GREMLIN Database
YHJN - Uncharacterized protein YhjN
UniProt: O07568 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 384 (337)
Sequences: 1092 (871)
Seq/√Len: 47.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
141_A151_V5.1171.00
217_A222_F4.7171.00
95_S346_V3.9481.00
213_A229_G3.6661.00
21_G33_W3.6391.00
301_L305_I3.6221.00
13_F41_A3.3791.00
262_Q328_E3.2841.00
17_S267_A3.2351.00
34_M162_V3.1311.00
146_A151_V2.8461.00
31_I328_E2.8431.00
78_G234_V2.7451.00
234_V238_H2.7411.00
215_K219_F2.6981.00
20_G37_T2.6831.00
38_L269_I2.5651.00
236_I240_G2.4811.00
326_I351_V2.3631.00
22_F26_L2.3371.00
101_I290_V2.3341.00
333_S343_V2.3161.00
121_D124_T2.2831.00
312_I317_S2.2591.00
213_A217_A2.2571.00
110_S291_S2.2191.00
213_A233_G2.2071.00
137_M358_L2.1621.00
136_A262_Q2.1461.00
313_S316_T2.1241.00
364_L368_L2.1221.00
262_Q327_A2.1201.00
133_G262_Q2.0901.00
17_S20_G2.0721.00
43_C47_I2.0100.99
128_G154_V1.9950.99
359_P362_Y1.9840.99
21_G263_V1.9530.99
276_S347_Q1.9000.99
204_V208_L1.8790.99
304_V308_E1.8780.99
31_I262_Q1.8330.99
201_L233_G1.8230.99
162_V324_G1.8040.99
13_F17_S1.8020.99
113_V117_F1.7750.99
74_G227_L1.7390.98
136_A328_E1.7310.98
35_I39_I1.7190.98
102_L347_Q1.7120.98
227_L265_L1.6680.98
321_F346_V1.6400.98
16_I44_L1.6280.98
168_F172_L1.5900.97
99_M103_S1.5860.97
329_M343_V1.5850.97
236_I239_V1.5790.97
116_R219_F1.5790.97
134_L322_A1.5760.97
260_V289_F1.5610.97
261_S295_L1.5530.97
76_E225_P1.5460.97
363_R367_H1.5430.97
133_G328_E1.5360.96
13_F159_V1.5340.96
29_I32_G1.5320.96
279_A283_R1.5310.96
127_V331_T1.5230.96
328_E331_T1.4970.96
81_L269_I1.4930.96
23_I26_L1.4920.96
12_W216_A1.4710.95
340_S343_V1.4700.95
307_S314_L1.4510.95
133_G327_A1.4380.95
262_Q331_T1.4290.95
112_Y261_S1.4280.95
27_T289_F1.4060.94
167_P262_Q1.4040.94
204_V337_H1.3870.94
215_K218_K1.3870.94
30_S250_T1.3860.94
31_I327_A1.3850.94
29_I176_K1.3770.94
24_L39_I1.3760.94
313_S320_A1.3710.93
34_M342_F1.3650.93
154_V159_V1.3610.93
341_T361_F1.3520.93
24_L35_I1.3500.93
80_K340_S1.3460.93
133_G351_V1.3460.93
115_W122_M1.3320.92
127_V362_Y1.3220.92
133_G265_L1.3190.92
93_W133_G1.3190.92
141_A148_T1.3180.92
217_A294_G1.2960.91
222_F229_G1.2930.91
339_D359_P1.2880.91
39_I164_L1.2850.91
107_A347_Q1.2620.90
111_G321_F1.2550.90
17_S41_A1.2290.89
124_T146_A1.2290.89
11_L15_A1.2100.88
94_F294_G1.2100.88
70_Q344_V1.2050.88
142_Q148_T1.2040.88
329_M336_L1.2000.88
33_W163_V1.1990.88
305_I361_F1.1820.87
107_A137_M1.1820.87
24_L32_G1.1780.87
161_L289_F1.1740.87
31_I34_M1.1730.87
35_I142_Q1.1680.86
143_E260_V1.1610.86
19_A22_F1.1570.86
33_W328_E1.1570.86
111_G155_Q1.1530.86
205_I236_I1.1530.86
11_L60_G1.1520.86
123_M153_L1.1520.86
