RHAB - BACSU - GREMLIN Contacts

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RHAB - Rhamnulokinase

UniProt:	O05262	Sequences: MIYTAIDVGASSGRIMVGELNEGKLDIQEIHRFANGFSQRDGHCLWDIDHLLKQILQGLQKVKTLGYEHCTVGIDTWAVDYVLLDEKGDRLREAISYRDRRTDHTIDKLEHTLSKAAIYQKTGIQFQPFNTIYQLFEEDRELLKKTDKIMMIPDYLGYCLTGKAVTEITNVSTTQLLNVSTGNLDPELLEAVSVLEQQFAPLTEPGCELGKLRNEWFPDYDLPACKVMTVATHDTASAVIAAPGVNDGWAYISSGTWSLIGVENKTPIITDLALENNYTNERGANNTIRFLKNIIGMWVIQEVKQQLQADYSFQQLAEEAKKTEPFQQFINLNDKRFLNPENMIKEIQHYCRQTRQKIPRTAGELACCIYSNLAIIYAIAIKELETITEKPIEQFHIIGGGARNDFLNQLTADMSGKAVYAGPIEATATGNLLMQMIAAKEVKDIKEARQVVRNSFPIKVFTPKDIDRSTIIQSFQQTVLKALSK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	485 (464)
Sequences:	12518 (8632)
Seq/√Len:	400.7

ECOLI - LYXK RHAB XYLB ARAB LSRK FUCK GLPK YGCE
BACSU - RHAB XYLB GNTK ARAB YOAC GLPK
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
186_P	196_E	4.302	1.00
105_T	137_E	3.742	1.00
19_E	23_G	3.678	1.00
15_I	58_G	3.446	1.00
378_A	472_I	3.203	1.00
108_K	137_E	3.154	1.00
378_A	382_K	2.973	1.00
178_N	181_T	2.933	1.00
418_A	462_T	2.916	1.00
121_K	185_D	2.897	1.00
385_E	417_K	2.840	1.00
91_L	142_L	2.814	1.00
323_T	364_E	2.814	1.00
409_Q	413_D	2.785	1.00
353_Q	365_L	2.772	1.00
177_L	202_L	2.752	1.00
37_F	93_E	2.721	1.00
405_D	459_K	2.720	1.00
394_Q	420_Y	2.685	1.00
163_K	201_P	2.680	1.00
17_V	62_V	2.636	1.00
443_K	447_E	2.632	1.00
204_E	207_C	2.592	1.00
444_D	447_E	2.568	1.00
52_L	159_C	2.549	1.00
92_R	139_D	2.506	1.00
86_E	147_D	2.473	1.00
183_N	196_E	2.452	1.00
49_D	159_C	2.449	1.00
85_D	145_K	2.409	1.00
178_N	185_D	2.389	1.00
189_L	196_E	2.332	1.00
312_S	315_Q	2.250	1.00
186_P	190_E	2.235	1.00
232_T	237_S	2.206	1.00
157_G	231_A	2.158	1.00
16_M	428_A	2.155	1.00
6_I	55_I	2.151	1.00
148_K	164_A	2.114	1.00
464_K	467_D	2.110	1.00
31_H	61_K	2.065	1.00
299_V	369_I	2.063	1.00
31_H	57_Q	2.044	1.00
213_R	216_W	2.041	1.00
49_D	89_D	2.024	1.00
108_K	112_T	2.018	1.00
117_A	120_Q	1.968	1.00
328_Q	364_E	1.965	1.00
416_G	468_R	1.953	1.00
61_K	65_L	1.946	1.00
322_K	363_G	1.932	1.00
361_T	364_E	1.927	1.00
40_R	43_H	1.925	1.00
385_E	391_P	1.920	1.00
4_T	59_L	1.907	1.00
161_T	228_M	1.903	1.00
3_Y	436_M	1.889	1.00
258_S	296_G	1.885	1.00
397_I	408_N	1.885	1.00
311_Y	315_Q	1.880	1.00
4_T	15_I	1.878	1.00
29_E	61_K	1.850	1.00
214_N	224_A	1.846	1.00
8_V	13_G	1.838	1.00
315_Q	318_E	1.794	1.00
229_T	438_A	1.778	1.00
203_T	207_C	1.776	1.00
303_V	369_I	1.735	1.00
249_W	394_Q	1.729	1.00
121_K	187_E	1.724	1.00
