YISQ - BACSU - GREMLIN Contacts

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YISQ - Uncharacterized transporter YisQ

UniProt:	O07940	Sequences: MKQAVFKSTALKKPADKTFSLFSLTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTVIISQFLGSRQKKEAMEVAYVSIGANFFISLAISAVVFFAAVPLLHMMGLSDALMPDAKVFLQVVGGLSFIQALIMTFSAILKSYGYTKDTMFVTIGMNILNIAGNFVVIFGLFGFPVLGVAGVAMSTSIARVIGLIAMIVIVNKRIQLKMSLKKVFHMHKEHLRKLLKIGIPSAGEQLSYNLSQMIVTYFIAIMGAQALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGGKQFDAAYERCMKSLYWALGIAAATSVLMTIFSKDLIGLFTQSPDIIATASLLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMAMISMWGIGLPLAYLFGIHLGFGLAGIWISFIADEWVRGILMYRRWRSRIWIQKGMA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	455 (423)
Sequences:	17914 (13409)
Seq/√Len:	652.0

ECOLI - YEEO DINF MDTK
BACSU - YISQ YOEA NORM YPNP
HALSA - Q9HMS7 Q9HRF7 Q9HN79 Q9HRF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
90_Q	93_E	4.704	1.00
150_I	212_V	3.913	1.00
139_V	201_A	3.367	1.00
83_S	308_G	3.106	1.00
58_G	283_V	3.096	1.00
349_I	362_A	3.085	1.00
121_V	138_K	3.028	1.00
344_F	347_D	3.016	1.00
244_R	248_K	2.870	1.00
166_Y	169_D	2.774	1.00
121_V	125_H	2.710	1.00
119_A	122_P	2.699	1.00
315_Q	318_A	2.694	1.00
143_V	201_A	2.537	1.00
187_V	192_L	2.519	1.00
180_L	213_I	2.512	1.00
78_T	101_S	2.487	1.00
240_K	244_R	2.478	1.00
45_M	189_I	2.407	1.00
138_K	142_Q	2.386	1.00
85_F	93_E	2.344	1.00
45_M	186_F	2.325	1.00
391_D	443_R	2.315	1.00
56_A	136_D	2.289	1.00
52_N	132_A	2.289	1.00
19_F	23_S	2.168	1.00
177_M	214_G	2.165	1.00
136_D	139_V	2.111	1.00
173_V	217_A	2.093	1.00
153_L	215_L	2.092	1.00
50_S	53_S	2.071	1.00
324_M	328_Y	2.028	1.00
96_E	239_H	1.999	1.00
303_T	326_S	1.998	1.00
364_L	423_A	1.984	1.00
143_V	204_A	1.984	1.00
281_T	361_T	1.964	1.00
201_A	205_M	1.959	1.00
130_S	276_A	1.951	1.00
421_G	424_G	1.943	1.00
356_P	360_A	1.941	1.00
198_L	205_M	1.924	1.00
345_S	367_A	1.918	1.00
42_D	207_T	1.915	1.00
135_P	139_V	1.914	1.00
46_L	203_V	1.913	1.00
147_L	208_S	1.898	1.00
189_I	203_V	1.890	1.00
187_V	191_G	1.875	1.00
29_F	298_A	1.857	1.00
105_N	156_T	1.843	1.00
310_Y	318_A	1.828	1.00
51_D	355_S	1.825	1.00
357_D	360_A	1.814	1.00
26_W	30_I	1.802	1.00
45_M	185_N	1.801	1.00
346_K	363_S	1.797	1.00
85_F	90_Q	1.772	1.00
125_H	134_M	1.753	1.00
168_K	172_F	1.720	1.00
