GREMLIN Database
ASNO - Asparagine synthetase [glutamine-hydrolyzing] 3
UniProt: O05272 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 614 (577)
Sequences: 4503 (3586)
Seq/√Len: 149.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_D60_R3.9821.00
176_R200_K3.7521.00
25_T47_G3.7521.00
290_H327_T3.6601.00
116_D119_D3.4481.00
64_A73_T3.3851.00
95_H112_E3.3831.00
136_L214_S3.3731.00
93_R112_E3.3631.00
272_A516_L3.3541.00
21_M45_L3.2181.00
109_S113_W3.2051.00
89_E120_H3.0811.00
262_T274_T3.0621.00
245_L493_Y3.0481.00
367_E370_K3.0181.00
136_L212_T2.9261.00
139_A149_F2.9221.00
247_Q279_G2.8941.00
144_L491_V2.8121.00
318_E330_K2.7601.00
234_S237_D2.7061.00
59_G101_S2.6901.00
261_C372_F2.6891.00
319_K523_D2.6701.00
109_S117_C2.6501.00
514_K517_E2.5831.00
146_V483_V2.5731.00
65_C69_G2.5431.00
292_Y371_D2.5331.00
347_L606_A2.5241.00
246_F276_I2.4921.00
36_S49_K2.4511.00
243_R518_G2.4241.00
205_I211_L2.4121.00
128_A139_A2.4081.00
113_W120_H2.3971.00
165_K350_D2.3921.00
235_F514_K2.3361.00
210_A221_W2.3091.00
74_I103_T2.3091.00
601_H605_E2.2811.00
143_R488_H2.2541.00
318_E322_E2.2241.00
117_C121_L2.2101.00
209_H222_R2.1611.00
178_D200_K2.1561.00
206_R220_I2.1541.00
248_D489_R2.1381.00
474_S481_V2.1291.00
290_H329_H2.0981.00
522_D526_Y2.0851.00
159_L170_H2.0741.00
252_R489_R2.0721.00
65_C111_I2.0491.00
158_F213_F2.0111.00
235_F501_M2.0111.00
135_N215_K2.0021.00
291_T326_T1.9941.00
118_V210_A1.9911.00
6_G160_F1.9891.00
206_R209_H1.9851.00
88_K91_R1.9661.00
504_H510_G1.9541.00
293_S317_I1.9091.00
178_D195_G1.8961.00
122_N489_R1.8611.00
233_D238_T1.8541.00
518_G522_D1.8531.00
125_F140_A1.8521.00
95_H108_H1.8481.00
369_K373_V1.8481.00
110_Y129_V1.8451.00
241_N244_S1.8321.00
139_A211_L1.8281.00
84_E255_V1.8231.00
122_N488_H1.8161.00
54_V83_T1.8091.00
118_V140_A1.7971.00
146_V253_Q1.7911.00
517_E526_Y1.7891.00
65_C71_T1.7871.00
274_T326_T1.7851.00
317_I321_T1.7761.00
214_S217_G1.7721.00
209_H220_I1.7711.00
241_N245_L1.7701.00
115_E221_W1.7651.00
381_A485_F1.7531.00
488_H492_E1.7451.00
106_L121_L1.7361.00
73_T132_E1.7191.00
271_S320_M1.7191.00
65_C108_H1.7171.00
243_R515_A1.6961.00
366_R370_K1.6921.00
130_W137_L1.6871.00
365_C474_S1.6811.00
115_E212_T1.6771.00
30_K163_E1.6761.00
344_E366_R1.6711.00
235_F510_G1.6611.00
254_L277_A1.6601.00
248_D252_R1.6601.00
76_Y80_L1.6591.00
242_V385_F1.6581.00
233_D241_N1.6481.00
151_Y203_K1.6361.00
316_W527_R1.6301.00
71_T133_K1.6121.00
243_R519_I1.6101.00
138_F212_T1.6091.00
72_Y107_L1.6071.00
251_T280_H1.6041.00
238_T497_I1.6021.00
122_N248_D1.5961.00
