LCFB - BACSU - GREMLIN Contacts

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LCFB - Long-chain-fatty-acid--CoA ligase

UniProt:	O07610	Sequences: MNLVSKLEETASEKPDSIACRFKDHMMTYQELNEYIQRFADGLQEAGMEKGDHLALLLGNSPDFIIAFFGALKAGIVVVPINPLYTPTEIGYMLTNGDVKAIVGVSQLLPLYESMHESLPKVELVILCQTGEAEPEAADPEVRMKMTTFAKILRPTSAAKQNQEPVPDDTAVILYTSGTTGKPKGAMLTHQNLYSNANDVAGYLGMDERDNVVCALPMFHVFCLTVCMNAPLMSGATVLIEPQFSPASVFKLVKQQQATIFAGVPTMYNYLFQHENGKKDDFSSIRLCISGGASMPVALLTAFEEKFGVTILEGYGLSEASPVTCFNPFDRGRKPGSIGTSILHVENKVVDPLGRELPAHQVGELIVKGPNVMKGYYKMPMETEHALKDGWLYTGDLARRDEDGYFYIVDRKKDMIIVGGYNVYPREVEEVLYSHPDVKEAVVIGVPDPQSGEAVKGYVVPKRSGVTEEDIMQHCEKHLAKYKRPAAITFLDDIPKNATGKMLRRALRDILPQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	513 (481)
Sequences:	71143 (50957)
Seq/√Len:	2323.4

ECOLI - ENTF ACSA LCFA AAS FADK PRPE CAIC ENTE MENE PAAK
BACSU - LCFB SRFAC PPSE LCFA ACSA YDAB DHBE YNGI YTCI PPSB MENE PPSC DLTA YHFT DHBF PKSJ PPSD PPSA SRFAB SRFAA PKSN
HALSA - Q9HRY8 Q9HQU8 Q9HSM3 Q9HQ43 Q9HNK0 Q9HQN8
SULSO - Q97UX8 Q97UW7 Q97YK9 Q97U22 Q97VT6 Q97WQ9 Q97VU7 Q97WQ0 Q97XW4 Q97UF6 Q97WK0 Q97V27 Q97WS5 Q980E4 Q97X52 Q97XW5 Q97VJ6 Q97WU3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
170_T	187_M	3.856	1.00
435_H	474_H	3.123	1.00
365_L	398_A	3.055	1.00
37_Q	73_K	2.916	1.00
346_E	368_K	2.901	1.00
379_M	382_E	2.881	1.00
96_N	175_Y	2.799	1.00
55_A	99_V	2.777	1.00
189_T	374_K	2.745	1.00
52_D	100_K	2.727	1.00
399_R	407_Y	2.690	1.00
33_N	73_K	2.683	1.00
48_M	76_I	2.651	1.00
21_R	237_T	2.604	1.00
364_E	393_Y	2.476	1.00
211_N	237_T	2.422	1.00
18_I	26_M	2.372	1.00
417_I	422_N	2.367	1.00
98_D	378_K	2.346	1.00
440_E	496_K	2.326	1.00
14_K	17_S	2.282	1.00
433_Y	441_A	2.280	1.00
53_H	79_V	2.275	1.00
350_V	366_I	2.234	1.00
8_E	33_N	2.231	1.00
42_G	46_A	2.223	1.00
348_K	356_E	2.200	1.00
432_L	457_G	2.187	1.00
362_V	397_L	2.175	1.00
351_D	355_R	2.163	1.00
35_Y	66_I	2.161	1.00
366_I	393_Y	2.156	1.00
10_T	14_K	2.132	1.00
92_Y	182_K	2.128	1.00
67_A	103_V	2.110	1.00
96_N	379_M	2.108	1.00
33_N	37_Q	2.072	1.00
503_L	506_A	2.063	1.00
401_D	407_Y	2.060	1.00
456_K	489_T	2.034	1.00
251_K	255_Q	2.028	1.00
22_F	62_P	2.027	1.00
166_V	169_D	1.997	1.00
414_D	504_R	1.985	1.00
210_D	286_R	1.984	1.00
71_A	76_I	1.981	1.00
382_E	385_H	1.970	1.00
