YDIF - BACSU - GREMLIN Contacts

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YDIF - Uncharacterized ABC transporter ATP-binding protein YdiF

UniProt:	O05519	Sequences: MMILQVNQLSKSFGADTILNNIKLEVRNRDRIAIVGRNGAGKSTLLKIIAGQLSYEKGEIIKPKDITMGYLAQHTGLDSKLTIKEELLTVFDHLKAMEKEMRAMEEKMAAADPGELESIMKTYDRLQQEFKDKGGYQYEADVRSVLHGLGFSHFDDSTQVQSLSGGQKTRLALGKLLLTQPDLLILDEPTNHLDIDTLTWLEHYLQGYSGAILIVSHDRYFLDKVVNQVYEVSRAESKKYHGNYSAYLDQKAAQYEKDLKMYEKQQDEIAKLQDFVDRNLARASTTKRAQSRRKQLERMDVMSKPLGDEKSANFHFDITKQSGNEVLRVQDLTISYENQPPLLTEVSFMLTRGESAALVGPNGIGKSTLLKTLIDTLKPDQGTISYGSNVSVGYYDQEQAELTSSKRVLDELWDEYPGLPEKEIRTCLGNFLFSGDDVLKPVHSLSGGEKARLALAKLMLQKANFLILDEPTNHLDLDSKEVLENALIDYPGTLLFVSHDRYFINRIATRVLELSSSHIEEYLGDYDYYTEKKTEQLELEKMNQQEETDKTPATVKSDSKRSYEEEKEWKKKERQRLRRIEEIETTVQTIEENISRNDELLCDPEVYQDHEKVQAIHADNEKLNQELESLLSEWEELSTEED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	642 (520)
Sequences:	5292 (3622)
Seq/√Len:	158.8

ECOLI - UUP YHES ETTA GSIA YBIT
BACSU - YDIF YFMR YFMM YKPA EXPZ
SULSO - Q980K5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
593_N	619_D	5.054	1.00
579_R	633_E	4.232	1.00
223_D	245_S	4.094	1.00
331_D	345_E	3.928	1.00
273_Q	277_D	3.499	1.00
329_V	332_L	3.424	1.00
405_S	443_H	3.314	1.00
406_K	414_D	3.174	1.00
586_T	626_E	3.144	1.00
505_N	527_D	2.974	1.00
624_N	628_E	2.886	1.00
612_K	615_A	2.775	1.00
334_I	380_D	2.739	1.00
330_Q	383_T	2.724	1.00
228_Q	239_K	2.711	1.00
276_V	293_R	2.684	1.00
609_D	612_K	2.623	1.00
622_K	626_E	2.577	1.00
403_T	406_K	2.541	1.00
594_I	623_L	2.488	1.00
238_K	254_Q	2.485	1.00
334_I	372_T	2.453	1.00
332_L	379_P	2.441	1.00
158_T	162_S	2.404	1.00
341_P	344_T	2.385	1.00
335_S	380_D	2.365	1.00
586_T	630_L	2.352	1.00
587_V	627_L	2.340	1.00
593_N	596_R	2.313	1.00
280_L	293_R	2.309	1.00
246_A	250_Q	2.252	1.00
598_D	620_N	2.245	1.00
618_A	622_K	2.238	1.00
583_I	630_L	2.219	1.00
596_R	600_L	2.212	1.00
590_I	630_L	2.173	1.00
226_V	229_V	2.171	1.00
597_N	616_I	2.170	1.00
582_E	586_T	2.155	1.00
600_L	612_K	2.139	1.00
594_I	620_N	2.129	1.00
262_Y	266_Q	2.112	1.00
615_A	619_D	2.106	1.00
134_G	137_Q	2.106	1.00
619_D	622_K	2.039	1.00
600_L	603_D	2.038	1.00
293_R	297_E	2.016	1.00
370_L	497_V	1.999	1.00
206_Q	224_K	1.989	1.00
141_D	180_Q	1.956	1.00
129_E	133_K	1.936	1.00
249_D	253_A	1.935	1.00
354_E	510_R	1.929	1.00
598_D	624_N	1.921	1.00
240_Y	254_Q	1.914	1.00
333_T	381_Q	1.903	1.00
577_L	581_E	1.883	1.00
246_A	249_D	1.866	1.00
130_F	135_G	1.858	1.00
357_A	504_I	1.855	1.00
