YUFO - BACSU - GREMLIN Contacts

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YUFO - Uncharacterized ABC transporter ATP-binding protein YufO

UniProt:	O05253	Sequences: MEYVIEMLNIRKAFPGIVANDNINLQVKKGEIHALLGENGAGKSTLMNVLFGLYQPERGEIRVRGEKVHINSPNKANDLGIGMVHQHFMLVDTFTVAENIILGKEPKKFGRIDRKRAGQEVQDISDRYGLQIHPEAKAADISVGMQQRAEILKTLYRGADILIFDEPTAVLTPHEIKELMQIMKNLVKEGKSIILITHKLKEIMEICDRVTVIRKGKGIKTLDVRDTNQDELASLMVGREVSFKTEKRAAQPGAEVLAIDGITVKDTRGIETVRDLSLSVKAGEIVGIAGVDGNGQSELIEAVTGLRKTDSGTITLNGKQIQNLTPRKITESGIGHIPQDRHKHGLVLDFPIGENILLQSYYKKPYSALGVLHKGEMYKKARSLITEYDVRTPDEYTHARALSGGNQQKAIIGREIDRNPDLLIAAQPTRGLDVGAIEFVHKKLIEQRDAGKAVLLLSFELEEIMNLSDRIAVIFEGRIIASVNPQETTEQELGLLMAGSTQKEAGKANG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	510 (477)
Sequences:	9832 (6530)
Seq/√Len:	299.0

ECOLI - MGLA XYLG ALSA YPHE YTFR ARAG LSRA RBSA YEJF MODF
BACSU - YUFO RBSA YKPA YFMM YKOD
HALSA - Q9HR21
SULSO - Y2030 Y1893

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
60_E	67_K	3.450	1.00
21_D	217_K	3.444	1.00
31_E	209_R	3.315	1.00
33_H	211_T	3.136	1.00
118_G	135_E	3.120	1.00
317_N	421_D	3.113	1.00
258_A	279_S	3.096	1.00
313_T	320_Q	3.055	1.00
14_F	54_Y	3.050	1.00
385_I	395_E	3.039	1.00
64_R	160_D	2.997	1.00
301_E	307_R	2.848	1.00
258_A	315_T	2.817	1.00
9_N	22_N	2.799	1.00
34_A	207_C	2.777	1.00
261_G	275_D	2.760	1.00
260_D	313_T	2.753	1.00
116_R	120_E	2.719	1.00
220_K	235_L	2.709	1.00
122_Q	126_D	2.642	1.00
136_A	140_D	2.553	1.00
255_E	258_A	2.540	1.00
13_A	18_V	2.538	1.00
6_E	62_R	2.510	1.00
6_E	26_Q	2.477	1.00
300_I	457_L	2.462	1.00
184_K	205_E	2.440	1.00
254_A	282_A	2.408	1.00
8_L	60_E	2.396	1.00
385_I	392_T	2.333	1.00
223_D	226_D	2.286	1.00
207_C	224_V	2.273	1.00
7_M	10_I	2.236	1.00
120_E	123_D	2.221	1.00
255_E	279_S	2.213	1.00
299_L	474_I	2.204	1.00
383_S	387_E	2.203	1.00
127_R	189_E	2.178	1.00
18_V	21_D	2.142	1.00
70_I	79_L	2.118	1.00
32_I	183_M	2.079	1.00
347_V	358_L	2.076	1.00
472_A	482_S	2.075	1.00
11_R	18_V	2.065	1.00
260_D	315_T	2.030	1.00
177_K	205_E	2.025	1.00
259_I	262_I	2.017	1.00
234_S	240_E	2.010	1.00
446_E	450_A	1.965	1.00
274_R	478_R	1.958	1.00
113_D	116_R	1.949	1.00
456_L	467_L	1.939	1.00
286_V	472_A	1.934	1.00
47_M	196_I	1.927	1.00
71_N	75_K	1.912	1.00