192_L	197_V	1.707	1.00
120_A	138_K	1.691	1.00
85_F	88_S	1.676	1.00
191_G	197_V	1.669	1.00
146_G	149_F	1.666	1.00
143_V	205_M	1.657	1.00
173_V	218_M	1.653	1.00
311_I	389_A	1.653	1.00
345_S	363_S	1.653	1.00
216_I	220_V	1.648	1.00
306_L	322_R	1.646	1.00
375_G	434_W	1.641	1.00
150_I	215_L	1.637	1.00
25_T	302_G	1.636	1.00
321_E	324_M	1.630	1.00
342_T	367_A	1.617	1.00
179_I	183_A	1.609	1.00
239_H	242_H	1.596	1.00
122_P	125_H	1.588	1.00
323_C	382_I	1.580	1.00
81_I	97_V	1.571	1.00
330_A	377_S	1.571	1.00
186_F	190_F	1.558	1.00
185_N	203_V	1.557	1.00
41_A	182_I	1.553	1.00
320_Y	324_M	1.549	1.00
311_I	319_A	1.530	1.00
186_F	192_L	1.528	1.00
143_V	208_S	1.523	1.00
134_M	138_K	1.522	1.00
346_K	350_G	1.510	1.00
321_E	325_K	1.501	1.00
184_G	206_S	1.490	1.00
338_S	342_T	1.459	1.00
391_D	394_F	1.455	1.00
120_A	142_Q	1.453	1.00
347_D	350_G	1.449	1.00
157_F	218_M	1.446	1.00
113_S	149_F	1.444	1.00
188_V	192_L	1.442	1.00
183_A	187_V	1.441	1.00
180_L	184_G	1.437	1.00
350_G	359_I	1.426	1.00
116_V	145_G	1.424	1.00
60_S	141_L	1.421	1.00
317_D	321_E	1.419	1.00
121_V	135_P	1.415	1.00
131_D	135_P	1.410	1.00
125_H	131_D	1.401	1.00
277_Q	357_D	1.400	1.00
438_I	442_R	1.394	1.00
323_C	385_S	1.391	1.00
46_L	57_V	1.390	1.00
310_Y	315_Q	1.382	1.00
420_F	424_G	1.378	1.00
18_T	325_K	1.376	1.00
368_M	427_I	1.372	1.00
132_A	135_P	1.372	1.00
42_D	181_N	1.371	1.00
124_L	134_M	1.370	1.00
183_A	186_F	1.368	1.00
85_F	97_V	1.367	1.00
17_K	306_L	1.352	1.00
328_Y	332_G	1.340	1.00
220_V	224_K	1.339	1.00
91_K	95_M	1.338	1.00
172_F	176_G	1.331	1.00
30_I	171_M	1.331	1.00
188_V	198_L	1.328	1.00
53_S	136_D	1.321	1.00
92_K	96_E	1.320	1.00
347_D	351_L	1.319	1.00
132_A	276_A	1.315	1.00
93_E	96_E	1.314	1.00
201_A	204_A	1.314	1.00
342_T	370_I	1.310	1.00
413_L	417_H	1.306	1.00
330_A	381_I	1.303	1.00
84_Q	308_G	1.298	1.00
87_G	312_G	1.297	1.00
442_R	445_R	1.294	1.00
55_A	280_T	1.283	1.00
360_A	364_L	1.283	1.00
49_Y	190_F	1.283	1.00
121_V	134_M	1.282	1.00
86_L	309_R	1.281	1.00
363_S	367_A	1.280	1.00
34_L	175_I	1.277	1.00
84_Q	88_S	1.275	1.00
441_Y	445_R	1.260	1.00
184_G	209_I	1.257	1.00
394_F	443_R	1.253	1.00
412_Y	416_I	1.250	1.00
122_P	126_M	1.250	1.00
86_L	94_A	1.244	1.00
349_I	359_I	1.238	1.00
406_I	435_V	1.231	1.00
288_I	348_L	1.227	1.00
173_V	221_I	1.224	1.00
