YRAM - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YRAM - Putative isomerase YraM

UniProt:	O07931	Sequences: MVKTNVTIMRGGTSKGVFFHESAMPNNKNEWEPFLLDVMGSPDKRQIDGLGGGNSLTSKVAIIKKAYTSDIDVHYTFGQVSISEEKVDFKGNCGNISAAVGPFAIEEGLVKAKEPMTAVRILNTNTNKMIIAEVEVEDGQVKYDGDVTISGVPGSGSPIYLNFHDAAGSVTGHLLPTGNSSEFLDTSQGQIEVSIIDYANPLVFVEASSIGLDGTELAEEFTDLQLAQFEELRSIAAEKCGFASRFSATKLSPAVPKLAIVAKPEKYKDSTGAWHSSVEMDLHIRMMSMQKPHQALAVTGAICTTRALSVEGAIPARIAKNHSTKVRLAHSSGIIETMVEPTGIKIVRTARRIMDGTVYTHGDYQMM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	367 (338)
Sequences:	1274 (726)
Seq/√Len:	39.5

ECOLI - YBHH
BACSU - YRAM

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
206_E	209_S	5.102	1.00
121_I	132_A	4.549	1.00
18_F	99_A	4.181	1.00
206_E	317_R	3.415	1.00
68_T	122_L	3.192	1.00
179_N	182_E	3.138	1.00
175_L	180_S	3.118	1.00
19_F	38_V	3.111	1.00
76_T	124_T	3.080	1.00
63_I	103_F	2.964	1.00
183_F	192_E	2.847	1.00
148_T	155_S	2.827	1.00
38_V	358_V	2.805	1.00
17_V	38_V	2.717	1.00
122_L	127_N	2.713	1.00
327_R	334_I	2.628	1.00
184_L	235_I	2.525	1.00
56_L	294_Q	2.397	1.00
284_I	296_L	2.351	1.00
215_T	262_A	2.335	1.00
212_L	223_D	2.326	1.00
71_I	129_M	2.298	1.00
20_H	107_E	2.291	1.00
280_M	329_A	2.183	0.99
22_S	65_K	2.179	0.99
175_L	313_A	2.140	0.99
205_V	232_L	2.089	0.99
182_E	239_K	2.056	0.99
54_N	294_Q	2.053	0.99
147_V	347_V	2.051	0.99
181_S	192_E	2.039	0.99
132_A	161_L	2.031	0.99
235_I	239_K	2.028	0.99
184_L	236_A	1.952	0.99
78_G	87_V	1.949	0.99
261_V	315_P	1.941	0.99
117_T	136_V	1.935	0.99
18_F	96_I	1.887	0.98
73_V	101_G	1.886	0.98
262_A	283_H	1.867	0.98
180_S	313_A	1.854	0.98
222_T	292_P	1.850	0.98
55_S	288_S	1.837	0.98
286_M	300_G	1.804	0.98
355_D	359_Y	1.776	0.97
73_V	110_V	1.769	0.97
15_K	353_I	1.764	0.97
308_L	315_P	1.744	0.97
17_V	50_L	1.741	0.97
195_I	240_C	1.724	0.97
105_I	134_V	1.716	0.97
296_L	304_T	1.689	0.97
217_L	220_E	1.680	0.96
175_L	194_S	1.677	0.96
184_L	239_K	1.676	0.96
4_T	34_F	1.673	0.96
192_E	317_R	1.640	0.96
3_K	357_T	1.630	0.96
286_M	297_A	1.604	0.95
158_P	347_V	1.594	0.95
8_I	50_L	1.575	0.95
61_A	96_I	1.571	0.95
218_A	294_Q	1.569	0.95
221_F	287_M	1.566	0.95
298_V	346_I	1.564	0.95
78_G	89_F	1.553	0.94
16_G	96_I	1.550	0.94
11_G	99_A	1.548	0.94
203_V	232_L	1.526	0.94
181_S	317_R	1.514	0.94
107_E	355_D	1.509	0.93
42_P	83_S	1.508	0.93
106_E	141_V	1.499	0.93
66_A	74_H	1.496	0.93
7_T	352_R	1.487	0.93
294_Q	354_M	1.480	0.93
106_E	143_Y	1.472	0.93
107_E	352_R	1.464	0.92
204_F	261_V	1.461	0.92
32_E	89_F	1.449	0.92
282_L	328_L	1.441	0.92
327_R	336_E	1.435	0.92
