YITO - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YITO - Uncharacterized protein YitO

UniProt:	O06750	Sequences: MLENIKQTITRWDERNPWTNVYGLARSIIALSSLLTLLINHPSLIMKPASGISSYPACKMNLSLFCLGENNYMMLNLFRWVCIAILVLVVIGWRPRITGVLHWYVSYSLQSSLIVIDGGEQAAAVMTFLLLPITLTDPRKWHWSTRPIEGKRTLGKITAFISYFVIRIQVAVLYFHSTVAKLSQQEWVDGTAVYYFAQEKTIGFNGFFQALTKPIVTSPFVVIPTWGTLLVQIVIFAALFAPKKHWRLILIIAVFMHEIFAVMLGLISFSIIMAGILILYLTPIDSTIQFTYIRRLLWNKKHKKGEVSV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	309 (270)
Sequences:	982 (761)
Seq/√Len:	46.3

BACSU - YITO SDPB
HALSA - Q9HR62

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
91_I	143_W	4.822	1.00
30_A	90_V	4.239	1.00
88_L	98_T	4.027	1.00
122_A	173_L	3.800	1.00
34_L	90_V	3.563	1.00
33_S	102_H	3.500	1.00
174_Y	257_H	3.435	1.00
100_V	131_L	3.189	1.00
143_W	146_R	3.170	1.00
88_L	91_I	3.113	1.00
192_A	196_F	3.111	1.00
253_A	277_L	2.911	1.00
85_I	101_L	2.739	1.00
173_L	273_M	2.657	1.00
34_L	83_I	2.627	1.00
87_V	91_I	2.533	1.00
95_P	142_H	2.481	1.00
31_L	90_V	2.438	1.00
164_F	167_R	2.354	1.00
128_F	131_L	2.248	1.00
136_T	144_S	2.223	1.00
95_P	136_T	2.212	1.00
89_V	102_H	2.210	1.00
256_M	260_F	2.169	1.00
288_I	292_Y	2.158	1.00
178_T	233_I	2.153	1.00
95_P	144_S	2.092	1.00
194_Y	198_Q	2.091	1.00
94_R	147_P	1.984	0.99
190_G	196_F	1.975	0.99
182_L	229_L	1.969	0.99
102_H	127_T	1.931	0.99
118_G	269_F	1.846	0.99
256_M	270_S	1.842	0.99
235_I	253_A	1.809	0.99
85_I	98_T	1.806	0.99
34_L	87_V	1.788	0.99
103_W	131_L	1.779	0.99
143_W	147_P	1.749	0.98
241_A	245_H	1.743	0.98
125_V	129_L	1.739	0.98
19_T	23_G	1.712	0.98
99_G	131_L	1.698	0.98
224_P	259_I	1.692	0.98
28_I	275_G	1.648	0.98
27_S	142_H	1.623	0.97
118_G	266_L	1.601	0.97
103_W	128_F	1.600	0.97
193_V	224_P	1.567	0.97
148_I	152_R	1.566	0.97
182_L	263_M	1.553	0.96
88_L	101_L	1.550	0.96
170_V	277_L	1.538	0.96
228_T	232_Q	1.524	0.96
89_V	99_G	1.509	0.96
254_V	274_A	1.487	0.95
87_V	90_V	1.486	0.95
19_T	139_R	1.476	0.95
41_H	46_M	1.472	0.95
68_G	78_F	1.452	0.95
128_F	132_P	1.451	0.95
30_A	86_L	1.441	0.95
190_G	200_K	1.428	0.94
245_H	249_I	1.418	0.94
63_S	108_S	1.417	0.94
15_R	160_F	1.416	0.94
235_I	277_L	1.409	0.94
257_H	260_F	1.405	0.94
33_S	127_T	1.389	0.93
95_P	102_H	1.355	0.93
30_A	89_V	1.324	0.92
126_M	276_I	1.315	0.91
284_I	288_I	1.314	0.91
160_F	164_F	1.313	0.91
22_Y	182_L	1.309	0.91
132_P	142_H	1.300	0.91
112_S	115_V	1.291	0.91
151_K	154_L	1.287	0.91
95_P	99_G	1.284	0.90
251_I	255_F	1.265	0.90
261_A	266_L	1.264	0.90
26_R	92_G	1.249	0.89
192_A	198_Q	1.243	0.89
93_W	143_W	1.242	0.89
12_W	164_F	1.231	0.88
90_V	223_I	1.230	0.88
