BBMA - BACSU - GREMLIN Contacts

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BBMA - Intracellular maltogenic amylase

UniProt:	O06988	Sequences: MEYAAIHHQPFSTDAYSYDGRTVHIKIRTKKGDADHIRFIWGDPYEYNDGKWSANEQPMRKIAATEMHDYWFAEVVPPFRRLQYAFVVTDDHEDIFFGSSGVCPYNEKTLETIHYYFKFPFVHEADTFQAPEWVKSTVWYQIFPERFANGREDLSPKNALPWGSKDPDVNDFFGGDLQGIVDKLDYLEDLGVNGIYLTPIFSAPSNHKYDTLDYFSIDPHFGDPELFRTLVSQLHQRGMRIMLDAVFNHIGSASPQWQDVVKNGDQSRYKDWFHIHSFPVTDDNYDRFAFTADMPKLNTANPEVQKYLLDIALYWIREFDIDGWRLDVANEVDHVFWKTFRQAVSTEKPDVYILGEIWHSAEPWLRGDEFHAAMNYPFTEPMIEYFADQTISASRMAHRVNAHLMNGMKQANEVMFNLLDSHDTKRLLTRCRNDEKKARALLAFMFAQTGSPCIYYGTEIGLNGENDPLCRKCMVWEKEKQNQDMLQFMKRLIALRKQENTLLTEGHLEWNLLDDKNDFISFSRTLDEKILIYFFNQGNVVQHVSLRELNIDRNKKICDAWTEQPLQHHDVIAVQPGEFLILSAAAPV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	588 (519)
Sequences:	10779 (7413)
Seq/√Len:	325.4

ECOLI - MALZ GLGX GLGB YGAQ TREC AMY1 SUCP AMY2
BACSU - BBMA PULA GLGB O16G3 O16G2 TREC O16G1 AMY
SULSO - Q7LX99 TREZ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
185_D	237_R	4.407	1.00
233_Q	236_Q	4.143	1.00
178_Q	229_T	4.121	1.00
178_Q	226_L	3.719	1.00
189_D	490_K	3.602	1.00
443_A	579_F	3.541	1.00
305_Q	339_T	3.307	1.00
188_E	237_R	3.292	1.00
223_D	226_L	3.188	1.00
447_A	522_F	3.024	1.00
195_I	234_L	2.927	1.00
442_L	489_M	2.864	1.00
461_G	485_M	2.846	1.00
148_A	183_K	2.840	1.00
233_Q	237_R	2.772	1.00
447_A	581_I	2.759	1.00
345_S	371_H	2.676	1.00
494_A	498_Q	2.618	1.00
184_L	237_R	2.546	1.00
227_F	231_V	2.480	1.00
228_R	318_E	2.464	1.00
420_D	458_T	2.350	1.00
24_H	74_E	2.327	1.00
306_K	310_D	2.325	1.00
181_V	229_T	2.323	1.00
314_Y	319_F	2.280	1.00
235_H	322_D	2.219	1.00
229_T	233_Q	2.216	1.00
180_I	230_L	2.208	1.00
316_I	351_V	2.148	1.00
227_F	321_I	2.130	1.00
178_Q	181_V	2.118	1.00
543_H	571_V	2.098	1.00
181_V	233_Q	2.087	1.00
363_P	366_R	2.079	1.00
514_D	517_N	2.076	1.00
447_A	533_Y	2.070	1.00
197_L	200_I	2.070	1.00
313_L	343_A	2.061	1.00
187_L	192_V	2.052	1.00
535_F	579_F	2.044	1.00
469_L	472_K	2.039	1.00
126_D	320_D	2.021	1.00
138_V	493_I	2.002	1.00
446_F	493_I	1.993	1.00
225_E	228_R	1.970	1.00
499_E	529_K	1.952	1.00
487_Q	490_K	1.922	1.00
468_P	472_K	1.914	1.00
142_I	147_F	1.892	1.00
556_K	559_D	1.885	1.00
343_A	346_T	1.870	1.00
130_A	133_W	1.868	1.00
344_V	351_V	1.845	1.00
38_R	87_V	1.844	1.00
435_E	482_N	1.841	1.00
472_K	476_W	1.835	1.00
250_I	273_F	1.794	1.00
247_F	311_I	1.787	1.00
491_R	494_A	1.782	1.00
