YUGK - BACSU - GREMLIN Contacts

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YUGK - Probable NADH-dependent butanol dehydrogenase 2

UniProt:	O05240	Sequences: MENFTYYNPTKLIFGKGQLEQLRKEFKRYGKNVLLVYGGGSIKRNGLYDQVTGILKEEGAVVHELSGVEPNPRLATVEKGIGLCREHDIDFLLAVGGGSVIDCTKAIAAGVKYDGDAWDIFSKKVTAEDALPFGTVLTLAATGSEMNPDSVITNWETNEKFVWGSNVTHPRFSILDPENTFTVPENQTVYGMVDMMSHVFEQYFHNVENTPLQDRMCFAVLQTVIETAPKLLEDLENYELRETILYAGTIALNGTLQMGYFGDWASHTMEHAVSAVYDIPHAGGLAILFPNWMRYTLDTNVGRFKNLMLNMFDIDTEGKTDKEIALEGIDKLSAFWTSLGAPSRLADYNIGEEKLELIADIAAKEMEHGGFGNFQKLNKDDVLAILRASL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	390 (368)
Sequences:	10276 (7076)
Seq/√Len:	368.9

ECOLI - ADH2 ADHE EUTG YQHD FUCO GLDA YBDH
BACSU - YUGK YUGJ GBSB G1PDH
HALSA - Q9HNB5 Q9HHR2 G1PDH
SULSO - G1PDH Q97VW4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
360_D	379_K	4.040	1.00
356_E	383_L	3.975	1.00
229_P	338_S	3.683	1.00
352_E	387_R	3.338	1.00
82_G	86_E	3.281	1.00
294_R	333_S	3.248	1.00
75_A	155_W	3.191	1.00
80_G	107_I	2.806	1.00
234_D	237_N	2.801	1.00
378_N	381_D	2.701	1.00
227_T	243_T	2.679	1.00
181_F	238_Y	2.648	1.00
230_K	237_N	2.637	1.00
49_D	53_G	2.584	1.00
16_K	178_E	2.501	1.00
67_G	79_K	2.481	1.00
351_G	354_K	2.414	1.00
269_M	386_L	2.402	1.00
21_Q	24_K	2.353	1.00
355_L	383_L	2.352	1.00
219_A	222_Q	2.324	1.00
383_L	387_R	2.322	1.00
344_R	347_D	2.262	1.00
199_V	220_V	2.253	1.00
18_Q	21_Q	2.209	1.00
334_A	338_S	2.171	1.00
17_G	178_E	2.121	1.00
214_D	303_R	2.068	1.00
175_L	245_L	2.061	1.00
195_M	224_V	2.011	1.00
196_M	221_L	2.007	1.00
84_C	131_L	2.007	1.00
379_K	383_L	1.966	1.00
101_I	135_T	1.947	1.00
92_L	104_T	1.940	1.00
63_H	87_H	1.937	1.00
359_A	383_L	1.898	1.00
331_K	334_A	1.859	1.00
41_S	45_N	1.847	1.00
78_E	116_D	1.838	1.00
190_Y	283_G	1.834	1.00
296_T	373_N	1.833	1.00
52_T	56_K	1.821	1.00
294_R	388_A	1.816	1.00
69_E	76_T	1.809	1.00
188_T	241_R	1.807	1.00
358_I	386_L	1.779	1.00
359_A	379_K	1.771	1.00
384_A	388_A	1.770	1.00
287_I	348_Y	1.734	1.00
225_I	312_F	1.730	1.00
49_D	52_T	1.728	1.00
229_P	233_E	1.709	1.00
270_E	284_G	1.706	1.00
356_E	379_K	1.701	1.00
43_K	66_S	1.695	1.00
233_E	338_S	1.682	1.00
308_M	328_G	1.666	1.00
239_E	243_T	1.662	1.00
16_K	238_Y	1.657	1.00
31_K	91_F	1.641	1.00
76_T	79_K	1.634	1.00
337_T	343_S	1.602	1.00
221_L	307_L	1.601	1.00