192_A	197_A	1.222	0.88
289_Q	293_I	1.203	0.87
184_Q	196_F	1.203	0.87
93_W	147_P	1.201	0.87
79_R	83_I	1.200	0.87
132_P	262_V	1.199	0.87
170_V	276_I	1.196	0.87
21_V	286_S	1.192	0.87
243_K	247_R	1.189	0.87
255_F	259_I	1.177	0.86
192_A	195_Y	1.162	0.85
89_V	127_T	1.159	0.85
268_S	272_I	1.142	0.84
175_F	233_I	1.142	0.84
18_W	21_V	1.139	0.84
47_K	52_I	1.139	0.84
32_S	268_S	1.138	0.84
181_K	232_Q	1.136	0.84
195_Y	198_Q	1.120	0.83
107_Y	124_A	1.101	0.82
191_T	197_A	1.099	0.82
70_N	80_W	1.086	0.81
232_Q	256_M	1.085	0.81
139_R	145_T	1.085	0.81
23_G	27_S	1.078	0.81
37_L	82_C	1.048	0.79
118_G	264_L	1.045	0.79
106_S	110_Q	1.043	0.78
29_I	33_S	1.041	0.78
227_G	251_I	1.033	0.78
287_T	290_F	1.028	0.77
98_T	101_L	1.023	0.77
29_I	127_T	1.021	0.77
118_G	121_Q	1.020	0.77
266_L	269_F	1.014	0.76
43_S	172_V	1.013	0.76
54_S	254_V	1.007	0.76
250_L	281_L	0.999	0.75
85_I	88_L	0.998	0.75
34_L	42_P	0.987	0.75
40_N	46_M	0.984	0.74
118_G	169_Q	0.982	0.74
192_A	202_I	0.980	0.74
288_I	291_T	0.970	0.73
99_G	132_P	0.969	0.73
275_G	279_L	0.969	0.73
77_L	291_T	0.966	0.73
234_V	238_A	0.966	0.73
202_I	264_L	0.964	0.73
18_W	287_T	0.962	0.73
27_S	90_V	0.957	0.72
23_G	145_T	0.952	0.72
81_V	148_I	0.946	0.71
30_A	103_W	0.936	0.71
86_L	102_H	0.934	0.70
58_C	64_L	0.929	0.70
220_F	259_I	0.920	0.69
167_R	279_L	0.919	0.69
21_V	235_I	0.914	0.69
190_G	195_Y	0.911	0.68
48_P	52_I	0.908	0.68
174_Y	269_F	0.905	0.68
192_A	199_E	0.899	0.67
231_V	239_L	0.898	0.67
16_N	157_I	0.895	0.67
147_P	284_I	0.889	0.67
194_Y	200_K	0.887	0.66
291_T	294_R	0.886	0.66
181_K	257_H	0.886	0.66
93_W	144_S	0.885	0.66
248_L	252_I	0.883	0.66
260_F	270_S	0.882	0.66
122_A	169_Q	0.880	0.66
148_I	153_T	0.878	0.66
19_T	140_K	0.875	0.65
197_A	204_F	0.873	0.65
238_A	245_H	0.870	0.65
20_N	141_W	0.870	0.65
27_S	92_G	0.867	0.65
32_S	275_G	0.867	0.65
68_G	74_M	0.863	0.64
89_V	136_T	0.860	0.64
174_Y	273_M	0.859	0.64
127_T	227_G	0.856	0.64
81_V	152_R	0.854	0.63
95_P	135_L	0.851	0.63
37_L	127_T	0.851	0.63
12_W	100_V	0.851	0.63
190_G	194_Y	0.849	0.63
101_L	105_V	0.849	0.63
190_G	202_I	0.847	0.63
242_P	247_R	0.846	0.63
171_A	275_G	0.844	0.62
196_F	199_E	0.838	0.62
94_R	100_V	0.837	0.62
128_F	227_G	0.835	0.62
130_L	233_I	0.833	0.61
79_R	109_L	0.833	0.61
89_V	98_T	0.823	0.60
220_F	223_I	0.822	0.60
257_H	266_L	0.818	0.60
12_W	167_R	0.818	0.60
65_F	108_S	0.817	0.60
23_G	140_K	0.810	0.59
82_C	105_V	0.809	0.59
193_V	197_A	0.801	0.58
28_I	278_I	0.793	0.58
108_S	112_S	0.793	0.58
148_I	288_I	0.791	0.57
246_W	267_I	0.790	0.57
166_I	213_K	0.786	0.57
131_L	139_R	0.785	0.57
163_Y	166_I	0.782	0.57
