YVCN - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YVCN - Uncharacterized acetyltransferase YvcN

UniProt:	O06977	Sequences: MIKMSDFLKDCFQKIGWEKDHVSFGDLPLFLKAMAYRFPFENRAVLAKENYKITKEELWRRLLKDQHGGLCYDLNGFLYFVLREAGFHVKLIRGTVYAGDQEGWALEGTHAAVWLSAENGDYLVDIGFGINLALQPIPLSGETVQSPVGSFRIKKEETEKGSYVLLMDKGEGWQIGYAFTLEESDLGDLDNMKDIIHSHEKSPFNKSLLASKLTPSGRMVMSERHFTIYENGGNIQKSDIGPSGFEEKLNTHFL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	254 (243)
Sequences:	1724 (1285)
Seq/√Len:	82.4

ECOLI - NHOA
BACSU - YVCN

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
52_K	57_E	4.247	1.00
30_F	78_L	3.903	1.00
154_K	166_L	3.724	1.00
11_C	34_M	3.452	1.00
61_R	73_D	3.022	1.00
44_A	49_E	2.992	1.00
92_I	114_W	2.836	1.00
152_R	166_L	2.809	1.00
88_H	116_S	2.785	1.00
54_T	57_E	2.759	1.00
166_L	175_I	2.722	1.00
38_F	62_L	2.617	1.00
238_S	244_G	2.593	1.00
96_V	128_F	2.550	1.00
210_A	249_L	2.511	1.00
240_I	248_K	2.491	1.00
120_G	138_P	2.423	1.00
70_L	193_K	2.418	1.00
60_R	65_D	2.391	1.00
60_R	64_K	2.379	1.00
53_I	58_L	2.256	1.00
247_E	251_T	2.251	1.00
78_L	126_I	2.150	1.00
152_R	173_W	2.148	1.00
28_P	136_P	2.101	1.00
116_S	121_D	2.069	1.00
31_L	133_A	1.995	1.00
138_P	144_V	1.992	1.00
74_L	81_V	1.977	1.00
59_W	63_L	1.935	1.00
23_S	26_D	1.931	1.00
89_V	113_V	1.881	1.00
78_L	124_V	1.860	1.00
55_K	80_F	1.851	1.00
79_Y	89_V	1.844	1.00
226_F	248_K	1.801	1.00
112_A	123_L	1.796	1.00
31_L	124_V	1.786	1.00
8_L	81_V	1.783	1.00
17_W	26_D	1.783	1.00
44_A	67_H	1.768	1.00
92_I	112_A	1.763	1.00
219_M	252_H	1.763	1.00
31_L	136_P	1.752	1.00
194_D	198_S	1.686	1.00
24_F	28_P	1.684	1.00
90_K	183_E	1.679	1.00
91_L	189_L	1.617	1.00
29_L	33_A	1.593	1.00
15_I	81_V	1.552	1.00
156_E	164_V	1.517	0.99
51_Y	197_H	1.516	0.99
10_D	64_K	1.514	0.99
114_W	121_D	1.491	0.99
248_K	252_H	1.464	0.99
41_E	68_G	1.451	0.99
195_I	199_H	1.449	0.99
141_G	155_K	1.449	0.99
41_E	67_H	1.441	0.99
58_L	62_L	1.434	0.99
8_L	84_E	1.429	0.99
164_V	178_A	1.403	0.99
59_W	77_F	1.399	0.99
45_V	51_Y	1.395	0.99
79_Y	91_L	1.371	0.99
128_F	177_Y	1.371	0.99
32_K	36_Y	1.365	0.99
32_K	135_Q	1.362	0.99
12_F	81_V	1.358	0.99
111_A	189_L	1.352	0.99
241_G	244_G	1.331	0.99
224_R	239_D	1.313	0.98
19_K	26_D	1.305	0.98
240_I	245_F	1.300	0.98
214_T	217_G	1.293	0.98
17_W	20_D	1.269	0.98
166_L	173_W	1.256	0.98