63_H	83_L	1.600	1.00
94_A	133_F	1.596	1.00
192_M	228_A	1.589	1.00
293_M	332_L	1.581	1.00
79_K	82_G	1.561	1.00
84_C	111_V	1.555	1.00
32_N	61_V	1.554	1.00
185_E	189_V	1.552	1.00
154_N	157_T	1.543	1.00
384_A	387_R	1.541	1.00
40_G	44_R	1.541	1.00
83_L	87_H	1.538	1.00
53_G	57_E	1.530	1.00
11_K	25_E	1.527	1.00
276_V	357_L	1.521	1.00
20_E	50_Q	1.517	1.00
180_T	241_R	1.514	1.00
33_V	38_G	1.490	1.00
16_K	242_E	1.481	1.00
77_V	152_I	1.476	1.00
186_N	283_G	1.474	1.00
63_H	89_I	1.468	1.00
23_R	54_I	1.459	1.00
330_D	334_A	1.458	1.00
25_E	28_R	1.457	1.00
56_K	62_V	1.455	1.00
357_L	361_I	1.454	1.00
354_K	357_L	1.451	1.00
26_F	91_F	1.441	1.00
94_A	104_T	1.437	1.00
52_T	62_V	1.433	1.00
192_M	244_I	1.411	1.00
294_R	326_L	1.408	1.00
74_L	78_E	1.377	1.00
193_V	336_W	1.368	1.00
279_I	284_G	1.365	1.00
269_M	288_L	1.364	1.00
83_L	86_E	1.362	1.00
178_E	238_Y	1.334	1.00
218_F	306_N	1.332	1.00
297_L	326_L	1.332	1.00
227_T	230_K	1.325	1.00
360_D	364_K	1.320	1.00
34_L	91_F	1.320	1.00
50_Q	178_E	1.315	1.00
25_E	172_F	1.314	1.00
180_T	245_L	1.310	1.00
78_E	82_G	1.309	1.00
13_I	25_E	1.307	1.00
108_A	130_A	1.306	1.00
185_E	232_L	1.301	1.00
81_I	110_G	1.296	1.00
33_V	37_Y	1.295	1.00
237_N	240_L	1.289	1.00
116_D	119_D	1.283	1.00
84_C	89_I	1.276	1.00
202_Q	257_Q	1.271	1.00
134_G	172_F	1.266	1.00
381_D	384_A	1.260	1.00
33_V	61_V	1.257	1.00
92_L	108_A	1.255	1.00
188_T	235_L	1.252	1.00
193_V	341_A	1.250	1.00
84_C	107_I	1.245	1.00
77_V	103_C	1.244	1.00
326_L	330_D	1.244	1.00
32_N	90_D	1.241	1.00
69_E	73_R	1.234	1.00
295_Y	381_D	1.232	1.00
380_D	383_L	1.231	1.00
82_G	85_R	1.227	1.00
115_G	119_D	1.225	1.00
230_K	234_D	1.224	1.00
178_E	181_F	1.223	1.00
305_K	324_I	1.223	1.00
291_N	388_A	1.222	1.00
38_G	41_S	1.221	1.00
112_K	129_D	1.215	1.00
115_G	120_I	1.215	1.00
91_F	134_G	1.214	1.00
12_L	249_T	1.210	1.00
306_N	310_N	1.192	1.00
227_T	240_L	1.187	1.00
140_A	188_T	1.182	1.00
31_K	34_L	1.181	1.00
13_I	21_Q	1.176	1.00
218_F	222_Q	1.176	1.00
226_E	243_T	1.176	1.00
357_L	360_D	1.174	1.00
73_R	76_T	1.168	1.00
224_V	244_I	1.164	1.00
265_A	377_L	1.158	1.00
215_R	219_A	1.157	1.00
53_G	56_K	1.150	1.00
18_Q	174_I	1.147	1.00
104_T	133_F	1.142	1.00
218_F	311_M	1.138	1.00
297_L	325_A	1.135	1.00
15_G	18_Q	1.128	1.00
363_A	379_K	1.127	1.00
17_G	20_E	1.121	1.00
188_T	231_L	1.118	1.00
219_A	223_T	1.117	1.00
