YHFP - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YHFP - Putative quinone oxidoreductase YhfP

UniProt:	O07615	Sequences: MSTLFQALQAEKNADDVSVHVKTISTEDLPKDGVLIKVAYSGINYKDGLAGKAGGNIVREYPLILGIDAAGTVVSSNDPRFAEGDEVIATSYELGVSRDGGLSEYASVPGDWLVPLPQNLSLKEAMVYGTAGFTAALSVHRLEQNGLSPEKGSVLVTGATGGVGGIAVSMLNKRGYDVVASTGNREAADYLKQLGASEVISREDVYDGTLKALSKQQWQGAVDPVGGKQLASLLSKIQYGGSVAVSGLTGGGEVPATVYPFILRGVSLLGIDSVYCPMDVRAAVWERMSSDLKPDQLLTIVDREVSLEETPGALKDILQNRIQGRVIVKL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	330 (302)
Sequences:	52961 (36353)
Seq/√Len:	2091.9

ECOLI - ACUI CURA YGGP YBDR QOR1 YAHK AHR RSPB YPHC ADHP FRMA YDJL TDH IDND GATD YJJN YCJQ YDJJ
BACSU - YHFP YOGA YFMJ DHSO ADHB BDHA YJMD ADHA YYCR TDH
HALSA - Q9HP38 Q9HR85 Q9HMB6 Q9HQS8 GLCDH
SULSO - Q97YT7 ADH Q7LXK1 Q97ZV3 Q97VW0 Q97WA1 Q97YM2 Q97V32 Q97VV5 Q97XR4 GLCD2 Q97TZ4 GLCD1 GLCD3 Q97W06 Q97UW5 Q97VB8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
309_E	312_G	3.019	1.00
39_A	122_L	2.955	1.00
37_K	74_V	2.901	1.00
39_A	72_T	2.851	1.00
11_E	22_K	2.830	1.00
35_L	74_V	2.707	1.00
153_S	177_D	2.601	1.00
121_S	124_E	2.552	1.00
34_V	113_L	2.540	1.00
172_N	197_S	2.437	1.00
82_A	85_D	2.414	1.00
305_V	316_D	2.406	1.00
85_D	115_P	2.404	1.00
86_E	116_L	2.354	1.00
37_K	72_T	2.301	1.00
26_T	105_Y	2.253	1.00
11_E	20_H	2.239	1.00
123_K	304_E	2.236	1.00
303_R	316_D	2.190	1.00
9_Q	22_K	2.167	1.00
290_S	294_P	2.162	1.00
37_K	105_Y	2.156	1.00
154_V	171_L	2.136	1.00
188_A	192_K	2.118	1.00
80_R	110_G	2.111	1.00
177_D	198_E	2.100	1.00
30_P	33_G	2.083	1.00
69_A	101_G	2.081	1.00
189_D	193_Q	2.034	1.00
306_S	309_E	2.027	1.00
119_N	293_K	2.012	1.00
31_K	78_D	2.011	1.00
168_V	196_A	1.996	1.00
315_K	319_Q	1.961	1.00
148_S	152_G	1.935	1.00
69_A	89_A	1.924	1.00
28_D	75_S	1.898	1.00
70_A	122_L	1.889	1.00
208_G	211_K	1.858	1.00
35_L	107_S	1.847	1.00
74_V	105_Y	1.826	1.00
86_E	122_L	1.812	1.00
52_K	318_L	1.809	1.00
185_R	189_D	1.801	1.00
132_G	166_I	1.782	1.00
189_D	192_K	1.778	1.00
173_K	296_Q	1.775	1.00
312_G	315_K	1.771	1.00
219_Q	238_Q	1.716	1.00
155_L	181_S	1.714	1.00
316_D	321_R	1.705	1.00
155_L	218_W	1.701	1.00
152_G	242_S	1.688	1.00
242_S	267_S	1.685	1.00
305_V	313_A	1.674	1.00
179_V	218_W	1.663	1.00
116_L	122_L	1.649	1.00
312_G	316_D	1.644	1.00
190_Y	193_Q	1.640	1.00
182_T	188_A	1.639	1.00
188_A	199_V	1.633	1.00