7_T	107_E	1.429	0.91
185_D	231_E	1.411	0.91
42_P	85_E	1.388	0.90
92_N	123_N	1.386	0.90
185_D	235_I	1.384	0.90
214_G	262_A	1.381	0.90
210_I	260_I	1.369	0.90
74_H	122_L	1.361	0.89
45_R	54_N	1.361	0.89
310_V	313_A	1.355	0.89
101_G	134_V	1.355	0.89
135_E	158_P	1.354	0.89
213_D	216_E	1.352	0.89
116_M	133_E	1.351	0.89
67_Y	122_L	1.346	0.89
135_E	157_S	1.343	0.89
41_S	83_S	1.340	0.89
185_D	190_Q	1.335	0.88
27_N	30_E	1.329	0.88
205_V	210_I	1.313	0.88
175_L	310_V	1.310	0.87
41_S	58_S	1.298	0.87
167_A	174_L	1.297	0.87
352_R	359_Y	1.295	0.87
215_T	265_E	1.293	0.87
66_A	69_S	1.269	0.86
202_L	259_A	1.266	0.86
202_L	303_C	1.264	0.85
70_D	120_R	1.251	0.85
133_E	162_N	1.244	0.85
35_L	57_T	1.243	0.84
92_N	299_T	1.243	0.84
204_F	304_T	1.239	0.84
106_E	352_R	1.218	0.83
166_A	288_S	1.216	0.83
118_A	133_E	1.209	0.83
91_G	254_A	1.194	0.82
36_L	85_E	1.187	0.82
352_R	355_D	1.183	0.81
118_A	131_I	1.180	0.81
73_V	119_V	1.171	0.81
19_F	23_A	1.168	0.81
78_G	88_D	1.158	0.80
39_M	60_V	1.157	0.80
201_P	257_K	1.151	0.80
194_S	303_C	1.145	0.79
168_G	172_G	1.144	0.79
16_G	99_A	1.142	0.79
257_K	301_A	1.139	0.79
297_A	300_G	1.136	0.79
175_L	196_I	1.132	0.78
6_V	354_M	1.123	0.78
96_I	99_A	1.117	0.77
56_L	297_A	1.112	0.77
34_F	360_T	1.107	0.77
8_I	17_V	1.107	0.77
205_V	229_F	1.106	0.77
204_F	315_P	1.102	0.76
30_E	34_F	1.101	0.76
28_K	32_E	1.097	0.76
123_N	170_V	1.094	0.76
196_I	303_C	1.089	0.76
37_D	360_T	1.081	0.75
263_K	266_K	1.065	0.74
264_P	320_K	1.065	0.74
65_K	111_K	1.061	0.74
220_E	223_D	1.057	0.73
81_S	84_E	1.051	0.73
28_K	31_W	1.049	0.73
215_T	283_H	1.048	0.73
3_K	359_Y	1.047	0.73
47_I	153_P	1.045	0.73
230_E	290_Q	1.041	0.72
191_I	209_S	1.038	0.72
114_E	136_V	1.030	0.71
90_K	253_P	1.028	0.71
261_V	318_I	1.025	0.71
45_R	53_G	1.024	0.71
50_L	358_V	1.020	0.71
36_L	42_P	1.020	0.71
198_Y	303_C	1.020	0.71
50_L	354_M	1.019	0.71
81_S	86_K	1.017	0.70
53_G	57_T	1.009	0.70
20_H	109_L	1.008	0.70
177_T	182_E	1.008	0.70
168_G	171_T	1.004	0.69
295_A	339_V	1.003	0.69
199_A	297_A	1.003	0.69
213_D	262_A	1.002	0.69
218_A	295_A	1.001	0.69
34_F	38_V	0.995	0.69
305_T	337_T	0.994	0.69
46_Q	58_S	0.993	0.69
103_F	107_E	0.989	0.68
208_S	263_K	0.987	0.68
7_T	355_D	0.984	0.68
39_M	358_V	0.980	0.68
101_G	119_V	0.978	0.67
150_S	334_I	0.972	0.67
17_V	96_I	0.967	0.67
8_I	354_M	0.963	0.66
20_H	103_F	0.962	0.66
284_I	328_L	0.960	0.66
97_S	161_L	0.957	0.66
150_S	330_H	0.956	0.66
24_M	31_W	0.953	0.65
211_G	214_G	0.948	0.65
202_L	286_M	0.946	0.65
184_L	193_V	0.946	0.65
137_E	142_K	0.945	0.65
235_I	238_E	0.941	0.64