93_E	242_H	1.217	1.00
393_K	397_Y	1.210	1.00
18_T	329_W	1.203	1.00
339_V	343_I	1.198	1.00
181_N	207_T	1.187	1.00
401_I	405_G	1.186	1.00
43_T	287_N	1.186	1.00
241_E	244_R	1.181	1.00
185_N	206_S	1.175	1.00
176_G	217_A	1.164	1.00
316_F	320_Y	1.164	1.00
188_V	209_I	1.164	1.00
251_I	255_G	1.159	1.00
420_F	427_I	1.157	1.00
186_F	189_I	1.151	1.00
117_F	142_Q	1.151	1.00
43_T	54_V	1.151	1.00
56_A	133_L	1.139	1.00
124_L	137_A	1.136	1.00
231_S	234_K	1.134	1.00
84_Q	390_G	1.133	1.00
100_V	238_M	1.124	1.00
52_N	136_D	1.120	1.00
113_S	117_F	1.114	1.00
238_M	243_L	1.111	1.00
300_S	384_N	1.110	1.00
48_Q	190_F	1.109	1.00
51_D	277_Q	1.109	1.00
307_I	319_A	1.105	1.00
57_V	200_V	1.096	1.00
186_F	191_G	1.095	1.00
98_A	160_I	1.090	1.00
21_L	326_S	1.090	1.00
100_V	243_L	1.087	1.00
82_I	163_S	1.084	1.00
48_Q	354_Q	1.083	1.00
359_I	362_A	1.080	1.00
424_G	428_S	1.079	1.00
166_Y	170_T	1.078	1.00
361_T	364_L	1.067	1.00
409_P	413_L	1.065	1.00
188_V	191_G	1.060	1.00
278_A	422_L	1.054	1.00
104_A	243_L	1.053	1.00
323_C	444_W	1.051	1.00
379_N	433_E	1.049	1.00
398_M	440_M	1.047	1.00
180_L	210_A	1.046	1.00
285_T	365_L	1.042	1.00
42_D	185_N	1.041	1.00
191_G	198_L	1.038	1.00
397_Y	401_I	1.029	1.00
417_H	420_F	1.027	1.00
386_L	443_R	1.026	1.00
105_N	152_A	1.019	1.00
16_D	19_F	1.013	1.00
353_T	358_I	1.011	1.00
332_G	336_A	1.003	1.00
169_D	221_I	1.003	1.00
382_I	444_W	1.002	1.00
142_Q	146_G	1.001	1.00
405_G	409_P	1.001	1.00
113_S	146_G	1.000	1.00
270_F	274_M	0.996	1.00
95_M	234_K	0.993	1.00
96_E	242_H	0.991	1.00
118_F	122_P	0.990	1.00
106_F	153_L	0.989	1.00
165_G	309_R	0.986	1.00
87_G	313_G	0.983	1.00
22_F	26_W	0.980	1.00
97_V	242_H	0.979	1.00
245_K	248_K	0.978	1.00
269_Y	273_I	0.978	1.00
192_L	198_L	0.976	1.00
325_K	329_W	0.975	1.00
101_S	246_L	0.968	1.00
175_I	179_I	0.958	1.00
205_M	208_S	0.956	1.00
360_A	363_S	0.952	1.00
103_G	238_M	0.952	1.00
346_K	360_A	0.951	1.00
310_Y	322_R	0.949	1.00
39_G	61_N	0.947	1.00
86_L	164_Y	0.945	1.00
365_L	422_L	0.945	1.00
99_Y	235_V	0.940	1.00
185_N	207_T	0.938	1.00
414_F	420_F	0.934	1.00
71_F	152_A	0.931	1.00
298_A	302_G	0.930	1.00
284_Y	352_F	0.929	1.00
86_L	91_K	0.928	1.00
288_I	341_M	0.926	1.00
368_M	423_A	0.925	1.00
120_A	141_L	0.924	1.00
335_A	339_V	0.919	1.00
59_V	129_L	0.915	1.00
118_F	142_Q	0.911	1.00
49_Y	197_V	0.910	1.00