384_L	413_G	1.905	1.00
228_N	231_E	1.896	1.00
9_N	24_N	1.835	1.00
421_D	452_K	1.829	1.00
8_L	62_R	1.823	1.00
255_E	281_K	1.801	1.00
319_K	332_S	1.798	1.00
280_V	453_A	1.784	1.00
289_A	464_I	1.776	1.00
47_M	83_M	1.743	1.00
259_I	278_L	1.726	1.00
91_V	102_L	1.721	1.00
11_R	22_N	1.719	1.00
425_A	444_L	1.696	1.00
256_V	453_A	1.678	1.00
90_L	138_A	1.674	1.00
382_R	386_T	1.669	1.00
62_R	67_K	1.659	1.00
316_L	321_I	1.655	1.00
357_L	377_M	1.655	1.00
184_K	187_V	1.649	1.00
285_I	444_L	1.647	1.00
287_G	468_S	1.646	1.00
222_L	235_L	1.635	1.00
432_L	440_V	1.633	1.00
300_I	424_I	1.632	1.00
84_V	164_F	1.623	1.00
373_H	376_E	1.595	1.00
185_N	189_E	1.585	1.00
353_G	396_Y	1.582	1.00
382_R	395_E	1.575	1.00
211_T	218_G	1.569	1.00
63_V	161_I	1.558	1.00
399_A	410_A	1.555	1.00
137_K	140_D	1.552	1.00
352_I	392_T	1.545	1.00
4_V	192_S	1.541	1.00
10_I	49_V	1.538	1.00
263_T	275_D	1.533	1.00
13_A	58_R	1.527	1.00
98_E	114_R	1.523	1.00
397_T	401_A	1.519	1.00
97_A	118_G	1.516	1.00
160_D	191_K	1.512	1.00
340_D	343_K	1.511	1.00
93_T	139_A	1.510	1.00
392_T	397_T	1.509	1.00
123_D	127_R	1.508	1.00
119_Q	123_D	1.506	1.00
301_E	344_H	1.501	1.00
256_V	317_N	1.498	1.00
349_D	400_R	1.489	1.00
316_L	422_L	1.488	1.00
484_N	487_E	1.481	1.00
222_L	227_T	1.479	1.00
315_T	320_Q	1.478	1.00
472_A	479_I	1.469	1.00
385_I	390_V	1.461	1.00
7_M	50_L	1.448	1.00
280_V	455_L	1.444	1.00
287_G	464_I	1.438	1.00
116_R	119_Q	1.437	1.00
127_R	185_N	1.433	1.00
204_M	232_L	1.429	1.00
66_E	79_L	1.416	1.00
29_K	192_S	1.414	1.00
387_E	446_E	1.413	1.00
187_V	208_D	1.410	1.00
75_K	78_D	1.410	1.00
324_L	328_K	1.406	1.00
446_E	449_D	1.402	1.00
280_V	422_L	1.400	1.00
302_A	309_T	1.400	1.00
372_L	377_M	1.400	1.00
356_I	390_V	1.393	1.00
255_E	282_A	1.391	1.00
72_S	75_K	1.390	1.00
92_D	146_Q	1.386	1.00
178_E	181_Q	1.381	1.00
100_I	121_V	1.377	1.00
346_L	399_A	1.377	1.00
379_K	383_S	1.377	1.00
53_L	85_H	1.376	1.00
245_T	466_N	1.364	1.00
280_V	286_V	1.364	1.00
180_M	206_I	1.348	1.00
24_N	218_G	1.347	1.00
376_E	379_K	1.336	1.00
227_T	231_E	1.336	1.00
142_S	145_M	1.328	1.00
122_Q	134_P	1.327	1.00
15_P	18_V	1.321	1.00
282_A	421_D	1.314	1.00
11_R	58_R	1.314	1.00
231_E	234_S	1.310	1.00
284_E	470_R	1.310	1.00
96_V	132_I	1.309	1.00
95_T	98_E	1.302	1.00