222_T	291_K	0.938	0.64
37_D	361_H	0.936	0.64
73_V	100_V	0.929	0.63
64_K	124_T	0.928	0.63
236_A	240_C	0.927	0.63
207_A	285_R	0.917	0.62
130_I	299_T	0.916	0.62
353_I	358_V	0.912	0.62
180_S	312_G	0.909	0.62
43_D	53_G	0.908	0.62
55_S	257_K	0.907	0.62
212_L	260_I	0.906	0.61
177_T	195_I	0.905	0.61
207_A	211_G	0.904	0.61
180_S	310_V	0.902	0.61
21_E	64_K	0.902	0.61
33_P	360_T	0.900	0.61
123_N	171_T	0.900	0.61
71_I	74_H	0.890	0.60
116_M	135_E	0.890	0.60
63_I	96_I	0.886	0.60
66_A	122_L	0.880	0.59
159_I	308_L	0.878	0.59
68_T	74_H	0.877	0.59
199_A	303_C	0.871	0.58
292_P	354_M	0.867	0.58
91_G	289_M	0.867	0.58
105_I	117_T	0.863	0.58
54_N	57_T	0.863	0.58
3_K	355_D	0.862	0.58
198_Y	302_I	0.860	0.57
8_I	56_L	0.856	0.57
181_S	314_I	0.855	0.57
162_N	345_K	0.855	0.57
56_L	288_S	0.854	0.57
159_I	350_A	0.851	0.57
282_L	308_L	0.849	0.56
105_I	110_V	0.849	0.56
18_F	100_V	0.849	0.56
261_V	307_A	0.842	0.56
43_D	46_Q	0.841	0.56
212_L	216_E	0.839	0.56
183_F	190_Q	0.830	0.55
97_S	102_P	0.829	0.55
337_T	344_I	0.820	0.54
47_I	57_T	0.820	0.54
168_G	197_D	0.819	0.54
204_F	314_I	0.817	0.54
295_A	332_S	0.817	0.54
64_K	122_L	0.816	0.53
201_P	240_C	0.814	0.53
313_A	316_A	0.804	0.52
122_L	128_K	0.799	0.52
263_K	318_I	0.799	0.52
281_D	329_A	0.798	0.52
195_I	236_A	0.798	0.52
38_V	360_T	0.795	0.52
123_N	126_T	0.790	0.51
169_S	194_S	0.790	0.51
209_S	317_R	0.787	0.51
229_F	287_M	0.787	0.51
71_I	122_L	0.787	0.51
18_F	63_I	0.786	0.51
218_A	222_T	0.784	0.51
29_N	32_E	0.781	0.50
7_T	63_I	0.780	0.50
34_F	37_D	0.778	0.50
261_V	314_I	0.777	0.50
91_G	253_P	0.777	0.50
179_N	239_K	0.771	0.49
307_A	315_P	0.770	0.49
171_T	197_D	0.770	0.49
166_A	299_T	0.769	0.49
199_A	296_L	0.768	0.49
50_L	353_I	0.767	0.49
53_G	84_E	0.767	0.49
34_F	361_H	0.763	0.49
135_E	142_K	0.762	0.49
191_I	205_V	0.761	0.48
121_I	358_V	0.759	0.48
98_A	303_C	0.756	0.48
257_K	288_S	0.753	0.48
33_P	37_D	0.753	0.48
296_L	335_I	0.751	0.48
36_L	53_G	0.750	0.47
265_E	283_H	0.749	0.47
349_T	356_G	0.748	0.47
198_Y	306_R	0.748	0.47
92_N	167_A	0.744	0.47
192_E	209_S	0.743	0.47
130_I	198_Y	0.742	0.47
264_P	318_I	0.737	0.46
131_I	164_H	0.734	0.46
199_A	299_T	0.731	0.46
134_V	141_V	0.731	0.46
169_S	255_V	0.731	0.46
58_S	77_F	0.728	0.45
230_E	234_S	0.726	0.45
302_I	353_I	0.720	0.45
31_W	35_L	0.720	0.45
147_V	158_P	0.719	0.45
55_S	344_I	0.719	0.45
207_A	262_A	0.718	0.45
110_V	120_R	0.717	0.44
251_L	263_K	0.715	0.44
88_D	91_G	0.714	0.44
42_P	46_Q	0.713	0.44
169_S	303_C	0.713	0.44
325_K	336_E	0.708	0.44
213_D	265_E	0.707	0.44
123_N	299_T	0.707	0.44