122_N487_D1.5951.00
385_F494_V1.5911.00
127_F140_A1.5851.00
204_E351_L1.5691.00
178_D203_K1.5661.00
69_G111_I1.5631.00
161_G166_A1.5621.00
489_R492_E1.5611.00
242_V493_Y1.5611.00
122_N252_R1.5551.00
72_Y111_I1.5531.00
510_G514_K1.5481.00
110_Y138_F1.5471.00
41_E132_E1.5431.00
235_F239_V1.5391.00
130_W135_N1.5151.00
22_D36_S1.5151.00
560_H601_H1.5141.00
5_T25_T1.5051.00
154_E157_S1.4991.00
291_T328_H1.4981.00
118_V138_F1.4941.00
22_D26_D1.4831.00
448_D499_W1.4801.00
110_Y117_C1.4641.00
211_L218_L1.4511.00
117_C138_F1.4441.00
131_D134_R1.4301.00
247_Q276_I1.4231.00
109_S121_L1.4181.00
138_F210_A1.4121.00
25_T38_V1.3991.00
153_K203_K1.3831.00
241_N493_Y1.3811.00
517_E522_D1.3761.00
53_V374_V1.3661.00
117_C127_F1.3551.00
83_T255_V1.3551.00
74_I129_V1.3521.00
348_V476_G1.3481.00
379_E469_R1.3471.00
115_E138_F1.3451.00
249_A253_Q1.3351.00
235_F504_H1.3341.00
336_K340_D1.3321.00
20_T171_P1.3301.00
239_V514_K1.3291.00
22_D38_V1.3181.00
247_Q280_H1.3171.00
297_E334_S1.3121.00
89_E113_W1.3121.00
5_T24_M1.3111.00
25_T49_K1.3101.00
334_S337_D1.3101.00
272_A515_A1.3071.00
233_D237_D1.3031.00
274_T324_F1.3021.00
8_V44_V1.3021.00
80_L106_L1.3021.00
574_T582_P1.2951.00
569_D573_E1.2921.00
557_S561_T1.2861.00
28_L166_A1.2831.00
21_M47_G1.2831.00
5_T47_G1.2791.00
329_H371_D1.2671.00
29_S49_K1.2661.00
83_T105_V1.2641.00
243_R247_Q1.2631.00
76_Y103_T1.2531.00
545_S549_K1.2521.00
245_L490_L1.2521.00
6_G128_A1.2411.00
108_H111_I1.2391.00
224_W492_E1.2351.00
124_I146_V1.2341.00
159_L167_I1.2311.00
140_A210_A1.2291.00
252_R255_V1.2281.00
106_L117_C1.2271.00
167_I173_I1.2261.00
29_S36_S1.2261.00
74_I107_L1.2251.00
319_K322_E1.2181.00
239_V515_A1.2141.00
106_L127_F1.2131.00
549_K573_E1.2071.00
46_F160_F1.2041.00
497_I511_I1.2011.00
575_E581_V1.1931.00
28_L49_K1.1911.00
262_T291_T1.1911.00
39_W73_T1.1831.00
238_T501_M1.1831.00
222_R225_N1.1811.00
83_T100_T1.1801.00
404_R408_E1.1731.00
448_D451_R1.1731.00
242_V490_L1.1711.00
274_T291_T1.1701.00
276_I519_I1.1691.00
391_F457_L1.1621.00
164_I202_I1.1621.00
87_R97_F1.1611.00
26_D49_K1.1611.00
8_V137_L1.1531.00
430_K433_E1.1521.00
565_R569_D1.1501.00
184_E195_G1.1481.00
314_G330_K1.1481.00
54_V255_V1.1461.00
271_S520_L1.1441.00
245_L489_R1.1441.00
71_T134_R1.1321.00
6_G139_A1.1290.99
54_V256_S1.1280.99
557_S601_H1.1260.99
273_I376_L1.1260.99
246_F485_F1.1260.99
570_Q574_T1.1230.99
74_I127_F1.1230.99
240_A244_S1.1190.99
337_D340_D1.1160.99
253_Q483_V1.1150.99
18_K22_D1.1130.99
208_A224_W1.1100.99
57_E99_R1.1100.99
377_S481_V1.1090.99
168_L175_A1.1080.99
240_A518_G1.1060.99