13_A	57_E	1.300	1.00
264_V	310_D	1.290	1.00
252_P	281_K	1.289	1.00
133_H	136_A	1.286	1.00
273_V	302_A	1.284	1.00
9_N	58_R	1.283	1.00
264_V	302_A	1.283	1.00
419_N	450_A	1.278	1.00
263_T	311_S	1.268	1.00
264_V	273_V	1.259	1.00
366_Y	380_K	1.259	1.00
124_I	156_Y	1.258	1.00
350_F	354_E	1.252	1.00
111_R	371_V	1.250	1.00
185_N	188_K	1.250	1.00
383_S	386_T	1.236	1.00
260_D	279_S	1.236	1.00
51_F	83_M	1.235	1.00
470_R	482_S	1.228	1.00
210_V	224_V	1.226	1.00
278_L	472_A	1.215	1.00
393_P	397_T	1.213	1.00
201_K	229_Q	1.212	1.00
278_L	288_I	1.212	1.00
443_K	446_E	1.207	1.00
27_V	161_I	1.204	1.00
325_T	328_K	1.199	1.00
378_Y	396_Y	1.194	1.00
222_L	226_D	1.189	1.00
204_M	229_Q	1.185	1.00
261_G	277_S	1.182	1.00
398_H	401_A	1.181	1.00
288_I	472_A	1.175	1.00
218_G	221_T	1.150	1.00
282_A	453_A	1.150	1.00
437_I	460_E	1.142	1.00
209_R	223_D	1.135	1.00
126_D	131_Q	1.134	1.00
271_E	274_R	1.132	1.00
15_P	19_A	1.127	1.00
204_M	228_N	1.127	1.00
352_I	410_A	1.125	1.00
458_S	464_I	1.121	1.00
29_K	160_D	1.118	1.00
28_K	31_E	1.117	1.00
183_M	193_I	1.114	1.00
183_M	206_I	1.113	1.00
184_K	188_K	1.103	1.00
327_R	331_E	1.103	1.00
70_I	75_K	1.097	1.00
222_L	231_E	1.095	1.00
264_V	272_T	1.095	1.00
411_I	414_R	1.095	1.00
394_D	397_T	1.093	1.00
297_S	339_Q	1.092	1.00
464_I	468_S	1.092	1.00
212_V	235_L	1.091	1.00
337_I	425_A	1.088	1.00
356_I	381_A	1.088	1.00
380_K	417_D	1.087	1.00
108_K	113_D	1.086	1.00
389_D	439_F	1.082	1.00
286_V	482_S	1.082	1.00
164_F	193_I	1.081	1.00
36_L	200_L	1.076	1.00
97_A	134_P	1.068	1.00
275_D	478_R	1.067	1.00
248_R	449_D	1.065	1.00
181_Q	185_N	1.063	1.00
29_K	64_R	1.063	1.00
26_Q	209_R	1.063	1.00
56_P	69_H	1.061	1.00
419_N	452_K	1.056	1.00
464_I	471_I	1.054	1.00
20_N	49_V	1.053	1.00
211_T	221_T	1.048	1.00
353_G	378_Y	1.047	1.00
33_H	221_T	1.043	1.00
23_I	213_I	1.043	1.00
128_Y	152_L	1.041	1.00
273_V	276_L	1.040	1.00
353_G	377_M	1.039	1.00
338_P	344_H	1.039	1.00
261_G	311_S	1.033	1.00
353_G	395_E	1.031	1.00
4_V	161_I	1.028	1.00
100_I	156_Y	1.025	1.00
351_P	354_E	1.024	1.00
48_N	54_Y	1.023	1.00
75_K	79_L	1.023	1.00
262_I	302_A	1.016	1.00
106_P	117_A	1.013	1.00
278_L	286_V	1.012	1.00
475_F	480_I	1.006	1.00
118_G	122_Q	1.006	1.00
259_I	303_V	1.004	1.00
347_V	350_F	1.002	1.00