81_I	85_R	1.108	1.00
19_L	136_V	1.105	1.00
183_V	187_Q	1.102	1.00
307_L	328_G	1.100	1.00
177_P	242_E	1.096	1.00
380_D	384_A	1.085	1.00
298_D	375_Q	1.082	1.00
146_M	249_T	1.073	1.00
269_M	382_V	1.062	1.00
16_K	181_F	1.060	1.00
31_K	90_D	1.059	1.00
299_T	375_Q	1.055	1.00
266_S	289_F	1.052	1.00
149_D	164_G	1.051	1.00
51_V	95_V	1.047	1.00
230_K	240_L	1.047	1.00
185_E	233_E	1.045	1.00
355_L	387_R	1.041	1.00
327_E	330_D	1.039	1.00
27_K	58_E	1.039	1.00
189_V	232_L	1.034	1.00
22_L	51_V	1.033	1.00
19_L	50_Q	1.031	1.00
268_T	370_G	1.023	1.00
74_L	155_W	1.017	1.00
222_Q	310_N	1.006	1.00
193_V	286_A	1.002	1.00
73_R	155_W	1.000	1.00
75_A	156_E	1.000	1.00
276_V	361_I	0.994	1.00
295_Y	375_Q	0.994	1.00
135_T	170_P	0.980	1.00
186_N	190_Y	0.966	1.00
34_L	37_Y	0.965	1.00
11_K	28_R	0.965	1.00
225_I	331_K	0.961	1.00
266_S	285_L	0.961	1.00
356_E	360_D	0.960	1.00
39_G	42_I	0.959	1.00
181_F	236_E	0.958	1.00
24_K	58_E	0.958	1.00
214_D	217_C	0.954	1.00
81_I	107_I	0.951	1.00
305_K	325_A	0.949	1.00
68_V	103_C	0.948	1.00
196_M	224_V	0.945	1.00
224_V	247_A	0.943	1.00
40_G	43_K	0.940	1.00
343_S	347_D	0.938	1.00
230_K	239_E	0.937	1.00
94_A	135_T	0.936	1.00
40_G	66_S	0.932	1.00
220_V	251_A	0.932	1.00
146_M	173_S	0.931	1.00
33_V	39_G	0.927	1.00
202_Q	214_D	0.921	1.00
270_E	274_S	0.918	1.00
203_Y	306_N	0.914	1.00
65_L	80_G	0.914	1.00
323_E	327_E	0.913	1.00
26_F	134_G	0.912	1.00
232_L	339_L	0.907	1.00
222_Q	226_E	0.903	1.00
265_A	292_W	0.903	1.00
71_N	278_D	0.898	1.00
235_L	241_R	0.895	1.00
199_V	251_A	0.892	1.00
42_I	45_N	0.890	1.00
56_K	61_V	0.886	1.00
20_E	54_I	0.884	1.00
223_T	243_T	0.883	1.00
69_E	79_K	0.880	1.00
101_I	137_L	0.879	1.00
132_P	171_R	0.877	1.00
231_L	235_L	0.876	1.00
48_Y	52_T	0.875	1.00
200_F	221_L	0.869	1.00
43_K	49_D	0.869	1.00
17_G	176_D	0.863	1.00
43_K	48_Y	0.861	1.00
197_S	289_F	0.861	1.00
277_Y	354_K	0.860	1.00
19_L	178_E	0.858	1.00
333_S	337_T	0.854	1.00
42_I	48_Y	0.852	1.00
190_Y	280_P	0.852	1.00
310_N	324_I	0.849	1.00
361_I	364_K	0.845	1.00
246_Y	250_I	0.838	1.00
23_R	57_E	0.837	1.00
272_A	386_L	0.837	1.00
314_I	327_E	0.836	1.00
204_F	293_M	0.835	1.00
342_P	347_D	0.834	1.00
38_G	42_I	0.833	1.00
103_C	107_I	0.832	1.00
15_G	21_Q	0.831	1.00
73_R	278_D	0.830	1.00
231_L	240_L	0.828	1.00
19_L	179_N	0.828	1.00
363_A	382_V	0.826	1.00
232_L	340_G	0.824	1.00
