GREMLIN Database
YVCN - Uncharacterized acetyltransferase YvcN
UniProt: O06977 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 254 (243)
Sequences: 1724 (1285)
Seq/√Len: 82.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
52_K57_E4.2471.00
30_F78_L3.9031.00
154_K166_L3.7241.00
11_C34_M3.4521.00
61_R73_D3.0221.00
44_A49_E2.9921.00
92_I114_W2.8361.00
152_R166_L2.8091.00
88_H116_S2.7851.00
54_T57_E2.7591.00
166_L175_I2.7221.00
38_F62_L2.6171.00
238_S244_G2.5931.00
96_V128_F2.5501.00
210_A249_L2.5111.00
240_I248_K2.4911.00
120_G138_P2.4231.00
70_L193_K2.4181.00
60_R65_D2.3911.00
60_R64_K2.3791.00
53_I58_L2.2561.00
247_E251_T2.2511.00
78_L126_I2.1501.00
152_R173_W2.1481.00
28_P136_P2.1011.00
116_S121_D2.0691.00
31_L133_A1.9951.00
138_P144_V1.9921.00
74_L81_V1.9771.00
59_W63_L1.9351.00
23_S26_D1.9311.00
89_V113_V1.8811.00
78_L124_V1.8601.00
55_K80_F1.8511.00
79_Y89_V1.8441.00
226_F248_K1.8011.00
112_A123_L1.7961.00
31_L124_V1.7861.00
8_L81_V1.7831.00
17_W26_D1.7831.00
44_A67_H1.7681.00
92_I112_A1.7631.00
219_M252_H1.7631.00
31_L136_P1.7521.00
194_D198_S1.6861.00
24_F28_P1.6841.00
90_K183_E1.6791.00
91_L189_L1.6171.00
29_L33_A1.5931.00
15_I81_V1.5521.00
156_E164_V1.5170.99
51_Y197_H1.5160.99
10_D64_K1.5140.99
114_W121_D1.4910.99
248_K252_H1.4640.99
41_E68_G1.4510.99
195_I199_H1.4490.99
141_G155_K1.4490.99
41_E67_H1.4410.99
58_L62_L1.4340.99
8_L84_E1.4290.99
164_V178_A1.4030.99
59_W77_F1.3990.99
45_V51_Y1.3950.99
79_Y91_L1.3710.99
128_F177_Y1.3710.99
32_K36_Y1.3650.99
32_K135_Q1.3620.99
12_F81_V1.3580.99
111_A189_L1.3520.99
241_G244_G1.3310.99
224_R239_D1.3130.98
19_K26_D1.3050.98
240_I245_F1.3000.98
214_T217_G1.2930.98
17_W20_D1.2690.98
166_L173_W1.2560.98
24_F117_A1.2440.98
20_D26_D1.2400.98
34_M126_I1.2380.98
120_G140_S1.2380.98
79_Y113_V1.2370.98
58_L76_G1.2250.98
20_D85_A1.2230.98
28_P31_L1.2130.97
7_F10_D1.2020.97
34_M74_L1.1950.97
153_I163_Y1.1940.97
24_F122_Y1.1920.97
193_K197_H1.1910.97
30_F126_I1.1860.97
17_W29_L1.1850.97
153_I165_L1.1830.97
79_Y83_R1.1810.97
30_F81_V1.1810.97
43_R208_L1.1560.96
59_W64_K1.1550.96
185_D188_D1.1500.96
230_E233_G1.1420.96
109_T196_I1.1340.96
90_K114_W1.1280.96
207_S222_S1.1220.96
26_D87_F1.1220.96
219_M228_I1.1150.96
38_F41_E1.1130.96
15_I37_R1.1060.95
199_H205_N1.1010.95
81_V85_A1.0890.95
145_Q150_S1.0850.95
207_S223_E1.0590.94
27_L115_L1.0560.94
7_F59_W1.0430.94
70_L196_I1.0240.93
51_Y61_R1.0210.93
164_V175_I1.0200.93
226_F252_H1.0140.93
70_L197_H1.0130.93
28_P135_Q1.0060.93
108_G184_S1.0010.92
83_R91_L0.9960.92
108_G180_T0.9840.92
46_L208_L0.9810.92