159_A	162_L	1.000	1.00
27_V	192_S	0.998	1.00
204_M	224_V	0.991	1.00
5_I	63_V	0.989	1.00
11_R	21_D	0.988	1.00
286_V	455_L	0.988	1.00
68_V	79_L	0.987	1.00
329_I	334_I	0.986	1.00
260_D	277_S	0.986	1.00
254_A	317_N	0.985	1.00
445_I	449_D	0.985	1.00
427_Q	459_F	0.985	1.00
384_L	390_V	0.982	1.00
442_K	446_E	0.982	1.00
323_N	328_K	0.978	1.00
96_V	141_I	0.978	1.00
87_H	342_H	0.973	1.00
123_D	126_D	0.969	1.00
444_L	456_L	0.969	1.00
28_K	209_R	0.968	1.00
356_I	410_A	0.966	1.00
256_V	282_A	0.965	1.00
87_H	430_R	0.965	1.00
288_I	455_L	0.963	1.00
8_L	24_N	0.962	1.00
380_K	383_S	0.959	1.00
115_K	119_Q	0.957	1.00
282_A	317_N	0.949	1.00
106_P	120_E	0.947	1.00
424_I	457_L	0.947	1.00
82_G	154_T	0.943	1.00
134_P	137_K	0.941	1.00
447_Q	452_K	0.940	1.00
288_I	299_L	0.936	1.00
423_L	452_K	0.934	1.00
262_I	309_T	0.934	1.00
55_Q	69_H	0.931	1.00
162_L	193_I	0.931	1.00
342_H	348_L	0.931	1.00
4_V	64_R	0.925	1.00
4_V	63_V	0.921	1.00
335_G	415_E	0.919	1.00
381_A	395_E	0.918	1.00
304_T	424_I	0.917	1.00
337_I	411_I	0.916	1.00
296_Q	426_A	0.914	1.00
393_P	401_A	0.913	1.00
330_T	415_E	0.911	1.00
125_S	152_L	0.911	1.00
323_N	334_I	0.911	1.00
177_K	181_Q	0.910	1.00
158_G	189_E	0.908	1.00
246_E	466_N	0.907	1.00
119_Q	122_Q	0.904	1.00
183_M	195_L	0.904	1.00
203_I	224_V	0.898	1.00
5_I	50_L	0.895	1.00
74_N	78_D	0.895	1.00
333_G	421_D	0.895	1.00
367_S	370_G	0.894	1.00
304_T	415_E	0.893	1.00
352_I	402_L	0.893	1.00
96_V	136_A	0.889	1.00
12_K	57_E	0.889	1.00
209_R	221_T	0.888	1.00
82_G	159_A	0.885	1.00
338_P	411_I	0.884	1.00
323_N	329_I	0.880	1.00
22_N	58_R	0.877	1.00
444_L	467_L	0.876	1.00
335_G	423_L	0.874	1.00
359_Q	415_E	0.874	1.00
97_A	117_A	0.874	1.00
26_Q	221_T	0.873	1.00
77_N	157_R	0.873	1.00
61_I	70_I	0.870	1.00
101_I	120_E	0.866	1.00
259_I	314_I	0.865	1.00
101_I	117_A	0.864	1.00
353_G	381_A	0.862	1.00
334_I	422_L	0.860	1.00
273_V	299_L	0.859	1.00
297_S	426_A	0.854	1.00
63_V	68_V	0.854	1.00
120_E	158_G	0.853	1.00
382_R	385_I	0.852	1.00
438_E	442_K	0.848	1.00
210_V	222_L	0.848	1.00
154_T	162_L	0.846	1.00
33_H	209_R	0.846	1.00
357_L	361_Y	0.845	1.00
253_G	282_A	0.841	1.00
210_V	232_L	0.840	1.00
444_L	454_V	0.839	1.00
424_I	455_L	0.838	1.00
50_L	61_I	0.835	1.00
384_L	417_D	0.835	1.00
348_L	399_A	0.830	1.00
