GREMLIN Database
GANQ - Putative arabinogalactan oligomer transport system permease protein GanQ
UniProt: O07011 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 283 (253)
Sequences: 69167 (45494)
Seq/√Len: 2860.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
187_R191_Q4.0871.00
77_V81_K3.2231.00
179_K188_I3.0131.00
164_K168_D3.0011.00
38_S60_Y2.7951.00
75_W234_G2.6301.00
103_R175_D2.6151.00
74_Q77_V2.6141.00
184_S187_R2.5571.00
178_A188_I2.5531.00
175_D193_I2.4991.00
85_F148_I2.4931.00
89_G152_I2.4391.00
166_Y200_M2.4381.00
229_Y237_N2.4241.00
58_D61_K2.4231.00
61_K65_A2.3811.00
73_V77_V2.3711.00
87_M205_A2.3061.00
185_S188_I2.2761.00
186_T190_F2.2681.00
58_D62_E2.2571.00
163_M201_A2.2561.00
246_S249_T2.1461.00
106_F109_R2.0831.00
187_R190_F2.0571.00
95_T189_F2.0441.00
183_A187_R2.0191.00
159_N204_V1.9871.00
102_S168_D1.9561.00
167_M197_S1.9491.00
174_L196_L1.9071.00
178_A183_A1.8711.00
32_L36_G1.8351.00
91_L205_A1.8121.00
95_T197_S1.8081.00
113_L164_K1.7941.00
36_G40_N1.7871.00
74_Q78_N1.7371.00
179_K185_S1.7271.00
83_S209_F1.7001.00
94_V159_N1.6941.00
175_D188_I1.6761.00
81_K85_F1.6501.00
95_T163_M1.6281.00
86_T212_P1.6191.00
97_T160_T1.6081.00
101_F160_T1.5671.00
62_E249_T1.5491.00
175_D179_K1.5361.00
17_Y21_A1.4931.00
216_F220_S1.4761.00
105_R109_R1.4671.00
234_G238_L1.4561.00
108_G111_Y1.4321.00
29_Y33_W1.4271.00
172_M175_D1.4261.00
62_E65_A1.4221.00
35_A255_L1.4191.00
57_F61_K1.4151.00
159_N208_G1.4081.00
67_K71_Q1.4061.00
98_A163_M1.3961.00
82_I230_T1.3911.00
102_S164_K1.3841.00
56_T59_H1.3811.00
203_V207_N1.3721.00
194_L201_A1.3711.00
167_M193_I1.3481.00
216_F236_F1.3381.00
33_W37_A1.3281.00
92_L96_F1.3191.00
90_S208_G1.3081.00
103_R172_M1.3001.00
144_H228_S1.2941.00
163_M204_V1.2941.00
142_N146_L1.2921.00
225_T228_S1.2761.00
172_M176_E1.2671.00
71_Q74_Q1.2611.00
178_A192_I1.2491.00
95_T201_A1.2401.00
218_L222_I1.2311.00
99_Y167_M1.2191.00
266_I270_K1.2141.00
238_L246_S1.2081.00
226_P229_Y1.2071.00
229_Y234_G1.2021.00
79_S231_L1.1921.00
173_D176_E1.1791.00
150_L222_I1.1751.00
88_A92_L1.1721.00
111_Y114_T1.1681.00
85_F88_A1.1591.00
170_I196_L1.1491.00
21_A25_V1.1451.00
78_N81_K1.1421.00
184_S188_I1.1421.00
198_K202_A1.1191.00
237_N241_D1.1161.00
147_L219_S1.1151.00
91_L201_A1.1111.00
11_I15_F1.1101.00
60_Y255_L1.1041.00
44_S54_H1.1041.00
12_R16_S1.0961.00
34_T255_L1.0941.00
62_E66_G1.0881.00
111_Y115_L1.0711.00
156_I160_T1.0711.00
14_L18_L1.0681.00
270_K273_V1.0651.00
148_I152_I1.0651.00
238_L244_G1.0541.00
41_P44_S1.0541.00
143_S146_L1.0531.00
140_M145_W1.0481.00
163_M200_M1.0481.00
89_G148_I1.0431.00
99_Y189_F1.0421.00
230_T233_V1.0321.00
215_D218_L1.0321.00
85_F89_G1.0271.00
66_G71_Q1.0261.00
162_L204_V1.0251.00
102_S167_M1.0231.00