244_G248_K0.9800.92
61_R67_H0.9700.91
93_R184_S0.9680.91
40_F204_F0.9580.91
58_L77_F0.9540.90
184_S189_L0.9390.90
228_I252_H0.9350.90
146_S149_G0.9270.89
31_L146_S0.9250.89
67_H73_D0.9210.89
135_Q147_P0.9190.89
22_V87_F0.9190.89
228_I236_Q0.9170.89
90_K116_S0.9070.88
121_D181_L0.9030.88
139_L179_F0.9030.88
78_L81_V0.9020.88
80_F84_E0.9010.88
137_I169_K0.8990.88
216_S230_E0.8930.87
31_L126_I0.8890.87
134_L148_V0.8850.87
78_L113_V0.8800.87
90_K121_D0.8760.86
81_V84_E0.8750.86
22_V26_D0.8740.86
117_A120_G0.8700.86
217_G228_I0.8560.85
140_S163_Y0.8550.85
45_V48_K0.8500.85
137_I153_I0.8480.84
192_M196_I0.8450.84
95_T194_D0.8390.84
225_H237_K0.8300.83
92_I181_L0.8290.83
62_L74_L0.8260.83
9_K19_K0.8240.83
17_W33_A0.8240.83
112_A179_F0.8220.83
14_K38_F0.8220.83
7_F84_E0.8190.82
16_G37_R0.8180.82
220_V227_T0.8170.82
9_K13_Q0.8160.82
93_R192_M0.8140.82
31_L78_L0.8140.82
132_L146_S0.8110.82
142_E163_Y0.8100.82
96_V204_F0.7930.80
70_L85_A0.7890.80
108_G192_M0.7880.80
184_S188_D0.7860.80
199_H202_S0.7840.79
51_Y193_K0.7810.79
221_M226_F0.7780.79
129_G204_F0.7750.79
144_V148_V0.7710.78
225_H239_D0.7690.78
100_D103_G0.7690.78
34_M81_V0.7670.78
36_Y215_P0.7600.77
31_L35_A0.7590.77
43_R61_R0.7560.77
12_F33_A0.7560.77
71_C110_H0.7460.76
137_I144_V0.7430.76
193_K196_I0.7430.76
87_F115_L0.7420.76
77_F81_V0.7390.75
228_I235_I0.7370.75
211_S220_V0.7350.75
95_T193_K0.7350.75
70_L109_T0.7340.75
165_L177_Y0.7320.75
12_F34_M0.7300.74
120_G221_M0.7300.74
7_F64_K0.7250.74
75_N126_I0.7180.73
169_K172_G0.7130.73
18_E60_R0.7110.73
66_Q155_K0.7100.72
55_K59_W0.7060.72
41_E210_A0.7060.72
107_E191_N0.7060.72
74_L217_G0.7040.72
11_C81_V0.7040.72
105_A185_D0.7000.71
167_M176_G0.6980.71
53_I65_D0.6970.71
242_P251_T0.6970.71
97_Y164_V0.6920.70
219_M226_F0.6880.70
163_Y181_L0.6880.70
109_T128_F0.6840.70
94_G97_Y0.6840.70
134_L146_S0.6820.69
226_F237_K0.6820.69
91_L111_A0.6790.69
139_L163_Y0.6790.69
53_I189_L0.6710.68
238_S248_K0.6700.68
19_K29_L0.6670.68
15_I185_D0.6660.68
14_K41_E0.6640.67
25_G56_E0.6640.67
38_F74_L0.6630.67
123_L177_Y0.6600.67
41_E61_R0.6600.67
51_Y73_D0.6600.67
230_E234_N0.6590.67
238_S252_H0.6590.67
93_R108_G0.6560.66
155_K163_Y0.6520.66
32_K147_P0.6520.66
93_R189_L0.6500.66
99_G176_G0.6480.65
149_G211_S0.6460.65
133_A151_F0.6450.65
203_P206_K0.6450.65
72_Y196_I0.6420.65
151_F176_G0.6410.65
59_W80_F0.6400.64
15_I33_A0.6400.64
235_I239_D0.6390.64
130_I209_L0.6380.64
213_L218_R0.6370.64
12_F20_D0.6360.64
109_T192_M0.6350.64
36_Y213_L0.6320.64
53_I70_L0.6300.63
61_R193_K0.6260.63
39_P66_Q0.6250.63
20_D29_L0.6240.63
209_L222_S0.6220.62
