O16G1 - BACSU - GREMLIN Contacts

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O16G1 - Oligo-1,6-glucosidase 1

UniProt:	O06994	Sequences: MSEWWKEAVVYQIYPRSFYDANGDGFGDLQGVIQKLDYIKNLGADVIWLSPVFDSPQDDNGYDISDYKNMYEKFGTNEDMFQLIDEVHKRGMKIVMDLVVNHTSDEHAWFAESRKSKDNPYRDYYLWKDPKPDGSEPNNWGSIFSGSAWTYDEGTGQYYLHYFSKKQPDLNWENEAVRREVYDVMRFWMDRGVDGWRMDVIGSISKYTDFPDYETDHSRSYIVGRYHSNGPRLHEFIQEMNREVLSHYDCMTVGEANGSDIEEAKKYTDASRQELNMIFTFEHMDIDKEQNSPNGKWQIKPFDLIALKKTMTRWQTGLMNVGWNTLYFENHDQPRVISRWGNDRKLRKECAKAFATVLHGMKGTPFIYQGEEIGMVNSDMPLEMYDDLEIKNAYRELVVENKTMSEKEFVKAVMIKGRDHARTPMQWDAGKHAGFTAGDPWIPVNSRYQDINVKESLEDQDSIFFYYQKLIQLRKQYKIMIYGDYQLLQENDPQVFSYLREYRGEKLLVVVNLSEEKALFEAPPELIHERWKVLISNYPQERADLKSISLKPYEAVMGISI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	561 (497)
Sequences:	7907 (5268)
Seq/√Len:	236.3

ECOLI - TREC SUCP MALZ YGAQ GLGX AMY2 AMY1 GLGB
BACSU - O16G1 O16G3 O16G2 TREC BBMA PULA GLGB AMY
SULSO - TREZ Q7LX99

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
37_D	90_R	4.878	1.00
19_Y	35_K	4.838	1.00
129_D	157_Q	4.712	1.00
81_F	191_R	4.518	1.00
30_Q	82_Q	4.093	1.00
88_H	194_D	4.061	1.00
86_E	89_K	4.006	1.00
54_D	69_N	3.715	1.00
103_T	125_Y	3.468	1.00
86_E	90_R	3.334	1.00
356_T	466_Y	3.309	1.00
19_Y	34_Q	3.194	1.00
54_D	65_S	3.041	1.00
87_V	94_I	3.000	1.00
39_I	44_A	2.963	1.00
30_Q	33_I	2.954	1.00
87_V	92_M	2.889	1.00
150_T	165_K	2.886	1.00
178_R	239_E	2.790	1.00
80_M	84_I	2.578	1.00
122_R	155_T	2.564	1.00
373_I	453_V	2.470	1.00
465_F	468_Q	2.416	1.00
76_T	79_D	2.388	1.00
58_D	166_K	2.388	1.00
234_H	274_E	2.383	1.00
68_K	183_D	2.374	1.00
106_E	166_K	2.358	1.00
329_E	371_E	2.345	1.00
108_A	112_E	2.321	1.00
356_T	555_A	2.308	1.00
41_N	468_Q	2.291	1.00
33_I	86_E	2.280	1.00
13_I	32_V	2.262	1.00
77_N	191_R	2.239	1.00
486_Q	499_L	2.204	1.00
499_L	506_K	2.152	1.00
100_V	181_V	2.128	1.00
30_Q	79_D	2.126	1.00
472_Q	476_Q	2.109	1.00
353_A	511_V	2.076	1.00
103_T	170_L	2.076	1.00
82_Q	86_E	2.068	1.00
232_R	235_E	2.049	1.00
152_D	155_T	2.047	1.00
180_E	183_D	2.025	1.00
8_A	45_D	1.989	1.00
36_L	90_R	1.976	1.00
241_N	245_L	1.959	1.00
151_Y	156_G	1.958	1.00
114_R	152_D	1.954	1.00
390_I	413_V	1.950	1.00
357_V	511_V	1.939	1.00
23_G	437_A	1.939	1.00
52_V	96_M	1.902	1.00
458_E	465_F	1.886	1.00
124_Y	180_E	1.884	1.00
245_L	248_Y	1.861	1.00
45_D	475_K	1.855	1.00
