TYPA - BACSU - GREMLIN Contacts

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TYPA - GTP-binding protein TypA/BipA homolog

UniProt:	O07631	Sequences: MKLRNDLRNIAIIAHVDHGKTTLVDQLLHQAGTFRANEQVAERAMDSNDLERERGITILAKNTAINYKDTRINILDTPGHADFGGEVERIMKMVDGVVLVVDAYEGCMPQTRFVLKKALEQNLNPVVVVNKIDRDFARPEEVIDEVLDLFIELDANEEQLEFPVVYASAINGTASLDPKQQDENMEALYETIIKHVPAPVDNAEEPLQFQVALLDYNDYVGRIGIGRVFRGTMKVGQQVSLMKLDGTAKSFRVTKIFGFQGLKRVEIEEAKAGDLVAVSGMEDINVGETVCPVDHQDPLPVLRIDEPTLQMTFVVNNSPFAGREGKYVTARKIEERLQSQLQTDVSLRVEPTASPDAWVVSGRGELHLSILIENMRREGYELQVSKPEVIIKEIDGVRCEPVERVQIDVPEEHTGSVMESMGARKGEMVDMINNGNGQVRLIFTVPSRGLIGYSTEFLSLTRGFGILNHTFDSYQPMQAGQVGGRRQGVLVSMENGKATSYGIQGIEDRGVIFVEPGTEVYEGMIVGEHNRDNDLVVNVSKMKQQTNVRSATKDQTTTIKKARIMSLEESLEYLNEDEYCEVTPESIRLRKKILNKNEREKAAKKKKTAGLS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	612 (542)
Sequences:	6602 (2833)
Seq/√Len:	121.7

ECOLI - TYPA LEPA EFG RF3
BACSU - TYPA LEPA EFG
HALSA - EF2
SULSO - EF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
270_A	276_V	5.470	1.00
138_R	141_E	4.895	1.00
208_Q	230_R	4.331	1.00
444_T	472_D	4.253	1.00
234_K	269_E	4.158	1.00
167_A	188_L	3.906	1.00
128_V	167_A	3.690	1.00
232_T	269_E	3.623	1.00
165_V	191_T	3.547	1.00
444_T	475_Q	3.521	1.00
237_Q	292_P	3.356	1.00
402_V	475_Q	3.237	1.00
255_K	266_E	3.211	1.00
421_M	426_G	3.174	1.00
404_R	472_D	3.128	1.00
202_N	205_E	3.095	1.00
404_R	442_I	3.064	1.00
191_T	195_H	2.996	1.00
238_Q	250_S	2.982	1.00
376_R	381_E	2.945	1.00
190_E	194_K	2.868	1.00
394_I	399_C	2.828	1.00
409_V	417_V	2.815	1.00
258_G	267_I	2.807	1.00
143_I	164_V	2.769	1.00
478_Q	500_S	2.521	1.00
550_S	553_K	2.475	1.00
430_D	442_I	2.441	1.00
35_R	38_E	2.424	1.00
30_Q	186_E	2.407	1.00
420_S	453_Y	2.402	1.00
427_E	475_Q	2.372	1.00
104_Y	134_R	2.332	1.00
457_F	465_G	2.323	1.00
26_Q	29_H	2.317	1.00
205_E	230_R	2.310	1.00
34_F	44_A	2.294	1.00
405_V	467_L	2.290	1.00
66_N	69_D	2.285	1.00
429_V	444_T	2.277	1.00
461_T	465_G	2.272	1.00
404_R	470_T	2.232	1.00
132_I	173_T	2.226	1.00
215_D	225_I	2.225	1.00
420_S	460_L	2.218	1.00
444_T	473_S	2.210	1.00
240_S	250_S	2.209	1.00
279_S	282_E	2.139	1.00
96_G	196_V	2.137	1.00
498_A	514_V	2.040	1.00
154_D	157_E	2.037	1.00
70_T	193_I	2.000	1.00
414_T	439_V	1.990	1.00
239_V	253_V	1.966	1.00
240_S	248_A	1.962	1.00
232_T	271_K	1.962	1.00
235_V	256_I	1.948	1.00
411_E	439_V	1.914	1.00
224_G	284_I	1.901	1.00
306_E	348_R	1.884	1.00
243_K	247_T	1.868	1.00
235_V	268_E	1.860	1.00
497_K	519_E	1.847	1.00
207_L	239_V	1.840	1.00
50_L	58_I	1.833	1.00