85_D	89_D	1.722	1.00
208_E	211_K	1.720	1.00
12_S	30_I	1.716	1.00
88_G	158_Y	1.705	1.00
117_A	187_E	1.702	1.00
420_Y	460_V	1.696	1.00
117_A	121_K	1.686	1.00
413_D	464_K	1.680	1.00
165_V	203_T	1.679	1.00
107_D	111_H	1.670	1.00
418_A	460_V	1.662	1.00
472_I	476_Q	1.662	1.00
104_H	108_K	1.654	1.00
301_Q	305_Q	1.643	1.00
208_E	229_T	1.641	1.00
319_E	363_G	1.632	1.00
265_K	285_N	1.621	1.00
82_V	152_I	1.615	1.00
83_L	198_Q	1.613	1.00
110_E	115_K	1.601	1.00
350_Y	357_K	1.579	1.00
319_E	322_K	1.575	1.00
180_S	267_P	1.569	1.00
3_Y	441_E	1.548	1.00
413_D	467_D	1.515	1.00
63_K	66_G	1.506	1.00
47_D	50_H	1.503	1.00
141_E	144_K	1.499	1.00
382_K	385_E	1.498	1.00
223_P	226_K	1.491	1.00
157_G	209_L	1.458	1.00
20_L	441_E	1.451	1.00
436_M	442_V	1.448	1.00
116_A	120_Q	1.446	1.00
318_E	322_K	1.434	1.00
161_T	210_G	1.427	1.00
52_L	56_L	1.412	1.00
195_L	198_Q	1.409	1.00
34_A	50_H	1.408	1.00
405_D	421_A	1.403	1.00
49_D	53_K	1.399	1.00
330_I	474_S	1.393	1.00
468_R	472_I	1.393	1.00
319_E	362_A	1.385	1.00
367_C	371_S	1.381	1.00
316_L	366_A	1.380	1.00
320_A	406_F	1.376	1.00
84_L	150_M	1.372	1.00
406_F	410_L	1.368	1.00
247_D	265_K	1.365	1.00
374_A	410_L	1.359	1.00
211_K	225_C	1.339	1.00
6_I	59_L	1.338	1.00
71_T	435_Q	1.337	1.00
250_A	392_I	1.333	1.00
189_L	199_F	1.324	1.00
155_Y	159_C	1.321	1.00
103_D	107_D	1.319	1.00
78_A	233_H	1.314	1.00
254_S	411_T	1.313	1.00
394_Q	418_A	1.306	1.00
405_D	461_F	1.286	1.00
375_I	474_S	1.285	1.00
13_G	55_I	1.281	1.00
139_D	142_L	1.280	1.00
168_I	182_G	1.277	1.00
317_A	321_K	1.275	1.00
315_Q	319_E	1.265	1.00
374_A	414_M	1.264	1.00
374_A	411_T	1.264	1.00
252_I	411_T	1.262	1.00
22_E	26_D	1.255	1.00
105_T	136_F	1.255	1.00
26_D	65_L	1.251	1.00
465_D	468_R	1.250	1.00
403_R	424_I	1.250	1.00
117_A	191_A	1.248	1.00
112_T	191_A	1.239	1.00
421_A	461_F	1.236	1.00
157_G	165_V	1.233	1.00
203_T	209_L	1.232	1.00
378_A	475_F	1.230	1.00
13_G	54_Q	1.228	1.00
232_T	434_M	1.227	1.00
326_F	329_F	1.227	1.00
163_K	203_T	1.226	1.00
118_I	126_F	1.218	1.00
132_I	192_V	1.217	1.00
53_K	57_Q	1.216	1.00
246_N	449_R	1.216	1.00
88_G	164_A	1.206	1.00
208_E	227_V	1.204	1.00
408_N	461_F	1.200	1.00
80_D	94_A	1.192	1.00
26_D	62_V	1.189	1.00
45_L	93_E	1.181	1.00
307_L	365_L	1.179	1.00
290_F	294_I	1.177	1.00
6_I	15_I	1.177	1.00
378_A	415_S	1.173	1.00
314_Q	317_A	1.172	1.00
187_E	190_E	1.169	1.00
295_I	299_V	1.167	1.00
29_E	58_G	1.161	1.00
416_G	472_I	1.157	1.00
410_L	414_M	1.154	1.00
246_N	249_W	1.147	1.00
37_F	50_H	1.144	1.00