350_L	356_A	1.854	1.00
372_T	379_P	1.821	1.00
250_Q	253_A	1.805	1.00
597_N	623_L	1.802	1.00
631_L	635_E	1.780	1.00
590_I	623_L	1.780	1.00
331_D	347_S	1.751	1.00
578_R	581_E	1.749	1.00
589_T	593_N	1.748	1.00
155_D	158_T	1.741	1.00
419_L	423_E	1.737	1.00
290_Q	293_R	1.732	1.00
291_S	294_K	1.731	1.00
593_N	623_L	1.700	1.00
442_V	453_L	1.696	1.00
202_E	224_K	1.693	1.00
588_Q	592_E	1.691	1.00
628_E	632_S	1.681	1.00
592_E	596_R	1.677	1.00
257_K	261_M	1.677	1.00
594_I	624_N	1.676	1.00
268_E	271_K	1.675	1.00
372_T	384_I	1.660	1.00
586_T	589_T	1.656	1.00
614_Q	618_A	1.652	1.00
282_R	285_T	1.643	1.00
290_Q	294_K	1.631	1.00
252_A	256_E	1.629	1.00
159_Q	162_S	1.616	1.00
335_S	341_P	1.614	1.00
620_N	624_N	1.593	1.00
578_R	582_E	1.593	1.00
611_E	615_A	1.591	1.00
253_A	257_K	1.590	1.00
185_I	215_V	1.586	1.00
374_I	467_I	1.585	1.00
356_A	512_L	1.572	1.00
231_E	247_Y	1.562	1.00
580_I	637_L	1.552	1.00
510_R	521_E	1.543	1.00
626_E	630_L	1.530	1.00
329_V	348_F	1.513	1.00
284_S	287_K	1.497	1.00
253_A	256_E	1.486	1.00
626_E	629_S	1.480	1.00
267_D	270_A	1.475	1.00
337_E	341_P	1.475	1.00
343_L	346_V	1.471	1.00
294_K	297_E	1.470	1.00
371_K	376_T	1.470	1.00
585_T	588_Q	1.453	1.00
274_D	277_D	1.443	1.00
372_T	380_D	1.442	1.00
587_V	591_E	1.440	1.00
632_S	635_E	1.437	1.00
357_A	508_A	1.432	1.00
619_D	623_L	1.419	1.00
160_V	171_L	1.410	1.00
574_R	578_R	1.406	1.00
272_L	295_Q	1.406	1.00
588_Q	591_E	1.404	1.00
623_L	626_E	1.398	1.00
595_S	598_D	1.384	1.00
408_V	442_V	1.379	1.00
302_M	305_P	1.379	1.00
600_L	616_I	1.379	1.00
629_S	632_S	1.376	1.00
329_V	373_L	1.376	1.00
122_T	125_R	1.370	1.00
338_N	341_P	1.368	1.00
617_H	621_E	1.363	1.00
273_Q	301_V	1.359	1.00
288_R	296_L	1.359	1.00
598_D	602_C	1.358	1.00
530_T	533_K	1.355	1.00
269_I	301_V	1.349	1.00
230_Y	237_S	1.347	1.00
586_T	590_I	1.341	1.00
408_V	453_L	1.336	1.00
593_N	600_L	1.329	1.00
487_L	494_L	1.323	1.00
529_Y	533_K	1.316	1.00
595_S	599_E	1.311	1.00
629_S	633_E	1.307	1.00
243_N	246_A	1.295	1.00
591_E	627_L	1.294	1.00
404_S	443_H	1.292	1.00
573_E	577_L	1.291	1.00
276_V	296_L	1.291	1.00
344_T	518_H	1.290	1.00
567_K	570_K	1.284	1.00
621_E	625_Q	1.283	1.00
590_I	627_L	1.281	1.00
332_L	372_T	1.279	1.00
496_F	508_A	1.273	1.00
615_A	618_A	1.266	1.00
583_I	637_L	1.262	1.00
594_I	627_L	1.259	1.00
163_L	171_L	1.249	1.00
594_I	598_D	1.249	1.00
625_Q	628_E	1.247	1.00
250_Q	254_Q	1.246	1.00
290_Q	296_L	1.236	1.00
440_K	444_S	1.233	1.00
125_R	129_E	1.230	1.00
128_Q	131_K	1.228	1.00