434_S	478_H	1.942	1.00
401_D	405_Y	1.942	1.00
399_R	409_V	1.917	1.00
380_P	384_E	1.892	1.00
210_D	259_T	1.878	1.00
348_K	366_I	1.866	1.00
39_F	66_I	1.861	1.00
21_R	26_M	1.854	1.00
297_V	301_T	1.853	1.00
50_K	169_D	1.840	1.00
337_S	407_Y	1.827	1.00
91_G	95_T	1.819	1.00
16_D	30_Q	1.813	1.00
49_E	52_D	1.776	1.00
44_Q	74_A	1.773	1.00
51_G	169_D	1.733	1.00
21_R	256_Q	1.731	1.00
427_E	483_K	1.724	1.00
36_I	73_K	1.713	1.00
400_R	406_F	1.705	1.00
257_Q	284_S	1.700	1.00
9_E	13_E	1.698	1.00
506_A	509_D	1.696	1.00
439_K	462_K	1.696	1.00
30_Q	34_E	1.694	1.00
418_V	423_V	1.663	1.00
362_V	409_V	1.660	1.00
239_L	258_A	1.650	1.00
433_Y	440_E	1.649	1.00
429_E	443_V	1.647	1.00
59_G	105_V	1.629	1.00
444_I	458_Y	1.629	1.00
65_I	228_M	1.626	1.00
189_T	192_N	1.608	1.00
28_T	31_E	1.607	1.00
359_A	400_R	1.600	1.00
170_T	374_K	1.562	1.00
55_A	81_I	1.557	1.00
458_Y	507_L	1.554	1.00
72_L	171_A	1.551	1.00
460_V	494_I	1.540	1.00
443_V	457_G	1.536	1.00
10_T	13_E	1.533	1.00
53_H	77_V	1.523	1.00
263_G	268_Y	1.517	1.00
27_M	66_I	1.508	1.00
381_M	385_H	1.501	1.00
248_S	251_K	1.499	1.00
437_D	470_D	1.495	1.00
324_T	367_V	1.489	1.00
310_T	328_P	1.488	1.00
459_V	490_F	1.487	1.00
201_A	234_S	1.477	1.00
175_Y	185_G	1.477	1.00
15_P	30_Q	1.465	1.00
474_H	478_H	1.461	1.00
431_V	478_H	1.461	1.00
349_V	398_A	1.459	1.00
54_L	71_A	1.458	1.00
231_P	236_A	1.456	1.00
17_S	209_R	1.455	1.00
8_E	73_K	1.454	1.00
18_I	21_R	1.451	1.00
461_P	490_F	1.444	1.00
447_P	453_E	1.440	1.00
202_G	343_L	1.434	1.00
42_G	152_I	1.433	1.00
18_I	237_T	1.432	1.00
334_K	403_D	1.431	1.00
173_I	377_Y	1.424	1.00
37_Q	41_D	1.424	1.00
11_A	33_N	1.419	1.00
97_G	175_Y	1.409	1.00
168_D	191_Q	1.407	1.00
213_V	258_A	1.406	1.00
358_P	361_Q	1.404	1.00
254_K	280_D	1.396	1.00
301_T	305_E	1.396	1.00
187_M	377_Y	1.390	1.00
458_Y	508_R	1.389	1.00
497_N	503_L	1.387	1.00
317_L	392_L	1.386	1.00
94_L	99_V	1.386	1.00
398_A	408_I	1.381	1.00
266_T	293_A	1.379	1.00
27_M	62_P	1.376	1.00
187_M	375_G	1.372	1.00
472_M	488_I	1.370	1.00
245_S	248_S	1.365	1.00
192_N	321_S	1.358	1.00
167_P	191_Q	1.350	1.00
210_D	260_I	1.349	1.00
362_V	399_R	1.347	1.00
325_C	347_N	1.346	1.00
55_A	94_L	1.345	1.00
458_Y	491_L	1.341	1.00
373_M	387_L	1.336	1.00
459_V	488_I	1.332	1.00
211_N	239_L	1.331	1.00
19_A	32_L	1.329	1.00