439_R	488_F	1.774	1.00
226_L	229_T	1.764	1.00
137_T	194_G	1.754	1.00
124_E	320_D	1.736	1.00
475_V	478_K	1.726	1.00
25_I	78_P	1.724	1.00
317_R	347_E	1.721	1.00
523_S	530_I	1.702	1.00
556_K	582_L	1.699	1.00
107_E	111_E	1.691	1.00
115_Y	118_K	1.689	1.00
178_Q	182_D	1.685	1.00
499_E	531_L	1.677	1.00
487_Q	491_R	1.676	1.00
189_D	486_L	1.672	1.00
180_I	197_L	1.664	1.00
197_L	230_L	1.660	1.00
521_S	534_F	1.660	1.00
510_W	513_L	1.657	1.00
79_F	82_L	1.654	1.00
474_M	478_K	1.652	1.00
122_V	232_S	1.651	1.00
63_A	73_A	1.648	1.00
129_Q	133_W	1.647	1.00
227_F	230_L	1.623	1.00
228_R	319_F	1.608	1.00
215_F	311_I	1.606	1.00
230_L	234_L	1.603	1.00
470_C	473_C	1.594	1.00
28_R	72_F	1.587	1.00
122_V	125_A	1.584	1.00
523_S	532_I	1.582	1.00
144_P	180_I	1.575	1.00
234_L	241_I	1.574	1.00
469_L	473_C	1.574	1.00
182_D	233_Q	1.568	1.00
136_S	504_T	1.562	1.00
202_S	219_P	1.543	1.00
312_A	340_F	1.542	1.00
29_T	37_I	1.526	1.00
341_R	345_S	1.526	1.00
234_L	239_M	1.524	1.00
313_L	317_R	1.524	1.00
37_I	88_V	1.524	1.00
27_I	86_F	1.518	1.00
460_I	474_M	1.510	1.00
40_I	87_V	1.506	1.00
314_Y	318_E	1.489	1.00
474_M	477_E	1.484	1.00
418_L	421_S	1.478	1.00
142_I	180_I	1.477	1.00
483_Q	487_Q	1.477	1.00
232_S	236_Q	1.465	1.00
427_L	431_C	1.455	1.00
21_R	74_E	1.455	1.00
467_D	472_K	1.454	1.00
298_N	301_N	1.453	1.00
486_L	490_K	1.449	1.00
437_K	577_G	1.448	1.00
545_S	569_H	1.447	1.00
548_E	570_D	1.444	1.00
468_P	471_R	1.440	1.00
339_T	343_A	1.430	1.00
187_L	195_I	1.428	1.00
187_L	239_M	1.426	1.00
297_L	304_V	1.422	1.00
137_T	352_Y	1.416	1.00
309_L	343_A	1.403	1.00
533_Y	581_I	1.396	1.00
468_P	473_C	1.395	1.00
142_I	187_L	1.394	1.00
36_H	89_T	1.393	1.00
78_P	82_L	1.393	1.00
428_L	438_A	1.384	1.00
114_H	118_K	1.379	1.00
336_F	340_F	1.379	1.00
200_I	227_F	1.372	1.00
495_L	557_I	1.362	1.00
545_S	571_V	1.359	1.00
439_R	485_M	1.357	1.00
42_G	82_L	1.356	1.00
511_N	532_I	1.351	1.00
186_Y	486_L	1.348	1.00
425_K	429_T	1.347	1.00
277_S	282_D	1.344	1.00
428_L	432_R	1.343	1.00
443_A	488_F	1.337	1.00
518_D	538_G	1.327	1.00
215_F	310_D	1.326	1.00
543_H	573_A	1.325	1.00
202_S	216_S	1.321	1.00
426_R	429_T	1.319	1.00
36_H	62_I	1.317	1.00
316_I	344_V	1.314	1.00
335_V	338_K	1.288	1.00
144_P	197_L	1.288	1.00
551_I	554_N	1.285	1.00
217_I	227_F	1.283	1.00
227_F	243_L	1.282	1.00
271_D	274_H	1.263	1.00
173_F	179_G	1.263	1.00
177_L	217_I	1.258	1.00
541_V	573_A	1.256	1.00
125_A	232_S	1.254	1.00
320_D	348_K	1.253	1.00
137_T	193_N	1.249	1.00
