OPUE - BACSU - GREMLIN Contacts

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OPUE - Osmoregulated proline transporter

UniProt:	O06493	Sequences: MSIEIIISLGIYFIAMLLIGWYAFKKTTDINDYMLGGRGLGPFVTALSAGAADMSGWMLMGVPGAMFATGLSTLWLALGLTIGAYSNYLLLAPRLRAYTEAADDAITIPDFFDKRFQHSSSLLKIVSALIIMIFFTLYTSSGMVSGGRLFESAFGADYKLGLFLTTAVVVLYTLFGGFLAVSLTDFVQGAIMFAALVLVPIVAFTHVGGVAPTFHEIDAVNPHLLDIFKGASVISIISYLAWGLGYYGQPHIIVRFMAIKDIKDLKPARRIGMSWMIITVLGSVLTGLIGVAYAHKFGVAVKDPEMIFIIFSKILFHPLITGFLLSAILAAIMSSISSQLLVTASAVTEDLYRSFFRRKASDKELVMIGRLSVLVIAVIAVLLSLNPNSTILDLVGYAWAGFGSAFGPAILLSLYWKRMNEWGALAAMIVGAATVLIWITTGLAKSTGVYEIIPGFILSMIAGIIVSMITKRPAKASYRLFGVMEKLLKRKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	492 (457)
Sequences:	11563 (7270)
Seq/√Len:	340.1

ECOLI - PUTP ACTP PANF YIDK
BACSU - OPUE YCGO YWCA YODF YHJB
HALSA - Q9HR16 Q9HP63
SULSO - Q7LX83 Q97VX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
430_V	462_A	5.817	1.00
361_S	364_E	4.271	1.00
419_M	463_G	3.948	1.00
261_D	264_D	3.875	1.00
357_R	364_E	3.708	1.00
18_L	22_Y	3.534	1.00
430_V	458_L	3.360	1.00
170_V	377_A	3.350	1.00
352_Y	360_A	3.252	1.00
464_I	468_M	3.130	1.00
427_A	463_G	3.123	1.00
97_A	262_I	3.048	1.00
420_N	470_T	3.046	1.00
426_A	466_V	3.042	1.00
201_I	205_T	3.015	1.00
462_A	466_V	2.990	1.00
434_T	458_L	2.988	1.00
203_A	289_I	2.958	1.00
466_V	470_T	2.880	1.00
212_P	215_H	2.815	1.00
363_K	367_M	2.773	1.00
423_G	467_S	2.705	1.00
422_W	470_T	2.625	1.00
412_L	463_G	2.593	1.00
157_D	160_L	2.568	1.00
166_T	381_V	2.548	1.00
367_M	371_L	2.522	1.00
178_F	258_A	2.430	1.00
371_L	375_V	2.417	1.00
40_L	182_S	2.366	1.00
290_G	307_I	2.360	1.00
31_N	38_R	2.305	1.00
113_D	124_K	2.293	1.00
11_I	15_A	2.243	1.00
64_G	305_E	2.201	1.00
426_A	462_A	2.165	1.00
420_N	423_G	2.135	1.00
260_K	264_D	2.124	1.00
416_W	419_M	2.059	1.00
423_G	466_V	2.051	1.00
111_F	413_S	2.043	1.00
163_F	167_A	2.037	1.00
360_A	364_E	2.011	1.00
409_A	424_A	2.002	1.00
378_V	382_L	1.997	1.00
32_D	37_G	1.991	1.00
215_H	219_A	1.989	1.00
197_V	201_I	1.948	1.00
422_W	426_A	1.947	1.00
420_N	467_S	1.932	1.00
116_F	419_M	1.930	1.00
357_R	360_A	1.930	1.00
224_L	228_F	1.928	1.00
56_G	145_S	1.924	1.00
195_A	327_A	1.875	1.00
122_L	425_L	1.870	1.00
423_G	427_A	1.869	1.00
35_L	38_R	1.866	1.00
14_I	18_L	1.864	1.00
349_E	353_R	1.861	1.00
433_A	437_I	1.844	1.00
212_P	216_E	1.834	1.00
263_K	267_P	1.821	1.00
294_A	314_I	1.819	1.00
105_A	114_K	1.777	1.00
263_K	266_K	1.776	1.00
