YVFR - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YVFR - Uncharacterized ABC transporter ATP-binding protein YvfR

UniProt:	O07016	Sequences: MMKEAVTVSNVTKHFQRKTAVNNISFSIEKGEIAAILGPNGAGKTTVVSMILGLLKPSEGEIKLFNRVPDDQQVREKIGVMLQEVSVMPGLKVDEILELFRSYYPNPLSMKELVSLTALTKEDLKTRAEKLSGGQKRRLSFALALAGNPELLILDEPTVGMDTSSRHRFWQTIHGLSDQGKTIIFSTHYLQEADDAAQRILFFTEGQLVADGSPMQIRSRIQKQSVSFTLHSSESLERLSCHPEVERVIHEHERTIIQTSNTDKVLALIFQENIHARDIRIEQATLDEAFRQLADGNREAM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	301 (234)
Sequences:	86453 (51505)
Seq/√Len:	3367.0

ECOLI - YADG PROV FBPC METN POTG MALK CYSA UGPC POTA YCJV YDCT DDPD SAPD YEHX DPPD DPPF MODC OPPD OPPF MACB ARAG RBSA YHES UUP GSIA DDPF FEPC MLAF SAPF HISP FECE TAUB SSUB FHUC ZNUC YECC LSRA YTFR PHNC PHNK MDLA MDLB NIKE GLNQ CYDC YHDZ LIVG LPTB LIVF MSBA YOJI GLTL ALSA YPHE ETTA CYDD XYLG BTUD LOLD SUFC ARTP MODF MGLA PSTB THIQ FTSE FETA NIKD YBBA CCMA YDDA PHNL YBHF YEJF YNJD YBIT YHIH
BACSU - YVFR YDBJ OPUBA YFIL YHCH OPUCA YCBN YXLF YVRA YHAQ OPUAA YURJ METN MSMX TAGH YKFD YTRB OPPD DPPD APPD OPPF APPF YUSV YFMM YFMR RBSA YDIF ECFA1 FHUC YKPA YFMF SUFC TCYN SUNT SKFE YCLP YHEH YLMA ECSA YFIC ECFA2 YFIB YXDL YXEO BMRA YKNV YGAD BCEA YWJA YKOD YKNU YHEI YTLC ALBC TCYC GLNQ NATA ARTM YVCR CYDD YJKB SSUB FTSE YTHP CYDC PSTB1 MNTB PSTB2 YVRO YUFO YYBJ EXPZ YHCG YKNY ZNUC YCLH YYDI YTRE
HALSA - Q9HRJ6 Q9HMU8 Q9HMX3 BTUDA Q9HHQ5 Q9HMW0 Q9HNZ9 Q9HR06 Q9HRH8 Q9HMT3 Q9HMX2 Q9HMG1 PHNC Q9HHM2 PSTB2 Q9HSQ7 Q9HNY3 Q9HMG6 Q9HRZ9 Y1631 Q9HRV7 Y2317 Q9HS04 Q9HHR7 PSTB1 Q9HR96 Q9HQA8 Q9HT03 Q9HR21 Q9HMC1 Q9HMW1
SULSO - Q7LX64 Q97YK2 Q97UF2 Q97X18 Q97YY4 Q97UY8 Q97VH6 Q97UH3 Q97ZC0 Q97YQ7 Q97VC1 Q97VF5 Q97VK8 Q97YP7 Q97VK9 Q97UD4 Q97YP3 Q97VF4 Q97YP8 Q97UJ9 Q97Z03 Q97U54 Q7LY07 Q980W0 Q97UH4 Q97W42 Y2030 Q97VM2 Y1893 Q97V00 PSTB Q97V01 Q7LX80 Q7LXM4 Q97VY4 Q97Z56 Q97UC2 Q97Z96 Q97YP4 Q97UG5 Q97ZU0 Q980K5 Q980E6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
32_E	199_R	3.575	1.00
77_K	150_E	3.054	1.00
19_T	22_N	3.047	1.00
7_T	27_S	3.021	1.00
34_A	201_L	3.001	1.00
10_N	23_N	2.891	1.00
9_S	61_E	2.819	1.00
123_D	126_T	2.736	1.00
199_R	211_D	2.708	1.00
35_A	197_A	2.699	1.00
14_H	19_T	2.650	1.00
61_E	68_V	2.597	1.00
29_E	32_E	2.496	1.00
7_T	63_K	2.486	1.00
213_S	216_Q	2.364	1.00
13_K	50_M	2.324	1.00
12_T	59_E	2.321	1.00
212_G	216_Q	2.311	1.00
22_N	207_Q	2.231	1.00
12_T	19_T	2.224	1.00
65_F	150_E	2.131	1.00
201_L	208_L	2.117	1.00
9_S	63_K	2.107	1.00
12_T	23_N	2.095	1.00
201_L	211_D	2.036	1.00
8_V	11_V	1.957	1.00
115_S	120_T	1.893	1.00
30_K	150_E	1.856	1.00
