GREMLIN Database
YHEH - Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH
UniProt: O07549 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 673 (557)
Sequences: 50694 (35547)
Seq/√Len: 1506.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
546_E556_I4.4571.00
431_E452_T4.4061.00
454_Q457_E4.1731.00
457_E633_Q4.1341.00
633_Q645_R4.1151.00
434_D448_H4.1151.00
518_G522_S3.8871.00
521_G533_E3.8471.00
541_R546_E3.8471.00
433_R486_D3.8231.00
648_H658_Y3.5741.00
429_R452_T3.5691.00
433_R488_L3.5471.00
546_E550_K3.4731.00
486_D493_S3.2401.00
447_K641_E3.1081.00
521_G557_N3.0411.00
655_E659_Y3.0211.00
533_E537_K2.9611.00
521_G525_S2.9581.00
444_E447_K2.9551.00
532_T535_E2.8531.00
432_F435_V2.8151.00
659_Y663_E2.7861.00
540_L556_I2.7761.00
436_S448_H2.7211.00
644_E654_L2.6281.00
505_H586_A2.5991.00
473_L621_I2.5821.00
431_E488_L2.5661.00
473_L589_I2.5311.00
538_N542_Q2.5211.00
647_N650_E2.4321.00
429_R454_Q2.4161.00
537_K546_E2.4071.00
438_A444_E2.4031.00
635_L645_R2.4011.00
243_T247_L2.3691.00
498_S501_E2.3341.00
554_K558_E2.3321.00
436_S444_E2.3211.00
584_D616_R2.3121.00
436_S484_K2.2981.00
453_A459_V2.2891.00
521_G536_I2.2771.00
478_R481_D2.2751.00
524_V540_L2.2611.00
528_D535_E2.1871.00
507_G585_P2.1651.00
644_E656_G2.1541.00
644_E655_E2.1351.00
429_R455_K2.1311.00
458_T631_A2.1141.00
108_G111_T2.1071.00
451_F635_L2.0561.00
537_K541_R2.0391.00
610_D630_N2.0141.00
638_D657_Q2.0121.00
545_A548_L1.9741.00
139_F370_G1.9691.00
535_E584_D1.9541.00
453_A619_F1.9471.00
481_D495_Y1.9331.00
524_V536_I1.9281.00
438_A483_Q1.9151.00
646_G650_E1.9081.00
537_K550_K1.8951.00
432_F451_F1.8931.00
284_I321_S1.8901.00
150_V154_C1.8821.00
434_D450_S1.8701.00
602_E624_R1.8411.00
428_G490_D1.7931.00
638_D643_V1.7871.00
407_F411_E1.7771.00
192_H414_N1.7651.00
525_S536_I1.7641.00
533_E557_N1.7611.00
459_V633_Q1.7361.00
459_V635_L1.7341.00
472_I637_L1.7111.00
418_A498_S1.7011.00
538_N541_R1.6991.00
307_H310_E1.6831.00
544_G604_V1.6821.00
525_S533_E1.6741.00
635_L642_I1.6631.00
539_A543_V1.6631.00
542_Q611_V1.6631.00
643_V657_Q1.6591.00
139_F368_S1.6561.00
458_T620_V1.6521.00
603_A607_K1.6441.00
457_E632_D1.6331.00
430_V619_F1.6291.00
249_D361_L1.6171.00
111_T114_D1.6131.00
460_A631_A1.6051.00
154_C158_G1.5641.00
535_E538_N1.5611.00
493_S496_N1.5601.00
427_L490_D1.5531.00
461_L635_L1.5441.00
561_I566_T1.5431.00
560_V567_L1.5391.00
216_D405_R1.5381.00
650_E654_L1.5361.00
429_R490_D1.5351.00
597_I605_I1.5271.00
112_V115_G1.5261.00
644_E659_Y1.5221.00
279_Q404_G1.5181.00
