YRPG - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YRPG - Uncharacterized oxidoreductase YrpG

UniProt:	O05408	Sequences: MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGIQFFDTANIYGWGKNAGLTESIIGKWFAQGGQRREKVVLATKVYEPISDPNDGPNDMRGLSLYKIRRHLEGSLKRLQTDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSSNFAGWHLVKAQAEAEKRRFMGLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLAGGLLGGKALKSNAGTRTAKRADLIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPVLTAPIIGPRTVEQLRDTIKAVEISLDKEILRMLNDIFPGPGGETPEAYAW	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	326 (269)
Sequences:	32227 (20421)
Seq/√Len:	1245.1

ECOLI - TAS YDJG YAJO GPR YDHF YEAE YDBC DKGA DKGB
BACSU - YRPG GS69 IOLS YCCK YCSN YQKF YTBE GR
HALSA - Q9HPH9 Q9HQU7 Q9HNN3 Q9HSE6 Q9HS02 Q9HQT1
SULSO - Q97UG6 Q97UJ7 Q97ZZ1 Q97UV9 Q97V56 Q97U17

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
38_E	291_R	3.200	1.00
113_E	153_K	3.050	1.00
29_E	68_K	2.825	1.00
259_L	305_I	2.792	1.00
112_L	148_Q	2.628	1.00
71_A	120_Q	2.516	1.00
302_D	305_I	2.478	1.00
109_R	151_S	2.452	1.00
5_Y	12_R	2.442	1.00
109_R	147_T	2.352	1.00
38_E	42_N	2.350	1.00
258_E	308_M	2.312	1.00
258_E	305_I	2.144	1.00
253_S	257_K	2.095	1.00
33_F	72_Q	2.023	1.00
273_A	306_L	2.017	1.00
82_L	121_T	1.984	1.00
303_K	307_R	1.984	1.00
146_E	150_R	1.981	1.00
114_G	118_R	1.920	1.00
203_A	207_L	1.914	1.00
76_R	79_K	1.907	1.00
123_H	155_D	1.905	1.00
33_F	68_K	1.904	1.00
254_D	308_M	1.897	1.00
147_T	151_S	1.889	1.00
84_T	124_I	1.862	1.00
128_Q	184_T	1.857	1.00
168_V	172_A	1.822	1.00
204_A	211_V	1.816	1.00
105_L	147_T	1.799	1.00
17_C	46_F	1.794	1.00
287_V	291_R	1.794	1.00
147_T	150_R	1.762	1.00
269_A	299_I	1.757	1.00
274_N	310_N	1.747	1.00
261_E	299_I	1.744	1.00
42_N	291_R	1.709	1.00
28_D	31_T	1.682	1.00
84_T	115_S	1.674	1.00
42_N	294_I	1.674	1.00
38_E	287_V	1.656	1.00
105_L	109_R	1.647	1.00
251_K	254_D	1.646	1.00
86_V	108_I	1.636	1.00
262_K	292_D	1.636	1.00
112_L	127_Y	1.631	1.00
210_G	279_A	1.609	1.00
61_L	64_S	1.605	1.00
39_A	44_I	1.604	1.00
295_K	298_E	1.599	1.00
83_A	128_Q	1.595	1.00
33_F	37_D	1.584	1.00
307_R	311_D	1.577	1.00
86_V	127_Y	1.560	1.00
124_I	154_V	1.558	1.00
20_T	47_F	1.551	1.00
109_R	113_E	1.542	1.00
128_Q	212_V	1.530	1.00
168_V	203_A	1.521	1.00
38_E	41_D	1.510	1.00
11_L	156_Y	1.506	1.00
33_F	69_W	1.506	1.00
146_E	180_M	1.503	1.00
144_A	147_T	1.491	1.00
51_N	111_H	1.476	1.00
199_E	202_P	1.465	1.00
31_T	34_R	1.462	1.00
40_L	80_V	1.415	1.00
261_E	265_N	1.402	1.00
110_R	114_G	1.401	1.00
63_E	67_G	1.383	1.00
113_E	117_K	1.369	1.00
205_R	275_P	1.368	1.00
109_R	144_A	1.361	1.00
29_E	33_F	1.357	1.00
202_P	206_D	1.354	1.00