259_A	284_I	0.706	0.43
296_L	301_A	0.705	0.43
131_I	162_N	0.703	0.43
61_A	75_Y	0.703	0.43
221_F	292_P	0.701	0.43
261_V	317_R	0.701	0.43
117_T	134_V	0.698	0.43
238_E	243_A	0.697	0.43
9_M	352_R	0.694	0.42
92_N	103_F	0.693	0.42
287_M	329_A	0.693	0.42
109_L	301_A	0.692	0.42
257_K	289_M	0.691	0.42
16_G	35_L	0.689	0.42
132_A	157_S	0.687	0.42
6_V	17_V	0.687	0.42
52_G	79_Q	0.685	0.42
166_A	302_I	0.684	0.41
56_L	166_A	0.680	0.41
67_Y	110_V	0.679	0.41
88_D	230_E	0.678	0.41
63_I	107_E	0.677	0.41
288_S	299_T	0.676	0.41
180_S	326_V	0.675	0.41
91_G	237_A	0.673	0.41
16_G	25_P	0.673	0.41
102_P	134_V	0.673	0.41
308_L	319_A	0.671	0.40
114_E	138_D	0.671	0.40
101_G	132_A	0.668	0.40
212_L	226_L	0.667	0.40
10_R	14_S	0.667	0.40
73_V	121_I	0.667	0.40
15_K	96_I	0.667	0.40
56_L	290_Q	0.666	0.40
55_S	166_A	0.664	0.40
193_V	323_S	0.664	0.40
91_G	303_C	0.660	0.39
86_K	239_K	0.659	0.39
90_K	170_V	0.658	0.39
154_G	349_T	0.657	0.39
8_I	295_A	0.653	0.39
195_I	201_P	0.653	0.39
16_G	354_M	0.645	0.38
182_E	191_I	0.643	0.38
148_T	326_V	0.642	0.38
21_E	31_W	0.642	0.38
134_V	159_I	0.641	0.38
242_F	353_I	0.640	0.38
214_G	285_R	0.639	0.38
88_D	254_A	0.638	0.37
24_M	32_E	0.637	0.37
259_A	303_C	0.637	0.37
130_I	161_L	0.635	0.37
120_R	164_H	0.635	0.37
123_N	297_A	0.635	0.37
89_F	123_N	0.634	0.37
149_I	152_V	0.634	0.37
64_K	67_Y	0.633	0.37
99_A	181_S	0.630	0.37
112_A	115_P	0.623	0.36
96_I	199_A	0.623	0.36
169_S	173_H	0.623	0.36
62_I	78_G	0.622	0.36
121_I	131_I	0.621	0.36
184_L	195_I	0.620	0.36
211_G	216_E	0.620	0.36
200_N	298_V	0.617	0.36
6_V	332_S	0.616	0.36
65_K	109_L	0.615	0.36
71_I	120_R	0.615	0.36
116_M	229_F	0.615	0.36
213_D	272_G	0.611	0.35
102_P	157_S	0.610	0.35
10_R	13_T	0.610	0.35
141_V	157_S	0.609	0.35
286_M	299_T	0.607	0.35
231_E	235_I	0.606	0.35
126_T	154_G	0.605	0.35
67_Y	231_E	0.604	0.35
218_A	292_P	0.603	0.35
185_D	265_E	0.603	0.35
203_V	258_L	0.601	0.34
308_L	360_T	0.600	0.34
57_T	302_I	0.600	0.34
194_S	290_Q	0.600	0.34
160_Y	347_V	0.599	0.34
128_K	170_V	0.598	0.34
101_G	110_V	0.598	0.34
91_G	200_N	0.596	0.34
79_Q	331_S	0.596	0.34
68_T	71_I	0.594	0.34
254_A	257_K	0.591	0.34
259_A	286_M	0.590	0.33
53_G	85_E	0.589	0.33
98_A	227_A	0.589	0.33
56_L	298_V	0.587	0.33
56_L	295_A	0.585	0.33
213_D	220_E	0.584	0.33
308_L	327_R	0.583	0.33
281_D	327_R	0.583	0.33
130_I	163_F	0.581	0.33
110_V	117_T	0.580	0.33
96_I	126_T	0.580	0.33
89_F	135_E	0.579	0.33
148_T	154_G	0.578	0.33
129_M	159_I	0.578	0.33
201_P	255_V	0.578	0.33
313_A	339_V	0.577	0.32
57_T	297_A	0.575	0.32
227_A	266_K	0.575	0.32
296_L	328_L	0.574	0.32