231_E	251_K	1.228	1.00
525_D	528_Y	1.228	1.00
515_S	520_E	1.225	1.00
632_S	636_E	1.224	1.00
117_E	121_K	1.223	1.00
410_D	413_W	1.217	1.00
618_A	621_E	1.214	1.00
325_E	385_S	1.214	1.00
242_G	250_Q	1.212	1.00
128_Q	132_D	1.209	1.00
348_F	512_L	1.201	1.00
152_S	155_D	1.198	1.00
576_R	637_L	1.198	1.00
568_E	571_K	1.195	1.00
139_E	143_R	1.190	1.00
329_V	384_I	1.187	1.00
407_R	410_D	1.186	1.00
625_Q	629_S	1.185	1.00
290_Q	298_R	1.185	1.00
262_Y	265_Q	1.181	1.00
562_S	565_E	1.177	1.00
230_Y	239_K	1.176	1.00
633_E	636_E	1.173	1.00
294_K	298_R	1.172	1.00
289_A	294_K	1.172	1.00
581_E	585_T	1.170	1.00
411_E	457_K	1.160	1.00
560_K	563_Y	1.158	1.00
292_R	296_L	1.157	1.00
279_N	282_R	1.156	1.00
242_G	246_A	1.155	1.00
291_S	296_L	1.155	1.00
580_I	638_S	1.154	1.00
361_P	364_I	1.152	1.00
288_R	291_S	1.152	1.00
411_E	442_V	1.150	1.00
420_P	423_E	1.150	1.00
291_S	298_R	1.149	1.00
196_D	361_P	1.145	1.00
330_Q	347_S	1.143	1.00
356_A	495_L	1.140	1.00
575_Q	578_R	1.134	1.00
628_E	635_E	1.133	1.00
590_I	594_I	1.131	1.00
292_R	299_M	1.129	1.00
406_K	411_E	1.128	1.00
612_K	616_I	1.126	1.00
328_R	385_S	1.124	1.00
266_Q	269_I	1.122	1.00
185_I	213_L	1.121	1.00
575_Q	579_R	1.119	1.00
121_K	125_R	1.116	1.00
633_E	637_L	1.116	1.00
597_N	620_N	1.113	1.00
287_K	290_Q	1.112	1.00
623_L	627_L	1.111	1.00
289_A	293_R	1.110	1.00
334_I	377_L	1.107	1.00
284_S	288_R	1.101	1.00
168_K	398_E	1.099	1.00
605_E	608_Q	1.097	1.00
259_L	263_E	1.096	0.99
405_S	441_P	1.096	0.99
275_F	288_R	1.095	0.99
579_R	583_I	1.091	0.99
393_G	463_A	1.091	0.99
296_L	299_M	1.089	0.99
183_L	211_A	1.088	0.99
622_K	625_Q	1.087	0.99
419_L	422_K	1.086	0.99
268_E	299_M	1.085	0.99
332_L	384_I	1.085	0.99
280_L	286_T	1.084	0.99
568_E	572_K	1.084	0.99
214_I	226_V	1.080	0.99
563_Y	567_K	1.072	0.99
628_E	631_L	1.071	0.99
463_A	490_Y	1.069	0.99
343_L	372_T	1.068	0.99
406_K	410_D	1.065	0.99
603_D	606_V	1.064	0.99
285_T	288_R	1.059	0.99
561_R	564_E	1.058	0.99
391_S	461_Q	1.058	0.99
596_R	599_E	1.055	0.99
287_K	292_R	1.052	0.99
496_F	507_I	1.052	0.99
437_D	440_K	1.051	0.99
582_E	585_T	1.050	0.99
336_Y	377_L	1.045	0.99
322_S	390_V	1.042	0.99
287_K	291_S	1.041	0.99
601_L	606_V	1.040	0.99
288_R	294_K	1.039	0.99
621_E	624_N	1.039	0.99
220_Y	502_Y	1.035	0.99
180_Q	209_S	1.033	0.99
265_Q	302_M	1.032	0.99
292_R	298_R	1.030	0.99
371_K	377_L	1.026	0.99
528_Y	532_K	1.024	0.99
522_Y	532_K	1.023	0.99
564_E	567_K	1.022	0.99
558_D	561_R	1.022	0.99
269_I	296_L	1.022	0.99
289_A	292_R	1.021	0.99