112_E	116_L	1.852	1.00
111_K	124_L	1.845	1.00
175_G	179_Q	1.777	1.00
93_V	131_L	1.761	1.00
94_D	124_L	1.760	1.00
48_V	186_S	1.736	1.00
15_F	20_A	1.662	1.00
148_N	181_K	1.662	1.00
15_F	46_T	1.662	1.00
94_D	98_E	1.645	1.00
126_T	130_K	1.643	1.00
109_S	148_N	1.633	1.00
194_D	215_M	1.627	1.00
174_H	195_D	1.624	1.00
48_V	153_I	1.600	1.00
187_T	193_A	1.531	1.00
116_L	175_G	1.517	1.00
94_D	125_K	1.514	1.00
68_V	71_D	1.503	1.00
13_K	55_L	1.500	1.00
116_L	179_Q	1.490	1.00
212_G	217_I	1.475	1.00
13_K	58_S	1.458	1.00
65_F	77_K	1.453	1.00
26_F	201_L	1.448	1.00
10_N	25_S	1.442	1.00
98_E	110_M	1.431	1.00
8_V	26_F	1.428	1.00
97_L	114_V	1.410	1.00
98_E	106_N	1.396	1.00
12_T	22_N	1.386	1.00
113_L	146_A	1.369	1.00
176_L	181_K	1.359	1.00
32_E	198_Q	1.358	1.00
11_V	57_P	1.353	1.00
34_A	211_D	1.345	1.00
113_L	117_T	1.343	1.00
14_H	58_S	1.341	1.00
114_V	124_L	1.336	1.00
5_A	65_F	1.334	1.00
109_S	112_E	1.318	1.00
28_I	34_A	1.302	1.00
63_K	68_V	1.273	1.00
216_Q	220_R	1.270	1.00
35_A	193_A	1.262	1.00
29_E	199_R	1.257	1.00
92_K	95_E	1.239	1.00
24_I	47_V	1.234	1.00
107_P	111_K	1.230	1.00
26_F	47_V	1.225	1.00
111_K	115_S	1.221	1.00
33_I	177_S	1.218	1.00
94_D	110_M	1.213	1.00
154_L	183_I	1.202	1.00
204_T	209_V	1.195	1.00
91_L	95_E	1.177	1.00
53_G	56_K	1.175	1.00
8_V	51_I	1.174	1.00
34_A	199_R	1.171	1.00
94_D	107_P	1.162	1.00
223_K	226_V	1.161	1.00
5_A	27_S	1.152	1.00
52_L	80_V	1.145	1.00
221_I	225_S	1.145	1.00
94_D	111_K	1.130	1.00
224_Q	227_S	1.125	1.00
9_S	27_S	1.122	1.00
50_M	57_P	1.118	1.00
5_A	30_K	1.104	1.00
113_L	142_A	1.099	1.00
96_I	143_L	1.090	1.00
170_W	192_E	1.087	1.00
118_A	168_R	1.079	1.00
21_V	50_M	1.078	1.00
36_I	47_V	1.076	1.00
30_K	65_F	1.076	1.00
177_S	183_I	1.071	1.00
33_I	197_A	1.047	1.00
210_A	220_R	1.046	1.00
92_K	125_K	1.045	1.00
167_H	171_Q	1.035	1.00
123_D	131_L	1.018	1.00
36_I	184_I	1.018	1.00
49_S	55_L	1.016	1.00
108_L	112_E	1.013	1.00
225_S	229_T	1.010	1.00
9_S	25_S	1.009	1.00
83_Q	133_G	1.007	1.00
215_M	219_S	1.000	1.00
33_I	183_I	0.999	1.00
174_H	177_S	0.995	1.00
104_Y	147_G	0.982	1.00
102_S	106_N	0.974	1.00
79_G	149_P	0.971	1.00
98_E	107_P	0.968	1.00
5_A	29_E	0.968	1.00
172_T	175_G	0.959	1.00
90_G	95_E	0.959	1.00
209_V	223_K	0.953	1.00
161_M	169_F	0.945	1.00
216_Q	219_S	0.944	1.00
101_R	146_A	0.943	1.00
114_V	119_L	0.942	1.00
152_L	181_K	0.940	1.00
8_V	47_V	0.939	1.00
166_R	192_E	0.936	1.00
81_M	154_L	0.930	1.00
97_L	146_A	0.929	1.00
224_Q	228_F	0.926	1.00
131_L	139_L	0.923	1.00
200_I	214_P	0.920	1.00
47_V	203_F	0.916	1.00
128_A	139_L	0.916	1.00
98_E	102_S	0.911	1.00
166_R	189_Y	0.910	1.00
