CYCB - BACSU - GREMLIN Contacts

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CYCB - Cyclodextrin-binding protein

UniProt:	O07009	Sequences: MKMAKKCSVFMLCAAVSLSLAACGPKESSSAKSSSKGSELVVWEDKEKSNGIKDAVAAFEKEHDVKVKVVEKPYAKQIEDLRMDGPAGTGPDVLTMPGDQIGTAVTEGLLKELHVKKDVQSLYTDASIQSQMVDQKLYGLPKAVETTVLFYNKDLITEKELPKTLEEWYDYSKKTADGSKFGFLALFDQIYYAESVMSGYGGYIFGKAKDGSYNPSDIGINNEGAVKGAALIQKFYKDGLFPAGIIGEQGINVLESLFTEGKAAAIISGPWNVEAFSNAGINYGITKLPKLENGKNMSSFIGVKSYNVSAFSKNEELAQELAVFLANEKNSKTRYEETKEVPAVKSLANDPAIMKSEAARAVTEQSRFSEPTPNIPEMNEIWTPADSALQTVATGKADPKQALDQAAETAKGQIKAKHSGK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	421 (393)
Sequences:	30473 (24309)
Seq/√Len:	1226.2

ECOLI - MALE UGPB YCJN YDCS YNJB POTF POTD THIB
BACSU - CYCB MDXE ARAN YTCQ YESO YURO LIPO MSME
HALSA - Q9HHQ8 Q9HP00 Q9HR87 Q9HNZ3 Q9HMT5 Q9HR04
SULSO - Q97YY1 Q97ZC3 Q97UZ1 Q97VC2 Q97UF5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
39_E	68_K	3.585	1.00
398_D	401_Q	3.133	1.00
111_K	315_E	3.109	1.00
226_V	400_K	2.989	1.00
154_D	282_N	2.989	1.00
153_K	284_G	2.946	1.00
112_E	136_K	2.921	1.00
41_V	68_K	2.853	1.00
169_Y	234_K	2.783	1.00
39_E	66_K	2.748	1.00
233_Q	237_K	2.690	1.00
234_K	238_D	2.451	1.00
173_K	238_D	2.430	1.00
164_T	167_E	2.371	1.00
153_K	157_T	2.350	1.00
230_A	234_K	2.299	1.00
65_V	317_L	2.272	1.00
76_K	79_E	2.264	1.00
63_H	320_E	2.262	1.00
53_K	57_A	2.247	1.00
151_Y	284_G	2.217	1.00
223_E	227_K	2.197	1.00
60_E	66_K	2.190	1.00
404_D	408_E	2.151	1.00
58_A	61_K	2.142	1.00
170_D	174_K	2.138	1.00
114_H	136_K	2.133	1.00
407_A	411_K	2.126	1.00
400_K	404_D	2.095	1.00
132_M	137_L	2.078	1.00
230_A	399_P	2.056	1.00
41_V	70_V	2.047	1.00
327_N	330_N	2.033	1.00
161_L	171_Y	2.025	1.00
397_A	405_Q	2.022	1.00
320_E	323_V	2.012	1.00
58_A	324_F	2.001	1.00
391_T	396_K	2.000	1.00
54_D	57_A	1.961	1.00
314_N	317_L	1.925	1.00
125_D	129_Q	1.913	1.00
156_I	265_A	1.904	1.00
37_G	66_K	1.891	1.00
58_A	62_E	1.857	1.00
250_G	253_V	1.856	1.00
60_E	63_H	1.853	1.00
391_T	397_A	1.845	1.00
227_K	230_A	1.841	1.00
129_Q	132_M	1.838	1.00
154_D	158_E	1.835	1.00
173_K	177_D	1.835	1.00
59_F	320_E	1.829	1.00
167_E	170_D	1.820	1.00
116_K	319_Q	1.799	1.00
57_A	61_K	1.786	1.00
110_L	307_N	1.785	1.00
170_D	173_K	1.758	1.00
58_A	333_T	1.754	1.00
408_E	412_G	1.752	1.00
332_K	336_E	1.751	1.00
221_N	404_D	1.721	1.00
384_P	409_T	1.716	1.00
226_V	230_A	1.671	1.00
360_R	364_E	1.661	1.00
405_Q	409_T	1.660	1.00
383_T	387_S	1.652	1.00
92_D	314_N	1.645	1.00
122_L	346_S	1.633	1.00