50_Q	54_I	0.824	1.00
50_Q	179_N	0.821	1.00
108_A	131_L	0.821	1.00
223_T	247_A	0.820	1.00
94_A	101_I	0.820	1.00
200_F	307_L	0.819	1.00
272_A	361_I	0.809	1.00
148_P	166_N	0.809	1.00
291_N	294_R	0.809	1.00
295_Y	377_L	0.808	1.00
37_Y	40_G	0.805	1.00
22_L	136_V	0.803	1.00
77_V	106_A	0.802	1.00
37_Y	42_I	0.800	1.00
108_A	133_F	0.798	1.00
109_A	168_T	0.794	1.00
135_T	173_S	0.793	1.00
52_T	64_E	0.793	1.00
75_A	79_K	0.790	1.00
185_E	235_L	0.790	1.00
199_V	217_C	0.789	1.00
50_Q	53_G	0.787	1.00
327_E	331_K	0.787	1.00
196_M	200_F	0.784	1.00
209_N	303_R	0.781	1.00
36_V	68_V	0.778	1.00
43_K	52_T	0.778	1.00
189_V	341_A	0.777	1.00
46_G	49_D	0.777	1.00
227_T	244_I	0.776	1.00
273_V	284_G	0.775	1.00
110_G	114_D	0.773	1.00
101_I	144_S	0.773	1.00
158_N	278_D	0.772	1.00
307_L	332_L	0.771	1.00
40_G	67_G	0.768	1.00
206_N	376_K	0.768	1.00
65_L	79_K	0.767	1.00
202_Q	217_C	0.766	1.00
185_E	340_G	0.763	1.00
19_L	176_D	0.761	1.00
301_V	325_A	0.760	1.00
226_E	229_P	0.758	1.00
215_R	222_Q	0.754	1.00
133_F	171_R	0.754	1.00
111_V	131_L	0.751	1.00
334_A	337_T	0.747	1.00
13_I	18_Q	0.746	1.00
140_A	245_L	0.745	1.00
183_V	191_G	0.744	1.00
194_D	281_H	0.743	1.00
230_K	233_E	0.743	1.00
239_E	242_E	0.742	1.00
216_M	250_I	0.740	1.00
203_Y	303_R	0.740	1.00
203_Y	218_F	0.739	1.00
79_K	83_L	0.739	1.00
288_L	385_I	0.736	1.00
359_A	363_A	0.736	1.00
209_N	214_D	0.735	1.00
14_F	242_E	0.734	1.00
113_Y	128_E	0.731	1.00
293_M	304_F	0.731	1.00
267_H	281_H	0.729	1.00
314_I	331_K	0.727	1.00
78_E	81_I	0.724	1.00
54_I	57_E	0.721	1.00
225_I	229_P	0.715	1.00
19_L	51_V	0.714	1.00
192_M	339_L	0.711	0.99
21_Q	25_E	0.711	0.99
227_T	239_E	0.708	0.99
293_M	328_G	0.706	0.99
265_A	382_V	0.705	0.99
290_P	336_W	0.705	0.99
36_V	104_T	0.698	0.99
342_P	348_Y	0.697	0.99
24_K	28_R	0.696	0.99
226_E	230_K	0.696	0.99
35_L	83_L	0.693	0.99
77_V	107_I	0.686	0.99
229_P	232_L	0.686	0.99
209_N	213_Q	0.685	0.99
356_E	359_A	0.685	0.99
34_L	93_L	0.684	0.99
283_G	342_P	0.683	0.99
375_Q	381_D	0.683	0.99
140_A	180_T	0.682	0.99
112_K	131_L	0.681	0.99
180_T	188_T	0.680	0.99
297_L	301_V	0.678	0.99
23_R	58_E	0.675	0.99
355_L	386_L	0.675	0.99
218_F	310_N	0.674	0.99
270_E	285_L	0.667	0.99
377_L	382_V	0.663	0.99
273_V	386_L	0.662	0.99
20_E	57_E	0.662	0.99
335_F	339_L	0.660	0.99
337_T	347_D	0.660	0.99
193_V	339_L	0.659	0.99
26_F	93_L	0.658	0.99
