GREMLIN Database
YHEI - Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI
UniProt: O07550 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 585 (561)
Sequences: 52445 (37187)
Seq/√Len: 1570.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
454_E464_L4.5501.00
365_Q541_L4.4201.00
341_H356_D4.4011.00
338_V360_T4.3431.00
362_R365_Q4.3331.00
426_R430_E4.0261.00
340_S394_S3.9441.00
541_L553_R3.9301.00
556_H566_Y3.8661.00
449_A454_E3.7671.00
429_K441_D3.7121.00
340_S396_T3.4261.00
454_E458_H3.3891.00
336_D360_T3.3711.00
394_S401_P3.3601.00
355_Q549_V3.0971.00
339_F342_V3.0841.00
429_K465_E3.0261.00
429_K433_L2.9871.00
440_T443_E2.9471.00
448_I464_L2.8931.00
563_N567_R2.8931.00
381_I529_L2.8701.00
567_R571_E2.8061.00
352_D355_Q2.7831.00
343_S356_D2.7801.00
441_D445_Q2.7501.00
381_I497_I2.7361.00
413_W494_E2.6321.00
552_E562_N2.5001.00
338_V396_T2.4981.00
432_I448_I2.4961.00
446_Q450_E2.4901.00
336_D362_R2.4241.00
361_V367_V2.3901.00
492_N524_K2.3711.00
386_R389_P2.3711.00
445_Q454_E2.3681.00
415_G493_P2.3581.00
345_T352_D2.3321.00
543_L553_R2.3181.00
45_D276_G2.3111.00
552_E564_G2.3041.00
555_T558_E2.3031.00
436_K443_E2.2901.00
429_K444_V2.2881.00
406_P409_R2.2881.00
343_S352_D2.2071.00
462_S466_T2.2041.00
359_F543_L2.2031.00
366_T539_A2.1761.00
343_S392_E2.1541.00
445_Q449_A2.1421.00
336_D363_K2.1371.00
45_D274_T2.1191.00
432_I444_V2.1161.00
453_F456_D2.0861.00
552_E563_N2.0861.00
339_F359_F2.0651.00
335_G398_S2.0401.00
152_T156_L2.0351.00
11_F96_K2.0271.00
546_D565_W2.0151.00
518_R538_H1.9881.00
389_P403_Q1.9591.00
361_V527_F1.9531.00
510_E532_R1.9521.00
443_E492_N1.9491.00
341_H358_S1.9161.00
345_T391_G1.9081.00
313_N317_S1.9041.00
15_Y92_I1.9011.00
445_Q458_H1.8701.00
554_G558_E1.8501.00
100_H320_T1.8261.00
13_K16_W1.8251.00
447_A451_A1.8181.00
367_V541_L1.8101.00
193_A230_D1.8061.00
158_S267_L1.8011.00
433_L444_V1.8011.00
446_Q449_A1.7591.00
511_A515_K1.7271.00
58_L62_G1.7211.00
433_L441_D1.7071.00
380_I545_M1.7051.00
367_V543_L1.7031.00
505_V513_I1.6821.00
334_P398_S1.6821.00
543_L550_I1.6811.00
368_G539_A1.6761.00
337_I527_F1.6531.00
551_A565_W1.6521.00
452_H512_A1.6381.00
216_Q219_N1.6251.00
450_E519_E1.6211.00
324_D406_P1.6191.00
401_P404_Q1.6091.00
62_G66_V1.6041.00
365_Q540_D1.6041.00
469_G474_A1.6011.00
366_T528_I1.5931.00
546_D551_A1.5921.00
441_D465_E1.5851.00
432_I490_M1.5841.00
448_I457_L1.5781.00
124_D311_R1.5761.00
468_V475_L1.5511.00
336_D398_S1.5461.00
560_L570_Y1.5421.00
552_E567_R1.5391.00
328_P331_L1.5311.00