56_V	60_E	1.630	1.00
38_S	317_L	1.609	1.00
169_Y	173_K	1.609	1.00
401_Q	405_Q	1.597	1.00
163_K	167_E	1.588	1.00
166_E	169_Y	1.587	1.00
139_G	305_S	1.582	1.00
206_G	217_D	1.581	1.00
184_L	263_A	1.580	1.00
169_Y	238_D	1.573	1.00
316_E	320_E	1.572	1.00
230_A	400_K	1.565	1.00
73_P	76_K	1.562	1.00
131_Q	305_S	1.558	1.00
392_V	402_A	1.557	1.00
155_L	264_A	1.552	1.00
404_D	407_A	1.537	1.00
328_E	332_K	1.536	1.00
43_W	84_D	1.531	1.00
56_V	321_L	1.527	1.00
59_F	63_H	1.512	1.00
94_L	309_S	1.510	1.00
57_A	60_E	1.508	1.00
15_A	18_L	1.495	1.00
80_D	84_D	1.487	1.00
401_Q	404_D	1.484	1.00
257_L	262_K	1.468	1.00
111_K	310_A	1.467	1.00
149_L	286_T	1.457	1.00
175_T	264_A	1.455	1.00
388_A	405_Q	1.455	1.00
169_Y	235_F	1.450	1.00
173_K	240_L	1.450	1.00
330_N	333_T	1.449	1.00
16_V	19_S	1.448	1.00
153_K	282_N	1.447	1.00
233_Q	392_V	1.446	1.00
231_L	234_K	1.430	1.00
405_Q	408_E	1.420	1.00
151_Y	286_T	1.417	1.00
85_G	90_G	1.416	1.00
226_V	399_P	1.400	1.00
388_A	397_A	1.395	1.00
54_D	58_A	1.391	1.00
333_T	337_E	1.385	1.00
308_V	322_A	1.384	1.00
224_G	227_K	1.378	1.00
388_A	391_T	1.378	1.00
221_N	407_A	1.361	1.00
206_G	210_D	1.352	1.00
166_E	170_D	1.346	1.00
361_A	364_E	1.337	1.00
155_L	175_T	1.325	1.00
169_Y	231_L	1.319	1.00
397_A	402_A	1.312	1.00
392_V	399_P	1.308	1.00
44_E	69_V	1.302	1.00
59_F	324_F	1.299	1.00
364_E	367_R	1.291	1.00
317_L	320_E	1.290	1.00
38_S	314_N	1.276	1.00
312_S	315_E	1.271	1.00
231_L	235_F	1.270	1.00
112_E	115_V	1.263	1.00
207_K	210_D	1.263	1.00
13_C	17_S	1.242	1.00
258_F	283_Y	1.240	1.00
59_F	321_L	1.240	1.00
256_S	260_E	1.235	1.00
408_E	411_K	1.227	1.00
37_G	64_D	1.225	1.00
234_K	237_K	1.224	1.00
105_V	138_Y	1.223	1.00
50_N	53_K	1.221	1.00
161_L	174_K	1.217	1.00
93_V	318_A	1.215	1.00
56_V	69_V	1.211	1.00
319_Q	323_V	1.196	1.00
59_F	65_V	1.193	1.00
397_A	401_Q	1.190	1.00
172_S	265_A	1.189	1.00
312_S	318_A	1.187	1.00
227_K	231_L	1.182	1.00
152_N	155_L	1.181	1.00
96_M	307_N	1.179	1.00
120_Q	128_I	1.175	1.00
409_T	412_G	1.164	1.00
148_V	285_I	1.159	1.00
384_P	387_S	1.158	1.00
149_L	265_A	1.157	1.00
171_Y	174_K	1.148	1.00
351_P	355_K	1.137	1.00
203_Y	207_K	1.135	1.00
131_Q	137_L	1.133	1.00
154_D	281_I	1.132	1.00
166_E	292_E	1.129	1.00
115_V	118_D	1.124	1.00
363_T	367_R	1.121	1.00
80_D	83_M	1.121	1.00
50_N	54_D	1.119	1.00
388_A	406_A	1.119	1.00
324_F	330_N	1.116	1.00
159_K	175_T	1.111	1.00
172_S	240_L	1.108	1.00
156_I	171_Y	1.107	1.00
391_T	405_Q	1.106	1.00
128_I	132_M	1.105	1.00
203_Y	206_G	1.102	1.00