83_L	146_T	1.139	1.00
317_A	405_D	1.138	1.00
55_I	156_L	1.134	1.00
143_L	146_T	1.133	1.00
47_D	93_E	1.130	1.00
165_V	209_L	1.129	1.00
208_E	438_A	1.128	1.00
356_Q	360_R	1.124	1.00
318_E	321_K	1.123	1.00
57_Q	61_K	1.122	1.00
104_H	107_D	1.121	1.00
150_M	164_A	1.121	1.00
106_I	126_F	1.118	1.00
317_A	404_N	1.117	1.00
295_I	298_W	1.116	1.00
168_I	202_L	1.114	1.00
120_Q	269_I	1.105	1.00
28_Q	65_L	1.103	1.00
447_E	450_Q	1.101	1.00
168_I	177_L	1.097	1.00
249_W	396_H	1.097	1.00
332_L	337_F	1.097	1.00
329_F	332_L	1.092	1.00
464_K	468_R	1.092	1.00
332_L	353_Q	1.088	1.00
246_N	446_K	1.084	1.00
29_E	62_V	1.081	1.00
146_T	198_Q	1.070	1.00
71_T	439_A	1.070	1.00
360_R	364_E	1.067	1.00
48_I	82_V	1.067	1.00
3_Y	439_A	1.066	1.00
51_L	152_I	1.064	1.00
469_S	473_Q	1.062	1.00
396_H	420_Y	1.060	1.00
72_V	226_K	1.053	1.00
471_I	474_S	1.052	1.00
475_F	478_T	1.049	1.00
375_I	414_M	1.047	1.00
18_G	432_L	1.044	1.00
107_D	110_E	1.041	1.00
475_F	479_V	1.039	1.00
141_E	145_K	1.039	1.00
319_E	366_A	1.038	1.00
18_G	24_K	1.035	1.00
83_L	135_L	1.034	1.00
351_C	356_Q	1.031	1.00
74_I	157_G	1.023	1.00
250_A	262_V	1.022	1.00
394_Q	460_V	1.022	1.00
61_K	64_T	1.013	1.00
50_H	53_K	1.012	1.00
293_N	376_I	1.011	1.00
105_T	138_E	1.011	1.00
381_I	415_S	1.010	1.00
437_I	448_A	1.010	1.00
158_Y	164_A	1.007	1.00
60_Q	64_T	1.003	1.00
55_I	59_L	1.003	1.00
15_I	62_V	1.001	1.00
92_R	142_L	0.999	1.00
44_C	98_R	0.997	1.00
105_T	108_K	0.994	1.00
378_A	414_M	0.990	1.00
373_L	401_G	0.990	1.00
75_D	427_T	0.987	1.00
34_A	37_F	0.985	1.00
36_G	46_W	0.983	1.00
474_S	477_Q	0.982	1.00
367_C	406_F	0.979	1.00
83_L	149_I	0.978	1.00
436_M	441_E	0.977	1.00
375_I	471_I	0.976	1.00
56_L	60_Q	0.974	1.00
17_V	69_H	0.971	1.00
71_T	229_T	0.971	1.00
108_K	111_H	0.965	1.00
248_G	393_E	0.962	1.00
132_I	175_Q	0.956	1.00
140_R	144_K	0.955	1.00
321_K	406_F	0.955	1.00
251_Y	398_I	0.954	1.00
131_T	134_Q	0.951	1.00
70_C	439_A	0.946	1.00
433_L	448_A	0.943	1.00
30_I	33_F	0.942	1.00
211_K	227_V	0.940	1.00
401_G	407_L	0.939	1.00
63_K	69_H	0.938	1.00
4_T	17_V	0.938	1.00
260_I	381_I	0.936	1.00
177_L	181_T	0.935	1.00
108_K	136_F	0.934	1.00
18_G	429_T	0.934	1.00
142_L	145_K	0.933	1.00
182_G	204_E	0.933	1.00
89_D	159_C	0.927	1.00
180_S	269_I	0.922	1.00
189_L	194_V	0.920	1.00
356_Q	365_L	0.918	1.00
229_T	439_A	0.915	1.00
118_I	175_Q	0.913	1.00
472_I	475_F	0.912	1.00
81_Y	149_I	0.909	1.00
288_I	292_K	0.908	1.00
74_I	156_L	0.907	1.00
469_S	472_I	0.905	1.00
120_Q	180_S	0.904	1.00
395_F	415_S	0.904	1.00