188_T310_D1.5291.00
443_E446_Q1.5271.00
369_I543_L1.5251.00
369_I380_I1.5251.00
354_L357_I1.5241.00
455_K458_H1.5211.00
445_Q464_L1.5171.00
439_A490_M1.5161.00
558_E562_N1.4951.00
266_F270_R1.4911.00
537_E557_Q1.4691.00
41_G280_S1.4591.00
530_T535_A1.4561.00
362_R541_L1.4431.00
442_K445_Q1.4421.00
103_T320_T1.4341.00
344_F379_T1.4251.00
100_H104_M1.4191.00
448_I454_E1.4161.00
196_A230_D1.4061.00
385_L416_Y1.4001.00
59_F63_I1.3991.00
383_Q395_I1.3971.00
262_G266_F1.3881.00
356_D549_V1.3841.00
462_S467_M1.3811.00
37_P284_Y1.3701.00
565_W568_E1.3611.00
372_K546_D1.3531.00
200_R227_M1.3491.00
443_E490_M1.3471.00
515_K519_E1.3421.00
342_V390_P1.3391.00
339_F384_L1.3321.00
519_E522_K1.3271.00
220_D434_Y1.3251.00
344_F383_Q1.3191.00
557_Q561_A1.3171.00
456_D479_Q1.3141.00
425_S467_M1.3111.00
344_F388_Y1.3011.00
335_G363_K1.3001.00
415_G488_A1.2901.00
460_L466_T1.2811.00
154_G158_S1.2801.00
189_E234_K1.2771.00
368_G536_V1.2761.00
428_V483_I1.2751.00
441_D444_V1.2731.00
433_L439_A1.2701.00
340_S358_S1.2511.00
100_H316_L1.2441.00
182_K185_E1.2441.00
372_K565_W1.2421.00
25_L74_M1.2401.00
193_A234_K1.2381.00
14_A92_I1.2171.00
193_A196_A1.2161.00
373_T509_T1.2161.00
469_G472_G1.2151.00
174_I178_L1.2091.00
442_K446_Q1.2061.00
153_M157_I1.2031.00
450_E489_L1.2011.00
384_L527_F1.2001.00
343_S355_Q1.1961.00
400_V404_Q1.1931.00
390_P402_I1.1911.00
34_M148_T1.1871.00
453_F457_L1.1851.00
267_L272_E1.1841.00
456_D460_L1.1841.00
367_V527_F1.1831.00
336_D399_G1.1791.00
212_R217_E1.1771.00
542_I556_H1.1751.00
459_M479_Q1.1731.00
436_K439_A1.1711.00
521_R526_T1.1701.00
448_I453_F1.1661.00
363_K494_E1.1611.00
481_Q503_S1.1571.00
447_A489_L1.1541.00
204_S220_D1.1541.00
161_L281_F1.1531.00
222_R226_E1.1531.00
110_E388_Y1.1521.00
325_P404_Q1.1461.00
274_T277_E1.1431.00
359_F380_I1.1411.00
475_L483_I1.1381.00
357_I380_I1.1341.00
407_L411_R1.1331.00
445_Q448_I1.1311.00
218_T222_R1.1301.00
97_L315_T1.1251.00
207_G422_L1.1241.00
95_T99_G1.1231.00
400_V405_I1.1221.00
452_H509_T1.1191.00
440_T490_M1.1131.00
334_P363_K1.1101.00
155_F159_W1.1081.00
229_A233_Q1.1061.00
116_D195_G1.1001.00
452_H516_N1.0931.00
458_H463_G1.0911.00
361_V525_T1.0891.00
563_N571_E1.0891.00
155_F162_T1.0881.00
41_G45_D1.0871.00
324_D407_L1.0861.00
352_D391_G1.0781.00
28_A74_M1.0761.00
451_A486_A1.0751.00
341_H392_E1.0741.00
366_T526_T1.0721.00
339_F395_I1.0671.00
100_H103_T1.0651.00
417_V488_A1.0621.00
112_N116_D1.0611.00
530_T536_V1.0481.00
55_E59_F1.0461.00
455_K459_M1.0441.00
556_H560_L1.0441.00