119_V	122_L	1.101	1.00
315_E	319_Q	1.095	1.00
65_V	320_E	1.095	1.00
176_A	182_G	1.094	1.00
346_S	349_N	1.090	1.00
387_S	409_T	1.088	1.00
108_G	310_A	1.087	1.00
62_E	327_N	1.087	1.00
230_A	233_Q	1.071	1.00
275_A	278_N	1.070	1.00
92_D	312_S	1.069	1.00
223_E	226_V	1.064	1.00
88_G	311_F	1.060	1.00
152_N	281_I	1.059	1.00
168_W	172_S	1.057	1.00
42_V	306_Y	1.053	1.00
155_L	180_K	1.050	1.00
176_A	240_L	1.050	1.00
257_L	263_A	1.049	1.00
180_K	262_K	1.046	1.00
321_L	325_L	1.044	1.00
168_W	265_A	1.037	1.00
171_Y	265_A	1.024	1.00
23_C	26_K	1.023	1.00
310_A	315_E	1.021	1.00
333_T	336_E	1.019	1.00
328_E	346_S	1.016	1.00
253_V	256_S	1.015	1.00
226_V	403_L	1.013	1.00
308_V	318_A	1.013	1.00
93_V	322_A	1.012	1.00
51_G	54_D	1.010	1.00
329_K	332_K	1.007	1.00
168_W	183_F	1.007	1.00
309_S	312_S	1.000	1.00
381_I	410_A	0.999	1.00
155_L	158_E	0.996	1.00
233_Q	399_P	0.994	1.00
59_F	317_L	0.990	1.00
356_S	360_R	0.990	1.00
156_I	161_L	0.990	1.00
174_K	177_D	0.989	1.00
105_V	133_V	0.984	1.00
388_A	409_T	0.984	1.00
58_A	329_K	0.983	1.00
387_S	391_T	0.981	1.00
218_I	411_K	0.980	1.00
12_L	16_V	0.980	1.00
344_V	347_L	0.979	1.00
17_S	20_L	0.973	1.00
54_D	333_T	0.973	1.00
94_L	307_N	0.972	1.00
23_C	27_E	0.970	1.00
78_I	100_Q	0.965	1.00
16_V	20_L	0.963	1.00
85_G	109_L	0.962	1.00
155_L	159_K	0.961	1.00
268_S	272_N	0.961	1.00
93_V	321_L	0.960	1.00
81_L	94_L	0.958	1.00
116_K	316_E	0.958	1.00
150_F	268_S	0.955	1.00
308_V	319_Q	0.954	1.00
364_E	368_F	0.950	1.00
154_D	157_T	0.947	1.00
384_P	388_A	0.945	1.00
175_T	178_G	0.942	1.00
54_D	337_E	0.939	1.00
40_L	321_L	0.934	1.00
380_E	383_T	0.933	1.00
55_A	58_A	0.931	1.00
12_L	18_L	0.926	1.00
12_L	15_A	0.926	1.00
321_L	324_F	0.925	1.00
229_A	392_V	0.923	1.00
200_Y	227_K	0.919	1.00
318_A	322_A	0.914	1.00
357_E	360_R	0.913	1.00
124_T	345_K	0.913	1.00
67_V	321_L	0.908	1.00
125_D	128_I	0.906	1.00
64_D	320_E	0.905	1.00
142_K	306_Y	0.903	1.00
90_G	309_S	0.902	1.00
351_P	354_M	0.901	1.00
38_S	64_D	0.896	1.00
383_T	386_D	0.895	1.00
111_K	312_S	0.886	1.00
163_K	290_K	0.885	1.00
157_T	282_N	0.884	1.00
8_S	19_S	0.881	1.00
316_E	319_Q	0.878	1.00
122_L	344_V	0.878	1.00
15_A	19_S	0.875	1.00
256_S	259_T	0.874	1.00
126_A	129_Q	0.870	1.00
403_L	407_A	0.870	1.00
329_K	333_T	0.868	1.00
161_L	175_T	0.865	1.00
19_S	22_A	0.864	1.00
11_M	15_A	0.861	1.00
56_V	67_V	0.860	1.00
388_A	402_A	0.856	1.00
162_P	167_E	0.846	1.00
83_M	87_A	0.844	1.00
8_S	15_A	0.842	1.00
84_D	89_T	0.840	1.00
332_K	350_D	0.839	1.00
398_D	402_A	0.835	1.00