76_S	83_E	1.600	1.00
157_T	233_L	1.577	1.00
177_D	197_S	1.572	1.00
8_L	310_T	1.571	1.00
242_S	269_L	1.565	1.00
6_Q	23_T	1.555	1.00
81_F	115_P	1.552	1.00
75_S	83_E	1.535	1.00
29_L	107_S	1.521	1.00
81_F	85_D	1.506	1.00
185_R	201_S	1.499	1.00
237_I	266_V	1.499	1.00
35_L	105_Y	1.498	1.00
145_N	220_G	1.498	1.00
33_G	109_P	1.486	1.00
237_I	243_V	1.479	1.00
72_T	86_E	1.452	1.00
38_V	69_A	1.438	1.00
32_D	109_P	1.432	1.00
116_L	125_A	1.428	1.00
29_L	35_L	1.423	1.00
6_Q	308_E	1.418	1.00
221_A	237_I	1.404	1.00
311_P	315_K	1.403	1.00
102_L	314_L	1.403	1.00
237_I	241_G	1.402	1.00
6_Q	104_E	1.396	1.00
168_V	180_A	1.377	1.00
40_Y	123_K	1.377	1.00
221_A	233_L	1.375	1.00
33_G	107_S	1.362	1.00
302_D	316_D	1.345	1.00
201_S	204_D	1.344	1.00
7_A	24_I	1.340	1.00
185_R	204_D	1.334	1.00
73_V	81_F	1.332	1.00
35_L	75_S	1.326	1.00
86_E	118_Q	1.323	1.00
160_T	180_A	1.318	1.00
34_V	81_F	1.295	1.00
290_S	293_K	1.287	1.00
173_K	291_D	1.282	1.00
72_T	122_L	1.282	1.00
153_S	179_V	1.265	1.00
157_T	181_S	1.245	1.00
143_E	287_R	1.238	1.00
167_A	222_V	1.238	1.00
8_L	21_V	1.238	1.00
51_G	314_L	1.232	1.00
209_T	212_A	1.230	1.00
183_G	188_A	1.220	1.00
147_L	176_Y	1.216	1.00
207_D	211_K	1.214	1.00
183_G	202_R	1.208	1.00
32_D	110_G	1.172	1.00
39_A	86_E	1.172	1.00
185_R	188_A	1.171	1.00
81_F	113_L	1.170	1.00
26_T	35_L	1.163	1.00
192_K	199_V	1.149	1.00
198_E	212_A	1.135	1.00
205_V	208_G	1.131	1.00
287_R	290_S	1.124	1.00
124_E	298_L	1.124	1.00
12_K	18_S	1.121	1.00
36_I	71_G	1.118	1.00
143_E	284_V	1.111	1.00
29_L	33_G	1.108	1.00
38_V	106_A	1.104	1.00
188_A	201_S	1.104	1.00
235_S	260_P	1.103	1.00
208_G	212_A	1.101	1.00
153_S	219_Q	1.097	1.00
160_T	182_T	1.091	1.00
169_S	298_L	1.088	1.00
152_G	219_Q	1.086	1.00
282_A	286_E	1.083	1.00
108_V	113_L	1.083	1.00
192_K	198_E	1.076	1.00
8_L	307_L	1.069	1.00
74_V	83_E	1.065	1.00
43_I	313_A	1.050	1.00
291_D	296_Q	1.033	1.00
32_D	78_D	1.030	1.00
286_E	290_S	1.028	1.00
137_L	284_V	1.027	1.00
190_Y	323_Q	1.027	1.00
179_V	198_E	1.026	1.00
41_S	102_L	1.017	1.00
145_N	244_A	1.016	1.00
180_A	196_A	1.015	1.00
135_A	167_A	1.012	1.00
36_I	87_V	1.010	1.00
51_G	318_L	1.008	1.00
144_Q	267_S	1.006	1.00
21_V	308_E	0.995	1.00
225_V	229_Q	0.993	1.00
210_L	213_L	0.979	1.00
9_Q	24_I	0.975	1.00
39_A	70_A	0.975	1.00
40_Y	122_L	0.971	1.00
206_Y	210_L	0.963	1.00
209_T	213_L	0.962	1.00
135_A	170_M	0.960	1.00