40_I	97_F	1.246	1.00
29_T	88_V	1.242	1.00
194_G	242_M	1.235	1.00
572_I	582_L	1.233	1.00
313_L	347_E	1.225	1.00
252_S	287_R	1.224	1.00
386_F	441_L	1.223	1.00
439_R	484_D	1.223	1.00
509_E	525_T	1.220	1.00
202_S	218_D	1.216	1.00
245_A	312_A	1.216	1.00
435_E	439_R	1.215	1.00
224_P	319_F	1.212	1.00
142_I	195_I	1.193	1.00
87_V	97_F	1.190	1.00
242_M	354_L	1.186	1.00
194_G	240_R	1.186	1.00
316_I	348_K	1.183	1.00
541_V	576_P	1.183	1.00
139_W	416_F	1.181	1.00
26_K	74_E	1.179	1.00
501_T	531_L	1.178	1.00
28_R	70_Y	1.176	1.00
478_K	482_N	1.171	1.00
242_M	323_G	1.168	1.00
404_L	412_N	1.168	1.00
122_V	229_T	1.164	1.00
522_F	533_Y	1.163	1.00
394_S	516_K	1.159	1.00
99_S	102_V	1.155	1.00
176_D	179_G	1.154	1.00
184_L	233_Q	1.153	1.00
184_L	234_L	1.151	1.00
556_K	560_A	1.149	1.00
201_F	311_I	1.149	1.00
493_I	497_K	1.146	1.00
479_E	482_N	1.146	1.00
425_K	430_R	1.142	1.00
208_K	221_F	1.142	1.00
60_R	63_A	1.139	1.00
442_L	492_L	1.137	1.00
344_V	347_E	1.137	1.00
35_D	91_D	1.133	1.00
339_T	342_Q	1.131	1.00
201_F	211_T	1.130	1.00
472_K	475_V	1.128	1.00
419_L	441_L	1.125	1.00
296_K	299_T	1.125	1.00
190_L	486_L	1.119	1.00
303_E	306_K	1.118	1.00
473_C	476_W	1.113	1.00
183_K	186_Y	1.110	1.00
26_K	72_F	1.109	1.00
61_K	73_A	1.107	1.00
119_F	228_R	1.102	1.00
456_Y	474_M	1.100	1.00
426_R	431_C	1.099	1.00
444_F	535_F	1.095	1.00
39_F	73_A	1.094	1.00
145_E	149_N	1.092	1.00
399_R	402_A	1.090	1.00
341_R	353_I	1.088	1.00
139_W	417_N	1.088	1.00
270_K	273_F	1.088	1.00
231_V	241_I	1.087	1.00
25_I	79_F	1.085	1.00
471_R	474_M	1.083	1.00
490_K	494_A	1.079	1.00
428_L	431_C	1.078	1.00
147_F	180_I	1.075	1.00
177_L	226_L	1.074	1.00
575_Q	578_E	1.073	1.00
57_Q	60_R	1.072	1.00
340_F	353_I	1.069	1.00
145_E	221_F	1.069	1.00
335_V	339_T	1.068	1.00
425_K	431_C	1.067	1.00
403_H	448_Q	1.066	1.00
309_L	340_F	1.064	1.00
343_A	347_E	1.063	1.00
185_D	189_D	1.060	1.00
196_Y	374_M	1.060	1.00
429_T	432_R	1.054	1.00
113_I	118_K	1.048	1.00
302_P	306_K	1.048	1.00
200_I	243_L	1.047	1.00
171_D	174_G	1.044	1.00
427_L	432_R	1.043	1.00
525_T	530_I	1.041	1.00
454_I	489_M	1.041	1.00
483_Q	486_L	1.040	1.00
442_L	458_T	1.036	1.00
541_V	575_Q	1.034	1.00
473_C	477_E	1.034	1.00
427_L	430_R	1.034	1.00
559_D	562_T	1.026	1.00
534_F	574_V	1.024	1.00
122_V	320_D	1.023	1.00
100_S	103_C	1.018	1.00
502_L	531_L	1.007	1.00
442_L	454_I	1.007	1.00
467_D	471_R	1.003	1.00
539_N	577_G	1.002	1.00
438_A	461_G	1.001	1.00
99_S	103_C	0.998	1.00