58_D	164_S	1.855	1.00
185_M	240_M	1.849	1.00
182_Y	239_E	1.842	1.00
429_A	454_K	1.838	1.00
33_I	82_Q	1.833	1.00
551_K	554_E	1.833	1.00
186_R	190_D	1.824	1.00
384_M	443_P	1.815	1.00
381_P	384_M	1.815	1.00
47_I	87_V	1.809	1.00
186_R	247_H	1.805	1.00
41_N	457_L	1.800	1.00
112_E	121_Y	1.781	1.00
497_S	510_V	1.775	1.00
32_V	83_L	1.772	1.00
36_L	87_V	1.753	1.00
337_I	351_A	1.751	1.00
486_Q	501_E	1.749	1.00
457_L	464_F	1.748	1.00
501_E	506_K	1.737	1.00
26_F	73_K	1.724	1.00
386_D	442_I	1.718	1.00
112_E	119_N	1.714	1.00
484_D	501_E	1.712	1.00
348_K	352_K	1.709	1.00
355_A	467_Y	1.706	1.00
428_D	454_K	1.702	1.00
40_K	90_R	1.700	1.00
173_E	232_R	1.696	1.00
78_E	81_F	1.672	1.00
105_D	166_K	1.664	1.00
186_R	243_E	1.660	1.00
360_G	498_Y	1.653	1.00
85_D	89_K	1.648	1.00
189_M	250_C	1.627	1.00
9_V	471_I	1.612	1.00
494_Q	514_S	1.604	1.00
499_L	508_L	1.588	1.00
108_A	111_A	1.582	1.00
69_N	77_N	1.576	1.00
53_F	96_M	1.571	1.00
121_Y	124_Y	1.570	1.00
376_V	447_R	1.561	1.00
112_E	115_K	1.557	1.00
179_R	183_D	1.557	1.00
10_V	46_V	1.554	1.00
453_V	464_F	1.552	1.00
68_K	187_F	1.552	1.00
52_V	70_M	1.537	1.00
120_P	176_A	1.523	1.00
519_L	547_S	1.520	1.00
41_N	464_F	1.516	1.00
432_H	438_G	1.512	1.00
533_V	536_S	1.509	1.00
68_K	184_V	1.498	1.00
457_L	465_F	1.486	1.00
190_D	247_H	1.485	1.00
179_R	243_E	1.485	1.00
7_E	482_Y	1.472	1.00
54_D	66_D	1.463	1.00
58_D	106_E	1.459	1.00
57_Q	71_Y	1.456	1.00
456_S	465_F	1.456	1.00
464_F	468_Q	1.448	1.00
432_H	436_T	1.441	1.00
243_E	247_H	1.435	1.00
312_T	485_Y	1.427	1.00
180_E	184_V	1.419	1.00
459_D	465_F	1.405	1.00
103_T	177_V	1.402	1.00
519_L	549_S	1.402	1.00
33_I	83_L	1.397	1.00
30_Q	34_Q	1.396	1.00
469_K	472_Q	1.394	1.00
68_K	180_E	1.388	1.00
66_D	69_N	1.384	1.00
122_R	152_D	1.383	1.00
360_G	480_M	1.371	1.00
494_Q	518_A	1.369	1.00
113_S	155_T	1.358	1.00
80_M	96_M	1.357	1.00
238_Q	274_E	1.353	1.00
105_D	168_P	1.341	1.00
238_Q	273_Q	1.338	1.00
52_V	80_M	1.336	1.00
176_A	179_R	1.335	1.00
425_M	453_V	1.324	1.00
309_K	313_R	1.318	1.00
374_G	463_I	1.317	1.00
329_E	336_V	1.316	1.00
232_R	236_F	1.311	1.00
80_M	193_V	1.308	1.00
375_M	426_Q	1.304	1.00
8_A	46_V	1.298	1.00
479_I	507_L	1.291	1.00
511_V	555_A	1.289	1.00
353_A	513_L	1.285	1.00
54_D	72_E	1.284	1.00
175_E	179_R	1.277	1.00
12_Q	50_S	1.270	1.00
116_S	119_N	1.257	1.00
95_V	251_M	1.256	1.00
