GREMLIN Database
BGAL2 - Beta-galactosidase GanA
UniProt: O07012 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 672 (646)
Sequences: 1725 (1250)
Seq/√Len: 49.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
14_D58_D6.5401.00
47_E50_V6.0421.00
398_Q455_K6.0051.00
170_L189_W5.7061.00
547_V552_V5.3261.00
124_R231_E4.8861.00
329_L383_T4.5031.00
125_L128_E4.4041.00
35_S38_I4.3211.00
57_D130_Y4.1351.00
89_E114_V4.1071.00
109_C151_C4.0231.00
45_E49_G3.8091.00
60_F136_L3.7391.00
109_C149_C3.7201.00
157_A213_F3.6151.00
645_V668_V3.4961.00
155_Q194_S3.4001.00
151_C154_C3.3811.00
474_K509_A3.3661.00
172_T176_A3.3651.00
549_T570_H3.3541.00
440_I597_I3.2521.00
661_E664_E3.2341.00
48_E86_T3.2281.00
64_H133_H3.2021.00
305_L342_S3.1731.00
476_F481_G3.1611.00
187_N191_Q3.1601.00
149_C154_C3.0841.00
57_D129_R3.0181.00
51_Y121_H3.0111.00
473_L483_L2.9931.00
551_S569_S2.9441.00
94_N98_V2.9211.00
64_H135_A2.8861.00
21_D24_K2.8191.00
647_D650_T2.8171.00
87_Y118_K2.7941.00
13_L17_D2.7631.00
36_V60_F2.7281.00
477_T483_L2.7131.00
333_M383_T2.5851.00
85_Q191_Q2.5251.00
223_E263_H2.4841.00
20_A62_R2.4751.00
511_F577_A2.4571.00
111_T217_Q2.4181.00
124_R128_E2.4111.00
109_C154_C2.3741.00
467_E499_Y2.3651.00
616_V629_V2.3461.00
341_D392_G2.3061.00
569_S576_K2.3001.00
169_S172_T2.2831.00
475_A478_A2.2661.00
556_Y581_G2.2641.00
538_M582_A2.2521.00
229_L233_T2.2451.00
123_N228_P2.2281.00
75_P122_I2.1941.00
120_R228_P2.1861.00
451_F457_L2.1831.00
116_R220_S2.1771.00
60_F72_L2.1351.00
178_W353_G2.1271.00
223_E227_I2.1191.00
30_H385_E2.1181.00
613_G633_T2.0411.00
60_F70_V2.0371.00
124_R232_L2.0081.00
435_F458_I1.9920.99
84_S102_H1.9880.99
397_A441_P1.9870.99
233_T236_I1.9680.99
23_I66_I1.9680.99
19_L62_R1.9580.99
172_T175_H1.9380.99
230_K238_I1.9380.99
401_I444_V1.9230.99
513_V545_I1.9120.99
553_E578_Y1.8970.99
459_V483_L1.8910.99
357_K496_D1.8800.99
216_D259_K1.8670.99
24_K28_L1.8640.99
23_I62_R1.8490.99
552_V555_V1.8360.99
48_E87_Y1.8230.99
23_I63_I1.8210.99
27_K66_I1.8130.99
485_M511_F1.8070.99
26_M348_Y1.7940.99
516_L546_D1.7920.99
127_A229_L1.7900.99
161_W209_D1.7790.99
34_F63_I1.7650.99
20_A65_S1.7520.99
437_E590_R1.7450.99
330_L630_M1.7170.98
446_T449_Q1.7080.98
294_D432_Y1.7070.98
136_L236_I1.6930.98
253_Q412_E1.6860.98
438_H594_E1.6760.98
471_S475_A1.6750.98
256_D259_K1.6690.98
402_L469_T1.6540.98
298_S444_V1.6330.98
633_T637_Q1.6210.98
457_L481_G1.6030.98
457_L476_F1.5980.98
451_F469_T1.5930.97
660_M666_R1.5740.97
474_K478_A1.5570.97