250_I	297_L	0.997	1.00
103_C	106_N	0.993	1.00
511_N	523_S	0.991	1.00
488_F	560_A	0.990	1.00
466_N	469_L	0.990	1.00
139_W	242_M	0.989	1.00
125_A	236_Q	0.989	1.00
295_P	298_N	0.987	1.00
376_Y	379_T	0.987	1.00
144_P	177_L	0.981	1.00
426_R	432_R	0.981	1.00
374_M	379_T	0.980	1.00
42_G	83_Q	0.980	1.00
83_Q	106_N	0.980	1.00
227_F	319_F	0.979	1.00
217_I	315_W	0.979	1.00
62_I	65_T	0.977	1.00
285_Y	288_F	0.977	1.00
446_F	454_I	0.975	1.00
378_F	382_M	0.972	1.00
378_F	448_Q	0.971	1.00
382_M	441_L	0.971	1.00
425_K	428_L	0.970	1.00
283_D	286_D	0.968	1.00
147_F	186_Y	0.966	1.00
243_L	321_I	0.964	1.00
188_E	239_M	0.962	1.00
65_T	68_H	0.960	1.00
382_M	444_F	0.955	1.00
187_L	191_G	0.955	1.00
426_R	430_R	0.952	1.00
215_F	314_Y	0.949	1.00
495_L	558_C	0.948	1.00
440_A	579_F	0.946	1.00
57_Q	87_V	0.945	1.00
306_K	343_A	0.945	1.00
63_A	68_H	0.942	1.00
356_E	422_H	0.940	1.00
309_L	313_L	0.934	1.00
216_S	224_P	0.933	1.00
90_D	94_D	0.932	1.00
56_E	62_I	0.929	1.00
132_E	194_G	0.929	1.00
98_G	102_V	0.927	1.00
384_E	399_R	0.925	1.00
428_L	433_N	0.922	1.00
440_A	537_Q	0.921	1.00
396_M	399_R	0.917	1.00
90_D	96_F	0.916	1.00
142_I	456_Y	0.915	1.00
534_F	544_V	0.915	1.00
215_F	307_Y	0.914	1.00
467_D	470_C	0.913	1.00
20_G	25_I	0.913	1.00
185_D	188_E	0.910	1.00
122_V	126_D	0.910	1.00
22_T	74_E	0.908	1.00
127_T	320_D	0.905	1.00
395_R	398_H	0.901	1.00
288_F	291_T	0.899	1.00
258_Q	261_V	0.898	1.00
270_K	275_I	0.896	1.00
384_E	387_A	0.894	1.00
435_E	438_A	0.894	1.00
342_Q	346_T	0.893	1.00
126_D	129_Q	0.890	1.00
56_E	61_K	0.889	1.00
534_F	582_L	0.889	1.00
170_N	182_D	0.888	1.00
296_K	331_E	0.886	1.00
181_V	226_L	0.882	1.00
299_T	308_L	0.878	1.00
25_I	116_Y	0.876	1.00
480_K	483_Q	0.873	1.00
438_A	485_M	0.873	1.00
41_W	82_L	0.871	1.00
99_S	106_N	0.871	1.00
55_N	60_R	0.870	1.00
35_D	89_T	0.869	1.00
312_A	324_W	0.868	1.00
454_I	458_T	0.867	1.00
150_G	173_F	0.864	1.00
56_E	63_A	0.863	1.00
380_E	384_E	0.863	1.00
305_Q	335_V	0.862	1.00
134_V	352_Y	0.861	1.00
257_W	261_V	0.858	1.00
182_D	185_D	0.856	1.00
338_K	342_Q	0.856	1.00
283_D	287_R	0.856	1.00
471_R	476_W	0.854	1.00
531_L	581_I	0.851	1.00
337_W	340_F	0.850	1.00
397_A	401_N	0.848	1.00
113_I	116_Y	0.847	1.00
102_V	273_F	0.846	1.00
488_F	558_C	0.846	1.00
509_E	566_L	0.845	1.00
392_S	395_R	0.844	1.00
138_V	497_K	0.843	1.00
277_S	284_N	0.842	1.00
211_T	214_Y	0.841	1.00
534_F	580_L	0.838	1.00
420_D	441_L	0.837	1.00
217_I	314_Y	0.836	1.00
428_L	461_G	0.835	1.00