79_V	97_G	1.328	1.00
207_D	210_D	1.328	1.00
46_A	124_L	1.322	1.00
397_L	412_K	1.321	1.00
22_F	25_H	1.318	1.00
351_D	357_L	1.314	1.00
448_D	454_A	1.312	1.00
54_L	76_I	1.311	1.00
268_Y	288_C	1.310	1.00
368_K	391_W	1.304	1.00
467_T	470_D	1.297	1.00
252_L	256_Q	1.297	1.00
347_N	367_V	1.297	1.00
386_A	392_L	1.293	1.00
39_F	70_G	1.292	1.00
87_P	111_L	1.290	1.00
476_E	484_R	1.289	1.00
340_T	405_Y	1.284	1.00
241_E	252_L	1.284	1.00
334_K	405_Y	1.280	1.00
53_H	173_I	1.274	1.00
290_S	295_M	1.274	1.00
96_N	378_K	1.272	1.00
45_E	156_T	1.268	1.00
473_Q	477_K	1.267	1.00
69_F	232_L	1.262	1.00
456_K	487_A	1.255	1.00
416_I	425_P	1.247	1.00
51_G	374_K	1.247	1.00
446_V	456_K	1.245	1.00
92_Y	96_N	1.241	1.00
87_P	114_S	1.241	1.00
440_E	460_V	1.240	1.00
472_M	476_E	1.237	1.00
48_M	52_D	1.231	1.00
77_V	170_T	1.230	1.00
341_S	347_N	1.222	1.00
53_H	377_Y	1.219	1.00
35_Y	38_R	1.215	1.00
211_N	258_A	1.211	1.00
96_N	182_K	1.211	1.00
191_Q	370_P	1.211	1.00
187_M	374_K	1.210	1.00
348_K	391_W	1.209	1.00
261_F	285_I	1.206	1.00
48_M	54_L	1.203	1.00
364_E	412_K	1.198	1.00
474_H	477_K	1.195	1.00
426_R	430_E	1.191	1.00
476_E	481_K	1.185	1.00
445_G	453_E	1.176	1.00
352_P	412_K	1.175	1.00
56_L	67_A	1.175	1.00
34_E	38_R	1.168	1.00
173_I	185_G	1.163	1.00
327_N	405_Y	1.159	1.00
87_P	91_G	1.158	1.00
454_A	486_A	1.157	1.00
222_F	262_A	1.151	1.00
26_M	256_Q	1.149	1.00
165_P	169_D	1.148	1.00
253_V	284_S	1.148	1.00
260_I	287_L	1.147	1.00
33_N	160_K	1.145	1.00
106_S	129_Q	1.141	1.00
365_L	408_I	1.137	1.00
414_D	426_R	1.131	1.00
357_L	361_Q	1.131	1.00
421_Y	482_Y	1.130	1.00
32_L	69_F	1.128	1.00
70_G	74_A	1.123	1.00
25_H	62_P	1.116	1.00
101_A	124_L	1.113	1.00
469_E	473_Q	1.112	1.00
273_Q	302_A	1.108	1.00
454_A	487_A	1.105	1.00
95_T	182_K	1.103	1.00
27_M	35_Y	1.100	1.00
19_A	29_Y	1.096	1.00
269_N	299_L	1.094	1.00
8_E	37_Q	1.089	1.00
57_L	90_I	1.087	1.00
247_A	274_H	1.085	1.00
168_D	189_T	1.084	1.00
176_T	186_A	1.079	1.00
35_Y	63_D	1.077	1.00
31_E	34_E	1.076	1.00
48_M	101_A	1.075	1.00
457_G	488_I	1.074	1.00
188_L	192_N	1.071	1.00
272_F	302_A	1.066	1.00
42_G	45_E	1.062	1.00
40_A	73_K	1.062	1.00
81_I	90_I	1.060	1.00
64_F	218_M	1.057	1.00
21_R	239_L	1.053	1.00
345_V	371_N	1.053	1.00
32_L	66_I	1.048	1.00
338_I	408_I	1.047	1.00
39_F	103_V	1.046	1.00