549_K572_L1.1060.99
297_E332_V1.1050.99
493_Y497_I1.1010.99
122_N253_Q1.1000.99
176_R201_G1.0970.99
124_I253_Q1.0940.99
84_E100_T1.0920.99
368_I375_S1.0910.99
248_D251_T1.0900.99
27_T169_A1.0860.99
470_K481_V1.0850.99
66_T111_I1.0800.99
35_D48_H1.0730.99
128_A160_F1.0700.99
129_V138_F1.0700.99
256_S260_V1.0700.99
364_F368_I1.0680.99
278_A324_F1.0630.99
63_M107_L1.0610.99
66_T108_H1.0590.99
126_A149_F1.0570.99
199_F607_Y1.0560.99
65_C70_D1.0550.99
71_T111_I1.0540.99
93_R113_W1.0520.99
205_I220_I1.0490.99
547_W550_T1.0480.99
167_I202_I1.0460.99
115_E136_L1.0360.99
43_H135_N1.0340.99
567_Q570_Q1.0320.99
550_T553_S1.0300.99
37_N60_R1.0300.99
186_F600_I1.0290.99
74_I106_L1.0240.99
46_F75_I1.0200.99
350_D472_R1.0160.99
171_P175_A1.0150.99
59_G99_R1.0140.99
71_T132_E1.0130.99
349_K473_M1.0100.99
95_H111_I1.0090.99
26_D36_S1.0060.99
288_P327_T1.0060.99
271_S316_W1.0060.99
337_D366_R1.0030.99
563_L568_L1.0010.99
63_M103_T1.0010.99
97_F105_V0.9990.99
118_V127_F0.9950.99
24_M170_H0.9950.99
529_K532_Y0.9850.99
72_Y133_K0.9840.99
72_Y110_Y0.9830.99
386_G503_M0.9770.99
295_D314_G0.9760.99
277_A289_L0.9700.98
246_F272_A0.9670.98
94_G97_F0.9650.98
213_F218_L0.9620.98
557_S560_H0.9570.98
91_R94_G0.9540.98
341_H366_R0.9540.98
242_V494_V0.9530.98
128_A137_L0.9500.98
556_D605_E0.9490.98
52_A56_I0.9490.98
298_E310_P0.9480.98
152_T173_I0.9480.98
273_I485_F0.9440.98
242_V246_F0.9430.98
228_S495_W0.9410.98
4_I48_H0.9410.98
35_D52_A0.9390.98
193_T464_T0.9370.98
451_R502_K0.9350.98
451_R454_L0.9350.98
246_F516_L0.9350.98
551_I598_A0.9340.98
19_Q22_D0.9320.98
83_T87_R0.9260.98
549_K569_D0.9250.98
555_K559_L0.9240.98
245_L248_D0.9220.98
560_H565_R0.9220.98
263_F368_I0.9200.98
25_T36_S0.9200.98
127_F138_F0.9190.98
507_R513_R0.9190.98
65_C72_Y0.9180.98
341_H363_W0.9180.98
249_A487_D0.9170.98
494_V497_I0.9160.98
152_T167_I0.9160.98
4_I75_I0.9150.98
21_M25_T0.9140.98
21_M38_V0.9140.98
25_T28_L0.9130.98
550_T554_Q0.9120.98
82_N85_D0.9100.98
2_C77_N0.8960.97
380_C486_A0.8960.97
485_F512_L0.8950.97
239_V243_R0.8950.97
184_E192_R0.8840.97
139_A160_F0.8840.97
295_D332_V0.8840.97
158_F205_I0.8820.97
134_R214_S0.8810.97
258_V374_V0.8800.97
88_K92_A0.8770.97
362_L477_A0.8760.97
320_M524_I0.8740.97
343_E602_T0.8720.97
124_I147_K0.8710.97
5_T161_G0.8700.97
28_L161_G0.8700.97
262_T277_A0.8690.97
545_S576_G0.8680.97
40_G45_L0.8640.97
355_A469_R0.8620.97
279_G519_I0.8620.97
498_P501_M0.8610.97
275_A519_I0.8610.97
81_Y124_I0.8590.97
250_V273_I0.8580.97
316_W320_M0.8570.97
3_G31_R0.8570.97
601_H604_F0.8570.97