44_V	186_F	1.761	1.00
264_D	267_P	1.759	1.00
416_W	464_I	1.755	1.00
176_G	180_A	1.755	1.00
416_W	468_M	1.752	1.00
461_I	465_I	1.747	1.00
19_I	187_V	1.739	1.00
418_R	471_K	1.734	1.00
169_V	336_I	1.710	1.00
223_H	226_D	1.706	1.00
352_Y	368_I	1.701	1.00
367_M	370_R	1.674	1.00
412_L	460_M	1.671	1.00
322_G	326_S	1.668	1.00
226_D	229_K	1.649	1.00
353_R	365_L	1.632	1.00
352_Y	357_R	1.618	1.00
12_Y	16_M	1.610	1.00
224_L	227_I	1.599	1.00
347_V	351_L	1.590	1.00
42_P	264_D	1.576	1.00
147_G	162_L	1.570	1.00
418_R	468_M	1.570	1.00
47_L	186_F	1.560	1.00
110_D	350_D	1.559	1.00
113_D	121_S	1.541	1.00
215_H	218_D	1.528	1.00
340_L	377_A	1.527	1.00
167_A	171_L	1.524	1.00
148_R	303_D	1.510	1.00
6_I	10_G	1.508	1.00
347_V	372_S	1.504	1.00
430_V	434_T	1.494	1.00
45_T	259_I	1.494	1.00
211_A	215_H	1.493	1.00
310_I	314_I	1.478	1.00
426_A	430_V	1.464	1.00
160_L	164_L	1.461	1.00
185_D	255_R	1.460	1.00
94_R	99_T	1.444	1.00
117_Q	421_E	1.429	1.00
117_Q	122_L	1.420	1.00
91_L	411_L	1.416	1.00
360_A	365_L	1.412	1.00
457_I	461_I	1.411	1.00
364_E	367_M	1.401	1.00
16_M	187_V	1.386	1.00
162_L	381_V	1.381	1.00
352_Y	364_E	1.379	1.00
5_I	319_L	1.371	1.00
207_V	213_T	1.368	1.00
343_T	376_I	1.356	1.00
10_G	14_I	1.353	1.00
15_A	19_I	1.352	1.00
420_N	471_K	1.336	1.00
169_V	333_M	1.323	1.00
166_T	377_A	1.318	1.00
392_L	396_G	1.315	1.00
130_I	432_A	1.312	1.00
115_R	413_S	1.301	1.00
218_D	222_P	1.299	1.00
216_E	219_A	1.289	1.00
110_D	349_E	1.289	1.00
437_I	441_T	1.259	1.00
418_R	472_R	1.253	1.00
185_D	337_S	1.245	1.00
160_L	163_F	1.243	1.00
458_L	462_A	1.235	1.00
129_L	133_I	1.230	1.00
347_V	352_Y	1.221	1.00
184_T	337_S	1.211	1.00
364_E	368_I	1.210	1.00
143_M	166_T	1.209	1.00
124_K	350_D	1.208	1.00
366_V	370_R	1.204	1.00
146_G	165_T	1.203	1.00
111_F	115_R	1.202	1.00
188_Q	337_S	1.198	1.00
29_D	32_D	1.197	1.00
159_K	163_F	1.194	1.00
34_M	369_G	1.193	1.00
113_D	354_S	1.188	1.00
121_S	354_S	1.182	1.00
94_R	97_A	1.181	1.00
66_M	73_T	1.171	1.00
434_T	462_A	1.169	1.00
180_A	185_D	1.168	1.00
228_F	231_A	1.160	1.00
420_N	466_V	1.155	1.00
107_T	345_S	1.155	1.00
52_A	338_S	1.151	1.00
208_G	212_P	1.150	1.00
391_I	395_V	1.150	1.00
419_M	423_G	1.149	1.00
460_M	464_I	1.148	1.00
310_I	313_K	1.142	1.00
126_V	425_L	1.141	1.00
156_A	161_G	1.138	1.00
210_V	214_F	1.137	1.00
36_G	40_L	1.134	1.00
7_I	11_I	1.134	1.00
123_L	425_L	1.134	1.00
348_T	369_G	1.133	1.00
190_A	194_A	1.128	1.00
36_G	178_F	1.128	1.00
48_S	338_S	1.113	1.00
427_A	459_S	1.108	1.00
