YHFT - BACSU - GREMLIN Contacts

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YHFT - Uncharacterized acyl--CoA ligase YhfT

UniProt:	O07619	Sequences: MTITHTYSSTAETSPGRVAIQTESEQITYHDWDRLVSQTANWLRSQPSMPNRVAILLPNSLAFLQLFAGAAAAGCTAIPIDTRWSPAECKERLSISNADLVVTLAFFKNKLTDSQTPVVLLDNCMADISEAAADPLPTIDPEHPFYMGFTSGSTGKPKAFTRSHRSWMESFTCTETDFSISSDDKVLIPGALMSSHFLYGAVSTLFLGGTVCLLKKFSPAKAKEWLCRESISVLYTVPTMTDALARIEGFPDSPVKIISSGADWPAESKKKLAAAWPHLKLYDFYGTSELSFVTFSSPEDSKRKPHSAGRPFHNVRIEIRNAGGERCQPGEIGKIFVKSPMRFSGYVNGSTPDEWMTVDDMGYVDEEGFLYISGRENGMIVYGGLNIFPEEIERVLLACPEVESAAVVGIPDEYWGEIAVAVILGNANARTLKAWCKQKLASYKIPKKWVFADSLPETSSGKIARSRVKKWLEESVQYK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	479 (463)
Sequences:	71914 (51954)
Seq/√Len:	2414.5

ECOLI - AAS ENTF ACSA LCFA PRPE ENTE CAIC FADK MENE PAAK
BACSU - YHFT SRFAC PPSE LCFA LCFB ACSA YNGI DHBE YDAB MENE PPSB PPSC DLTA YTCI DHBF PKSJ PPSD PKSN SRFAA PPSA SRFAB
HALSA - Q9HSM3 Q9HRY8 Q9HQU8 Q9HQN8 Q9HQ43 Q9HNK0
SULSO - Q97UX8 Q97UW7 Q97VT6 Q97U22 Q97WQ0 Q97VU7 Q97YK9 Q97V27 Q97XW4 Q97WQ9 Q97WK0 Q97UF6 Q980E4 Q97WS5 Q97X52 Q97XW5 Q97VJ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
144_P	161_T	3.899	1.00
399_C	435_W	3.207	1.00
335_I	362_G	3.087	1.00
37_S	72_A	2.976	1.00
316_R	338_K	2.922	1.00
54_A	98_A	2.823	1.00
51_N	99_D	2.810	1.00
95_I	149_F	2.803	1.00
163_S	344_S	2.793	1.00
363_Y	371_Y	2.763	1.00
33_D	72_A	2.752	1.00
21_Q	210_T	2.647	1.00
334_K	357_T	2.570	1.00
48_S	75_C	2.529	1.00
185_K	210_T	2.458	1.00
381_V	386_N	2.421	1.00
18_V	26_Q	2.397	1.00
404_S	457_E	2.383	1.00
97_N	348_N	2.367	1.00
42_W	46_Q	2.356	1.00
397_L	405_A	2.332	1.00
14_S	17_R	2.329	1.00
8_S	33_D	2.313	1.00
318_E	326_R	2.309	1.00
52_R	78_I	2.288	1.00
35_L	65_Q	2.281	1.00
320_R	336_F	2.258	1.00
336_F	357_T	2.255	1.00
321_N	325_E	2.243	1.00
95_I	349_G	2.197	1.00
91_E	156_K	2.190	1.00
10_T	14_S	2.175	1.00
332_I	361_M	2.173	1.00
365_D	371_Y	2.162	1.00
33_D	37_S	2.141	1.00
464_A	467_R	2.126	1.00
66_L	102_V	2.126	1.00
378_G	465_R	2.082	1.00
70_A	75_C	2.065	1.00
396_L	421_A	2.052	1.00
420_V	450_V	2.043	1.00
224_E	228_R	2.042	1.00
22_T	61_L	2.031	1.00
184_D	256_K	1.988	1.00
363_Y	373_S	1.978	1.00
398_A	439_K	1.966	1.00
140_D	143_H	1.966	1.00
266_A	270_K	1.922	1.00
365_D	369_F	1.906	1.00
21_Q	26_Q	1.903	1.00
39_T	65_Q	1.886	1.00
318_E	336_F	1.884	1.00
184_D	232_S	1.881	1.00
90_K	94_S	1.842	1.00
307_S	371_Y	1.837	1.00
16_G	30_H	1.832	1.00
391_E	444_K	1.802	1.00
44_R	73_A	1.787	1.00
467_R	470_K	1.778	1.00