467_I	495_L	1.021	0.99
288_R	292_R	1.019	0.99
256_E	260_K	1.013	0.99
496_F	503_F	1.012	0.99
386_Y	390_V	1.009	0.99
291_S	299_M	1.004	0.99
563_Y	566_E	1.002	0.99
587_V	631_L	1.001	0.99
289_A	296_L	1.000	0.99
583_I	633_E	0.992	0.99
279_N	285_T	0.992	0.99
289_A	298_R	0.986	0.99
203_H	206_Q	0.985	0.99
565_E	569_W	0.984	0.99
232_V	237_S	0.983	0.99
288_R	293_R	0.982	0.99
367_S	371_K	0.980	0.99
137_Q	141_D	0.978	0.99
286_T	290_Q	0.978	0.99
573_E	576_R	0.977	0.99
537_L	540_E	0.976	0.99
285_T	293_R	0.975	0.99
124_D	128_Q	0.974	0.99
562_S	566_E	0.974	0.99
597_N	619_D	0.974	0.99
255_Y	259_L	0.973	0.99
129_E	132_D	0.972	0.99
293_R	296_L	0.971	0.99
283_A	286_T	0.968	0.99
487_L	507_I	0.968	0.99
604_P	607_Y	0.967	0.99
289_A	300_D	0.964	0.99
422_K	426_T	0.963	0.99
286_T	289_A	0.962	0.99
287_K	293_R	0.955	0.99
205_L	212_I	0.954	0.99
496_F	504_I	0.950	0.99
600_L	619_D	0.949	0.99
574_R	577_L	0.945	0.99
524_G	529_Y	0.945	0.99
616_I	619_D	0.940	0.98
565_E	568_E	0.939	0.98
290_Q	300_D	0.937	0.98
298_R	302_M	0.937	0.98
240_Y	247_Y	0.937	0.98
513_E	529_Y	0.936	0.98
288_R	295_Q	0.936	0.98
465_F	495_L	0.936	0.98
564_E	568_E	0.935	0.98
268_E	272_L	0.935	0.98
468_L	494_L	0.932	0.98
566_E	570_K	0.930	0.98
561_R	565_E	0.927	0.98
299_M	302_M	0.926	0.98
601_L	617_H	0.924	0.98
203_H	207_G	0.921	0.98
583_I	587_V	0.921	0.98
538_E	542_M	0.920	0.98
233_S	238_K	0.919	0.98
585_T	589_T	0.917	0.98
611_E	614_Q	0.916	0.98
277_D	280_L	0.915	0.98
576_R	580_I	0.914	0.98
346_V	512_L	0.911	0.98
281_A	286_T	0.910	0.98
122_T	126_L	0.908	0.98
274_D	278_R	0.906	0.98
409_L	413_W	0.905	0.98
592_E	595_S	0.905	0.98
324_N	351_T	0.905	0.98
601_L	613_V	0.904	0.98
513_E	533_K	0.903	0.98
613_V	617_H	0.899	0.98
291_S	300_D	0.898	0.98
379_P	384_I	0.895	0.98
538_E	541_K	0.895	0.98
333_T	344_T	0.894	0.98
617_H	620_N	0.894	0.98
291_S	295_Q	0.893	0.98
257_K	260_K	0.892	0.98
336_Y	342_L	0.891	0.98
556_K	560_K	0.891	0.98
504_I	508_A	0.890	0.98
477_L	481_E	0.890	0.98
256_E	259_L	0.889	0.98
527_D	531_E	0.888	0.98
571_K	574_R	0.887	0.98
533_K	536_Q	0.886	0.98
614_Q	617_H	0.878	0.98
271_K	274_D	0.876	0.98
559_S	563_Y	0.876	0.98
541_K	544_Q	0.870	0.97
584_E	638_S	0.867	0.97
590_I	593_N	0.867	0.97
320_K	391_S	0.867	0.97
610_H	614_Q	0.866	0.97
297_E	301_V	0.865	0.97
258_D	302_M	0.863	0.97
606_V	613_V	0.861	0.97
599_E	603_D	0.861	0.97
570_K	574_R	0.861	0.97
526_Y	529_Y	0.856	0.97
143_R	153_H	0.856	0.97
576_R	579_R	0.856	0.97
298_R	301_V	0.855	0.97
428_L	431_F	0.851	0.97