13_I	39_I	1.255	1.00
39_I	47_I	1.252	1.00
380_M	384_M	1.242	1.00
517_K	549_S	1.234	1.00
323_W	364_T	1.232	1.00
7_E	481_I	1.227	1.00
111_A	114_R	1.226	1.00
328_F	354_F	1.226	1.00
106_E	111_A	1.223	1.00
348_K	459_D	1.218	1.00
266_K	272_R	1.215	1.00
57_Q	73_K	1.215	1.00
32_V	49_L	1.213	1.00
100_V	185_M	1.213	1.00
115_K	119_N	1.207	1.00
263_E	266_K	1.192	1.00
190_D	248_Y	1.187	1.00
356_T	470_L	1.181	1.00
16_R	73_K	1.179	1.00
112_E	116_S	1.178	1.00
81_F	85_D	1.174	1.00
123_D	174_N	1.170	1.00
351_A	463_I	1.166	1.00
477_Y	505_E	1.165	1.00
70_M	80_M	1.164	1.00
352_K	466_Y	1.162	1.00
117_K	157_Q	1.150	1.00
482_Y	502_Y	1.148	1.00
538_Y	551_K	1.139	1.00
15_P	32_V	1.136	1.00
130_P	137_P	1.133	1.00
305_I	309_K	1.133	1.00
468_Q	472_Q	1.130	1.00
342_N	515_E	1.126	1.00
130_P	136_E	1.123	1.00
253_V	366_F	1.121	1.00
312_T	487_L	1.121	1.00
130_P	151_Y	1.110	1.00
163_F	203_S	1.107	1.00
523_P	526_L	1.106	1.00
111_A	115_K	1.106	1.00
179_R	182_Y	1.101	1.00
479_I	505_E	1.097	1.00
20_D	25_G	1.087	1.00
172_W	181_V	1.083	1.00
153_E	156_G	1.082	1.00
382_L	385_Y	1.081	1.00
359_H	471_I	1.074	1.00
113_S	127_W	1.072	1.00
49_L	52_V	1.068	1.00
336_V	340_W	1.067	1.00
243_E	248_Y	1.065	1.00
480_M	507_L	1.064	1.00
189_M	248_Y	1.062	1.00
205_S	232_R	1.057	1.00
385_Y	414_M	1.057	1.00
360_G	470_L	1.051	1.00
305_I	493_P	1.051	1.00
479_I	502_Y	1.048	1.00
514_S	518_A	1.046	1.00
54_D	71_Y	1.044	1.00
540_Q	551_K	1.041	1.00
238_Q	272_R	1.041	1.00
385_Y	390_I	1.040	1.00
241_N	246_S	1.039	1.00
477_Y	507_L	1.039	1.00
178_R	236_F	1.039	1.00
498_Y	509_V	1.038	1.00
346_L	349_E	1.038	1.00
116_S	155_T	1.032	1.00
29_L	52_V	1.026	1.00
100_V	198_M	1.024	1.00
312_T	316_T	1.018	1.00
507_L	534_L	1.010	1.00
201_I	204_I	1.007	1.00
205_S	230_G	1.004	1.00
319_M	484_D	1.001	1.00
521_E	547_S	1.000	1.00
40_K	92_M	0.997	1.00
119_N	122_R	0.996	1.00
98_L	185_M	0.995	1.00
384_M	439_D	0.995	1.00
79_D	82_Q	0.991	1.00
378_S	414_M	0.989	1.00
306_A	309_K	0.988	1.00
533_V	537_N	0.985	1.00
33_I	37_D	0.985	1.00
533_V	538_Y	0.984	1.00
44_A	92_M	0.981	1.00
44_A	47_I	0.980	1.00
35_K	38_Y	0.977	1.00
124_Y	176_A	0.970	1.00
261_I	317_G	0.969	1.00
46_V	251_M	0.968	1.00
21_A	30_Q	0.966	1.00
40_K	91_G	0.966	1.00
136_E	147_S	0.963	1.00
29_L	70_M	0.963	1.00
148_A	160_L	0.960	1.00
115_K	121_Y	0.960	1.00
237_I	240_M	0.958	1.00