49_V	56_P	0.827	1.00
164_F	183_M	0.826	1.00
468_S	485_P	0.826	1.00
104_K	156_Y	0.822	1.00
264_V	270_I	0.822	1.00
122_Q	135_E	0.818	1.00
51_F	85_H	0.817	1.00
270_I	310_D	0.817	1.00
276_L	299_L	0.812	1.00
49_V	54_Y	0.811	1.00
104_K	157_R	0.808	1.00
130_L	148_R	0.807	1.00
107_K	113_D	0.804	1.00
32_I	184_K	0.799	1.00
375_G	379_K	0.795	1.00
46_L	213_I	0.795	1.00
378_Y	395_E	0.794	1.00
231_E	235_L	0.794	1.00
360_S	417_D	0.793	0.99
32_I	187_V	0.793	0.99
342_H	407_Q	0.792	0.99
22_N	217_K	0.789	0.99
354_E	377_M	0.788	0.99
124_I	152_L	0.787	0.99
335_G	420_P	0.784	0.99
278_L	299_L	0.783	0.99
23_I	218_G	0.782	0.99
129_G	185_N	0.780	0.99
7_M	25_L	0.778	0.99
107_K	110_G	0.777	0.99
479_I	482_S	0.776	0.99
296_Q	339_Q	0.772	0.99
368_A	373_H	0.772	0.99
118_G	134_P	0.770	0.99
8_L	26_Q	0.769	0.99
27_V	194_I	0.767	0.99
106_P	112_I	0.766	0.99
285_I	445_I	0.765	0.99
279_S	482_S	0.763	0.99
82_G	157_R	0.763	0.99
412_I	440_V	0.762	0.99
392_T	395_E	0.761	0.99
276_L	479_I	0.761	0.99
13_A	19_A	0.759	0.99
90_L	146_Q	0.759	0.99
138_A	149_A	0.758	0.99
345_G	411_I	0.757	0.99
264_V	307_R	0.755	0.99
326_P	329_I	0.753	0.99
70_I	76_A	0.752	0.99
356_I	413_G	0.752	0.99
93_T	137_K	0.750	0.99
465_M	471_I	0.747	0.99
89_M	150_E	0.747	0.99
121_V	134_P	0.744	0.99
257_L	280_V	0.740	0.99
346_L	407_Q	0.739	0.99
378_Y	382_R	0.737	0.99
328_K	331_E	0.737	0.99
348_L	400_R	0.735	0.99
108_K	111_R	0.735	0.99
376_E	380_K	0.734	0.99
292_D	459_F	0.733	0.99
28_K	223_D	0.732	0.99
256_V	422_L	0.731	0.99
122_Q	133_H	0.731	0.99
170_V	292_D	0.730	0.99
95_T	137_K	0.730	0.99
365_P	419_N	0.729	0.99
367_S	371_V	0.727	0.99
328_K	332_S	0.726	0.99
351_P	396_Y	0.725	0.99
98_E	105_E	0.724	0.99
15_P	393_P	0.723	0.99
204_M	227_T	0.723	0.99
88_F	143_V	0.723	0.99
392_T	402_L	0.721	0.99
48_N	53_L	0.721	0.99
97_A	106_P	0.721	0.99
162_L	191_K	0.720	0.99
197_T	203_I	0.715	0.99
387_E	443_K	0.714	0.99
127_R	158_G	0.714	0.99
288_I	300_I	0.713	0.99
441_H	466_N	0.709	0.99
316_L	334_I	0.708	0.99
323_N	332_S	0.706	0.99
101_I	121_V	0.704	0.99
7_M	61_I	0.704	0.99
263_T	273_V	0.699	0.99
232_L	236_M	0.698	0.99
234_S	238_G	0.698	0.99
141_I	149_A	0.698	0.99
264_V	309_T	0.694	0.99
247_K	445_I	0.693	0.99
48_N	85_H	0.692	0.99
150_E	153_K	0.691	0.99
125_S	134_P	0.691	0.99