127_S	428_M	1.107	1.00
362_D	365_L	1.107	1.00
15_A	187_V	1.105	1.00
15_A	18_L	1.105	1.00
163_F	381_V	1.105	1.00
462_A	465_I	1.104	1.00
139_T	380_A	1.104	1.00
418_R	473_P	1.102	1.00
211_A	214_F	1.095	1.00
94_R	98_Y	1.093	1.00
394_L	398_A	1.092	1.00
372_S	375_V	1.089	1.00
216_E	292_A	1.085	1.00
129_L	351_L	1.084	1.00
457_I	460_M	1.079	1.00
151_E	158_Y	1.077	1.00
93_P	97_A	1.074	1.00
368_I	372_S	1.072	1.00
12_Y	333_M	1.071	1.00
48_S	51_A	1.067	1.00
169_V	337_S	1.065	1.00
194_A	198_L	1.062	1.00
181_V	184_T	1.054	1.00
409_A	428_M	1.053	1.00
46_A	271_I	1.049	1.00
312_S	324_L	1.046	1.00
218_D	221_N	1.046	1.00
206_H	293_Y	1.045	1.00
7_I	10_G	1.043	1.00
122_L	126_V	1.043	1.00
427_A	431_G	1.040	1.00
405_A	459_S	1.040	1.00
172_Y	333_M	1.039	1.00
422_W	466_V	1.033	1.00
143_M	162_L	1.028	1.00
452_I	456_F	1.027	1.00
17_L	20_G	1.016	1.00
356_F	360_A	1.015	1.00
442_G	445_K	1.014	1.00
50_G	275_W	1.010	1.00
42_P	46_A	1.009	1.00
74_L	78_L	1.003	1.00
369_G	373_V	1.002	1.00
172_Y	337_S	1.002	1.00
419_M	467_S	0.999	1.00
301_V	304_P	0.999	1.00
421_E	425_L	0.998	1.00
289_I	293_Y	0.997	1.00
454_P	457_I	0.995	1.00
309_I	312_S	0.995	1.00
250_P	254_V	0.994	1.00
185_D	338_S	0.994	1.00
140_S	383_L	0.993	1.00
180_A	184_T	0.993	1.00
396_G	399_W	0.991	1.00
123_L	424_A	0.991	1.00
347_V	376_I	0.990	1.00
360_A	368_I	0.984	1.00
198_L	202_V	0.981	1.00
198_L	320_I	0.980	1.00
221_N	224_L	0.979	1.00
93_P	266_K	0.978	1.00
222_P	226_D	0.973	1.00
27_T	32_D	0.968	1.00
223_H	227_I	0.968	1.00
348_T	368_I	0.962	1.00
121_S	125_I	0.955	1.00
233_V	237_I	0.954	1.00
17_L	21_W	0.953	1.00
204_F	209_G	0.952	1.00
112_F	123_L	0.950	1.00
174_L	374_L	0.949	1.00
250_P	342_V	0.946	1.00
18_L	21_W	0.943	1.00
213_T	289_I	0.939	1.00
79_G	83_G	0.938	1.00
413_S	424_A	0.934	1.00
22_Y	26_K	0.934	1.00
390_T	393_D	0.930	1.00
115_R	416_W	0.927	1.00
112_F	127_S	0.925	1.00
422_W	469_I	0.925	1.00
56_G	332_I	0.924	1.00
126_V	428_M	0.923	1.00
412_L	419_M	0.920	1.00
34_M	345_S	0.918	1.00
116_F	413_S	0.916	1.00
134_F	401_G	0.912	1.00
52_A	185_D	0.911	1.00
303_D	306_M	0.911	1.00
352_Y	356_F	0.905	1.00
395_V	399_W	0.903	1.00
68_A	304_P	0.902	1.00
391_I	396_G	0.897	1.00
412_L	464_I	0.896	1.00
334_S	337_S	0.895	1.00
352_Y	358_R	0.893	1.00
396_G	400_A	0.892	1.00
213_T	217_I	0.891	1.00
200_P	282_G	0.889	1.00
116_F	463_G	0.886	1.00
92_A	96_R	0.885	1.00
431_G	435_V	0.884	1.00
12_Y	330_A	0.884	1.00
290_G	311_F	0.882	1.00
225_L	228_F	0.882	1.00
48_S	182_S	0.881	1.00