21_Q	229_E	1.749	1.00
36_V	72_A	1.742	1.00
364_V	370_L	1.734	1.00
30_H	34_R	1.702	1.00
9_S	13_T	1.696	1.00
332_I	373_S	1.693	1.00
393_E	407_V	1.685	1.00
397_L	404_S	1.682	1.00
212_C	231_I	1.650	1.00
64_L	201_A	1.648	1.00
28_T	31_D	1.646	1.00
163_S	166_S	1.644	1.00
230_S	254_P	1.642	1.00
382_Y	387_I	1.626	1.00
329_P	364_V	1.611	1.00
408_V	422_V	1.604	1.00
144_P	344_S	1.593	1.00
54_A	80_I	1.590	1.00
52_R	76_T	1.582	1.00
423_I	451_F	1.580	1.00
58_P	104_L	1.563	1.00
71_A	145_F	1.558	1.00
149_F	159_A	1.554	1.00
175_E	207_L	1.548	1.00
27_I	65_Q	1.535	1.00
10_T	13_T	1.531	1.00
422_V	468_V	1.530	1.00
236_T	241_T	1.526	1.00
15_P	30_H	1.524	1.00
424_L	455_L	1.521	1.00
221_K	224_E	1.513	1.00
280_K	298_P	1.505	1.00
435_W	439_K	1.503	1.00
428_N	431_T	1.503	1.00
37_S	41_N	1.501	1.00
401_E	431_T	1.501	1.00
8_S	72_A	1.499	1.00
294_T	337_V	1.488	1.00
319_I	362_G	1.482	1.00
53_V	70_A	1.475	1.00
407_V	421_A	1.474	1.00
11_A	33_D	1.469	1.00
18_V	21_Q	1.467	1.00
204_T	209_G	1.467	1.00
411_P	417_E	1.462	1.00
142_E	165_R	1.458	1.00
176_T	313_H	1.454	1.00
99_D	116_T	1.446	1.00
161_T	347_V	1.443	1.00
147_M	347_V	1.439	1.00
46_Q	117_P	1.431	1.00
395_V	439_K	1.429	1.00
18_V	210_T	1.425	1.00
241_T	257_I	1.422	1.00
96_S	149_F	1.417	1.00
187_L	231_I	1.414	1.00
433_K	449_W	1.413	1.00
287_T	356_M	1.411	1.00
458_T	464_A	1.407	1.00
362_G	372_I	1.405	1.00
27_I	61_L	1.402	1.00
304_K	367_E	1.398	1.00
270_K	274_A	1.397	1.00
321_N	327_C	1.395	1.00
430_R	434_A	1.394	1.00
361_M	376_E	1.391	1.00
184_D	233_V	1.389	1.00
218_S	221_K	1.388	1.00
239_T	262_A	1.385	1.00
93_L	98_A	1.385	1.00
161_T	345_G	1.382	1.00
181_S	184_D	1.381	1.00
166_S	291_S	1.376	1.00
17_R	183_D	1.376	1.00
141_P	165_R	1.365	1.00
78_I	96_S	1.365	1.00
295_F	317_I	1.360	1.00
332_I	363_Y	1.358	1.00
185_K	212_C	1.356	1.00
22_T	25_E	1.349	1.00
328_Q	331_E	1.349	1.00
54_A	93_L	1.345	1.00
225_W	229_E	1.331	1.00
317_I	337_V	1.330	1.00
422_V	452_A	1.330	1.00
53_V	75_C	1.327	1.00
227_C	250_F	1.322	1.00
19_A	32_W	1.317	1.00
310_R	369_F	1.315	1.00
338_K	355_W	1.314	1.00
423_I	449_W	1.310	1.00
214_L	225_W	1.308	1.00
48_S	51_N	1.307	1.00
39_T	69_G	1.306	1.00
318_E	355_W	1.297	1.00
304_K	369_F	1.294	1.00
52_R	147_M	1.284	1.00
380_I	389_P	1.281	1.00
433_K	437_K	1.275	1.00
434_A	438_Q	1.271	1.00
420_V	448_K	1.265	1.00
95_I	348_N	1.265	1.00
68_A	205_L	1.263	1.00
259_S	264_W	1.260	1.00
412_D	418_I	1.258	1.00
91_E	95_I	1.257	1.00
437_K	445_I	1.253	1.00
52_R	347_V	1.246	1.00
165_R	340_P	1.245	1.00
404_S	424_L	1.238	1.00