529_H	535_L	1.833	1.00
67_Y	190_E	1.820	1.00
249_K	283_D	1.805	1.00
565_M	569_E	1.794	1.00
228_V	270_A	1.791	1.00
427_E	444_T	1.790	1.00
143_I	166_Y	1.772	1.00
230_R	297_D	1.772	1.00
334_E	351_P	1.759	1.00
75_L	94_V	1.759	1.00
233_M	253_V	1.745	1.00
30_Q	185_M	1.717	1.00
10_I	72_I	1.716	1.00
548_V	551_A	1.712	1.00
144_D	148_D	1.708	1.00
350_E	361_S	1.707	1.00
27_L	185_M	1.683	1.00
64_A	71_R	1.679	1.00
234_K	237_Q	1.676	1.00
223_I	277_A	1.667	1.00
267_I	270_A	1.644	1.00
6_D	70_T	1.640	1.00
526_V	539_V	1.637	1.00
12_I	24_V	1.637	1.00
203_A	272_A	1.629	1.00
373_E	377_R	1.626	1.00
511_V	563_R	1.623	1.00
405_V	445_V	1.616	1.00
404_R	444_T	1.608	1.00
347_L	371_L	1.605	1.00
419_E	423_A	1.604	1.00
334_E	338_Q	1.603	1.00
426_G	445_V	1.601	1.00
498_A	518_T	1.596	1.00
525_I	548_V	1.593	1.00
9_N	73_N	1.572	1.00
98_V	128_V	1.564	1.00
238_Q	252_R	1.558	1.00
515_E	564_I	1.556	1.00
409_V	465_G	1.547	1.00
207_L	228_V	1.544	1.00
515_E	518_T	1.537	1.00
138_R	142_V	1.530	1.00
112_R	464_F	1.509	1.00
395_D	399_C	1.507	1.00
186_E	190_E	1.502	1.00
329_T	332_K	1.501	1.00
551_A	556_T	1.498	1.00
27_L	65_I	1.492	1.00
556_T	561_K	1.491	1.00
228_V	276_V	1.481	1.00
341_L	347_L	1.475	1.00
408_D	440_R	1.472	1.00
527_G	546_T	1.468	1.00
338_Q	351_P	1.449	1.00
50_L	370_I	1.446	1.00
350_E	359_V	1.442	1.00
310_Q	361_S	1.439	1.00
420_S	456_E	1.437	1.00
407_I	421_M	1.436	1.00
48_N	59_L	1.430	1.00
97_V	123_L	1.427	1.00
406_Q	442_I	1.424	1.00
316_N	381_E	1.420	1.00
251_F	281_M	1.409	1.00
6_D	69_D	1.393	1.00
23_L	100_V	1.386	1.00
411_E	437_G	1.385	1.00
38_E	263_K	1.383	1.00
472_D	475_Q	1.382	1.00
417_V	461_T	1.380	1.00
418_M	441_L	1.380	1.00
150_F	154_D	1.374	1.00
68_K	190_E	1.370	1.00
129_V	166_Y	1.357	1.00
314_V	383_Q	1.349	1.00
336_R	375_M	1.339	1.00
410_P	464_F	1.338	1.00
11_A	94_V	1.328	1.00
504_Q	507_E	1.327	1.00
391_I	398_R	1.320	1.00
126_V	191_T	1.320	1.00
482_V	498_A	1.319	1.00
507_E	511_V	1.319	1.00
201_D	230_R	1.317	1.00
141_E	145_E	1.316	1.00
50_L	374_N	1.309	1.00
147_L	153_L	1.300	1.00
47_S	61_K	1.298	1.00
393_E	398_R	1.296	1.00
391_I	474_Y	1.293	1.00
406_Q	440_R	1.291	1.00
130_N	169_A	1.286	1.00
45_M	63_T	1.286	1.00
13_I	99_L	1.282	1.00
491_V	536_V	1.278	1.00
513_F	523_G	1.277	1.00
456_E	460_L	1.273	1.00
211_V	224_G	1.272	1.00
49_D	377_R	1.272	1.00
104_Y	136_F	1.270	1.00
41_A	52_R	1.269	1.00
96_G	197_P	1.267	1.00
139_P	142_V	1.266	1.00
203_A	271_K	1.265	1.00
184_N	187_A	1.265	1.00
553_K	556_T	1.262	1.00
34_F	37_N	1.262	1.00
173_T	185_M	1.261	1.00
260_Q	265_V	1.260	1.00
33_T	65_I	1.248	0.99