64_F73_V1.0211.00
175_D185_S1.0201.00
229_Y233_V1.0191.00
196_L199_P1.0101.00
80_M84_L1.0071.00
86_T90_S1.0011.00
11_I14_L1.0011.00
96_F100_A0.9971.00
219_S230_T0.9941.00
86_T151_Y0.9931.00
14_L17_Y0.9871.00
33_W36_G0.9821.00
99_Y185_S0.9801.00
133_V137_I0.9761.00
188_I191_Q0.9731.00
183_A188_I0.9711.00
109_R168_D0.9611.00
76_Y231_L0.9601.00
16_S20_L0.9541.00
215_D219_S0.9471.00
131_L222_I0.9321.00
267_M271_N0.9211.00
42_G46_I0.9201.00
98_A102_S0.9191.00
13_L17_Y0.9181.00
81_K84_L0.9181.00
151_Y212_P0.9141.00
239_V250_F0.9121.00
88_A205_A0.9101.00
84_L88_A0.8991.00
234_G253_G0.8951.00
117_L161_Y0.8951.00
76_Y80_M0.8861.00
197_S200_M0.8831.00
261_V265_F0.8831.00
107_K110_K0.8811.00
166_Y197_S0.8791.00
37_A251_A0.8781.00
89_G92_L0.8761.00
24_A28_V0.8761.00
159_N163_M0.8751.00
198_K201_A0.8711.00
189_F194_L0.8661.00
94_V160_T0.8641.00
38_S42_G0.8611.00
131_L150_L0.8611.00
40_N44_S0.8601.00
163_M197_S0.8591.00
90_S94_V0.8571.00
37_A40_N0.8561.00
63_L256_L0.8541.00
59_H248_T0.8531.00
220_S233_V0.8461.00
234_G237_N0.8461.00
86_T148_I0.8461.00
110_K113_L0.8451.00
90_S155_L0.8451.00
81_K144_H0.8371.00
39_F55_P0.8361.00
190_F194_L0.8311.00
72_Y253_G0.8291.00
101_F113_L0.8281.00
43_N46_I0.8271.00
142_N225_T0.8241.00
100_A106_F0.8201.00
132_F136_Q0.8191.00
208_G212_P0.8151.00
39_F56_T0.8131.00
188_I193_I0.8121.00
98_A167_M0.8071.00
136_Q141_I0.8031.00
124_Q154_G0.8021.00
236_F240_N0.7991.00
34_T251_A0.7971.00
64_F67_K0.7941.00
77_V80_M0.7921.00
82_I151_Y0.7921.00
238_L253_G0.7831.00
183_A191_Q0.7821.00
174_L192_I0.7811.00
98_A160_T0.7791.00
263_V267_M0.7761.00
85_F152_I0.7741.00
90_S159_N0.7701.00
75_W78_N0.7681.00
185_S189_F0.7651.00
128_L221_T0.7601.00
238_L249_T0.7501.00
249_T253_G0.7491.00
29_Y32_L0.7481.00
150_L218_L0.7461.00
62_E246_S0.7461.00
235_L253_G0.7451.00
147_L151_Y0.7431.00
83_S87_M0.7421.00
189_F193_I0.7421.00
142_N145_W0.7411.00
170_I197_S0.7321.00
51_I54_H0.7311.00
128_L217_V0.7271.00
198_K271_N0.7261.00
87_M209_F0.7251.00
37_A41_P0.7221.00
75_W231_L0.7181.00
231_L257_I0.7171.00
79_S232_P0.7161.00
101_F112_A0.7161.00
61_K64_F0.7151.00
257_I261_V0.7151.00
163_M167_M0.7141.00
73_V76_Y0.7141.00
55_P58_D0.7121.00
117_L120_Q0.7111.00
215_D230_T0.7081.00
91_L163_M0.7061.00
124_Q217_V0.7041.00
101_F164_K0.6961.00
41_P54_H0.6951.00
15_F18_L0.6931.00
94_V163_M0.6921.00
40_N52_P0.6881.00
172_M179_K0.6881.00
135_A141_I0.6861.00
251_A255_L0.6851.00
127_A153_G0.6841.00
18_L21_A0.6841.00
241_D244_G0.6811.00
87_M91_L0.6761.00
201_A204_V0.6751.00
193_I196_L0.6741.00
34_T254_A0.6721.00
90_S212_P0.6711.00
23_M27_I0.6701.00
15_F19_L0.6681.00
82_I147_L0.6671.00
59_H62_E0.6661.00
177_S181_D0.6661.00
141_I146_L0.6641.00
93_C152_I0.6631.00
233_V237_N0.6571.00
