GREMLIN Database
TATAY - Sec-independent protein translocase protein TatAy
UniProt: O05522 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 57 (53)
Sequences: 372 (214)
Seq/√Len: 29.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
15_A36_R3.1391.00
27_L34_T2.7941.00
33_D36_R1.9850.97
14_V17_I1.9770.97
2_P29_K1.7980.94
33_D41_A1.7220.93
49_E52_K1.6520.91
26_E33_D1.6230.90
15_A29_K1.6090.90
5_P12_A1.5870.89
2_P5_P1.5160.87
49_E53_K1.4310.84
15_A18_I1.3970.82
29_K36_R1.3530.80
40_N43_K1.2070.72
18_I27_L1.1970.71
22_K46_T1.1800.70
3_I7_S1.1480.68
23_K30_A1.1470.68
41_A44_G1.1420.67
6_G9_A1.1170.66
47_S54_K1.1010.65
7_S35_L1.0800.63
22_K29_K1.0670.62
7_S18_I1.0490.61
34_T41_A1.0350.60
40_N44_G1.0220.59
9_A13_I1.0210.59
51_E54_K1.0200.59
50_E54_K1.0200.59
18_I34_T0.9950.57
22_K26_E0.9910.56
44_G47_S0.9760.55
6_G27_L0.9680.54
39_K45_L0.9520.53
43_K49_E0.9450.53
29_K33_D0.9320.52
10_V26_E0.9160.50
46_T53_K0.9160.50
31_A35_L0.9030.49
3_I6_G0.9030.49
13_I17_I0.8930.49
43_K47_S0.8620.46
22_K45_L0.8600.46
22_K31_A0.8470.45
22_K50_E0.8430.45
46_T49_E0.8240.43
18_I33_D0.8210.43
27_L31_A0.8130.42
11_I18_I0.8070.42
43_K46_T0.7870.40
3_I13_I0.7860.40
10_V15_A0.7800.40
26_E39_K0.7700.39
12_A17_I0.7390.37
8_L12_A0.7290.36
8_L11_I0.7110.35
22_K35_L0.7010.34
33_D42_T0.6990.34
30_A45_L0.6960.34
45_L51_E0.6470.30
5_P8_L0.6470.30
36_R47_S0.6420.30
29_K53_K0.6130.28
6_G44_G0.6060.28
44_G52_K0.6000.27
14_V50_E0.5970.27
18_I49_E0.5950.27
40_N52_K0.5860.27
4_G26_E0.5830.26
13_I52_K0.5770.26
13_I27_L0.5630.25
47_S51_E0.5580.25
9_A31_A0.5350.23
8_L14_V0.5340.23
4_G14_V0.5310.23
10_V29_K0.5300.23
46_T52_K0.5270.23
36_R50_E0.5210.23
18_I50_E0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2l16A 1 0.8772 99.6 0.391 Contact Map
2mn6B 2 0.807 99.5 0.413 Contact Map
2mi2A 1 1 99.5 0.424 Contact Map
2lzrA 1 0.8421 99.4 0.468 Contact Map
1vsy5 1 0.9825 25.9 0.883 Contact Map
2wb0X 1 0.9298 11.4 0.9 Contact Map
4d8pB 1 0 11.3 0.9 Contact Map
3eb7A 2 0.8421 5.1 0.915 Contact Map
1wgxA 1 0.9474 4.7 0.916 Contact Map
2j69A 1 0.9123 4.1 0.919 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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