MRPD - BACSU - GREMLIN Contacts

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MRPD - Na(+)/H(+) antiporter subunit D

UniProt:	O05229	Sequences: MNNFVILPILIPLLSAILLIFMTKNLMLMRIFSTAASAIGIVISGILVQTVFTKGIQTLSLGGWKAPYGIVLAADQFASLLVLTTAIIGLLVGLYSFRSVGEKRERSFYYSGVQFLLAGVSGAFLTGDLFNMYVFFELLLIASYMLIVLGGTKIQLRESLKYIVFNIVSSALFVIGVGFLYAVTGTLNMADLSVKISESGQTGLITVIGVLLLLVFGMKGGIFPLYFWLPGSYYAPPAAISALFGALLTKVGLYAITRVFTLIFIHDTAFTHQLMIWLAALTVIFGVIGSLAYSNVMKIVIYNIITAVGVILFGVAVHTPASIQGAIYYLIHDMLIKGALFMLAGTLIALTGTASLHKMGGLIKRYPVLGWMFFISAISLAGIPPLSGFVGKFKIAEGGFAEGEFTISMLILLSSLLVLYSVLRIFIHAFWGEEKETPKPNHRTAKGLLYPAAIFLLLSLLFGLGTEWVSPYVDQAAETLLNPEKYIEAVLKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	493 (457)
Sequences:	20311 (12551)
Seq/√Len:	587.1

ECOLI - HYFB NUOL HYCC NUOM HYFF HYFD NUON
BACSU - MRPD MRPA NDHF
HALSA - Q9HRL3 Q9HRL2 Q9HRT0 Q9HRS9 Q9HRL1 Q9HRS8
SULSO - Q980G8 Q97ZA6 Q97ZA9 Q980G9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
75_D	258_R	4.708	1.00
339_A	376_S	4.619	1.00
122_G	135_F	4.392	1.00
188_N	191_D	4.043	1.00
82_V	125_L	3.795	1.00
148_V	159_S	3.572	1.00
332_H	387_S	3.244	1.00
161_K	231_G	3.238	1.00
295_N	354_A	3.171	1.00
89_G	117_L	3.103	1.00
186_T	191_D	3.001	1.00
329_Y	391_G	2.949	1.00
283_V	414_S	2.918	1.00
15_S	36_A	2.842	1.00
294_S	357_H	2.810	1.00
279_A	316_A	2.730	1.00
374_F	426_F	2.662	1.00
300_V	344_A	2.646	1.00
119_G	138_L	2.629	1.00
176_G	211_L	2.612	1.00
353_T	358_K	2.581	1.00
85_T	124_F	2.578	1.00
82_V	121_S	2.546	1.00
13_L	118_A	2.526	1.00
222_I	312_L	2.468	1.00
355_S	358_K	2.442	1.00
38_A	90_L	2.302	1.00
96_S	109_Y	2.285	1.00
377_A	422_V	2.264	1.00
299_I	356_L	2.226	1.00
73_A	127_G	2.220	1.00
233_Y	241_S	2.209	1.00
86_A	121_S	2.195	1.00
291_L	420_Y	2.191	1.00
233_Y	249_T	2.071	1.00
313_F	411_I	2.005	1.00
314_G	395_I	1.998	1.00
273_Q	277_W	1.956	1.00
303_N	421_S	1.939	1.00
217_G	222_I	1.929	1.00
249_T	304_I	1.904	1.00
294_S	355_S	1.891	1.00
284_I	414_S	1.858	1.00
41_I	87_I	1.837	1.00
75_D	78_A	1.813	1.00
366_Y	369_L	1.805	1.00
191_D	194_V	1.802	1.00
317_V	322_S	1.798	1.00
424_R	428_H	1.781	1.00
287_V	306_T	1.758	1.00
296_V	425_I	1.748	1.00
129_L	192_L	1.745	1.00
276_I	316_A	1.745	1.00
465_G	468_W	1.734	1.00
446_K	450_Y	1.731	1.00
105_E	108_F	1.729	1.00
396_A	411_I	1.727	1.00
221_G	229_L	1.714	1.00
179_F	208_I	1.709	1.00
328_Y	391_G	1.705	1.00
129_L	259_V	1.680	1.00
38_A	42_V	1.677	1.00
132_M	255_A	1.674	1.00
25_N	28_L	1.665	1.00