114_S	191_A	0.903	1.00
166_T	171_V	0.902	1.00
162_G	213_R	0.897	1.00
246_N	393_E	0.890	1.00
67_Y	223_P	0.888	1.00
8_V	156_L	0.888	1.00
135_L	149_I	0.887	1.00
4_T	69_H	0.877	1.00
258_S	377_Y	0.873	1.00
168_I	204_E	0.872	1.00
147_D	197_Q	0.871	1.00
203_T	230_V	0.866	1.00
73_G	229_T	0.865	1.00
459_K	463_P	0.863	1.00
433_L	452_V	0.862	1.00
336_R	353_Q	0.862	1.00
146_T	149_I	0.861	1.00
8_V	55_I	0.859	1.00
74_I	160_L	0.859	1.00
165_V	201_P	0.857	1.00
415_S	418_A	0.856	1.00
154_D	166_T	0.856	1.00
310_D	316_L	0.853	1.00
137_E	140_R	0.853	1.00
272_L	386_T	0.849	1.00
382_K	472_I	0.849	1.00
21_N	451_V	0.847	1.00
353_Q	369_I	0.847	1.00
382_K	386_T	0.846	1.00
183_N	201_P	0.846	1.00
308_Q	362_A	0.845	1.00
410_L	471_I	0.844	1.00
69_H	226_K	0.843	1.00
422_G	454_N	0.843	1.00
437_I	444_D	0.838	1.00
79_V	173_T	0.833	1.00
313_F	316_L	0.828	1.00
100_R	127_Q	0.828	1.00
59_L	63_K	0.827	1.00
177_L	182_G	0.827	1.00
470_T	474_S	0.823	1.00
314_Q	318_E	0.822	1.00
246_N	450_Q	0.821	1.00
238_A	398_I	0.817	1.00
114_S	117_A	0.817	1.00
106_I	133_Y	0.815	1.00
168_I	281_E	0.815	1.00
171_V	184_L	0.815	1.00
214_N	225_C	0.813	1.00
70_C	441_E	0.812	1.00
212_L	226_K	0.809	1.00
84_L	88_G	0.808	1.00
290_F	293_N	0.808	1.00
320_A	367_C	0.807	1.00
180_S	266_T	0.804	1.00
211_K	224_A	0.802	1.00
397_I	411_T	0.801	1.00
381_I	385_E	0.799	1.00
473_Q	476_Q	0.799	1.00
110_E	126_F	0.798	1.00
151_M	174_T	0.795	1.00
48_I	93_E	0.795	1.00
422_G	453_R	0.794	1.00
252_I	377_Y	0.793	1.00
349_H	352_R	0.793	1.00
130_N	134_Q	0.793	1.00
437_I	445_I	0.793	1.00
19_E	25_L	0.791	1.00
281_E	286_N	0.790	1.00
262_V	384_L	0.790	1.00
326_F	330_I	0.789	1.00
132_I	176_L	0.786	1.00
370_Y	410_L	0.785	1.00
402_A	424_I	0.783	1.00
91_L	145_K	0.782	1.00
466_I	469_S	0.780	1.00
136_F	193_S	0.779	1.00
56_L	216_W	0.779	1.00
32_R	61_K	0.778	1.00
166_T	200_A	0.778	1.00
250_A	395_F	0.777	1.00
166_T	202_L	0.776	1.00
135_L	176_L	0.776	1.00
303_V	366_A	0.775	1.00
31_H	34_A	0.775	1.00
183_N	186_P	0.774	1.00
442_V	448_A	0.773	1.00
187_E	191_A	0.772	1.00
370_Y	404_N	0.769	1.00
78_A	170_N	0.769	1.00
39_Q	43_H	0.768	1.00
5_A	73_G	0.768	1.00
332_L	369_I	0.763	1.00
463_P	468_R	0.763	1.00
104_H	138_E	0.761	1.00
304_K	313_F	0.761	1.00
235_T	259_L	0.757	1.00
33_F	54_Q	0.757	1.00
409_Q	464_K	0.757	1.00
242_A	251_Y	0.756	1.00
3_Y	71_T	0.754	1.00
184_L	199_F	0.753	1.00
242_A	398_I	0.752	1.00
84_L	164_A	0.752	1.00
321_K	409_Q	0.750	1.00
397_I	421_A	0.750	1.00
402_A	408_N	0.749	1.00
31_H	58_G	0.747	1.00
