GREMLIN Database
YVEG - UPF0311 protein YveG
UniProt: O07005 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 156 (148)
Sequences: 614 (497)
Seq/√Len: 40.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
52_R78_E6.4891.00
14_S151_D3.7451.00
79_T129_Y3.6561.00
10_K154_E3.6511.00
81_D129_Y3.6221.00
124_T127_E3.0481.00
12_F137_F2.5761.00
122_F132_L2.5521.00
46_T50_K2.4111.00
11_P14_S2.3991.00
24_T32_L2.3001.00
85_I122_F2.2791.00
120_P152_I2.2151.00
83_E126_S2.1290.99
45_I51_G2.0920.99
73_A89_N2.0190.99
119_V136_L2.0120.99
135_R154_E2.0040.99
83_E124_T1.9680.99
90_N121_T1.9570.99
79_T83_E1.8590.98
75_Y89_N1.8180.98
51_G77_I1.7860.98
33_R123_E1.7850.98
35_F58_A1.7650.98
102_Q107_E1.7220.97
45_I77_I1.7160.97
93_R143_R1.6360.96
95_V100_R1.6250.96
11_P48_E1.6100.96
89_N118_T1.5550.95
12_F135_R1.5160.94
102_Q113_H1.4450.93
130_Q134_D1.4340.92
74_R88_E1.4080.92
64_R70_D1.4000.91
89_N120_P1.3870.91
83_E129_Y1.3840.91
23_I84_L1.3800.91
83_E128_V1.3200.89
20_D41_R1.3020.88
89_N150_L1.2960.88
91_G118_T1.2670.87
83_E125_G1.2550.86
89_N141_A1.2460.86
72_S88_E1.2340.85
12_F49_V1.2160.84
29_S133_H1.1870.83
34_X93_R1.1610.81
124_T128_V1.1530.81
76_V84_L1.1240.79
9_L155_V1.1200.79
83_E127_E1.1180.79
43_G51_G1.1130.78
14_S149_L1.1100.78
12_F132_L1.1090.78
102_Q106_G1.1090.78
116_F141_A1.1080.78
86_Y123_E1.1070.78
45_I49_V1.0840.77
75_Y87_I1.0650.75
17_I40_I1.0620.75
122_F137_F1.0600.75
77_I122_F1.0270.73
33_R62_M1.0000.71
10_K48_E0.9950.70
9_L153_Y0.9940.70
43_G57_G0.9880.70
36_I61_Q0.9820.69
50_K80_A0.9740.68
73_A118_T0.9590.67
12_F154_E0.9340.65
130_Q133_H0.9320.65
93_R116_F0.9300.65
40_I53_I0.9260.65
72_S150_L0.9230.64
18_K41_R0.9200.64
40_I57_G0.9140.64
18_K42_S0.9080.63
102_Q105_A0.9070.63
34_X61_Q0.9040.63
118_T139_G0.9020.62
24_T34_X0.8990.62
142_E149_L0.8930.62
89_N137_F0.8870.61
73_A150_L0.8830.61
60_S118_T0.8800.61
100_R103_A0.8790.60
19_V73_A0.8760.60
25_I76_V0.8750.60
49_V85_I0.8620.59
79_T85_I0.8500.58
101_K104_A0.8450.57
25_I35_F0.8440.57
40_I75_Y0.8420.57
6_K27_E0.8400.57
101_K105_A0.8380.57
99_F114_V0.8370.57
20_D37_P0.8290.56
79_T133_H0.8230.55
67_G104_A0.8190.55
73_A87_I0.8190.55
71_L91_G0.8140.55
60_S91_G0.8080.54
54_L78_E0.8060.54
40_I89_N0.8050.54
18_K44_T0.7990.53
95_V103_A0.7860.52
76_V141_A0.7830.52
61_Q143_R0.7780.51
60_S74_R0.7680.50
94_Q134_D0.7520.49
55_P64_R0.7480.48
109_I114_V0.7440.48
124_T133_H0.7400.48
30_L123_E0.7400.48
42_S148_V0.7340.47
95_V109_I0.7330.47
58_A87_I0.7260.46