181_V	184_V	0.954	1.00
200_V	203_S	0.953	1.00
494_Q	516_E	0.951	1.00
123_D	171_N	0.951	1.00
95_V	195_G	0.949	1.00
198_M	275_L	0.948	1.00
201_I	237_I	0.948	1.00
58_D	105_D	0.947	1.00
319_M	362_K	0.947	1.00
357_V	513_L	0.947	1.00
84_I	94_I	0.943	1.00
457_L	468_Q	0.941	1.00
173_E	236_F	0.934	1.00
131_K	137_P	0.933	1.00
429_A	455_E	0.924	1.00
178_R	182_Y	0.922	1.00
37_D	86_E	0.921	1.00
454_K	458_E	0.921	1.00
29_L	80_M	0.920	1.00
36_L	86_E	0.916	1.00
242_R	246_S	0.913	1.00
121_Y	176_A	0.913	1.00
23_G	438_G	0.913	1.00
77_N	187_F	0.912	1.00
15_P	50_S	0.911	1.00
22_N	26_F	0.911	1.00
117_K	129_D	0.910	1.00
184_V	187_F	0.909	1.00
359_H	365_P	0.904	1.00
10_V	366_F	0.904	1.00
16_R	57_Q	0.900	1.00
117_K	122_R	0.898	1.00
205_S	236_F	0.892	0.99
487_L	490_E	0.892	0.99
452_N	455_E	0.892	0.99
303_D	306_A	0.892	0.99
466_Y	555_A	0.889	0.99
117_K	155_T	0.889	0.99
185_M	244_V	0.887	0.99
282_E	313_R	0.886	0.99
15_P	49_L	0.885	0.99
390_I	417_G	0.884	0.99
147_S	150_T	0.883	0.99
182_Y	240_M	0.880	0.99
243_E	246_S	0.879	0.99
182_Y	243_E	0.877	0.99
303_D	493_P	0.871	0.99
78_E	82_Q	0.870	0.99
266_K	269_D	0.867	0.99
80_M	83_L	0.866	0.99
352_K	463_I	0.866	0.99
236_F	240_M	0.865	0.99
112_E	120_P	0.863	0.99
341_G	350_C	0.863	0.99
83_L	94_I	0.863	0.99
244_V	247_H	0.863	0.99
373_I	426_Q	0.863	0.99
533_V	540_Q	0.862	0.99
57_Q	74_F	0.861	0.99
453_V	457_L	0.860	0.99
251_M	277_M	0.859	0.99
77_N	81_F	0.857	0.99
492_D	518_A	0.856	0.99
122_R	157_Q	0.856	0.99
30_Q	76_T	0.855	0.99
510_V	548_I	0.855	0.99
87_V	90_R	0.854	0.99
71_Y	74_F	0.852	0.99
234_H	238_Q	0.849	0.99
229_N	263_E	0.844	0.99
465_F	469_K	0.844	0.99
115_K	154_G	0.841	0.99
358_L	365_P	0.840	0.99
39_I	92_M	0.835	0.99
21_A	24_D	0.834	0.99
151_Y	155_T	0.834	0.99
82_Q	85_D	0.833	0.99
187_F	191_R	0.833	0.99
349_E	538_Y	0.831	0.99
378_S	385_Y	0.831	0.99
433_A	444_V	0.830	0.99
114_R	155_T	0.830	0.99
12_Q	15_P	0.829	0.99
29_L	83_L	0.827	0.99
113_S	122_R	0.823	0.99
436_T	439_D	0.821	0.99
485_Y	496_F	0.821	0.99
305_I	308_K	0.820	0.99
207_Y	226_Y	0.818	0.99
328_F	357_V	0.817	0.99
373_I	456_S	0.816	0.99
244_V	248_Y	0.814	0.99
56_P	65_S	0.812	0.99
538_Y	554_E	0.809	0.99
238_Q	242_R	0.803	0.99
284_M	287_D	0.802	0.99
488_L	508_L	0.801	0.99
33_I	90_R	0.799	0.99
138_N	209_D	0.798	0.99
96_M	193_V	0.791	0.99
164_S	167_Q	0.788	0.99
46_V	93_K	0.788	0.99