149_V	180_M	1.354	1.00
291_R	295_K	1.353	1.00
11_L	81_V	1.348	1.00
171_Q	203_A	1.345	1.00
148_Q	154_V	1.341	1.00
64_S	118_R	1.330	1.00
308_M	311_D	1.323	1.00
37_D	41_D	1.321	1.00
112_L	124_I	1.309	1.00
163_A	166_H	1.299	1.00
105_L	143_E	1.297	1.00
261_E	266_V	1.296	1.00
36_M	69_W	1.296	1.00
114_G	117_K	1.290	1.00
156_Y	183_V	1.288	1.00
37_D	72_Q	1.287	1.00
269_A	273_A	1.283	1.00
187_H	211_V	1.279	1.00
105_L	144_A	1.274	1.00
154_V	157_I	1.265	1.00
171_Q	207_L	1.262	1.00
262_K	265_N	1.256	1.00
168_V	206_D	1.253	1.00
255_L	266_V	1.251	1.00
284_P	289_Q	1.247	1.00
284_P	290_L	1.240	1.00
67_G	120_Q	1.237	1.00
81_V	126_L	1.236	1.00
47_F	66_I	1.225	1.00
77_R	123_H	1.215	1.00
288_E	291_R	1.213	1.00
251_K	308_M	1.205	1.00
126_L	184_T	1.202	1.00
254_D	258_E	1.201	1.00
34_R	38_E	1.193	1.00
77_R	121_T	1.192	1.00
139_D	173_E	1.179	1.00
9_T	156_Y	1.171	1.00
164_G	203_A	1.171	1.00
191_L	309_L	1.170	1.00
119_L	124_I	1.160	1.00
35_I	290_L	1.145	1.00
30_K	34_R	1.142	1.00
46_F	212_V	1.108	1.00
64_S	68_K	1.106	1.00
37_D	69_W	1.102	1.00
106_Y	110_R	1.101	1.00
132_I	166_H	1.100	1.00
68_K	72_Q	1.096	1.00
271_V	280_P	1.093	1.00
290_L	294_I	1.085	1.00
201_L	205_R	1.082	1.00
146_E	149_V	1.081	1.00
145_F	157_I	1.080	1.00
192_L	249_L	1.074	1.00
113_E	151_S	1.071	1.00
140_E	143_E	1.065	1.00
149_V	183_V	1.062	1.00
107_K	110_R	1.061	1.00
105_L	140_E	1.056	1.00
254_D	257_K	1.054	1.00
189_Y	274_N	1.054	1.00
139_D	169_K	1.051	1.00
168_V	207_L	1.050	1.00
194_R	313_F	1.047	1.00
250_E	254_D	1.045	1.00
252_F	263_E	1.042	1.00
129_M	145_F	1.040	1.00
188_K	193_E	1.038	1.00
46_F	83_A	1.032	1.00
8_R	183_V	1.031	1.00
191_L	267_A	1.028	1.00
45_Q	81_V	1.027	1.00
253_S	263_E	1.021	1.00
272_L	296_A	1.016	1.00
265_N	295_K	1.009	1.00
14_S	45_Q	1.008	1.00
250_E	253_S	1.001	1.00
169_K	173_E	0.999	1.00
148_Q	153_K	0.991	1.00
63_E	115_S	0.986	1.00
159_S	182_L	0.981	1.00
68_K	120_Q	0.975	1.00
5_Y	10_G	0.971	1.00
34_R	287_V	0.969	1.00
14_S	44_I	0.967	1.00
268_L	296_A	0.962	1.00
184_T	212_V	0.961	1.00
164_G	168_V	0.959	1.00
9_T	183_V	0.955	1.00
104_S	107_K	0.953	1.00
36_M	47_F	0.951	1.00
265_N	292_D	0.949	1.00
70_F	80_V	0.943	1.00
148_Q	151_S	0.943	1.00
15_R	272_L	0.942	1.00
125_E	155_D	0.939	1.00
64_S	117_K	0.937	1.00
205_R	277_L	0.924	1.00
143_E	147_T	0.922	1.00
159_S	167_L	0.920	1.00
288_E	292_D	0.919	1.00
292_D	295_K	0.910	1.00
202_P	205_R	0.909	1.00
212_V	279_A	0.906	1.00
109_R	112_L	0.903	1.00
258_E	302_D	0.899	1.00
51_N	107_K	0.898	1.00
198_M	202_P	0.897	1.00
255_L	259_L	0.897	1.00
67_G	71_A	0.884	1.00
83_A	212_V	0.881	1.00
29_E	65_I	0.881	1.00
9_T	149_V	0.878	1.00
274_N	306_L	0.875	1.00
116_L	153_K	0.872	1.00
