ASPP - BACSU - GREMLIN Contacts

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ASPP - Aspartate-proton symporter

UniProt:	O07002	Sequences: MSKQGNFQKSMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGAFSWILGGAIILLIGLVYAELGAALPRTGGIIRYPVYSHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPGLTIKGSDSPTISGWILQFALLCLFFLLNYWSVKTFAKANFIISIFKYIVPITIIIVLIFHFQPENLSVQGFAPFGFTGIQAAISTGGVMFAYLGLHPIVSVAGEVQNPKRNIPIALIICIIVSTIIYTVLQVTFIGAIPTETLKHGWPAIGREFSLPFKDIAVMLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAWARNGTLFGIFSKVNKDTGTPRASLWLSFALSIFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKDLNRPFYLKGMSIIGPLSFIFTAFIVYWSGWKTVSWLLGSQLVMFLIYLCFSKYTPKEDVSLAQQLKSAWWLIGFYIMMLIFSYIGSFGHGLGIISNPVDLILVAIGSLAIYYWAKYTGLPKAAIDYDK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	520 (423)
Sequences:	24150 (15541)
Seq/√Len:	755.6

ECOLI - PROY PUUP ANSP AROP PLAP LYSP FRLA ADIC MMUP POTE GABP YIFK GADC YBAT PHEP CYCA YGJI ARCD YCAM CADB YJEM YJEH
BACSU - ASPP YBEC YHDG YFNA GABP YBXG ROCC YTNA STET HUTM YBGF YDGF ROCE YVBW AAPA YDAO ARCD YECA YCGH GERBB GERAB YNDE GERKB
HALSA - Q9HQB3 Q9HSL5 Q9HHU7
SULSO - Q97X49 Q97WS3 Q97Z63 Q97XM0 Q97U05 Q7LXI7 Q97VA6 Q97ZB5 Q97VA8 Q97U33 Q97WD4 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
145_F	348_F	4.362	1.00
329_I	342_A	4.348	1.00
52_G	244_T	3.359	1.00
377_A	410_F	3.236	1.00
332_K	342_A	3.051	1.00
230_R	234_I	3.007	1.00
12_S	226_Q	2.999	1.00
334_N	337_T	2.855	1.00
385_A	389_N	2.830	1.00
76_I	323_N	2.780	1.00
225_V	231_N	2.709	1.00
92_S	320_W	2.677	1.00
227_N	230_R	2.666	1.00
177_L	253_T	2.618	1.00
321_A	331_S	2.548	1.00
138_F	352_I	2.526	1.00
334_N	341_R	2.514	1.00
17_I	238_I	2.478	1.00
289_W	293_L	2.477	1.00
329_I	332_K	2.449	1.00
223_G	322_R	2.436	1.00
175_I	179_F	2.435	1.00
13_L	238_I	2.392	1.00
64_E	387_R	2.392	1.00
80_V	88_G	2.248	1.00
345_W	349_A	2.211	1.00
380_P	409_S	2.186	1.00
145_F	344_L	2.139	1.00
318_Y	322_R	2.132	1.00
146_L	150_W	2.125	1.00
16_L	225_V	2.122	1.00
224_E	315_R	2.108	1.00
13_L	17_I	2.089	1.00
142_C	352_I	2.085	1.00
407_P	411_I	2.062	1.00
13_L	231_N	2.057	1.00
153_K	157_K	2.049	1.00
149_Y	341_R	2.030	1.00
53_A	57_L	2.014	1.00
324_G	328_G	1.960	1.00
83_H	385_A	1.959	1.00
138_F	355_T	1.956	1.00
80_V	85_H	1.941	1.00
431_S	435_M	1.926	1.00
96_I	347_S	1.921	1.00
61_V	380_P	1.919	1.00