410_I	420_V	1.237	1.00
95_I	156_K	1.237	1.00
311_P	317_I	1.236	1.00
185_K	231_I	1.228	1.00
86_P	110_K	1.223	1.00
76_T	144_P	1.223	1.00
435_W	438_Q	1.222	1.00
35_L	38_Q	1.217	1.00
390_E	394_R	1.216	1.00
161_T	344_S	1.215	1.00
23_E	215_K	1.213	1.00
334_K	376_E	1.212	1.00
378_G	390_E	1.194	1.00
86_P	90_K	1.192	1.00
50_P	143_H	1.191	1.00
409_G	417_E	1.182	1.00
147_M	159_A	1.182	1.00
418_I	447_K	1.175	1.00
234_L	255_V	1.170	1.00
196_H	235_Y	1.170	1.00
272_L	276_W	1.167	1.00
437_K	442_S	1.166	1.00
55_I	66_L	1.163	1.00
297_S	369_F	1.163	1.00
385_L	443_Y	1.153	1.00
139_I	143_H	1.153	1.00
19_A	29_Y	1.153	1.00
429_A	451_F	1.148	1.00
335_I	372_I	1.144	1.00
34_R	38_Q	1.143	1.00
25_E	61_L	1.142	1.00
32_W	68_A	1.140	1.00
422_V	469_K	1.130	1.00
246_R	271_K	1.128	1.00
418_I	448_K	1.127	1.00
56_L	89_C	1.125	1.00
242_D	268_S	1.123	1.00
327_C	331_E	1.121	1.00
27_I	35_L	1.121	1.00
8_S	37_S	1.119	1.00
69_G	73_A	1.115	1.00
48_S	53_V	1.113	1.00
26_Q	229_E	1.105	1.00
94_S	156_K	1.101	1.00
226_L	254_P	1.100	1.00
162_R	166_S	1.089	1.00
21_Q	212_C	1.087	1.00
40_A	72_A	1.084	1.00
42_W	45_S	1.083	1.00
31_D	34_R	1.082	1.00
142_E	163_S	1.082	1.00
245_A	271_K	1.077	1.00
35_L	62_A	1.076	1.00
185_K	232_S	1.071	1.00
421_A	449_W	1.067	1.00
212_C	229_E	1.065	1.00
265_P	268_S	1.061	1.00
63_F	192_L	1.060	1.00
336_F	355_W	1.060	1.00
32_W	65_Q	1.060	1.00
403_E	424_L	1.059	1.00
322_A	376_E	1.057	1.00
150_T	160_F	1.055	1.00
190_G	196_H	1.054	1.00
436_C	445_I	1.053	1.00
308_A	372_I	1.047	1.00
80_I	89_C	1.046	1.00
379_M	388_F	1.045	1.00
401_E	425_G	1.042	1.00
315_V	341_M	1.041	1.00
429_A	449_W	1.038	1.00
105_A	122_D	1.036	1.00
51_N	75_C	1.034	1.00
86_P	113_D	1.033	1.00
399_C	432_L	1.032	1.00
39_T	102_V	1.031	1.00
395_V	398_A	1.026	1.00
429_A	433_K	1.025	1.00
452_A	471_W	1.025	1.00
410_I	448_K	1.024	1.00
212_C	225_W	1.023	1.00
337_V	358_V	1.020	1.00
452_A	455_L	1.017	1.00
431_T	434_A	1.016	1.00
166_S	342_R	1.011	1.00
383_G	415_W	1.009	1.00
393_E	465_R	1.009	1.00
100_L	117_P	1.006	1.00
271_K	275_A	1.001	1.00
184_D	209_G	1.000	1.00
455_L	463_I	1.000	1.00
186_V	204_T	0.998	1.00
88_E	444_K	0.998	1.00
339_S	342_R	0.997	1.00
119_V	123_N	0.994	1.00
467_R	471_W	0.989	1.00
466_S	470_K	0.984	1.00
160_F	343_F	0.983	1.00
338_K	353_D	0.973	1.00
267_E	271_K	0.971	1.00
441_A	444_K	0.969	1.00
36_V	69_G	0.967	1.00
27_I	32_W	0.967	1.00
17_R	210_T	0.966	1.00
87_A	439_K	0.966	1.00
169_E	340_P	0.959	1.00
151_S	460_S	0.959	1.00
52_R	97_N	0.955	1.00
406_A	455_L	0.953	1.00