37_D	41_N	0.788	0.99
20_D	24_D	0.787	0.99
38_Y	453_V	0.786	0.99
300_K	306_A	0.785	0.99
202_G	256_A	0.785	0.99
100_V	184_V	0.782	0.99
488_L	499_L	0.779	0.99
367_I	467_Y	0.779	0.99
497_S	508_L	0.778	0.99
426_Q	444_V	0.776	0.99
501_E	504_G	0.775	0.99
15_P	29_L	0.775	0.99
517_K	551_K	0.774	0.99
179_R	239_E	0.774	0.99
307_L	311_M	0.774	0.99
360_G	509_V	0.774	0.99
347_R	456_S	0.767	0.98
269_D	273_Q	0.767	0.98
428_D	432_H	0.766	0.98
376_V	451_I	0.766	0.98
390_I	414_M	0.765	0.98
142_S	146_G	0.763	0.98
202_G	257_N	0.762	0.98
85_D	88_H	0.761	0.98
9_V	44_A	0.759	0.98
4_W	8_A	0.759	0.98
164_S	169_D	0.758	0.98
277_M	364_T	0.758	0.98
456_S	459_D	0.755	0.98
116_S	122_R	0.753	0.98
480_M	483_G	0.753	0.98
115_K	152_D	0.752	0.98
170_L	177_V	0.752	0.98
356_T	360_G	0.748	0.98
203_S	228_S	0.748	0.98
19_Y	31_G	0.748	0.98
311_M	361_M	0.748	0.98
84_I	193_V	0.747	0.98
9_V	359_H	0.745	0.98
308_K	312_T	0.744	0.98
460_Q	465_F	0.743	0.98
536_S	539_P	0.740	0.98
29_L	79_D	0.739	0.98
257_N	333_Q	0.738	0.98
429_A	432_H	0.737	0.98
338_S	341_G	0.737	0.98
173_E	205_S	0.737	0.98
473_L	477_Y	0.735	0.98
355_A	463_I	0.732	0.98
162_Y	227_H	0.732	0.98
328_F	336_V	0.731	0.98
455_E	459_D	0.731	0.98
93_K	194_D	0.729	0.98
21_A	83_L	0.728	0.98
382_L	390_I	0.728	0.98
306_A	310_T	0.727	0.98
114_R	154_G	0.723	0.98
176_A	180_E	0.722	0.98
536_S	554_E	0.722	0.98
495_V	520_F	0.721	0.98
186_R	248_Y	0.720	0.98
254_G	275_L	0.720	0.98
179_R	186_R	0.712	0.97
197_R	332_D	0.712	0.97
359_H	470_L	0.712	0.97
423_T	426_Q	0.711	0.97
119_N	155_T	0.709	0.97
279_F	366_F	0.708	0.97
285_D	288_K	0.708	0.97
536_S	540_Q	0.707	0.97
21_A	32_V	0.707	0.97
447_R	451_I	0.707	0.97
436_T	440_P	0.706	0.97
88_H	93_K	0.706	0.97
127_W	152_D	0.705	0.97
109_W	170_L	0.699	0.97
204_I	233_L	0.699	0.97
299_I	302_F	0.699	0.97
531_W	534_L	0.695	0.97
432_H	439_D	0.694	0.97
230_G	233_L	0.693	0.97
55_S	59_D	0.692	0.97
429_A	452_N	0.692	0.97
38_Y	44_A	0.691	0.97
310_T	313_R	0.690	0.97
49_L	80_M	0.689	0.97
123_D	126_L	0.689	0.97
36_L	92_M	0.689	0.97
537_N	540_Q	0.688	0.97
510_V	550_L	0.688	0.97
426_Q	433_A	0.687	0.97
38_Y	464_F	0.684	0.97
268_T	322_G	0.681	0.97
101_N	169_D	0.681	0.97
429_A	449_Q	0.680	0.97
113_S	119_N	0.679	0.97
47_I	83_L	0.679	0.97
478_K	482_Y	0.675	0.97
489_Q	492_D	0.675	0.97
300_K	303_D	0.674	0.97
315_Q	362_K	0.673	0.96