528_Y	531_E	0.848	0.97
223_D	243_N	0.848	0.97
559_S	562_S	0.845	0.97
119_I	122_T	0.845	0.97
283_A	290_Q	0.844	0.97
537_L	541_K	0.842	0.97
318_I	491_P	0.841	0.97
284_S	293_R	0.839	0.97
118_S	122_T	0.837	0.97
409_L	424_I	0.835	0.97
160_V	172_A	0.834	0.97
327_L	386_Y	0.834	0.97
593_N	597_N	0.831	0.97
375_D	386_Y	0.831	0.97
330_Q	385_S	0.831	0.97
531_E	534_T	0.823	0.96
328_R	349_M	0.822	0.96
265_Q	299_M	0.822	0.96
543_N	546_E	0.817	0.96
284_S	289_A	0.816	0.96
590_I	626_E	0.815	0.96
627_L	630_L	0.815	0.96
270_A	274_D	0.813	0.96
334_I	368_T	0.813	0.96
181_P	208_Y	0.813	0.96
488_I	506_R	0.811	0.96
519_I	522_Y	0.809	0.96
216_S	222_L	0.802	0.96
278_R	281_A	0.801	0.96
322_S	465_F	0.801	0.96
436_D	439_L	0.799	0.96
560_K	564_E	0.799	0.96
569_W	572_K	0.799	0.96
149_L	174_G	0.795	0.96
285_T	289_A	0.794	0.96
539_L	542_M	0.793	0.96
512_L	521_E	0.791	0.96
529_Y	532_K	0.791	0.96
289_A	299_M	0.791	0.96
335_S	338_N	0.790	0.95
240_Y	250_Q	0.790	0.95
327_L	350_L	0.790	0.95
571_K	578_R	0.788	0.95
542_M	545_Q	0.785	0.95
555_V	558_D	0.783	0.95
300_D	304_K	0.780	0.95
335_S	372_T	0.780	0.95
326_V	493_T	0.776	0.95
536_Q	539_L	0.776	0.95
441_P	444_S	0.772	0.95
372_T	378_K	0.771	0.95
275_F	292_R	0.771	0.95
467_I	497_V	0.770	0.95
127_Q	131_K	0.770	0.95
117_E	120_M	0.769	0.95
515_S	518_H	0.768	0.95
526_Y	530_T	0.768	0.95
413_W	424_I	0.767	0.95
530_T	534_T	0.762	0.95
229_V	243_N	0.762	0.95
373_L	495_L	0.761	0.94
524_G	528_Y	0.761	0.94
572_K	576_R	0.760	0.94
263_E	267_D	0.757	0.94
208_Y	212_I	0.756	0.94
222_L	247_Y	0.756	0.94
426_T	430_N	0.754	0.94
545_Q	548_T	0.751	0.94
335_S	342_L	0.750	0.94
158_T	163_L	0.749	0.94
606_V	616_I	0.748	0.94
323_G	326_V	0.748	0.94
579_R	582_E	0.744	0.94
183_L	213_L	0.743	0.94
126_L	129_E	0.742	0.94
294_K	300_D	0.742	0.94
279_N	286_T	0.741	0.94
393_G	458_L	0.741	0.94
403_T	411_E	0.739	0.94
429_G	434_S	0.738	0.94
260_K	263_E	0.736	0.93
607_Y	613_V	0.736	0.93
152_S	156_D	0.735	0.93
323_G	387_G	0.735	0.93
410_D	414_D	0.734	0.93
425_R	438_V	0.733	0.93
370_L	467_I	0.731	0.93
579_R	586_T	0.727	0.93
275_F	282_R	0.727	0.93
134_G	141_D	0.724	0.93
283_A	288_R	0.721	0.93
610_H	613_V	0.719	0.93
427_C	456_A	0.719	0.93
518_H	521_E	0.719	0.93
564_E	570_K	0.717	0.93
333_T	341_P	0.716	0.93
554_T	558_D	0.716	0.93
591_E	631_L	0.714	0.92
485_N	489_D	0.714	0.92
344_T	516_S	0.714	0.92
575_Q	581_E	0.714	0.92
599_E	602_C	0.711	0.92
275_F	279_N	0.708	0.92
281_A	293_R	0.708	0.92
589_T	592_E	0.707	0.92
260_K	264_K	0.706	0.92