405_V	450_L	1.247	0.99
391_I	448_R	1.235	0.99
372_I	384_V	1.231	0.99
292_P	295_H	1.227	0.99
207_L	233_M	1.222	0.99
6_D	68_K	1.219	0.99
433_N	439_V	1.219	0.99
233_M	278_V	1.218	0.99
242_M	291_C	1.214	0.99
498_A	515_E	1.211	0.99
407_I	417_V	1.209	0.99
404_R	429_V	1.206	0.99
507_E	560_K	1.203	0.99
129_V	143_I	1.197	0.99
555_Q	558_T	1.195	0.99
103_A	129_V	1.190	0.99
222_R	342_Q	1.190	0.99
423_A	456_E	1.187	0.99
66_N	260_Q	1.185	0.99
271_K	274_D	1.185	0.99
235_V	266_E	1.184	0.99
23_L	188_L	1.183	0.99
529_H	547_N	1.182	0.99
66_N	71_R	1.182	0.99
202_N	206_P	1.182	0.99
347_L	360_V	1.181	0.99
402_V	479_A	1.181	0.99
30_Q	172_G	1.180	0.99
365_E	452_G	1.180	0.99
402_V	472_D	1.171	0.99
250_S	293_V	1.166	0.99
11_A	91_M	1.165	0.99
209_F	226_G	1.164	0.99
163_P	195_H	1.164	0.99
270_A	274_D	1.151	0.99
207_L	232_T	1.148	0.99
34_F	40_V	1.146	0.99
203_A	232_T	1.146	0.99
453_Y	460_L	1.146	0.99
471_F	474_Y	1.144	0.99
310_Q	359_V	1.134	0.99
316_N	383_Q	1.127	0.99
28_L	33_T	1.122	0.99
421_M	445_V	1.108	0.99
115_L	119_L	1.099	0.99
403_E	450_L	1.099	0.99
226_G	278_V	1.090	0.99
150_F	153_L	1.086	0.99
480_G	484_G	1.085	0.99
281_M	284_I	1.083	0.99
10_I	192_I	1.082	0.98
171_N	185_M	1.082	0.98
24_V	45_M	1.081	0.98
28_L	44_A	1.079	0.98
405_V	469_H	1.078	0.98
24_V	74_I	1.077	0.98
241_L	284_I	1.075	0.98
235_V	254_T	1.067	0.98
333_I	380_Y	1.064	0.98
556_T	564_I	1.060	0.98
208_Q	299_L	1.059	0.98
71_R	274_D	1.058	0.98
428_M	431_M	1.057	0.98
65_I	74_I	1.056	0.98
34_F	38_E	1.055	0.98
508_D	512_I	1.054	0.98
31_A	189_Y	1.053	0.98
142_V	145_E	1.051	0.98
31_A	65_I	1.049	0.98
412_E	462_R	1.045	0.98
419_E	422_G	1.039	0.98
120_E	303_R	1.037	0.98
544_Q	548_V	1.034	0.98
407_I	457_F	1.030	0.98
8_R	199_P	1.029	0.98
431_M	439_V	1.028	0.98
29_H	36_A	1.027	0.98
233_M	256_I	1.026	0.98
184_N	188_L	1.025	0.98
570_S	574_L	1.024	0.98
411_E	436_N	1.023	0.98
534_D	539_V	1.020	0.98
228_V	233_M	1.019	0.98
40_V	44_A	1.019	0.98
403_E	447_S	1.019	0.98
416_S	460_L	1.018	0.98
394_I	397_V	1.015	0.98
243_K	288_E	1.013	0.98
255_K	277_A	1.009	0.98
402_V	473_S	1.008	0.98
126_V	196_V	1.008	0.98
548_V	556_T	1.003	0.98
49_D	53_E	0.999	0.97
60_A	75_L	0.997	0.97
563_R	569_E	0.995	0.97
150_F	156_N	0.994	0.97
405_V	421_M	0.990	0.97
560_K	563_R	0.987	0.97
566_S	569_E	0.986	0.97
13_I	97_V	0.981	0.97
504_Q	555_Q	0.976	0.97
152_E	155_A	0.976	0.97
500_S	557_T	0.975	0.97
511_V	543_K	0.972	0.97
71_R	258_G	0.971	0.97
14_A	17_D	0.970	0.97
285_N	304_I	0.969	0.97
556_T	560_K	0.967	0.97
72_I	193_I	0.966	0.97
53_E	377_R	0.964	0.97