314_G332_V0.8570.97
225_N459_M0.8560.97
239_V242_V0.8520.96
150_F472_R0.8510.96
554_Q557_S0.8510.96
110_Y115_E0.8490.96
515_A518_G0.8460.96
554_Q558_V0.8440.96
471_D475_M0.8440.96
89_E93_R0.8440.96
241_N496_N0.8430.96
85_D252_R0.8400.96
455_F459_M0.8400.96
568_L597_L0.8390.96
379_E470_K0.8360.96
275_A324_F0.8330.96
427_V431_Y0.8330.96
20_T23_R0.8330.96
182_L600_I0.8330.96
374_V482_R0.8320.96
432_E435_L0.8320.96
186_F563_L0.8310.96
564_D567_Q0.8300.96
554_Q605_E0.8300.96
316_W319_K0.8290.96
384_I491_V0.8280.96
66_T69_G0.8270.96
362_L476_G0.8270.96
110_Y131_D0.8230.96
9_D12_K0.8220.96
239_V518_G0.8200.96
71_T131_D0.8190.96
516_L519_I0.8190.96
149_F205_I0.8180.96
349_K353_G0.8180.96
208_A223_Y0.8170.96
343_E547_W0.8160.96
153_K218_L0.8160.96
108_H112_E0.8160.96
261_C368_I0.8140.95
490_L494_V0.8130.95
260_V373_V0.8130.95
23_R169_A0.8120.95
238_T493_Y0.8120.95
19_Q23_R0.8090.95
454_L458_N0.8060.95
70_D98_E0.8040.95
143_R224_W0.8040.95
37_N49_K0.8020.95
386_G454_L0.8020.95
144_L224_W0.8010.95
53_V373_V0.7980.95
117_C140_A0.7970.95
106_L118_V0.7960.95
153_K158_F0.7960.95
349_K358_D0.7960.95
72_Y108_H0.7950.95
243_R276_I0.7930.95
450_A453_Q0.7930.95
242_V512_L0.7920.95
562_L604_F0.7900.95
85_D255_V0.7900.95
54_V101_S0.7900.95
507_R526_Y0.7900.95
575_E582_P0.7890.95
235_F511_I0.7890.95
211_L220_I0.7850.94
547_W551_I0.7840.94
164_I197_G0.7830.94
260_V374_V0.7830.94
357_V469_R0.7820.94
198_I351_L0.7820.94
457_L462_F0.7800.94
383_E388_Y0.7800.94
7_W159_L0.7800.94
82_N86_L0.7800.94
29_S478_S0.7790.94
541_T575_E0.7790.94
178_D181_G0.7780.94
379_E466_L0.7780.94
344_E347_L0.7750.94
235_F238_T0.7740.94
58_G101_S0.7730.94
343_E606_A0.7720.94
556_D559_L0.7710.94
246_F490_L0.7700.94
247_Q251_T0.7660.94
263_F365_C0.7640.94
27_T166_A0.7640.94
547_W598_A0.7630.94
244_S247_Q0.7620.94
574_T580_K0.7600.93
375_S474_S0.7580.93
20_T170_H0.7580.93
567_Q571_L0.7570.93
41_E44_V0.7570.93
261_C375_S0.7550.93
5_T28_L0.7540.93
558_V601_H0.7520.93
165_K347_L0.7520.93
87_R105_V0.7510.93
113_W117_C0.7500.93
467_L486_A0.7490.93
106_L129_V0.7480.93
292_Y372_F0.7460.93
34_D373_V0.7450.93
66_T95_H0.7440.93
127_F139_A0.7430.93
192_R195_G0.7430.93
242_V515_A0.7430.93
118_V223_Y0.7420.93
247_Q519_I0.7420.93
375_S481_V0.7410.93
556_D561_T0.7380.92
535_T539_E0.7380.92
71_T108_H0.7380.92
152_T202_I0.7350.92
143_R223_Y0.7340.92
522_D525_L0.7330.92
361_L470_K0.7310.92
319_K323_A0.7290.92
55_D58_G0.7270.92
468_D472_R0.7260.92
312_D315_P0.7260.92
317_I330_K0.7250.92
90_L113_W0.7250.92
573_E577_S0.7240.92
375_S479_L0.7240.92
35_D59_G0.7240.92