10_N	59_E	0.903	1.00
92_K	127_R	0.901	1.00
73_Q	76_E	0.896	1.00
39_P	204_T	0.885	1.00
8_V	62_I	0.883	1.00
95_E	98_E	0.881	1.00
112_E	115_S	0.880	1.00
117_T	142_A	0.875	1.00
36_I	201_L	0.873	1.00
67_R	77_K	0.866	1.00
173_I	183_I	0.865	1.00
52_L	153_I	0.861	1.00
81_M	141_F	0.858	1.00
152_L	183_I	0.855	1.00
154_L	173_I	0.854	1.00
33_I	185_F	0.851	1.00
177_S	198_Q	0.850	1.00
79_G	144_A	0.845	1.00
93_V	139_L	0.844	1.00
51_I	184_I	0.839	1.00
101_R	105_P	0.837	1.00
111_K	120_T	0.837	1.00
119_L	122_E	0.829	1.00
55_L	58_S	0.828	1.00
156_E	188_H	0.827	1.00
127_R	130_K	0.826	1.00
110_M	113_L	0.821	1.00
30_K	180_G	0.820	1.00
118_A	175_G	0.819	1.00
87_V	136_K	0.817	1.00
6_V	51_I	0.815	1.00
14_H	22_N	0.815	1.00
171_Q	174_H	0.807	1.00
227_S	231_H	0.807	1.00
123_D	135_Q	0.804	1.00
97_L	110_M	0.803	1.00
113_L	116_L	0.801	1.00
91_L	96_I	0.798	1.00
13_K	46_T	0.797	1.00
174_H	178_D	0.791	1.00
33_I	174_H	0.789	1.00
57_P	70_D	0.787	1.00
11_V	50_M	0.786	1.00
214_P	224_Q	0.785	1.00
56_K	70_D	0.783	1.00
50_M	62_I	0.781	1.00
49_S	54_L	0.780	1.00
170_W	195_D	0.778	1.00
90_G	129_E	0.777	1.00
101_R	106_N	0.774	1.00
185_F	197_A	0.771	1.00
204_T	228_F	0.771	1.00
50_M	55_L	0.769	1.00
42_A	203_F	0.765	1.00
100_F	143_L	0.763	1.00
23_N	207_Q	0.763	1.00
14_H	20_A	0.763	1.00
120_T	123_D	0.762	1.00
81_M	144_A	0.761	1.00
96_I	128_A	0.758	1.00
37_L	193_A	0.753	1.00
214_P	218_R	0.752	1.00
74_V	78_I	0.752	1.00
131_L	135_Q	0.741	1.00
106_N	110_M	0.739	1.00
114_V	120_T	0.738	1.00
120_T	124_L	0.737	1.00
150_E	181_K	0.737	1.00
34_A	184_I	0.735	1.00
210_A	221_I	0.735	1.00
153_I	184_I	0.735	1.00
210_A	217_I	0.732	1.00
28_I	182_T	0.732	1.00
194_D	214_P	0.731	1.00
24_I	208_L	0.730	1.00
21_V	24_I	0.729	1.00
29_E	182_T	0.728	1.00
67_R	73_Q	0.722	1.00
14_H	18_K	0.722	1.00
171_Q	175_G	0.715	1.00
21_V	47_V	0.713	1.00
92_K	96_I	0.713	1.00
174_H	196_A	0.709	1.00
61_E	70_D	0.708	1.00
101_R	109_S	0.706	1.00
158_T	169_F	0.706	1.00
6_V	151_L	0.702	1.00
194_D	218_R	0.700	1.00
226_V	230_L	0.699	1.00
107_P	124_L	0.695	1.00
33_I	196_A	0.695	1.00
109_S	113_L	0.692	1.00
226_V	229_T	0.691	1.00
23_N	59_E	0.690	1.00
91_L	99_L	0.688	1.00
168_R	171_Q	0.685	1.00
73_Q	77_K	0.683	1.00
125_K	128_A	0.683	1.00
101_R	104_Y	0.678	1.00
151_L	182_T	0.677	1.00
111_K	114_V	0.676	1.00
208_L	211_D	0.676	1.00
113_L	145_L	0.671	1.00
133_G	138_R	0.668	1.00
235_S	238_R	0.663	1.00
19_T	23_N	0.661	1.00
28_I	184_I	0.660	1.00
28_I	151_L	0.658	1.00
14_H	17_R	0.658	1.00
20_A	46_T	0.649	1.00
202_F	217_I	0.648	1.00
37_L	202_F	0.646	1.00
228_F	231_H	0.644	1.00
171_Q	195_D	0.644	1.00
