GREMLIN Database
YBDG - Uncharacterized protein YbdG
UniProt: O31431 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 325 (261)
Sequences: 49247 (39683)
Seq/√Len: 2456.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
59_Q94_K5.1001.00
136_I160_A4.4051.00
101_A121_Q4.1611.00
85_L314_Y3.2431.00
309_Q312_Q2.9231.00
123_R150_W2.8821.00
136_I159_K2.7081.00
92_E318_M2.6161.00
165_D269_D2.5221.00
134_P159_K2.5041.00
54_K107_E2.4851.00
262_L320_F2.4251.00
164_M313_I2.3811.00
58_Y77_A2.3351.00
297_K316_L2.3211.00
299_L316_L2.3101.00
126_L135_Y2.2581.00
150_W154_Y2.1971.00
123_R157_E2.1671.00
123_R127_M2.1301.00
49_D54_K2.1291.00
123_R154_Y2.1121.00
127_M157_E2.1101.00
144_G166_I2.0911.00
56_N105_Y2.0581.00
137_L147_A1.9981.00
120_E153_K1.9471.00
57_V125_A1.9281.00
301_G309_Q1.8751.00
59_Q96_A1.8421.00
288_A294_A1.8361.00
47_V54_K1.8291.00
149_Y153_K1.8151.00
136_I321_M1.8121.00
88_K314_Y1.7761.00
56_N77_A1.7611.00
60_E97_V1.7531.00
136_I162_I1.7351.00
71_S103_Y1.7081.00
151_A161_I1.7041.00
147_A161_I1.6771.00
316_L319_E1.6761.00
66_T131_N1.6581.00
98_V122_T1.6561.00
93_N136_I1.6481.00
315_K319_E1.6131.00
66_T96_A1.6041.00
116_D153_K1.5991.00
267_V298_E1.5941.00
71_S100_R1.5931.00
100_R146_E1.5551.00
61_G94_K1.5521.00
114_D117_T1.5381.00
261_V291_F1.5141.00
66_T94_K1.5081.00
51_D124_K1.5031.00
286_A290_Q1.4841.00
274_S298_E1.4661.00
122_T150_W1.4591.00
70_M122_T1.4541.00
162_I317_S1.4411.00
150_W158_I1.4351.00
70_M100_R1.4301.00
154_Y157_E1.4241.00
262_L297_K1.4051.00
75_I81_E1.4021.00
119_L149_Y1.4021.00
76_A80_Y1.3931.00
70_M147_A1.3931.00
46_T57_V1.3851.00
56_N99_D1.3521.00
60_E86_Y1.3371.00
55_M121_Q1.3351.00
74_G103_Y1.3341.00
312_Q316_L1.3171.00
88_K318_M1.3161.00
96_A125_A1.3151.00
253_L256_P1.3071.00
291_F294_A1.2951.00
69_F138_M1.2911.00
99_D104_G1.2831.00
150_W157_E1.2791.00
86_Y97_V1.2761.00
68_V126_L1.2741.00
163_A166_I1.2741.00
69_F95_I1.2521.00
53_K101_A1.2401.00
92_E322_R1.2281.00
216_T219_E1.2261.00
141_S303_H1.2191.00
46_T50_V1.2181.00
88_K91_K1.2121.00
148_M163_A1.2061.00
312_Q315_K1.2051.00
98_V125_A1.1871.00
149_Y152_Q1.1861.00
162_I262_L1.1811.00
77_A105_Y1.1681.00
138_M164_M1.1601.00
77_A99_D1.1471.00
140_H306_Y1.1451.00
265_D284_Y1.1441.00
255_A290_Q1.1381.00
285_E289_A1.1281.00
240_L243_S1.1141.00
67_F93_N1.1091.00
88_K311_D1.1001.00
131_N134_P1.0961.00
126_L131_N1.0891.00
241_L244_Y1.0871.00
127_M154_Y1.0821.00
131_N135_Y1.0801.00
313_I317_S1.0771.00
65_D136_I1.0771.00
60_E90_S1.0711.00
72_G141_S1.0671.00
126_L150_W1.0671.00
74_G141_S1.0611.00
267_V300_R1.0591.00
240_L244_Y1.0551.00
125_A129_S1.0541.00
55_M106_S1.0381.00
66_T93_N1.0281.00
46_T59_Q1.0281.00
185_V189_H1.0271.00
70_M137_L1.0261.00
47_V56_N1.0261.00
274_S285_E1.0201.00
64_K94_K1.0171.00
67_F95_I1.0151.00
311_D315_K1.0141.00
57_V129_S1.0131.00
138_M317_S1.0091.00