325_G	398_G	1.650	1.00
213_L	217_G	1.650	1.00
293_Y	298_K	1.646	1.00
127_G	190_A	1.642	1.00
223_F	281_L	1.617	1.00
257_T	315_V	1.617	1.00
363_I	370_G	1.600	1.00
270_F	273_Q	1.599	1.00
78_A	254_Y	1.585	1.00
84_T	334_M	1.582	1.00
335_L	458_L	1.579	1.00
48_V	52_F	1.571	1.00
399_G	408_S	1.564	1.00
80_L	331_I	1.544	1.00
183_V	208_I	1.532	1.00
126_T	131_N	1.532	1.00
280_A	410_L	1.525	1.00
73_A	76_Q	1.519	1.00
44_S	86_A	1.519	1.00
27_M	30_R	1.517	1.00
128_D	188_N	1.492	1.00
191_D	195_K	1.492	1.00
457_L	461_L	1.490	1.00
275_M	316_A	1.472	1.00
397_E	401_A	1.470	1.00
375_I	456_L	1.469	1.00
203_G	207_V	1.446	1.00
369_L	443_R	1.445	1.00
9_I	118_A	1.432	1.00
28_L	31_I	1.427	1.00
287_V	414_S	1.415	1.00
93_G	110_Y	1.414	1.00
42_V	46_I	1.414	1.00
276_I	407_I	1.410	1.00
23_T	107_S	1.409	1.00
26_L	30_R	1.408	1.00
112_G	145_M	1.407	1.00
315_V	326_A	1.406	1.00
373_F	377_A	1.406	1.00
63_G	69_G	1.394	1.00
181_Y	187_L	1.390	1.00
454_I	458_L	1.388	1.00
213_L	275_M	1.383	1.00
128_D	187_L	1.382	1.00
37_S	41_I	1.378	1.00
311_I	326_A	1.371	1.00
58_T	61_L	1.369	1.00
272_H	276_I	1.368	1.00
222_I	278_L	1.367	1.00
176_G	215_V	1.355	1.00
36_A	40_G	1.345	1.00
173_F	215_V	1.340	1.00
216_F	255_A	1.334	1.00
256_I	312_L	1.326	1.00
40_G	44_S	1.326	1.00
340_L	376_S	1.323	1.00
93_G	113_V	1.319	1.00
95_Y	342_M	1.317	1.00
158_E	235_A	1.316	1.00
370_G	431_W	1.316	1.00
176_G	212_L	1.315	1.00
451_P	454_I	1.311	1.00
257_T	326_A	1.310	1.00
250_K	254_Y	1.304	1.00
446_K	449_L	1.297	1.00
370_G	426_F	1.294	1.00
314_G	322_S	1.291	1.00
176_G	208_I	1.281	1.00
336_I	379_S	1.278	1.00
373_F	425_I	1.269	1.00
74_A	125_L	1.267	1.00
445_A	448_L	1.262	1.00
178_G	182_A	1.259	1.00
317_V	399_G	1.258	1.00
123_A	251_V	1.258	1.00
98_R	101_G	1.257	1.00
71_V	127_G	1.257	1.00
165_F	227_F	1.251	1.00
80_L	327_I	1.246	1.00
46_I	50_T	1.242	1.00
314_G	326_A	1.240	1.00
154_I	234_Y	1.239	1.00
20_I	23_T	1.230	1.00
313_F	399_G	1.228	1.00
177_V	212_L	1.225	1.00
231_G	298_K	1.219	1.00
453_A	457_L	1.218	1.00
418_V	421_S	1.212	1.00
37_S	40_G	1.211	1.00
45_G	49_Q	1.210	1.00
377_A	426_F	1.207	1.00
16_A	115_F	1.206	1.00
130_F	187_L	1.200	1.00
467_E	471_P	1.197	1.00
332_H	391_G	1.194	1.00
285_F	289_G	1.194	1.00
31_I	35_A	1.193	1.00
9_I	12_P	1.190	1.00
116_L	120_V	1.185	1.00
279_A	309_G	1.184	1.00
88_I	334_M	1.182	1.00
376_S	456_L	1.181	1.00
133_Y	174_V	1.180	1.00
27_M	31_I	1.175	1.00
41_I	86_A	1.174	1.00
81_L	330_L	1.173	1.00
132_M	189_M	1.173	1.00
322_S	398_G	1.166	1.00