14_A	18_H	0.963	0.97
234_K	268_E	0.961	0.97
257_F	277_A	0.958	0.97
207_L	253_V	0.955	0.97
516_P	519_E	0.952	0.97
552_T	555_Q	0.952	0.97
267_I	276_V	0.952	0.97
41_A	44_A	0.948	0.97
510_G	532_D	0.947	0.97
556_T	565_M	0.946	0.96
206_P	295_H	0.945	0.96
391_I	477_M	0.939	0.96
21_T	24_V	0.937	0.96
114_V	117_K	0.936	0.96
220_V	255_K	0.930	0.96
353_A	356_D	0.930	0.96
569_E	572_E	0.930	0.96
422_G	443_F	0.930	0.96
479_A	482_V	0.928	0.96
53_E	373_E	0.926	0.96
548_V	555_Q	0.925	0.96
346_S	371_L	0.924	0.96
241_L	290_V	0.921	0.96
291_C	296_Q	0.921	0.96
17_D	56_I	0.919	0.96
45_M	57_T	0.919	0.96
239_V	290_V	0.919	0.96
201_D	272_A	0.915	0.96
550_S	555_Q	0.914	0.96
418_M	428_M	0.913	0.96
414_T	441_L	0.909	0.96
204_E	232_T	0.906	0.95
400_E	425_K	0.897	0.95
155_A	162_F	0.895	0.95
27_L	31_A	0.894	0.95
478_Q	504_Q	0.894	0.95
396_G	476_P	0.894	0.95
338_Q	341_L	0.893	0.95
482_V	496_G	0.892	0.95
126_V	165_V	0.891	0.95
515_E	543_K	0.890	0.95
102_D	105_E	0.889	0.95
554_D	557_T	0.889	0.95
514_V	518_T	0.888	0.95
92_K	229_F	0.885	0.95
26_Q	185_M	0.881	0.95
421_M	443_F	0.881	0.95
453_Y	465_G	0.880	0.95
432_I	442_I	0.878	0.95
45_M	61_K	0.878	0.95
225_I	259_F	0.877	0.95
512_I	515_E	0.876	0.95
64_A	73_N	0.875	0.95
140_E	144_D	0.872	0.94
514_V	543_K	0.869	0.94
528_E	563_R	0.867	0.94
409_V	441_L	0.866	0.94
128_V	188_L	0.866	0.94
352_T	355_P	0.864	0.94
100_V	169_A	0.863	0.94
28_L	63_T	0.861	0.94
50_L	61_K	0.861	0.94
68_K	186_E	0.861	0.94
95_D	227_R	0.859	0.94
226_G	276_V	0.858	0.94
85_G	346_S	0.857	0.94
506_I	512_I	0.855	0.94
483_G	487_Q	0.855	0.94
445_V	450_L	0.855	0.94
499_T	504_Q	0.852	0.94
477_M	481_Q	0.852	0.94
360_V	371_L	0.851	0.94
173_T	184_N	0.851	0.94
544_Q	547_N	0.847	0.94
139_P	166_Y	0.847	0.94
344_D	367_H	0.847	0.94
553_K	557_T	0.846	0.94
555_Q	560_K	0.845	0.93
149_L	153_L	0.844	0.93
29_H	40_V	0.844	0.93
477_M	485_R	0.843	0.93
56_I	366_L	0.842	0.93
50_L	54_R	0.842	0.93
256_I	268_E	0.841	0.93
414_T	431_M	0.839	0.93
313_F	360_V	0.839	0.93
155_A	164_V	0.839	0.93
32_G	35_R	0.835	0.93
329_T	381_E	0.835	0.93
118_A	125_P	0.832	0.93
102_D	134_R	0.832	0.93
12_I	98_V	0.827	0.93
65_I	72_I	0.826	0.93
402_V	477_M	0.823	0.93
139_P	143_I	0.823	0.93
209_F	278_V	0.823	0.93
101_V	111_T	0.822	0.93
49_D	52_R	0.818	0.92
147_L	164_V	0.816	0.92
288_E	301_V	0.814	0.92
188_L	192_I	0.812	0.92
255_K	279_S	0.812	0.92
240_S	293_V	0.811	0.92
494_E	540_S	0.810	0.92
393_E	399_C	0.808	0.92
167_A	184_N	0.808	0.92
312_T	385_S	0.808	0.92
147_L	155_A	0.807	0.92
37_N	172_G	0.801	0.92
136_F	139_P	0.801	0.92