190_E	196_E	0.747	1.00
252_I	258_S	0.745	1.00
50_H	54_Q	0.744	1.00
88_G	147_D	0.741	1.00
121_K	178_N	0.741	1.00
374_A	407_L	0.740	1.00
85_D	91_L	0.740	1.00
452_V	455_S	0.739	1.00
10_A	96_S	0.739	1.00
45_L	101_R	0.738	1.00
302_E	305_Q	0.735	1.00
18_G	423_P	0.735	1.00
169_T	280_N	0.733	1.00
122_T	188_L	0.732	1.00
323_T	363_G	0.732	1.00
340_P	343_M	0.729	1.00
265_K	287_T	0.729	1.00
153_P	231_A	0.728	1.00
382_K	479_V	0.727	1.00
326_F	371_S	0.727	1.00
49_D	155_Y	0.726	1.00
124_I	130_N	0.724	1.00
72_V	212_L	0.724	1.00
53_K	56_L	0.723	1.00
288_I	293_N	0.721	1.00
382_K	476_Q	0.721	1.00
169_T	232_T	0.719	1.00
185_D	188_L	0.716	1.00
303_V	365_L	0.715	1.00
106_I	128_P	0.715	1.00
383_E	386_T	0.714	1.00
472_I	478_T	0.713	1.00
321_K	405_D	0.712	1.00
83_L	91_L	0.712	1.00
104_H	137_E	0.710	1.00
71_T	227_V	0.710	1.00
422_G	455_S	0.708	1.00
52_L	216_W	0.707	1.00
109_L	192_V	0.707	1.00
222_L	226_K	0.707	1.00
56_L	159_C	0.706	1.00
8_V	54_Q	0.705	1.00
59_L	62_V	0.705	1.00
97_Y	257_W	0.703	1.00
447_E	451_V	0.703	1.00
244_G	251_Y	0.703	1.00
238_A	427_T	0.701	1.00
95_I	101_R	0.700	1.00
155_Y	158_Y	0.699	1.00
157_G	161_T	0.699	1.00
448_A	452_V	0.699	1.00
49_D	90_R	0.697	1.00
118_I	188_L	0.696	1.00
382_K	475_F	0.696	1.00
320_A	366_A	0.693	1.00
85_D	147_D	0.693	1.00
224_A	227_V	0.691	1.00
436_M	440_K	0.690	1.00
178_N	183_N	0.690	1.00
291_L	294_I	0.689	1.00
323_T	326_F	0.688	1.00
212_L	222_L	0.686	1.00
78_A	291_L	0.684	1.00
442_V	451_V	0.684	1.00
209_L	230_V	0.681	0.99
296_G	373_L	0.679	0.99
16_M	24_K	0.678	0.99
446_K	449_R	0.678	0.99
222_L	225_C	0.677	0.99
86_E	145_K	0.677	0.99
397_I	419_V	0.677	0.99
393_E	417_K	0.676	0.99
350_Y	354_T	0.675	0.99
346_E	349_H	0.674	0.99
379_I	479_V	0.674	0.99
448_A	451_V	0.673	0.99
394_Q	417_K	0.672	0.99
107_D	348_Q	0.671	0.99
252_I	395_F	0.670	0.99
129_F	134_Q	0.668	0.99
84_L	158_Y	0.668	0.99
473_Q	477_Q	0.668	0.99
32_R	301_Q	0.667	0.99
332_L	368_C	0.666	0.99
461_F	468_R	0.664	0.99
449_R	452_V	0.663	0.99
234_D	256_T	0.662	0.99
311_Y	362_A	0.660	0.99
371_S	410_L	0.659	0.99
317_A	406_F	0.653	0.99
301_Q	313_F	0.651	0.99
204_E	281_E	0.651	0.99
462_T	465_D	0.650	0.99
216_W	225_C	0.648	0.99
395_F	419_V	0.645	0.99
265_K	286_N	0.645	0.99
66_G	69_H	0.645	0.99
144_K	148_K	0.644	0.99
288_I	294_I	0.643	0.99
300_I	317_A	0.643	0.99
301_Q	304_K	0.642	0.99
449_R	453_R	0.642	0.99
325_P	329_F	0.641	0.99
344_I	379_I	0.641	0.99
288_I	291_L	0.641	0.99
395_F	417_K	0.641	0.99
433_L	451_V	0.640	0.99