137_M354_V1.1490.85
20_G24_L1.1430.85
33_W319_L1.1300.84
23_I101_I1.1210.84
115_W125_S1.1200.84
45_A149_A1.1190.84
198_A203_T1.1180.84
137_M322_A1.1110.83
74_G78_G1.1100.83
166_I318_V1.1090.83
212_G236_I1.1070.83
297_A301_L1.1040.83
107_A343_V1.1040.83
237_V241_G1.0950.83
96_V343_V1.0890.82
153_L288_G1.0860.82
46_M352_I1.0830.82
78_G262_Q1.0730.81
74_G132_G1.0700.81
25_S33_W1.0640.81
21_G175_T1.0630.81
128_G281_V1.0620.81
73_L77_L1.0600.80
118_S287_V1.0600.80
269_I339_D1.0550.80
232_L365_L1.0520.80
106_L298_A1.0520.80
156_M318_V1.0500.80
16_I29_I1.0490.80
227_L325_G1.0450.79
62_N98_V1.0450.79
307_S332_T1.0440.79
182_S216_A1.0380.79
128_G317_S1.0350.79
160_L239_V1.0320.79
9_K19_A1.0200.78
113_V290_V1.0180.78
136_A327_A1.0150.77
103_S147_N1.0140.77
81_L353_L1.0080.77
310_T317_S1.0030.77
157_M285_I0.9990.76
9_K59_K0.9960.76
275_K347_Q0.9880.75
21_G169_L0.9870.75
18_A22_F0.9870.75
21_G25_S0.9860.75
334_V347_Q0.9860.75
352_I356_A0.9850.75
40_V44_L0.9800.75
69_G264_F0.9750.75
105_L289_F0.9740.74
181_A208_L0.9710.74
19_A68_L0.9710.74
31_I141_A0.9700.74
133_G136_A0.9670.74
124_T128_G0.9550.73
62_N155_Q0.9550.73
73_L287_V0.9520.73
347_Q351_V0.9480.72
102_L155_Q0.9470.72
70_Q136_A0.9460.72
19_A297_A0.9460.72
68_L297_A0.9450.72
65_W139_S0.9440.72
120_T303_A0.9430.72
66_L330_A0.9420.72
108_M332_T0.9410.72
161_L164_L0.9330.71
152_S338_A0.9290.71
325_G355_I0.9220.70
10_D13_F0.9220.70
19_A177_Q0.9210.70
222_F235_A0.9120.69
82_N131_P0.9050.69
92_H342_F0.9040.69
29_I97_G0.9020.69
327_A332_T0.9000.68
159_V163_V0.8910.68
64_R236_I0.8910.68
66_L99_M0.8900.68
159_V327_A0.8870.67
214_C217_A0.8860.67
128_G166_I0.8830.67
38_L340_S0.8790.67
130_A137_M0.8770.66
19_A308_E0.8770.66
218_K237_V0.8770.66
299_M322_A0.8760.66
304_V309_L0.8760.66
156_M332_T0.8680.66
208_L212_G0.8680.66
106_L135_S0.8660.65
155_Q262_Q0.8650.65
63_R98_V0.8640.65
123_M128_G0.8620.65
40_V101_I0.8580.65
141_A175_T0.8570.65
21_G343_V0.8520.64
155_Q166_I0.8510.64
138_P342_F0.8490.64
317_S359_P0.8480.64
133_G167_P0.8480.64
45_A157_M0.8470.64
209_A233_G0.8440.63
87_S294_G0.8440.63
17_S37_T0.8400.63
105_L201_L0.8400.63
9_K22_F0.8380.63
195_F207_I0.8310.62
65_W264_F0.8290.62
114_L347_Q0.8230.61
75_I222_F0.8220.61
161_L296_I0.8210.61
211_W215_K0.8210.61
154_V288_G0.8210.61
70_Q326_I0.8200.61
307_S318_V0.8160.61
13_F20_G0.8130.61
101_I208_L0.8100.60
18_A28_G0.8090.60
260_V298_A0.8030.60
33_W259_H0.7960.59
147_N217_A0.7960.59
289_F363_R0.7950.59
73_L96_V0.7940.59
130_A354_V0.7890.58
15_A177_Q0.7860.58
71_M210_A0.7850.58
92_H95_S0.7830.58
133_G325_G0.7830.58
137_M146_A0.7830.58
135_S331_T0.7790.57
86_L90_K0.7770.57
69_G73_L0.7750.57
288_G343_V0.7740.57
81_L168_F0.7720.57