275_F	284_S	0.705	0.92
285_T	290_Q	0.705	0.92
334_I	337_E	0.702	0.92
138_Y	178_L	0.701	0.92
566_E	569_W	0.701	0.92
374_I	392_V	0.700	0.92
423_E	426_T	0.700	0.92
279_N	293_R	0.698	0.92
591_E	595_S	0.696	0.91
543_N	547_E	0.696	0.91
123_Y	127_Q	0.695	0.91
418_G	423_E	0.695	0.91
277_D	282_R	0.695	0.91
619_D	626_E	0.693	0.91
621_E	628_E	0.693	0.91
176_L	184_L	0.692	0.91
350_L	512_L	0.692	0.91
415_E	457_K	0.691	0.91
627_L	631_L	0.691	0.91
286_T	293_R	0.690	0.91
531_E	535_E	0.689	0.91
283_A	287_K	0.689	0.91
557_S	560_K	0.688	0.91
514_L	519_I	0.688	0.91
264_K	268_E	0.687	0.91
419_L	424_I	0.687	0.91
317_D	462_K	0.687	0.91
369_L	373_L	0.684	0.91
289_A	295_Q	0.683	0.91
140_A	144_S	0.681	0.91
557_S	563_Y	0.681	0.91
288_R	300_D	0.681	0.91
364_I	514_L	0.678	0.90
223_D	502_Y	0.673	0.90
293_R	299_M	0.672	0.90
322_S	326_V	0.671	0.90
259_L	262_Y	0.671	0.90
335_S	339_Q	0.670	0.90
254_Q	257_K	0.668	0.90
286_T	292_R	0.667	0.90
584_E	588_Q	0.667	0.90
212_I	225_V	0.664	0.89
354_E	509_T	0.663	0.89
280_L	289_A	0.663	0.89
313_N	316_F	0.663	0.89
532_K	536_Q	0.661	0.89
409_L	438_V	0.661	0.89
296_L	300_D	0.658	0.89
131_K	135_G	0.657	0.89
205_L	225_V	0.657	0.89
288_R	298_R	0.656	0.89
275_F	281_A	0.656	0.89
277_D	281_A	0.655	0.89
408_V	414_D	0.653	0.89
556_K	563_Y	0.653	0.89
634_W	638_S	0.652	0.89
536_Q	540_E	0.651	0.88
558_D	562_S	0.649	0.88
153_H	157_S	0.649	0.88
373_L	384_I	0.648	0.88
554_T	559_S	0.648	0.88
288_R	302_M	0.647	0.88
282_R	286_T	0.647	0.88
138_Y	142_V	0.647	0.88
395_Y	451_A	0.647	0.88
597_N	600_L	0.646	0.88
419_L	460_L	0.646	0.88
386_Y	392_V	0.642	0.88
392_V	465_F	0.641	0.88
532_K	535_E	0.640	0.88
291_S	297_E	0.639	0.88
283_A	291_S	0.639	0.88
279_N	288_R	0.638	0.87
151_F	163_L	0.638	0.87
123_Y	130_F	0.638	0.87
534_T	537_L	0.637	0.87
402_L	411_E	0.636	0.87
268_E	295_Q	0.635	0.87
344_T	381_Q	0.635	0.87
231_E	254_Q	0.635	0.87
206_Q	225_V	0.635	0.87
295_Q	298_R	0.635	0.87
269_I	273_Q	0.634	0.87
153_H	156_D	0.634	0.87
290_Q	297_E	0.634	0.87
151_F	171_L	0.632	0.87
265_Q	269_I	0.632	0.87
359_V	511_V	0.630	0.87
137_Q	140_A	0.629	0.87
275_F	283_A	0.629	0.87
350_L	493_T	0.628	0.87
131_K	136_Y	0.628	0.87
552_P	557_S	0.628	0.87
614_Q	621_E	0.627	0.87
308_D	311_S	0.626	0.86
293_R	298_R	0.625	0.86
303_S	306_L	0.625	0.86
338_N	342_L	0.624	0.86
289_A	302_M	0.624	0.86
333_T	345_E	0.623	0.86
192_H	456_A	0.623	0.86
121_K	124_D	0.623	0.86
412_L	456_A	0.622	0.86
560_K	565_E	0.622	0.86
529_Y	536_Q	0.621	0.86
284_S	290_Q	0.619	0.86