345_L	350_I	0.658	0.99
106_A	152_I	0.654	0.99
19_L	54_I	0.654	0.99
20_E	178_E	0.653	0.99
301_V	304_F	0.653	0.99
49_D	56_K	0.653	0.99
286_A	336_W	0.652	0.99
219_A	250_I	0.652	0.99
293_M	329_I	0.651	0.99
41_S	46_G	0.651	0.99
47_L	95_V	0.649	0.99
41_S	44_R	0.649	0.99
194_D	267_H	0.647	0.99
332_L	336_W	0.647	0.99
311_M	314_I	0.646	0.99
33_V	63_H	0.644	0.99
294_R	329_I	0.644	0.99
106_A	150_S	0.641	0.99
262_G	372_G	0.641	0.99
26_F	60_A	0.641	0.99
211_P	243_T	0.641	0.99
324_I	327_E	0.638	0.99
200_F	289_F	0.637	0.99
137_L	248_G	0.636	0.99
71_N	99_S	0.634	0.99
25_E	29_Y	0.634	0.99
34_L	38_G	0.633	0.99
315_D	324_I	0.633	0.99
231_L	244_I	0.632	0.99
222_Q	311_M	0.631	0.99
247_A	251_A	0.629	0.99
295_Y	378_N	0.628	0.99
38_G	66_S	0.627	0.99
94_A	100_V	0.627	0.99
56_K	59_G	0.627	0.99
227_T	231_L	0.626	0.99
350_I	355_L	0.625	0.99
238_Y	242_E	0.624	0.99
134_G	174_I	0.623	0.99
294_R	297_L	0.623	0.99
352_E	355_L	0.620	0.99
175_L	249_T	0.620	0.99
84_C	92_L	0.620	0.99
365_E	369_G	0.619	0.99
268_T	369_G	0.615	0.99
246_Y	249_T	0.614	0.99
377_L	381_D	0.613	0.98
271_H	365_E	0.613	0.98
13_I	172_F	0.613	0.98
197_S	285_L	0.613	0.98
23_R	27_K	0.611	0.98
150_S	163_W	0.608	0.98
14_F	246_Y	0.606	0.98
42_I	47_L	0.604	0.98
273_V	345_L	0.602	0.98
205_H	372_G	0.598	0.98
113_Y	130_A	0.598	0.98
30_G	90_D	0.596	0.98
229_P	331_K	0.595	0.98
81_I	111_V	0.594	0.98
222_Q	306_N	0.594	0.98
330_D	333_S	0.592	0.98
333_S	343_S	0.591	0.98
304_F	308_M	0.590	0.98
294_R	330_D	0.589	0.98
181_F	241_R	0.588	0.98
280_P	283_G	0.588	0.98
177_P	238_Y	0.587	0.98
197_S	266_S	0.587	0.98
38_G	100_V	0.586	0.98
221_L	225_I	0.586	0.98
206_N	372_G	0.584	0.98
258_M	263_D	0.584	0.98
279_I	348_Y	0.583	0.98
245_L	248_G	0.582	0.98
23_R	26_F	0.582	0.98
47_L	179_N	0.580	0.98
112_K	130_A	0.580	0.98
211_P	226_E	0.580	0.98
306_N	311_M	0.580	0.98
109_A	126_T	0.580	0.98
265_A	268_T	0.579	0.98
16_K	239_E	0.578	0.98
110_G	117_A	0.578	0.98
12_L	173_S	0.577	0.98
37_Y	107_I	0.573	0.98
377_L	385_I	0.573	0.98
78_E	117_A	0.573	0.98
314_I	328_G	0.573	0.98
307_L	312_F	0.571	0.98
24_K	27_K	0.571	0.98
37_Y	100_V	0.570	0.98
285_L	288_L	0.569	0.98
204_F	304_F	0.569	0.98
197_S	264_W	0.568	0.98
26_F	55_L	0.568	0.98
22_L	54_I	0.568	0.98
136_V	174_I	0.563	0.97
29_Y	134_G	0.561	0.97
33_V	91_F	0.560	0.97
305_K	310_N	0.560	0.97
93_L	134_G	0.560	0.97