102_L	310_T	0.945	1.00
26_T	75_S	0.944	1.00
231_A	235_S	0.942	1.00
120_L	125_A	0.937	1.00
315_K	318_L	0.935	1.00
171_L	176_Y	0.934	1.00
310_T	328_V	0.934	1.00
132_G	288_M	0.929	1.00
7_A	64_I	0.927	1.00
138_S	246_S	0.925	1.00
179_V	200_I	0.924	1.00
32_D	77_N	0.921	1.00
44_N	68_D	0.921	1.00
136_A	287_R	0.918	1.00
316_D	326_V	0.915	1.00
168_V	178_V	0.911	1.00
232_S	235_S	0.910	1.00
76_S	79_P	0.909	1.00
206_Y	209_T	0.907	1.00
8_L	19_V	0.905	1.00
223_D	226_G	0.898	1.00
9_Q	64_I	0.895	1.00
37_K	104_E	0.890	1.00
170_M	288_M	0.888	1.00
48_G	317_I	0.887	1.00
156_V	167_A	0.886	1.00
260_P	264_R	0.881	1.00
261_F	268_L	0.876	1.00
12_K	17_V	0.876	1.00
138_S	222_V	0.874	1.00
156_V	171_L	0.873	1.00
69_A	106_A	0.872	1.00
155_L	236_K	0.871	1.00
41_S	101_G	0.870	1.00
40_Y	327_I	0.867	1.00
6_Q	21_V	0.866	1.00
180_A	191_L	0.862	1.00
165_G	190_Y	0.861	1.00
207_D	210_L	0.861	1.00
26_T	74_V	0.856	1.00
128_Y	292_L	0.853	1.00
28_D	35_L	0.853	1.00
213_L	216_Q	0.853	1.00
184_N	187_A	0.846	1.00
157_T	221_A	0.846	1.00
88_I	289_S	0.842	1.00
152_G	220_G	0.842	1.00
186_E	189_D	0.842	1.00
82_A	115_P	0.841	1.00
181_S	202_R	0.840	1.00
193_Q	298_L	0.839	1.00
183_G	203_E	0.833	1.00
29_L	77_N	0.832	1.00
30_P	107_S	0.832	1.00
210_L	214_S	0.829	1.00
44_N	67_I	0.828	1.00
63_L	99_D	0.827	1.00
102_L	328_V	0.824	1.00
148_S	151_K	0.824	1.00
42_G	68_D	0.822	1.00
187_A	323_Q	0.822	1.00
287_R	291_D	0.821	1.00
240_G	265_G	0.820	1.00
283_A	287_R	0.814	1.00
139_V	171_L	0.813	1.00
133_F	284_V	0.813	1.00
160_T	191_L	0.811	1.00
147_L	152_G	0.811	1.00
24_I	99_D	0.811	1.00
76_S	82_A	0.809	1.00
191_L	196_A	0.800	1.00
184_N	201_S	0.799	1.00
153_S	218_W	0.799	1.00
257_T	260_P	0.798	1.00
11_E	18_S	0.797	1.00
118_Q	293_K	0.796	1.00
305_V	309_E	0.796	1.00
79_P	110_G	0.795	1.00
170_M	291_D	0.794	1.00
144_Q	269_L	0.790	1.00
209_T	214_S	0.788	1.00
43_I	317_I	0.783	1.00
182_T	199_V	0.777	1.00
317_I	326_V	0.776	1.00
34_V	110_G	0.775	1.00
283_A	286_E	0.772	1.00
8_L	311_P	0.770	1.00
138_S	167_A	0.767	1.00
193_Q	300_I	0.766	1.00
21_V	307_L	0.760	1.00
221_A	243_V	0.758	1.00
291_D	294_P	0.753	1.00
157_T	229_Q	0.752	1.00
171_L	178_V	0.748	1.00
183_G	191_L	0.748	1.00
29_L	75_S	0.747	1.00
291_D	295_D	0.746	1.00
174_R	287_R	0.746	1.00
135_A	166_I	0.743	1.00
87_V	113_L	0.740	1.00
233_L	243_V	0.740	1.00
303_R	312_G	0.737	1.00
178_V	197_S	0.736	1.00