263_Y267_L1.0421.00
186_R237_K1.0421.00
309_L313_N1.0381.00
383_Q390_P1.0351.00
38_K42_N1.0351.00
196_A227_M1.0351.00
110_E382_K1.0341.00
160_K272_E1.0341.00
99_G103_T1.0331.00
339_F380_I1.0321.00
113_R116_D1.0281.00
337_I384_L1.0241.00
220_D223_R1.0231.00
84_G88_L1.0221.00
500_D531_H1.0161.00
168_P256_S1.0151.00
488_A496_L1.0131.00
452_H515_K1.0081.00
330_D333_E1.0081.00
421_H484_S1.0041.00
544_V565_W0.9991.00
159_W163_F0.9971.00
395_I402_I0.9971.00
25_L77_F0.9971.00
430_E433_L0.9961.00
494_E524_K0.9931.00
226_E230_D0.9911.00
565_W569_Q0.9901.00
365_Q553_R0.9871.00
224_F228_T0.9871.00
346_Y353_N0.9841.00
373_T482_R0.9831.00
397_F410_L0.9831.00
409_R412_G0.9821.00
39_L60_Y0.9821.00
92_I96_K0.9811.00
444_V464_L0.9801.00
528_I539_A0.9801.00
496_L524_K0.9791.00
156_L159_W0.9761.00
477_G482_R0.9741.00
237_K240_F0.9731.00
16_W20_T0.9721.00
18_R84_G0.9701.00
20_T24_V0.9691.00
232_Y236_M0.9691.00
211_I220_D0.9671.00
347_P351_S0.9661.00
457_L464_L0.9641.00
447_A490_M0.9631.00
127_A308_S0.9621.00
22_A82_L0.9591.00
462_S465_E0.9581.00
200_R223_R0.9581.00
368_G530_T0.9581.00
178_L182_K0.9561.00
378_T382_K0.9561.00
338_V399_G0.9561.00
452_H519_E0.9561.00
352_D392_E0.9521.00
265_A269_F0.9521.00
41_G277_E0.9511.00
216_Q220_D0.9491.00
154_G281_F0.9451.00
545_M550_I0.9431.00
342_V383_Q0.9391.00
105_S321_D0.9381.00
345_T353_N0.9371.00
450_E520_N0.9371.00
163_F167_I0.9361.00
446_Q492_N0.9341.00
512_A515_K0.9341.00
429_K464_L0.9321.00
337_I397_F0.9311.00
219_N223_R0.9311.00
397_F495_I0.9271.00
468_V474_A0.9251.00
42_N46_D0.9251.00
264_G278_L0.9231.00
485_I498_L0.9171.00
375_S545_M0.9151.00
182_K241_I0.9151.00
223_R227_M0.9131.00
508_K512_A0.9131.00
338_V358_S0.9101.00
429_K445_Q0.9081.00
189_E193_A0.9071.00
306_N310_D0.9061.00
356_D392_E0.9041.00
158_S162_T0.9031.00
25_L81_Q0.9011.00
17_L21_I0.9001.00
175_A248_T0.9001.00
59_F62_G0.9001.00
385_L497_I0.8991.00
96_K100_H0.8991.00
386_R407_L0.8971.00
458_H464_L0.8951.00
188_T192_N0.8931.00
66_V70_A0.8881.00
444_V490_M0.8881.00
417_V485_I0.8871.00
124_D308_S0.8871.00
439_A443_E0.8871.00
91_K95_T0.8841.00
449_A458_H0.8831.00
566_Y569_Q0.8831.00
368_G542_I0.8821.00
564_G567_R0.8821.00
225_N229_A0.8811.00
366_T521_R0.8811.00
405_I410_L0.8801.00
229_A232_Y0.8791.00
108_F112_N0.8791.00
390_P395_I0.8751.00
432_I483_I0.8731.00
469_G473_V0.8721.00
230_D234_K0.8711.00
409_R413_W0.8681.00
10_W13_K0.8671.00
558_E561_A0.8651.00
120_R314_E0.8631.00
390_P403_Q0.8621.00
394_S403_Q0.8591.00
453_F459_M0.8591.00
532_R535_A0.8561.00