213_D	216_S	0.835	1.00
440_A	535_F	0.833	1.00
38_R	89_T	0.830	1.00
401_N	404_L	0.830	1.00
66_E	72_F	0.828	1.00
180_I	234_L	0.827	1.00
55_N	61_K	0.825	1.00
271_D	301_N	0.823	1.00
193_N	239_M	0.823	1.00
526_L	529_K	0.822	1.00
327_D	423_D	0.821	1.00
75_V	78_P	0.820	1.00
193_N	497_K	0.818	1.00
29_T	34_A	0.817	1.00
327_D	356_E	0.817	1.00
385_Y	537_Q	0.813	1.00
460_I	486_L	0.811	1.00
558_C	561_W	0.810	1.00
177_L	227_F	0.809	1.00
519_F	522_F	0.807	1.00
150_G	179_G	0.806	1.00
312_A	344_V	0.806	1.00
214_Y	307_Y	0.806	1.00
486_L	489_M	0.806	1.00
138_V	446_F	0.803	1.00
32_G	69_D	0.802	1.00
313_L	348_K	0.802	1.00
521_S	524_R	0.802	1.00
312_A	326_L	0.798	1.00
229_T	232_S	0.798	1.00
143_F	198_T	0.797	1.00
30_K	303_E	0.797	1.00
270_K	274_H	0.797	1.00
276_H	286_D	0.796	1.00
115_Y	120_P	0.794	1.00
388_D	392_S	0.794	1.00
391_I	395_R	0.792	1.00
114_H	117_F	0.792	1.00
27_I	39_F	0.790	1.00
249_H	422_H	0.789	1.00
488_F	492_L	0.788	1.00
89_T	95_I	0.787	1.00
38_R	62_I	0.786	1.00
173_F	182_D	0.784	1.00
396_M	402_A	0.783	1.00
181_V	230_L	0.783	1.00
104_P	119_F	0.783	1.00
384_E	388_D	0.781	1.00
485_M	488_F	0.780	1.00
115_Y	119_F	0.778	1.00
375_N	417_N	0.777	1.00
334_H	338_K	0.776	1.00
556_K	562_T	0.776	1.00
495_L	581_I	0.775	1.00
231_V	321_I	0.773	1.00
235_H	241_I	0.771	1.00
150_G	175_G	0.769	1.00
146_R	206_N	0.768	1.00
437_K	440_A	0.768	1.00
429_T	433_N	0.767	1.00
287_R	290_F	0.764	1.00
55_N	62_I	0.763	1.00
504_T	507_H	0.762	1.00
138_V	192_V	0.762	1.00
98_G	101_G	0.761	1.00
214_Y	297_L	0.758	0.99
121_F	225_E	0.758	0.99
139_W	194_G	0.757	0.99
397_A	510_W	0.755	0.99
249_H	327_D	0.754	0.99
560_A	563_E	0.753	0.99
190_L	493_I	0.753	0.99
313_L	344_V	0.752	0.99
470_C	476_W	0.751	0.99
317_R	348_K	0.750	0.99
472_K	478_K	0.750	0.99
468_P	474_M	0.749	0.99
518_D	537_Q	0.748	0.99
20_G	80_R	0.747	0.99
225_E	229_T	0.746	0.99
386_F	444_F	0.744	0.99
466_N	470_C	0.744	0.99
495_L	499_E	0.744	0.99
40_I	85_A	0.741	0.99
354_L	453_C	0.741	0.99
62_I	73_A	0.740	0.99
471_R	475_V	0.740	0.99
38_R	60_R	0.740	0.99
114_H	119_F	0.739	0.99
170_N	173_F	0.739	0.99
399_R	403_H	0.739	0.99
201_F	321_I	0.739	0.99
436_K	439_R	0.739	0.99
125_A	320_D	0.738	0.99
352_Y	372_A	0.738	0.99
83_Q	115_Y	0.738	0.99
392_S	396_M	0.737	0.99
396_M	400_V	0.737	0.99
311_I	314_Y	0.736	0.99
150_G	176_D	0.736	0.99
309_L	339_T	0.736	0.99
367_G	371_H	0.735	0.99
531_L	557_I	0.734	0.99
435_E	485_M	0.733	0.99
430_R	433_N	0.733	0.99
472_K	477_E	0.731	0.99