150_H194_S1.5530.97
456_L596_L1.5490.97
261_A299_L1.5450.97
64_H70_V1.5380.97
551_S571_E1.5350.97
269_W293_N1.5330.97
576_K599_D1.5310.97
170_L192_I1.5290.97
114_V118_K1.5150.97
239_T268_S1.5130.97
399_T440_I1.5040.96
379_K383_T1.5040.96
550_A570_H1.5000.96
51_Y125_L1.4990.96
160_E163_K1.4880.96
43_A180_P1.4780.96
53_F57_D1.4750.96
170_L187_N1.4740.96
592_F596_L1.4720.96
510_I572_Y1.4690.96
621_D624_N1.4620.96
121_H125_L1.4600.96
85_Q188_D1.4600.96
465_I489_S1.4540.96
459_V462_L1.4520.96
620_Q625_D1.4470.96
161_W216_D1.4450.96
336_I343_V1.4400.95
155_Q159_R1.4320.95
167_D171_K1.4250.95
268_S307_M1.4220.95
114_V117_E1.4130.95
162_L173_L1.4090.95
478_A572_Y1.4010.95
443_D454_Y1.4000.95
597_I602_L1.3990.95
596_L600_L1.3950.95
43_A185_T1.3870.94
314_V320_N1.3870.94
291_F444_V1.3850.94
89_E112_S1.3820.94
64_H134_P1.3790.94
226_I263_H1.3770.94
136_L233_T1.3740.94
614_V660_M1.3730.94
205_G497_L1.3700.94
45_E51_Y1.3690.94
93_V99_K1.3650.94
60_F135_A1.3650.94
482_T578_Y1.3640.94
229_L232_L1.3580.94
28_L369_P1.3470.93
61_E133_H1.3420.93
219_I259_K1.3390.93
438_H590_R1.3380.93
63_I68_G1.3360.93
83_L90_V1.3320.93
241_N270_D1.3280.93
636_K659_T1.3140.93
466_S469_T1.3110.93
552_V565_P1.3100.92
20_A58_D1.3090.92
402_L459_V1.3020.92
618_A625_D1.3010.92
243_M252_Y1.3000.92
76_S119_T1.2890.92
61_E65_S1.2740.91
485_M577_A1.2720.91
138_M237_P1.2700.91
123_N224_N1.2680.91
120_R224_N1.2570.91
465_I507_L1.2550.91
37_G55_W1.2540.91
312_S373_V1.2520.91
536_Y591_D1.2460.90
595_G599_D1.2440.90
567_V580_I1.2420.90
85_Q190_S1.2420.90
402_L445_I1.2370.90
467_E471_S1.2280.90
9_P12_W1.2240.90
329_L333_M1.2220.90
372_R517_E1.2140.89
138_M266_A1.2130.89
647_D651_G1.2120.89
116_R224_N1.2060.89
23_I68_G1.1980.89
484_V580_I1.1920.88
28_L378_A1.1900.88
433_R437_E1.1860.88
410_A463_Y1.1850.88
431_H486_T1.1800.88
427_T583_R1.1690.87
243_M269_W1.1670.87
374_F378_A1.1660.87
647_D666_R1.1650.87
94_N100_Q1.1620.87
165_K209_D1.1600.87
69_R137_L1.1580.87
181_F351_S1.1560.87
142_S225_E1.1560.87
545_I581_G1.1510.87
493_N497_L1.1490.86
60_F133_H1.1480.86
636_K661_E1.1450.86
456_L476_F1.1450.86
556_Y566_A1.1440.86
473_L510_I1.1440.86
569_S578_Y1.1440.86
382_E386_R1.1410.86
536_Y588_F1.1320.86
138_M305_L1.1290.86
326_G376_E1.1270.85
278_D522_Y1.1260.85
266_A305_L1.1240.85
83_L118_K1.1210.85
33_T137_L1.1190.85
173_L177_W1.1170.85
584_L588_F1.1100.85
118_K121_H1.1060.84
81_A85_Q1.1060.84
208_L464_L1.0910.83
614_V639_V1.0900.83
62_R66_I1.0870.83
24_K66_I1.0850.83