652_M662_Y1.5111.00
151_L155_L1.5011.00
531_M582_A1.5001.00
537_K556_I1.4941.00
547_P550_K1.4941.00
657_Q660_Q1.4881.00
195_K414_N1.4791.00
554_K559_P1.4621.00
360_S364_A1.4601.00
540_L549_L1.4561.00
287_D321_S1.4421.00
534_E537_K1.4351.00
524_V582_A1.4291.00
629_R649_E1.4251.00
291_K318_L1.4251.00
454_Q633_Q1.4201.00
461_L472_I1.4191.00
246_F253_A1.4161.00
446_L449_I1.4071.00
464_H638_D1.3961.00
432_F476_L1.3961.00
649_E653_A1.3951.00
611_V614_Q1.3901.00
280_K325_F1.3771.00
437_F471_S1.3731.00
540_L546_E1.3661.00
517_S559_P1.3631.00
246_F250_V1.3631.00
657_Q661_M1.3611.00
477_F508_I1.3571.00
106_F110_R1.3561.00
475_L487_V1.3531.00
192_H196_M1.3491.00
135_K374_A1.3451.00
435_V482_A1.3381.00
607_K611_V1.3361.00
622_A627_T1.3311.00
658_Y661_M1.3111.00
284_I325_F1.3091.00
284_I287_D1.3081.00
548_L571_E1.2981.00
533_E536_I1.2971.00
426_A490_D1.2911.00
448_H641_E1.2891.00
111_T115_G1.2841.00
507_G580_A1.2821.00
273_Y276_Y1.2791.00
525_S531_M1.2781.00
535_E582_A1.2751.00
460_A628_I1.2741.00
534_E538_N1.2741.00
111_T188_D1.2711.00
428_G455_K1.2661.00
110_R113_S1.2641.00
552_L558_E1.2631.00
437_F480_Y1.2591.00
108_G112_V1.2541.00
419_G496_N1.2541.00
311_T526_L1.2531.00
436_S447_K1.2401.00
492_K496_N1.2401.00
135_K139_F1.2391.00
542_Q581_L1.2331.00
433_R450_S1.2321.00
437_F475_L1.2291.00
613_K618_T1.2231.00
265_L269_I1.2161.00
132_K136_Q1.2041.00
320_E324_Y1.2021.00
464_H657_Q1.1981.00
451_F472_I1.1981.00
429_R491_G1.1971.00
295_S311_T1.1851.00
465_T601_T1.1831.00
655_E663_E1.1781.00
476_L619_F1.1771.00
545_A549_L1.1761.00
187_Q191_S1.1741.00
309_K313_R1.1711.00
192_H410_L1.1691.00
444_E483_Q1.1651.00
427_L455_K1.1621.00
459_V619_F1.1551.00
455_K586_A1.1541.00
361_L366_I1.1511.00
313_R317_E1.1431.00
551_K571_E1.1421.00
368_S371_V1.1411.00
550_K555_G1.1401.00
245_L375_F1.1351.00
287_D318_L1.1331.00
449_I472_I1.1331.00
354_W360_S1.1271.00
540_L545_A1.1221.00
528_D531_M1.1221.00
520_I575_I1.1201.00
131_E378_Y1.1201.00
482_A494_I1.1191.00
634_I648_H1.1171.00
191_S195_K1.1141.00
548_L552_L1.1121.00
277_Y328_R1.1091.00
119_I166_F1.1081.00
561_I564_G1.1061.00
252_L375_F1.1031.00
499_R503_R1.1031.00
573_Q595_A1.0971.00
202_D480_Y1.0961.00
492_K497_M1.0911.00
418_A499_R1.0851.00
537_K540_L1.0841.00
501_E504_S1.0831.00
539_A581_L1.0791.00
189_V409_L1.0781.00
298_G514_Y1.0771.00
192_H195_K1.0721.00
204_L208_K1.0701.00
303_Q308_Q1.0641.00
184_K188_D1.0641.00
458_T618_T1.0611.00
107_D111_T1.0601.00
432_F472_I1.0591.00
124_K128_Y1.0581.00
544_G607_K1.0561.00
544_G601_T1.0551.00
