GREMLIN Database
RIMI - Putative ribosomal-protein-alanine acetyltransferase
UniProt: O05517 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 151 (130)
Sequences: 12760 (10130)
Seq/√Len: 888.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
94_V125_M3.1821.00
8_R51_E3.1451.00
24_S77_K2.9751.00
87_E123_F2.6271.00
60_C93_A2.5081.00
87_E122_K2.3991.00
8_R14_D2.2531.00
50_I85_L2.2151.00
62_I93_A2.1621.00
57_A80_Y2.1151.00
127_P130_I2.0931.00
91_R123_F2.0131.00
117_Q121_K1.8591.00
121_K127_P1.8481.00
69_A97_C1.7901.00
94_V105_L1.7751.00
10_M18_V1.7631.00
48_L92_S1.7471.00
58_G76_I1.7331.00
52_K80_Y1.7261.00
92_S95_E1.6671.00
81_R115_P1.6211.00
80_Y83_Q1.6181.00
25_S75_A1.6141.00
19_Y23_A1.6061.00
96_L99_E1.6041.00
49_V56_L1.5911.00
118_G121_K1.5561.00
17_H20_E1.5241.00
16_D32_K1.5091.00
90_F123_F1.5041.00
96_L100_K1.5031.00
47_Y61_G1.4781.00
64_I102_A1.4501.00
24_S78_P1.4481.00
107_L120_Y1.3421.00
46_H96_L1.3361.00
14_D51_E1.3231.00
17_H56_L1.3081.00
10_M49_V1.2981.00
55_H77_K1.2861.00
20_E24_S1.2531.00
111_V130_I1.2441.00
87_E91_R1.2391.00
48_L96_L1.2311.00
92_S96_L1.2241.00
68_D106_S1.2111.00
117_Q127_P1.2101.00
55_H79_E1.1901.00
76_I85_L1.1791.00
46_H100_K1.1721.00
52_K57_A1.1601.00
51_E56_L1.1581.00
52_K83_Q1.1521.00
51_E54_G1.1291.00
105_L125_M1.0761.00
97_C105_L1.0741.00
22_E35_F1.0611.00
88_T91_R1.0571.00
21_I25_S1.0521.00
24_S79_E1.0521.00
114_H117_Q1.0511.00
63_W72_T1.0381.00
62_I97_C1.0351.00
60_C89_L1.0301.00
22_E59_Y1.0261.00
32_K36_Y1.0081.00
109_V113_N1.0081.00
116_A120_Y0.9921.00
68_D104_R0.9911.00
7_V88_T0.9761.00
71_I90_F0.9721.00
82_G115_P0.9641.00
95_E99_E0.9621.00
26_F75_A0.9591.00
60_C71_I0.9561.00
69_A102_A0.9561.00
7_V92_S0.9551.00
97_C102_A0.9441.00
70_Q106_S0.9411.00
11_R14_D0.9411.00
19_Y32_K0.9371.00
84_S87_E0.9351.00
106_S128_G0.9141.00
12_L36_Y0.9131.00
113_N116_A0.8971.00
35_F38_E0.8961.00
15_I19_Y0.8961.00
21_I77_K0.8961.00
114_H118_G0.8931.00
20_E77_K0.8861.00
6_A51_E0.8851.00
77_K80_Y0.8791.00
64_I100_K0.8671.00
17_H55_H0.8631.00
55_H80_Y0.8501.00
52_K55_H0.8291.00
34_S38_E0.8261.00
22_E26_F0.8241.00
31_T34_S0.8211.00
25_S81_R0.8201.00
16_D20_E0.8101.00
7_V48_L0.8081.00
94_V123_F0.8081.00
104_R128_G0.8031.00
90_F119_L0.8011.00
119_L123_F0.7921.00
25_S78_P0.7881.00
88_T92_S0.7871.00
21_I56_L0.7821.00
22_E73_N0.7801.00
109_V116_A0.7691.00
107_L116_A0.7691.00
57_A85_L0.7661.00
28_S31_T0.7601.00
10_M47_Y0.7551.00
38_E61_G0.7491.00
18_V59_Y0.7451.00
91_R95_E0.7371.00
109_V117_Q0.7321.00
9_N48_L0.7291.00
94_V98_K0.7251.00
20_E55_H0.7241.00
10_M15_I0.7231.00
9_N46_H0.7221.00
12_L15_I0.7151.00
46_H62_I0.7081.00
61_G72_T0.7041.00
65_V68_D0.6951.00
70_Q108_E0.6901.00
50_I57_A0.6761.00
86_G119_L0.6551.00
42_N45_A0.6541.00
90_F125_M0.6511.00
8_R49_V0.6511.00
46_H64_I0.6461.00
115_P118_G0.6451.00
50_I58_G0.6371.00
26_F73_N0.6361.00
47_Y51_E0.6331.00
62_I69_A0.6311.00
76_I86_G0.6301.00
85_L88_T0.6291.00
90_F120_Y0.6291.00
58_G85_L0.6181.00
62_I96_L0.6161.00
21_I75_A0.6151.00
17_H21_I0.6101.00
121_K126_Q0.6091.00
116_A119_L0.6071.00
30_W33_D0.6061.00
34_S63_W0.6051.00
64_I69_A0.6051.00
33_D37_H0.6041.00
37_H41_E0.5961.00
118_G122_K0.5931.00
71_I125_M0.5931.00
61_G73_N0.5921.00
58_G89_L0.5921.00
82_G118_G0.5911.00
82_G122_K0.5911.00
10_M14_D0.5891.00
74_I120_Y0.5861.00
16_D19_Y0.5851.00
8_R11_R0.5761.00
76_I89_L0.5711.00
15_I36_Y0.5681.00
20_E23_A0.5661.00
48_L51_E0.5661.00
78_P81_R0.5651.00
80_Y85_L0.5611.00
35_F39_L0.5581.00
36_Y39_L0.5531.00
34_S37_H0.5521.00
38_E45_A0.5521.00
95_E98_K0.5491.00
92_S99_E0.5461.00
60_C74_I0.5441.00
7_V89_L0.5421.00
17_H77_K0.5401.00
114_H121_K0.5381.00
108_E135_Y0.5351.00
6_A54_G0.5291.00
9_N96_L0.5231.00
57_A77_K0.5221.00
91_R94_V0.5171.00
90_F94_V0.5161.00
59_Y75_A0.5151.00
12_L41_E0.5141.00
50_I89_L0.5121.00
74_I90_F0.5111.00
109_V120_Y0.5051.00
18_V56_L0.5021.00
63_W70_Q0.5001.00
38_E42_N0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kvxA 1 0.947 99.9 0.285 Contact Map
4r3lA 1 0.9536 99.9 0.291 Contact Map
4pv6C 3 0.9868 99.9 0.297 Contact Map
3dr6A 2 0.9801 99.9 0.3 Contact Map
2reeA 1 0.9801 99.9 0.301 Contact Map
2ob0A 1 0.9868 99.9 0.305 Contact Map
2cntA 1 0.9669 99.9 0.306 Contact Map
2j8mA 2 0.9801 99.9 0.31 Contact Map
2r7hA 2 0.9669 99.9 0.314 Contact Map
1mk4A 2 0.9603 99.9 0.318 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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