12_K17_E0.7240.92
238_T498_P0.7220.92
266_G293_S0.7190.91
360_S469_R0.7170.91
91_R100_T0.7150.91
115_E210_A0.7150.91
109_S120_H0.7140.91
357_V360_S0.7130.91
212_T219_N0.7120.91
457_L461_W0.7090.91
35_D75_I0.7080.91
249_A252_R0.7080.91
132_E135_N0.7080.91
239_V511_I0.7070.91
428_N432_E0.7070.91
236_D239_V0.7070.91
8_V213_F0.7060.91
368_I372_F0.7060.91
214_S219_N0.7050.91
75_I128_A0.7050.91
173_I202_I0.7030.91
191_S194_P0.7030.91
346_V599_Q0.7030.91
493_Y496_N0.7020.90
26_D29_S0.7010.90
151_Y211_L0.7010.90
164_I199_F0.7000.90
81_Y147_K0.7000.90
515_A519_I0.6990.90
413_L418_Q0.6980.90
86_L109_S0.6970.90
258_V373_V0.6960.90
404_R407_E0.6960.90
234_S238_T0.6960.90
24_M27_T0.6950.90
518_G525_L0.6940.90
39_W130_W0.6920.90
115_E118_V0.6900.90
66_T71_T0.6890.90
551_I602_T0.6890.90
520_L525_L0.6880.90
25_T29_S0.6870.90
361_L473_M0.6850.89
158_F211_L0.6840.89
559_L601_H0.6840.89
537_H581_V0.6840.89
77_N480_E0.6830.89
553_S569_D0.6820.89
64_A70_D0.6810.89
331_C367_E0.6780.89
149_F158_F0.6770.89
548_L572_L0.6750.89
264_L291_T0.6720.88
454_L457_L0.6700.88
361_L379_E0.6690.88
151_Y158_F0.6690.88
87_R91_R0.6690.88
367_E371_D0.6680.88
159_L173_I0.6680.88
329_H367_E0.6680.88
277_A376_L0.6670.88
455_F458_N0.6660.88
54_V99_R0.6660.88
575_E578_S0.6660.88
54_V84_E0.6640.88
157_S170_H0.6630.88
363_W366_R0.6620.88
391_F395_D0.6620.88
154_E159_L0.6610.88
199_F202_I0.6600.88
139_A158_F0.6590.87
530_S533_P0.6570.87
128_A211_L0.6560.87
91_R96_Q0.6550.87
168_L202_I0.6510.87
174_K201_G0.6500.87
72_Y134_R0.6500.87
574_T579_F0.6480.87
553_S557_S0.6450.86
384_I494_V0.6430.86
353_G379_E0.6430.86
345_A473_M0.6420.86
85_D88_K0.6420.86
153_K157_S0.6420.86
18_K38_V0.6420.86
189_G596_H0.6420.86
428_N431_Y0.6410.86
74_I118_V0.6410.86
65_C73_T0.6390.86
357_V379_E0.6380.86
9_D157_S0.6380.86
344_E348_V0.6380.86
259_P373_V0.6380.86
276_I280_H0.6380.86
233_D497_I0.6360.86
153_K156_S0.6360.86
42_H135_N0.6360.86
65_C95_H0.6360.86
153_K201_G0.6360.86
90_L97_F0.6350.86
227_E230_K0.6340.85
21_M24_M0.6340.85
546_E550_T0.6320.85
56_I257_D0.6310.85
244_S251_T0.6300.85
575_E594_I0.6280.85
53_V56_I0.6280.85
212_T221_W0.6280.85
147_K471_D0.6280.85
410_I418_Q0.6260.85
250_V276_I0.6250.85
203_K220_I0.6250.85
561_T601_H0.6250.85
99_R104_E0.6250.85
341_H359_S0.6240.85
295_D317_I0.6230.84
399_G403_M0.6220.84
516_L520_L0.6210.84
63_M99_R0.6210.84
323_A523_D0.6200.84
322_E325_G0.6190.84
109_S112_E0.6180.84
7_W170_H0.6170.84
64_A132_E0.6160.84
242_V511_I0.6150.84
362_L366_R0.6150.84
358_D469_R0.6150.84
412_L415_D0.6150.84
319_K524_I0.6140.84