137_Q	355_T	1.908	1.00
12_S	15_D	1.904	1.00
234_I	238_I	1.889	1.00
330_F	346_L	1.878	1.00
444_K	447_P	1.875	1.00
164_I	168_I	1.870	1.00
437_L	441_C	1.856	1.00
237_I	241_I	1.810	1.00
83_H	381_I	1.803	1.00
7_F	333_V	1.799	1.00
429_L	433_L	1.777	1.00
404_I	408_L	1.770	1.00
280_D	283_V	1.759	1.00
91_I	378_I	1.722	1.00
259_P	262_T	1.722	1.00
79_P	91_I	1.711	1.00
148_N	307_N	1.707	1.00
262_T	284_M	1.705	1.00
227_N	231_N	1.683	1.00
15_D	160_F	1.682	1.00
381_I	410_F	1.676	1.00
440_L	444_K	1.674	1.00
107_V	306_G	1.669	1.00
142_C	348_F	1.669	1.00
20_G	239_C	1.642	1.00
149_Y	345_W	1.639	1.00
168_I	172_T	1.636	1.00
54_I	412_F	1.625	1.00
411_I	415_F	1.621	1.00
17_I	242_V	1.613	1.00
182_Q	185_N	1.576	1.00
84_G	87_V	1.562	1.00
337_T	341_R	1.560	1.00
150_W	337_T	1.556	1.00
114_V	136_L	1.552	1.00
103_I	351_S	1.542	1.00
385_A	388_V	1.527	1.00
11_M	15_D	1.527	1.00
57_L	408_L	1.512	1.00
141_L	351_S	1.507	1.00
441_C	445_Y	1.501	1.00
241_I	245_I	1.497	1.00
93_F	435_M	1.491	1.00
167_Y	171_I	1.491	1.00
47_S	202_A	1.483	1.00
342_A	346_L	1.474	1.00
221_V	311_N	1.469	1.00
334_N	339_T	1.469	1.00
53_A	408_L	1.464	1.00
8_Q	338_G	1.463	1.00
169_V	297_D	1.454	1.00
107_V	141_L	1.449	1.00
328_G	332_K	1.446	1.00
51_G	208_V	1.446	1.00
110_V	140_L	1.437	1.00
178_I	253_T	1.434	1.00
317_V	343_S	1.428	1.00
43_S	192_A	1.417	1.00
313_T	347_S	1.412	1.00
227_N	234_I	1.410	1.00
328_G	331_S	1.410	1.00
138_F	142_C	1.405	1.00
283_V	291_A	1.405	1.00
79_P	378_I	1.404	1.00
72_T	223_G	1.399	1.00
59_G	240_I	1.398	1.00
443_S	447_P	1.393	1.00
15_D	156_A	1.390	1.00
318_Y	333_V	1.381	1.00
141_L	348_F	1.378	1.00
145_F	345_W	1.374	1.00
292_T	296_L	1.367	1.00
36_V	44_G	1.365	1.00
190_G	193_P	1.362	1.00
389_N	392_D	1.359	1.00
381_I	385_A	1.358	1.00
435_M	438_I	1.351	1.00
69_L	81_Y	1.335	1.00
245_I	249_V	1.312	1.00
110_V	299_I	1.312	1.00
430_G	434_V	1.307	1.00
314_S	344_L	1.298	1.00
61_V	406_G	1.294	1.00
280_D	284_M	1.288	1.00
332_K	341_R	1.287	1.00
174_I	249_V	1.286	1.00
83_H	87_V	1.283	1.00
228_P	233_P	1.281	1.00
7_F	318_Y	1.281	1.00
106_E	305_N	1.275	1.00
11_M	156_A	1.270	1.00
401_G	405_I	1.267	1.00
13_L	234_I	1.266	1.00
24_I	243_S	1.266	1.00
60_L	237_I	1.263	1.00
427_W	430_G	1.262	1.00
384_A	407_P	1.261	1.00
181_F	185_N	1.252	1.00
390_A	393_L	1.252	1.00
231_N	234_I	1.251	1.00
59_G	236_L	1.247	1.00
188_V	191_F	1.247	1.00
