YRBE - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YRBE - Uncharacterized oxidoreductase YrbE

UniProt:	O05389	Sequences: MTKQIVTGIIGAGRIGKLHVQNISRIPHMKIKAISDIQASRIKSWADSHQIEYITSDYRDLLHDPDIDAIFICSPTAVHAQMIKEAAEAKKHIFCEKPVSFSLDETSEALAAVRKHGVTLQVGFNRRFDPHFKKIKTIVENGEIGTPHLLKITSRDPEPPNIDYVRTSGGLFMDMSIHDFDMARYIMGSEVTEVYAKGAALVNPSFAELGDIDTAVITLTFENGAMAVIDNSRQAVYGYDQRVEVFGTKGSAAADNSRPTTVEVSTADFVMKDKPHFFFLERYKDSYEEEILRFAEAIGTNQETPCTGNDGLQAGRIARAAQQSLAFGMPVSIEHTEKIAF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	341 (314)
Sequences:	25590 (19030)
Seq/√Len:	1073.9

ECOLI - YCJS YDGJ YGJR YHHX YJHC YCEM
BACSU - YRBE IOLX NTDC IOLG YFII IOLW YULF YTET
SULSO - Q97UH0 Q97UJ6 Q97UK3 Q97UK0 Q97UJ8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
59_R	85_E	3.186	1.00
80_A	108_E	3.126	1.00
88_E	112_A	2.977	1.00
84_K	112_A	2.768	1.00
39_A	43_K	2.685	1.00
146_T	248_T	2.656	1.00
193_E	220_T	2.652	1.00
80_A	105_E	2.589	1.00
74_S	82_M	2.572	1.00
84_K	88_E	2.503	1.00
6_V	30_K	2.503	1.00
127_R	181_D	2.470	1.00
134_K	137_T	2.462	1.00
8_G	61_L	2.414	1.00
107_S	312_L	2.413	1.00
84_K	108_E	2.385	1.00
136_K	140_E	2.350	1.00
92_H	119_T	2.324	1.00
192_T	222_E	2.312	1.00
33_A	55_T	2.258	1.00
217_I	321_A	2.209	1.00
78_V	82_M	2.209	1.00
80_A	84_K	2.156	1.00
296_E	300_T	2.100	1.00
57_D	60_D	2.087	1.00
87_A	118_V	2.082	1.00
137_T	141_N	2.079	1.00
134_K	138_I	2.024	1.00
83_I	95_C	1.998	1.00
17_K	48_S	1.972	1.00
111_A	115_K	1.923	1.00
81_Q	85_E	1.911	1.00
88_E	116_H	1.872	1.00
114_R	309_N	1.866	1.00
53_Y	64_D	1.840	1.00
112_A	116_H	1.839	1.00
69_A	294_F	1.838	1.00
38_Q	41_R	1.835	1.00
74_S	78_V	1.816	1.00
70_I	86_A	1.805	1.00
7_T	69_A	1.791	1.00
103_L	319_R	1.784	1.00
92_H	118_V	1.783	1.00
8_G	67_I	1.722	1.00
138_I	143_E	1.715	1.00
83_I	109_A	1.701	1.00
26_I	292_L	1.697	1.00
102_S	105_E	1.694	1.00
28_H	299_G	1.682	1.00
221_F	227_A	1.682	1.00
107_S	316_R	1.681	1.00
43_K	47_D	1.678	1.00
136_K	185_Y	1.669	1.00
87_A	113_V	1.661	1.00
144_I	247_G	1.657	1.00
63_H	89_A	1.656	1.00
107_S	111_A	1.652	1.00
112_A	115_K	1.650	1.00
29_M	295_A	1.624	1.00
198_G	325_L	1.612	1.00
23_I	71_F	1.565	1.00
58_Y	85_E	1.561	1.00
62_L	86_A	1.560	1.00
39_A	56_S	1.553	1.00
110_L	312_L	1.540	1.00
67_I	91_K	1.528	1.00
110_L	308_G	1.523	1.00
56_S	60_D	1.498	1.00
120_L	308_G	1.489	1.00
192_T	220_T	1.488	1.00
6_V	32_K	1.481	1.00
60_D	63_H	1.469	1.00