325_R	423_D	0.730	0.99
509_E	523_S	0.729	0.99
443_A	492_L	0.729	0.99
435_E	484_D	0.729	0.99
338_K	369_E	0.725	0.99
257_W	260_V	0.725	0.99
538_G	542_Q	0.725	0.99
121_F	124_E	0.723	0.99
101_G	105_Y	0.722	0.99
33_D	270_K	0.722	0.99
442_L	485_M	0.721	0.99
182_D	229_T	0.721	0.99
177_L	222_G	0.720	0.99
105_Y	117_F	0.719	0.99
132_E	238_G	0.718	0.99
78_P	116_Y	0.718	0.99
400_V	403_H	0.717	0.99
467_D	473_C	0.717	0.99
178_Q	223_D	0.716	0.99
419_L	445_M	0.716	0.99
379_T	383_I	0.715	0.99
25_I	39_F	0.715	0.99
87_V	95_I	0.714	0.99
276_H	282_D	0.713	0.99
35_D	93_E	0.713	0.99
288_F	296_K	0.712	0.99
344_V	353_I	0.710	0.99
386_F	537_Q	0.710	0.99
519_F	574_V	0.710	0.99
381_P	395_R	0.709	0.99
97_F	101_G	0.709	0.99
398_H	401_N	0.709	0.99
59_M	63_A	0.708	0.99
519_F	524_R	0.708	0.99
393_A	396_M	0.708	0.99
140_Y	459_E	0.708	0.99
490_K	493_I	0.707	0.99
468_P	476_W	0.705	0.99
61_K	75_V	0.704	0.99
192_V	239_M	0.703	0.99
118_K	121_F	0.702	0.99
119_F	122_V	0.701	0.99
124_E	127_T	0.700	0.99
367_G	370_F	0.700	0.99
556_K	580_L	0.698	0.99
426_R	433_N	0.694	0.99
484_D	487_Q	0.693	0.99
327_D	422_H	0.693	0.99
105_Y	213_D	0.690	0.99
113_I	117_F	0.689	0.99
466_N	471_R	0.687	0.99
368_D	371_H	0.686	0.99
21_R	24_H	0.686	0.99
492_L	558_C	0.682	0.99
124_E	129_Q	0.681	0.99
548_E	554_N	0.681	0.99
416_F	452_P	0.681	0.99
523_S	526_L	0.680	0.99
127_T	130_A	0.680	0.99
126_D	236_Q	0.679	0.99
302_P	305_Q	0.678	0.99
56_E	60_R	0.678	0.99
126_D	232_S	0.678	0.99
340_F	344_V	0.673	0.99
399_R	405_M	0.672	0.99
558_C	563_E	0.671	0.99
141_Q	198_T	0.666	0.99
444_F	537_Q	0.663	0.99
61_K	64_A	0.663	0.99
542_Q	573_A	0.663	0.99
394_S	398_H	0.662	0.99
175_G	183_K	0.662	0.99
427_L	433_N	0.662	0.99
123_H	126_D	0.661	0.99
40_I	60_R	0.660	0.99
186_Y	189_D	0.660	0.99
83_Q	113_I	0.660	0.99
57_Q	61_K	0.658	0.99
64_A	73_A	0.656	0.99
563_E	566_L	0.656	0.99
140_Y	190_L	0.654	0.98
118_K	122_V	0.653	0.98
82_L	116_Y	0.652	0.98
463_N	472_K	0.651	0.98
286_D	290_F	0.650	0.98
89_T	94_D	0.650	0.98
316_I	324_W	0.649	0.98
102_V	105_Y	0.648	0.98
518_D	521_S	0.648	0.98
67_M	72_F	0.648	0.98
144_P	200_I	0.648	0.98
559_D	563_E	0.646	0.98
480_K	484_D	0.644	0.98
494_A	497_K	0.643	0.98
375_N	379_T	0.642	0.98
58_P	63_A	0.640	0.98
384_E	389_Q	0.640	0.98
397_A	402_A	0.638	0.98
80_R	118_K	0.638	0.98
290_F	296_K	0.637	0.98
201_F	243_L	0.637	0.98
35_D	92_H	0.636	0.98
41_W	44_P	0.636	0.98
292_A	295_P	0.634	0.98
170_N	174_G	0.634	0.98
520_I	524_R	0.632	0.98