648_H652_M1.0521.00
509_V580_A1.0441.00
532_T582_A1.0431.00
620_V631_A1.0431.00
567_L575_I1.0391.00
107_D411_E1.0361.00
317_E321_S1.0361.00
208_K286_S1.0351.00
432_F487_V1.0341.00
176_M180_R1.0341.00
434_D484_K1.0331.00
205_P208_K1.0321.00
547_P551_K1.0311.00
269_I273_Y1.0261.00
430_V476_L1.0251.00
128_Y240_G1.0221.00
656_G659_Y1.0211.00
323_F327_N1.0201.00
403_A407_F1.0201.00
489_I502_L1.0151.00
311_T314_E1.0141.00
136_Q140_Q1.0131.00
120_T124_K1.0121.00
543_V578_A1.0111.00
202_D474_N1.0111.00
315_F319_N1.0091.00
453_A617_T1.0081.00
107_D110_R1.0061.00
604_V607_K1.0061.00
291_K314_E1.0061.00
622_A628_I1.0051.00
328_R331_N1.0041.00
444_E484_K1.0031.00
586_A616_R1.0031.00
544_G611_V0.9981.00
219_A402_S0.9971.00
636_V657_Q0.9931.00
538_N584_D0.9911.00
475_L482_A0.9831.00
544_G608_A0.9831.00
251_K366_I0.9821.00
439_Y445_V0.9771.00
513_P576_S0.9771.00
259_I348_A0.9681.00
549_L556_I0.9671.00
239_F243_T0.9641.00
307_H311_T0.9601.00
280_K284_I0.9601.00
310_E314_E0.9561.00
316_E320_E0.9561.00
314_E318_L0.9511.00
279_Q283_S0.9491.00
254_F258_A0.9471.00
539_A582_A0.9451.00
106_F111_T0.9441.00
522_S525_S0.9441.00
600_E604_V0.9421.00
433_R452_T0.9411.00
457_E645_R0.9391.00
521_G537_K0.9391.00
133_L152_L0.9351.00
431_E491_G0.9331.00
321_S325_F0.9331.00
119_I169_G0.9331.00
536_I556_I0.9331.00
650_E653_A0.9291.00
542_Q612_V0.9271.00
250_V254_F0.9261.00
197_P415_T0.9251.00
467_S637_L0.9241.00
580_A588_L0.9231.00
200_Y204_L0.9231.00
122_G166_F0.9231.00
302_I311_T0.9211.00
478_R499_R0.9191.00
135_K371_V0.9181.00
151_L154_C0.9171.00
108_G114_D0.9161.00
588_L616_R0.9091.00
501_E505_H0.9061.00
400_R404_G0.9061.00
465_T574_L0.9061.00
183_Q187_Q0.9051.00
435_V475_L0.9031.00
448_H484_K0.9021.00
320_E323_F0.9011.00
560_V566_T0.8991.00
554_K557_N0.8971.00
541_R550_K0.8971.00
438_A445_V0.8961.00
487_V494_I0.8951.00
497_M502_L0.8951.00
248_L371_V0.8931.00
637_L642_I0.8921.00
147_K151_L0.8901.00
592_E623_H0.8861.00
280_K328_R0.8861.00
273_Y332_L0.8831.00
460_A622_A0.8811.00
281_I326_Q0.8801.00
199_R415_T0.8801.00
500_Q504_S0.8791.00
482_A495_Y0.8781.00
264_W268_V0.8781.00
460_A634_I0.8771.00
158_G162_F0.8761.00
486_D495_Y0.8751.00
431_E450_S0.8741.00
189_V213_I0.8741.00
108_G115_G0.8721.00
318_L321_S0.8721.00
458_T610_D0.8721.00
212_R408_E0.8711.00
310_E313_R0.8711.00
531_M535_E0.8691.00
116_K174_L0.8681.00
199_R203_N0.8681.00
536_I582_A0.8661.00
642_I645_R0.8581.00
216_D402_S0.8581.00
477_F506_M0.8581.00
440_Q443_E0.8571.00
489_I587_I0.8551.00
106_F109_N0.8551.00
115_G184_K0.8551.00