228_K	232_S	0.734	1.00
261_F	270_G	0.732	1.00
114_V	286_E	0.732	1.00
117_P	293_K	0.732	1.00
154_V	176_Y	0.728	1.00
147_L	220_G	0.726	1.00
316_D	319_Q	0.726	1.00
322_I	326_V	0.720	1.00
146_G	242_S	0.719	1.00
153_S	216_Q	0.719	1.00
224_P	246_S	0.718	1.00
46_K	67_I	0.717	1.00
89_A	108_V	0.711	1.00
135_A	163_V	0.711	1.00
120_L	292_L	0.710	1.00
261_F	266_V	0.708	1.00
101_G	106_A	0.706	1.00
303_R	326_V	0.704	1.00
44_N	47_D	0.702	1.00
80_R	282_A	0.699	1.00
137_L	265_G	0.693	1.00
24_I	64_I	0.693	1.00
136_A	288_M	0.693	1.00
40_Y	304_E	0.691	1.00
301_V	304_E	0.690	1.00
305_V	328_V	0.690	1.00
68_D	130_T	0.689	1.00
70_A	126_M	0.686	1.00
43_I	102_L	0.684	1.00
10_A	18_S	0.684	1.00
239_Y	264_R	0.684	1.00
88_I	116_L	0.683	1.00
200_I	205_V	0.682	1.00
206_Y	232_S	0.680	1.00
245_V	268_L	0.675	1.00
17_V	315_K	0.674	1.00
29_L	32_D	0.671	1.00
146_G	269_L	0.669	1.00
146_G	267_S	0.666	1.00
170_M	174_R	0.665	1.00
55_G	59_R	0.663	1.00
220_G	244_A	0.660	1.00
136_A	291_D	0.658	1.00
135_A	139_V	0.657	1.00
156_V	180_A	0.655	1.00
32_D	111_D	0.655	1.00
121_S	125_A	0.653	1.00
230_L	243_V	0.653	1.00
44_N	130_T	0.653	1.00
76_S	85_D	0.651	1.00
12_K	20_H	0.651	1.00
176_Y	220_G	0.649	1.00
80_R	115_P	0.648	1.00
190_Y	300_I	0.647	1.00
114_V	285_W	0.646	1.00
216_Q	238_Q	0.646	1.00
27_E	107_S	0.645	1.00
165_G	300_I	0.642	1.00
218_W	221_A	0.642	1.00
231_A	260_P	0.642	1.00
80_R	83_E	0.640	1.00
190_Y	194_L	0.639	1.00
88_I	129_G	0.639	1.00
44_N	131_A	0.638	1.00
289_S	293_K	0.638	1.00
213_L	217_Q	0.636	1.00
31_K	77_N	0.635	1.00
95_G	99_D	0.635	1.00
218_W	236_K	0.634	1.00
143_E	174_R	0.632	1.00
305_V	326_V	0.632	1.00
114_V	289_S	0.631	1.00
127_V	327_I	0.628	1.00
40_Y	70_A	0.627	1.00
86_E	119_N	0.623	1.00
70_A	116_L	0.623	1.00
145_N	242_S	0.619	1.00
67_I	130_T	0.619	1.00
168_V	194_L	0.619	1.00
34_V	73_V	0.617	1.00
205_V	209_T	0.613	1.00
168_V	191_L	0.612	1.00
36_I	89_A	0.611	1.00
38_V	41_S	0.610	1.00
314_L	318_L	0.610	1.00
85_D	118_Q	0.609	1.00
131_A	166_I	0.604	1.00
220_G	242_S	0.602	1.00
134_T	163_V	0.602	1.00
169_S	194_L	0.602	1.00
70_A	86_E	0.602	1.00
136_A	284_V	0.602	1.00
223_D	243_V	0.599	1.00
130_T	134_T	0.598	1.00
131_A	162_G	0.596	1.00
206_Y	235_S	0.595	1.00
229_Q	233_L	0.594	1.00
55_G	58_V	0.592	1.00
45_Y	49_L	0.591	1.00
46_K	50_A	0.590	1.00
30_P	77_N	0.589	1.00
48_G	318_L	0.588	1.00
160_T	168_V	0.587	1.00