341_L	344_A	0.881	1.00
172_Y	334_S	0.879	1.00
408_P	460_M	0.879	1.00
89_L	270_R	0.873	1.00
416_W	467_S	0.873	1.00
172_Y	188_Q	0.871	1.00
182_S	185_D	0.868	1.00
67_F	301_V	0.868	1.00
429_I	433_A	0.867	1.00
158_Y	162_L	0.867	1.00
392_L	395_V	0.864	1.00
460_M	463_G	0.862	1.00
130_I	428_M	0.861	1.00
188_Q	330_A	0.859	1.00
25_K	28_T	0.859	1.00
196_L	283_S	0.858	1.00
270_R	274_S	0.856	1.00
122_L	421_E	0.855	1.00
214_F	218_D	0.855	1.00
156_A	164_L	0.855	1.00
202_V	206_H	0.854	1.00
132_M	347_V	0.852	1.00
86_S	90_L	0.852	1.00
159_K	385_L	0.852	1.00
216_E	220_V	0.851	1.00
465_I	468_M	0.850	1.00
459_S	463_G	0.849	1.00
378_V	381_V	0.848	1.00
42_P	267_P	0.848	1.00
438_W	454_P	0.848	1.00
409_A	459_S	0.846	1.00
375_V	379_I	0.845	1.00
397_Y	439_I	0.844	1.00
55_S	138_Y	0.843	1.00
66_M	288_L	0.841	1.00
344_A	348_T	0.840	1.00
81_T	277_I	0.839	1.00
437_I	440_T	0.838	1.00
233_V	236_I	0.838	1.00
9_L	13_F	0.836	1.00
286_T	311_F	0.835	1.00
47_L	189_G	0.834	1.00
416_W	423_G	0.833	1.00
48_S	255_R	0.832	1.00
259_I	265_L	0.826	1.00
431_G	459_S	0.826	1.00
206_H	315_L	0.825	1.00
458_L	461_I	0.825	1.00
51_A	255_R	0.824	1.00
125_I	355_F	0.823	1.00
214_F	217_I	0.822	1.00
184_T	188_Q	0.822	1.00
222_P	227_I	0.821	1.00
371_L	374_L	0.819	1.00
36_G	258_A	0.818	1.00
172_Y	180_A	0.817	1.00
416_W	420_N	0.816	1.00
48_S	52_A	0.815	1.00
209_G	212_P	0.815	1.00
41_G	264_D	0.815	1.00
67_F	296_K	0.813	1.00
22_Y	25_K	0.812	1.00
13_F	16_M	0.812	1.00
9_L	329_L	0.810	1.00
224_L	229_K	0.809	1.00
423_G	426_A	0.806	1.00
27_T	366_V	0.802	1.00
65_A	69_T	0.801	1.00
425_L	429_I	0.801	1.00
21_W	175_F	0.798	1.00
422_W	471_K	0.797	1.00
77_A	84_A	0.791	1.00
207_V	212_P	0.786	1.00
224_L	230_G	0.786	1.00
16_M	20_G	0.784	1.00
21_W	24_F	0.782	1.00
234_I	238_S	0.781	1.00
90_L	93_P	0.778	1.00
188_Q	334_S	0.778	1.00
162_L	384_S	0.777	1.00
90_L	94_R	0.777	1.00
122_L	125_I	0.775	1.00
5_I	321_T	0.772	1.00
225_L	229_K	0.772	1.00
306_M	310_I	0.771	1.00
188_Q	335_S	0.768	1.00
96_R	99_T	0.767	1.00
249_Q	252_I	0.767	1.00
8_S	319_L	0.766	1.00
151_E	155_G	0.765	1.00
347_V	368_I	0.765	1.00
420_N	472_R	0.764	1.00
312_S	321_T	0.763	1.00
424_A	431_G	0.763	1.00
226_D	230_G	0.763	1.00
199_V	203_A	0.761	1.00
93_P	262_I	0.760	1.00
183_L	186_F	0.759	1.00
109_P	127_S	0.758	1.00
44_V	182_S	0.756	1.00
59_L	324_L	0.753	1.00
198_L	201_I	0.752	1.00
5_I	8_S	0.751	1.00
451_E	455_G	0.751	1.00
442_G	446_S	0.749	1.00
456_F	459_S	0.748	1.00
23_A	27_T	0.746	1.00