573_Y	576_E	0.799	0.91
504_Q	557_T	0.795	0.91
201_D	205_E	0.794	0.91
228_V	232_T	0.793	0.91
129_V	139_P	0.793	0.91
242_M	298_P	0.787	0.91
507_E	553_K	0.786	0.91
311_M	384_V	0.785	0.91
192_I	196_V	0.785	0.91
7_L	274_D	0.784	0.91
91_M	121_Q	0.783	0.91
152_E	157_E	0.782	0.91
375_M	382_L	0.781	0.91
155_A	163_P	0.780	0.90
312_T	357_A	0.779	0.90
453_Y	457_F	0.779	0.90
37_N	40_V	0.778	0.90
206_P	292_P	0.776	0.90
340_Q	375_M	0.776	0.90
529_H	544_Q	0.776	0.90
64_A	258_G	0.776	0.90
369_S	372_I	0.775	0.90
562_A	565_M	0.775	0.90
508_D	511_V	0.775	0.90
239_V	251_F	0.773	0.90
35_R	40_V	0.771	0.90
207_L	290_V	0.771	0.90
50_L	373_E	0.768	0.90
17_D	22_T	0.766	0.90
341_L	349_V	0.766	0.90
425_K	449_G	0.765	0.90
236_G	254_T	0.764	0.90
258_G	274_D	0.761	0.89
314_V	357_A	0.761	0.89
417_V	460_L	0.759	0.89
116_K	438_Q	0.759	0.89
489_V	525_I	0.758	0.89
238_Q	293_V	0.758	0.89
479_A	483_G	0.758	0.89
98_V	188_L	0.757	0.89
7_L	73_N	0.754	0.89
545_Q	550_S	0.752	0.89
165_V	195_H	0.752	0.89
31_A	67_Y	0.751	0.89
93_M	212_A	0.751	0.89
365_E	455_T	0.749	0.89
14_A	57_T	0.748	0.89
137_A	142_V	0.747	0.88
485_R	534_D	0.747	0.88
233_M	237_Q	0.743	0.88
402_V	444_T	0.742	0.88
556_T	562_A	0.742	0.88
331_R	335_E	0.741	0.88
202_N	232_T	0.740	0.88
499_T	542_M	0.740	0.88
373_E	376_R	0.739	0.88
81_A	113_F	0.738	0.88
504_Q	556_T	0.738	0.88
258_G	270_A	0.737	0.88
210_Q	301_V	0.736	0.88
256_I	277_A	0.735	0.88
512_I	539_V	0.733	0.88
9_N	12_I	0.733	0.88
167_A	171_N	0.732	0.87
450_L	467_L	0.731	0.87
528_E	573_Y	0.731	0.87
372_I	376_R	0.730	0.87
557_T	560_K	0.728	0.87
529_H	542_M	0.728	0.87
191_T	194_K	0.728	0.87
241_L	251_F	0.727	0.87
30_Q	167_A	0.727	0.87
486_R	530_N	0.726	0.87
157_E	163_P	0.725	0.87
215_D	428_M	0.722	0.87
493_M	506_I	0.719	0.87
506_I	539_V	0.718	0.86
128_V	169_A	0.718	0.86
59_L	63_T	0.717	0.86
509_R	512_I	0.714	0.86
413_H	464_F	0.714	0.86
103_A	137_A	0.710	0.86
564_I	569_E	0.710	0.86
54_R	369_S	0.709	0.86
505_G	508_D	0.709	0.86
411_E	414_T	0.709	0.86
209_F	228_V	0.709	0.86
146_V	153_L	0.707	0.86
48_N	377_R	0.707	0.86
397_V	476_P	0.705	0.85
102_D	131_K	0.703	0.85
223_I	264_R	0.702	0.85
551_A	560_K	0.701	0.85
555_Q	561_K	0.701	0.85
15_H	18_H	0.700	0.85
549_R	568_E	0.697	0.85
500_S	504_Q	0.695	0.85
27_L	189_Y	0.694	0.85
338_Q	349_V	0.693	0.84
306_E	468_N	0.693	0.84
326_K	329_T	0.692	0.84
208_Q	296_Q	0.691	0.84
335_E	338_Q	0.691	0.84
561_K	565_M	0.691	0.84
103_A	132_I	0.691	0.84
205_E	297_D	0.690	0.84
514_V	530_N	0.690	0.84
557_T	561_K	0.690	0.84
405_V	443_F	0.687	0.84
