_I197_F0.9410.77
114_H204_D0.9400.76
63_T66_A0.9380.76
65_K75_F0.9340.76
122_E125_Q0.9240.75
100_R157_R0.9230.75
15_P43_S0.9150.74
263_P273_P0.9140.74
29_F56_Q0.9090.74
24_E31_K0.9090.74
245_G270_I0.9060.74
23_R41_V0.9060.74
281_R298_E0.9030.73
271_C276_E0.8990.73
9_L49_T0.8990.73
21_A25_Q0.8980.73
245_G254_C0.8960.73
61_M73_M0.8910.72
67_D70_F0.8900.72
41_V92_H0.8820.72
30_C60_Y0.8790.71
219_K239_V0.8780.71
294_L297_K0.8770.71
29_F35_L0.8750.71
120_F131_V0.8720.71
16_I19_P0.8700.71
7_V49_T0.8700.71
168_D171_E0.8680.70
112_G200_V0.8630.70
214_P219_K0.8600.70
102_E110_T0.8550.69
8_L75_F0.8540.69
30_C39_I0.8510.69
78_D212_K0.8490.69
130_I172_G0.8470.69
208_V212_K0.8410.68
136_N184_R0.8410.68
279_Y288_R0.8370.68
86_K251_G0.8350.68
284_S287_C0.8320.67
120_F202_Q0.8240.66
244_V255_E0.8240.66
224_Q255_E0.8190.66
235_P255_E0.8160.66
14_V69_R0.8150.66
241_H255_E0.8130.65
167_K172_G0.8110.65
96_L100_R0.8090.65
167_K197_F0.8090.65
14_V70_F0.8080.65
177_T226_Y0.8020.64
292_R296_V0.8010.64
61_M65_K0.8000.64
123_K174_K0.7910.63
40_L49_T0.7880.63
99_L105_V0.7800.62
44_E96_L0.7800.62
260_C287_C0.7790.62
204_D233_S0.7780.62
151_P162_W0.7760.62
256_R259_N0.7730.61
126_D174_K0.7700.61
156_F227_V0.7700.61
264_S290_N0.7650.61
218_G240_E0.7620.60
49_T95_E0.7620.60
121_Y214_P0.7610.60
233_S242_V0.7610.60
121_Y125_Q0.7590.60
19_P25_Q0.7570.60
101_L105_V0.7550.60
107_P111_T0.7550.60
142_L232_I0.7510.59
70_F197_F0.7510.59
16_I41_V0.7490.59
162_W167_K0.7480.59
34_G83_H0.7460.59
54_V79_E0.7450.59
28_A31_K0.7440.59
50_V88_I0.7430.58
217_Q239_V0.7400.58
168_D172_G0.7360.58
119_E278_K0.7330.57
29_F59_K0.7320.57
74_V116_K0.7320.57
96_L227_V0.7290.57
49_T97_V0.7290.57
268_K295_Y0.7270.57
186_E202_Q0.7240.56
13_Y120_F0.7240.56
28_A63_T0.7180.56
76_K209_T0.7180.56
110_T194_K0.7150.56
263_P277_Y0.7130.55
6_R53_T0.7130.55
8_L50_V0.7120.55
27_L34_G0.7110.55
16_I67_D0.7080.55
140_Y144_H0.7050.54
112_G193_V0.7040.54
13_Y225_C0.7030.54
123_K176_L0.7030.54
59_K62_E0.7010.54
150_R154_E0.6980.54
24_E27_L0.6960.54
281_R288_R0.6960.54
233_S294_L0.6960.54
163_I166_H0.6950.53
35_L52_G0.6930.53
177_T189_S0.6910.53
282_S287_C0.6890.53
169_M197_F0.6860.52
43_S92_H0.6840.52
50_V56_Q0.6840.52
19_P41_V0.6840.52
151_P221_W0.6820.52
248_Y268_K0.6820.52
113_Q119_E0.6800.52
132_I151_P0.6800.52
127_P132_I0.6780.52
85_F183_V0.6780.52
217_Q237_N0.6770.52
86_K91_R0.6760.51
154_E158_E0.6760.51
237_N240_E0.6730.51
21_A31_K0.6730.51
279_Y283_C0.6710.51
22_F41_V0.6700.51
93_K157_R0.6680.51
23_R31_K0.6680.51
251_G297_K0.6640.50
165_E170_L0.6640.50
134_A188_F0.6630.50
249_F269_M0.6610.50
56_Q59_K0.6600.50
246_K268_K0.6600.50
8_L147_G0.6560.49
112_G190_G0.6540.49
32_E258_V0.6510.49
9_L76_K0.6500.49
7_V84_A0.6500.49
259_N262_N0.6470.48
152_D158_E0.6470.48
252_E273_P0.6470.48
96_L163_I0.6460.48
119_E152_D0.6440.48
295_Y298_E0.6440.48
142_L246_K0.6430.48
134_A192_L0.6430.48
208_V224_Q0.6430.48
131_V220_L0.6410.48
13_Y243_I0.6400.48
132_I167_K0.6400.48
192_L195_Q0.6390.47
12_K75_F0.6350.47
5_Y80_A0.6350.47
31_K56_Q0.6330.47
166_H172_G0.6320.47
137_D150_R0.6310.47