561_I565_S0.8541.00
477_F589_I0.8531.00
509_V577_F0.8521.00
312_M316_E0.8511.00
545_A551_K0.8501.00
638_D641_E0.8491.00
521_G556_I0.8471.00
359_A363_A0.8471.00
660_Q663_E0.8451.00
277_Y325_F0.8441.00
455_K490_D0.8431.00
355_H361_L0.8421.00
425_R490_D0.8421.00
276_Y280_K0.8391.00
413_K417_E0.8381.00
438_A442_G0.8361.00
458_T613_K0.8361.00
416_E481_D0.8361.00
309_K312_M0.8351.00
550_K556_I0.8351.00
423_K497_M0.8351.00
245_L253_A0.8331.00
482_A487_V0.8311.00
119_I173_L0.8251.00
188_D192_H0.8251.00
140_Q143_Q0.8241.00
148_G151_L0.8231.00
658_Y662_Y0.8231.00
361_L364_A0.8201.00
142_Y145_E0.8191.00
132_K135_K0.8191.00
313_R316_E0.8181.00
268_V272_R0.8181.00
421_P492_K0.8181.00
423_K426_A0.8171.00
300_T474_N0.8171.00
548_L551_K0.8161.00
655_E660_Q0.8151.00
542_Q546_E0.8151.00
314_E317_E0.8131.00
266_W340_L0.8111.00
624_R627_T0.8101.00
656_G661_M0.8071.00
515_L575_I0.8061.00
244_A248_L0.8061.00
109_N112_V0.8051.00
244_A247_L0.8021.00
362_N367_V0.8001.00
588_L613_K0.8001.00
470_S474_N0.7991.00
242_F253_A0.7981.00
247_L250_V0.7971.00
594_T605_I0.7961.00
325_F328_R0.7961.00
358_G362_N0.7961.00
370_G374_A0.7951.00
421_P496_N0.7941.00
488_L491_G0.7921.00
327_N331_N0.7911.00
134_T138_L0.7901.00
655_E658_Y0.7901.00
438_A441_E0.7901.00
585_P616_R0.7891.00
430_V489_I0.7891.00
301_I305_F0.7881.00
273_Y277_Y0.7881.00
449_I642_I0.7871.00
136_Q139_F0.7871.00
436_S483_Q0.7871.00
524_V575_I0.7871.00
552_L567_L0.7861.00
545_A575_I0.7841.00
525_S530_R0.7791.00
406_V410_L0.7771.00
602_E606_Q0.7771.00
288_I322_H0.7761.00
139_F142_Y0.7751.00
515_L572_R0.7751.00
504_S583_F0.7701.00
428_G617_T0.7661.00
362_N372_L0.7641.00
494_I502_L0.7621.00
425_R586_A0.7611.00
255_V355_H0.7611.00
569_S574_L0.7601.00
128_Y131_E0.7601.00
506_M587_I0.7581.00
208_K212_R0.7571.00
107_D112_V0.7571.00
423_K501_E0.7551.00
519_T522_S0.7551.00
223_L399_A0.7541.00
246_F257_L0.7531.00
127_A131_E0.7501.00
248_L374_A0.7481.00
524_V556_I0.7471.00
321_S324_Y0.7441.00
193_I201_F0.7441.00
577_F590_L0.7431.00
209_V409_L0.7421.00
497_M501_E0.7421.00
512_D572_R0.7411.00
544_G547_P0.7401.00
234_S388_G0.7391.00
196_M412_E0.7391.00
219_A398_L0.7381.00
189_V406_V0.7381.00
251_K254_F0.7381.00
152_L155_L0.7371.00
543_V574_L0.7361.00
299_M303_Q0.7361.00
422_A501_E0.7361.00
361_L365_G0.7341.00
126_R162_F0.7341.00
165_F169_G0.7321.00
136_Q152_L0.7321.00
251_K361_L0.7311.00
241_I381_R0.7301.00
192_H413_K0.7281.00
525_S529_E0.7281.00
124_K127_A0.7271.00
280_K283_S0.7271.00
359_A362_N0.7271.00
284_I318_L0.7261.00
125_S129_A0.7241.00