30_S266_G0.7670.56
278_F352_I0.7670.56
279_A282_T0.7650.56
33_W343_V0.7640.56
70_Q316_T0.7610.55
28_G222_F0.7600.55
71_M214_C0.7600.55
224_A334_V0.7580.55
21_G37_T0.7580.55
163_V327_A0.7530.55
153_L277_M0.7500.54
145_G311_G0.7500.54
99_M126_F0.7500.54
29_I101_I0.7500.54
59_K271_S0.7490.54
24_L222_F0.7480.54
34_M152_S0.7470.54
212_G218_K0.7450.54
153_L163_V0.7440.54
282_T286_I0.7440.54
114_L272_K0.7420.54
100_L103_S0.7390.53
15_A180_T0.7380.53
36_G269_I0.7380.53
16_I169_L0.7380.53
319_L340_S0.7370.53
114_L287_V0.7320.53
111_G127_V0.7310.52
192_T204_V0.7300.52
200_V204_V0.7290.52
262_Q351_V0.7290.52
155_Q173_I0.7290.52
39_I87_S0.7280.52
249_M364_L0.7260.52
109_L260_V0.7260.52
71_M170_V0.7260.52
78_G167_P0.7230.52
204_V212_G0.7200.51
165_S368_L0.7200.51
88_V91_D0.7200.51
127_V146_A0.7190.51
103_S224_A0.7180.51
111_G316_T0.7180.51
166_I320_A0.7170.51
86_L364_L0.7170.51
320_A340_S0.7100.50
150_I227_L0.7090.50
40_V113_V0.7090.50
12_W194_D0.7090.50
298_A302_S0.7080.50
12_W44_L0.7080.50
9_K50_A0.7060.50
32_G66_L0.7050.50
107_A159_V0.7010.49
93_W325_G0.7000.49
212_G219_F0.6970.49
300_F314_L0.6960.49
27_T86_L0.6960.49
127_V273_M0.6920.49
146_A252_W0.6920.49
316_T338_A0.6920.49
102_L229_G0.6910.48
114_L331_T0.6910.48
215_K225_P0.6900.48
216_A339_D0.6860.48
289_F293_V0.6830.48
139_S309_L0.6830.48
315_I336_L0.6830.48
222_F225_P0.6820.48
128_G239_V0.6790.47
104_I348_V0.6780.47
107_A354_V0.6740.47
116_R240_G0.6720.47
81_L331_T0.6720.47
224_A326_I0.6720.47
318_V336_L0.6690.46
96_V346_V0.6680.46
78_G288_G0.6680.46
33_W159_V0.6680.46
293_V301_L0.6670.46
232_L357_L0.6650.46
130_A358_L0.6650.46
125_S174_Y0.6620.46
144_V151_V0.6620.46
237_V242_A0.6600.45
235_A239_V0.6600.45
200_V260_V0.6580.45
93_W97_G0.6570.45
11_L308_E0.6570.45
86_L113_V0.6530.45
166_I268_T0.6530.45
206_L225_P0.6530.45
11_L193_T0.6520.45
15_A293_V0.6520.45
70_Q135_S0.6500.44
269_I327_A0.6480.44
31_I347_Q0.6470.44
299_M354_V0.6460.44
293_V297_A0.6440.44
19_A49_P0.6440.44
137_M296_I0.6430.44
95_S342_F0.6390.43
70_Q92_H0.6390.43
67_A135_S0.6380.43
81_L330_A0.6350.43
294_G305_I0.6350.43
121_D145_G0.6330.43
105_L235_A0.6320.43
159_V334_V0.6300.42
137_M162_V0.6290.42
97_G305_I0.6280.42
176_K216_A0.6280.42
86_L285_I0.6260.42
322_A329_M0.6220.42
97_G236_I0.6190.41
15_A297_A0.6180.41
141_A172_L0.6160.41
107_A133_G0.6150.41
269_I329_M0.6130.41
35_I274_Y0.6130.41
272_K353_L0.6110.41
235_A349_I0.6110.41
131_P269_I0.6110.41
233_G312_I0.6090.40
20_G41_A0.6070.40
156_M322_A0.6060.40
85_V291_S0.6010.40
293_V309_L0.6010.40
147_N222_F0.6000.40
303_A314_L0.6000.40
124_T133_G0.5990.39
45_A227_L0.5990.39
194_D207_I0.5990.39
116_R199_P0.5990.39
272_K292_S0.5990.39