109_L	113_E	1.045	1.00
382_E	386_A	1.041	1.00
303_F	307_F	1.039	1.00
211_N	259_T	1.039	1.00
475_C	484_R	1.038	1.00
192_N	372_V	1.037	1.00
491_L	494_I	1.035	1.00
239_L	256_Q	1.034	1.00
366_I	391_W	1.032	1.00
415_M	424_Y	1.032	1.00
126_I	130_T	1.028	1.00
296_P	299_L	1.028	1.00
239_L	252_L	1.017	1.00
446_V	487_A	1.017	1.00
470_D	473_Q	1.015	1.00
461_P	466_V	1.015	1.00
435_H	471_I	1.013	1.00
431_V	434_S	1.009	1.00
439_K	460_V	1.009	1.00
210_D	236_A	1.005	1.00
89_E	483_K	1.002	1.00
212_V	231_P	1.002	1.00
216_L	222_F	0.999	1.00
494_I	502_M	0.995	1.00
419_G	451_S	0.995	1.00
367_V	394_T	0.994	1.00
505_R	509_D	0.984	1.00
302_A	306_K	0.980	1.00
27_M	32_L	0.979	1.00
429_E	504_R	0.976	1.00
36_I	70_G	0.972	1.00
52_D	76_I	0.969	1.00
480_A	483_K	0.969	1.00
18_I	28_T	0.965	1.00
325_C	406_F	0.964	1.00
58_L	128_C	0.963	1.00
186_A	373_M	0.963	1.00
23_K	242_P	0.963	1.00
327_N	337_S	0.962	1.00
42_G	156_T	0.960	1.00
369_G	372_V	0.959	1.00
53_H	98_D	0.958	1.00
442_V	494_I	0.956	1.00
416_I	455_V	0.954	1.00
468_E	488_I	0.951	1.00
88_T	478_H	0.948	1.00
85_Y	93_M	0.945	1.00
468_E	490_F	0.944	1.00
431_V	475_C	0.941	1.00
298_A	302_A	0.941	1.00
17_S	237_T	0.938	1.00
20_C	65_I	0.937	1.00
177_S	499_T	0.937	1.00
92_Y	95_T	0.936	1.00
41_D	157_S	0.933	1.00
34_E	158_A	0.930	1.00
92_Y	175_Y	0.929	1.00
347_N	406_F	0.929	1.00
24_D	255_Q	0.924	1.00
473_Q	476_E	0.924	1.00
195_S	370_P	0.923	1.00
43_L	71_A	0.922	1.00
270_Y	450_Q	0.920	1.00
82_N	219_F	0.913	1.00
351_D	361_Q	0.913	1.00
349_V	357_L	0.909	1.00
39_F	67_A	0.909	1.00
197_A	233_M	0.909	1.00
88_T	91_G	0.909	1.00
295_M	300_L	0.908	1.00
213_V	241_E	0.906	1.00
58_L	61_S	0.906	1.00
7_L	11_A	0.905	1.00
195_S	344_H	0.905	1.00
88_T	92_Y	0.904	1.00
62_P	66_I	0.899	1.00
55_A	102_I	0.898	1.00
196_N	322_P	0.898	1.00
231_P	238_V	0.896	1.00
68_F	78_V	0.894	1.00
435_H	470_D	0.893	1.00
397_L	410_D	0.893	1.00
347_N	365_L	0.892	1.00
174_L	318_S	0.892	1.00
269_N	296_P	0.891	1.00
46_A	101_A	0.888	1.00
334_K	401_D	0.887	1.00
25_H	35_Y	0.884	1.00
434_S	474_H	0.883	1.00
44_Q	161_Q	0.881	1.00
268_Y	303_F	0.879	1.00
32_L	36_I	0.879	1.00
418_V	445_G	0.876	1.00
388_K	393_Y	0.875	1.00
44_Q	49_E	0.874	1.00
302_A	305_E	0.872	1.00
108_L	111_L	0.870	1.00
349_V	406_F	0.868	1.00
287_L	312_L	0.867	1.00
41_D	44_Q	0.864	1.00