462_V636_V0.7231.00
438_A443_E0.7231.00
116_K177_S0.7231.00
188_D191_S0.7231.00
126_R166_F0.7221.00
588_L618_T0.7221.00
447_K639_K0.7221.00
528_D584_D0.7211.00
458_T630_N0.7191.00
258_A261_P0.7191.00
340_L344_I0.7171.00
657_Q662_Y0.7171.00
443_E447_K0.7171.00
253_A375_F0.7161.00
112_V184_K0.7141.00
324_Y328_R0.7141.00
154_C157_G0.7121.00
654_L657_Q0.7111.00
272_R276_Y0.7101.00
235_G239_F0.7101.00
298_G301_I0.7091.00
482_A486_D0.7091.00
107_D114_D0.7091.00
132_K244_A0.7091.00
153_I157_G0.7081.00
520_I549_L0.7081.00
140_Q148_G0.7061.00
430_V587_I0.7051.00
422_A498_S0.7041.00
404_G408_E0.7031.00
168_Y172_Y0.7011.00
133_L159_L0.7001.00
249_D253_A0.6991.00
502_L506_M0.6981.00
139_F143_Q0.6981.00
182_I221_R0.6981.00
465_T592_E0.6971.00
517_S561_I0.6971.00
205_P290_A0.6941.00
343_V347_L0.6921.00
133_L136_Q0.6911.00
191_S312_M0.6911.00
141_F145_E0.6911.00
155_L158_G0.6901.00
240_G243_T0.6901.00
560_V564_G0.6901.00
188_D410_L0.6891.00
346_N350_V0.6871.00
488_L493_S0.6871.00
574_L601_T0.6861.00
542_Q608_A0.6841.00
633_Q647_N0.6841.00
660_Q664_L0.6821.00
459_V645_R0.6801.00
528_D583_F0.6801.00
243_T246_F0.6791.00
249_D367_V0.6781.00
456_G615_G0.6771.00
223_L396_L0.6731.00
162_F166_F0.6731.00
633_Q650_E0.6721.00
439_Y471_S0.6721.00
516_F523_N0.6721.00
652_M659_Y0.6711.00
265_L268_V0.6701.00
148_G152_L0.6691.00
545_A556_I0.6681.00
277_Y280_K0.6671.00
538_N612_V0.6671.00
120_T233_T0.6641.00
482_A493_S0.6631.00
525_S528_D0.6631.00
417_E420_E0.6621.00
569_S596_H0.6601.00
197_P416_E0.6591.00
473_L619_F0.6571.00
644_E651_L0.6551.00
474_N480_Y0.6551.00
116_K120_T0.6541.00
416_E478_R0.6541.00
108_G188_D0.6531.00
241_I382_L0.6531.00
126_R159_L0.6531.00
441_E483_Q0.6501.00
553_P558_E0.6501.00
426_A505_H0.6491.00
130_A134_T0.6481.00
363_A366_I0.6481.00
384_Q388_G0.6431.00
446_L637_L0.6411.00
115_G180_R0.6401.00
189_V410_L0.6391.00
649_E652_M0.6391.00
489_I494_I0.6391.00
110_R114_D0.6371.00
249_D252_L0.6371.00
539_A578_A0.6371.00
535_E539_A0.6361.00
150_V153_I0.6351.00
135_K138_L0.6351.00
286_S405_R0.6351.00
605_I608_A0.6331.00
421_P424_E0.6321.00
133_L155_L0.6321.00
185_M217_T0.6321.00
256_C379_L0.6291.00
644_E657_Q0.6281.00
518_G559_P0.6271.00
198_I202_D0.6251.00
212_R216_D0.6251.00
606_Q630_N0.6241.00
180_R183_Q0.6241.00
196_M414_N0.6241.00
118_T122_G0.6231.00
435_V485_G0.6231.00
106_F113_S0.6221.00
330_L334_S0.6221.00
456_G617_T0.6211.00
475_L480_Y0.6211.00
189_V217_T0.6211.00
602_E627_T0.6191.00
594_T602_E0.6181.00
109_N113_S0.6171.00
282_R285_N0.6171.00