127_G	188_N	1.166	1.00
356_L	429_A	1.162	1.00
179_F	204_L	1.157	1.00
88_I	338_G	1.153	1.00
35_A	39_I	1.153	1.00
16_A	19_L	1.145	1.00
40_G	47_L	1.141	1.00
277_W	281_L	1.137	1.00
16_A	20_I	1.136	1.00
249_T	254_Y	1.123	1.00
343_L	373_F	1.121	1.00
348_I	354_A	1.120	1.00
380_L	422_V	1.116	1.00
157_R	161_K	1.116	1.00
468_W	471_P	1.114	1.00
246_A	250_K	1.112	1.00
129_L	177_V	1.112	1.00
286_G	309_G	1.111	1.00
146_L	240_I	1.105	1.00
60_S	63_G	1.105	1.00
406_T	409_M	1.105	1.00
306_T	418_V	1.104	1.00
249_T	253_L	1.100	1.00
372_M	456_L	1.097	1.00
245_G	249_T	1.093	1.00
325_G	394_K	1.089	1.00
173_F	177_V	1.088	1.00
183_V	204_L	1.085	1.00
91_L	454_I	1.083	1.00
374_F	430_F	1.082	1.00
217_G	278_L	1.080	1.00
169_S	218_M	1.077	1.00
86_A	90_L	1.073	1.00
90_L	94_L	1.070	1.00
49_Q	52_F	1.069	1.00
368_V	371_W	1.068	1.00
333_D	337_K	1.065	1.00
394_K	397_E	1.064	1.00
190_A	194_V	1.061	1.00
152_T	155_Q	1.060	1.00
33_S	37_S	1.056	1.00
350_L	366_Y	1.050	1.00
41_I	45_G	1.050	1.00
409_M	413_L	1.046	1.00
95_Y	345_G	1.044	1.00
218_M	225_L	1.040	1.00
29_M	33_S	1.038	1.00
400_F	408_S	1.036	1.00
458_L	462_F	1.036	1.00
87_I	91_L	1.033	1.00
77_F	257_T	1.030	1.00
78_A	258_R	1.026	1.00
19_L	23_T	1.025	1.00
48_V	83_L	1.023	1.00
61_L	69_G	1.021	1.00
223_F	285_F	1.018	1.00
43_I	47_L	1.014	1.00
208_I	212_L	1.012	1.00
74_A	79_S	1.011	1.00
206_T	271_T	1.008	1.00
343_L	452_A	1.001	1.00
184_T	192_L	0.998	1.00
346_T	452_A	0.994	1.00
44_S	47_L	0.988	1.00
456_L	460_L	0.985	1.00
368_V	453_A	0.984	1.00
26_L	29_M	0.983	1.00
115_F	142_A	0.980	1.00
230_P	302_Y	0.980	1.00
360_G	435_K	0.976	1.00
279_A	313_F	0.976	1.00
85_T	117_L	0.974	1.00
296_V	344_A	0.973	1.00
114_Q	118_A	0.971	1.00
378_I	383_I	0.966	1.00
98_R	445_A	0.964	1.00
373_F	430_F	0.963	1.00
387_S	462_F	0.963	1.00
186_T	189_M	0.960	1.00
37_S	93_G	0.959	1.00
372_M	452_A	0.958	1.00
33_S	110_Y	0.955	1.00
229_L	233_Y	0.955	1.00
8_P	43_I	0.952	1.00
203_G	206_T	0.952	1.00
213_L	256_I	0.951	1.00
368_V	372_M	0.951	1.00
63_G	66_A	0.950	1.00
189_M	193_S	0.949	1.00
172_L	211_L	0.949	1.00
143_S	248_L	0.949	1.00
256_I	315_V	0.948	1.00
339_A	455_F	0.947	1.00
447_G	451_P	0.943	1.00
369_L	444_T	0.942	1.00
77_F	327_I	0.942	1.00
287_V	417_L	0.941	1.00
328_Y	332_H	0.939	1.00
233_Y	304_I	0.938	1.00
29_M	32_F	0.937	1.00
172_L	214_L	0.934	1.00
119_G	142_A	0.933	1.00
181_Y	184_T	0.932	1.00
33_S	36_A	0.932	1.00
238_A	297_M	0.932	1.00
88_I	246_A	0.928	1.00
241_S	244_F	0.928	1.00