90_S95_I1.0071.00
65_D159_K1.0051.00
286_A289_A1.0041.00
77_A80_Y1.0041.00
265_D274_S1.0021.00
140_H304_S0.9981.00
264_L299_L0.9911.00
301_G305_I0.9881.00
77_A97_V0.9831.00
221_E225_A0.9831.00
93_N321_M0.9771.00
264_L316_L0.9751.00
254_P257_K0.9721.00
124_K128_K0.9661.00
135_Y158_I0.9641.00
47_V50_V0.9481.00
119_L146_E0.9451.00
116_D149_Y0.9441.00
48_V57_V0.9431.00
53_K107_E0.9421.00
123_R126_L0.9391.00
295_D316_L0.9391.00
96_A129_S0.9381.00
68_V122_T0.9221.00
198_R201_P0.9151.00
83_K97_V0.9141.00
197_H201_P0.9121.00
84_G87_S0.9101.00
68_V135_Y0.9051.00
50_V124_K0.9001.00
234_A238_H0.8991.00
299_L312_Q0.8921.00
152_Q253_L0.8891.00
117_T120_E0.8871.00
301_G308_Y0.8841.00
70_M98_V0.8821.00
318_M322_R0.8811.00
139_P147_A0.8801.00
268_S300_R0.8781.00
135_Y157_E0.8781.00
187_G191_L0.8761.00
217_D221_E0.8731.00
285_E288_A0.8711.00
123_R153_K0.8661.00
199_F203_A0.8571.00
87_S90_S0.8521.00
86_Y95_I0.8511.00
124_K127_M0.8511.00
302_T308_Y0.8451.00
262_L295_D0.8321.00
160_A260_P0.8301.00
151_A158_I0.8281.00
161_I261_V0.8271.00
112_D117_T0.8271.00
266_A305_I0.8241.00
297_K319_E0.8161.00
48_V128_K0.8001.00
58_Y83_K0.7961.00
300_R309_Q0.7921.00
119_L153_K0.7901.00
55_M101_A0.7891.00
137_L150_W0.7881.00
56_N106_S0.7871.00
139_P144_G0.7851.00
165_D265_D0.7841.00
265_D296_I0.7821.00
188_F192_T0.7821.00
69_F82_M0.7801.00
120_E123_R0.7801.00
186_R189_H0.7741.00
258_E292_N0.7621.00
65_D93_N0.7591.00
99_D105_Y0.7581.00
120_E124_K0.7571.00
67_F138_M0.7561.00
184_K187_G0.7541.00
164_M306_Y0.7521.00
100_R142_I0.7501.00
118_V142_I0.7491.00
249_K252_N0.7491.00
140_H165_D0.7471.00
225_A229_K0.7471.00
164_M305_I0.7461.00
77_A98_V0.7371.00
222_I225_A0.7331.00
149_Y253_L0.7321.00
100_R118_V0.7321.00
237_E240_L0.7291.00
81_E306_Y0.7281.00
265_D298_E0.7271.00
191_L194_I0.7271.00
160_A320_F0.7261.00
130_G134_P0.7261.00
285_E298_E0.7251.00
91_K318_M0.7171.00
87_S91_K0.7171.00
221_E224_K0.7161.00
263_I294_A0.7141.00
65_D134_P0.7131.00
226_I229_K0.7101.00
165_D305_I0.7071.00
60_E87_S0.7071.00
158_I259_T0.7071.00
297_K312_Q0.7071.00
139_P143_S0.7071.00
314_Y318_M0.7041.00
162_I321_M0.7041.00
257_K261_V0.7031.00
236_M240_L0.7031.00
264_L313_I0.7021.00
219_E222_I0.7021.00
201_P204_V0.7011.00
226_I230_Q0.6991.00
137_L158_I0.6991.00
246_N249_K0.6991.00
74_G142_I0.6981.00
66_T135_Y0.6981.00
93_N318_M0.6971.00
299_L309_Q0.6951.00
183_L186_R0.6941.00
211_R214_F0.6941.00
71_S98_V0.6921.00
94_K131_N0.6911.00
62_S94_K0.6901.00
239_E242_Q0.6901.00
119_L150_W0.6881.00
212_Q215_L0.6861.00
50_V53_K0.6861.00
195_G198_R0.6851.00
183_L187_G0.6801.00
209_V212_Q0.6791.00
267_V274_S0.6741.00
238_H242_Q0.6741.00
189_H193_S0.6721.00
242_Q245_Q0.6721.00
218_E222_I0.6691.00
135_Y159_K0.6661.00
63_G94_K0.6621.00
88_K92_E0.6591.00
63_G66_T0.6561.00
93_N322_R0.6551.00
284_Y288_A0.6541.00
269_D303_H0.6531.00