336_V	371_E	0.673	0.96
114_R	117_K	0.672	0.96
138_N	148_A	0.671	0.96
186_R	244_V	0.670	0.96
279_F	284_M	0.670	0.96
200_V	204_I	0.669	0.96
349_E	352_K	0.666	0.96
413_V	417_G	0.665	0.96
531_W	536_S	0.664	0.96
94_I	194_D	0.664	0.96
532_K	540_Q	0.664	0.96
21_A	34_Q	0.664	0.96
189_M	244_V	0.664	0.96
448_Y	452_N	0.663	0.96
62_Y	199_D	0.663	0.96
550_L	554_E	0.661	0.96
263_E	268_T	0.661	0.96
199_D	332_D	0.661	0.96
385_Y	417_G	0.660	0.96
143_I	228_S	0.660	0.96
77_N	80_M	0.660	0.96
181_V	201_I	0.658	0.96
371_E	467_Y	0.658	0.96
316_T	486_Q	0.657	0.96
131_K	136_E	0.657	0.96
265_K	321_V	0.656	0.96
328_F	358_L	0.656	0.96
343_D	347_R	0.655	0.96
45_D	92_M	0.654	0.96
185_M	198_M	0.652	0.96
46_V	95_V	0.652	0.96
199_D	331_H	0.652	0.96
49_L	83_L	0.651	0.96
286_I	310_T	0.650	0.96
367_I	471_I	0.650	0.96
8_A	93_K	0.650	0.96
304_L	308_K	0.650	0.96
169_D	172_W	0.649	0.96
229_N	267_Y	0.649	0.96
456_S	462_S	0.648	0.96
10_V	95_V	0.648	0.96
532_K	536_S	0.647	0.96
117_K	120_P	0.647	0.96
348_K	461_D	0.645	0.96
533_V	539_P	0.645	0.96
239_E	243_E	0.644	0.95
99_V	102_H	0.643	0.95
22_N	28_D	0.642	0.95
164_S	388_L	0.642	0.95
499_L	502_Y	0.641	0.95
348_K	463_I	0.640	0.95
152_D	157_Q	0.639	0.95
57_Q	60_N	0.638	0.95
207_Y	230_G	0.636	0.95
167_Q	171_N	0.635	0.95
334_P	339_R	0.634	0.95
143_I	203_S	0.631	0.95
163_F	167_Q	0.630	0.95
33_I	79_D	0.629	0.95
244_V	252_T	0.629	0.95
242_R	245_L	0.628	0.95
62_Y	332_D	0.628	0.95
378_S	446_S	0.628	0.95
355_A	367_I	0.628	0.95
347_R	350_C	0.627	0.95
433_A	452_N	0.626	0.95
130_P	158_Y	0.623	0.95
245_L	276_N	0.623	0.95
356_T	511_V	0.622	0.95
33_I	87_V	0.619	0.94
7_E	478_K	0.618	0.94
535_I	538_Y	0.618	0.94
98_L	198_M	0.618	0.94
165_K	169_D	0.617	0.94
62_Y	197_R	0.616	0.94
283_H	307_L	0.616	0.94
162_Y	203_S	0.615	0.94
334_P	340_W	0.613	0.94
118_D	121_Y	0.613	0.94
241_N	247_H	0.613	0.94
235_E	240_M	0.612	0.94
385_Y	413_V	0.612	0.94
282_E	285_D	0.611	0.94
478_K	505_E	0.611	0.94
16_R	74_F	0.609	0.94
177_V	180_E	0.608	0.94
478_K	481_I	0.608	0.94
447_R	450_D	0.607	0.94
261_I	268_T	0.607	0.94
142_S	148_A	0.607	0.94
197_R	331_H	0.605	0.94
36_L	47_I	0.605	0.94
38_Y	457_L	0.604	0.94
369_Q	425_M	0.604	0.94
284_M	327_Y	0.602	0.94
418_R	422_R	0.601	0.94
359_H	371_E	0.601	0.94
130_P	133_D	0.601	0.94
334_P	338_S	0.599	0.93
28_D	31_G	0.598	0.93
127_W	130_P	0.598	0.93