234_S501_M0.6130.83
144_L458_N0.6130.83
107_L111_I0.6130.83
263_F375_S0.6120.83
600_I604_F0.6120.83
39_W44_V0.6110.83
268_L513_R0.6110.83
58_G100_T0.6100.83
130_W215_K0.6100.83
25_T45_L0.6090.83
86_L121_L0.6090.83
10_F217_G0.6080.83
451_R458_N0.6080.83
418_Q422_N0.6070.83
324_F328_H0.6040.83
39_W64_A0.6040.83
225_N455_F0.6030.82
494_V511_I0.6030.82
148_P162_S0.6020.82
9_D14_L0.5990.82
119_D221_W0.5990.82
454_L502_K0.5980.82
253_Q487_D0.5980.82
20_T169_A0.5970.82
451_R455_F0.5960.82
508_E513_R0.5960.82
276_I490_L0.5950.82
266_G527_R0.5950.82
397_E400_F0.5940.82
453_Q457_L0.5940.82
537_H541_T0.5940.82
344_E362_L0.5940.82
243_R516_L0.5940.82
2_C79_E0.5930.81
5_T21_M0.5930.81
434_T437_E0.5920.81
93_R96_Q0.5920.81
427_V435_L0.5910.81
74_I121_L0.5900.81
490_L493_Y0.5890.81
450_A457_L0.5880.81
314_G318_E0.5870.81
547_W602_T0.5870.81
511_I515_A0.5850.81
80_L83_T0.5850.81
293_S314_G0.5840.80
353_G357_V0.5840.80
562_L600_I0.5840.80
192_R204_E0.5830.80
361_L469_R0.5820.80
238_T241_N0.5820.80
27_T347_L0.5810.80
355_A361_L0.5810.80
290_H372_F0.5800.80
50_R55_D0.5800.80
22_D25_T0.5800.80
263_F355_A0.5790.80
393_T396_V0.5790.80
125_F143_R0.5780.80
70_D132_E0.5760.80
84_E88_K0.5750.79
84_E105_V0.5750.79
268_L516_L0.5740.79
564_D568_L0.5740.79
431_Y436_A0.5730.79
250_V277_A0.5730.79
150_F164_I0.5730.79
161_G167_I0.5720.79
56_I258_V0.5720.79
400_F403_M0.5710.79
66_T112_E0.5710.79
116_D221_W0.5710.79
380_C383_E0.5700.79
271_S527_R0.5690.79
97_F104_E0.5690.79
177_V198_I0.5680.79
60_R63_M0.5670.78
21_M40_G0.5670.78
74_I80_L0.5670.78
246_F273_I0.5670.78
242_V245_L0.5660.78
549_K553_S0.5660.78
63_M74_I0.5660.78
180_T200_K0.5660.78
511_I514_K0.5650.78
514_K526_Y0.5650.78
9_D156_S0.5650.78
48_H63_M0.5640.78
416_S419_K0.5640.78
258_V475_M0.5640.78
52_A99_R0.5640.78
432_E436_A0.5630.78
397_E401_P0.5620.78
63_M76_Y0.5610.78
18_K40_G0.5600.78
263_F469_R0.5590.77
354_M596_H0.5580.77
165_K348_V0.5580.77
471_D480_E0.5580.77
523_D526_Y0.5580.77
392_H395_D0.5570.77
548_L551_I0.5550.77
23_R26_D0.5550.77
197_G202_I0.5540.77
513_R526_Y0.5540.77
54_V58_G0.5540.77
262_T273_I0.5540.77
275_A520_L0.5530.77
179_R200_K0.5530.77
191_S198_I0.5530.77
234_S240_A0.5530.77
507_R510_G0.5530.77
96_Q108_H0.5520.77
429_A433_E0.5520.77
391_F394_A0.5510.76
426_Y431_Y0.5510.76
7_W17_E0.5500.76
124_I483_V0.5500.76
381_A533_P0.5480.76
143_R492_E0.5480.76
58_G99_R0.5470.76
422_N425_E0.5470.76
413_L416_S0.5470.76
466_L470_K0.5460.76
414_S418_Q0.5440.76
398_S402_W0.5430.75
452_R456_Y0.5430.75
501_M510_G0.5420.75
312_D332_V0.5420.75
545_S569_D0.5420.75
