GREMLIN Database
YLAJ - Uncharacterized lipoprotein YlaJ
UniProt: O07634 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 209 (161)
Sequences: 292 (249)
Seq/√Len: 19.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
72_D106_S3.5431.00
86_V156_V3.2411.00
104_K124_A3.2301.00
63_L111_L2.6940.98
81_L84_Y2.5590.98
131_R151_E2.4760.97
89_I124_A2.3600.96
86_V121_V2.3170.96
86_V135_M2.3160.96
15_S65_S2.1850.94
131_R154_A2.0780.92
88_G123_I2.0500.91
88_G132_L2.0270.91
79_V132_L1.9440.89
144_P151_E1.9380.89
134_E154_A1.9330.89
43_V46_T1.9050.88
89_I107_V1.8990.88
67_A70_N1.7990.85
138_E147_G1.7930.85
80_V155_I1.7590.84
140_S148_I1.7450.83
90_D125_D1.7300.83
67_A107_V1.6540.80
72_D112_K1.6340.79
121_V160_L1.6290.78
144_P147_G1.6070.77
68_E159_V1.6070.77
165_N168_I1.5780.76
129_V145_V1.5690.76
123_I128_T1.5570.75
64_V77_T1.5500.75
144_P158_R1.5280.74
86_V120_A1.5160.73
59_I80_V1.4860.72
11_T14_L1.4700.71
130_S150_D1.4590.70
12_L72_D1.4570.70
158_R161_P1.4300.69
68_E76_A1.4260.68
128_T135_M1.4200.68
147_G161_P1.3830.66
135_M148_I1.3770.66
122_V147_G1.3710.65
138_E143_H1.3710.65
78_A152_L1.3660.65
31_E69_K1.3600.65
144_P161_P1.3380.63
86_V160_L1.3190.62
146_T149_L1.2810.60
67_A110_A1.2520.58
129_V152_L1.2510.58
21_Q150_D1.2240.56
25_G30_K1.2140.56
80_V117_G1.2080.55
60_A79_V1.2040.55
8_I15_S1.1850.54
86_V123_I1.1670.53
67_A73_V1.1620.52
100_V157_G1.1590.52
79_V136_S1.1580.52
86_V128_T1.1520.52
106_S109_Q1.1180.49
138_E154_A1.1150.49
70_N162_E1.1130.49
64_V78_A1.1100.49
64_V126_P1.1060.49
108_A132_L1.0950.48
83_G119_N1.0840.47
83_G165_N1.0820.47
73_V82_G1.0790.47
143_H146_T1.0770.47
6_I15_S1.0700.46
103_I109_Q1.0700.46
58_D61_K1.0650.46
78_A81_L1.0610.46
117_G120_A1.0460.45
18_A21_Q1.0420.45
14_L110_A1.0400.44
10_L27_N1.0310.44
89_I112_K1.0270.44
89_I103_I1.0220.43
123_I167_V1.0190.43
46_T60_A1.0120.43
123_I162_E1.0100.43
111_L118_A0.9950.42
101_E104_K0.9940.42
133_R159_V0.9940.42
16_A83_G0.9930.42
22_G26_Q0.9930.42
21_Q28_V0.9710.40
121_V135_M0.9710.40
151_E161_P0.9700.40
32_S58_D0.9650.40
63_L115_R0.9650.40
37_E43_V0.9600.39
123_I160_L0.9580.39
22_G30_K0.9530.39
113_N148_I0.9510.39
120_A160_L0.9390.38
75_D90_D0.9360.38
91_V100_V0.9290.38
74_K136_S0.9130.37
104_K115_R0.9040.36
63_L104_K0.8950.36
13_I22_G0.8900.35
7_I11_T0.8880.35
128_T160_L0.8690.34
126_P144_P0.8650.34
73_V154_A0.8610.34
5_F16_A0.8610.34
78_A84_Y0.8610.34
42_H69_K0.8580.33
125_D163_V0.8570.33
58_D75_D0.8560.33
122_V161_P0.8450.33
99_K103_I0.8390.32
12_L16_A0.8360.32
14_L127_D0.8330.32
96_D151_E0.8290.32
59_I63_L0.8270.32
142_G161_P0.8270.32
62_H105_Y0.8200.31
21_Q41_I0.8190.31
28_V47_T0.8180.31
18_A25_G0.8170.31
92_D110_A0.8130.31
84_Y121_V0.8080.31