161_N	214_W	0.872	1.00
304_E	307_R	0.868	1.00
259_L	302_D	0.867	1.00
146_E	157_I	0.861	1.00
307_R	310_N	0.857	1.00
110_R	113_E	0.853	1.00
144_A	148_Q	0.853	1.00
157_I	182_L	0.848	1.00
20_T	66_I	0.845	1.00
15_R	297_V	0.842	1.00
201_L	211_V	0.841	1.00
51_N	90_I	0.840	1.00
304_E	308_M	0.839	1.00
18_L	23_F	0.838	1.00
143_E	146_E	0.838	1.00
20_T	62_T	0.837	1.00
169_K	172_A	0.832	1.00
273_A	300_S	0.825	1.00
243_E	247_L	0.821	1.00
109_R	148_Q	0.820	1.00
185_E	204_A	0.820	1.00
266_V	299_I	0.819	1.00
83_A	126_L	0.816	1.00
194_R	310_N	0.814	1.00
29_E	61_L	0.811	1.00
286_T	289_Q	0.810	1.00
89_P	102_G	0.804	1.00
40_L	76_R	0.800	1.00
167_L	209_L	0.798	1.00
17_C	282_I	0.790	1.00
18_L	39_A	0.785	1.00
261_E	298_E	0.779	1.00
34_R	37_D	0.775	1.00
273_A	303_K	0.770	1.00
216_P	282_I	0.769	1.00
269_A	296_A	0.768	1.00
56_G	63_E	0.762	1.00
142_W	182_L	0.753	1.00
213_A	280_P	0.753	1.00
164_G	200_V	0.752	1.00
35_I	287_V	0.747	1.00
204_A	209_L	0.747	1.00
267_A	271_V	0.745	1.00
131_H	161_N	0.742	1.00
197_E	202_P	0.739	1.00
159_S	185_E	0.738	1.00
189_Y	201_L	0.736	1.00
210_G	278_T	0.736	1.00
213_A	216_P	0.736	1.00
261_E	269_A	0.735	1.00
203_A	206_D	0.733	1.00
261_E	295_K	0.727	1.00
142_W	170_A	0.727	1.00
36_M	40_L	0.725	1.00
227_L	253_S	0.724	1.00
78_E	123_H	0.722	1.00
42_N	295_K	0.722	1.00
112_L	153_K	0.720	1.00
38_E	290_L	0.716	1.00
252_F	309_L	0.716	1.00
66_I	70_F	0.715	1.00
194_R	197_E	0.714	1.00
266_V	301_L	0.710	1.00
84_T	127_Y	0.709	1.00
138_W	173_E	0.706	1.00
259_L	266_V	0.704	1.00
141_I	144_A	0.704	1.00
116_L	121_T	0.703	1.00
171_Q	181_G	0.703	1.00
51_N	118_R	0.702	1.00
149_V	156_Y	0.700	1.00
30_K	33_F	0.699	1.00
270_W	310_N	0.695	1.00
142_W	157_I	0.692	1.00
200_V	204_A	0.690	1.00
257_K	260_G	0.688	1.00
145_F	149_V	0.686	1.00
285_R	289_Q	0.685	1.00
108_I	141_I	0.684	1.00
16_L	272_L	0.679	1.00
115_S	127_Y	0.678	1.00
11_L	155_D	0.678	1.00
159_S	162_F	0.677	1.00
252_F	267_A	0.677	1.00
247_L	250_E	0.676	1.00
108_I	148_Q	0.675	1.00
42_N	290_L	0.675	1.00
255_L	305_I	0.674	1.00
301_L	306_L	0.671	1.00
51_N	114_G	0.671	1.00
111_H	114_G	0.666	1.00
40_L	47_F	0.661	1.00
289_Q	292_D	0.658	1.00
21_M	215_S	0.657	1.00
23_F	35_I	0.657	1.00
44_I	294_I	0.655	1.00
228_K	250_E	0.654	1.00
49_T	66_I	0.652	1.00
249_L	253_S	0.651	1.00
201_L	274_N	0.649	1.00
251_K	312_I	0.648	1.00
76_R	80_V	0.648	1.00
112_L	116_L	0.645	1.00
255_L	308_M	0.644	1.00
246_R	250_E	0.643	1.00
301_L	305_I	0.643	1.00
168_V	171_Q	0.642	1.00
271_V	278_T	0.638	1.00
164_G	199_E	0.637	1.00
31_T	287_V	0.637	1.00
40_L	69_W	0.635	1.00
88_E	91_S	0.634	1.00
45_Q	79_K	0.632	1.00
6_L	210_G	0.631	1.00
63_E	118_R	0.629	1.00