259_Y	262_I	0.586	1.00
231_A	253_E	0.585	1.00
188_A	191_L	0.585	1.00
204_D	208_G	0.583	1.00
228_K	231_A	0.581	1.00
182_T	191_L	0.581	1.00
138_S	271_I	0.580	1.00
182_T	201_S	0.580	1.00
221_A	236_K	0.579	1.00
172_N	178_V	0.577	1.00
292_L	299_T	0.577	1.00
49_L	54_G	0.576	1.00
206_Y	213_L	0.575	1.00
265_G	275_Y	0.575	1.00
27_E	105_Y	0.572	1.00
89_A	113_L	0.572	1.00
181_S	200_I	0.563	1.00
154_V	220_G	0.563	1.00
167_A	246_S	0.563	1.00
155_L	221_A	0.563	1.00
16_D	315_K	0.563	1.00
110_G	113_L	0.561	1.00
76_S	81_F	0.560	1.00
12_K	16_D	0.560	1.00
188_A	202_R	0.559	1.00
79_P	82_A	0.559	1.00
136_A	174_R	0.556	1.00
114_V	282_A	0.552	1.00
143_E	146_G	0.549	1.00
27_E	35_L	0.549	1.00
66_G	102_L	0.548	1.00
179_V	212_A	0.546	1.00
90_T	114_V	0.545	1.00
60_E	63_L	0.545	1.00
70_A	125_A	0.543	1.00
48_G	52_K	0.542	1.00
260_P	266_V	0.541	1.00
26_T	107_S	0.541	1.00
166_I	170_M	0.540	1.00
26_T	29_L	0.540	1.00
316_D	322_I	0.539	1.00
134_T	246_S	0.538	1.00
27_E	33_G	0.537	1.00
262_I	270_G	0.534	1.00
81_F	110_G	0.533	1.00
19_V	314_L	0.533	1.00
121_S	304_E	0.533	1.00
62_P	66_G	0.532	1.00
46_K	49_L	0.532	1.00
45_Y	161_G	0.531	1.00
182_T	202_R	0.531	1.00
56_N	59_R	0.530	1.00
182_T	187_A	0.529	1.00
244_A	271_I	0.529	1.00
44_N	325_R	0.528	1.00
21_V	310_T	0.526	1.00
25_S	28_D	0.525	1.00
160_T	187_A	0.524	1.00
10_A	51_G	0.524	1.00
260_P	263_L	0.523	1.00
127_V	299_T	0.523	1.00
139_V	170_M	0.521	1.00
18_S	311_P	0.521	1.00
271_I	274_V	0.520	1.00
204_D	209_T	0.515	1.00
139_V	167_A	0.515	1.00
271_I	275_Y	0.514	1.00
143_E	283_A	0.512	1.00
253_E	257_T	0.511	1.00
172_N	196_A	0.511	1.00
78_D	110_G	0.510	1.00
231_A	255_P	0.510	1.00
41_S	328_V	0.509	1.00
305_V	312_G	0.508	1.00
138_S	244_A	0.508	1.00
196_A	199_V	0.504	1.00
191_L	199_V	0.504	1.00
223_D	247_G	0.503	1.00
34_V	76_S	0.502	1.00
115_P	118_Q	0.501	1.00
42_G	126_M	0.501	1.00
17_V	51_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1tt7A	5	0.9939	100	0.153	Contact Map
3nx4A	2	0.9758	100	0.158	Contact Map
4j6fA	2	0.9667	100	0.169	Contact Map
4gi2A	2	0.9788	100	0.17	Contact Map
3uogA	4	0.9636	100	0.172	Contact Map
4jxkA	2	0.9818	100	0.173	Contact Map
1zsyA	2	0.9758	100	0.18	Contact Map
4a27A	2	0.9152	100	0.18	Contact Map
1xa0A	2	0.9758	100	0.182	Contact Map
4dupA	2	0.9697	100	0.186	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0093 seconds.