317_V	326_L	1.234	1.00
184_E	187_S	1.233	1.00
31_F	109_A	1.232	1.00
58_I	380_P	1.231	1.00
144_F	306_G	1.228	1.00
173_I	177_L	1.221	1.00
77_R	81_Y	1.220	1.00
391_K	395_R	1.219	1.00
82_S	382_S	1.207	1.00
426_S	429_L	1.206	1.00
11_M	16_L	1.203	1.00
438_I	441_C	1.203	1.00
391_K	394_N	1.197	1.00
276_L	280_D	1.190	1.00
132_S	135_I	1.189	1.00
421_G	425_V	1.188	1.00
430_G	433_L	1.184	1.00
377_A	414_A	1.176	1.00
147_L	158_A	1.173	1.00
198_G	202_A	1.172	1.00
14_F	18_L	1.170	1.00
181_F	256_G	1.166	1.00
410_F	414_A	1.161	1.00
45_A	252_V	1.154	1.00
438_I	442_F	1.149	1.00
342_A	345_W	1.142	1.00
404_I	407_P	1.141	1.00
441_C	444_K	1.139	1.00
16_L	235_A	1.132	1.00
177_L	257_A	1.128	1.00
198_G	201_A	1.127	1.00
68_A	395_R	1.121	1.00
415_F	419_W	1.121	1.00
172_T	176_V	1.116	1.00
19_I	221_V	1.116	1.00
37_A	44_G	1.114	1.00
96_I	317_V	1.111	1.00
134_W	138_F	1.111	1.00
433_L	437_L	1.110	1.00
402_M	406_G	1.107	1.00
226_Q	231_N	1.101	1.00
76_I	319_A	1.099	1.00
181_F	184_E	1.098	1.00
431_S	438_I	1.096	1.00
392_D	395_R	1.091	1.00
122_T	132_S	1.087	1.00
260_T	263_L	1.086	1.00
436_F	440_L	1.084	1.00
199_I	202_A	1.079	1.00
158_A	162_I	1.079	1.00
71_R	77_R	1.078	1.00
79_P	87_V	1.077	1.00
135_I	139_A	1.073	1.00
421_G	424_T	1.073	1.00
403_S	407_P	1.071	1.00
390_A	395_R	1.069	1.00
21_M	243_S	1.067	1.00
428_L	432_Q	1.063	1.00
21_M	242_V	1.061	1.00
199_I	204_S	1.058	1.00
349_A	353_F	1.057	1.00
20_G	218_I	1.056	1.00
389_N	393_L	1.051	1.00
139_A	143_L	1.051	1.00
322_R	331_S	1.047	1.00
171_I	175_I	1.047	1.00
10_S	226_Q	1.044	1.00
111_R	136_L	1.042	1.00
62_Y	75_I	1.041	1.00
159_N	307_N	1.040	1.00
442_F	446_T	1.038	1.00
188_V	192_A	1.030	1.00
49_I	248_T	1.030	1.00
428_L	431_S	1.030	1.00
383_S	406_G	1.029	1.00
43_S	191_F	1.029	1.00
333_V	338_G	1.028	1.00
195_G	198_G	1.025	1.00
439_Y	442_F	1.023	1.00
66_G	78_Y	1.021	1.00
89_Y	93_F	1.019	1.00
86_L	442_F	1.018	1.00
283_V	288_G	1.016	1.00
43_S	199_I	1.014	1.00
157_K	161_I	1.012	1.00
145_F	149_Y	1.009	1.00
188_V	193_P	1.007	1.00
213_L	372_L	0.990	1.00
426_S	430_G	0.989	1.00
152_V	311_N	0.989	1.00
426_S	439_Y	0.988	1.00
105_I	365_V	0.984	1.00
286_G	290_L	0.975	1.00
173_I	282_A	0.970	1.00
162_I	304_G	0.970	1.00
377_A	413_T	0.970	1.00
388_V	403_S	0.970	1.00
414_A	418_Y	0.969	1.00
52_G	212_Y	0.962	1.00
183_P	187_S	0.956	1.00
142_C	146_L	0.954	1.00