24_F	117_A	1.244	0.98
20_D	26_D	1.240	0.98
34_M	126_I	1.238	0.98
120_G	140_S	1.238	0.98
79_Y	113_V	1.237	0.98
58_L	76_G	1.225	0.98
20_D	85_A	1.223	0.98
28_P	31_L	1.213	0.97
7_F	10_D	1.202	0.97
34_M	74_L	1.195	0.97
153_I	163_Y	1.194	0.97
24_F	122_Y	1.192	0.97
193_K	197_H	1.191	0.97
30_F	126_I	1.186	0.97
17_W	29_L	1.185	0.97
153_I	165_L	1.183	0.97
79_Y	83_R	1.181	0.97
30_F	81_V	1.181	0.97
43_R	208_L	1.156	0.96
59_W	64_K	1.155	0.96
185_D	188_D	1.150	0.96
230_E	233_G	1.142	0.96
109_T	196_I	1.134	0.96
90_K	114_W	1.128	0.96
207_S	222_S	1.122	0.96
26_D	87_F	1.122	0.96
219_M	228_I	1.115	0.96
38_F	41_E	1.113	0.96
15_I	37_R	1.106	0.95
199_H	205_N	1.101	0.95
81_V	85_A	1.089	0.95
145_Q	150_S	1.085	0.95
207_S	223_E	1.059	0.94
27_L	115_L	1.056	0.94
7_F	59_W	1.043	0.94
70_L	196_I	1.024	0.93
51_Y	61_R	1.021	0.93
164_V	175_I	1.020	0.93
226_F	252_H	1.014	0.93
70_L	197_H	1.013	0.93
28_P	135_Q	1.006	0.93
108_G	184_S	1.001	0.92
83_R	91_L	0.996	0.92
108_G	180_T	0.984	0.92
46_L	208_L	0.981	0.92
244_G	248_K	0.980	0.92
61_R	67_H	0.970	0.91
93_R	184_S	0.968	0.91
40_F	204_F	0.958	0.91
58_L	77_F	0.954	0.90
184_S	189_L	0.939	0.90
228_I	252_H	0.935	0.90
146_S	149_G	0.927	0.89
31_L	146_S	0.925	0.89
67_H	73_D	0.921	0.89
135_Q	147_P	0.919	0.89
22_V	87_F	0.919	0.89
228_I	236_Q	0.917	0.89
90_K	116_S	0.907	0.88
121_D	181_L	0.903	0.88
139_L	179_F	0.903	0.88
78_L	81_V	0.902	0.88
80_F	84_E	0.901	0.88
137_I	169_K	0.899	0.88
216_S	230_E	0.893	0.87
31_L	126_I	0.889	0.87
134_L	148_V	0.885	0.87
78_L	113_V	0.880	0.87
90_K	121_D	0.876	0.86
81_V	84_E	0.875	0.86
22_V	26_D	0.874	0.86
117_A	120_G	0.870	0.86
217_G	228_I	0.856	0.85
140_S	163_Y	0.855	0.85
45_V	48_K	0.850	0.85
137_I	153_I	0.848	0.84
192_M	196_I	0.845	0.84
95_T	194_D	0.839	0.84
225_H	237_K	0.830	0.83
92_I	181_L	0.829	0.83
62_L	74_L	0.826	0.83
9_K	19_K	0.824	0.83
17_W	33_A	0.824	0.83
112_A	179_F	0.822	0.83
14_K	38_F	0.822	0.83
7_F	84_E	0.819	0.82
16_G	37_R	0.818	0.82
220_V	227_T	0.817	0.82
9_K	13_Q	0.816	0.82
93_R	192_M	0.814	0.82
31_L	78_L	0.814	0.82
132_L	146_S	0.811	0.82
142_E	163_Y	0.810	0.82
96_V	204_F	0.793	0.80
70_L	85_A	0.789	0.80
108_G	192_M	0.788	0.80
184_S	188_D	0.786	0.80
199_H	202_S	0.784	0.79
51_Y	193_K	0.781	0.79
221_M	226_F	0.778	0.79
129_G	204_F	0.775	0.79
144_V	148_V	0.771	0.78
225_H	239_D	0.769	0.78