106_H148_D1.0850.83
383_T649_M1.0810.83
423_R426_Q1.0800.83
459_V485_M1.0780.83
163_K189_W1.0780.83
510_I577_A1.0750.83
219_I263_H1.0750.83
157_A220_S1.0740.83
106_H122_I1.0730.82
329_L379_K1.0730.82
400_A457_L1.0720.82
163_K188_D1.0710.82
106_H147_G1.0670.82
585_E588_F1.0650.82
514_E546_D1.0640.82
401_I435_F1.0620.82
53_F130_Y1.0580.82
128_E131_G1.0570.81
242_F264_V1.0550.81
145_Y222_Y1.0510.81
618_A627_I1.0490.81
131_G233_T1.0490.81
113_K153_L1.0490.81
273_P331_S1.0460.81
571_E576_K1.0440.81
479_D574_Q1.0370.80
636_K662_K1.0340.80
38_I73_A1.0340.80
478_A574_Q1.0330.80
508_Q548_K1.0330.80
658_L668_V1.0290.80
37_G75_P1.0280.80
536_Y585_E1.0270.80
100_Q199_G1.0230.79
527_N531_Y1.0230.79
466_S494_E1.0220.79
362_V377_V1.0220.79
452_S479_D1.0150.79
379_K382_E1.0100.78
156_H190_S1.0060.78
456_L597_I1.0060.78
615_S632_F1.0050.78
90_V114_V1.0040.78
61_E70_V1.0040.78
75_P126_L1.0040.78
226_I230_K1.0040.78
462_L465_I1.0020.78
528_A557_Q1.0020.78
210_W214_V1.0010.78
212_R406_E1.0010.78
293_N335_M0.9980.78
457_L473_L0.9940.77
482_T600_L0.9930.77
157_A217_Q0.9930.77
141_I229_L0.9920.77
478_A571_E0.9890.77
437_E586_D0.9880.77
60_F63_I0.9840.77
165_K495_H0.9830.77
58_D62_R0.9790.76
322_A560_F0.9790.76
128_E232_L0.9740.76
40_A43_A0.9730.76
219_I260_F0.9720.76
14_D19_L0.9700.76
469_T472_R0.9690.75
544_V560_F0.9630.75
10_D37_G0.9600.75
638_L659_T0.9600.75
38_I140_H0.9590.75
27_K379_K0.9580.75
365_H498_T0.9570.75
117_E121_H0.9570.75
127_A232_L0.9510.74
216_D219_I0.9510.74
81_A102_H0.9510.74
287_M432_Y0.9490.74
70_V135_A0.9440.74
152_D193_E0.9410.73
513_V568_T0.9410.73
19_L23_I0.9400.73
33_T344_L0.9400.73
3_H381_G0.9350.73
21_D25_L0.9310.73
484_V593_Y0.9310.73
164_S220_S0.9250.72
432_Y442_V0.9230.72
475_A479_D0.9230.72
456_L600_L0.9200.72
60_F64_H0.9200.72
642_D645_V0.9200.72
375_Q378_A0.9190.72
181_F346_F0.9180.71
332_S380_V0.9150.71
79_R84_S0.9140.71
79_R108_H0.9140.71
93_V152_D0.9090.71
13_L18_I0.9080.71
36_V70_V0.9080.71
526_R537_E0.9060.70
259_K262_K0.9050.70
528_A558_E0.9040.70
491_V518_T0.9030.70
348_Y363_V0.9020.70
270_D307_M0.8990.70
40_A55_W0.8960.70
8_N38_I0.8950.69
5_G35_S0.8950.69
144_E308_E0.8950.69
396_P453_P0.8950.69
482_T576_K0.8920.69
311_P359_H0.8920.69
294_D338_H0.8910.69
646_K651_G0.8880.69
258_S444_V0.8860.69
401_I442_V0.8820.68
519_D561_Y0.8780.68
476_F483_L0.8780.68
499_Y506_D0.8770.68
258_S446_T0.8760.68
26_M31_T0.8760.68
474_K572_Y0.8740.68
340_S343_V0.8720.67
207_N413_D0.8710.67
463_Y496_D0.8700.67