157_F	215_L	0.908	1.00
161_L	222_V	0.907	1.00
52_N	276_A	0.904	1.00
336_A	340_L	0.902	1.00
44_L	47_S	0.901	1.00
184_G	188_V	0.899	1.00
84_Q	311_I	0.898	1.00
432_D	436_R	0.895	1.00
208_S	212_V	0.895	1.00
139_V	142_Q	0.891	1.00
375_G	437_G	0.888	1.00
259_S	400_M	0.883	1.00
319_A	323_C	0.882	1.00
281_T	358_I	0.880	1.00
28_I	301_Q	0.878	1.00
349_I	363_S	0.878	1.00
336_A	339_V	0.877	1.00
342_T	346_K	0.877	1.00
41_A	181_N	0.871	1.00
20_S	23_S	0.869	1.00
136_D	200_V	0.866	1.00
176_G	180_L	0.865	1.00
327_L	378_F	0.865	1.00
410_L	431_A	0.863	1.00
212_V	216_I	0.863	1.00
34_L	178_N	0.862	1.00
319_A	389_A	0.857	1.00
343_I	347_D	0.856	1.00
107_F	111_A	0.855	1.00
131_D	134_M	0.853	1.00
359_I	363_S	0.852	1.00
428_S	432_D	0.850	1.00
357_D	361_T	0.849	1.00
52_N	133_L	0.845	1.00
213_I	217_A	0.844	1.00
55_A	133_L	0.841	1.00
154_I	214_G	0.840	1.00
307_I	385_S	0.839	1.00
114_A	118_F	0.839	1.00
45_M	190_F	0.836	1.00
181_N	185_N	0.834	1.00
255_G	396_V	0.833	1.00
41_A	178_N	0.833	1.00
282_K	426_W	0.832	1.00
64_L	144_V	0.829	1.00
307_I	388_A	0.828	1.00
84_Q	245_K	0.827	1.00
166_Y	221_I	0.826	1.00
410_L	414_F	0.826	1.00
277_Q	361_T	0.825	1.00
281_T	362_A	0.825	1.00
78_T	82_I	0.824	1.00
278_A	361_T	0.822	1.00
310_Y	313_G	0.817	1.00
296_G	334_A	0.815	1.00
111_A	115_V	0.814	1.00
24_L	167_T	0.814	1.00
321_E	328_Y	0.812	1.00
406_I	409_P	0.809	1.00
172_F	175_I	0.809	1.00
146_G	208_S	0.805	1.00
143_V	146_G	0.805	1.00
171_M	175_I	0.801	1.00
205_M	209_I	0.801	1.00
217_A	220_V	0.800	1.00
70_M	254_A	0.795	1.00
271_I	422_L	0.795	1.00
402_S	436_R	0.794	1.00
423_A	427_I	0.794	1.00
157_F	222_V	0.793	1.00
248_K	393_K	0.792	1.00
287_N	352_F	0.789	1.00
115_V	119_A	0.787	1.00
411_A	415_G	0.787	1.00
120_A	145_G	0.784	1.00
117_F	121_V	0.784	1.00
318_A	321_E	0.783	1.00
299_I	326_S	0.780	1.00
332_G	335_A	0.777	1.00
21_L	325_K	0.776	1.00
414_F	424_G	0.773	1.00
101_S	156_T	0.772	1.00
133_L	279_L	0.767	1.00
325_K	328_Y	0.767	1.00
356_P	359_I	0.767	1.00
51_D	358_I	0.767	1.00
82_I	160_I	0.767	1.00
284_Y	362_A	0.766	1.00
80_V	84_Q	0.766	1.00
83_S	163_S	0.765	1.00
99_Y	234_K	0.764	1.00
46_L	189_I	0.762	1.00
161_L	218_M	0.759	1.00
378_F	437_G	0.759	1.00
326_S	381_I	0.756	1.00
20_S	309_R	0.755	1.00
18_T	22_F	0.755	1.00
92_K	234_K	0.753	1.00
52_N	55_A	0.749	1.00