44_S	48_S	1.466	1.00
103_L	107_S	1.465	1.00
88_E	115_K	1.452	1.00
103_L	316_R	1.437	1.00
101_F	105_E	1.436	1.00
123_G	290_E	1.423	1.00
148_H	248_T	1.421	1.00
244_E	253_A	1.415	1.00
313_Q	316_R	1.408	1.00
80_A	109_A	1.406	1.00
59_R	63_H	1.401	1.00
151_K	244_E	1.399	1.00
119_T	301_N	1.375	1.00
85_E	88_E	1.358	1.00
187_M	225_A	1.357	1.00
135_I	252_A	1.356	1.00
197_K	220_T	1.353	1.00
42_I	54_I	1.350	1.00
6_V	68_D	1.347	1.00
87_A	116_H	1.347	1.00
100_S	109_A	1.342	1.00
55_T	64_D	1.336	1.00
100_S	106_T	1.333	1.00
60_D	64_D	1.321	1.00
110_L	309_N	1.313	1.00
106_T	312_L	1.313	1.00
184_R	313_Q	1.305	1.00
189_S	222_E	1.304	1.00
85_E	89_A	1.304	1.00
55_T	61_L	1.287	1.00
90_K	116_H	1.287	1.00
293_R	297_A	1.280	1.00
72_I	83_I	1.276	1.00
151_K	230_D	1.268	1.00
46_A	54_I	1.268	1.00
296_E	302_Q	1.257	1.00
293_R	305_P	1.253	1.00
12_A	34_I	1.236	1.00
110_L	114_R	1.234	1.00
108_E	111_A	1.234	1.00
295_A	299_G	1.228	1.00
35_S	58_Y	1.223	1.00
195_Y	218_T	1.214	1.00
35_S	61_L	1.205	1.00
58_Y	82_M	1.205	1.00
242_R	253_A	1.197	1.00
87_A	112_A	1.189	1.00
44_S	47_D	1.178	1.00
5_I	299_G	1.178	1.00
180_F	317_I	1.169	1.00
25_R	288_E	1.168	1.00
189_S	223_N	1.167	1.00
184_R	221_F	1.162	1.00
144_I	250_G	1.156	1.00
72_I	82_M	1.152	1.00
86_A	93_I	1.149	1.00
319_R	323_Q	1.147	1.00
61_L	67_I	1.142	1.00
94_F	123_G	1.136	1.00
191_V	221_F	1.131	1.00
7_T	29_M	1.128	1.00
58_Y	62_L	1.120	1.00
62_L	85_E	1.118	1.00
94_F	290_E	1.114	1.00
108_E	112_A	1.114	1.00
40_S	43_K	1.111	1.00
320_A	323_Q	1.102	1.00
307_T	310_D	1.099	1.00
99_V	106_T	1.096	1.00
5_I	69_A	1.083	1.00
292_L	296_E	1.083	1.00
5_I	298_I	1.077	1.00
106_T	315_G	1.077	1.00
132_F	185_Y	1.077	1.00
147_P	245_V	1.073	1.00
65_P	91_K	1.066	1.00
21_Q	25_R	1.066	1.00
92_H	298_I	1.061	1.00
156_D	160_P	1.059	1.00
183_A	227_A	1.057	1.00
111_A	114_R	1.048	1.00
75_P	78_V	1.045	1.00
144_I	252_A	1.038	1.00
10_I	82_M	1.037	1.00
150_L	227_A	1.031	1.00
33_A	67_I	1.030	1.00
105_E	108_E	1.024	1.00
184_R	310_D	1.024	1.00
33_A	61_L	1.013	1.00
289_E	292_L	1.009	1.00
95_C	120_L	1.007	1.00
100_S	105_E	1.006	1.00
138_I	141_N	1.004	1.00
137_T	140_E	0.995	1.00
322_Q	326_A	0.992	1.00
288_E	292_L	0.991	1.00
40_S	44_S	0.991	1.00
293_R	296_E	0.987	1.00
191_V	219_L	0.983	1.00
43_K	54_I	0.978	1.00
107_S	110_L	0.975	1.00
103_L	312_L	0.972	1.00
150_L	187_M	0.971	1.00
104_D	108_E	0.968	1.00
144_I	147_P	0.962	1.00