68_V137_L0.6471.00
218_E221_E0.6401.00
160_A321_M0.6401.00
144_G163_A0.6391.00
116_D120_E0.6371.00
101_A118_V0.6341.00
69_F97_V0.6341.00
190_L194_I0.6331.00
236_M239_E0.6311.00
222_I226_I0.6281.00
202_S205_Y0.6261.00
85_L313_I0.6251.00
118_V146_E0.6251.00
238_H241_L0.6241.00
162_I264_L0.6211.00
288_A296_I0.6201.00
263_I291_F0.6191.00
151_A259_T0.6181.00
237_E241_L0.6171.00
188_F191_L0.6161.00
73_S142_I0.6151.00
275_K285_E0.6131.00
203_A206_N0.6121.00
184_K188_F0.6111.00
100_R103_Y0.6101.00
187_G190_L0.6101.00
140_H164_M0.6091.00
227_N231_F0.6081.00
67_F136_I0.6071.00
284_Y296_I0.6041.00
85_L88_K0.6041.00
198_R202_S0.6011.00
190_L193_S0.6011.00
120_E154_Y0.5981.00
138_M162_I0.5981.00
184_K191_L0.5981.00
100_R122_T0.5971.00
148_M166_I0.5951.00
68_V98_V0.5911.00
83_K87_S0.5891.00
51_D120_E0.5881.00
310_P314_Y0.5871.00
285_E296_I0.5871.00
184_K194_I0.5841.00
185_V188_F0.5841.00
315_K318_M0.5831.00
70_M146_E0.5821.00
283_D286_A0.5811.00
212_Q216_T0.5781.00
132_K157_E0.5781.00
268_S301_G0.5771.00
96_A131_N0.5761.00
47_V57_V0.5751.00
151_A257_K0.5751.00
196_F204_V0.5731.00
102_G113_R0.5721.00
51_D117_T0.5711.00
126_L157_E0.5701.00
186_R191_L0.5691.00
82_M85_L0.5661.00
241_L245_Q0.5651.00
200_I203_A0.5621.00
115_I149_Y0.5621.00
224_K228_F0.5611.00
319_E322_R0.5591.00
196_F203_A0.5591.00
235_D238_H0.5581.00
162_I320_F0.5581.00
263_I284_Y0.5571.00
67_F89_F0.5561.00
257_K291_F0.5561.00
145_I167_G0.5551.00
267_V299_L0.5551.00
233_N236_M0.5541.00
142_I146_E0.5541.00
141_S304_S0.5531.00
67_F321_M0.5521.00
223_Y226_I0.5521.00
195_G203_A0.5491.00
191_L195_G0.5491.00
72_G140_H0.5461.00
233_N237_E0.5451.00
80_Y83_K0.5441.00
148_M168_L0.5441.00
225_A228_F0.5421.00
295_D319_E0.5421.00
186_R190_L0.5411.00
239_E243_S0.5391.00
200_I204_V0.5371.00
86_Y90_S0.5351.00
152_Q256_P0.5331.00
65_D160_A0.5331.00
201_P205_Y0.5311.00
296_I299_L0.5271.00
84_G219_E0.5251.00
59_Q129_S0.5241.00
265_D272_R0.5221.00
82_M86_Y0.5191.00
235_D239_E0.5181.00
247_G250_S0.5131.00
263_I288_A0.5131.00
135_Y150_W0.5131.00
49_D52_G0.5101.00
197_H204_V0.5091.00
140_H305_I0.5081.00
101_A109_S0.5071.00
73_S103_Y0.5061.00
134_P157_E0.5061.00
314_Y319_E0.5051.00
306_Y313_I0.5051.00
184_K192_T0.5051.00
75_I304_S0.5031.00
119_L123_R0.5021.00
195_G202_S0.5011.00
220_K224_K0.5001.00
197_H202_S0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4inzA 1 0.8185 100 0.253 Contact Map
3om8A 4 0.8123 100 0.257 Contact Map
1ehyA 1 0.8062 100 0.266 Contact Map
2xuaA 2 0.7938 100 0.274 Contact Map
3oosA 1 0.8062 100 0.276 Contact Map
3r40A 2 0.8369 100 0.279 Contact Map
4ns4A 1 0.8123 100 0.281 Contact Map
2pujA 4 0.8277 100 0.282 Contact Map
4psuA 1 0.8431 100 0.286 Contact Map
2wueA 4 0.8277 100 0.29 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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