72_Y204_F0.6210.62
38_F63_L0.6180.62
43_R73_D0.6180.62
138_P143_T0.6170.62
141_G163_Y0.6160.62
94_G177_Y0.6150.61
11_C188_D0.6120.61
72_Y93_R0.6090.61
226_F241_G0.6080.61
56_E59_W0.6080.61
131_N167_M0.6080.61
144_V173_W0.6060.60
65_D157_E0.6020.60
109_T129_G0.6000.60
62_L77_F0.5990.59
62_L81_V0.5990.59
43_R210_A0.5990.59
38_F224_R0.5980.59
95_T188_D0.5980.59
228_I238_S0.5970.59
223_E226_F0.5970.59
53_I193_K0.5970.59
87_F90_K0.5960.59
69_G73_D0.5950.59
27_L39_P0.5940.59
97_Y178_A0.5940.59
151_F165_L0.5940.59
202_S205_N0.5910.58
210_A245_F0.5900.58
27_L87_F0.5890.58
43_R67_H0.5820.57
45_V70_L0.5780.57
224_R228_I0.5780.57
14_K61_R0.5780.57
14_K37_R0.5760.56
88_H236_Q0.5760.56
140_S143_T0.5760.56
234_N240_I0.5740.56
44_A61_R0.5730.56
45_V205_N0.5730.56
96_V129_G0.5730.56
165_L223_E0.5710.56
66_Q156_E0.5700.56
42_N205_N0.5700.56
156_E162_S0.5700.56
194_D197_H0.5690.56
20_D23_S0.5690.56
93_R193_K0.5680.55
74_L78_L0.5660.55
163_Y179_F0.5610.54
144_V151_F0.5590.54
122_Y138_P0.5570.54
218_R229_Y0.5560.54
201_K235_I0.5560.54
63_L77_F0.5550.54
237_K240_I0.5540.54
220_V229_Y0.5520.53
50_N198_S0.5490.53
31_L122_Y0.5480.53
95_T104_W0.5450.52
58_L73_D0.5450.52
124_V131_N0.5440.52
247_E250_N0.5420.52
17_W23_S0.5400.52
95_T108_G0.5400.52
13_Q18_E0.5400.52
227_T237_K0.5390.52
216_S231_N0.5390.52
136_P221_M0.5360.51
41_E87_F0.5360.51
25_G138_P0.5360.51
19_K38_F0.5340.51
108_G182_E0.5340.51
70_L205_N0.5280.50
198_S205_N0.5280.50
38_F115_L0.5270.50
203_P222_S0.5260.50
135_Q146_S0.5260.50
46_L98_A0.5250.50
78_L189_L0.5250.50
214_T219_M0.5250.50
45_V170_G0.5240.50
91_L112_A0.5190.49
71_C127_G0.5170.49
243_S247_E0.5160.49
139_L170_G0.5160.49
174_Q238_S0.5160.49
134_L147_P0.5160.49
83_R226_F0.5120.48
99_G174_Q0.5110.48
191_N195_I0.5110.48
44_A51_Y0.5110.48
69_G110_H0.5110.48
148_V151_F0.5100.48
48_K205_N0.5070.47
51_Y190_D0.5070.47
119_N122_Y0.5060.47
197_H205_N0.5050.47
239_D242_P0.5040.47
145_Q148_V0.5040.47
221_M240_I0.5030.47
198_S204_F0.5030.47
208_L212_K0.5030.47
133_A149_G0.5020.47
212_K219_M0.5010.47
111_A196_I0.5010.47
75_N189_L0.5010.47
147_P151_F0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1w4tA 1 0.9921 100 0.072 Contact Map
4nv8A 2 0.9685 100 0.078 Contact Map
3lnbA 1 0.9843 100 0.087 Contact Map
4guzA 2 0.9882 100 0.087 Contact Map
1w5rA 2 0.9685 100 0.088 Contact Map
3d9wA 2 0.9882 100 0.091 Contact Map
4dmoA 1 0.9803 100 0.091 Contact Map
1e2tA 5 0.9724 100 0.102 Contact Map
4c5pA 1 0.9606 100 0.102 Contact Map
2ijaA 1 0.9764 100 0.103 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0092 seconds.