297_S	307_S	0.952	1.00
91_E	94_S	0.952	1.00
119_V	122_D	0.952	1.00
18_V	28_T	0.948	1.00
48_S	100_L	0.947	1.00
243_A	414_Y	0.946	1.00
20_I	64_L	0.942	1.00
380_I	419_A	0.942	1.00
39_T	66_L	0.942	1.00
84_W	92_R	0.938	1.00
317_I	370_L	0.937	1.00
148_G	288_S	0.936	1.00
319_I	327_C	0.936	1.00
242_D	265_P	0.935	1.00
91_E	149_F	0.934	1.00
87_A	91_E	0.932	1.00
295_F	370_L	0.930	1.00
67_F	77_A	0.928	1.00
57_L	60_S	0.928	1.00
81_D	193_M	0.927	1.00
7_Y	11_A	0.923	1.00
264_W	269_K	0.921	1.00
187_L	214_L	0.918	1.00
169_E	314_N	0.914	1.00
434_A	437_K	0.913	1.00
170_S	292_F	0.912	1.00
87_A	90_K	0.909	1.00
41_N	131_A	0.908	1.00
241_T	272_L	0.907	1.00
43_L	70_A	0.907	1.00
321_N	331_E	0.906	1.00
61_L	65_Q	0.904	1.00
62_A	65_Q	0.903	1.00
41_N	44_R	0.902	1.00
317_I	335_I	0.898	1.00
399_C	431_T	0.897	1.00
171_F	206_F	0.894	1.00
32_W	36_V	0.894	1.00
395_V	436_C	0.893	1.00
304_K	365_D	0.893	1.00
361_M	374_G	0.891	1.00
271_K	274_A	0.890	1.00
25_E	35_L	0.887	1.00
54_A	101_V	0.886	1.00
398_A	435_W	0.883	1.00
352_P	357_T	0.882	1.00
227_C	251_P	0.881	1.00
55_I	77_A	0.873	1.00
217_F	240_M	0.872	1.00
382_Y	409_G	0.871	1.00
162_R	291_S	0.868	1.00
57_L	121_L	0.868	1.00
104_L	107_F	0.868	1.00
91_E	349_G	0.868	1.00
258_I	284_F	0.866	1.00
319_I	370_L	0.864	1.00
58_P	106_F	0.861	1.00
411_P	414_Y	0.861	1.00
44_R	49_M	0.859	1.00
382_Y	447_K	0.859	1.00
204_T	211_V	0.859	1.00
21_Q	185_K	0.858	1.00
67_F	198_L	0.858	1.00
431_T	435_W	0.853	1.00
43_L	102_V	0.851	1.00
31_D	35_L	0.849	1.00
40_A	73_A	0.846	1.00
9_S	12_E	0.841	1.00
324_G	336_F	0.840	1.00
307_S	369_F	0.840	1.00
35_L	61_L	0.839	1.00
145_F	164_H	0.833	1.00
162_R	343_F	0.832	1.00
406_A	468_V	0.831	1.00
8_S	12_E	0.829	1.00
33_D	36_V	0.828	1.00
195_S	287_T	0.828	1.00
70_A	77_A	0.828	1.00
20_I	61_L	0.827	1.00
64_L	213_L	0.821	1.00
195_S	292_F	0.819	1.00
108_K	112_T	0.816	1.00
17_R	182_S	0.813	1.00
185_K	230_S	0.809	1.00
54_A	78_I	0.805	1.00
235_Y	293_V	0.804	1.00
232_S	256_K	0.804	1.00
330_G	366_E	0.801	1.00
6_T	172_T	0.796	1.00
18_V	22_T	0.796	1.00
65_Q	69_G	0.796	1.00
67_F	71_A	0.793	1.00
424_L	454_S	0.782	1.00
378_G	393_E	0.782	1.00
290_L	356_M	0.781	1.00
322_A	334_K	0.781	1.00
432_L	449_W	0.778	1.00
335_I	370_L	0.778	1.00
38_Q	42_W	0.777	1.00
290_L	342_R	0.776	1.00
220_A	224_E	0.773	1.00
7_Y	68_A	0.772	1.00
49_M	75_C	0.772	1.00
107_F	110_K	0.766	1.00
316_R	355_W	0.764	1.00
46_Q	100_L	0.763	1.00
189_P	240_M	0.761	1.00
105_A	120_L	0.761	1.00
48_S	73_A	0.760	1.00
241_T	259_S	0.759	1.00
242_D	246_R	0.759	1.00