166_Y	225_R	0.749	1.00
139_V	200_V	0.747	1.00
220_V	223_N	0.747	1.00
56_A	200_V	0.746	1.00
274_M	278_A	0.745	1.00
81_I	249_I	0.744	1.00
31_E	174_T	0.744	1.00
128_G	131_D	0.744	1.00
250_G	254_A	0.743	1.00
281_T	365_L	0.741	1.00
38_M	207_T	0.741	1.00
185_N	189_I	0.741	1.00
270_F	412_Y	0.740	1.00
434_W	438_I	0.740	1.00
331_L	335_A	0.740	1.00
103_G	107_F	0.740	1.00
162_K	170_T	0.738	1.00
274_M	415_G	0.737	1.00
47_S	54_V	0.736	1.00
37_F	41_A	0.735	1.00
34_L	37_F	0.731	1.00
161_L	169_D	0.731	1.00
317_D	324_M	0.728	1.00
181_N	210_A	0.727	1.00
81_I	85_F	0.727	1.00
20_S	306_L	0.727	1.00
242_H	245_K	0.726	1.00
335_A	374_P	0.726	1.00
307_I	323_C	0.726	1.00
40_N	291_F	0.725	1.00
135_P	138_K	0.725	1.00
355_S	359_I	0.724	1.00
88_S	312_G	0.722	1.00
371_I	374_P	0.722	1.00
197_V	201_A	0.722	1.00
21_L	302_G	0.721	1.00
245_K	390_G	0.714	1.00
345_S	366_I	0.709	1.00
384_N	388_A	0.708	1.00
270_F	273_I	0.706	1.00
25_T	298_A	0.705	1.00
271_I	425_I	0.705	1.00
111_A	114_A	0.704	1.00
18_T	328_Y	0.703	1.00
95_M	231_S	0.702	1.00
44_L	351_L	0.702	1.00
119_A	123_L	0.699	1.00
299_I	333_I	0.699	1.00
331_L	377_S	0.698	1.00
317_D	320_Y	0.697	1.00
56_A	137_A	0.697	1.00
424_G	427_I	0.696	1.00
328_Y	331_L	0.695	1.00
272_A	279_L	0.693	1.00
368_M	430_I	0.692	1.00
204_A	208_S	0.691	1.00
310_Y	319_A	0.691	1.00
140_F	185_N	0.690	1.00
169_D	217_A	0.685	1.00
41_A	45_M	0.684	1.00
109_S	149_F	0.683	1.00
124_L	141_L	0.683	1.00
334_A	377_S	0.682	1.00
394_F	398_M	0.682	1.00
258_L	262_L	0.681	1.00
224_K	227_Q	0.680	1.00
408_L	412_Y	0.679	1.00
344_F	348_L	0.677	1.00
299_I	330_A	0.677	1.00
247_L	251_I	0.677	1.00
303_T	307_I	0.675	1.00
274_M	277_Q	0.675	1.00
219_I	223_N	0.673	1.00
345_S	349_I	0.673	1.00
46_L	53_S	0.672	1.00
93_E	97_V	0.671	1.00
141_L	145_G	0.671	1.00
427_I	430_I	0.668	1.00
249_I	392_A	0.665	1.00
333_I	337_T	0.665	1.00
82_I	94_A	0.664	1.00
209_I	212_V	0.663	1.00
176_G	213_I	0.662	1.00
273_I	277_Q	0.662	1.00
145_G	148_S	0.662	1.00
180_L	209_I	0.661	1.00
198_L	201_A	0.660	1.00
147_L	150_I	0.660	1.00
73_F	254_A	0.653	1.00
114_A	117_F	0.652	1.00
44_L	48_Q	0.651	1.00
316_F	319_A	0.651	1.00
342_T	345_S	0.650	1.00
346_K	359_I	0.649	1.00
415_G	424_G	0.647	1.00
49_Y	53_S	0.646	1.00
353_T	356_P	0.644	1.00
406_I	410_L	0.643	1.00
145_G	149_F	0.643	1.00