309_C331_S0.8700.67
33_T71_I0.8670.67
294_D297_R0.8670.67
439_D610_H0.8660.67
109_C153_L0.8660.67
101_L196_S0.8650.67
329_L649_M0.8650.67
647_D668_V0.8650.67
209_D495_H0.8620.67
401_I458_I0.8610.66
43_A52_Q0.8600.66
120_R124_R0.8590.66
71_I342_S0.8570.66
163_K493_N0.8560.66
476_F482_T0.8540.66
179_T184_H0.8500.65
71_I305_L0.8500.65
96_S197_P0.8490.65
44_L126_L0.8490.65
45_E50_V0.8480.65
382_E385_E0.8460.65
658_L666_R0.8460.65
23_I59_I0.8450.65
654_L658_L0.8450.65
47_E191_Q0.8440.65
131_G232_L0.8430.65
156_H159_R0.8420.65
641_F645_V0.8410.65
44_L53_F0.8400.65
13_L19_L0.8400.65
437_E612_K0.8380.64
353_G497_L0.8380.64
37_G40_A0.8370.64
403_Y408_H0.8320.64
274_V317_H0.8310.64
480_G575_G0.8290.64
179_T186_F0.8280.63
327_M330_L0.8270.63
530_S555_V0.8260.63
204_H354_S0.8230.63
180_P353_G0.8230.63
446_T472_R0.8210.63
73_A140_H0.8210.63
593_Y596_L0.8200.63
378_A382_E0.8190.63
176_A495_H0.8180.62
35_S140_H0.8160.62
164_S167_D0.8160.62
291_F428_L0.8160.62
297_R443_D0.8150.62
470_V510_I0.8120.62
161_W166_Y0.8110.62
331_S632_F0.8100.62
8_N140_H0.8100.62
424_Y428_L0.8080.62
35_S73_A0.8070.61
352_R500_T0.8070.61
222_Y226_I0.8060.61
140_H225_E0.8060.61
448_E472_R0.8060.61
314_V359_H0.8050.61
372_R376_E0.8040.61
400_A454_Y0.8040.61
39_F77_G0.8030.61
309_C346_F0.8020.61
477_T510_I0.8020.61
10_D180_P0.8010.61
544_V564_T0.8000.61
36_V73_A0.7990.61
605_V616_V0.7990.61
436_W441_P0.7980.61
215_T219_I0.7970.60
393_T621_D0.7950.60
156_H160_E0.7940.60
266_A342_S0.7910.60
90_V112_S0.7900.60
455_K476_F0.7900.60
514_E548_K0.7900.60
358_L491_V0.7890.60
629_V658_L0.7880.60
29_S374_F0.7880.60
588_F592_F0.7870.59
273_P309_C0.7860.59
652_D666_R0.7840.59
641_F654_L0.7840.59
253_Q408_H0.7820.59
233_T237_P0.7800.59
520_T541_Y0.7760.58
48_E118_K0.7750.58
166_Y209_D0.7740.58
184_H203_L0.7730.58
148_D214_V0.7710.58
484_V596_L0.7700.58
258_S449_Q0.7680.58
515_P543_T0.7670.58
87_Y114_V0.7660.57
64_H67_G0.7650.57
584_L592_F0.7630.57
17_D602_L0.7620.57
186_F206_L0.7610.57
301_Q449_Q0.7610.57
389_E626_Y0.7570.57
176_A493_N0.7560.56
18_I367_N0.7540.56
43_A55_W0.7540.56
456_L602_L0.7540.56
111_T154_C0.7510.56
173_L192_I0.7500.56
368_S374_F0.7500.56
338_H615_S0.7490.56
580_I584_L0.7490.56
484_V614_V0.7490.56
11_Q347_Q0.7490.56
477_T573_Q0.7480.56
267_I299_L0.7450.55
578_Y596_L0.7450.55
180_P185_T0.7420.55
455_K479_D0.7410.55
47_E187_N0.7410.55
110_L218_T0.7400.55
227_I231_E0.7370.54
312_S331_S0.7340.54
75_P142_S0.7300.54
568_T577_A0.7300.54
450_D453_P0.7290.54
61_E135_A0.7280.54