533_E556_I0.6141.00
141_F144_P0.6131.00
461_L619_F0.6131.00
211_A289_N0.6121.00
490_D586_A0.6111.00
645_R650_E0.6111.00
182_I186_R0.6111.00
138_L373_Y0.6101.00
597_I601_T0.6101.00
443_E639_K0.6091.00
216_D282_R0.6091.00
172_Y176_M0.6081.00
269_I272_R0.6081.00
577_F581_L0.6081.00
328_R332_L0.6081.00
427_L617_T0.6071.00
606_Q627_T0.6051.00
220_I403_A0.6041.00
324_Y327_N0.6041.00
573_Q596_H0.6031.00
648_H662_Y0.6031.00
540_L543_V0.6021.00
644_E660_Q0.6021.00
644_E652_M0.6021.00
399_A402_S0.6011.00
599_T602_E0.6001.00
197_P200_Y0.6001.00
419_G498_S0.6001.00
241_I378_Y0.6001.00
451_F642_I0.5991.00
519_T557_N0.5991.00
577_F605_I0.5981.00
161_V165_F0.5971.00
132_K248_L0.5971.00
345_R349_F0.5971.00
607_K610_D0.5971.00
203_N440_Q0.5971.00
367_V371_V0.5971.00
453_A457_E0.5971.00
106_F112_V0.5971.00
543_V577_F0.5961.00
123_D127_A0.5951.00
124_K131_E0.5941.00
517_S566_T0.5931.00
192_H412_E0.5931.00
107_D113_S0.5931.00
251_K355_H0.5931.00
608_A611_V0.5921.00
183_Q319_N0.5911.00
282_R401_V0.5911.00
284_I322_H0.5901.00
544_G605_I0.5901.00
358_G361_L0.5891.00
222_D226_T0.5891.00
628_I631_A0.5891.00
131_E135_K0.5871.00
589_I619_F0.5871.00
270_Y336_M0.5871.00
238_M242_F0.5871.00
648_H651_L0.5861.00
128_Y132_K0.5851.00
107_D407_F0.5831.00
231_F235_G0.5831.00
261_P265_L0.5821.00
175_Q226_T0.5821.00
512_D563_K0.5811.00
643_V655_E0.5811.00
587_I617_T0.5811.00
111_T184_K0.5801.00
291_K311_T0.5801.00
120_T128_Y0.5781.00
222_D395_K0.5781.00
277_Y329_M0.5771.00
283_S287_D0.5771.00
280_K321_S0.5751.00
659_Y662_Y0.5751.00
278_N329_M0.5741.00
473_L508_I0.5741.00
435_V450_S0.5741.00
449_I637_L0.5741.00
543_V581_L0.5731.00
546_E549_L0.5731.00
417_E498_S0.5731.00
301_I304_A0.5731.00
449_I635_L0.5721.00
606_Q622_A0.5711.00
536_I540_L0.5711.00
525_S540_L0.5691.00
499_R502_L0.5681.00
175_Q179_N0.5681.00
507_G583_F0.5681.00
178_A225_V0.5681.00
528_D582_A0.5671.00
541_R547_P0.5671.00
636_V644_E0.5671.00
438_A484_K0.5661.00
211_A285_N0.5651.00
435_V487_V0.5631.00
634_I647_N0.5621.00
537_K549_L0.5611.00
442_G445_V0.5601.00
230_T388_G0.5601.00
652_M663_E0.5601.00
452_T645_R0.5591.00
568_S571_E0.5591.00
613_K616_R0.5591.00
200_Y209_V0.5591.00
264_W267_S0.5571.00
123_D167_Q0.5571.00
602_E626_S0.5571.00
629_R648_H0.5571.00
515_L560_V0.5571.00
655_E661_M0.5561.00
349_F352_L0.5561.00
107_D115_G0.5561.00
654_L659_Y0.5541.00
347_L351_C0.5541.00
342_N387_T0.5541.00
122_G126_R0.5541.00
570_G598_D0.5521.00
164_V168_Y0.5521.00
291_K295_S0.5511.00
533_E540_L0.5511.00
262_I265_L0.5511.00
105_S108_G0.5501.00