234_L	237_R	0.632	0.98
356_E	423_D	0.632	0.98
131_P	134_V	0.632	0.98
84_Y	88_V	0.630	0.98
120_P	123_H	0.628	0.98
177_L	200_I	0.627	0.98
295_P	299_T	0.625	0.98
232_S	320_D	0.625	0.98
383_I	387_A	0.624	0.98
340_F	343_A	0.624	0.98
485_M	489_M	0.623	0.98
443_A	560_A	0.623	0.98
60_R	87_V	0.623	0.98
34_A	88_V	0.622	0.98
60_R	64_A	0.621	0.98
272_W	275_I	0.621	0.98
62_I	66_E	0.620	0.98
127_T	131_P	0.617	0.98
122_V	129_Q	0.616	0.98
501_T	529_K	0.616	0.98
519_F	544_V	0.616	0.98
572_I	580_L	0.616	0.98
325_R	422_H	0.615	0.98
549_L	554_N	0.614	0.98
374_M	453_C	0.614	0.98
136_S	497_K	0.614	0.98
129_Q	132_E	0.612	0.98
466_N	472_K	0.612	0.98
117_F	121_F	0.612	0.98
188_E	497_K	0.611	0.98
150_G	171_D	0.611	0.98
393_A	401_N	0.610	0.98
108_K	111_E	0.609	0.98
148_A	175_G	0.608	0.98
463_N	478_K	0.608	0.98
185_D	233_Q	0.606	0.98
425_K	432_R	0.605	0.98
56_E	59_M	0.603	0.97
522_F	525_T	0.603	0.97
443_A	447_A	0.602	0.97
62_I	68_H	0.602	0.97
210_D	251_G	0.602	0.97
63_A	66_E	0.601	0.97
132_E	135_K	0.599	0.97
574_V	580_L	0.597	0.97
197_L	227_F	0.596	0.97
231_V	319_F	0.596	0.97
430_R	463_N	0.595	0.97
421_S	453_C	0.595	0.97
348_K	351_V	0.594	0.97
218_D	221_F	0.593	0.97
41_W	61_K	0.592	0.97
325_R	356_E	0.592	0.97
33_D	91_D	0.592	0.97
31_K	34_A	0.592	0.97
249_H	423_D	0.592	0.97
316_I	347_E	0.591	0.97
177_L	230_L	0.591	0.97
116_Y	119_F	0.591	0.97
425_K	433_N	0.591	0.97
452_P	496_R	0.589	0.97
246_V	249_H	0.587	0.97
469_L	474_M	0.586	0.97
473_C	478_K	0.585	0.97
388_D	399_R	0.585	0.97
307_Y	311_I	0.584	0.97
180_I	195_I	0.584	0.97
438_A	442_L	0.583	0.97
136_S	505_E	0.582	0.97
282_D	285_Y	0.581	0.97
556_K	561_W	0.580	0.97
444_F	448_Q	0.580	0.97
551_I	568_H	0.580	0.97
98_G	103_C	0.579	0.97
518_D	524_R	0.579	0.97
252_S	293_D	0.578	0.97
249_H	356_E	0.577	0.97
505_E	526_L	0.577	0.97
447_A	535_F	0.577	0.97
489_M	493_I	0.576	0.97
20_G	23_V	0.575	0.97
181_V	185_D	0.574	0.97
35_D	90_D	0.574	0.97
108_K	219_P	0.573	0.97
344_V	348_K	0.573	0.97
98_G	105_Y	0.573	0.97
56_E	87_V	0.572	0.97
173_F	176_D	0.571	0.96
299_T	333_D	0.569	0.96
85_A	96_F	0.569	0.96
247_F	326_L	0.566	0.96
186_Y	460_I	0.564	0.96
58_P	62_I	0.563	0.96
102_V	112_T	0.562	0.96
378_F	381_P	0.561	0.96
427_L	441_L	0.561	0.96
192_V	459_E	0.560	0.96
89_T	92_H	0.560	0.96
97_F	100_S	0.560	0.96
397_A	403_H	0.560	0.96
122_V	228_R	0.559	0.96
462_L	474_M	0.559	0.96
329_A	355_G	0.559	0.96
554_N	563_E	0.558	0.96
217_I	224_P	0.558	0.96
549_L	552_D	0.558	0.96