6_D11_Q0.7280.54
140_H323_K0.7270.53
490_G505_P0.7260.53
431_H580_I0.7240.53
48_E51_Y0.7230.53
328_N345_Y0.7230.53
223_E262_K0.7220.53
485_M489_S0.7210.53
115_Y142_S0.7210.53
463_Y492_V0.7190.53
567_V581_G0.7180.53
534_Q591_D0.7180.53
108_H147_G0.7170.52
390_V628_F0.7150.52
124_R228_P0.7120.52
81_A187_N0.7120.52
211_R412_E0.7120.52
456_L484_V0.7120.52
531_Y534_Q0.7120.52
619_R628_F0.7110.52
6_D346_F0.7100.52
154_C217_Q0.7090.52
406_E616_V0.7060.51
473_L515_P0.7030.51
4_G7_Y0.7030.51
140_H347_Q0.7020.51
471_S474_K0.7020.51
142_S221_F0.7020.51
34_F68_G0.7000.51
154_C210_W0.6990.51
545_I556_Y0.6980.51
8_N73_A0.6980.51
27_K67_G0.6980.51
630_M665_V0.6980.51
310_T331_S0.6970.50
646_K650_T0.6970.50
47_E188_D0.6970.50
468_D471_S0.6960.50
480_G573_Q0.6960.50
4_G10_D0.6960.50
107_N147_G0.6950.50
20_A66_I0.6940.50
57_D61_E0.6930.50
662_K667_I0.6930.50
37_G126_L0.6910.50
310_T317_H0.6900.50
120_R227_I0.6890.50
92_R108_H0.6890.50
36_V59_I0.6890.50
77_G108_H0.6870.49
290_G294_D0.6850.49
7_Y22_D0.6850.49
504_H508_Q0.6840.49
188_D453_P0.6840.49
527_N538_M0.6830.49
387_L390_V0.6830.49
29_S381_G0.6820.49
120_R123_N0.6820.49
153_L156_H0.6820.49
369_P374_F0.6820.49
89_E153_L0.6810.49
327_M331_S0.6800.49
477_T577_A0.6800.49
48_E121_H0.6800.49
311_P360_G0.6790.49
654_L668_V0.6790.49
587_Q652_D0.6770.48
547_V550_A0.6770.48
558_E562_A0.6770.48
545_I579_F0.6760.48
528_A535_I0.6740.48
157_A160_E0.6740.48
141_I222_Y0.6730.48
138_M236_I0.6730.48
222_Y264_V0.6730.48
324_R559_D0.6720.48
350_K364_D0.6720.48
101_L194_S0.6710.48
429_Q432_Y0.6710.48
108_H331_S0.6710.48
505_P508_Q0.6700.48
323_K347_Q0.6690.48
54_E129_R0.6690.48
242_F261_A0.6680.47
167_D172_T0.6650.47
92_R99_K0.6640.47
23_I34_F0.6640.47
438_H597_I0.6620.47
549_T552_V0.6620.47
86_T191_Q0.6620.47
467_E506_D0.6620.47
313_A401_I0.6600.47
209_D212_R0.6590.47
544_V561_Y0.6590.47
366_D371_N0.6590.47
128_E132_H0.6570.46
627_I645_V0.6560.46
92_R147_G0.6560.46
315_N359_H0.6550.46
597_I601_S0.6540.46
159_R190_S0.6520.46
243_M257_Y0.6520.46
163_K170_L0.6520.46
227_I238_I0.6520.46
646_K655_S0.6510.46
90_V290_G0.6510.46
188_D192_I0.6490.46
217_Q220_S0.6490.46
288_K429_Q0.6470.45
484_V592_F0.6460.45
473_L624_N0.6450.45
223_E226_I0.6450.45
530_S557_Q0.6440.45
402_L442_V0.6440.45
38_I225_E0.6440.45
476_F479_D0.6430.45
110_L217_Q0.6430.45
123_N221_F0.6430.45
319_V421_T0.6420.45
644_S653_I0.6420.45
329_L665_V0.6410.45
241_N307_M0.6410.45
333_M387_L0.6410.45
590_R593_Y0.6400.45
160_E164_S0.6400.45