128_I	137_L	0.834	1.00
55_A	330_N	0.831	1.00
158_E	180_K	0.830	1.00
40_L	317_L	0.828	1.00
308_V	312_S	0.820	1.00
152_N	282_N	0.819	1.00
229_A	403_L	0.818	1.00
139_G	307_N	0.818	1.00
13_C	19_S	0.815	1.00
218_I	407_A	0.815	1.00
235_F	240_L	0.815	1.00
20_L	23_C	0.815	1.00
169_Y	240_L	0.813	1.00
58_A	330_N	0.813	1.00
43_W	72_K	0.812	1.00
197_M	225_A	0.811	1.00
402_A	406_A	0.809	1.00
114_H	118_D	0.809	1.00
210_D	217_D	0.809	1.00
72_K	80_D	0.805	1.00
62_E	324_F	0.804	1.00
181_F	243_A	0.804	1.00
11_M	17_S	0.801	1.00
239_G	243_A	0.798	1.00
384_P	406_A	0.798	1.00
103_T	107_E	0.797	1.00
132_M	135_Q	0.795	1.00
159_K	174_K	0.793	1.00
233_Q	236_Y	0.793	1.00
377_E	380_E	0.792	1.00
114_H	137_L	0.792	1.00
94_L	110_L	0.790	1.00
206_G	211_G	0.781	1.00
38_S	65_V	0.777	1.00
197_M	202_G	0.777	1.00
148_V	362_V	0.775	1.00
79_E	83_M	0.773	1.00
8_S	11_M	0.770	1.00
366_S	369_S	0.769	1.00
402_A	405_Q	0.768	1.00
123_Y	326_A	0.768	1.00
165_L	169_Y	0.767	1.00
193_A	197_M	0.767	1.00
14_A	18_L	0.766	1.00
169_Y	172_S	0.764	1.00
114_H	132_M	0.763	1.00
40_L	314_N	0.757	1.00
14_A	17_S	0.757	1.00
105_V	110_L	0.756	1.00
60_E	67_V	0.756	1.00
382_W	386_D	0.755	1.00
62_E	329_K	0.754	1.00
173_K	176_A	0.754	1.00
332_K	347_L	0.753	1.00
219_G	222_N	0.753	1.00
220_I	225_A	0.753	1.00
23_C	28_S	0.750	1.00
229_A	402_A	0.747	1.00
361_A	365_Q	0.746	1.00
172_S	182_G	0.743	1.00
111_K	308_V	0.742	1.00
110_L	138_Y	0.741	1.00
387_S	390_Q	0.741	1.00
252_N	255_E	0.740	1.00
385_A	406_A	0.737	1.00
156_I	175_T	0.736	1.00
60_E	64_D	0.736	1.00
159_K	178_G	0.735	1.00
13_C	16_V	0.734	1.00
11_M	18_L	0.732	1.00
171_Y	175_T	0.732	1.00
111_K	309_S	0.732	1.00
102_G	106_T	0.729	1.00
111_K	319_Q	0.729	1.00
8_S	18_L	0.726	1.00
274_E	278_N	0.725	1.00
360_R	363_T	0.724	1.00
8_S	12_L	0.724	1.00
111_K	115_V	0.721	1.00
403_L	406_A	0.719	1.00
222_N	225_A	0.718	1.00
292_E	295_K	0.718	1.00
362_V	366_S	0.717	1.00
125_D	345_K	0.715	1.00
176_A	239_G	0.714	1.00
206_G	219_G	0.714	1.00
120_Q	132_M	0.713	1.00
119_V	323_V	0.711	1.00
104_A	110_L	0.707	1.00
200_Y	231_L	0.705	1.00
123_Y	128_I	0.705	1.00
345_K	349_N	0.704	1.00
11_M	14_A	0.699	1.00
172_S	176_A	0.699	1.00
275_A	279_A	0.698	1.00
111_K	116_K	0.698	1.00
112_E	138_Y	0.696	1.00
117_K	137_L	0.696	1.00
42_V	93_V	0.696	1.00
45_D	48_K	0.696	1.00
82_R	103_T	0.693	1.00
150_F	285_I	0.693	1.00
100_Q	103_T	0.690	1.00
222_N	226_V	0.686	1.00
151_Y	156_I	0.685	1.00
9_V	13_C	0.683	1.00
9_V	16_V	0.682	1.00
347_L	350_D	0.682	1.00
43_W	91_P	0.681	1.00