237_V	240_M	0.758	1.00
362_G	370_L	0.757	1.00
131_A	134_D	0.756	1.00
318_E	338_K	0.754	1.00
411_P	415_W	0.753	1.00
406_A	463_I	0.752	1.00
139_I	164_H	0.748	1.00
183_D	232_S	0.748	1.00
338_K	354_E	0.747	1.00
6_T	10_T	0.744	1.00
427_A	432_L	0.744	1.00
433_K	445_I	0.743	1.00
32_W	64_L	0.742	1.00
7_Y	33_D	0.742	1.00
70_A	73_A	0.741	1.00
175_E	203_S	0.739	1.00
144_P	163_S	0.738	1.00
242_D	271_K	0.737	1.00
25_E	62_A	0.736	1.00
317_I	362_G	0.735	1.00
87_A	156_K	0.735	1.00
146_Y	162_R	0.733	1.00
332_I	376_E	0.732	1.00
320_R	326_R	0.732	1.00
290_L	337_V	0.731	1.00
78_I	98_A	0.731	1.00
131_A	135_P	0.730	1.00
396_L	405_A	0.730	1.00
224_E	227_C	0.728	1.00
181_S	256_K	0.726	1.00
196_H	260_S	0.726	1.00
442_S	445_I	0.726	1.00
199_Y	235_Y	0.725	1.00
26_Q	210_T	0.723	1.00
430_R	433_K	0.722	1.00
45_S	131_A	0.720	1.00
47_P	75_C	0.719	1.00
57_L	63_F	0.719	1.00
109_N	112_T	0.718	1.00
221_K	225_W	0.717	1.00
170_S	291_S	0.717	1.00
276_W	279_L	0.716	1.00
227_C	253_S	0.711	1.00
422_V	471_W	0.711	1.00
226_L	231_I	0.710	1.00
92_R	159_A	0.709	1.00
105_A	123_N	0.706	1.00
436_C	440_L	0.705	1.00
180_I	233_V	0.705	1.00
194_S	385_L	0.704	1.00
77_A	198_L	0.704	1.00
145_F	167_W	0.703	1.00
395_V	435_W	0.702	1.00
357_T	376_E	0.702	1.00
282_Y	298_P	0.702	1.00
60_S	104_L	0.700	1.00
5_H	8_S	0.700	1.00
410_I	418_I	0.698	1.00
5_H	9_S	0.698	1.00
67_F	202_V	0.696	1.00
16_G	28_T	0.694	1.00
267_E	270_K	0.693	1.00
390_E	393_E	0.692	1.00
56_L	101_V	0.691	1.00
250_F	253_S	0.690	1.00
290_L	294_T	0.689	1.00
54_A	96_S	0.689	1.00
329_P	366_E	0.689	1.00
40_A	69_G	0.681	1.00
342_R	356_M	0.681	1.00
411_P	416_G	0.680	1.00
56_L	107_F	0.679	1.00
66_L	70_A	0.678	1.00
235_Y	284_F	0.678	1.00
103_T	120_L	0.677	1.00
33_D	134_D	0.677	1.00
39_T	43_L	0.677	1.00
39_T	42_W	0.677	1.00
41_N	133_A	0.676	1.00
284_F	293_V	0.674	1.00
53_V	100_L	0.673	1.00
120_L	123_N	0.672	1.00
187_L	225_W	0.671	1.00
188_I	200_G	0.670	1.00
14_S	30_H	0.668	1.00
177_D	313_H	0.667	1.00
257_I	272_L	0.667	1.00
186_V	233_V	0.666	1.00
264_W	281_L	0.664	1.00
406_A	465_R	0.664	1.00
11_A	15_P	0.661	1.00
242_D	267_E	0.661	1.00
10_T	208_G	0.660	1.00
166_S	344_S	0.659	1.00
103_T	118_V	0.659	1.00
362_G	373_S	0.658	1.00
456_P	468_V	0.657	1.00
382_Y	419_A	0.655	1.00
224_E	250_F	0.652	1.00
85_S	88_E	0.651	1.00
248_E	275_A	0.649	1.00
287_T	290_L	0.649	1.00
132_A	135_P	0.648	1.00
170_S	199_Y	0.647	1.00
412_D	415_W	0.647	1.00
41_N	132_A	0.643	1.00
214_L	222_A	0.643	1.00
142_E	344_S	0.642	1.00
187_L	226_L	0.641	1.00