287_K	299_M	0.618	0.86
571_K	581_E	0.617	0.86
291_S	302_M	0.617	0.86
547_E	551_T	0.617	0.86
409_L	439_L	0.616	0.86
429_G	435_G	0.614	0.85
427_C	430_N	0.613	0.85
296_L	302_M	0.613	0.85
604_P	608_Q	0.611	0.85
334_I	343_L	0.611	0.85
554_T	557_S	0.610	0.85
333_T	343_L	0.610	0.85
290_Q	299_M	0.609	0.85
587_V	630_L	0.605	0.85
130_F	136_Y	0.605	0.85
572_K	575_Q	0.604	0.84
545_Q	549_D	0.603	0.84
287_K	298_R	0.603	0.84
593_N	626_E	0.602	0.84
177_L	200_W	0.602	0.84
579_R	637_L	0.601	0.84
269_I	276_V	0.601	0.84
282_R	291_S	0.599	0.84
570_K	573_E	0.598	0.84
331_D	381_Q	0.598	0.84
560_K	566_E	0.597	0.84
609_D	615_A	0.597	0.84
144_S	148_G	0.595	0.84
195_I	199_T	0.594	0.84
287_K	296_L	0.594	0.84
573_E	578_R	0.593	0.83
130_F	134_G	0.593	0.83
350_L	495_L	0.593	0.83
546_E	550_K	0.592	0.83
555_V	560_K	0.590	0.83
160_V	168_K	0.590	0.83
202_E	501_R	0.589	0.83
353_G	493_T	0.589	0.83
542_M	546_E	0.588	0.83
297_E	300_D	0.588	0.83
289_A	297_E	0.588	0.83
541_K	545_Q	0.588	0.83
123_Y	131_K	0.587	0.83
279_N	290_Q	0.587	0.83
287_K	294_K	0.585	0.83
126_L	130_F	0.584	0.82
325_E	328_R	0.584	0.82
557_S	564_E	0.584	0.82
282_R	288_R	0.584	0.82
143_R	147_H	0.583	0.82
404_S	453_L	0.581	0.82
288_R	297_E	0.581	0.82
543_N	595_S	0.581	0.82
272_L	275_F	0.581	0.82
609_D	613_V	0.580	0.82
540_E	543_N	0.579	0.82
297_E	304_K	0.579	0.82
580_I	583_I	0.578	0.82
561_R	567_K	0.578	0.82
594_I	597_N	0.577	0.82
498_S	504_I	0.577	0.82
346_V	519_I	0.576	0.82
552_P	558_D	0.576	0.82
296_L	303_S	0.574	0.81
367_S	401_E	0.573	0.81
244_Y	248_L	0.573	0.81
285_T	295_Q	0.573	0.81
333_T	380_D	0.572	0.81
549_D	553_A	0.572	0.81
220_Y	505_N	0.572	0.81
547_E	555_V	0.570	0.81
518_H	522_Y	0.570	0.81
427_C	460_L	0.570	0.81
238_K	247_Y	0.570	0.81
290_Q	304_K	0.567	0.81
215_V	465_F	0.566	0.80
593_N	622_K	0.566	0.80
228_Q	241_H	0.566	0.80
515_S	533_K	0.565	0.80
556_K	564_E	0.565	0.80
490_Y	494_L	0.564	0.80
555_V	559_S	0.564	0.80
373_L	386_Y	0.563	0.80
544_Q	547_E	0.562	0.80
331_D	334_I	0.561	0.80
610_H	617_H	0.560	0.80
278_R	286_T	0.560	0.80
265_Q	276_V	0.559	0.80
604_P	609_D	0.559	0.80
294_K	302_M	0.558	0.80
378_K	386_Y	0.556	0.79
192_H	473_N	0.556	0.79
567_K	575_Q	0.556	0.79
241_H	246_A	0.556	0.79
269_I	300_D	0.555	0.79
502_Y	506_R	0.554	0.79
264_K	267_D	0.554	0.79
548_T	553_A	0.554	0.79
572_K	579_R	0.553	0.79
344_T	517_S	0.553	0.79
145_V	204_Y	0.553	0.79
275_F	285_T	0.552	0.79
320_K	389_N	0.552	0.79
571_K	575_Q	0.550	0.79
512_L	519_I	0.550	0.79
273_Q	276_V	0.549	0.78