377_A	381_I	0.951	1.00
40_A	43_S	0.950	1.00
114_V	299_I	0.949	1.00
401_G	404_I	0.949	1.00
81_Y	390_A	0.945	1.00
429_L	435_M	0.945	1.00
189_Q	192_A	0.945	1.00
149_Y	339_T	0.939	1.00
174_I	178_I	0.937	1.00
332_K	335_K	0.935	1.00
180_H	183_P	0.935	1.00
68_A	393_L	0.934	1.00
196_F	199_I	0.932	1.00
238_I	242_V	0.929	1.00
143_L	303_G	0.928	1.00
71_R	81_Y	0.926	1.00
111_R	137_Q	0.925	1.00
259_P	284_M	0.924	1.00
244_T	248_T	0.917	1.00
287_L	290_L	0.916	1.00
435_M	439_Y	0.916	1.00
201_A	204_S	0.916	1.00
434_V	438_I	0.911	1.00
73_G	77_R	0.910	1.00
200_Q	204_S	0.908	1.00
18_L	160_F	0.903	1.00
174_I	253_T	0.902	1.00
418_Y	422_W	0.902	1.00
288_G	292_T	0.902	1.00
67_A	396_P	0.901	1.00
200_Q	415_F	0.901	1.00
64_E	67_A	0.900	1.00
393_L	396_P	0.896	1.00
216_H	220_S	0.895	1.00
196_F	200_Q	0.894	1.00
167_Y	246_I	0.885	1.00
222_A	232_I	0.885	1.00
25_F	28_A	0.881	1.00
428_L	433_L	0.881	1.00
439_Y	443_S	0.868	1.00
428_L	435_M	0.866	1.00
15_D	157_K	0.866	1.00
131_I	135_I	0.857	1.00
57_L	405_I	0.857	1.00
10_S	153_K	0.855	1.00
13_L	235_A	0.852	1.00
310_M	348_F	0.850	1.00
182_Q	186_L	0.849	1.00
149_Y	334_N	0.847	1.00
367_V	371_A	0.842	1.00
440_L	443_S	0.842	1.00
341_R	345_W	0.840	1.00
144_F	307_N	0.835	1.00
93_F	326_L	0.834	1.00
330_F	342_A	0.833	1.00
380_P	410_F	0.833	1.00
146_L	149_Y	0.830	1.00
257_A	281_I	0.829	1.00
348_F	352_I	0.829	1.00
80_V	323_N	0.829	1.00
14_F	160_F	0.828	1.00
428_L	442_F	0.827	1.00
413_T	416_I	0.826	1.00
114_V	118_F	0.826	1.00
79_P	382_S	0.825	1.00
384_A	406_G	0.823	1.00
178_I	249_V	0.822	1.00
58_I	413_T	0.821	1.00
105_I	210_F	0.820	1.00
86_L	90_L	0.816	1.00
110_V	302_P	0.813	1.00
118_F	121_L	0.813	1.00
56_L	60_L	0.811	1.00
180_H	184_E	0.807	1.00
49_I	53_A	0.804	1.00
141_L	355_T	0.804	1.00
233_P	236_L	0.803	1.00
68_A	396_P	0.802	1.00
402_M	405_I	0.802	1.00
192_A	196_F	0.797	1.00
409_S	413_T	0.797	1.00
252_V	256_G	0.796	1.00
217_P	312_T	0.795	1.00
426_S	435_M	0.792	1.00
7_F	315_R	0.791	1.00
442_F	445_Y	0.789	1.00
213_L	376_Y	0.786	1.00
157_K	160_F	0.783	1.00
25_F	166_K	0.781	1.00
110_V	303_G	0.781	1.00
199_I	203_I	0.780	1.00
326_L	330_F	0.779	1.00
136_L	139_A	0.778	1.00
131_I	134_W	0.775	1.00
144_F	310_M	0.772	1.00
87_V	378_I	0.770	1.00
440_L	447_P	0.769	1.00
434_V	437_L	0.768	1.00
166_K	301_S	0.767	1.00
263_L	266_G	0.762	1.00
73_G	76_I	0.761	1.00
7_F	224_E	0.761	1.00