299_L	303_V	0.691	0.99
386_T	389_D	0.688	0.99
122_Q	131_Q	0.688	0.99
34_A	224_V	0.686	0.99
201_K	205_E	0.684	0.99
465_M	485_P	0.681	0.98
288_I	474_I	0.681	0.98
335_G	418_R	0.680	0.98
321_I	332_S	0.679	0.98
258_A	318_G	0.679	0.98
106_P	116_R	0.678	0.98
124_I	127_R	0.675	0.98
309_T	322_Q	0.673	0.98
120_E	124_I	0.672	0.98
74_N	77_N	0.670	0.98
96_V	149_A	0.669	0.98
254_A	281_K	0.668	0.98
248_R	469_D	0.668	0.98
114_R	118_G	0.667	0.98
105_E	117_A	0.663	0.98
264_V	271_E	0.663	0.98
100_I	149_A	0.663	0.98
85_H	89_M	0.663	0.98
25_L	33_H	0.662	0.98
351_P	398_H	0.661	0.98
420_P	452_K	0.659	0.98
257_L	422_L	0.659	0.98
179_L	183_M	0.658	0.98
195_L	206_I	0.656	0.98
182_I	185_N	0.656	0.98
187_V	193_I	0.656	0.98
20_N	213_I	0.656	0.98
35_L	194_I	0.656	0.98
28_K	192_S	0.656	0.98
304_T	336_H	0.653	0.98
97_A	121_V	0.653	0.98
302_A	307_R	0.652	0.98
36_L	203_I	0.651	0.98
90_L	149_A	0.650	0.98
223_D	227_T	0.650	0.98
256_V	280_V	0.650	0.98
412_I	432_L	0.648	0.98
129_G	181_Q	0.647	0.98
352_I	385_I	0.647	0.98
47_M	163_I	0.647	0.98
70_I	81_I	0.647	0.98
447_Q	454_V	0.646	0.98
250_A	253_G	0.645	0.98
262_I	314_I	0.644	0.98
252_P	255_E	0.643	0.98
390_V	413_G	0.643	0.98
420_P	423_L	0.642	0.98
422_L	455_L	0.642	0.98
359_Q	418_R	0.641	0.98
97_A	135_E	0.639	0.98
357_L	380_K	0.639	0.98
232_L	238_G	0.639	0.98
124_I	128_Y	0.638	0.98
184_K	206_I	0.638	0.98
230_D	234_S	0.637	0.98
263_T	274_R	0.637	0.98
447_Q	450_A	0.636	0.98
136_A	145_M	0.634	0.98
247_K	469_D	0.634	0.98
384_L	387_E	0.630	0.97
352_I	399_A	0.630	0.97
379_K	382_R	0.629	0.97
141_I	145_M	0.628	0.97
255_E	260_D	0.628	0.97
304_T	330_T	0.627	0.97
314_I	323_N	0.626	0.97
88_F	150_E	0.625	0.97
68_V	71_N	0.625	0.97
118_G	121_V	0.624	0.97
5_I	161_I	0.623	0.97
259_I	309_T	0.623	0.97
17_I	393_P	0.622	0.97
257_L	261_G	0.621	0.97
316_L	332_S	0.621	0.97
445_I	469_D	0.620	0.97
213_I	218_G	0.619	0.97
300_I	426_A	0.617	0.97
360_S	365_P	0.616	0.97
174_H	177_K	0.616	0.97
119_Q	126_D	0.614	0.97
173_P	177_K	0.613	0.97
7_M	163_I	0.612	0.97
235_L	238_G	0.611	0.97
92_D	139_A	0.610	0.97
107_K	111_R	0.610	0.97
100_I	124_I	0.609	0.97
253_G	281_K	0.608	0.97
237_V	241_V	0.608	0.97
360_S	418_R	0.605	0.97
215_K	391_R	0.605	0.97
13_A	21_D	0.604	0.97
214_R	219_I	0.604	0.97