100_D	103_G	0.769	0.78
34_M	81_V	0.767	0.78
36_Y	215_P	0.760	0.77
31_L	35_A	0.759	0.77
43_R	61_R	0.756	0.77
12_F	33_A	0.756	0.77
71_C	110_H	0.746	0.76
137_I	144_V	0.743	0.76
193_K	196_I	0.743	0.76
87_F	115_L	0.742	0.76
77_F	81_V	0.739	0.75
228_I	235_I	0.737	0.75
211_S	220_V	0.735	0.75
95_T	193_K	0.735	0.75
70_L	109_T	0.734	0.75
165_L	177_Y	0.732	0.75
12_F	34_M	0.730	0.74
120_G	221_M	0.730	0.74
7_F	64_K	0.725	0.74
75_N	126_I	0.718	0.73
169_K	172_G	0.713	0.73
18_E	60_R	0.711	0.73
66_Q	155_K	0.710	0.72
55_K	59_W	0.706	0.72
41_E	210_A	0.706	0.72
107_E	191_N	0.706	0.72
74_L	217_G	0.704	0.72
11_C	81_V	0.704	0.72
105_A	185_D	0.700	0.71
167_M	176_G	0.698	0.71
53_I	65_D	0.697	0.71
242_P	251_T	0.697	0.71
97_Y	164_V	0.692	0.70
219_M	226_F	0.688	0.70
163_Y	181_L	0.688	0.70
109_T	128_F	0.684	0.70
94_G	97_Y	0.684	0.70
134_L	146_S	0.682	0.69
226_F	237_K	0.682	0.69
91_L	111_A	0.679	0.69
139_L	163_Y	0.679	0.69
53_I	189_L	0.671	0.68
238_S	248_K	0.670	0.68
19_K	29_L	0.667	0.68
15_I	185_D	0.666	0.68
14_K	41_E	0.664	0.67
25_G	56_E	0.664	0.67
38_F	74_L	0.663	0.67
123_L	177_Y	0.660	0.67
41_E	61_R	0.660	0.67
51_Y	73_D	0.660	0.67
230_E	234_N	0.659	0.67
238_S	252_H	0.659	0.67
93_R	108_G	0.656	0.66
155_K	163_Y	0.652	0.66
32_K	147_P	0.652	0.66
93_R	189_L	0.650	0.66
99_G	176_G	0.648	0.65
149_G	211_S	0.646	0.65
133_A	151_F	0.645	0.65
203_P	206_K	0.645	0.65
72_Y	196_I	0.642	0.65
151_F	176_G	0.641	0.65
59_W	80_F	0.640	0.64
15_I	33_A	0.640	0.64
235_I	239_D	0.639	0.64
130_I	209_L	0.638	0.64
213_L	218_R	0.637	0.64
12_F	20_D	0.636	0.64
109_T	192_M	0.635	0.64
36_Y	213_L	0.632	0.64
53_I	70_L	0.630	0.63
61_R	193_K	0.626	0.63
39_P	66_Q	0.625	0.63
20_D	29_L	0.624	0.63
209_L	222_S	0.622	0.62
72_Y	204_F	0.621	0.62
38_F	63_L	0.618	0.62
43_R	73_D	0.618	0.62
138_P	143_T	0.617	0.62
141_G	163_Y	0.616	0.62
94_G	177_Y	0.615	0.61
11_C	188_D	0.612	0.61
72_Y	93_R	0.609	0.61
226_F	241_G	0.608	0.61
56_E	59_W	0.608	0.61
131_N	167_M	0.608	0.61
144_V	173_W	0.606	0.60
65_D	157_E	0.602	0.60
109_T	129_G	0.600	0.60
62_L	77_F	0.599	0.59
62_L	81_V	0.599	0.59
43_R	210_A	0.599	0.59
38_F	224_R	0.598	0.59
95_T	188_D	0.598	0.59
228_I	238_S	0.597	0.59
223_E	226_F	0.597	0.59
53_I	193_K	0.597	0.59
87_F	90_K	0.596	0.59
69_G	73_D	0.595	0.59
27_L	39_P	0.594	0.59
97_Y	178_A	0.594	0.59
151_F	165_L	0.594	0.59