94_K198_E0.6290.46
163_I167_K0.6280.46
56_Q60_Y0.6260.46
112_G189_S0.6260.46
98_T233_S0.6220.46
211_G236_V0.6210.46
5_Y53_T0.6200.45
245_G256_R0.6180.45
128_N173_K0.6170.45
293_N296_V0.6130.45
267_K271_C0.6130.45
42_S94_K0.6130.45
273_P277_Y0.6120.45
237_N241_H0.6110.45
30_C46_I0.6100.44
148_A196_G0.6090.44
166_H170_L0.6080.44
68_P71_A0.6070.44
10_Y251_G0.6060.44
225_C234_V0.6060.44
9_L48_G0.6040.44
9_L13_Y0.6030.44
59_K105_V0.6010.44
80_A86_K0.5990.43
39_I48_G0.5980.43
121_Y176_L0.5980.43
30_C52_G0.5960.43
129_T132_I0.5960.43
257_Y260_C0.5930.43
222_D242_V0.5920.43
118_A217_Q0.5910.42
95_E159_L0.5900.42
277_Y284_S0.5880.42
23_R27_L0.5870.42
30_C35_L0.5850.42
147_G221_W0.5850.42
114_H120_F0.5840.42
256_R273_P0.5830.42
104_D108_N0.5810.41
249_F278_K0.5800.41
42_S96_L0.5780.41
131_V203_L0.5780.41
141_D155_A0.5780.41
114_H189_S0.5770.41
48_G159_L0.5730.41
132_I189_S0.5720.41
111_T190_G0.5710.40
130_I173_K0.5690.40
26_H35_L0.5680.40
72_D216_V0.5670.40
34_G161_E0.5660.40
142_L255_E0.5660.40
117_P209_T0.5630.40
14_V40_L0.5630.40
13_Y159_L0.5620.39
138_Y156_F0.5610.39
18_D67_D0.5610.39
17_E278_K0.5600.39
246_K289_T0.5570.39
87_K157_R0.5540.39
121_Y242_V0.5530.39
14_V117_P0.5530.39
27_L33_L0.5500.38
260_C283_C0.5500.38
118_A193_V0.5500.38
256_R260_C0.5490.38
28_A55_E0.5490.38
72_D147_G0.5490.38
216_V222_D0.5480.38
41_V69_R0.5480.38
22_F63_T0.5460.38
105_V194_K0.5450.38
48_G97_V0.5450.38
128_N174_K0.5450.38
226_Y246_K0.5440.38
111_T114_H0.5430.38
269_M272_T0.5430.38
33_L60_Y0.5410.37
29_F60_Y0.5390.37
287_C294_L0.5390.37
167_K224_Q0.5380.37
52_G57_T0.5360.37
232_I268_K0.5360.37
84_A187_K0.5350.37
189_S193_V0.5350.37
128_N172_G0.5340.37
41_V54_V0.5340.37
166_H173_K0.5310.36
144_H244_V0.5310.36
76_K159_L0.5310.36
14_V67_D0.5310.36
159_L250_T0.5300.36
218_G243_I0.5300.36
183_V257_Y0.5290.36
71_A81_E0.5280.36
13_Y101_L0.5270.36
126_D168_D0.5270.36
196_G200_V0.5270.36
81_E241_H0.5260.36
94_K101_L0.5250.36
274_E286_E0.5240.36
278_K284_S0.5220.36
13_Y208_V0.5200.35
76_K212_K0.5190.35
119_E273_P0.5190.35
137_D193_V0.5160.35
109_E194_K0.5160.35
111_T193_V0.5140.35
148_A155_A0.5120.35
107_P134_A0.5120.35
91_R162_W0.5120.35
36_L40_L0.5110.34
163_I170_L0.5110.34
203_L227_V0.5090.34
37_G45_G0.5080.34
88_I192_L0.5080.34
153_I163_I0.5070.34
96_L187_K0.5060.34
76_K95_E0.5040.34
10_Y35_L0.5030.34
40_L93_K0.5020.34
10_Y60_Y0.5020.34
243_I246_K0.5020.34
258_V274_E0.5020.34
99_L134_A0.5020.34
105_V190_G0.5010.34
158_E280_M0.5010.34
78_D82_G0.5010.34
171_E222_D0.5010.34
81_E94_K0.5000.33
28_A87_K0.5000.33
162_W169_M0.5000.33
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4f67A 1 0.7919 100 0.487 Contact Map
1gmxA 1 0.3354 99.7 0.853 Contact Map
2fsxA 1 0.3634 99.6 0.858 Contact Map
1qb0A 1 0.4876 99.6 0.86 Contact Map
1veeA 1 0.3851 99.6 0.861 Contact Map
3g5jA 1 0.3137 99.6 0.861 Contact Map
3icsA 2 0.6398 99.6 0.861 Contact Map
3fojA 1 0.3075 99.6 0.862 Contact Map
3d1pA 1 0.3447 99.6 0.863 Contact Map
1qxnA 2 0.413 99.6 0.863 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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