189_E237_K0.8541.00
107_P321_D0.8511.00
268_V273_L0.8511.00
363_K398_S0.8491.00
97_L121_G0.8491.00
15_Y88_L0.8481.00
423_L483_I0.8481.00
186_R234_K0.8481.00
385_L414_I0.8471.00
219_N222_R0.8471.00
496_L521_R0.8461.00
550_I553_R0.8461.00
154_G157_I0.8441.00
366_T518_R0.8441.00
408_D412_G0.8441.00
502_L513_I0.8431.00
209_R382_K0.8411.00
357_I550_I0.8381.00
468_V472_G0.8371.00
164_A263_Y0.8331.00
451_A482_R0.8311.00
493_P524_K0.8311.00
423_L480_K0.8301.00
345_T348_S0.8301.00
190_A235_N0.8301.00
22_A85_G0.8301.00
154_G162_T0.8271.00
322_V389_P0.8261.00
402_I410_L0.8251.00
453_F483_I0.8231.00
32_I74_M0.8221.00
546_D549_V0.8221.00
182_K186_R0.8211.00
32_I70_A0.8181.00
340_S360_T0.8161.00
345_T349_S0.8131.00
223_R226_E0.8111.00
157_I277_E0.8111.00
325_P328_P0.8111.00
222_R225_N0.8101.00
185_E189_E0.8091.00
319_E323_T0.8061.00
568_E571_E0.8061.00
514_I530_T0.8051.00
267_L270_R0.8051.00
210_V214_Y0.8021.00
150_F162_T0.8021.00
104_M318_Y0.8001.00
405_I409_R0.8001.00
117_L315_T0.7981.00
427_T430_E0.7981.00
432_I464_L0.7971.00
424_F431_N0.7961.00
173_A177_S0.7961.00
450_E454_E0.7961.00
221_V225_N0.7961.00
335_G525_T0.7941.00
345_T351_S0.7911.00
396_T399_G0.7911.00
100_H319_E0.7901.00
343_S391_G0.7891.00
337_I495_I0.7881.00
227_M230_D0.7871.00
116_D120_R0.7861.00
461_P466_T0.7851.00
9_G13_K0.7851.00
97_L312_V0.7851.00
158_S273_L0.7821.00
333_E398_S0.7821.00
496_L526_T0.7811.00
39_L67_L0.7811.00
218_T221_V0.7761.00
268_V278_L0.7751.00
348_S351_S0.7701.00
510_E514_I0.7701.00
177_S181_S0.7691.00
9_G12_F0.7641.00
276_G280_S0.7631.00
73_I77_F0.7621.00
32_I67_L0.7621.00
42_N60_Y0.7621.00
236_M240_F0.7621.00
312_V316_L0.7611.00
414_I495_I0.7611.00
456_D459_M0.7601.00
56_G59_F0.7601.00
433_L438_D0.7571.00
234_K237_K0.7551.00
160_K267_L0.7521.00
38_K41_G0.7521.00
61_I65_F0.7501.00
120_R124_D0.7491.00
208_V212_R0.7491.00
433_L437_Q0.7481.00
107_P111_K0.7471.00
420_D480_K0.7471.00
514_I535_A0.7461.00
460_L475_L0.7461.00
332_K398_S0.7461.00
412_G491_A0.7451.00
39_L63_I0.7441.00
127_A304_R0.7431.00
143_T147_M0.7421.00
160_K163_F0.7401.00
556_H570_Y0.7401.00
370_A544_V0.7401.00
433_L436_K0.7401.00
76_Y80_H0.7381.00
207_G210_V0.7381.00
267_L271_N0.7371.00
264_G268_V0.7371.00
42_N45_D0.7361.00
153_M156_L0.7361.00
193_A227_M0.7361.00
131_T305_G0.7321.00
560_L567_R0.7311.00
101_L109_Y0.7301.00
233_Q237_K0.7301.00
197_L231_V0.7291.00
62_G65_F0.7281.00
105_S322_V0.7281.00
329_A332_K0.7281.00
230_D233_Q0.7241.00
330_D409_R0.7241.00
481_Q504_A0.7241.00
31_V35_F0.7231.00