21_R	211_N	0.864	1.00
56_L	78_V	0.864	1.00
188_L	321_S	0.863	1.00
470_D	474_H	0.860	1.00
63_D	66_I	0.857	1.00
105_V	108_L	0.856	1.00
244_F	267_M	0.856	1.00
59_G	107_Q	0.853	1.00
209_R	259_T	0.847	1.00
41_D	161_Q	0.846	1.00
387_L	393_Y	0.841	1.00
337_S	405_Y	0.840	1.00
40_A	74_A	0.837	1.00
354_G	366_I	0.836	1.00
31_E	35_Y	0.833	1.00
43_L	103_V	0.832	1.00
92_Y	379_M	0.831	1.00
9_E	12_S	0.830	1.00
221_V	317_L	0.830	1.00
33_N	36_I	0.827	1.00
71_A	78_V	0.824	1.00
48_M	74_A	0.824	1.00
262_A	323_V	0.823	1.00
171_A	190_H	0.821	1.00
68_F	224_L	0.819	1.00
188_L	373_M	0.817	1.00
20_C	62_P	0.816	1.00
65_I	240_I	0.812	1.00
8_E	12_S	0.812	1.00
447_P	450_Q	0.810	1.00
55_A	79_V	0.805	1.00
365_L	406_F	0.804	1.00
254_K	281_D	0.804	1.00
211_N	257_Q	0.801	1.00
289_I	314_G	0.794	1.00
221_V	322_P	0.794	1.00
360_H	402_E	0.793	1.00
471_I	488_I	0.792	1.00
6_K	198_N	0.791	1.00
259_T	286_R	0.790	1.00
110_P	113_E	0.787	1.00
17_S	208_E	0.784	1.00
35_Y	62_P	0.784	1.00
165_P	190_H	0.782	1.00
352_P	364_E	0.781	1.00
442_V	507_L	0.780	1.00
7_L	69_F	0.777	1.00
66_I	70_G	0.774	1.00
287_L	310_T	0.773	1.00
320_A	372_V	0.773	1.00
18_I	22_F	0.772	1.00
460_V	493_D	0.771	1.00
170_T	189_T	0.768	1.00
381_M	384_E	0.768	1.00
437_D	462_K	0.768	1.00
215_A	267_M	0.765	1.00
206_M	210_D	0.763	1.00
418_V	486_A	0.763	1.00
348_K	389_D	0.763	1.00
247_A	251_K	0.761	1.00
264_V	267_M	0.757	1.00
268_Y	290_S	0.756	1.00
383_T	387_L	0.753	1.00
346_E	391_W	0.749	1.00
320_A	392_L	0.748	1.00
5_S	8_E	0.748	1.00
414_D	429_E	0.748	1.00
25_H	63_D	0.746	1.00
379_M	383_T	0.745	1.00
32_L	65_I	0.745	1.00
275_E	279_K	0.745	1.00
68_F	72_L	0.744	1.00
6_K	10_T	0.743	1.00
71_A	74_A	0.742	1.00
347_N	398_A	0.742	1.00
88_T	182_K	0.742	1.00
58_L	64_F	0.740	1.00
398_A	406_F	0.739	1.00
472_M	484_R	0.738	1.00
106_S	130_T	0.737	1.00
320_A	367_V	0.736	1.00
66_I	149_F	0.736	1.00
38_R	42_G	0.736	1.00
269_N	302_A	0.736	1.00
93_M	185_G	0.735	1.00
225_T	262_A	0.733	1.00
269_N	273_Q	0.733	1.00
447_P	452_G	0.731	1.00
362_V	412_K	0.729	1.00
171_A	193_L	0.729	1.00
418_V	455_V	0.724	1.00
7_L	33_N	0.724	1.00
79_V	99_V	0.723	1.00
432_L	441_A	0.723	1.00
447_P	451_S	0.718	1.00
468_E	472_M	0.718	1.00
24_D	256_Q	0.716	1.00
350_V	356_E	0.715	1.00
206_M	260_I	0.714	1.00
222_F	291_G	0.713	1.00