31_L	255_F	0.779	0.56
97_I	101_L	0.775	0.56
147_P	151_K	0.774	0.56
205_N	209_Q	0.773	0.56
13_D	240_F	0.770	0.55
284_I	287_T	0.769	0.55
38_L	85_I	0.768	0.55
246_W	269_F	0.767	0.55
152_R	242_P	0.764	0.55
52_I	79_R	0.759	0.54
177_S	228_T	0.755	0.54
36_T	40_N	0.754	0.54
45_I	260_F	0.754	0.54
173_L	276_I	0.752	0.54
16_N	20_N	0.751	0.54
231_V	255_F	0.750	0.53
111_S	119_G	0.743	0.53
91_I	131_L	0.742	0.53
232_Q	235_I	0.742	0.53
155_G	158_T	0.736	0.52
142_H	147_P	0.736	0.52
256_M	259_I	0.734	0.52
117_D	265_G	0.734	0.52
100_V	291_T	0.733	0.52
103_W	124_A	0.733	0.52
224_P	275_G	0.732	0.52
48_P	54_S	0.730	0.51
170_V	292_Y	0.730	0.51
232_Q	270_S	0.729	0.51
33_S	85_I	0.727	0.51
194_Y	197_A	0.726	0.51
247_R	251_I	0.726	0.51
136_T	153_T	0.726	0.51
30_A	92_G	0.724	0.51
177_S	202_I	0.723	0.51
285_D	289_Q	0.723	0.51
17_P	139_R	0.722	0.51
34_L	77_L	0.721	0.51
37_L	102_H	0.720	0.50
166_I	254_V	0.712	0.50
222_V	266_L	0.709	0.49
267_I	270_S	0.709	0.49
247_R	281_L	0.705	0.49
118_G	273_M	0.702	0.49
129_L	165_V	0.702	0.49
285_D	288_I	0.700	0.49
231_V	253_A	0.700	0.49
269_F	273_M	0.697	0.48
270_S	280_Y	0.696	0.48
52_I	179_V	0.696	0.48
230_L	251_I	0.696	0.48
88_L	99_G	0.695	0.48
77_L	160_F	0.693	0.48
106_S	228_T	0.691	0.48
120_E	260_F	0.690	0.48
20_N	287_T	0.682	0.47
158_T	162_S	0.681	0.47
163_Y	167_R	0.677	0.46
30_A	270_S	0.676	0.46
92_G	144_S	0.675	0.46
94_R	248_L	0.670	0.46
94_R	98_T	0.667	0.45
108_S	119_G	0.667	0.45
119_G	232_Q	0.665	0.45
230_L	234_V	0.664	0.45
22_Y	246_W	0.664	0.45
253_A	260_F	0.664	0.45
78_F	85_I	0.664	0.45
177_S	232_Q	0.663	0.45
18_W	22_Y	0.659	0.44
85_I	105_V	0.658	0.44
178_T	193_V	0.656	0.44
145_T	148_I	0.656	0.44
118_G	232_Q	0.656	0.44
114_I	272_I	0.655	0.44
269_F	275_G	0.653	0.44
246_W	270_S	0.651	0.44
97_I	153_T	0.649	0.44
25_A	134_T	0.649	0.44
37_L	141_W	0.648	0.43
47_K	50_S	0.648	0.43
193_V	196_F	0.648	0.43
95_P	143_W	0.644	0.43
130_L	135_L	0.644	0.43
126_M	277_L	0.643	0.43
172_V	293_I	0.642	0.43
145_T	153_T	0.641	0.43
238_A	246_W	0.640	0.43
42_P	170_V	0.638	0.42
84_A	87_V	0.638	0.42
65_F	69_E	0.631	0.42
140_K	289_Q	0.630	0.42
257_H	280_Y	0.629	0.42
172_V	284_I	0.628	0.41
38_L	83_I	0.627	0.41
47_K	51_G	0.626	0.41
194_Y	225_T	0.625	0.41
248_L	251_I	0.625	0.41
35_L	170_V	0.622	0.41
218_S	221_V	0.622	0.41
98_T	132_P	0.621	0.41
151_K	258_E	0.620	0.41
195_Y	199_E	0.620	0.41
21_V	192_A	0.620	0.41
127_T	152_R	0.617	0.40
119_G	270_S	0.617	0.40
117_D	267_I	0.616	0.40
255_F	264_L	0.615	0.40
116_I	119_G	0.613	0.40
84_A	97_I	0.611	0.40
190_G	222_V	0.609	0.40
70_N	77_L	0.609	0.40
117_D	232_Q	0.604	0.39
