GREMLIN Database
YHJR - Uncharacterized protein YhjR
UniProt: O07572 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 145 (131)
Sequences: 221 (182)
Seq/√Len: 15.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_L93_G3.9661.00
29_E131_E3.4720.99
36_Y101_E2.7000.97
98_F142_L2.5060.95
90_F94_L2.3180.92
122_G125_T2.1910.90
59_E134_H2.1600.89
48_V90_F2.1060.88
133_N137_W2.1030.88
22_L73_I2.0850.87
94_L141_Y2.0310.86
123_V127_A1.9960.85
55_I87_P1.9260.82
106_D133_N1.9120.82
65_E123_V1.8990.81
59_E104_T1.8900.81
25_A66_F1.8640.80
55_I133_N1.8550.80
132_Q136_V1.8350.79
62_H130_D1.8050.78
102_Q106_D1.7800.77
84_E87_P1.7580.76
124_F127_A1.5950.69
45_S48_V1.5720.67
30_F34_Q1.5490.66
124_F128_A1.5480.66
47_E99_K1.5320.65
43_A90_F1.5150.64
18_L115_T1.4970.63
109_L126_R1.4120.59
32_A100_D1.3410.55
136_V139_L1.3390.55
44_H118_L1.3080.53
47_E95_D1.2880.52
115_T124_F1.2860.52
41_E45_S1.2780.51
113_E126_R1.2770.51
71_G77_H1.2760.51
56_R87_P1.2690.51
58_D130_D1.2440.49
106_D137_W1.2390.49
90_F141_Y1.2350.49
58_D134_H1.1920.46
130_D134_H1.1900.46
58_D135_A1.1840.46
37_R41_E1.1520.44
75_G93_G1.1320.43
42_L90_F1.1300.43
29_E32_A1.1070.41
106_D122_G1.0930.41
62_H134_H1.0810.40
49_R85_E1.0750.40
63_L142_L1.0730.39
33_I63_L1.0710.39
125_T128_A1.0680.39
103_E141_Y1.0680.39
29_E66_F1.0640.39
55_I134_H1.0510.38
102_Q135_A1.0510.38
59_E62_H1.0500.38
37_R64_R1.0400.38
28_G101_E1.0340.37
30_F63_L1.0330.37
66_F131_E1.0300.37
24_K61_R1.0280.37
38_K84_E1.0270.37
14_E76_K1.0160.36
16_P41_E1.0070.36
54_E133_N1.0000.35
102_Q137_W0.9990.35
25_A32_A0.9910.35
18_L114_E0.9800.34
104_T130_D0.9730.34
50_K53_E0.9590.33
19_I123_V0.9560.33
91_T142_L0.9500.33
57_R89_N0.9500.33
35_C109_L0.9290.32
45_S67_S0.9260.32
41_E92_R0.9230.31
35_C106_D0.9220.31
20_R95_D0.9210.31
29_E101_E0.9110.31
20_R61_R0.9110.31
29_E108_Y0.9100.31
25_A134_H0.9070.31
22_L109_L0.8990.30
132_Q139_L0.8990.30
52_I135_A0.8970.30
76_K103_E0.8960.30
23_Q78_I0.8950.30
110_R122_G0.8940.30
47_E92_R0.8770.29
64_R68_T0.8760.29
45_S68_T0.8690.29
47_E51_Q0.8560.28
30_F33_I0.8540.28
35_C86_C0.8530.28
102_Q109_L0.8480.28
26_I106_D0.8480.28
39_L90_F0.8360.27
16_P125_T0.8330.27
69_L120_A0.8260.27
64_R103_E0.8220.27
46_D50_K0.8160.26
104_T140_Y0.8130.26
35_C104_T0.8000.26
128_A132_Q0.7920.25
102_Q139_L0.7920.25
27_N78_I0.7860.25
14_E122_G0.7830.25
71_G123_V0.7810.25
26_I115_T0.7760.25
63_L80_P0.7740.25
125_T129_R0.7710.24
52_I66_F0.7640.24
88_D121_K0.7640.24
72_S128_A0.7620.24
89_N92_R0.7600.24
57_R79_M0.7600.24
42_L89_N0.7500.24
22_L69_L0.7420.23
28_G59_E0.7420.23
33_I97_A0.7420.23
121_K125_T0.7360.23
112_A125_T0.7340.23
22_L76_K0.7320.23
28_G66_F0.7310.23
49_R88_D0.7290.23
55_I137_W0.7220.22
33_I60_I0.7170.22
24_K53_E0.7080.22
21_N107_F0.7060.22
28_G104_T0.7010.22
59_E130_D0.6980.21
59_E100_D0.6940.21
112_A121_K0.6850.21
53_E57_R0.6830.21
86_C132_Q0.6830.21
125_T133_N0.6780.21
109_L113_E0.6770.21
28_G36_Y0.6700.20
107_F128_A0.6640.20
128_A137_W0.6610.20
107_F138_F0.6590.20
82_Q116_S0.6580.20
71_G78_I0.6540.20
22_L111_A0.6480.20
56_R60_I0.6450.19
50_K90_F0.6430.19
22_L77_H0.6390.19
51_Q141_Y0.6360.19
73_I122_G0.6360.19
92_R123_V0.6330.19
80_P98_F0.6290.19
78_I95_D0.6290.19
43_A70_Y0.6280.19
55_I138_F0.6260.19
32_A138_F0.6230.19
12_Y88_D0.6220.19
61_R126_R0.6200.19
21_N129_R0.6150.18
35_C134_H0.6090.18
112_A122_G0.6040.18
25_A59_E0.5980.18
56_R59_E0.5940.18
87_P93_G0.5880.17
62_H108_Y0.5870.17
78_I103_E0.5810.17
19_I79_M0.5740.17
68_T85_E0.5690.17
78_I133_N0.5660.17
101_E104_T0.5640.17
45_S95_D0.5630.17
87_P94_L0.5590.17
76_K88_D0.5520.16
44_H90_F0.5520.16
63_L105_V0.5510.16
49_R129_R0.5490.16
16_P45_S0.5450.16
14_E116_S0.5430.16
113_E128_A0.5410.16
52_I138_F0.5400.16
79_M98_F0.5380.16
14_E142_L0.5340.16
54_E58_D0.5320.16
34_Q38_K0.5320.16
29_E36_Y0.5240.15
71_G115_T0.5230.15
74_T131_E0.5230.15
98_F102_Q0.5150.15
111_A130_D0.5080.15
85_E96_A0.5060.15
32_A101_E0.5040.15
50_K89_N0.5030.15
109_L129_R0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2fzfA 2 0.9517 99.6 0.663 Contact Map
1vjxA 1 0.9172 99.5 0.668 Contact Map
2oh3A 2 0.8828 99.5 0.68 Contact Map
4etrA 1 0.8276 99.2 0.729 Contact Map
4di0A 2 0.9034 99.1 0.733 Contact Map
4am5A 6 0.9241 99.1 0.74 Contact Map
1j30A 5 0.9034 99 0.746 Contact Map
3qhbA 1 1 99 0.747 Contact Map
1yuzA 2 1 98.9 0.752 Contact Map
1lkoA 3 0.9103 98.9 0.752 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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