142_G158_R0.8030.30
42_H46_T0.7980.30
23_K143_H0.7960.30
5_F8_I0.7870.29
64_V135_M0.7860.29
138_E146_T0.7840.29
11_T65_S0.7780.29
6_I10_L0.7760.29
150_D154_A0.7730.29
111_L117_G0.7660.28
138_E159_V0.7630.28
112_K162_E0.7610.28
70_N141_E0.7550.28
70_N138_E0.7530.28
121_V133_R0.7520.28
4_L11_T0.7510.28
16_A20_Q0.7460.27
82_G155_I0.7430.27
152_L160_L0.7430.27
78_A123_I0.7430.27
66_V152_L0.7430.27
130_S154_A0.7420.27
38_T41_I0.7400.27
52_D148_I0.7320.27
111_L120_A0.7310.27
10_L16_A0.7300.27
58_D65_S0.7240.26
102_T105_Y0.7210.26
107_V160_L0.7200.26
63_L132_L0.7190.26
64_V128_T0.7060.25
86_V125_D0.7040.25
100_V105_Y0.6990.25
9_Q65_S0.6990.25
88_G106_S0.6990.25
4_L22_G0.6990.25
77_T112_K0.6980.25
70_N145_V0.6970.25
32_S41_I0.6910.25
12_L94_T0.6850.24
105_Y125_D0.6840.24
60_A138_E0.6810.24
43_V47_T0.6790.24
5_F39_K0.6760.24
9_Q146_T0.6710.24
22_G65_S0.6680.24
96_D139_I0.6640.23
61_K119_N0.6630.23
91_V96_D0.6610.23
151_E158_R0.6610.23
57_T135_M0.6610.23
76_A139_I0.6590.23
13_I32_S0.6580.23
122_V158_R0.6580.23
135_M160_L0.6570.23
20_Q162_E0.6570.23
22_G116_Y0.6450.22
82_G104_K0.6380.22
4_L7_I0.6360.22
59_I162_E0.6360.22
97_R105_Y0.6280.22
87_V119_N0.6270.22
55_T61_K0.6260.22
122_V140_S0.6240.22
78_A148_I0.6210.21
83_G146_T0.6170.21
26_Q150_D0.6130.21
66_V120_A0.6130.21
83_G118_A0.6120.21
126_P141_E0.6100.21
82_G117_G0.6050.21
104_K142_G0.5990.20
22_G29_E0.5990.20
19_Y65_S0.5960.20
56_R110_A0.5950.20
70_N119_N0.5840.20
14_L25_G0.5800.20
78_A126_P0.5770.20
5_F24_Q0.5750.19
7_I10_L0.5740.19
24_Q38_T0.5720.19
134_E138_E0.5710.19
131_R161_P0.5690.19
127_D158_R0.5690.19
154_A163_V0.5680.19
88_G125_D0.5660.19
72_D92_D0.5620.19
70_N168_I0.5620.19
9_Q113_N0.5610.19
121_V128_T0.5590.19
163_V166_D0.5560.19
140_S147_G0.5560.19
15_S167_V0.5530.19
23_K30_K0.5520.19
149_L159_V0.5510.19
43_V67_A0.5490.18
124_A131_R0.5460.18
23_K94_T0.5440.18
157_G164_P0.5430.18
57_T64_V0.5410.18
57_T131_R0.5400.18
66_V117_G0.5360.18
72_D126_P0.5340.18
53_N79_V0.5320.18
86_V95_L0.5270.18
11_T23_K0.5230.17
79_V100_V0.5210.17
55_T84_Y0.5190.17
60_A64_V0.5170.17
11_T32_S0.5140.17
97_R107_V0.5120.17
8_I61_K0.5080.17
20_Q167_V0.5010.17
116_Y160_L0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zbiC 1 0.134 70.2 0.935 Contact Map
4q2lA 1 0.3062 61.1 0.938 Contact Map
2ru9A 1 0.3349 38.9 0.946 Contact Map
3ne5A 3 0.9617 31.1 0.949 Contact Map
2jliA 1 0.4593 29.5 0.949 Contact Map
4mt1A 3 0.7703 28.3 0.95 Contact Map
4pj0U 1 0.4354 26.4 0.95 Contact Map
3ucpA 1 0.5502 26.3 0.95 Contact Map
3pmqA 1 0.4689 24.2 0.951 Contact Map
2qgmA 1 0.7033 20.3 0.953 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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