264_R	277_A	0.687	0.84
13_I	91_M	0.686	0.84
121_Q	229_F	0.684	0.84
235_V	255_K	0.683	0.84
429_V	472_D	0.683	0.84
216_Y	342_Q	0.682	0.84
90_I	94_V	0.682	0.84
530_N	545_Q	0.678	0.83
147_L	150_F	0.677	0.83
566_S	574_L	0.676	0.83
28_L	34_F	0.676	0.83
44_A	263_K	0.676	0.83
23_L	185_M	0.676	0.83
209_F	233_M	0.674	0.83
80_H	89_R	0.673	0.83
413_H	462_R	0.672	0.83
291_C	295_H	0.671	0.83
101_V	142_V	0.670	0.82
424_R	456_E	0.669	0.82
504_Q	554_D	0.668	0.82
205_E	208_Q	0.666	0.82
77_T	87_V	0.664	0.82
99_L	114_V	0.664	0.82
68_K	189_Y	0.663	0.82
359_V	388_E	0.661	0.82
327_Y	332_K	0.660	0.81
432_I	440_R	0.660	0.81
489_V	573_Y	0.659	0.81
150_F	157_E	0.657	0.81
410_P	413_H	0.657	0.81
167_A	173_T	0.656	0.81
524_M	528_E	0.655	0.81
144_D	147_L	0.655	0.81
222_R	284_I	0.653	0.81
48_N	58_I	0.653	0.81
64_A	274_D	0.653	0.81
309_L	451_I	0.652	0.81
569_E	573_Y	0.651	0.81
308_T	403_E	0.651	0.81
403_E	445_V	0.651	0.81
332_K	335_E	0.650	0.80
202_N	272_A	0.646	0.80
520_V	524_M	0.646	0.80
511_V	541_K	0.646	0.80
428_M	443_F	0.645	0.80
149_L	164_V	0.645	0.80
56_I	80_H	0.645	0.80
60_A	215_D	0.643	0.80
17_D	57_T	0.643	0.80
108_M	134_R	0.643	0.80
529_H	532_D	0.642	0.80
327_Y	380_Y	0.642	0.80
165_V	184_N	0.641	0.80
511_V	515_E	0.641	0.80
169_A	184_N	0.641	0.80
22_T	169_A	0.640	0.79
395_D	398_R	0.640	0.79
10_I	21_T	0.640	0.79
414_T	418_M	0.640	0.79
558_T	564_I	0.637	0.79
424_R	452_G	0.637	0.79
27_L	30_Q	0.636	0.79
571_L	575_N	0.634	0.79
189_Y	193_I	0.632	0.79
556_T	573_Y	0.632	0.79
394_I	476_P	0.632	0.79
15_H	111_T	0.631	0.79
403_E	469_H	0.631	0.79
208_Q	229_F	0.631	0.79
27_L	72_I	0.631	0.79
26_Q	172_G	0.630	0.78
119_L	150_F	0.630	0.78
525_I	575_N	0.628	0.78
311_M	368_L	0.628	0.78
542_M	545_Q	0.628	0.78
535_L	539_V	0.627	0.78
138_R	145_E	0.627	0.78
565_M	573_Y	0.626	0.78
146_V	150_F	0.626	0.78
84_G	305_D	0.623	0.78
137_A	141_E	0.623	0.78
535_L	548_V	0.622	0.78
17_D	131_K	0.622	0.78
266_E	277_A	0.618	0.77
499_T	540_S	0.618	0.77
452_G	456_E	0.618	0.77
492_S	499_T	0.618	0.77
552_T	556_T	0.618	0.77
241_L	249_K	0.617	0.77
552_T	558_T	0.616	0.77
146_V	164_V	0.615	0.77
251_F	284_I	0.613	0.76
548_V	553_K	0.613	0.76
13_I	118_A	0.612	0.76
11_A	65_I	0.611	0.76
340_Q	344_D	0.611	0.76
557_T	566_S	0.610	0.76
544_Q	550_S	0.609	0.76
233_M	239_V	0.609	0.76
170_I	185_M	0.609	0.76
224_G	280_G	0.608	0.76
508_D	530_N	0.608	0.76
554_D	560_K	0.607	0.76
25_D	43_R	0.607	0.76
542_M	551_A	0.606	0.76
256_I	278_V	0.606	0.76
332_K	336_R	0.605	0.76
372_I	383_Q	0.605	0.76
510_G	534_D	0.604	0.75
84_G	117_K	0.604	0.75