212_V	232_L	0.603	0.97
380_K	384_L	0.603	0.97
88_F	169_A	0.603	0.97
397_T	400_R	0.601	0.97
300_I	336_H	0.601	0.97
298_E	307_R	0.600	0.97
6_E	65_G	0.599	0.97
96_V	134_P	0.599	0.97
125_S	130_L	0.599	0.97
106_P	113_D	0.596	0.96
456_L	468_S	0.595	0.96
381_A	385_I	0.595	0.96
4_V	29_K	0.595	0.96
200_L	203_I	0.594	0.96
300_I	455_L	0.594	0.96
250_A	449_D	0.590	0.96
448_R	454_V	0.590	0.96
63_V	79_L	0.589	0.96
287_G	458_S	0.589	0.96
172_T	176_I	0.588	0.96
374_K	377_M	0.588	0.96
471_I	485_P	0.587	0.96
143_V	430_R	0.587	0.96
181_Q	188_K	0.586	0.96
384_L	388_Y	0.585	0.96
224_V	227_T	0.583	0.96
304_T	326_P	0.583	0.96
33_H	194_I	0.583	0.96
412_I	416_I	0.583	0.96
473_V	483_V	0.583	0.96
73_P	76_A	0.582	0.96
15_P	21_D	0.582	0.96
391_R	397_T	0.582	0.96
338_P	345_G	0.580	0.96
180_M	187_V	0.580	0.96
337_I	412_I	0.580	0.96
88_F	170_V	0.579	0.96
25_L	35_L	0.579	0.96
27_V	33_H	0.578	0.96
19_A	393_P	0.578	0.96
388_Y	416_I	0.577	0.96
292_D	296_Q	0.577	0.96
136_A	141_I	0.576	0.96
176_I	199_K	0.575	0.96
286_V	453_A	0.575	0.96
131_Q	145_M	0.575	0.96
399_A	411_I	0.575	0.96
388_Y	443_K	0.574	0.96
249_A	252_P	0.573	0.96
143_V	169_A	0.573	0.96
129_G	178_E	0.572	0.96
296_Q	459_F	0.571	0.96
12_K	54_Y	0.571	0.96
263_T	271_E	0.571	0.96
186_L	191_K	0.571	0.96
161_I	192_S	0.570	0.95
412_I	425_A	0.570	0.95
239_R	245_T	0.568	0.95
289_A	461_L	0.568	0.95
25_L	194_I	0.568	0.95
49_V	57_E	0.568	0.95
348_L	414_R	0.568	0.95
262_I	273_V	0.568	0.95
36_L	210_V	0.567	0.95
195_L	203_I	0.567	0.95
168_T	176_I	0.565	0.95
38_E	239_R	0.565	0.95
172_T	175_E	0.565	0.95
230_D	240_E	0.564	0.95
278_L	455_L	0.564	0.95
15_P	397_T	0.563	0.95
38_E	236_M	0.562	0.95
261_G	313_T	0.561	0.95
279_S	282_A	0.560	0.95
187_V	206_I	0.560	0.95
276_L	474_I	0.559	0.95
349_D	398_H	0.557	0.95
352_I	401_A	0.557	0.95
399_A	414_R	0.557	0.95
243_F	246_E	0.556	0.95
169_A	430_R	0.556	0.95
255_E	315_T	0.556	0.95
367_S	373_H	0.555	0.95
388_Y	413_G	0.553	0.95
61_I	68_V	0.553	0.95
181_Q	184_K	0.553	0.95
441_H	445_I	0.551	0.95
285_I	467_L	0.551	0.95
229_Q	232_L	0.551	0.95
181_Q	205_E	0.551	0.95
32_I	208_D	0.551	0.95
281_K	284_E	0.551	0.95
255_E	259_I	0.551	0.95
330_T	359_Q	0.551	0.95
238_G	241_V	0.551	0.95
288_I	479_I	0.550	0.95
32_I	206_I	0.549	0.94