290_G617_Q0.6390.45
160_E190_S0.6390.45
435_F593_Y0.6380.44
31_T34_F0.6380.44
14_D175_H0.6380.44
330_L632_F0.6370.44
271_A330_L0.6370.44
438_H593_Y0.6370.44
155_Q193_E0.6360.44
229_L238_I0.6350.44
591_D594_E0.6340.44
664_E668_V0.6340.44
610_H616_V0.6330.44
110_L260_F0.6320.44
105_R182_W0.6320.44
133_H136_L0.6310.44
65_S636_K0.6290.44
453_P478_A0.6290.44
147_G200_E0.6290.44
462_L469_T0.6280.43
8_N11_Q0.6280.43
289_V292_I0.6280.43
5_G38_I0.6280.43
273_P335_M0.6280.43
597_I600_L0.6280.43
512_G568_T0.6280.43
230_K234_P0.6270.43
637_Q640_T0.6260.43
262_K448_E0.6250.43
377_V381_G0.6250.43
77_G106_H0.6250.43
311_P350_K0.6240.43
345_Y380_V0.6230.43
567_V592_F0.6230.43
408_H412_E0.6220.43
79_R107_N0.6220.43
83_L142_S0.6220.43
60_F236_I0.6210.43
322_A544_V0.6210.43
644_S655_S0.6210.43
287_M429_Q0.6200.43
587_Q636_K0.6200.43
152_D155_Q0.6190.43
578_Y592_F0.6180.42
301_Q453_P0.6180.42
65_S160_E0.6180.42
19_L59_I0.6160.42
420_A660_M0.6160.42
184_H198_I0.6150.42
71_I138_M0.6150.42
167_D571_E0.6140.42
509_A548_K0.6140.42
375_Q516_L0.6140.42
40_A44_L0.6130.42
500_T503_W0.6130.42
491_V503_W0.6130.42
445_I457_L0.6130.42
3_H345_Y0.6120.42
32_N545_I0.6120.42
538_M584_L0.6110.42
115_Y221_F0.6110.42
349_R367_N0.6110.42
7_Y12_W0.6100.42
55_W208_L0.6100.42
474_K510_I0.6100.42
193_E206_L0.6090.42
75_P225_E0.6080.41
430_Q586_D0.6080.41
8_N35_S0.6070.41
106_H115_Y0.6060.41
64_H69_R0.6060.41
5_G138_M0.6050.41
469_T473_L0.6050.41
21_D367_N0.6030.41
112_S153_L0.6030.41
45_E75_P0.6020.41
106_H142_S0.6020.41
357_K463_Y0.6020.41
393_T620_Q0.6000.41
178_W363_V0.6000.41
336_I384_L0.5990.41
181_F315_N0.5990.41
565_P568_T0.5990.41
218_T255_L0.5980.40
228_P232_L0.5970.40
119_T224_N0.5970.40
309_C335_M0.5960.40
33_T138_M0.5950.40
214_V254_G0.5940.40
379_K649_M0.5930.40
510_I570_H0.5930.40
399_T597_I0.5930.40
396_P620_Q0.5930.40
122_I225_E0.5920.40
136_L234_P0.5920.40
399_T458_I0.5910.40
17_D635_E0.5900.40
5_G8_N0.5900.40
227_I263_H0.5900.40
33_T69_R0.5890.40
430_Q583_R0.5890.40
515_P545_I0.5890.40
32_N381_G0.5890.40
478_A570_H0.5880.40
257_Y269_W0.5870.39
453_P655_S0.5870.39
252_Y269_W0.5860.39
477_T480_G0.5860.39
48_E126_L0.5850.39
230_K235_D0.5840.39
203_L355_S0.5840.39
329_L664_E0.5840.39
408_H424_Y0.5840.39
38_I142_S0.5830.39
115_Y126_L0.5830.39
350_K359_H0.5820.39
194_S210_W0.5820.39
617_Q632_F0.5810.39
347_Q359_H0.5810.39
270_D346_F0.5810.39
427_T431_H0.5800.39
8_N40_A0.5800.39
14_D20_A0.5790.39
143_N241_N0.5790.39
414_A488_I0.5780.39
529_V538_M0.5770.38