52_R	55_G	0.604	0.75
330_A	334_E	0.604	0.75
11_A	192_I	0.604	0.75
220_V	264_R	0.603	0.75
48_N	374_N	0.601	0.75
140_E	166_Y	0.600	0.75
548_V	554_D	0.600	0.75
566_S	570_S	0.599	0.75
514_V	539_V	0.598	0.75
299_L	302_L	0.598	0.75
557_T	562_A	0.597	0.75
560_K	575_N	0.597	0.75
553_K	565_M	0.596	0.74
563_R	574_L	0.596	0.74
403_E	467_L	0.596	0.74
386_K	452_G	0.595	0.74
240_S	296_Q	0.594	0.74
518_T	524_M	0.594	0.74
150_F	155_A	0.593	0.74
515_E	562_A	0.593	0.74
493_M	542_M	0.593	0.74
563_R	566_S	0.592	0.74
11_A	97_V	0.591	0.74
30_Q	184_N	0.591	0.74
240_S	291_C	0.590	0.74
352_T	357_A	0.590	0.74
99_L	127_V	0.590	0.74
30_Q	189_Y	0.589	0.74
257_F	266_E	0.587	0.73
115_L	149_L	0.586	0.73
110_Q	113_F	0.585	0.73
433_N	437_G	0.584	0.73
189_Y	192_I	0.584	0.73
56_I	131_K	0.584	0.73
8_R	12_I	0.583	0.73
496_G	509_R	0.582	0.73
550_S	554_D	0.582	0.73
524_M	529_H	0.581	0.73
34_F	169_A	0.581	0.73
561_K	564_I	0.581	0.73
507_E	515_E	0.580	0.72
330_A	358_W	0.579	0.72
52_R	262_L	0.578	0.72
571_L	574_L	0.578	0.72
552_T	557_T	0.578	0.72
260_Q	263_K	0.577	0.72
530_N	546_T	0.576	0.72
225_I	428_M	0.575	0.72
22_T	170_I	0.575	0.72
92_K	302_L	0.574	0.72
30_Q	187_A	0.574	0.72
98_V	126_V	0.574	0.72
119_L	125_P	0.572	0.71
426_G	443_F	0.572	0.71
547_N	551_A	0.571	0.71
101_V	107_C	0.571	0.71
27_L	98_V	0.570	0.71
100_V	130_N	0.570	0.71
98_V	165_V	0.570	0.71
56_I	86_E	0.569	0.71
542_M	556_T	0.569	0.71
490_L	510_G	0.569	0.71
26_Q	30_Q	0.568	0.71
334_E	358_W	0.567	0.71
543_K	546_T	0.566	0.71
115_L	125_P	0.566	0.71
7_L	71_R	0.565	0.71
347_L	367_H	0.565	0.71
447_S	469_H	0.565	0.71
557_T	570_S	0.564	0.70
372_I	382_L	0.564	0.70
554_D	561_K	0.564	0.70
362_G	387_P	0.563	0.70
116_K	120_E	0.563	0.70
553_K	562_A	0.563	0.70
127_V	162_F	0.562	0.70
560_K	567_L	0.561	0.70
72_I	189_Y	0.560	0.70
560_K	569_E	0.559	0.70
504_Q	558_T	0.559	0.70
392_K	474_Y	0.557	0.69
217_N	223_I	0.557	0.69
525_I	547_N	0.557	0.69
57_T	77_T	0.557	0.69
393_E	396_G	0.556	0.69
496_G	510_G	0.556	0.69
16_V	57_T	0.555	0.69
198_A	201_D	0.555	0.69
419_E	460_L	0.554	0.69
81_A	110_Q	0.553	0.69
538_N	553_K	0.553	0.69
17_D	20_K	0.553	0.69
75_L	93_M	0.553	0.69
308_T	311_M	0.553	0.69
36_A	40_V	0.550	0.69
208_Q	297_D	0.550	0.69
499_T	556_T	0.550	0.69
434_N	440_R	0.549	0.68
226_G	233_M	0.549	0.68
413_H	416_S	0.549	0.68
18_H	118_A	0.548	0.68
553_K	564_I	0.547	0.68
16_V	56_I	0.547	0.68
513_F	528_E	0.547	0.68
414_T	428_M	0.546	0.68
105_E	134_R	0.546	0.68
101_V	146_V	0.545	0.68
536_V	558_T	0.545	0.68
541_K	544_Q	0.545	0.68
225_I	277_A	0.544	0.68