325_P	470_T	0.640	0.99
465_D	469_S	0.639	0.99
205_P	231_A	0.639	0.99
323_T	328_Q	0.639	0.99
76_T	170_N	0.637	0.99
330_I	360_R	0.636	0.99
57_Q	60_Q	0.633	0.99
409_Q	461_F	0.631	0.99
18_G	428_A	0.630	0.99
336_R	340_P	0.629	0.99
211_K	214_N	0.628	0.99
297_M	301_Q	0.627	0.99
323_T	327_Q	0.625	0.99
208_E	439_A	0.625	0.99
405_D	409_Q	0.624	0.99
55_I	58_G	0.622	0.99
258_S	411_T	0.622	0.99
84_L	155_Y	0.621	0.99
136_F	192_V	0.620	0.99
33_F	46_W	0.619	0.99
182_G	281_E	0.619	0.99
84_L	148_K	0.618	0.99
154_D	164_A	0.618	0.99
133_Y	175_Q	0.617	0.99
467_D	471_I	0.616	0.99
176_L	199_F	0.612	0.99
437_I	442_V	0.611	0.99
416_G	465_D	0.611	0.99
264_N	268_I	0.610	0.99
153_P	170_N	0.608	0.99
143_L	147_D	0.608	0.99
244_G	249_W	0.608	0.99
136_F	143_L	0.607	0.99
49_D	93_E	0.606	0.99
182_G	286_N	0.606	0.99
29_E	65_L	0.606	0.99
113_L	188_L	0.604	0.99
323_T	367_C	0.604	0.99
303_V	307_L	0.604	0.99
227_V	439_A	0.601	0.99
409_Q	412_A	0.601	0.99
338_L	358_I	0.601	0.99
267_P	276_N	0.600	0.99
77_W	97_Y	0.600	0.99
418_A	463_P	0.600	0.99
76_T	152_I	0.598	0.99
404_N	407_L	0.598	0.99
201_P	207_C	0.597	0.99
331_N	353_Q	0.597	0.99
145_K	148_K	0.596	0.99
233_H	236_A	0.596	0.99
332_L	372_N	0.595	0.99
433_L	437_I	0.594	0.99
320_A	370_Y	0.591	0.99
190_E	195_L	0.591	0.99
476_Q	479_V	0.590	0.99
29_E	33_F	0.589	0.99
339_N	343_M	0.588	0.98
143_L	193_S	0.588	0.98
89_D	145_K	0.587	0.98
320_A	323_T	0.586	0.98
371_S	375_I	0.586	0.98
287_T	290_F	0.586	0.98
20_L	70_C	0.585	0.98
303_V	308_Q	0.585	0.98
194_V	199_F	0.584	0.98
118_I	192_V	0.584	0.98
367_C	410_L	0.584	0.98
128_P	347_I	0.583	0.98
243_P	449_R	0.583	0.98
102_T	133_Y	0.581	0.98
31_H	54_Q	0.580	0.98
69_H	222_L	0.580	0.98
313_F	317_A	0.578	0.98
56_L	59_L	0.578	0.98
81_Y	131_T	0.578	0.98
326_F	367_C	0.577	0.98
190_E	193_S	0.577	0.98
49_D	52_L	0.577	0.98
212_L	221_D	0.576	0.98
241_A	426_A	0.575	0.98
135_L	198_Q	0.574	0.98
116_A	119_Y	0.574	0.98
126_F	175_Q	0.571	0.98
467_D	470_T	0.571	0.98
103_D	128_P	0.571	0.98
416_G	467_D	0.571	0.98
235_T	253_S	0.570	0.98
83_L	92_R	0.569	0.98
474_S	478_T	0.569	0.98
280_N	283_G	0.568	0.98
3_Y	442_V	0.568	0.98
43_H	101_R	0.567	0.98
212_L	223_P	0.566	0.98
60_Q	63_K	0.565	0.98
392_I	417_K	0.565	0.98
408_N	421_A	0.565	0.98
48_I	94_A	0.565	0.98
317_A	370_Y	0.563	0.98
47_D	53_K	0.563	0.98
28_Q	425_E	0.562	0.98
169_T	205_P	0.562	0.98
82_V	94_A	0.562	0.98
88_G	148_K	0.560	0.98
32_R	304_K	0.559	0.98
414_M	471_I	0.559	0.98
260_I	380_A	0.559	0.98
78_A	173_T	0.557	0.98