309_N	313_Q	0.960	1.00
296_E	301_N	0.957	1.00
66_D	91_K	0.952	1.00
41_R	44_S	0.950	1.00
82_M	85_E	0.949	1.00
55_T	60_D	0.947	1.00
42_I	46_A	0.945	1.00
78_V	81_Q	0.944	1.00
28_H	292_L	0.944	1.00
42_I	56_S	0.942	1.00
99_V	120_L	0.941	1.00
244_E	251_S	0.940	1.00
189_S	313_Q	0.939	1.00
84_K	109_A	0.938	1.00
293_R	302_Q	0.935	1.00
104_D	107_S	0.930	1.00
127_R	310_D	0.930	1.00
32_K	66_D	0.930	1.00
62_L	89_A	0.928	1.00
21_Q	48_S	0.926	1.00
92_H	301_N	0.925	1.00
135_I	254_A	0.920	1.00
216_V	228_V	0.918	1.00
157_P	160_P	0.917	1.00
320_A	324_S	0.915	1.00
12_A	36_D	0.912	1.00
71_F	291_I	0.909	1.00
147_P	247_G	0.909	1.00
80_A	100_S	0.908	1.00
197_K	226_M	0.907	1.00
121_Q	294_F	0.907	1.00
43_K	46_A	0.907	1.00
316_R	320_A	0.906	1.00
17_K	44_S	0.902	1.00
87_A	93_I	0.894	1.00
77_A	167_T	0.893	1.00
83_I	93_I	0.893	1.00
36_D	42_I	0.892	1.00
19_H	71_F	0.892	1.00
140_E	188_G	0.890	1.00
128_F	293_R	0.888	1.00
39_A	42_I	0.887	1.00
23_I	291_I	0.884	1.00
153_T	242_R	0.883	1.00
113_V	120_L	0.872	1.00
64_D	67_I	0.871	1.00
323_Q	326_A	0.869	1.00
119_T	297_A	0.861	1.00
99_V	308_G	0.861	1.00
36_D	41_R	0.855	1.00
28_H	296_E	0.849	1.00
297_A	302_Q	0.849	1.00
184_R	314_A	0.848	1.00
125_N	286_S	0.835	1.00
83_I	87_A	0.834	1.00
242_R	255_D	0.832	1.00
164_Y	167_T	0.825	1.00
147_P	187_M	0.823	1.00
19_H	291_I	0.822	1.00
196_A	321_A	0.821	1.00
180_F	318_A	0.821	1.00
8_G	33_A	0.820	1.00
45_W	48_S	0.819	1.00
151_K	228_V	0.817	1.00
152_I	179_D	0.814	1.00
152_I	243_V	0.813	1.00
7_T	23_I	0.811	1.00
53_Y	66_D	0.810	1.00
145_G	250_G	0.810	1.00
113_V	116_H	0.803	1.00
219_L	227_A	0.801	1.00
72_I	86_A	0.800	1.00
109_A	120_L	0.797	1.00
32_K	67_I	0.794	1.00
261_T	264_V	0.793	1.00
133_K	137_T	0.791	1.00
124_F	177_I	0.790	1.00
26_I	29_M	0.790	1.00
312_L	316_R	0.786	1.00
32_K	53_Y	0.783	1.00
303_E	307_T	0.782	1.00
191_V	317_I	0.779	1.00
197_K	218_T	0.779	1.00
39_A	54_I	0.779	1.00
8_G	70_I	0.778	1.00
150_L	245_V	0.774	1.00
87_A	120_L	0.770	1.00
139_V	247_G	0.769	1.00
34_I	45_W	0.769	1.00
121_Q	297_A	0.769	1.00
106_T	110_L	0.768	1.00
15_I	73_C	0.767	1.00
15_I	19_H	0.765	1.00
16_G	73_C	0.761	1.00
195_Y	324_S	0.758	1.00
46_A	51_I	0.756	1.00
297_A	300_T	0.754	1.00
133_K	289_E	0.753	1.00
20_V	31_I	0.747	1.00
122_V	311_G	0.746	1.00
9_I	20_V	0.746	1.00
95_C	99_V	0.746	1.00
119_T	298_I	0.745	1.00
6_V	67_I	0.744	1.00
10_I	74_S	0.743	1.00
113_V	308_G	0.739	1.00