336_V	354_F	0.597	0.93
116_S	120_P	0.595	0.93
433_A	448_Y	0.594	0.93
116_S	121_Y	0.594	0.93
360_G	511_V	0.594	0.93
107_H	110_F	0.594	0.93
177_V	184_V	0.594	0.93
311_M	315_Q	0.593	0.93
350_C	353_A	0.593	0.93
461_D	539_P	0.593	0.93
20_D	28_D	0.592	0.93
173_E	208_T	0.591	0.93
121_Y	180_E	0.590	0.93
269_D	272_R	0.588	0.93
313_R	317_G	0.587	0.93
455_E	458_E	0.586	0.93
428_D	448_Y	0.585	0.93
102_H	331_H	0.585	0.93
69_N	78_E	0.585	0.93
237_I	241_N	0.584	0.93
432_H	444_V	0.584	0.93
13_I	50_S	0.581	0.92
233_L	237_I	0.581	0.92
29_L	49_L	0.580	0.92
461_D	465_F	0.579	0.92
178_R	205_S	0.579	0.92
263_E	269_D	0.576	0.92
304_L	307_L	0.576	0.92
21_A	28_D	0.576	0.92
261_I	266_K	0.575	0.92
534_L	537_N	0.574	0.92
186_R	246_S	0.574	0.92
198_M	245_L	0.573	0.92
183_D	190_D	0.573	0.92
545_L	548_I	0.573	0.92
182_Y	186_R	0.571	0.92
112_E	118_D	0.570	0.92
428_D	452_N	0.570	0.92
113_S	152_D	0.570	0.92
502_Y	505_E	0.568	0.92
510_V	520_F	0.568	0.92
151_Y	154_G	0.568	0.92
456_S	464_F	0.567	0.91
54_D	74_F	0.567	0.91
379_D	385_Y	0.567	0.91
390_I	416_K	0.566	0.91
345_K	349_E	0.566	0.91
84_I	194_D	0.566	0.91
353_A	553_Y	0.564	0.91
531_W	540_Q	0.564	0.91
310_T	314_W	0.562	0.91
65_S	106_E	0.562	0.91
254_G	278_I	0.562	0.91
84_I	88_H	0.562	0.91
168_P	171_N	0.562	0.91
284_M	288_K	0.562	0.91
515_E	553_Y	0.561	0.91
84_I	96_M	0.561	0.91
311_M	314_W	0.561	0.91
56_P	59_D	0.560	0.91
444_V	448_Y	0.560	0.91
316_T	319_M	0.559	0.91
137_P	140_W	0.558	0.91
373_I	463_I	0.558	0.91
431_K	436_T	0.557	0.91
385_Y	388_L	0.557	0.91
109_W	180_E	0.555	0.91
335_R	338_S	0.555	0.91
47_I	92_M	0.555	0.91
10_V	364_T	0.555	0.91
312_T	315_Q	0.555	0.91
138_N	208_T	0.554	0.90
287_D	416_K	0.553	0.90
489_Q	495_V	0.553	0.90
172_W	204_I	0.552	0.90
102_H	197_R	0.552	0.90
521_E	545_L	0.552	0.90
98_L	184_V	0.552	0.90
6_K	482_Y	0.551	0.90
9_V	365_P	0.549	0.90
280_T	284_M	0.549	0.90
260_D	263_E	0.548	0.90
261_I	269_D	0.548	0.90
24_D	28_D	0.547	0.90
202_G	258_G	0.547	0.90
487_L	496_F	0.546	0.90
535_I	539_P	0.546	0.90
484_D	502_Y	0.545	0.90
19_Y	437_A	0.545	0.90
120_P	124_Y	0.545	0.90
251_M	276_N	0.544	0.90
532_K	535_I	0.544	0.90
265_K	268_T	0.544	0.90
356_T	509_V	0.544	0.90
281_F	284_M	0.544	0.90
485_Y	498_Y	0.542	0.90
450_D	455_E	0.542	0.90
477_Y	480_M	0.542	0.90
365_P	470_L	0.541	0.89
484_D	499_L	0.541	0.89
301_P	304_L	0.541	0.89