252_I	260_I	0.557	0.98
45_L	92_R	0.556	0.98
213_R	225_C	0.556	0.98
306_Q	361_T	0.556	0.98
19_E	22_E	0.556	0.98
133_Y	136_F	0.555	0.98
446_K	450_Q	0.555	0.98
143_L	195_L	0.554	0.98
82_V	90_R	0.554	0.98
206_G	438_A	0.553	0.98
329_F	360_R	0.552	0.98
317_A	320_A	0.552	0.98
239_V	261_G	0.551	0.98
373_L	407_L	0.551	0.98
180_S	183_N	0.550	0.98
174_T	184_L	0.549	0.98
10_A	97_Y	0.548	0.98
254_S	397_I	0.546	0.98
461_F	465_D	0.546	0.98
325_P	328_Q	0.544	0.98
285_N	288_I	0.543	0.97
90_R	93_E	0.542	0.97
72_V	228_M	0.542	0.97
163_K	211_K	0.542	0.97
216_W	222_L	0.541	0.97
471_I	478_T	0.540	0.97
24_K	28_Q	0.539	0.97
325_P	367_C	0.539	0.97
240_I	433_L	0.538	0.97
51_L	94_A	0.537	0.97
11_S	14_R	0.537	0.97
188_L	192_V	0.537	0.97
243_P	452_V	0.536	0.97
402_A	421_A	0.533	0.97
429_T	433_L	0.533	0.97
411_T	415_S	0.530	0.97
459_K	468_R	0.529	0.97
412_A	419_V	0.528	0.97
16_M	429_T	0.528	0.97
43_H	95_I	0.528	0.97
54_Q	57_Q	0.527	0.97
109_L	133_Y	0.527	0.97
277_N	289_R	0.526	0.97
300_I	316_L	0.525	0.97
253_S	398_I	0.525	0.97
188_L	191_A	0.524	0.97
470_T	473_Q	0.524	0.97
428_A	431_N	0.524	0.97
332_L	335_K	0.523	0.97
444_D	448_A	0.523	0.97
249_W	393_E	0.521	0.97
287_T	445_I	0.520	0.97
169_T	236_A	0.520	0.97
3_Y	70_C	0.520	0.97
26_D	29_E	0.520	0.97
342_N	345_K	0.519	0.97
68_E	223_P	0.519	0.97
84_L	147_D	0.518	0.97
80_D	96_S	0.518	0.97
38_S	44_C	0.518	0.97
440_K	443_K	0.517	0.97
44_C	96_S	0.517	0.97
445_I	449_R	0.517	0.97
472_I	479_V	0.516	0.97
150_M	158_Y	0.516	0.97
262_V	392_I	0.516	0.97
168_I	205_P	0.515	0.97
162_G	215_E	0.515	0.97
319_E	323_T	0.514	0.97
77_W	94_A	0.512	0.96
123_G	134_Q	0.510	0.96
327_Q	364_E	0.510	0.96
234_D	400_G	0.509	0.96
75_D	431_N	0.508	0.96
393_E	418_A	0.508	0.96
316_L	404_N	0.507	0.96
151_M	170_N	0.506	0.96
324_E	364_E	0.505	0.96
230_V	237_S	0.505	0.96
118_I	191_A	0.503	0.96
79_V	97_Y	0.503	0.96
240_I	445_I	0.502	0.96
249_W	449_R	0.502	0.96
437_I	440_K	0.502	0.96
24_K	423_P	0.500	0.96
253_S	259_L	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ll3A	2	0.9814	100	0.13	Contact Map
3hz6A	1	0.9753	100	0.143	Contact Map
2itmA	2	0.9546	100	0.147	Contact Map
3ifrA	2	0.9711	100	0.151	Contact Map
3qdkA	2	0.9856	100	0.155	Contact Map
3wxlA	2	0.9897	100	0.158	Contact Map
3ezwA	3	0.9753	100	0.168	Contact Map
2w40A	3	0.9753	100	0.173	Contact Map
3h3nX	3	0.9753	100	0.174	Contact Map
2d4wA	2	0.9732	100	0.175	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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