86_V	103_L	0.628	1.00
216_P	271_V	0.627	1.00
22_N	219_G	0.627	1.00
256_C	266_V	0.626	1.00
138_W	141_I	0.626	1.00
35_I	284_P	0.623	1.00
191_L	270_W	0.622	1.00
264_A	292_D	0.621	1.00
72_Q	76_R	0.618	1.00
37_D	76_R	0.613	1.00
124_I	127_Y	0.612	1.00
13_V	46_F	0.611	1.00
256_C	263_E	0.610	1.00
108_I	144_A	0.608	1.00
33_F	65_I	0.607	1.00
104_S	141_I	0.603	1.00
109_R	153_K	0.599	1.00
189_Y	271_V	0.599	1.00
6_L	9_T	0.595	1.00
75_Q	80_V	0.594	1.00
189_Y	194_R	0.594	1.00
32_A	65_I	0.593	1.00
127_Y	154_V	0.593	1.00
128_Q	158_G	0.593	1.00
103_L	129_M	0.593	1.00
52_I	87_Y	0.591	1.00
149_V	154_V	0.591	1.00
116_L	122_D	0.590	1.00
8_R	181_G	0.588	1.00
17_C	281_I	0.588	1.00
13_V	279_A	0.587	1.00
194_R	198_M	0.583	1.00
287_V	290_L	0.580	1.00
116_L	124_I	0.580	1.00
116_L	123_H	0.578	1.00
255_L	312_I	0.576	1.00
224_G	227_L	0.573	1.00
246_R	249_L	0.572	1.00
305_I	308_M	0.571	1.00
62_T	67_G	0.567	1.00
159_S	170_A	0.565	1.00
269_A	297_V	0.563	1.00
266_V	305_I	0.561	1.00
247_L	251_K	0.561	1.00
86_V	111_H	0.556	1.00
23_F	32_A	0.556	1.00
48_D	186_Q	0.555	1.00
189_Y	211_V	0.553	1.00
17_C	279_A	0.549	1.00
61_L	65_I	0.548	1.00
170_A	182_L	0.548	1.00
51_N	87_Y	0.547	1.00
213_A	277_L	0.546	1.00
115_S	118_R	0.545	1.00
269_A	300_S	0.544	1.00
77_R	125_E	0.544	1.00
259_L	299_I	0.539	1.00
255_L	258_E	0.538	1.00
40_L	45_Q	0.536	1.00
256_C	259_L	0.535	1.00
16_L	297_V	0.532	1.00
166_H	169_K	0.528	1.00
165_W	168_V	0.527	1.00
167_L	204_A	0.527	1.00
35_I	285_R	0.526	1.00
227_L	250_E	0.526	1.00
41_D	287_V	0.526	1.00
228_K	243_E	0.525	1.00
127_Y	145_F	0.521	1.00
266_V	309_L	0.521	1.00
171_Q	209_L	0.517	1.00
46_F	81_V	0.517	1.00
56_G	61_L	0.515	1.00
189_Y	278_T	0.514	1.00
272_L	280_P	0.514	1.00
151_S	154_V	0.512	1.00
129_M	141_I	0.512	1.00
50_A	130_H	0.511	1.00
139_D	143_E	0.510	1.00
112_L	144_A	0.510	1.00
252_F	256_C	0.510	1.00
40_L	79_K	0.509	1.00
85_K	130_H	0.509	1.00
68_K	71_A	0.509	1.00
72_Q	75_Q	0.507	1.00
132_I	162_F	0.507	1.00
90_I	107_K	0.507	1.00
113_E	148_Q	0.505	1.00
88_E	131_H	0.504	1.00
49_T	62_T	0.504	1.00
187_H	200_V	0.504	1.00
70_F	76_R	0.502	1.00
223_G	226_A	0.502	1.00
157_I	180_M	0.502	1.00
18_L	35_I	0.500	1.00
91_S	129_M	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1lqaA	2	0.9663	100	0.109	Contact Map
3lutA	3	0.9417	100	0.113	Contact Map
4xk2A	5	0.911	100	0.113	Contact Map
1pyfA	1	0.9172	100	0.118	Contact Map
3eauA	3	0.9448	100	0.118	Contact Map
1pz1A	1	0.9509	100	0.119	Contact Map
2bp1A	2	0.9202	100	0.128	Contact Map
3erpA	6	0.908	100	0.128	Contact Map
3n2tA	1	0.954	100	0.13	Contact Map
3v0sA	1	0.8344	100	0.13	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0098 seconds.