251_K	254_K	0.713	1.00
393_Y	412_K	0.712	1.00
348_K	368_K	0.712	1.00
172_V	188_L	0.712	1.00
61_S	105_V	0.711	1.00
220_H	421_Y	0.709	1.00
442_V	502_M	0.708	1.00
285_I	288_C	0.706	1.00
5_S	9_E	0.705	1.00
38_R	157_S	0.705	1.00
26_M	237_T	0.704	1.00
320_A	324_T	0.704	1.00
78_V	224_L	0.702	1.00
481_K	484_R	0.702	1.00
248_S	252_L	0.702	1.00
57_L	102_I	0.701	1.00
298_A	301_T	0.699	1.00
57_L	108_L	0.698	1.00
312_L	328_P	0.696	1.00
431_V	474_H	0.696	1.00
44_Q	163_Q	0.696	1.00
196_N	321_S	0.694	1.00
49_E	76_I	0.694	1.00
253_V	258_A	0.693	1.00
437_D	461_P	0.692	1.00
207_D	286_R	0.692	1.00
444_I	508_R	0.692	1.00
280_D	283_S	0.692	1.00
295_M	311_I	0.690	1.00
196_N	225_T	0.690	1.00
102_I	112_Y	0.689	1.00
55_A	97_G	0.686	1.00
446_V	454_A	0.685	1.00
314_G	323_V	0.685	1.00
426_R	429_E	0.684	1.00
213_V	252_L	0.684	1.00
38_R	158_A	0.683	1.00
40_A	70_G	0.682	1.00
67_A	71_A	0.682	1.00
214_C	227_C	0.679	1.00
201_A	230_A	0.679	1.00
16_D	28_T	0.679	1.00
241_E	249_V	0.679	1.00
475_C	479_L	0.677	1.00
262_A	314_G	0.677	1.00
439_K	461_P	0.676	1.00
111_L	114_S	0.672	1.00
49_E	100_K	0.672	1.00
39_F	43_L	0.671	1.00
54_L	101_A	0.671	1.00
14_K	30_Q	0.670	1.00
359_A	402_E	0.670	1.00
41_D	156_T	0.666	1.00
68_F	229_N	0.666	1.00
10_T	235_G	0.655	1.00
459_V	471_I	0.653	1.00
50_K	163_Q	0.652	1.00
372_V	392_L	0.652	1.00
351_D	354_G	0.651	1.00
192_N	374_K	0.651	1.00
39_F	42_G	0.649	1.00
104_G	125_V	0.648	1.00
104_G	127_L	0.648	1.00
278_K	306_K	0.648	1.00
44_Q	160_K	0.647	1.00
168_D	374_K	0.647	1.00
22_F	242_P	0.645	1.00
288_C	303_F	0.645	1.00
269_N	298_A	0.645	1.00
398_A	409_V	0.640	1.00
41_D	158_A	0.639	1.00
160_K	163_Q	0.638	1.00
50_K	165_P	0.638	1.00
212_V	260_I	0.638	1.00
253_V	261_F	0.637	1.00
11_A	15_P	0.636	1.00
213_V	253_V	0.636	1.00
261_F	288_C	0.636	1.00
58_L	103_V	0.635	1.00
86_T	89_E	0.631	1.00
313_E	336_G	0.630	1.00
196_N	323_V	0.630	1.00
342_I	345_V	0.630	1.00
104_G	109_L	0.629	1.00
349_V	400_R	0.627	1.00
425_P	504_R	0.627	1.00
315_Y	324_T	0.627	1.00
37_Q	160_K	0.626	1.00
442_V	504_R	0.625	1.00
425_P	443_V	0.624	1.00
6_K	194_Y	0.624	1.00
438_V	459_V	0.623	1.00
98_D	377_Y	0.623	1.00
27_M	31_E	0.622	1.00
458_Y	489_T	0.621	1.00
104_G	108_L	0.621	1.00
448_D	451_S	0.620	1.00
96_N	377_Y	0.619	1.00
182_K	379_M	0.619	1.00