80_A85_I0.7180.46
28_T125_G0.7160.46
10_K135_R0.7130.45
37_P58_A0.7120.45
75_Y148_V0.7110.45
72_S124_T0.7060.45
48_E153_Y0.7050.45
95_V114_V0.7040.44
49_V132_L0.7040.44
89_N152_I0.6920.43
67_G113_H0.6850.43
78_E84_L0.6630.41
95_V143_R0.6630.41
41_R147_Y0.6610.41
138_I155_V0.6580.40
109_I113_H0.6570.40
105_A108_I0.6570.40
139_G150_L0.6550.40
60_S76_V0.6540.40
17_I45_I0.6510.40
40_I87_I0.6500.40
85_I131_W0.6470.39
97_K101_K0.6440.39
102_Q109_I0.6390.39
22_P106_G0.6390.39
8_V65_A0.6380.38
47_G131_W0.6370.38
44_T80_A0.6350.38
53_I60_S0.6340.38
71_L153_Y0.6310.38
27_E32_L0.6300.38
104_A144_T0.6260.37
19_V116_F0.6260.37
28_T40_I0.6250.37
60_S72_S0.6240.37
84_L125_G0.6190.37
43_G53_I0.6180.37
136_L155_V0.6140.36
68_R94_Q0.6120.36
76_V86_Y0.6070.36
82_H132_L0.6050.36
19_V67_G0.6020.35
49_V80_A0.5990.35
61_Q139_G0.5980.35
16_E147_Y0.5940.35
14_S117_R0.5920.35
20_D105_A0.5900.34
61_Q69_T0.5890.34
37_P42_S0.5850.34
93_R109_I0.5830.34
13_A19_V0.5820.34
24_T36_I0.5810.34
36_I148_V0.5790.33
61_Q148_V0.5790.33
12_F129_Y0.5760.33
44_T110_E0.5720.33
24_T72_S0.5690.33
56_G116_F0.5640.32
139_G148_V0.5630.32
35_F76_V0.5600.32
104_A134_D0.5590.32
36_I75_Y0.5580.32
45_I137_F0.5550.32
96_S114_V0.5530.31
17_I75_Y0.5520.31
120_P137_F0.5520.31
95_V99_F0.5510.31
65_A132_L0.5510.31
114_V143_R0.5500.31
37_P40_I0.5410.30
58_A74_R0.5370.30
49_V54_L0.5370.30
16_E20_D0.5340.30
45_I50_K0.5340.30
18_K147_Y0.5330.30
103_A114_V0.5300.30
93_R96_S0.5290.29
61_Q93_R0.5290.29
99_F103_A0.5230.29
15_L69_T0.5220.29
123_E127_E0.5220.29
127_E130_Q0.5190.29
61_Q73_A0.5190.29
20_D55_P0.5180.29
40_I148_V0.5170.29
13_A77_I0.5170.29
53_I146_D0.5130.28
97_K155_V0.5120.28
104_A109_I0.5120.28
111_P143_R0.5110.28
16_E44_T0.5100.28
48_E110_E0.5100.28
99_F113_H0.5080.28
27_E30_L0.5080.28
58_A86_Y0.5080.28
35_F60_S0.5070.28
20_D108_I0.5070.28
27_E46_T0.5060.28
17_I89_N0.5060.28
71_L116_F0.5060.28
72_S117_R0.5050.28
48_E107_E0.5010.27
131_W139_G0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3g7gA 3 0.9551 100 0.126 Contact Map
4puxA 4 0.9872 100 0.127 Contact Map
3c5oA 4 0.9679 100 0.141 Contact Map
3etoA 1 0.6282 4.8 0.956 Contact Map
2c5qA 3 0.6859 4 0.957 Contact Map
4tq2A 2 0.6923 3.7 0.958 Contact Map
2oo4A 1 0.5962 3.7 0.958 Contact Map
1dp7P 1 0.1859 2.9 0.96 Contact Map
1q5xA 3 0.3846 2.6 0.961 Contact Map
3oaeA 5 0.3205 2.5 0.961 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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