131_D136_L0.5420.75
537_H583_W0.5420.75
204_E464_T0.5410.75
339_V544_V0.5410.75
291_T330_K0.5400.75
377_S461_W0.5400.75
33_P51_L0.5400.75
48_H61_Q0.5390.75
159_L172_D0.5390.75
404_R409_R0.5380.75
213_F217_G0.5380.75
527_R530_S0.5360.75
110_Y114_Q0.5360.75
349_K468_D0.5350.74
10_F13_Q0.5340.74
467_L471_D0.5340.74
238_T511_I0.5340.74
435_L438_T0.5340.74
372_F479_L0.5330.74
85_D122_N0.5330.74
266_G316_W0.5320.74
17_E20_T0.5310.74
280_H289_L0.5310.74
457_L465_N0.5310.74
144_L490_L0.5310.74
399_G402_W0.5300.74
248_D488_H0.5300.74
597_L601_H0.5290.74
2_C53_V0.5290.74
83_T99_R0.5290.74
83_T97_F0.5280.73
450_A454_L0.5280.73
382_D509_K0.5280.73
162_S480_E0.5270.73
48_H76_Y0.5260.73
163_E350_D0.5260.73
457_L463_M0.5260.73
77_N388_Y0.5250.73
65_C107_L0.5250.73
84_E252_R0.5240.73
107_L129_V0.5240.73
361_L533_P0.5240.73
356_D536_H0.5230.73
411_K414_S0.5230.73
161_G170_H0.5230.73
7_W20_T0.5230.73
151_Y220_I0.5220.73
554_Q601_H0.5220.73
461_W465_N0.5210.72
321_T326_T0.5210.72
57_E60_R0.5210.72
459_M462_F0.5210.72
540_Y548_L0.5200.72
226_V495_W0.5190.72
180_T195_G0.5190.72
263_F377_S0.5180.72
582_P593_L0.5180.72
268_L508_E0.5170.72
51_L77_N0.5170.72
571_L593_L0.5170.72
583_W592_Q0.5160.72
507_R514_K0.5160.72
263_F479_L0.5160.72
152_T155_G0.5160.72
154_E201_G0.5150.72
345_A362_L0.5140.71
516_L525_L0.5130.71
66_T98_E0.5130.71
225_N443_G0.5120.71
379_E461_W0.5120.71
462_F465_N0.5120.71
571_L582_P0.5120.71
269_D509_K0.5120.71
2_C50_R0.5110.71
424_K427_V0.5110.71
8_V43_H0.5110.71
467_L483_V0.5110.71
146_V488_H0.5100.71
77_N147_K0.5100.71
383_E529_K0.5090.71
48_H103_T0.5090.71
69_G72_Y0.5090.71
146_V468_D0.5090.71
379_E483_V0.5080.71
544_V548_L0.5070.70
244_S248_D0.5070.70
75_I160_F0.5070.70
64_A71_T0.5070.70
344_E476_G0.5070.70
521_P524_I0.5060.70
246_F512_L0.5060.70
572_L576_G0.5050.70
230_K496_N0.5050.70
58_G63_M0.5040.70
181_G195_G0.5040.70
190_P465_N0.5030.70
213_F216_D0.5030.70
342_L599_Q0.5020.70
194_P206_R0.5020.70
356_D360_S0.5010.70
7_W157_S0.5010.70
320_M324_F0.5000.69
85_D248_D0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ct9A 2 0.7866 100 0.301 Contact Map
1q15A 3 0.7785 100 0.305 Contact Map
1jgtA 2 0.7704 100 0.322 Contact Map
1ao0A 3 0.6515 100 0.69 Contact Map
1xffA 2 0.3225 100 0.716 Contact Map
1te5A 2 0.3046 100 0.723 Contact Map
4amvA 2 0.8274 100 0.73 Contact Map
1ecfA 4 0.6564 100 0.732 Contact Map
3mdnA 4 0.2704 100 0.757 Contact Map
4zflA 5 0.2964 100 0.781 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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