204_T	207_Q	0.643	1.00
15_F	55_L	0.641	1.00
78_I	151_L	0.640	1.00
217_I	226_V	0.640	1.00
190_L	218_R	0.635	1.00
79_G	147_G	0.634	1.00
108_L	111_K	0.634	1.00
210_A	222_Q	0.632	1.00
63_K	66_N	0.627	1.00
10_N	13_K	0.626	1.00
65_F	151_L	0.626	1.00
6_V	64_L	0.625	1.00
197_A	200_I	0.624	1.00
100_F	147_G	0.616	1.00
85_V	140_S	0.615	1.00
65_F	69_P	0.614	1.00
13_K	21_V	0.610	1.00
228_F	232_S	0.610	1.00
192_E	196_A	0.605	1.00
50_M	58_S	0.603	1.00
223_K	227_S	0.602	1.00
187_T	192_E	0.601	1.00
27_S	211_D	0.600	1.00
66_N	69_P	0.598	1.00
107_P	110_M	0.596	1.00
51_I	62_I	0.595	1.00
88_M	91_L	0.595	1.00
37_L	190_L	0.594	1.00
204_T	223_K	0.593	1.00
112_E	148_N	0.592	1.00
151_L	184_I	0.588	1.00
14_H	59_E	0.587	1.00
148_N	179_Q	0.586	1.00
99_L	103_Y	0.585	1.00
53_G	70_D	0.584	1.00
232_S	235_S	0.583	1.00
45_T	49_S	0.579	1.00
221_I	224_Q	0.577	1.00
52_L	78_I	0.577	1.00
64_L	74_V	0.572	1.00
185_F	196_A	0.570	1.00
118_A	122_E	0.566	1.00
5_A	64_L	0.557	1.00
64_L	77_K	0.556	1.00
61_E	71_D	0.554	1.00
100_F	103_Y	0.554	1.00
32_E	211_D	0.554	1.00
105_P	109_S	0.554	1.00
88_M	96_I	0.554	1.00
81_M	140_S	0.554	1.00
158_T	192_E	0.553	1.00
199_R	213_S	0.549	1.00
132_S	135_Q	0.549	1.00
13_K	16_Q	0.548	1.00
89_P	129_E	0.546	1.00
218_R	221_I	0.546	1.00
175_G	178_D	0.545	1.00
202_F	221_I	0.545	1.00
84_E	136_K	0.541	1.00
64_L	151_L	0.540	1.00
51_I	153_I	0.538	1.00
191_Q	195_D	0.536	1.00
197_A	214_P	0.535	1.00
113_L	119_L	0.535	1.00
31_G	182_T	0.535	1.00
106_N	109_S	0.534	1.00
165_S	168_R	0.533	1.00
40_N	156_E	0.533	1.00
205_E	228_F	0.533	1.00
193_A	197_A	0.532	1.00
33_I	198_Q	0.532	1.00
82_L	85_V	0.528	1.00
216_Q	222_Q	0.527	1.00
193_A	200_I	0.527	1.00
85_V	136_K	0.524	1.00
67_R	71_D	0.522	1.00
54_L	82_L	0.520	1.00
30_K	182_T	0.520	1.00
141_F	169_F	0.520	1.00
128_A	136_K	0.518	1.00
40_N	165_S	0.517	1.00
11_V	62_I	0.517	1.00
67_R	74_V	0.515	1.00
209_V	224_Q	0.515	1.00
5_A	151_L	0.514	1.00
5_A	182_T	0.514	1.00
100_F	104_Y	0.513	1.00
225_S	228_F	0.513	1.00
222_Q	227_S	0.511	1.00
19_T	59_E	0.511	1.00
49_S	80_V	0.506	1.00
7_T	66_N	0.504	1.00
89_P	136_K	0.501	1.00
221_I	229_T	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4yerA	2	0.9037	100	0.14	Contact Map
3tuiC	2	0.9867	100	0.182	Contact Map
1b0uA	2	0.7807	100	0.198	Contact Map
4u00A	1	0.7674	100	0.201	Contact Map
2oljA	2	0.7674	100	0.201	Contact Map
4ymuJ	2	0.7608	100	0.203	Contact Map
4mkiB	2	0.887	100	0.205	Contact Map
4rvcA	4	0.7741	100	0.207	Contact Map
4huqB	1	0.8738	100	0.209	Contact Map
3fvqA	2	0.9834	100	0.212	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0113 seconds.