165_L	231_L	0.678	1.00
7_C	18_L	0.678	1.00
227_K	291_L	0.678	1.00
217_D	411_K	0.677	1.00
12_L	19_S	0.677	1.00
242_P	245_I	0.676	1.00
202_G	225_A	0.675	1.00
111_K	311_F	0.668	1.00
252_N	256_S	0.665	1.00
77_Q	81_L	0.664	1.00
70_V	84_D	0.663	1.00
390_Q	394_T	0.661	1.00
66_K	69_V	0.660	1.00
242_P	257_L	0.657	1.00
358_A	362_V	0.656	1.00
198_S	370_E	0.654	1.00
159_K	180_K	0.653	1.00
122_L	328_E	0.650	1.00
359_A	363_T	0.649	1.00
352_A	355_K	0.647	1.00
369_S	372_T	0.646	1.00
40_L	318_A	0.645	1.00
357_E	361_A	0.645	1.00
124_T	127_S	0.645	1.00
55_A	324_F	0.645	1.00
63_H	317_L	0.644	1.00
10_F	14_A	0.642	1.00
159_K	171_Y	0.641	1.00
378_M	382_W	0.640	1.00
349_N	354_M	0.637	1.00
41_V	92_D	0.637	1.00
154_D	261_G	0.636	1.00
237_K	395_G	0.633	1.00
195_S	198_S	0.631	1.00
181_F	242_P	0.630	1.00
399_P	403_L	0.628	1.00
60_E	65_V	0.627	1.00
18_L	21_A	0.625	1.00
9_V	12_L	0.625	1.00
232_I	236_Y	0.623	1.00
152_N	261_G	0.623	1.00
124_T	348_A	0.621	1.00
115_V	136_K	0.615	1.00
79_E	82_R	0.615	1.00
306_Y	322_A	0.615	1.00
17_S	21_A	0.614	1.00
14_A	19_S	0.613	1.00
274_E	277_S	0.613	1.00
198_S	203_Y	0.612	1.00
35_S	64_D	0.611	1.00
392_V	397_A	0.609	1.00
254_L	266_I	0.609	1.00
156_I	159_K	0.608	1.00
55_A	333_T	0.608	1.00
249_Q	257_L	0.607	1.00
173_K	234_K	0.606	1.00
42_V	69_V	0.606	1.00
85_G	309_S	0.606	1.00
228_G	232_I	0.604	1.00
76_K	80_D	0.603	1.00
131_Q	139_G	0.602	1.00
163_K	168_W	0.601	1.00
224_G	228_G	0.600	1.00
176_A	181_F	0.600	1.00
70_V	80_D	0.599	1.00
38_S	42_V	0.598	1.00
113_L	322_A	0.598	1.00
52_I	55_A	0.597	1.00
320_E	324_F	0.597	1.00
78_I	103_T	0.597	1.00
149_L	267_I	0.596	1.00
22_A	25_P	0.595	1.00
101_I	139_G	0.594	1.00
220_I	410_A	0.593	1.00
323_V	327_N	0.593	1.00
222_N	407_A	0.593	1.00
112_E	137_L	0.592	1.00
184_L	254_L	0.592	1.00
46_K	49_S	0.591	1.00
194_E	198_S	0.591	1.00
257_L	260_E	0.590	1.00
377_E	381_I	0.588	1.00
93_V	306_Y	0.587	1.00
26_K	29_S	0.586	1.00
150_F	273_V	0.585	1.00
350_D	353_I	0.582	1.00
255_E	259_T	0.582	1.00
188_D	250_G	0.582	1.00
358_A	361_A	0.579	1.00
273_V	277_S	0.579	1.00
43_W	70_V	0.579	1.00
117_K	319_Q	0.579	1.00
319_Q	322_A	0.578	1.00
7_C	10_F	0.578	1.00
328_E	344_V	0.578	1.00
119_V	124_T	0.577	1.00
63_H	321_L	0.576	1.00
115_V	319_Q	0.576	1.00
163_K	171_Y	0.575	1.00
10_F	17_S	0.575	1.00
236_Y	241_F	0.574	1.00
106_T	134_D	0.574	1.00
13_C	18_L	0.573	1.00
350_D	354_M	0.573	1.00
174_K	178_G	0.572	1.00
21_A	24_G	0.572	1.00
315_E	318_A	0.571	1.00
151_Y	265_A	0.570	1.00
306_Y	325_L	0.569	1.00