297_A	304_T	0.739	1.00
171_L	231_N	0.738	1.00
8_G	35_S	0.736	1.00
23_I	29_M	0.736	1.00
150_L	183_A	0.736	1.00
101_F	168_S	0.731	1.00
30_K	52_E	0.729	1.00
99_V	122_V	0.729	1.00
164_Y	210_G	0.729	1.00
156_D	159_P	0.726	1.00
113_V	118_V	0.723	1.00
153_T	230_D	0.715	1.00
218_T	226_M	0.714	1.00
220_T	226_M	0.713	1.00
146_T	223_N	0.712	1.00
7_T	295_A	0.710	1.00
193_E	197_K	0.710	1.00
294_F	298_I	0.708	1.00
32_K	64_D	0.704	1.00
76_T	174_D	0.701	1.00
172_F	318_A	0.699	1.00
177_I	314_A	0.698	1.00
149_L	246_F	0.697	1.00
176_S	231_N	0.697	1.00
10_I	58_Y	0.696	1.00
191_V	222_E	0.696	1.00
310_D	313_Q	0.696	1.00
132_F	182_M	0.694	1.00
165_V	210_G	0.694	1.00
17_K	21_Q	0.694	1.00
199_A	220_T	0.692	1.00
126_R	129_D	0.689	1.00
213_D	234_Q	0.688	1.00
136_K	186_I	0.688	1.00
149_L	226_M	0.687	1.00
165_V	326_A	0.683	1.00
69_A	92_H	0.683	1.00
262_V	266_T	0.683	1.00
217_I	229_I	0.682	1.00
161_N	164_Y	0.681	1.00
119_T	304_T	0.680	1.00
91_K	118_V	0.678	1.00
90_K	118_V	0.674	1.00
145_G	247_G	0.671	1.00
287_Y	290_E	0.669	1.00
97_K	178_H	0.666	1.00
95_C	109_A	0.661	1.00
38_Q	43_K	0.660	1.00
308_G	311_G	0.656	1.00
64_D	91_K	0.656	1.00
187_M	221_F	0.655	1.00
172_F	215_A	0.654	1.00
119_T	303_E	0.654	1.00
246_F	251_S	0.653	1.00
79_H	95_C	0.650	1.00
17_K	45_W	0.649	1.00
84_K	87_A	0.648	1.00
195_Y	220_T	0.647	1.00
28_H	295_A	0.647	1.00
196_A	217_I	0.645	1.00
259_P	262_V	0.644	1.00
59_R	89_A	0.644	1.00
70_I	91_K	0.644	1.00
15_I	287_Y	0.642	1.00
258_R	261_T	0.641	1.00
221_F	225_A	0.641	1.00
184_R	317_I	0.637	1.00
94_F	121_Q	0.636	1.00
61_L	64_D	0.636	1.00
169_G	173_M	0.635	1.00
133_K	305_P	0.634	1.00
55_T	65_P	0.633	1.00
81_Q	84_K	0.632	1.00
183_A	221_F	0.624	1.00
315_G	319_R	0.623	1.00
10_I	35_S	0.618	1.00
45_W	49_H	0.617	1.00
17_K	41_R	0.617	1.00
136_K	188_G	0.616	1.00
26_I	288_E	0.615	1.00
170_G	212_I	0.614	1.00
80_A	112_A	0.614	1.00
139_V	245_V	0.613	1.00
7_T	71_F	0.612	1.00
81_Q	108_E	0.612	1.00
69_A	298_I	0.610	1.00
284_K	288_E	0.609	1.00
77_A	101_F	0.608	1.00
127_R	185_Y	0.606	1.00
6_V	66_D	0.603	1.00
83_I	120_L	0.602	1.00
35_S	55_T	0.601	1.00
212_I	322_Q	0.599	1.00
124_F	314_A	0.599	1.00
184_R	189_S	0.599	1.00
176_S	179_D	0.599	1.00
87_A	109_A	0.597	1.00
214_T	232_S	0.596	1.00
17_K	49_H	0.596	1.00
20_V	45_W	0.595	1.00
16_G	21_Q	0.591	1.00
133_K	185_Y	0.590	1.00
26_I	295_A	0.589	1.00
180_F	321_A	0.588	1.00