227_I466_S0.5770.38
478_A599_D0.5770.38
586_D590_R0.5770.38
239_T266_A0.5770.38
587_Q598_T0.5760.38
23_I70_V0.5760.38
78_A147_G0.5760.38
525_D529_V0.5750.38
305_L344_L0.5740.38
59_I62_R0.5720.38
431_H458_I0.5710.38
629_V668_V0.5700.38
262_K636_K0.5700.38
271_A335_M0.5690.38
84_S91_L0.5690.38
242_F258_S0.5690.38
122_I126_L0.5690.38
579_F631_N0.5690.38
42_S543_T0.5690.38
222_Y263_H0.5680.38
31_T348_Y0.5680.38
386_R603_S0.5670.37
12_W349_R0.5670.37
100_Q104_G0.5660.37
84_S106_H0.5650.37
191_Q211_R0.5650.37
186_F191_Q0.5640.37
24_K136_L0.5640.37
83_L89_E0.5640.37
538_M566_A0.5630.37
177_W206_L0.5630.37
149_C255_L0.5630.37
5_G33_T0.5620.37
485_M507_L0.5620.37
315_N320_N0.5620.37
398_Q603_S0.5620.37
428_L444_V0.5610.37
527_N530_S0.5610.37
36_V61_E0.5610.37
550_A568_T0.5610.37
123_N145_Y0.5600.37
3_H328_N0.5600.37
435_F597_I0.5600.37
198_I202_G0.5600.37
175_H537_E0.5600.37
554_A567_V0.5600.37
127_A139_W0.5590.37
27_K169_S0.5590.37
404_D407_N0.5580.37
37_G44_L0.5580.37
110_L299_L0.5580.37
67_G571_E0.5580.37
13_L58_D0.5580.37
262_K574_Q0.5570.37
21_D390_V0.5570.37
309_C332_S0.5570.37
537_E585_E0.5570.37
329_L380_V0.5560.36
104_G198_I0.5560.36
169_S445_I0.5550.36
229_L234_P0.5550.36
243_M293_N0.5550.36
375_Q379_K0.5540.36
485_M545_I0.5540.36
403_Y428_L0.5540.36
178_W203_L0.5540.36
551_S555_V0.5540.36
465_I469_T0.5540.36
427_T430_Q0.5530.36
593_Y597_I0.5530.36
390_V393_T0.5530.36
273_P338_H0.5530.36
8_N225_E0.5530.36
269_W335_M0.5520.36
38_I147_G0.5520.36
386_R647_D0.5510.36
35_S71_I0.5510.36
96_S567_V0.5510.36
38_I323_K0.5510.36
63_I70_V0.5510.36
89_E117_E0.5500.36
244_A292_I0.5500.36
84_S90_V0.5500.36
128_E586_D0.5500.36
261_A493_N0.5500.36
478_A551_S0.5490.36
312_S357_K0.5490.36
4_G22_D0.5480.36
421_T523_P0.5480.36
459_V477_T0.5470.36
271_A334_Q0.5470.36
484_V567_V0.5470.36
35_S347_Q0.5460.36
38_I488_I0.5460.36
147_G199_G0.5450.35
120_R231_E0.5450.35
42_S185_T0.5440.35
187_N190_S0.5440.35
11_Q351_S0.5430.35
152_D196_S0.5430.35
167_D591_D0.5430.35
271_A293_N0.5420.35
51_Y667_I0.5420.35
255_L260_F0.5420.35
319_V523_P0.5420.35
23_I27_K0.5410.35
311_P315_N0.5410.35
386_R648_I0.5400.35
427_T487_Y0.5400.35
40_A180_P0.5380.35
5_G73_A0.5360.35
641_F644_S0.5360.35
428_L435_F0.5360.35
341_D619_R0.5360.35
559_D562_A0.5360.35
143_N308_E0.5350.34
644_S658_L0.5350.34
603_S612_K0.5350.34
320_N359_H0.5350.34
6_D12_W0.5350.34
447_K472_R0.5340.34
412_E423_R0.5340.34
416_G492_V0.5340.34
52_Q524_K0.5340.34
488_I492_V0.5340.34