155_L159_L0.5501.00
124_K236_I0.5491.00
510_L513_P0.5491.00
574_L597_I0.5481.00
190_F194_Q0.5471.00
120_T170_Q0.5461.00
185_M220_I0.5461.00
639_K643_V0.5451.00
489_I497_M0.5441.00
437_F445_V0.5431.00
453_A458_T0.5431.00
350_V354_W0.5431.00
367_V372_L0.5421.00
128_Y135_K0.5421.00
351_C355_H0.5421.00
322_H326_Q0.5411.00
462_V628_I0.5401.00
247_L251_K0.5401.00
461_L637_L0.5391.00
454_Q459_V0.5391.00
281_I329_M0.5391.00
594_T597_I0.5381.00
206_A210_V0.5361.00
198_I479_F0.5361.00
465_T622_A0.5361.00
474_N508_I0.5361.00
233_T237_Y0.5361.00
211_A286_S0.5351.00
465_T597_I0.5341.00
348_A351_C0.5341.00
520_I560_V0.5341.00
126_R130_A0.5341.00
145_E148_G0.5321.00
555_G558_E0.5311.00
250_V253_A0.5301.00
619_F635_L0.5291.00
541_R556_I0.5281.00
432_F449_I0.5271.00
509_V590_L0.5261.00
234_S238_M0.5261.00
470_S473_L0.5261.00
182_I217_T0.5251.00
402_S405_R0.5241.00
217_T406_V0.5241.00
169_G173_L0.5231.00
581_L612_V0.5221.00
138_L141_F0.5221.00
447_K450_S0.5211.00
179_N182_I0.5201.00
581_L608_A0.5201.00
428_G586_A0.5201.00
498_S502_L0.5191.00
523_N575_I0.5191.00
426_A455_K0.5191.00
207_G290_A0.5181.00
645_R654_L0.5181.00
129_A132_K0.5181.00
122_G162_F0.5161.00
117_L120_T0.5161.00
171_H175_Q0.5141.00
344_I348_A0.5141.00
453_A635_L0.5141.00
525_S582_A0.5141.00
355_H360_S0.5141.00
419_G501_E0.5121.00
524_V527_D0.5121.00
285_N289_N0.5111.00
197_P412_E0.5111.00
132_K378_Y0.5101.00
180_R184_K0.5101.00
511_Q569_S0.5101.00
128_Y136_Q0.5091.00
132_K374_A0.5091.00
601_T604_V0.5091.00
277_Y332_L0.5081.00
656_G660_Q0.5081.00
339_N342_N0.5081.00
375_F379_L0.5081.00
287_D290_A0.5071.00
444_E448_H0.5061.00
452_T455_K0.5061.00
256_C382_L0.5051.00
208_K405_R0.5051.00
358_G372_L0.5051.00
317_E320_E0.5041.00
436_S446_L0.5041.00
213_I217_T0.5031.00
620_V628_I0.5031.00
461_L621_I0.5031.00
360_S363_A0.5031.00
540_L578_A0.5031.00
129_A159_L0.5031.00
179_N183_Q0.5021.00
587_I619_F0.5021.00
593_A622_A0.5021.00
218_E221_R0.5021.00
421_P425_R0.5011.00
346_N349_F0.5011.00
342_N349_F0.5011.00
201_F204_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ry2A 2 0.9599 100 0.169 Contact Map
4a82A 2 0.838 100 0.19 Contact Map
4f4cA 1 0.9272 100 0.223 Contact Map
4q4hB 1 0.8588 100 0.223 Contact Map
4q9hA 1 0.8425 100 0.231 Contact Map
3b60A 2 0.841 100 0.234 Contact Map
3b5xA 2 0.841 100 0.235 Contact Map
3wmgA 1 0.8425 100 0.242 Contact Map
3zdqA 2 0.8232 100 0.243 Contact Map
4mrsA 2 0.8588 100 0.243 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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