121_V	142_Q	0.642	1.00
92_K	95_M	0.641	1.00
132_A	136_D	0.640	1.00
228_L	232_L	0.639	1.00
147_L	211_R	0.636	1.00
270_F	411_A	0.635	1.00
53_S	199_G	0.635	1.00
367_A	371_I	0.631	1.00
146_G	150_I	0.631	1.00
295_F	333_I	0.631	1.00
142_Q	201_A	0.627	1.00
133_L	136_D	0.627	1.00
267_V	425_I	0.625	1.00
252_P	396_V	0.625	1.00
210_A	213_I	0.622	1.00
413_L	416_I	0.622	1.00
96_E	99_Y	0.620	1.00
38_M	211_R	0.620	1.00
38_M	177_M	0.619	1.00
54_V	284_Y	0.618	1.00
80_V	249_I	0.618	1.00
311_I	316_F	0.617	1.00
266_I	408_L	0.617	1.00
88_S	314_K	0.616	1.00
289_T	373_E	0.616	1.00
33_S	37_F	0.616	1.00
46_L	200_V	0.616	1.00
271_I	282_K	0.615	1.00
188_V	203_V	0.615	1.00
157_F	219_I	0.613	1.00
54_V	353_T	0.612	1.00
20_S	318_A	0.611	1.00
175_I	178_N	0.610	1.00
103_G	235_V	0.610	1.00
343_I	346_K	0.609	1.00
340_L	344_F	0.608	1.00
386_L	391_D	0.606	1.00
106_F	110_L	0.604	1.00
223_N	226_I	0.603	1.00
278_A	281_T	0.603	1.00
134_M	137_A	0.603	1.00
37_F	178_N	0.599	1.00
96_E	100_V	0.598	1.00
109_S	145_G	0.597	1.00
181_N	206_S	0.596	1.00
422_L	426_W	0.596	1.00
275_G	278_A	0.596	1.00
223_N	229_K	0.596	1.00
53_S	56_A	0.596	1.00
16_D	20_S	0.595	1.00
92_K	233_K	0.594	1.00
382_I	440_M	0.594	1.00
188_V	205_M	0.594	1.00
398_M	439_L	0.593	1.00
117_F	146_G	0.592	1.00
158_S	162_K	0.591	1.00
385_S	389_A	0.591	1.00
370_I	374_P	0.591	1.00
292_I	337_T	0.590	1.00
55_A	58_G	0.588	1.00
154_I	215_L	0.587	1.00
110_L	114_A	0.587	1.00
309_R	313_G	0.586	1.00
124_L	138_K	0.585	1.00
80_V	308_G	0.585	1.00
273_I	416_I	0.583	1.00
281_T	426_W	0.583	1.00
190_F	198_L	0.582	1.00
106_F	109_S	0.580	1.00
17_K	321_E	0.580	1.00
304_Q	387_R	0.579	1.00
331_L	378_F	0.579	1.00
392_A	396_V	0.577	1.00
90_Q	96_E	0.577	1.00
180_L	183_A	0.577	1.00
61_N	65_N	0.574	1.00
217_A	221_I	0.574	1.00
293_L	376_R	0.573	1.00
51_D	280_T	0.572	1.00
378_F	441_Y	0.572	1.00
139_V	143_V	0.572	1.00
427_I	431_A	0.571	1.00
410_L	413_L	0.570	1.00
241_E	245_K	0.569	1.00
412_Y	415_G	0.568	1.00
327_L	331_L	0.568	1.00
79_T	159_A	0.567	1.00
329_W	332_G	0.565	1.00
109_S	113_S	0.565	1.00
176_G	179_I	0.564	1.00
74_I	254_A	0.564	1.00
414_F	417_H	0.563	1.00
49_Y	186_F	0.561	1.00
99_Y	103_G	0.561	1.00
140_F	203_V	0.560	1.00
17_K	325_K	0.559	1.00
110_L	113_S	0.559	1.00
290_M	293_L	0.557	1.00
251_I	254_A	0.557	1.00
410_L	428_S	0.555	1.00