44_R	137_P	0.640	1.00
12_E	33_D	0.640	1.00
22_T	215_K	0.640	1.00
57_L	102_V	0.639	1.00
417_E	469_K	0.637	1.00
44_R	134_D	0.636	1.00
273_A	280_K	0.635	1.00
103_T	107_F	0.633	1.00
200_G	235_Y	0.629	1.00
36_V	40_A	0.628	1.00
68_A	202_V	0.628	1.00
423_I	432_L	0.627	1.00
285_Y	294_T	0.627	1.00
312_F	315_V	0.626	1.00
27_I	31_D	0.626	1.00
36_V	39_T	0.626	1.00
283_D	306_H	0.623	1.00
408_V	469_K	0.623	1.00
57_L	66_L	0.622	1.00
14_S	208_G	0.620	1.00
172_T	206_F	0.619	1.00
190_G	235_Y	0.616	1.00
268_S	271_K	0.615	1.00
189_P	237_V	0.614	1.00
226_L	234_L	0.613	1.00
427_A	431_T	0.613	1.00
382_Y	415_W	0.612	1.00
103_T	108_K	0.611	1.00
326_R	336_F	0.611	1.00
389_P	407_V	0.609	1.00
172_T	176_T	0.607	1.00
389_P	465_R	0.606	1.00
217_F	222_A	0.605	1.00
180_I	184_D	0.605	1.00
170_S	293_V	0.605	1.00
20_I	211_V	0.605	1.00
41_N	134_D	0.604	1.00
225_W	228_R	0.604	1.00
249_G	252_D	0.603	1.00
330_G	363_Y	0.602	1.00
287_T	358_V	0.602	1.00
97_N	347_V	0.599	1.00
14_S	182_S	0.599	1.00
45_S	130_E	0.598	1.00
234_L	257_I	0.597	1.00
227_C	254_P	0.596	1.00
171_F	202_V	0.595	1.00
110_K	113_D	0.595	1.00
319_I	364_V	0.594	1.00
210_T	229_E	0.593	1.00
6_T	168_M	0.592	1.00
78_I	149_F	0.592	1.00
62_A	104_L	0.592	1.00
146_Y	167_W	0.592	1.00
95_I	347_V	0.591	1.00
422_V	450_V	0.590	1.00
52_R	348_N	0.590	1.00
345_G	350_S	0.590	1.00
147_M	161_T	0.589	1.00
131_A	136_L	0.589	1.00
450_V	471_W	0.588	1.00
76_T	147_M	0.588	1.00
38_Q	41_N	0.585	1.00
108_K	120_L	0.585	1.00
180_I	209_G	0.583	1.00
34_R	132_A	0.582	1.00
308_A	362_G	0.582	1.00
188_I	211_V	0.582	1.00
6_T	206_F	0.582	1.00
174_T	199_Y	0.581	1.00
156_K	349_G	0.581	1.00
402_V	405_A	0.579	1.00
146_Y	198_L	0.578	1.00
272_L	281_L	0.576	1.00
143_H	164_H	0.574	1.00
270_K	273_A	0.573	1.00
37_S	44_R	0.573	1.00
396_L	436_C	0.572	1.00
263_D	372_I	0.572	1.00
380_I	409_G	0.571	1.00
49_M	99_D	0.571	1.00
222_A	226_L	0.570	1.00
395_V	440_L	0.568	1.00
29_Y	209_G	0.567	1.00
95_I	159_A	0.566	1.00
57_L	103_T	0.565	1.00
57_L	104_L	0.564	1.00
41_N	45_S	0.564	1.00
377_N	417_E	0.563	1.00
196_H	258_I	0.563	1.00
264_W	283_D	0.562	1.00
76_T	347_V	0.561	1.00
56_L	111_L	0.561	1.00
101_V	111_L	0.559	1.00
191_A	194_S	0.559	1.00
21_Q	24_S	0.559	1.00
18_V	185_K	0.558	1.00
319_I	335_I	0.558	1.00
428_N	451_F	0.558	1.00
170_S	174_T	0.557	1.00
402_V	423_I	0.557	1.00
259_S	281_L	0.556	1.00
172_T	175_E	0.556	1.00
115_Q	119_V	0.555	1.00
399_C	402_V	0.555	1.00
319_I	333_G	0.555	1.00
392_I	419_A	0.553	1.00
189_P	236_T	0.552	1.00
52_R	98_A	0.552	1.00