370_V	428_L	0.755	1.00
415_F	418_Y	0.754	1.00
262_T	265_H	0.751	1.00
56_L	237_I	0.745	1.00
389_N	394_N	0.743	1.00
17_I	235_A	0.742	1.00
108_T	364_L	0.740	1.00
390_A	394_N	0.738	1.00
266_G	280_D	0.738	1.00
429_L	432_Q	0.737	1.00
384_A	388_V	0.736	1.00
29_W	250_L	0.734	1.00
46_F	50_L	0.734	1.00
192_A	199_I	0.733	1.00
384_A	403_S	0.733	1.00
442_F	447_P	0.732	1.00
349_A	352_I	0.732	1.00
57_L	61_V	0.732	1.00
111_R	133_G	0.730	1.00
439_Y	444_K	0.730	1.00
65_L	383_S	0.729	1.00
68_A	391_K	0.726	1.00
335_K	341_R	0.723	1.00
436_F	444_K	0.722	1.00
427_W	431_S	0.719	1.00
432_Q	436_F	0.717	1.00
39_K	42_P	0.717	1.00
227_N	233_P	0.716	1.00
317_V	346_L	0.716	1.00
55_I	215_L	0.715	1.00
98_A	372_L	0.715	1.00
10_S	152_V	0.713	1.00
65_L	78_Y	0.711	1.00
389_N	395_R	0.710	1.00
310_M	314_S	0.709	1.00
426_S	433_L	0.708	1.00
420_S	424_T	0.705	1.00
14_F	157_K	0.704	1.00
84_G	443_S	0.701	1.00
134_W	355_T	0.700	1.00
438_I	444_K	0.698	1.00
100_T	350_L	0.698	1.00
156_A	160_F	0.695	1.00
181_F	186_L	0.695	1.00
111_R	114_V	0.690	1.00
409_S	412_F	0.688	1.00
383_S	387_R	0.685	1.00
102_L	368_C	0.685	1.00
46_F	49_I	0.684	1.00
400_K	404_I	0.684	1.00
314_S	343_S	0.682	1.00
104_S	354_W	0.682	1.00
138_F	356_L	0.681	1.00
429_L	444_K	0.680	1.00
95_T	99_Y	0.679	1.00
59_G	215_L	0.679	1.00
431_S	434_V	0.678	1.00
417_V	420_S	0.676	1.00
45_A	248_T	0.676	1.00
289_W	292_T	0.675	1.00
219_V	236_L	0.674	1.00
148_N	344_L	0.673	1.00
186_L	255_I	0.673	1.00
23_A	308_I	0.672	1.00
149_Y	337_T	0.670	1.00
140_L	306_G	0.668	1.00
116_Y	295_I	0.667	1.00
72_T	318_Y	0.667	1.00
54_I	57_L	0.667	1.00
104_S	364_L	0.664	1.00
21_M	163_S	0.663	1.00
86_L	436_F	0.663	1.00
48_W	211_A	0.663	1.00
82_S	385_A	0.662	1.00
382_S	386_L	0.662	1.00
60_L	405_I	0.658	1.00
115_A	119_P	0.658	1.00
371_A	375_S	0.657	1.00
45_A	255_I	0.654	1.00
433_L	436_F	0.653	1.00
242_V	246_I	0.653	1.00
150_W	154_T	0.652	1.00
435_M	443_S	0.651	1.00
102_L	105_I	0.651	1.00
435_M	442_F	0.648	1.00
335_K	338_G	0.648	1.00
25_F	246_I	0.645	1.00
156_A	307_N	0.645	1.00
388_V	391_K	0.644	1.00
419_W	423_K	0.643	1.00
329_I	346_L	0.643	1.00
438_I	443_S	0.642	1.00
174_I	250_L	0.642	1.00
238_I	241_I	0.639	1.00
76_I	80_V	0.638	1.00
20_G	24_I	0.638	1.00
148_N	311_N	0.633	1.00
426_S	431_S	0.632	1.00
82_S	386_L	0.632	1.00
242_V	245_I	0.631	1.00
334_N	338_G	0.630	1.00
21_M	24_I	0.629	1.00