296_G	377_S	0.554	1.00
439_L	442_R	0.553	1.00
407_G	432_D	0.553	1.00
94_A	98_A	0.551	1.00
82_I	97_V	0.551	1.00
270_F	415_G	0.549	1.00
100_V	242_H	0.548	1.00
129_L	134_M	0.547	1.00
74_I	108_I	0.546	1.00
353_T	359_I	0.545	1.00
133_L	137_A	0.545	1.00
154_I	158_S	0.544	1.00
289_T	369_T	0.542	1.00
402_S	439_L	0.542	1.00
358_I	362_A	0.540	1.00
399_A	402_S	0.540	1.00
28_I	298_A	0.538	1.00
379_N	436_R	0.538	1.00
270_F	416_I	0.538	1.00
173_V	214_G	0.538	1.00
285_T	366_I	0.537	1.00
382_I	441_Y	0.537	1.00
21_L	25_T	0.535	1.00
149_F	212_V	0.533	0.99
257_Q	297_T	0.533	0.99
22_F	329_W	0.532	0.99
48_Q	353_T	0.532	0.99
21_L	329_W	0.531	0.99
267_V	411_A	0.529	0.99
215_L	219_I	0.529	0.99
331_L	374_P	0.528	0.99
259_S	396_V	0.528	0.99
150_I	208_S	0.528	0.99
410_L	435_V	0.527	0.99
409_P	412_Y	0.525	0.99
162_K	167_T	0.525	0.99
59_V	279_L	0.524	0.99
274_M	421_G	0.524	0.99
113_S	118_F	0.523	0.99
76_T	301_Q	0.523	0.99
324_M	444_W	0.522	0.99
41_A	44_L	0.522	0.99
182_I	186_F	0.522	0.99
39_G	144_V	0.521	0.99
338_S	374_P	0.520	0.99
115_V	118_F	0.520	0.99
129_L	272_A	0.520	0.99
243_L	247_L	0.519	0.99
304_Q	384_N	0.518	0.99
117_F	145_G	0.518	0.99
303_T	381_I	0.518	0.99
59_V	137_A	0.518	0.99
159_A	162_K	0.518	0.99
28_I	167_T	0.518	0.99
17_K	318_A	0.517	0.99
127_M	265_M	0.516	0.99
17_K	322_R	0.516	0.99
117_F	120_A	0.516	0.99
411_A	425_I	0.514	0.99
89_R	313_G	0.513	0.99
421_G	428_S	0.510	0.99
221_I	225_R	0.510	0.99
263_S	403_M	0.510	0.99
412_Y	417_H	0.509	0.99
65_N	261_N	0.508	0.99
45_M	206_S	0.507	0.99
37_F	40_N	0.506	0.99
364_L	367_A	0.506	0.99
123_L	126_M	0.506	0.99
113_S	145_G	0.505	0.99
284_Y	358_I	0.505	0.99
323_C	327_L	0.505	0.99
401_I	439_L	0.503	0.99
77_G	250_G	0.503	0.99
169_D	225_R	0.501	0.99
110_L	149_F	0.500	0.99
124_L	129_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mktA	1	0.9824	100	0.289	Contact Map
4humA	1	0.989	100	0.302	Contact Map
4lz6A	1	0.9692	100	0.324	Contact Map
3w4tA	1	0.9692	100	0.374	Contact Map
4ikvA	1	0.8901	89.4	0.936	Contact Map
4xnjA	1	0.8659	65.8	0.949	Contact Map
3wdoA	1	0.8527	56.1	0.952	Contact Map
3o7qA	1	0.8308	51.2	0.954	Contact Map
1pw4A	1	0.8879	47.3	0.955	Contact Map
4w6vA	1	0.8747	27.4	0.96	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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