288_G321_F0.5990.39
141_A145_G0.5980.39
17_S329_M0.5960.39
103_S275_K0.5960.39
71_M269_I0.5950.39
101_I233_G0.5950.39
87_S208_L0.5940.39
80_K153_L0.5940.39
97_G352_I0.5930.39
126_F288_G0.5900.39
70_Q214_C0.5900.39
306_V315_I0.5900.39
62_N352_I0.5890.39
24_L92_H0.5890.39
75_I234_V0.5880.38
65_W204_V0.5840.38
268_T271_S0.5840.38
128_G136_A0.5830.38
225_P355_I0.5830.38
199_P305_I0.5820.38
40_V43_C0.5820.38
327_A354_V0.5820.38
201_L212_G0.5810.38
268_T272_K0.5810.38
310_T341_T0.5810.38
80_K234_V0.5770.37
34_M148_T0.5760.37
144_V303_A0.5750.37
90_K94_F0.5750.37
172_L352_I0.5710.37
126_F362_Y0.5670.36
155_Q351_V0.5670.36
96_V224_A0.5660.36
47_I180_T0.5650.36
71_M209_A0.5650.36
82_N265_L0.5640.36
317_S347_Q0.5640.36
200_V360_P0.5620.36
114_L118_S0.5610.36
144_V338_A0.5610.36
288_G341_T0.5560.35
326_I348_V0.5550.35
109_L220_L0.5530.35
24_L313_S0.5500.35
87_S209_A0.5490.35
156_M330_A0.5480.35
131_P354_V0.5480.35
236_I293_V0.5470.35
22_F297_A0.5460.35
102_L107_A0.5460.35
87_S116_R0.5450.34
22_F43_C0.5440.34
23_I178_D0.5440.34
167_P328_E0.5430.34
141_A319_L0.5420.34
68_L72_I0.5410.34
119_K122_M0.5410.34
95_S321_F0.5410.34
98_V311_G0.5400.34
46_M263_V0.5390.34
72_I368_L0.5370.34
107_A265_L0.5360.34
155_Q352_I0.5360.34
212_G215_K0.5360.34
107_A352_I0.5350.34
98_V290_V0.5330.33
23_I290_V0.5330.33
327_A331_T0.5330.33
139_S261_S0.5320.33
32_G262_Q0.5310.33
64_R260_V0.5300.33
202_W212_G0.5300.33
15_A246_G0.5290.33
133_G295_L0.5280.33
235_A352_I0.5260.33
204_V308_E0.5250.33
13_F129_T0.5250.33
140_I341_T0.5250.33
305_I308_E0.5230.32
304_V307_S0.5230.32
164_L316_T0.5200.32
22_F91_D0.5200.32
37_T82_N0.5200.32
217_A228_L0.5200.32
252_W259_H0.5190.32
146_A361_F0.5170.32
71_M226_W0.5160.32
232_L342_F0.5160.32
10_D65_W0.5150.32
92_H346_V0.5150.32
11_L16_I0.5140.32
166_I292_S0.5140.32
127_V144_V0.5130.32
91_D343_V0.5120.32
77_L330_A0.5120.32
260_V283_R0.5120.32
38_L80_K0.5120.32
310_T314_L0.5100.31
43_C311_G0.5100.31
90_K356_A0.5090.31
74_G333_S0.5070.31
342_F346_V0.5070.31
35_I164_L0.5070.31
316_T347_Q0.5060.31
22_F25_S0.5040.31
173_I283_R0.5030.31
214_C218_K0.5020.31
217_A223_P0.5020.31
321_F347_Q0.5010.31
45_A206_L0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zuxA 1 0.7708 98.2 0.905 Contact Map
4n7wA 2 0.7656 97.8 0.915 Contact Map
4bwzA 2 0.9167 97.5 0.92 Contact Map
4czbA 2 0.9375 96.3 0.931 Contact Map
4cz8A 2 0.9245 92.4 0.944 Contact Map
4dveA 3 0.4115 50 0.963 Contact Map
1pw4A 1 0.8438 45.6 0.964 Contact Map
3rlbA 1 0.4089 29.5 0.967 Contact Map
4ezcA 3 0.7917 24.3 0.969 Contact Map
4huqS 1 0.3828 14.3 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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