526_Y	533_K	0.549	0.78
387_G	464_N	0.548	0.78
167_Q	395_Y	0.547	0.78
258_D	261_M	0.547	0.78
282_R	293_R	0.546	0.78
606_V	612_K	0.546	0.78
407_R	441_P	0.545	0.78
276_V	280_L	0.545	0.78
323_G	503_F	0.545	0.78
323_G	388_S	0.544	0.78
548_T	556_K	0.544	0.78
155_D	163_L	0.544	0.78
551_T	592_E	0.544	0.78
563_Y	570_K	0.543	0.78
285_T	291_S	0.543	0.78
149_L	200_W	0.543	0.78
293_R	300_D	0.542	0.78
292_R	295_Q	0.542	0.78
533_K	537_L	0.542	0.78
415_E	461_Q	0.540	0.77
498_S	503_F	0.540	0.77
378_K	595_S	0.539	0.77
145_V	178_L	0.538	0.77
591_E	635_E	0.538	0.77
231_E	240_Y	0.537	0.77
243_N	250_Q	0.537	0.77
569_W	573_E	0.537	0.77
355_S	509_T	0.537	0.77
287_K	295_Q	0.537	0.77
355_S	494_L	0.536	0.77
556_K	559_S	0.536	0.77
276_V	297_E	0.535	0.77
630_L	633_E	0.535	0.77
336_Y	341_P	0.534	0.77
327_L	465_F	0.532	0.76
154_F	158_T	0.532	0.76
282_R	290_Q	0.532	0.76
557_S	562_S	0.530	0.76
376_T	396_D	0.530	0.76
515_S	522_Y	0.529	0.76
484_E	506_R	0.529	0.76
627_L	634_W	0.528	0.76
517_S	521_E	0.528	0.76
125_R	128_Q	0.528	0.76
454_A	457_K	0.527	0.76
541_K	552_P	0.527	0.76
260_K	453_L	0.526	0.75
248_L	481_E	0.526	0.75
612_K	619_D	0.526	0.75
173_L	197_T	0.525	0.75
147_H	156_D	0.524	0.75
574_R	581_E	0.523	0.75
625_Q	632_S	0.523	0.75
323_G	389_N	0.523	0.75
288_R	303_S	0.520	0.75
173_L	193_L	0.520	0.75
142_V	145_V	0.517	0.74
275_F	280_L	0.517	0.74
294_K	299_M	0.516	0.74
214_I	225_V	0.515	0.74
351_T	354_E	0.515	0.74
284_S	292_R	0.515	0.74
435_G	438_V	0.514	0.74
265_Q	301_V	0.514	0.74
556_K	562_S	0.511	0.73
162_S	167_Q	0.511	0.73
245_S	249_D	0.510	0.73
618_A	625_Q	0.509	0.73
143_R	156_D	0.509	0.73
281_A	285_T	0.509	0.73
120_M	123_Y	0.508	0.73
284_S	291_S	0.507	0.73
412_L	424_I	0.507	0.73
396_D	400_A	0.506	0.73
570_K	577_L	0.505	0.73
555_V	563_Y	0.504	0.72
354_E	493_T	0.504	0.72
550_K	558_D	0.503	0.72
274_D	280_L	0.503	0.72
535_E	541_K	0.502	0.72
339_Q	516_S	0.502	0.72
338_N	380_D	0.501	0.72
609_D	618_A	0.500	0.72
589_T	629_S	0.500	0.72

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4finA	2	0.8302	100	0.441	Contact Map
2iw3A	2	0.6713	100	0.502	Contact Map
3bk7A	1	0.7819	100	0.552	Contact Map
1yqtA	1	0.7757	100	0.56	Contact Map
3ozxA	1	0.7773	100	0.569	Contact Map
4q9hA	1	0.7679	100	0.57	Contact Map
3j16B	1	0.796	100	0.575	Contact Map
4f4cA	1	0.7212	100	0.577	Contact Map
3ux8A	2	0.6651	100	0.612	Contact Map
2vf7A	2	0.7227	100	0.673	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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