391_T	402_A	0.568	1.00
399_P	402_A	0.567	1.00
172_S	235_F	0.567	1.00
391_T	395_G	0.566	1.00
277_S	283_Y	0.566	1.00
51_G	55_A	0.564	1.00
41_V	44_E	0.562	1.00
184_L	257_L	0.562	1.00
37_G	63_H	0.560	1.00
150_F	283_Y	0.560	1.00
167_E	171_Y	0.560	1.00
140_L	322_A	0.559	1.00
105_V	108_G	0.558	1.00
92_D	318_A	0.558	1.00
175_T	265_A	0.556	1.00
365_Q	368_F	0.556	1.00
379_N	383_T	0.556	1.00
345_K	348_A	0.556	1.00
78_I	82_R	0.554	1.00
203_Y	219_G	0.554	1.00
101_I	105_V	0.553	1.00
259_T	279_A	0.553	1.00
37_G	65_V	0.552	1.00
109_L	112_E	0.550	1.00
120_Q	123_Y	0.550	1.00
38_S	41_V	0.549	1.00
121_S	124_T	0.548	1.00
116_K	315_E	0.548	1.00
356_S	359_A	0.547	1.00
70_V	91_P	0.547	1.00
175_T	180_K	0.547	1.00
55_A	325_L	0.546	1.00
45_D	49_S	0.546	1.00
363_T	366_S	0.544	1.00
36_K	64_D	0.543	1.00
127_S	144_V	0.542	1.00
9_V	15_A	0.542	1.00
348_A	351_P	0.541	1.00
181_F	185_A	0.540	1.00
249_Q	253_V	0.540	1.00
19_S	23_C	0.540	1.00
25_P	28_S	0.538	1.00
114_H	319_Q	0.537	1.00
157_T	160_E	0.534	1.00
96_M	104_A	0.532	1.00
10_F	16_V	0.532	1.00
180_K	184_L	0.531	1.00
10_F	13_C	0.530	1.00
253_V	257_L	0.530	1.00
41_V	91_P	0.530	1.00
63_H	324_F	0.530	1.00
197_M	228_G	0.529	1.00
21_A	25_P	0.529	1.00
272_N	276_F	0.528	1.00
207_K	211_G	0.526	1.00
233_Q	398_D	0.525	1.00
235_F	241_F	0.524	1.00
263_A	267_I	0.524	1.00
38_S	63_H	0.523	1.00
23_C	29_S	0.523	1.00
380_E	384_P	0.521	1.00
180_K	264_A	0.521	1.00
237_K	240_L	0.521	1.00
35_S	38_S	0.520	1.00
290_K	295_K	0.520	1.00
159_K	264_A	0.520	1.00
102_G	133_V	0.520	1.00
82_R	86_P	0.519	1.00
42_V	52_I	0.519	1.00
24_G	27_E	0.518	1.00
305_S	309_S	0.515	1.00
7_C	14_A	0.515	1.00
9_V	19_S	0.514	1.00
22_A	26_K	0.513	1.00
140_L	326_A	0.511	1.00
108_G	111_K	0.510	1.00
258_F	281_I	0.510	1.00
284_G	287_K	0.510	1.00
225_A	229_A	0.507	1.00
166_E	291_L	0.507	1.00
287_K	364_E	0.505	1.00
301_I	305_S	0.504	1.00
53_K	69_V	0.504	1.00
192_Y	200_Y	0.502	1.00
78_I	97_P	0.501	1.00
20_L	24_G	0.501	1.00
153_K	281_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3uorA	1	0.8907	100	0.147	Contact Map
4r2fA	1	0.8717	100	0.148	Contact Map
4r9fA	1	0.8717	100	0.185	Contact Map
4r6kA	1	0.8884	100	0.191	Contact Map
2zyoA	1	0.9002	100	0.193	Contact Map
4mfiA	1	0.8884	100	0.195	Contact Map
2xd3A	1	0.8694	100	0.203	Contact Map
1ursA	1	0.8575	100	0.222	Contact Map
4r6hA	1	0.8884	100	0.222	Contact Map
3vxbA	1	0.8717	100	0.222	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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