389_P	409_G	0.552	1.00
117_P	120_L	0.552	1.00
394_R	398_A	0.551	1.00
173_C	177_D	0.550	1.00
79_P	148_G	0.550	1.00
67_F	201_A	0.550	1.00
99_D	117_P	0.550	1.00
37_S	134_D	0.548	1.00
55_I	70_A	0.548	1.00
185_K	188_I	0.548	1.00
188_I	213_L	0.548	1.00
404_S	455_L	0.547	1.00
55_I	63_F	0.547	1.00
326_R	364_V	0.547	1.00
320_R	355_W	0.546	1.00
412_D	416_G	0.546	1.00
193_M	385_L	0.545	1.00
394_R	397_L	0.545	1.00
35_L	39_T	0.544	1.00
448_K	451_F	0.544	1.00
44_R	135_P	0.543	1.00
42_W	128_I	0.543	1.00
38_Q	132_A	0.542	1.00
43_L	100_L	0.542	1.00
247_I	275_A	0.539	1.00
393_E	421_A	0.539	1.00
235_Y	260_S	0.538	1.00
123_N	127_D	0.538	1.00
155_G	388_F	0.537	1.00
96_S	159_A	0.537	1.00
295_F	308_A	0.536	1.00
401_E	435_W	0.536	1.00
445_I	449_W	0.536	1.00
188_I	197_F	0.534	1.00
429_A	448_K	0.534	1.00
199_Y	293_V	0.532	1.00
84_W	89_C	0.531	1.00
260_S	284_F	0.531	1.00
100_L	119_V	0.531	1.00
29_Y	205_L	0.531	1.00
94_S	114_S	0.530	1.00
187_L	222_A	0.530	1.00
88_E	391_E	0.530	1.00
410_I	422_V	0.529	1.00
76_T	79_P	0.528	1.00
186_V	209_G	0.526	1.00
433_K	436_C	0.525	1.00
413_E	416_G	0.525	1.00
382_Y	417_E	0.524	1.00
37_S	133_A	0.524	1.00
96_S	147_M	0.524	1.00
160_F	288_S	0.524	1.00
331_E	363_Y	0.522	1.00
297_S	300_D	0.522	1.00
316_R	353_D	0.520	1.00
238_P	262_A	0.518	1.00
270_K	305_P	0.517	1.00
33_D	135_P	0.517	1.00
232_S	254_P	0.516	1.00
103_T	111_L	0.516	1.00
243_A	246_R	0.516	1.00
374_G	389_P	0.513	1.00
257_I	279_L	0.513	1.00
133_A	136_L	0.512	1.00
259_S	283_D	0.511	1.00
114_S	119_V	0.510	1.00
359_D	377_N	0.510	1.00
466_S	469_K	0.510	1.00
454_S	457_E	0.509	1.00
337_V	342_R	0.508	1.00
378_G	389_P	0.508	1.00
43_L	75_C	0.507	1.00
320_R	324_G	0.507	1.00
247_I	250_F	0.507	1.00
379_M	386_N	0.506	1.00
58_P	107_F	0.506	1.00
41_N	135_P	0.505	1.00
269_K	283_D	0.505	1.00
56_L	110_K	0.505	1.00
20_I	27_I	0.504	1.00
343_F	356_M	0.504	1.00
78_I	92_R	0.504	1.00
5_H	138_T	0.502	1.00
75_C	100_L	0.502	1.00
215_K	221_K	0.501	1.00
294_T	315_V	0.500	1.00
245_A	268_S	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tsyA	2	0.7891	100	0.121	Contact Map
2vsqA	1	0.9958	100	0.129	Contact Map
4lgcA	1	0.7578	100	0.13	Contact Map
1mdbA	1	0.9958	100	0.132	Contact Map
3wvnA	1	0.762	100	0.133	Contact Map
3ni2A	1	0.9833	100	0.135	Contact Map
3g7sA	2	0.9081	100	0.137	Contact Map
3o83A	1	0.7871	100	0.137	Contact Map
2d1sA	1	0.9916	100	0.138	Contact Map
3etcA	2	0.9499	100	0.141	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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