276_V	358_I	0.559	0.97
33_V	93_L	0.559	0.97
192_M	224_V	0.558	0.97
78_E	118_W	0.558	0.97
200_F	293_M	0.555	0.97
290_P	333_S	0.554	0.97
38_G	43_K	0.552	0.97
274_S	284_G	0.552	0.97
69_E	278_D	0.552	0.97
35_L	38_G	0.552	0.97
33_V	87_H	0.549	0.97
55_L	62_V	0.548	0.97
287_I	345_L	0.547	0.97
137_L	175_L	0.544	0.97
283_G	341_A	0.544	0.97
301_V	305_K	0.543	0.97
27_K	60_A	0.543	0.97
308_M	314_I	0.542	0.97
149_D	162_V	0.542	0.97
359_A	382_V	0.539	0.97
200_F	328_G	0.538	0.97
120_I	124_K	0.537	0.97
255_T	258_M	0.537	0.97
310_N	313_D	0.535	0.96
225_I	335_F	0.534	0.96
160_K	281_H	0.534	0.96
122_S	125_V	0.533	0.96
43_K	46_G	0.533	0.96
47_L	50_Q	0.532	0.96
59_G	62_V	0.532	0.96
32_N	88_D	0.531	0.96
114_D	120_I	0.530	0.96
45_N	48_Y	0.527	0.96
162_V	369_G	0.526	0.96
203_Y	214_D	0.525	0.96
106_A	163_W	0.525	0.96
244_I	248_G	0.524	0.96
269_M	362_A	0.522	0.96
130_A	171_R	0.521	0.96
325_A	328_G	0.520	0.96
210_T	213_Q	0.519	0.96
295_Y	385_I	0.518	0.96
303_R	306_N	0.518	0.96
51_V	54_I	0.518	0.96
198_H	251_A	0.517	0.96
34_L	60_A	0.517	0.96
117_A	120_I	0.516	0.96
304_F	328_G	0.516	0.96
146_M	256_L	0.515	0.96
212_L	215_R	0.514	0.96
336_W	341_A	0.514	0.96
198_H	281_H	0.514	0.96
35_L	89_I	0.514	0.96
182_T	236_E	0.513	0.96
361_I	365_E	0.513	0.96
148_P	259_G	0.513	0.96
48_Y	95_V	0.511	0.95
273_V	358_I	0.510	0.95
43_K	64_E	0.510	0.95
352_E	356_E	0.509	0.95
315_D	327_E	0.509	0.95
221_L	311_M	0.508	0.95
74_L	154_N	0.506	0.95
223_T	227_T	0.506	0.95
242_E	246_Y	0.505	0.95
35_L	48_Y	0.505	0.95
71_N	274_S	0.504	0.95
61_V	87_H	0.503	0.95
185_E	236_E	0.503	0.95
208_E	262_G	0.503	0.95
177_P	245_L	0.502	0.95
76_T	103_C	0.502	0.95
223_T	250_I	0.502	0.95
297_L	304_F	0.501	0.95
41_S	100_V	0.501	0.95
221_L	224_V	0.501	0.95
248_G	251_A	0.501	0.95
118_W	154_N	0.500	0.95
91_F	132_P	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ox4A	2	0.9795	100	0.089	Contact Map
3bfjA	5	0.9769	100	0.09	Contact Map
1vljA	2	0.9769	100	0.113	Contact Map
1rrmA	2	0.9744	100	0.113	Contact Map
4fr2A	2	0.9769	100	0.118	Contact Map
4qgsA	2	0.9538	100	0.144	Contact Map
3zdrA	2	0.9641	100	0.151	Contact Map
1o2dA	1	0.9179	100	0.173	Contact Map
3w5sA	2	0.8795	100	0.203	Contact Map
3iv7A	2	0.8769	100	0.204	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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