28_A70_A0.7221.00
373_T500_D0.7211.00
477_G504_A0.7191.00
162_T281_F0.7161.00
63_I66_V0.7161.00
355_Q547_G0.7151.00
26_L141_D0.7131.00
44_I279_V0.7131.00
189_E192_N0.7121.00
167_I170_P0.7111.00
251_L255_A0.7111.00
60_Y63_I0.7101.00
131_T302_M0.7091.00
45_D48_K0.7091.00
24_V28_A0.7091.00
390_P394_S0.7091.00
453_F464_L0.7081.00
364_G523_G0.7071.00
502_L510_E0.7061.00
364_G525_T0.7041.00
174_I177_S0.7031.00
46_D56_G0.7001.00
18_R88_L0.7001.00
450_E516_N0.7001.00
513_I516_N0.6991.00
181_S185_E0.6991.00
521_R524_K0.6981.00
310_D314_E0.6971.00
447_A486_A0.6971.00
482_R509_T0.6951.00
436_K492_N0.6951.00
30_N144_M0.6931.00
70_A74_M0.6931.00
346_Y379_T0.6911.00
126_Q129_S0.6891.00
428_V457_L0.6871.00
96_K99_G0.6861.00
557_Q560_L0.6851.00
21_I81_Q0.6851.00
142_S294_A0.6831.00
452_H455_K0.6811.00
396_T401_P0.6811.00
361_V365_Q0.6801.00
104_M320_T0.6791.00
191_Q194_F0.6741.00
46_D49_A0.6741.00
382_K388_Y0.6731.00
334_P525_T0.6721.00
367_V553_R0.6691.00
552_E565_W0.6681.00
305_G308_S0.6671.00
410_L414_I0.6661.00
141_D145_F0.6641.00
445_Q457_L0.6611.00
99_G221_V0.6611.00
516_N519_E0.6601.00
381_I527_F0.6601.00
541_L555_T0.6591.00
436_K491_A0.6581.00
443_E447_A0.6581.00
97_L316_L0.6571.00
119_A198_N0.6571.00
383_Q388_Y0.6571.00
562_N565_W0.6551.00
552_E559_L0.6541.00
425_S469_G0.6521.00
497_I527_F0.6511.00
29_V75_S0.6511.00
124_D128_V0.6481.00
149_I287_M0.6461.00
113_R199_D0.6461.00
96_K316_L0.6451.00
366_T538_H0.6451.00
420_D471_K0.6441.00
18_R81_Q0.6421.00
426_R467_M0.6421.00
329_A400_V0.6421.00
10_W96_K0.6421.00
15_Y18_R0.6411.00
354_L545_M0.6411.00
13_K17_L0.6401.00
369_I527_F0.6401.00
116_D311_R0.6401.00
485_I489_L0.6401.00
93_L125_L0.6401.00
328_P333_E0.6381.00
339_F357_I0.6381.00
34_M37_P0.6371.00
433_L448_I0.6371.00
26_L78_W0.6371.00
344_F353_N0.6371.00
263_Y266_F0.6371.00
153_M158_S0.6351.00
536_V539_A0.6351.00
97_L125_L0.6351.00
186_R189_E0.6341.00
423_L468_V0.6311.00
90_E94_R0.6301.00
90_E129_S0.6301.00
155_F166_I0.6301.00
323_T326_K0.6301.00
476_S479_Q0.6291.00
100_H318_Y0.6291.00
397_F402_I0.6291.00
463_G466_T0.6281.00
69_A73_I0.6261.00
187_F238_V0.6261.00
541_L558_E0.6251.00
510_E535_A0.6251.00
552_E560_L0.6241.00
106_P110_E0.6231.00
448_I451_A0.6231.00
485_I513_I0.6231.00
250_K293_F0.6221.00
552_E568_E0.6201.00
56_G60_Y0.6201.00
149_I288_M0.6191.00
142_S146_M0.6191.00
161_L267_L0.6191.00
427_T465_E0.6191.00
425_S474_A0.6171.00
556_H559_L0.6171.00
124_D191_Q0.6171.00
88_L91_K0.6171.00
446_Q520_N0.6161.00
331_L405_I0.6151.00
563_N568_E0.6141.00