199_D	255_E	0.538	0.89
226_Y	230_G	0.538	0.89
100_V	240_M	0.537	0.89
27_G	31_G	0.536	0.89
167_Q	172_W	0.535	0.89
29_L	32_V	0.535	0.89
541_E	544_D	0.535	0.89
235_E	238_Q	0.534	0.89
492_D	495_V	0.534	0.89
202_G	259_S	0.534	0.89
334_P	337_I	0.533	0.89
526_L	531_W	0.533	0.89
113_S	121_Y	0.532	0.89
10_V	251_M	0.531	0.89
15_P	74_F	0.531	0.89
151_Y	157_Q	0.531	0.89
88_H	94_I	0.531	0.89
97_D	197_R	0.530	0.88
302_F	305_I	0.530	0.88
350_C	553_Y	0.530	0.88
70_M	77_N	0.529	0.88
380_M	385_Y	0.529	0.88
443_P	446_S	0.529	0.88
16_R	71_Y	0.529	0.88
496_F	511_V	0.528	0.88
46_V	92_M	0.528	0.88
177_V	181_V	0.528	0.88
49_L	87_V	0.527	0.88
202_G	228_S	0.526	0.88
102_H	199_D	0.526	0.88
41_N	465_F	0.525	0.88
424_P	427_W	0.524	0.88
41_N	472_Q	0.524	0.88
380_M	383_E	0.524	0.88
531_W	535_I	0.523	0.88
495_V	550_L	0.523	0.88
338_S	377_N	0.523	0.88
532_K	537_N	0.523	0.88
473_L	534_L	0.523	0.88
164_S	168_P	0.522	0.88
240_M	244_V	0.521	0.88
229_N	258_G	0.521	0.88
311_M	496_F	0.517	0.87
22_N	30_Q	0.517	0.87
26_F	57_Q	0.516	0.87
233_L	236_F	0.516	0.87
307_L	328_F	0.515	0.87
333_Q	421_A	0.514	0.87
359_H	367_I	0.514	0.87
461_D	469_K	0.513	0.87
70_M	96_M	0.511	0.87
273_Q	276_N	0.511	0.87
78_E	191_R	0.511	0.87
351_A	355_A	0.511	0.87
183_D	186_R	0.510	0.87
240_M	243_E	0.510	0.87
98_L	181_V	0.509	0.86
241_N	276_N	0.508	0.86
335_R	339_R	0.508	0.86
39_I	471_I	0.508	0.86
495_V	518_A	0.507	0.86
520_F	548_I	0.507	0.86
384_M	390_I	0.507	0.86
325_T	366_F	0.506	0.86
278_I	282_E	0.506	0.86
64_I	99_V	0.506	0.86
275_L	281_F	0.506	0.86
309_K	312_T	0.505	0.86
342_N	350_C	0.505	0.86
280_T	327_Y	0.505	0.86
142_S	145_S	0.504	0.86
18_F	39_I	0.504	0.86
241_N	244_V	0.504	0.86
62_Y	331_H	0.504	0.86
336_V	467_Y	0.503	0.86
38_Y	41_N	0.502	0.86
257_N	285_D	0.500	0.85
302_F	306_A	0.500	0.85
209_D	226_Y	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4mb1A	1	0.9929	100	0.152	Contact Map
2ze0A	2	0.9394	100	0.169	Contact Map
1uokA	1	0.9911	100	0.17	Contact Map
3aj7A	1	0.9911	100	0.185	Contact Map
4hphA	1	0.9822	100	0.186	Contact Map
3wy2A	1	0.9269	100	0.188	Contact Map
4aieA	1	0.9537	100	0.19	Contact Map
2zicA	1	0.9465	100	0.197	Contact Map
1zjaA	1	0.9804	100	0.2	Contact Map
3zo9A	4	0.8895	100	0.22	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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