83_G	87_N	0.745	1.00
51_A	188_Q	0.743	0.99
199_V	308_F	0.742	0.99
259_I	264_D	0.742	0.99
430_V	466_V	0.741	0.99
76_L	80_L	0.740	0.99
163_F	378_V	0.729	0.99
55_S	59_L	0.728	0.99
232_S	235_S	0.728	0.99
121_S	124_K	0.727	0.99
274_S	278_I	0.727	0.99
465_I	469_I	0.726	0.99
205_T	210_V	0.725	0.99
193_F	197_V	0.725	0.99
432_A	436_L	0.723	0.99
88_Y	92_A	0.723	0.99
353_R	358_R	0.723	0.99
178_F	182_S	0.721	0.99
8_S	322_G	0.721	0.99
223_H	228_F	0.719	0.99
42_P	271_I	0.719	0.99
98_Y	105_A	0.717	0.99
17_L	171_L	0.717	0.99
81_T	273_M	0.716	0.99
412_L	416_W	0.712	0.99
356_F	359_K	0.711	0.99
147_G	158_Y	0.709	0.99
71_L	288_L	0.708	0.99
471_K	474_A	0.707	0.99
24_F	175_F	0.707	0.99
373_V	377_A	0.707	0.99
48_S	185_D	0.706	0.99
150_F	161_G	0.706	0.99
110_D	114_K	0.705	0.99
316_F	320_I	0.702	0.99
126_V	429_I	0.702	0.99
92_A	265_L	0.701	0.99
449_V	453_I	0.701	0.99
22_Y	183_L	0.701	0.99
311_F	315_L	0.699	0.99
58_M	280_V	0.698	0.99
117_Q	474_A	0.697	0.99
40_L	45_T	0.692	0.99
227_I	230_G	0.691	0.99
188_Q	333_M	0.690	0.99
107_T	350_D	0.690	0.99
142_G	336_I	0.688	0.99
117_Q	123_L	0.687	0.99
207_V	292_A	0.686	0.99
335_S	339_Q	0.686	0.99
391_I	394_L	0.686	0.99
461_I	464_I	0.685	0.99
242_W	245_G	0.685	0.99
59_L	196_L	0.682	0.99
418_R	421_E	0.681	0.99
445_K	448_G	0.681	0.99
286_T	308_F	0.678	0.99
142_G	335_S	0.678	0.99
132_M	343_T	0.677	0.99
53_D	399_W	0.676	0.99
33_Y	370_R	0.675	0.99
453_I	457_I	0.675	0.99
11_I	18_L	0.674	0.99
33_Y	373_V	0.674	0.99
109_P	131_I	0.673	0.99
418_R	422_W	0.673	0.99
148_R	305_E	0.673	0.99
202_V	205_T	0.672	0.99
301_V	310_I	0.671	0.99
173_T	337_S	0.671	0.99
464_I	467_S	0.670	0.99
339_Q	342_V	0.667	0.99
161_G	165_T	0.667	0.99
106_I	110_D	0.665	0.99
20_G	24_F	0.665	0.99
12_Y	188_Q	0.663	0.99
146_G	332_I	0.663	0.99
344_A	373_V	0.661	0.99
469_I	472_R	0.661	0.99
344_A	372_S	0.659	0.99
365_L	369_G	0.657	0.99
148_R	151_E	0.657	0.99
434_T	437_I	0.656	0.99
319_L	323_F	0.654	0.99
181_V	255_R	0.654	0.99
76_L	79_G	0.652	0.99
95_L	253_I	0.652	0.99
53_D	80_L	0.651	0.99
8_S	326_S	0.650	0.99
213_T	292_A	0.650	0.99
407_G	411_L	0.650	0.99
435_V	455_G	0.649	0.99
381_V	384_S	0.648	0.99
419_M	427_A	0.647	0.99
291_V	307_I	0.646	0.99
185_D	334_S	0.646	0.99
125_I	129_L	0.645	0.99
466_V	469_I	0.644	0.99
30_I	34_M	0.643	0.99
204_F	210_V	0.641	0.99
340_L	373_V	0.640	0.99
61_G	138_Y	0.640	0.99
181_V	338_S	0.639	0.98
455_G	459_S	0.639	0.98
41_G	44_V	0.638	0.98
94_R	415_Y	0.637	0.98
355_F	358_R	0.636	0.98