42_P	45_R	0.571	0.32
240_C	257_K	0.571	0.32
309_S	339_V	0.569	0.32
26_N	183_F	0.566	0.32
123_N	328_L	0.566	0.32
299_T	303_C	0.565	0.31
67_Y	111_K	0.565	0.31
314_I	347_V	0.563	0.31
76_T	123_N	0.562	0.31
149_I	349_T	0.560	0.31
13_T	39_M	0.558	0.31
31_W	62_I	0.558	0.31
34_F	90_K	0.557	0.31
46_Q	55_S	0.557	0.31
254_A	289_M	0.556	0.31
102_P	145_G	0.556	0.31
99_A	155_S	0.555	0.31
230_E	330_H	0.554	0.31
99_A	103_F	0.553	0.31
54_N	128_K	0.552	0.30
237_A	245_R	0.552	0.30
128_K	332_S	0.552	0.30
41_S	46_Q	0.551	0.30
7_T	103_F	0.551	0.30
130_I	288_S	0.550	0.30
284_I	288_S	0.549	0.30
139_G	145_G	0.549	0.30
264_P	283_H	0.548	0.30
193_V	239_K	0.548	0.30
297_A	302_I	0.547	0.30
97_S	352_R	0.546	0.30
111_K	220_E	0.544	0.30
166_A	198_Y	0.544	0.30
9_M	99_A	0.541	0.30
27_N	342_T	0.540	0.30
113_K	117_T	0.539	0.29
88_D	259_A	0.539	0.29
8_I	15_K	0.538	0.29
16_G	24_M	0.538	0.29
123_N	128_K	0.538	0.29
16_G	289_M	0.537	0.29
19_F	76_T	0.535	0.29
227_A	231_E	0.535	0.29
107_E	144_D	0.535	0.29
194_S	306_R	0.534	0.29
169_S	242_F	0.533	0.29
24_M	34_F	0.533	0.29
150_S	156_G	0.532	0.29
177_T	236_A	0.532	0.29
234_S	290_Q	0.532	0.29
218_A	284_I	0.531	0.29
198_Y	299_T	0.531	0.29
181_S	282_L	0.531	0.29
97_S	286_M	0.531	0.29
16_G	356_G	0.527	0.29
184_L	229_F	0.526	0.29
185_D	228_Q	0.524	0.28
261_V	323_S	0.524	0.28
55_S	286_M	0.522	0.28
180_S	194_S	0.522	0.28
126_T	170_V	0.522	0.28
146_D	183_F	0.521	0.28
73_V	105_I	0.521	0.28
222_T	309_S	0.521	0.28
41_S	85_E	0.520	0.28
330_H	356_G	0.519	0.28
15_K	37_D	0.518	0.28
74_H	124_T	0.517	0.28
170_V	202_L	0.514	0.28
55_S	291_K	0.514	0.28
159_I	180_S	0.513	0.28
30_E	353_I	0.513	0.28
231_E	239_K	0.512	0.27
18_F	345_K	0.512	0.27
6_V	50_L	0.512	0.27
42_P	97_S	0.510	0.27
266_K	312_G	0.510	0.27
117_T	137_E	0.510	0.27
301_A	335_I	0.507	0.27
217_L	335_I	0.507	0.27
324_T	340_E	0.505	0.27
50_L	229_F	0.505	0.27
203_V	236_A	0.505	0.27
97_S	130_I	0.504	0.27
172_G	179_N	0.502	0.27
26_N	225_Q	0.501	0.27
191_I	232_L	0.500	0.27
199_A	350_A	0.500	0.27
100_V	327_R	0.500	0.27
263_K	272_G	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2pw0A	2	0.9809	100	0.189	Contact Map
3g7kA	3	0.9973	100	0.353	Contact Map
1w61A	2	0.8392	99.9	0.832	Contact Map
4lb0A	2	0.8283	99.7	0.872	Contact Map
4k8lA	2	0.7602	99.7	0.874	Contact Map
2otnA	2	0.7548	98.4	0.932	Contact Map
2gkeA	1	0.7221	97.6	0.943	Contact Map
3ednA	2	0.7411	97.5	0.945	Contact Map
1xubA	2	0.7003	97.4	0.946	Contact Map
4jbdA	2	0.7548	97.2	0.948	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0103 seconds.