82_D	87_V	0.544	0.68
47_S	263_K	0.544	0.68
48_N	53_E	0.543	0.68
545_Q	548_V	0.542	0.67
555_Q	562_A	0.542	0.67
507_E	557_T	0.541	0.67
542_M	548_V	0.540	0.67
565_M	570_S	0.540	0.67
17_D	110_Q	0.540	0.67
314_V	385_S	0.540	0.67
16_V	80_H	0.537	0.67
114_V	118_A	0.537	0.67
149_L	152_E	0.537	0.67
17_D	80_H	0.537	0.67
505_G	512_I	0.536	0.67
148_D	157_E	0.536	0.67
488_G	527_G	0.535	0.66
417_V	457_F	0.534	0.66
564_I	575_N	0.534	0.66
534_D	538_N	0.530	0.66
87_V	114_V	0.529	0.66
542_M	557_T	0.528	0.65
494_E	522_E	0.528	0.65
237_Q	253_V	0.527	0.65
555_Q	559_I	0.527	0.65
133_D	168_S	0.527	0.65
506_I	535_L	0.526	0.65
149_L	154_D	0.524	0.65
148_D	153_L	0.524	0.65
243_K	283_D	0.524	0.65
72_I	192_I	0.523	0.65
105_E	108_M	0.523	0.65
157_E	195_H	0.523	0.65
311_M	360_V	0.523	0.65
92_K	121_Q	0.522	0.65
527_G	545_Q	0.522	0.65
568_E	571_L	0.522	0.65
13_I	126_V	0.521	0.64
560_K	564_I	0.521	0.64
119_L	122_N	0.521	0.64
56_I	82_D	0.520	0.64
357_A	385_S	0.519	0.64
110_Q	114_V	0.518	0.64
54_R	58_I	0.517	0.64
512_I	525_I	0.517	0.64
143_I	146_V	0.517	0.64
81_A	308_T	0.517	0.64
165_V	188_L	0.516	0.64
514_V	562_A	0.516	0.64
352_T	356_D	0.515	0.63
522_E	536_V	0.514	0.63
29_H	172_G	0.514	0.63
552_T	560_K	0.513	0.63
31_A	34_F	0.513	0.63
33_T	44_A	0.512	0.63
229_F	299_L	0.511	0.63
525_I	577_D	0.511	0.63
548_V	570_S	0.511	0.63
157_E	162_F	0.511	0.63
551_A	558_T	0.511	0.63
8_R	197_P	0.510	0.63
407_I	465_G	0.510	0.63
108_M	367_H	0.510	0.63
500_S	506_I	0.509	0.63
62_N	259_F	0.508	0.62
17_D	55_G	0.508	0.62
511_V	544_Q	0.508	0.62
94_V	275_L	0.508	0.62
418_M	431_M	0.507	0.62
536_V	569_E	0.506	0.62
507_E	510_G	0.506	0.62
558_T	563_R	0.505	0.62
352_T	359_V	0.505	0.62
425_K	448_R	0.505	0.62
107_C	149_L	0.505	0.62
405_V	426_G	0.504	0.62
415_G	419_E	0.504	0.62
169_A	173_T	0.504	0.62
258_G	276_V	0.503	0.62
33_T	260_Q	0.503	0.62
552_T	563_R	0.503	0.62
255_K	267_I	0.503	0.62
129_V	451_I	0.502	0.62
500_S	516_P	0.502	0.62
493_M	539_V	0.502	0.62
524_M	527_G	0.502	0.62
43_R	52_R	0.500	0.61
568_E	574_L	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4zciA	1	0.9134	100	0.234	Contact Map
2yweA	1	0.7974	100	0.301	Contact Map
3cb4D	1	0.7958	100	0.308	Contact Map
4qjty	1	0.8742	100	0.318	Contact Map
4kiyV	1	0.7451	100	0.415	Contact Map
2xexA	1	0.7435	100	0.421	Contact Map
1darA	1	0.6405	100	0.421	Contact Map
1n0uA	1	0.7843	100	0.422	Contact Map
4w224	1	0.8186	100	0.422	Contact Map
3j25A	1	0.7729	100	0.425	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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