239_A243_S0.6131.00
381_I416_Y0.6131.00
157_I280_S0.6131.00
441_D464_L0.6111.00
335_G494_E0.6111.00
290_W294_A0.6111.00
195_G311_R0.6111.00
255_A259_I0.6101.00
144_M148_T0.6091.00
329_A333_E0.6091.00
83_F134_F0.6081.00
451_A485_I0.6081.00
145_F149_I0.6071.00
139_L143_T0.6071.00
507_A510_E0.6061.00
342_V393_G0.6061.00
349_S352_D0.6061.00
398_S494_E0.6041.00
128_V309_L0.6031.00
482_R505_V0.6021.00
553_R558_E0.6011.00
237_K241_I0.6011.00
373_T530_T0.6011.00
348_S391_G0.6011.00
265_A268_V0.6001.00
357_I545_M0.6001.00
108_F117_L0.5991.00
28_A32_I0.5991.00
54_A58_L0.5991.00
505_V509_T0.5981.00
361_V366_T0.5981.00
146_M150_F0.5971.00
45_D49_A0.5971.00
452_H513_I0.5961.00
441_D448_I0.5951.00
390_P401_P0.5951.00
359_F550_I0.5951.00
444_V448_I0.5941.00
345_T392_E0.5941.00
91_K228_T0.5921.00
451_A489_L0.5921.00
566_Y570_Y0.5911.00
38_K153_M0.5911.00
436_K440_T0.5911.00
495_I525_T0.5901.00
38_K157_I0.5891.00
191_Q307_A0.5891.00
478_G506_D0.5881.00
325_P406_P0.5871.00
210_V213_A0.5861.00
93_L128_V0.5861.00
362_R367_V0.5861.00
35_F67_L0.5841.00
156_L160_K0.5841.00
128_V312_V0.5841.00
342_V358_S0.5841.00
510_E534_S0.5841.00
193_A231_V0.5841.00
562_N567_R0.5841.00
119_A195_G0.5831.00
454_E457_L0.5821.00
328_P406_P0.5811.00
125_L129_S0.5801.00
417_V498_L0.5801.00
415_G491_A0.5801.00
397_F405_I0.5801.00
328_P332_K0.5791.00
308_S311_R0.5781.00
179_Y245_F0.5781.00
189_E230_D0.5761.00
506_D509_T0.5761.00
514_I528_I0.5761.00
273_L277_E0.5751.00
547_G551_A0.5741.00
327_Q404_Q0.5741.00
175_A252_L0.5731.00
322_V386_R0.5731.00
83_F87_N0.5731.00
41_G276_G0.5721.00
86_A133_G0.5721.00
273_L278_L0.5711.00
165_A285_L0.5691.00
352_D356_D0.5691.00
233_Q236_M0.5671.00
147_M152_T0.5671.00
130_L301_V0.5671.00
200_R204_S0.5671.00
119_A194_F0.5671.00
17_L20_T0.5671.00
98_M102_L0.5661.00
436_K490_M0.5651.00
537_E556_H0.5641.00
428_V468_V0.5631.00
170_P174_I0.5631.00
20_T23_I0.5621.00
178_L181_S0.5621.00
449_A455_K0.5621.00
407_L410_L0.5621.00
357_I543_L0.5611.00
55_E58_L0.5611.00
58_L61_I0.5601.00
342_V395_I0.5591.00
152_T155_F0.5591.00
433_L490_M0.5581.00
80_H84_G0.5581.00
542_I555_T0.5561.00
105_S108_F0.5561.00
125_L312_V0.5561.00
515_K518_R0.5561.00
130_L134_F0.5551.00
192_N196_A0.5551.00
544_V552_E0.5551.00
173_A176_I0.5531.00
87_N90_E0.5531.00
512_A516_N0.5521.00
15_Y89_M0.5521.00
160_K263_Y0.5521.00
431_N483_I0.5511.00
115_G199_D0.5491.00
29_V74_M0.5481.00
418_P421_H0.5481.00
119_A123_N0.5471.00
515_K538_H0.5471.00
15_Y85_G0.5471.00
382_K416_Y0.5431.00
14_A96_K0.5431.00