304_E	310_T	0.619	1.00
244_F	249_V	0.618	1.00
317_L	320_A	0.618	1.00
69_F	229_N	0.618	1.00
14_K	235_G	0.616	1.00
203_Y	343_L	0.616	1.00
41_D	159_A	0.615	1.00
37_Q	159_A	0.615	1.00
254_K	284_S	0.614	1.00
251_K	280_D	0.614	1.00
225_T	322_P	0.613	1.00
227_C	262_A	0.609	1.00
495_P	507_L	0.608	1.00
14_K	208_E	0.608	1.00
472_M	475_C	0.608	1.00
206_M	236_A	0.608	1.00
453_E	508_R	0.607	1.00
215_A	264_V	0.606	1.00
36_I	39_F	0.604	1.00
112_Y	115_M	0.604	1.00
279_K	282_F	0.604	1.00
373_M	386_A	0.603	1.00
418_V	451_S	0.603	1.00
58_L	67_A	0.603	1.00
20_C	238_V	0.603	1.00
41_D	160_K	0.602	1.00
466_V	471_I	0.601	1.00
36_I	40_A	0.601	1.00
53_H	378_K	0.600	1.00
252_L	255_Q	0.600	1.00
45_E	155_P	0.599	1.00
431_V	479_L	0.598	1.00
249_V	253_V	0.598	1.00
151_K	154_R	0.597	1.00
225_T	323_V	0.597	1.00
12_S	33_N	0.596	1.00
439_K	463_R	0.596	1.00
79_V	175_Y	0.596	1.00
58_L	105_V	0.595	1.00
304_E	331_R	0.595	1.00
317_L	394_T	0.594	1.00
299_L	302_A	0.594	1.00
44_Q	162_N	0.593	1.00
198_N	233_M	0.593	1.00
77_V	173_I	0.592	1.00
101_A	126_I	0.591	1.00
63_D	105_V	0.591	1.00
197_A	229_N	0.591	1.00
216_L	262_A	0.591	1.00
379_M	385_H	0.590	1.00
338_I	398_A	0.588	1.00
413_K	453_E	0.588	1.00
47_G	76_I	0.587	1.00
80_P	174_L	0.586	1.00
172_V	224_L	0.585	1.00
57_L	111_L	0.585	1.00
68_F	228_M	0.584	1.00
254_K	283_S	0.583	1.00
438_V	441_A	0.583	1.00
349_V	365_L	0.581	1.00
469_E	472_M	0.581	1.00
29_Y	236_A	0.581	1.00
375_G	380_P	0.580	1.00
301_T	304_E	0.579	1.00
215_A	263_G	0.578	1.00
214_C	238_V	0.578	1.00
6_K	233_M	0.578	1.00
96_N	185_G	0.578	1.00
57_L	112_Y	0.577	1.00
237_T	256_Q	0.575	1.00
432_L	475_C	0.574	1.00
356_E	366_I	0.574	1.00
58_L	104_G	0.574	1.00
262_A	291_G	0.573	1.00
153_L	156_T	0.571	1.00
172_V	193_L	0.571	1.00
104_G	112_Y	0.570	1.00
18_I	211_N	0.569	1.00
275_E	278_K	0.569	1.00
360_H	399_R	0.568	1.00
430_E	434_S	0.566	1.00
43_L	101_A	0.565	1.00
350_V	391_W	0.564	1.00
173_I	187_M	0.563	1.00
196_N	200_V	0.563	1.00
169_D	190_H	0.562	1.00
77_V	377_Y	0.562	1.00
41_D	45_E	0.560	1.00
440_E	494_I	0.559	1.00
89_E	427_E	0.559	1.00
21_R	24_D	0.558	1.00
301_T	335_P	0.558	1.00
425_P	445_G	0.557	1.00
219_F	421_Y	0.557	1.00
56_L	71_A	0.557	1.00
295_M	313_E	0.554	1.00
217_P	220_H	0.553	1.00
113_E	116_H	0.552	1.00
428_V	455_V	0.551	1.00
