GREMLIN Database
GERPB - Probable spore germination protein GerPB
UniProt: O06720 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 77 (68)
Sequences: 105 (76)
Seq/√Len: 9.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
5_I30_A3.5240.96
30_A33_I2.6160.84
16_L25_L2.4010.78
14_L25_L2.1160.68
6_N27_I1.9790.63
42_T50_P1.8460.57
4_Y10_Q1.7780.54
25_L73_Q1.7730.54
3_F29_S1.7260.52
18_S38_N1.6780.50
16_L73_Q1.6030.46
32_S35_S1.5610.45
4_Y50_P1.5080.42
3_F6_N1.4280.39
12_N38_N1.4240.39
6_N38_N1.3850.37
15_R24_I1.3840.37
16_L50_P1.3490.36
34_K38_N1.3460.35
17_E20_S1.3110.34
68_S72_L1.2900.33
17_E52_V1.2480.32
14_L17_E1.2140.30
6_N16_L1.2100.30
55_S68_S1.1820.29
63_E68_S1.1730.29
13_Y19_I1.1680.29
8_T27_I1.1280.27
47_E53_S1.0880.26
5_I12_N1.0860.26
29_S33_I1.0850.26
3_F12_N1.0740.25
4_Y54_G1.0670.25
29_S34_K1.0580.25
51_E55_S1.0490.25
39_L49_A1.0370.24
16_L46_V1.0130.23
37_S44_S1.0080.23
3_F73_Q0.9890.23
6_N36_L0.9880.23
46_V67_G0.9740.22
45_Y55_S0.9680.22
39_L70_V0.9650.22
4_Y73_Q0.9210.21
5_I8_T0.8950.20
14_L36_L0.8900.20
12_N19_I0.8890.20
46_V64_P0.8880.20
8_T56_G0.8840.20
30_A36_L0.8770.19
12_N29_S0.8690.19
19_I34_K0.8550.19
8_T51_E0.8390.18
6_N56_G0.8310.18
21_N39_L0.8260.18
47_E51_E0.8240.18
20_S44_S0.8140.18
5_I29_S0.8080.18
20_S66_T0.7950.17
13_Y36_L0.7950.17
35_S54_G0.7900.17
17_E32_S0.7790.17
45_Y66_T0.7650.17
17_E63_E0.7550.16
17_E30_A0.7510.16
32_S54_G0.7500.16
20_S68_S0.7410.16
20_S40_Y0.7350.16
25_L69_L0.7340.16
48_P64_P0.7210.15
56_G65_D0.7150.15
42_T66_T0.6850.15
13_Y48_P0.6830.15
14_L64_P0.6810.15
10_Q19_I0.6770.15
25_L51_E0.6770.15
55_S67_G0.6760.14
53_S56_G0.6680.14
2_N6_N0.6570.14
33_I44_S0.6370.14
52_V68_S0.6330.14
2_N47_E0.6270.13
67_G73_Q0.6200.13
17_E36_L0.6180.13
19_I74_P0.6090.13
14_L19_I0.5990.13
51_E67_G0.5970.13
21_N49_A0.5910.13
39_L69_L0.5900.13
32_S55_S0.5830.13
18_S36_L0.5670.12
46_V69_L0.5630.12
32_S36_L0.5610.12
37_S66_T0.5410.12
20_S46_V0.5350.12
51_E56_G0.5280.12
29_S63_E0.5250.12
12_N30_A0.5160.11
53_S67_G0.5100.11
47_E74_P0.5080.11
65_D73_Q0.5020.11
37_S55_S0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gqbA 1 0.3377 4.6 0.938 Contact Map
1gl4A 1 0.4805 2.9 0.944 Contact Map
4mtlA 4 0.1558 2.5 0.946 Contact Map
3riqA 3 0.6494 2.2 0.947 Contact Map
1mhyB 2 0.3377 2.2 0.948 Contact Map
2yi9A 1 0.2727 2.2 0.948 Contact Map
2yibD 1 0.4286 2.2 0.948 Contact Map
3ub0B 2 0.3377 1.9 0.949 Contact Map
2ahmA 2 0.2078 1.9 0.949 Contact Map
1nnxA 1 0.2597 1.9 0.949 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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