182_Q	187_S	0.629	1.00
401_G	406_G	0.627	1.00
17_I	20_G	0.627	1.00
57_L	409_S	0.627	1.00
46_F	199_I	0.625	1.00
194_F	197_T	0.623	1.00
321_A	330_F	0.623	1.00
35_N	362_N	0.622	1.00
24_I	239_C	0.621	1.00
121_L	132_S	0.621	1.00
223_G	318_Y	0.621	1.00
33_V	251_Q	0.620	1.00
430_G	437_L	0.619	1.00
395_R	398_Y	0.619	1.00
189_Q	193_P	0.619	1.00
397_F	400_K	0.618	1.00
117_W	296_L	0.617	1.00
370_V	417_V	0.617	1.00
330_F	343_S	0.616	1.00
436_F	439_Y	0.614	1.00
101_S	367_V	0.611	1.00
22_G	163_S	0.610	1.00
114_V	140_L	0.610	1.00
76_I	92_S	0.609	1.00
441_C	446_T	0.608	1.00
277_P	281_I	0.606	1.00
99_Y	309_F	0.606	1.00
249_V	253_T	0.606	1.00
154_T	157_K	0.605	1.00
403_S	406_G	0.604	1.00
426_S	440_L	0.603	1.00
434_V	442_F	0.603	1.00
62_Y	379_A	0.601	1.00
315_R	318_Y	0.600	1.00
232_I	236_L	0.600	1.00
44_G	251_Q	0.600	1.00
42_P	255_I	0.598	1.00
32_A	365_V	0.597	1.00
422_W	425_V	0.596	1.00
154_T	158_A	0.596	1.00
25_F	30_L	0.596	1.00
429_L	438_I	0.596	1.00
427_W	444_K	0.596	1.00
61_V	399_L	0.595	1.00
113_Y	298_A	0.593	1.00
426_S	438_I	0.591	1.00
142_C	145_F	0.591	1.00
66_G	219_V	0.590	1.00
253_T	256_G	0.589	1.00
373_I	413_T	0.589	1.00
51_G	209_M	0.588	1.00
386_L	390_A	0.588	1.00
439_Y	445_Y	0.587	1.00
35_N	38_S	0.587	1.00
10_S	14_F	0.585	1.00
94_V	375_S	0.584	1.00
427_W	439_Y	0.583	1.00
26_G	30_L	0.582	1.00
152_V	221_V	0.581	1.00
220_S	312_T	0.581	1.00
399_L	405_I	0.580	1.00
417_V	425_V	0.579	1.00
61_V	409_S	0.579	1.00
149_Y	344_L	0.578	1.00
399_L	402_M	0.577	1.00
151_S	154_T	0.576	1.00
435_M	444_K	0.576	1.00
276_L	279_K	0.575	1.00
144_F	303_G	0.573	1.00
277_P	282_A	0.573	1.00
165_F	297_D	0.573	1.00
313_T	317_V	0.573	1.00
353_F	356_L	0.572	1.00
418_Y	421_G	0.572	1.00
140_L	303_G	0.571	1.00
438_I	447_P	0.571	1.00
14_F	17_I	0.570	1.00
104_S	351_S	0.569	1.00
75_I	216_H	0.568	1.00
213_L	368_C	0.567	1.00
250_L	254_F	0.567	1.00
75_I	220_S	0.564	1.00
141_L	352_I	0.563	1.00
66_G	232_I	0.563	1.00
340_P	343_S	0.563	1.00
437_L	440_L	0.562	1.00
428_L	438_I	0.562	1.00
140_L	144_F	0.562	1.00
84_G	88_G	0.560	1.00
406_G	410_F	0.560	1.00
145_F	310_M	0.558	1.00
76_I	88_G	0.557	1.00
160_F	164_I	0.556	1.00
213_L	216_H	0.556	1.00
435_M	440_L	0.555	1.00
155_F	311_N	0.555	1.00
433_L	442_F	0.554	1.00
51_G	54_I	0.554	1.00
293_L	297_D	0.552	1.00
362_N	365_V	0.552	1.00
411_I	414_A	0.551	1.00