175_G	179_G	0.558	0.96
399_R	404_L	0.557	0.96
59_M	62_I	0.557	0.96
517_N	542_Q	0.555	0.96
148_A	182_D	0.555	0.96
289_A	292_A	0.553	0.96
332_V	337_W	0.553	0.96
147_F	187_L	0.552	0.96
469_L	476_W	0.551	0.96
512_L	521_S	0.550	0.96
435_E	461_G	0.547	0.96
105_Y	115_Y	0.546	0.95
74_E	77_P	0.546	0.95
189_D	487_Q	0.545	0.95
24_H	76_V	0.544	0.95
39_F	86_F	0.544	0.95
55_N	63_A	0.544	0.95
194_G	352_Y	0.544	0.95
405_M	409_K	0.543	0.95
102_V	106_N	0.542	0.95
228_R	314_Y	0.542	0.95
128_F	131_P	0.541	0.95
518_D	522_F	0.540	0.95
80_R	117_F	0.540	0.95
109_T	174_G	0.540	0.95
231_V	235_H	0.540	0.95
519_F	542_Q	0.539	0.95
90_D	93_E	0.538	0.95
400_V	404_L	0.538	0.95
249_H	325_R	0.536	0.95
574_V	577_G	0.536	0.95
434_D	437_K	0.536	0.95
61_K	65_T	0.535	0.95
22_T	76_V	0.535	0.95
443_A	535_F	0.533	0.95
109_T	112_T	0.532	0.95
184_L	188_E	0.532	0.95
560_A	565_P	0.531	0.95
432_R	437_K	0.530	0.95
517_N	521_S	0.530	0.95
410_Q	414_V	0.530	0.95
389_Q	392_S	0.528	0.95
285_Y	289_A	0.527	0.95
554_N	561_W	0.527	0.95
568_H	571_V	0.526	0.94
188_E	238_G	0.526	0.94
374_M	378_F	0.526	0.94
27_I	75_V	0.524	0.94
297_L	308_L	0.523	0.94
244_D	327_D	0.523	0.94
113_I	119_F	0.523	0.94
245_A	324_W	0.520	0.94
564_Q	567_Q	0.519	0.94
574_V	578_E	0.518	0.94
139_W	354_L	0.517	0.94
375_N	415_M	0.517	0.94
305_Q	309_L	0.516	0.94
132_E	136_S	0.516	0.94
441_L	444_F	0.516	0.94
123_H	232_S	0.514	0.94
394_S	397_A	0.513	0.94
39_F	75_V	0.513	0.94
336_F	341_R	0.513	0.94
326_L	353_I	0.512	0.94
212_L	251_G	0.512	0.94
381_P	384_E	0.512	0.94
105_Y	219_P	0.511	0.94
508_L	511_N	0.510	0.94
106_N	114_H	0.508	0.93
101_G	104_P	0.506	0.93
495_L	502_L	0.506	0.93
308_L	336_F	0.505	0.93
522_F	526_L	0.505	0.93
209_Y	422_H	0.504	0.93
114_H	120_P	0.503	0.93
443_A	581_I	0.503	0.93
261_V	270_K	0.503	0.93
517_N	524_R	0.502	0.93
540_V	576_P	0.502	0.93
192_V	493_I	0.501	0.93
289_A	331_E	0.501	0.93
404_L	409_K	0.500	0.93
379_T	424_T	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ea9C	2	0.9762	100	0.162	Contact Map
1wzlA	2	0.9745	100	0.169	Contact Map
1j0hA	2	0.9847	100	0.17	Contact Map
4aeeA	1	0.9184	100	0.209	Contact Map
1ji1A	1	0.9524	100	0.218	Contact Map
3wdhA	1	0.9303	100	0.262	Contact Map
2e8yA	1	0.9405	100	0.264	Contact Map
4aefA	1	0.8435	100	0.264	Contact Map
2wanA	1	0.915	100	0.272	Contact Map
1bf2A	1	0.9252	100	0.274	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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