139_R	142_H	0.601	0.39
165_V	172_V	0.601	0.39
94_R	136_T	0.598	0.39
16_N	155_G	0.595	0.38
227_G	252_I	0.595	0.38
60_M	148_I	0.594	0.38
91_I	288_I	0.589	0.38
121_Q	264_L	0.588	0.38
28_I	81_V	0.587	0.38
194_Y	199_E	0.586	0.38
78_F	108_S	0.585	0.37
148_I	291_T	0.585	0.37
92_G	142_H	0.583	0.37
106_S	123_A	0.581	0.37
51_G	83_I	0.581	0.37
190_G	199_E	0.580	0.37
199_E	202_I	0.578	0.37
237_A	241_A	0.578	0.37
200_K	204_F	0.578	0.37
142_H	145_T	0.577	0.37
238_A	255_F	0.576	0.37
51_G	69_E	0.575	0.37
209_Q	212_T	0.574	0.36
258_E	274_A	0.572	0.36
238_A	242_P	0.571	0.36
230_L	289_Q	0.569	0.36
31_L	35_L	0.568	0.36
181_K	229_L	0.566	0.36
19_T	74_M	0.565	0.36
234_V	284_I	0.563	0.35
82_C	133_I	0.560	0.35
67_L	74_M	0.559	0.35
39_I	273_M	0.559	0.35
134_T	209_Q	0.558	0.35
15_R	20_N	0.557	0.35
23_G	141_W	0.554	0.35
104_Y	142_H	0.553	0.35
249_I	253_A	0.552	0.34
234_V	237_A	0.551	0.34
48_P	51_G	0.551	0.34
91_I	155_G	0.550	0.34
37_L	41_H	0.549	0.34
136_T	142_H	0.548	0.34
23_G	146_R	0.548	0.34
105_V	163_Y	0.548	0.34
139_R	143_W	0.547	0.34
27_S	240_F	0.546	0.34
139_R	148_I	0.544	0.34
111_S	194_Y	0.543	0.34
174_Y	190_G	0.543	0.34
12_W	240_F	0.540	0.33
239_L	245_H	0.540	0.33
35_L	93_W	0.539	0.33
260_F	264_L	0.539	0.33
35_L	90_V	0.538	0.33
47_K	217_T	0.537	0.33
12_W	15_R	0.536	0.33
166_I	176_H	0.534	0.33
233_I	254_V	0.533	0.33
27_S	95_P	0.533	0.33
46_M	258_E	0.532	0.33
239_L	273_M	0.532	0.33
261_A	271_I	0.530	0.33
31_L	64_L	0.528	0.32
80_W	129_L	0.528	0.32
223_I	230_L	0.528	0.32
14_E	161_I	0.528	0.32
21_V	163_Y	0.527	0.32
257_H	269_F	0.527	0.32
159_A	222_V	0.526	0.32
107_Y	111_S	0.522	0.32
36_T	265_G	0.522	0.32
146_R	154_L	0.522	0.32
30_A	169_Q	0.521	0.32
34_L	86_L	0.517	0.31
145_T	179_V	0.516	0.31
116_I	134_T	0.516	0.31
162_S	165_V	0.512	0.31
172_V	256_M	0.512	0.31
101_L	127_T	0.512	0.31
99_G	134_T	0.511	0.31
195_Y	225_T	0.511	0.31
210_A	213_K	0.508	0.31
169_Q	269_F	0.507	0.31
148_I	258_E	0.507	0.31
114_I	199_E	0.506	0.30
250_L	277_L	0.506	0.30
93_W	136_T	0.505	0.30
217_T	254_V	0.505	0.30
125_V	169_Q	0.503	0.30
129_L	169_Q	0.502	0.30
45_I	120_E	0.500	0.30
184_Q	192_A	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2mi2A	1	0.1489	9.1	0.962	Contact Map
2mn6B	2	0.1456	7.3	0.963	Contact Map
2l16A	1	0.1521	5.4	0.966	Contact Map
4ogeA	1	0.165	5.3	0.966	Contact Map
3bu8A	4	0.1068	3.7	0.968	Contact Map
2lzrA	1	0.1489	2.6	0.97	Contact Map
4d6uD	1	0.1942	2.2	0.972	Contact Map
1pp9D	2	0.1942	2	0.972	Contact Map
4jpkA	1	0.1392	1.5	0.974	Contact Map
2qv0A	2	0.1165	1.3	0.975	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0089 seconds.