313_K	321_T	0.635	0.98
221_N	225_L	0.633	0.98
85_Y	89_L	0.632	0.98
223_H	229_K	0.630	0.98
21_W	25_K	0.629	0.98
43_F	47_L	0.628	0.98
23_A	183_L	0.627	0.98
344_A	369_G	0.627	0.98
395_V	398_A	0.627	0.98
204_F	285_L	0.627	0.98
374_L	378_V	0.620	0.98
213_T	216_E	0.618	0.98
96_R	262_I	0.617	0.98
306_M	309_I	0.617	0.98
220_V	224_L	0.617	0.98
439_I	451_E	0.617	0.98
273_M	277_I	0.617	0.98
235_S	238_S	0.613	0.98
116_F	412_L	0.613	0.98
144_V	148_R	0.613	0.98
170_V	174_L	0.612	0.98
138_Y	339_Q	0.610	0.98
43_F	186_F	0.610	0.98
67_F	307_I	0.610	0.98
222_P	228_F	0.610	0.98
221_N	227_I	0.609	0.98
284_V	288_L	0.609	0.98
131_I	346_A	0.608	0.98
442_G	447_T	0.607	0.98
139_T	336_I	0.606	0.98
32_D	179_L	0.606	0.98
221_N	228_F	0.606	0.98
7_I	14_I	0.605	0.98
433_A	436_L	0.605	0.98
199_V	324_L	0.605	0.98
112_F	409_A	0.604	0.98
434_T	438_W	0.601	0.98
143_M	180_A	0.600	0.98
83_G	243_G	0.600	0.98
222_P	225_L	0.600	0.98
52_A	255_R	0.598	0.98
5_I	322_G	0.598	0.98
125_I	128_A	0.597	0.98
348_T	352_Y	0.596	0.98
50_G	189_G	0.595	0.98
170_V	374_L	0.593	0.98
213_T	288_L	0.592	0.98
51_A	189_G	0.589	0.97
255_R	338_S	0.589	0.97
393_D	396_G	0.589	0.97
124_K	128_A	0.588	0.97
227_I	231_A	0.586	0.97
233_V	238_S	0.585	0.97
291_V	295_H	0.585	0.97
44_V	183_L	0.584	0.97
65_A	73_T	0.584	0.97
45_T	48_S	0.583	0.97
304_P	307_I	0.580	0.97
203_A	315_L	0.580	0.97
72_S	75_W	0.580	0.97
212_P	292_A	0.579	0.97
333_M	337_S	0.579	0.97
116_F	424_A	0.578	0.97
470_T	473_P	0.578	0.97
200_P	285_L	0.577	0.97
353_R	362_D	0.577	0.97
267_P	271_I	0.575	0.97
292_A	295_H	0.574	0.97
138_Y	249_Q	0.574	0.97
71_L	74_L	0.574	0.97
353_R	359_K	0.573	0.97
197_V	200_P	0.573	0.97
46_A	50_G	0.572	0.97
31_N	362_D	0.571	0.97
400_A	435_V	0.570	0.97
434_T	455_G	0.568	0.97
19_I	23_A	0.568	0.97
436_L	440_T	0.568	0.97
188_Q	331_A	0.567	0.97
91_L	99_T	0.567	0.97
172_Y	176_G	0.567	0.97
446_S	454_P	0.566	0.97
293_Y	311_F	0.566	0.97
204_F	213_T	0.566	0.97
279_T	283_S	0.565	0.97
426_A	429_I	0.564	0.97
92_A	95_L	0.564	0.97
77_A	80_L	0.564	0.97
331_A	334_S	0.563	0.97
20_G	23_A	0.562	0.97
456_F	460_M	0.562	0.97
255_R	334_S	0.561	0.97
270_R	273_M	0.561	0.97
179_L	183_L	0.561	0.97
296_K	302_K	0.561	0.97
144_V	158_Y	0.559	0.97
422_W	425_L	0.559	0.97
85_Y	270_R	0.559	0.97
162_L	166_T	0.556	0.96
181_V	185_D	0.555	0.96
316_F	324_L	0.555	0.96
210_V	213_T	0.553	0.96
13_F	20_G	0.552	0.96
26_K	39_G	0.551	0.96
30_I	365_L	0.550	0.96
256_F	269_R	0.550	0.96
387_P	390_T	0.549	0.96