533_S562_A0.5330.34
327_M663_Y0.5330.34
613_G616_V0.5330.34
291_F363_V0.5320.34
316_W320_N0.5320.34
289_V334_Q0.5310.34
646_K653_I0.5310.34
538_M543_T0.5300.34
4_G9_P0.5290.34
458_I667_I0.5290.34
650_T668_V0.5290.34
38_I347_Q0.5290.34
178_W497_L0.5290.34
9_P39_F0.5290.34
451_F472_R0.5280.34
34_F38_I0.5280.34
405_W408_H0.5280.34
294_D442_V0.5280.34
383_T386_R0.5280.34
317_H320_N0.5270.34
70_V584_L0.5270.34
82_W356_E0.5270.34
289_V335_M0.5260.34
653_I668_V0.5260.34
399_T602_L0.5250.34
104_G200_E0.5240.33
8_N142_S0.5230.33
210_W345_Y0.5230.33
328_N332_S0.5230.33
453_P539_K0.5220.33
401_I622_Q0.5220.33
527_N559_D0.5220.33
478_A602_L0.5210.33
215_T409_W0.5210.33
434_T589_Q0.5210.33
395_R439_D0.5210.33
92_R148_D0.5210.33
170_L190_S0.5190.33
399_T456_L0.5190.33
290_G334_Q0.5180.33
63_I66_I0.5180.33
14_D17_D0.5180.33
142_S357_K0.5170.33
190_S594_E0.5170.33
603_S607_P0.5160.33
478_A528_A0.5160.33
233_T320_N0.5160.33
107_N184_H0.5160.33
28_L87_Y0.5150.33
90_V142_S0.5150.33
294_D550_A0.5150.33
114_V153_L0.5150.33
90_V221_F0.5150.33
590_R594_E0.5150.33
56_L243_M0.5150.33
108_H142_S0.5150.33
219_I222_Y0.5150.33
214_V217_Q0.5140.33
436_W439_D0.5140.33
304_F360_G0.5140.33
228_P234_P0.5130.33
72_L126_L0.5120.32
461_M487_Y0.5110.32
47_E160_E0.5110.32
255_L405_W0.5110.32
580_I589_Q0.5110.32
650_T659_T0.5100.32
145_Y221_F0.5100.32
182_W356_E0.5090.32
229_L236_I0.5090.32
499_Y507_L0.5090.32
397_A443_D0.5080.32
566_A582_A0.5080.32
41_W45_E0.5080.32
489_S507_L0.5080.32
335_M340_S0.5070.32
79_R106_H0.5070.32
120_R402_L0.5070.32
577_A596_L0.5070.32
595_G653_I0.5070.32
170_L188_D0.5060.32
159_R193_E0.5060.32
259_K448_E0.5060.32
659_T666_R0.5060.32
226_I238_I0.5060.32
152_D398_Q0.5050.32
296_Y299_L0.5050.32
35_S305_L0.5050.32
54_E652_D0.5050.32
396_P399_T0.5050.32
75_P106_H0.5030.32
567_V578_Y0.5020.32
229_L594_E0.5020.32
89_E127_A0.5020.32
85_Q102_H0.5010.31
260_F498_T0.5010.31
244_A269_W0.5010.31
271_A309_C0.5000.31
39_F349_R0.5000.31
440_I604_P0.5000.31
83_L114_V0.5000.31
581_G584_L0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4oifA 3 0.997 100 0.252 Contact Map
3ttyA 4 0.9702 100 0.256 Contact Map
4uozA 3 0.9658 100 0.265 Contact Map
1kwgA 3 0.9375 100 0.275 Contact Map
4d1iA 4 0.6949 100 0.668 Contact Map
3u7vA 3 0.6443 100 0.685 Contact Map
2zuvA 2 0.8393 100 0.699 Contact Map
1wdpA 1 0.5863 100 0.71 Contact Map
1fa2A 3 0.5908 100 0.743 Contact Map
3og2A 1 0.6295 100 0.75 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0246 seconds.