294_S	408_I	0.550	1.00
106_S	127_L	0.549	1.00
356_E	400_R	0.548	1.00
37_Q	44_Q	0.548	1.00
39_F	149_F	0.547	1.00
53_H	99_V	0.547	1.00
416_I	445_G	0.546	1.00
97_G	185_G	0.546	1.00
56_L	64_F	0.545	1.00
35_Y	39_F	0.544	1.00
314_G	326_F	0.543	1.00
290_S	311_I	0.542	1.00
181_G	424_Y	0.542	1.00
325_C	338_I	0.541	1.00
222_F	289_I	0.541	1.00
38_R	41_D	0.540	1.00
211_N	214_C	0.540	1.00
429_E	457_G	0.540	1.00
198_N	201_A	0.540	1.00
380_P	383_T	0.539	1.00
446_V	458_Y	0.538	1.00
290_S	313_E	0.538	1.00
270_Y	273_Q	0.538	1.00
42_G	153_L	0.538	1.00
127_L	130_T	0.537	1.00
487_A	490_F	0.535	1.00
435_H	438_V	0.533	1.00
291_G	314_G	0.532	1.00
214_C	240_I	0.532	1.00
43_L	76_I	0.532	1.00
367_V	372_V	0.531	1.00
81_I	94_L	0.529	1.00
484_R	488_I	0.527	1.00
199_D	203_Y	0.527	1.00
250_F	282_F	0.527	1.00
303_F	311_I	0.527	1.00
265_P	293_A	0.526	1.00
441_A	475_C	0.525	1.00
48_M	100_K	0.525	1.00
200_V	225_T	0.525	1.00
437_D	474_H	0.524	1.00
430_E	433_Y	0.523	1.00
418_V	453_E	0.521	1.00
291_G	323_V	0.520	1.00
7_L	36_I	0.520	1.00
213_V	249_V	0.519	1.00
97_G	173_I	0.518	1.00
327_N	330_D	0.518	1.00
20_C	27_M	0.517	1.00
29_Y	232_L	0.516	1.00
77_V	80_P	0.516	1.00
206_M	230_A	0.516	1.00
35_Y	153_L	0.515	1.00
250_F	271_L	0.515	1.00
401_D	404_G	0.514	1.00
493_D	496_K	0.513	1.00
109_L	127_L	0.512	1.00
222_F	314_G	0.512	1.00
212_V	236_A	0.512	1.00
5_S	164_E	0.510	1.00
410_D	425_P	0.510	1.00
214_C	223_C	0.510	1.00
85_Y	90_I	0.509	1.00
505_R	508_R	0.509	1.00
387_L	392_L	0.509	1.00
259_T	284_S	0.509	1.00
203_Y	328_P	0.508	1.00
20_C	32_L	0.508	1.00
38_R	156_T	0.508	1.00
125_V	128_C	0.507	1.00
149_F	153_L	0.507	1.00
76_I	101_A	0.507	1.00
324_T	345_V	0.506	1.00
288_C	309_V	0.503	1.00
361_Q	399_R	0.503	1.00
180_T	184_K	0.501	1.00
52_D	101_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1mdbA	1	0.9708	100	0.089	Contact Map
3tsyA	2	0.7914	100	0.092	Contact Map
3etcA	2	0.9435	100	0.094	Contact Map
3g7sA	2	0.8928	100	0.096	Contact Map
3o83A	1	0.7836	100	0.097	Contact Map
3ni2A	1	0.9688	100	0.104	Contact Map
2d1sA	1	0.9786	100	0.106	Contact Map
1v25A	2	0.9201	100	0.109	Contact Map
4iz6A	2	0.9688	100	0.112	Contact Map
2v7bA	1	0.9396	100	0.113	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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