195_L	199_K	0.549	0.94
72_S	76_A	0.549	0.94
128_Y	148_R	0.549	0.94
155_L	186_L	0.549	0.94
301_E	306_L	0.547	0.94
270_I	274_R	0.546	0.94
207_C	210_V	0.546	0.94
473_V	480_I	0.545	0.94
439_F	442_K	0.544	0.94
16_G	19_A	0.543	0.94
35_L	47_M	0.542	0.94
316_L	421_D	0.542	0.94
176_I	206_I	0.542	0.94
352_I	397_T	0.542	0.94
360_S	380_K	0.541	0.94
356_I	385_I	0.540	0.94
31_E	192_S	0.540	0.94
441_H	467_L	0.539	0.94
302_A	308_K	0.539	0.94
200_L	232_L	0.538	0.94
239_R	462_E	0.538	0.94
99_N	138_A	0.538	0.94
47_M	50_L	0.537	0.94
172_T	292_D	0.537	0.94
63_V	81_I	0.537	0.94
7_M	24_N	0.535	0.94
289_A	458_S	0.535	0.94
143_V	146_Q	0.534	0.94
420_P	425_A	0.534	0.94
356_I	384_L	0.533	0.94
220_K	227_T	0.532	0.94
331_E	362_Y	0.531	0.93
304_T	329_I	0.530	0.93
104_K	120_E	0.527	0.93
314_I	321_I	0.527	0.93
365_P	368_A	0.527	0.93
101_I	124_I	0.526	0.93
474_I	479_I	0.526	0.93
144_G	292_D	0.523	0.93
87_H	150_E	0.522	0.93
25_L	192_S	0.522	0.93
324_L	329_I	0.522	0.93
354_E	357_L	0.521	0.93
7_M	49_V	0.519	0.93
236_M	239_R	0.519	0.93
132_I	152_L	0.518	0.93
18_V	22_N	0.517	0.93
482_S	485_P	0.517	0.93
345_G	414_R	0.516	0.92
56_P	67_K	0.515	0.92
163_I	194_I	0.515	0.92
132_I	136_A	0.515	0.92
114_R	117_A	0.514	0.92
20_N	23_I	0.514	0.92
27_V	211_T	0.514	0.92
317_N	320_Q	0.513	0.92
112_I	117_A	0.512	0.92
395_E	398_H	0.512	0.92
262_I	277_S	0.512	0.92
336_H	344_H	0.511	0.92
117_A	120_E	0.509	0.92
173_P	201_K	0.509	0.92
356_I	417_D	0.509	0.92
271_E	310_D	0.509	0.92
439_F	443_K	0.507	0.92
438_E	466_N	0.506	0.92
91_V	94_F	0.505	0.92
282_A	286_V	0.504	0.92
258_A	313_T	0.504	0.92
13_A	16_G	0.503	0.91
33_H	192_S	0.503	0.91
121_V	125_S	0.503	0.91
143_V	170_V	0.501	0.91
392_T	401_A	0.501	0.91
472_A	481_A	0.501	0.91
44_S	48_N	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4q9hA	1	0.951	100	0.403	Contact Map
4finA	2	0.9039	100	0.414	Contact Map
4f4cA	1	0.9333	100	0.429	Contact Map
1yqtA	1	0.9	100	0.45	Contact Map
3ux8A	2	0.8549	100	0.458	Contact Map
3bk7A	1	0.9176	100	0.46	Contact Map
3ozxA	1	0.8902	100	0.461	Contact Map
2iw3A	2	0.8882	100	0.469	Contact Map
3j16B	1	0.9196	100	0.475	Contact Map
2vf7A	2	0.9392	100	0.546	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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