408_P	463_G	0.549	0.96
296_K	301_V	0.549	0.96
55_S	142_G	0.549	0.96
50_G	279_T	0.548	0.96
151_E	157_D	0.548	0.96
424_A	427_A	0.546	0.96
130_I	405_A	0.545	0.96
196_L	282_G	0.544	0.96
142_G	145_S	0.543	0.96
217_I	291_V	0.543	0.96
60_M	145_S	0.543	0.96
41_G	45_T	0.543	0.96
348_T	365_L	0.541	0.96
391_I	399_W	0.540	0.96
379_I	382_L	0.540	0.96
211_A	216_E	0.539	0.96
450_Y	454_P	0.539	0.96
427_A	430_V	0.538	0.96
53_D	276_M	0.537	0.96
220_V	291_V	0.537	0.96
404_S	408_P	0.536	0.96
59_L	64_G	0.536	0.96
12_Y	20_G	0.534	0.95
138_Y	142_G	0.533	0.95
78_L	84_A	0.532	0.95
131_I	406_F	0.531	0.95
339_Q	406_F	0.530	0.95
317_H	320_I	0.528	0.95
166_T	384_S	0.528	0.95
138_Y	250_P	0.528	0.95
242_W	246_Y	0.528	0.95
276_M	280_V	0.527	0.95
431_G	434_T	0.527	0.95
202_V	315_L	0.527	0.95
5_I	20_G	0.524	0.95
57_W	399_W	0.524	0.95
55_S	61_G	0.524	0.95
418_R	464_I	0.523	0.95
123_L	127_S	0.523	0.95
40_L	258_A	0.523	0.95
181_V	341_L	0.522	0.95
294_A	310_I	0.522	0.95
124_K	354_S	0.521	0.95
84_A	87_N	0.520	0.95
260_K	263_K	0.520	0.95
196_L	279_T	0.520	0.95
380_A	384_S	0.519	0.95
26_K	179_L	0.518	0.95
62_V	66_M	0.518	0.95
352_Y	355_F	0.517	0.95
203_A	206_H	0.516	0.95
348_T	372_S	0.516	0.95
54_M	272_G	0.514	0.94
347_V	375_V	0.514	0.94
412_L	467_S	0.514	0.94
468_M	471_K	0.513	0.94
385_L	388_N	0.513	0.94
426_A	470_T	0.513	0.94
148_R	152_S	0.513	0.94
76_L	83_G	0.512	0.94
370_R	373_V	0.512	0.94
244_L	248_G	0.512	0.94
65_A	68_A	0.512	0.94
88_Y	95_L	0.511	0.94
27_T	179_L	0.511	0.94
262_I	266_K	0.509	0.94
52_A	173_T	0.509	0.94
217_I	288_L	0.508	0.94
16_M	23_A	0.507	0.94
359_K	364_E	0.507	0.94
430_V	433_A	0.507	0.94
106_I	349_E	0.507	0.94
115_R	417_K	0.507	0.94
24_F	27_T	0.506	0.94
208_G	211_A	0.505	0.94
318_P	321_T	0.505	0.94
288_L	292_A	0.505	0.94
138_Y	251_H	0.504	0.94
194_A	197_V	0.502	0.94
79_G	84_A	0.502	0.94
463_G	466_V	0.502	0.94
108_I	410_I	0.501	0.94
31_N	106_I	0.501	0.94
114_K	417_K	0.501	0.94
105_A	111_F	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2xq2A	2	0.9411	100	0.214	Contact Map
3dh4A	3	0.8963	100	0.255	Contact Map
3l1lA	2	0.8252	99.4	0.848	Contact Map
3giaA	1	0.8516	99.4	0.851	Contact Map
4wgvA	2	0.7561	99.1	0.865	Contact Map
4djkA	2	0.813	98.8	0.881	Contact Map
2jlnA	1	0.8313	98.7	0.886	Contact Map
4c7rA	3	0.878	97.6	0.914	Contact Map
2wswA	3	0.8171	97.2	0.921	Contact Map
4us3A	1	0.8008	95.9	0.931	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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