420_S	425_V	0.550	1.00
29_W	32_A	0.549	1.00
176_V	287_L	0.547	1.00
201_A	207_G	0.547	1.00
387_R	402_M	0.547	1.00
198_G	204_S	0.546	1.00
116_Y	119_P	0.545	1.00
427_W	435_M	0.544	1.00
216_H	376_Y	0.544	1.00
426_S	446_T	0.543	1.00
430_G	435_M	0.543	1.00
52_G	57_L	0.542	1.00
115_A	133_G	0.541	1.00
416_I	420_S	0.541	1.00
142_C	345_W	0.540	1.00
296_L	300_L	0.540	1.00
360_S	363_A	0.540	1.00
187_S	190_G	0.539	1.00
36_V	40_A	0.537	1.00
106_E	302_P	0.536	1.00
183_P	188_V	0.536	1.00
23_A	309_F	0.535	1.00
387_R	391_K	0.534	1.00
182_Q	188_V	0.533	1.00
100_T	347_S	0.532	1.00
16_L	221_V	0.531	1.00
301_S	304_G	0.531	1.00
65_L	82_S	0.531	1.00
310_M	344_L	0.530	1.00
83_H	382_S	0.530	1.00
361_W	365_V	0.530	1.00
412_F	416_I	0.530	1.00
429_L	439_Y	0.530	1.00
35_N	39_K	0.529	1.00
165_F	169_V	0.528	1.00
315_R	340_P	0.527	1.00
282_A	286_G	0.527	1.00
250_L	278_F	0.527	1.00
39_K	201_A	0.526	1.00
101_S	368_C	0.526	1.00
63_A	236_L	0.525	1.00
139_A	142_C	0.525	1.00
258_I	281_I	0.524	1.00
433_L	446_T	0.524	1.00
439_Y	447_P	0.523	1.00
98_A	371_A	0.522	1.00
102_L	106_E	0.520	1.00
91_I	375_S	0.519	1.00
346_L	350_L	0.517	1.00
143_L	147_L	0.517	1.00
427_W	433_L	0.517	1.00
229_K	394_N	0.515	1.00
431_S	444_K	0.515	1.00
117_W	295_I	0.515	1.00
12_S	153_K	0.514	1.00
107_V	111_R	0.514	1.00
384_A	410_F	0.513	1.00
333_V	337_T	0.513	1.00
443_S	446_T	0.512	1.00
255_I	259_P	0.511	1.00
200_Q	419_W	0.511	1.00
426_S	447_P	0.510	1.00
30_L	170_P	0.510	1.00
431_S	439_Y	0.510	1.00
74_G	219_V	0.510	1.00
86_L	439_Y	0.510	1.00
48_W	251_Q	0.509	1.00
58_I	216_H	0.509	1.00
228_P	231_N	0.508	1.00
224_E	333_V	0.508	1.00
278_F	282_A	0.507	1.00
429_L	436_F	0.507	1.00
79_P	88_G	0.507	1.00
25_F	32_A	0.505	1.00
426_S	442_F	0.504	1.00
159_N	304_G	0.503	1.00
261_E	265_H	0.502	1.00
225_V	232_I	0.501	1.00
63_A	67_A	0.500	1.00
435_M	447_P	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8019	100	0.342	Contact Map
3giaA	1	0.8231	100	0.391	Contact Map
4djkA	2	0.8096	100	0.4	Contact Map
2jlnA	1	0.7962	99.2	0.86	Contact Map
3dh4A	3	0.8731	98.7	0.881	Contact Map
2xq2A	2	0.8885	98.5	0.889	Contact Map
4wgvA	2	0.7038	97.6	0.912	Contact Map
4xp4A	1	0.8404	97.1	0.919	Contact Map
2a65A	2	0.8173	96.4	0.926	Contact Map
4us3A	1	0.7481	96.4	0.926	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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