130_P	289_E	0.588	1.00
289_E	293_R	0.588	1.00
172_F	217_I	0.587	1.00
12_A	45_W	0.585	1.00
41_R	45_W	0.585	1.00
162_I	174_D	0.584	1.00
296_E	299_G	0.583	1.00
14_R	18_L	0.582	1.00
253_A	263_E	0.582	1.00
95_C	122_V	0.580	1.00
186_I	245_V	0.578	1.00
232_S	235_A	0.576	1.00
293_R	304_T	0.574	1.00
121_Q	293_R	0.573	1.00
201_L	213_D	0.570	1.00
142_G	146_T	0.568	1.00
12_A	42_I	0.567	1.00
110_L	113_V	0.567	1.00
135_I	186_I	0.564	1.00
16_G	45_W	0.564	1.00
183_A	229_I	0.563	1.00
264_V	267_A	0.563	1.00
173_M	319_R	0.561	1.00
139_V	186_I	0.559	1.00
146_T	249_K	0.557	1.00
37_I	74_S	0.557	1.00
198_G	215_A	0.555	1.00
152_I	183_A	0.554	1.00
121_Q	290_E	0.553	1.00
125_N	287_Y	0.552	1.00
21_Q	24_S	0.552	1.00
219_L	229_I	0.551	1.00
29_M	69_A	0.551	1.00
218_T	228_V	0.550	1.00
124_F	181_D	0.550	1.00
199_A	214_T	0.549	1.00
285_D	288_E	0.549	1.00
147_P	225_A	0.548	1.00
33_A	53_Y	0.548	1.00
278_F	281_E	0.547	1.00
182_M	243_V	0.541	1.00
153_T	240_D	0.540	1.00
181_D	185_Y	0.539	1.00
181_D	314_A	0.538	1.00
318_A	322_Q	0.537	1.00
72_I	79_H	0.533	1.00
113_V	117_G	0.533	1.00
63_H	85_E	0.531	1.00
216_V	230_D	0.531	1.00
196_A	215_A	0.529	1.00
202_V	213_D	0.527	1.00
35_S	56_S	0.527	1.00
15_I	96_E	0.526	1.00
128_F	306_C	0.526	1.00
9_I	71_F	0.525	1.00
59_R	81_Q	0.525	1.00
9_I	31_I	0.525	1.00
162_I	165_V	0.523	1.00
19_H	23_I	0.522	1.00
22_N	26_I	0.521	1.00
126_R	181_D	0.520	1.00
68_D	299_G	0.518	1.00
214_T	230_D	0.516	1.00
258_R	262_V	0.515	1.00
155_R	230_D	0.514	1.00
314_A	318_A	0.513	1.00
67_I	70_I	0.513	1.00
71_F	94_F	0.513	1.00
136_K	139_V	0.513	1.00
216_V	226_M	0.512	1.00
261_T	266_T	0.512	1.00
133_K	136_K	0.511	1.00
58_Y	86_A	0.511	1.00
129_D	286_S	0.510	1.00
184_R	191_V	0.508	1.00
260_T	263_E	0.508	1.00
149_L	230_D	0.506	1.00
187_M	223_N	0.505	1.00
5_I	29_M	0.505	1.00
149_L	228_V	0.504	1.00
102_S	319_R	0.501	1.00
69_A	295_A	0.501	1.00
259_P	263_E	0.500	1.00
74_S	79_H	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3euwA	4	0.9736	100	0.194	Contact Map
1h6dA	8	0.9883	100	0.196	Contact Map
3ezyA	4	0.9795	100	0.2	Contact Map
4mkxA	4	0.9707	100	0.204	Contact Map
3dtyA	4	0.956	100	0.204	Contact Map
1zh8A	2	0.9208	100	0.206	Contact Map
3v5nA	4	0.915	100	0.207	Contact Map
2nvwA	3	0.9501	100	0.209	Contact Map
3ceaA	4	0.9736	100	0.213	Contact Map
3db2A	2	0.9648	100	0.215	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0106 seconds.