202_S	205_N	0.591	0.58
210_A	245_F	0.590	0.58
27_L	87_F	0.589	0.58
43_R	67_H	0.582	0.57
45_V	70_L	0.578	0.57
224_R	228_I	0.578	0.57
14_K	61_R	0.578	0.57
14_K	37_R	0.576	0.56
88_H	236_Q	0.576	0.56
140_S	143_T	0.576	0.56
234_N	240_I	0.574	0.56
44_A	61_R	0.573	0.56
45_V	205_N	0.573	0.56
96_V	129_G	0.573	0.56
165_L	223_E	0.571	0.56
66_Q	156_E	0.570	0.56
42_N	205_N	0.570	0.56
156_E	162_S	0.570	0.56
194_D	197_H	0.569	0.56
20_D	23_S	0.569	0.56
93_R	193_K	0.568	0.55
74_L	78_L	0.566	0.55
163_Y	179_F	0.561	0.54
144_V	151_F	0.559	0.54
122_Y	138_P	0.557	0.54
218_R	229_Y	0.556	0.54
201_K	235_I	0.556	0.54
63_L	77_F	0.555	0.54
237_K	240_I	0.554	0.54
220_V	229_Y	0.552	0.53
50_N	198_S	0.549	0.53
31_L	122_Y	0.548	0.53
95_T	104_W	0.545	0.52
58_L	73_D	0.545	0.52
124_V	131_N	0.544	0.52
247_E	250_N	0.542	0.52
17_W	23_S	0.540	0.52
95_T	108_G	0.540	0.52
13_Q	18_E	0.540	0.52
227_T	237_K	0.539	0.52
216_S	231_N	0.539	0.52
136_P	221_M	0.536	0.51
41_E	87_F	0.536	0.51
25_G	138_P	0.536	0.51
19_K	38_F	0.534	0.51
108_G	182_E	0.534	0.51
70_L	205_N	0.528	0.50
198_S	205_N	0.528	0.50
38_F	115_L	0.527	0.50
203_P	222_S	0.526	0.50
135_Q	146_S	0.526	0.50
46_L	98_A	0.525	0.50
78_L	189_L	0.525	0.50
214_T	219_M	0.525	0.50
45_V	170_G	0.524	0.50
91_L	112_A	0.519	0.49
71_C	127_G	0.517	0.49
243_S	247_E	0.516	0.49
139_L	170_G	0.516	0.49
174_Q	238_S	0.516	0.49
134_L	147_P	0.516	0.49
83_R	226_F	0.512	0.48
99_G	174_Q	0.511	0.48
191_N	195_I	0.511	0.48
44_A	51_Y	0.511	0.48
69_G	110_H	0.511	0.48
148_V	151_F	0.510	0.48
48_K	205_N	0.507	0.47
51_Y	190_D	0.507	0.47
119_N	122_Y	0.506	0.47
197_H	205_N	0.505	0.47
239_D	242_P	0.504	0.47
145_Q	148_V	0.504	0.47
221_M	240_I	0.503	0.47
198_S	204_F	0.503	0.47
208_L	212_K	0.503	0.47
133_A	149_G	0.502	0.47
212_K	219_M	0.501	0.47
111_A	196_I	0.501	0.47
75_N	189_L	0.501	0.47
147_P	151_F	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1w4tA	1	0.9921	100	0.072	Contact Map
4nv8A	2	0.9685	100	0.078	Contact Map
3lnbA	1	0.9843	100	0.087	Contact Map
4guzA	2	0.9882	100	0.087	Contact Map
1w5rA	2	0.9685	100	0.088	Contact Map
3d9wA	2	0.9882	100	0.091	Contact Map
4dmoA	1	0.9803	100	0.091	Contact Map
1e2tA	5	0.9724	100	0.102	Contact Map
4c5pA	1	0.9606	100	0.102	Contact Map
2ijaA	1	0.9764	100	0.103	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0087 seconds.