501_S530_T0.5431.00
106_P387_Q0.5421.00
38_K280_S0.5421.00
449_A464_L0.5421.00
111_K347_P0.5411.00
171_V174_I0.5411.00
355_Q358_S0.5381.00
243_S247_P0.5381.00
400_V409_R0.5371.00
489_L520_N0.5371.00
348_S352_D0.5361.00
138_T294_A0.5341.00
65_F69_A0.5341.00
327_Q406_P0.5341.00
63_I67_L0.5331.00
72_Y76_Y0.5331.00
74_M77_F0.5321.00
448_I486_A0.5311.00
254_G258_L0.5311.00
33_E71_V0.5311.00
419_Q477_G0.5301.00
120_R311_R0.5291.00
444_V447_A0.5281.00
362_R525_T0.5281.00
551_A563_N0.5281.00
560_L571_E0.5261.00
379_T388_Y0.5261.00
373_T505_V0.5261.00
495_I527_F0.5261.00
90_E125_L0.5251.00
370_A536_V0.5251.00
328_P400_V0.5251.00
30_N34_M0.5241.00
432_I435_G0.5241.00
417_V501_S0.5241.00
186_R238_V0.5231.00
509_T513_I0.5231.00
149_I284_Y0.5211.00
190_A238_V0.5191.00
77_F81_Q0.5181.00
102_L105_S0.5181.00
155_F158_S0.5181.00
159_W162_T0.5171.00
284_Y291_P0.5171.00
527_F543_L0.5171.00
378_T381_I0.5171.00
264_G267_L0.5161.00
514_I538_H0.5151.00
200_R220_D0.5151.00
134_F138_T0.5151.00
369_I545_M0.5151.00
123_N191_Q0.5151.00
560_L563_N0.5151.00
166_I170_P0.5151.00
148_T152_T0.5151.00
366_T523_G0.5141.00
158_S161_L0.5141.00
530_T534_S0.5131.00
109_Y112_N0.5121.00
361_V543_L0.5121.00
194_F198_N0.5121.00
165_A288_M0.5121.00
427_T467_M0.5121.00
478_G482_R0.5111.00
11_F93_L0.5111.00
428_V453_F0.5111.00
565_W570_Y0.5091.00
564_G569_Q0.5091.00
406_P410_L0.5081.00
321_D411_R0.5081.00
369_I529_L0.5081.00
528_I536_V0.5071.00
502_L505_V0.5071.00
379_T383_Q0.5071.00
544_V551_A0.5061.00
501_S528_I0.5061.00
39_L64_F0.5061.00
386_R402_I0.5061.00
52_F56_G0.5061.00
114_T118_M0.5051.00
338_V394_S0.5051.00
520_N523_G0.5041.00
343_S354_L0.5041.00
30_N33_E0.5041.00
39_L42_N0.5041.00
121_G125_L0.5041.00
269_F272_E0.5041.00
370_A533_L0.5031.00
442_K449_A0.5031.00
207_G424_F0.5031.00
482_R504_A0.5031.00
507_A534_S0.5031.00
349_S353_N0.5031.00
171_V175_A0.5021.00
231_V235_N0.5021.00
80_H83_F0.5021.00
516_N520_N0.5021.00
360_T553_R0.5011.00
498_L501_S0.5011.00
196_A199_D0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ry2A 2 0.959 100 0.093 Contact Map
4a82A 2 0.9761 100 0.12 Contact Map
4q4hB 1 0.9778 100 0.149 Contact Map
3b60A 2 0.9761 100 0.156 Contact Map
3b5xA 2 0.9761 100 0.156 Contact Map
4f4cA 1 0.9607 100 0.159 Contact Map
4q4hA 1 0.9744 100 0.169 Contact Map
4mrsA 2 0.9966 100 0.169 Contact Map
3zdqA 2 0.959 100 0.172 Contact Map
4q9hA 1 0.9795 100 0.178 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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