56_T60_Y0.6571.00
97_T156_I0.6561.00
138_L141_I0.6461.00
20_L24_A0.6451.00
82_I148_I0.6441.00
19_L23_M0.6421.00
200_M204_V0.6411.00
78_N228_S0.6401.00
177_S180_I0.6401.00
41_P53_K0.6321.00
140_M143_S0.6311.00
57_F60_Y0.6301.00
24_A27_I0.6291.00
201_A205_A0.6271.00
251_A254_A0.6271.00
267_M270_K0.6271.00
100_A104_F0.6261.00
113_L161_Y0.6241.00
141_I144_H0.6241.00
97_T116_F0.6221.00
162_L200_M0.6211.00
108_G112_A0.6181.00
44_S53_K0.6171.00
60_Y252_A0.6161.00
105_R110_K0.6161.00
67_K74_Q0.6161.00
133_V136_Q0.6151.00
265_F269_Q0.6071.00
63_L249_T0.6061.00
116_F157_P0.6021.00
155_L211_G0.6001.00
79_S213_L0.6001.00
232_P257_I0.5971.00
107_K111_Y0.5961.00
125_F221_T0.5931.00
106_F112_A0.5911.00
217_V220_S0.5911.00
98_A164_K0.5901.00
120_Q157_P0.5891.00
134_L141_I0.5871.00
83_S213_L0.5871.00
155_L208_G0.5871.00
268_L271_N0.5821.00
83_S212_P0.5821.00
124_Q128_L0.5821.00
38_S252_A0.5821.00
28_V32_L0.5811.00
217_V221_T0.5781.00
188_I192_I0.5771.00
262_A266_I0.5771.00
63_L253_G0.5751.00
40_N54_H0.5741.00
90_S152_I0.5731.00
131_L134_L0.5721.00
219_S233_V0.5691.00
248_T251_A0.5661.00
190_F193_I0.5661.00
82_I144_H0.5661.00
120_Q158_M0.5651.00
38_S255_L0.5631.00
247_Y251_A0.5621.00
71_Q234_G0.5621.00
110_K114_T0.5611.00
210_T214_G0.5601.00
52_P55_P0.5601.00
114_T118_L0.5591.00
112_A116_F0.5561.00
82_I86_T0.5551.00
212_P215_D0.5551.00
41_P45_L0.5551.00
266_I269_Q0.5551.00
105_R172_M0.5531.00
54_H58_D0.5521.00
211_G214_G0.5521.00
202_A205_A0.5501.00
104_F185_S0.5491.00
184_S190_F0.5491.00
86_T152_I0.5491.00
91_L95_T0.5481.00
17_Y20_L0.5481.00
119_L157_P0.5481.00
25_V29_Y0.5471.00
205_A208_G0.5461.00
40_N53_K0.5421.00
37_A42_G0.5401.00
93_C156_I0.5401.00
99_Y193_I0.5401.00
66_G73_V0.5381.00
247_Y250_F0.5381.00
151_Y215_D0.5371.00
67_K73_V0.5351.00
263_V266_I0.5351.00
97_T100_A0.5331.00
91_L96_F0.5281.00
13_L16_S0.5281.00
87_M212_P0.5261.00
170_I175_D0.5261.00
233_V236_F0.5251.00
176_E179_K0.5251.00
39_F57_F0.5211.00
94_V156_I0.5151.00
41_P56_T0.5151.00
204_V208_G0.5141.00
42_G52_P0.5141.00
61_K66_G0.5131.00
151_Y219_S0.5121.00
245_A249_T0.5121.00
78_N230_T0.5081.00
249_T252_A0.5081.00
95_T194_L0.5041.00
264_I268_L0.5031.00
35_A39_F0.5031.00
113_L168_D0.5021.00
72_Y234_G0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3rlfG 1 0.9541 100 0.251 Contact Map
4tquN 1 0.9399 100 0.265 Contact Map
2onkC 2 0.8551 100 0.31 Contact Map
4tquM 1 0.9046 100 0.328 Contact Map
3d31C 2 0.8375 100 0.332 Contact Map
3rlfF 1 0.9258 100 0.388 Contact Map
4ymuD 2 0.7527 99.9 0.483 Contact Map
3tuiA 2 0.735 99.9 0.524 Contact Map
2a65A 2 0.8375 10.9 0.947 Contact Map
4xp4A 1 0.8693 8.1 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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