414_S	417_L	0.925	1.00
98_R	447_G	0.922	1.00
30_R	33_S	0.920	1.00
206_T	270_F	0.920	1.00
8_P	12_P	0.918	1.00
304_I	333_D	0.917	1.00
370_G	430_F	0.915	1.00
180_L	192_L	0.914	1.00
311_I	330_L	0.913	1.00
314_G	325_G	0.910	1.00
307_A	329_Y	0.910	1.00
290_S	421_S	0.908	1.00
283_V	313_F	0.906	1.00
372_M	453_A	0.905	1.00
180_L	208_I	0.904	1.00
280_A	407_I	0.899	1.00
7_L	11_I	0.896	1.00
46_I	49_Q	0.892	1.00
273_Q	276_I	0.890	1.00
360_G	428_H	0.890	1.00
120_V	139_L	0.889	1.00
346_T	369_L	0.888	1.00
210_V	214_L	0.886	1.00
287_V	421_S	0.885	1.00
207_V	211_L	0.885	1.00
426_F	431_W	0.885	1.00
78_A	82_V	0.884	1.00
11_I	15_S	0.883	1.00
295_N	355_S	0.883	1.00
281_L	285_F	0.880	1.00
206_T	210_V	0.879	1.00
349_A	442_H	0.877	1.00
351_T	359_M	0.876	1.00
283_V	309_G	0.876	1.00
47_L	51_V	0.875	1.00
276_I	279_A	0.875	1.00
288_I	417_L	0.873	1.00
347_L	362_L	0.871	1.00
120_V	248_L	0.871	1.00
393_F	397_E	0.870	1.00
187_L	191_D	0.870	1.00
236_P	239_A	0.869	1.00
119_G	135_F	0.869	1.00
16_A	111_S	0.869	1.00
133_Y	177_V	0.868	1.00
72_L	125_L	0.865	1.00
199_S	202_T	0.864	1.00
201_Q	205_I	0.862	1.00
247_L	250_K	0.862	1.00
350_L	448_L	0.859	1.00
220_G	253_L	0.859	1.00
20_I	111_S	0.856	1.00
121_S	125_L	0.855	1.00
89_G	113_V	0.853	1.00
147_I	232_S	0.853	1.00
154_I	235_A	0.850	1.00
71_V	188_N	0.849	1.00
156_L	159_S	0.848	1.00
450_Y	454_I	0.848	1.00
276_I	280_A	0.843	1.00
253_L	311_I	0.835	1.00
296_V	359_M	0.833	1.00
307_A	418_V	0.833	1.00
202_T	206_T	0.833	1.00
299_I	425_I	0.830	1.00
201_Q	204_L	0.827	1.00
133_Y	137_E	0.827	1.00
15_S	19_L	0.827	1.00
85_T	120_V	0.824	1.00
68_Y	130_F	0.824	1.00
116_L	143_S	0.822	1.00
310_V	395_I	0.819	1.00
92_V	342_M	0.819	1.00
253_L	312_L	0.816	1.00
371_W	430_F	0.815	1.00
233_Y	236_P	0.815	1.00
280_A	313_F	0.814	1.00
307_A	421_S	0.812	1.00
31_I	34_T	0.812	1.00
17_I	20_I	0.812	1.00
16_A	118_A	0.812	1.00
24_K	27_M	0.811	1.00
186_T	192_L	0.811	1.00
39_I	43_I	0.806	1.00
10_L	14_L	0.805	1.00
9_I	125_L	0.804	1.00
422_V	425_I	0.804	1.00
346_T	444_T	0.804	1.00
14_L	18_L	0.803	1.00
237_P	240_I	0.803	1.00
209_G	271_T	0.802	1.00
336_I	388_G	0.800	1.00
51_V	79_S	0.800	1.00
461_L	465_G	0.795	1.00
286_G	306_T	0.794	1.00
179_F	183_V	0.794	1.00
84_T	331_I	0.792	1.00
356_L	428_H	0.790	1.00
371_W	375_I	0.789	1.00
9_I	72_L	0.785	1.00
107_S	111_S	0.785	1.00
253_L	330_L	0.784	1.00
250_K	253_L	0.782	1.00
300_V	340_L	0.782	1.00
387_S	459_S	0.779	1.00
153_K	234_Y	0.777	1.00
242_A	342_M	0.772	1.00
423_L	427_I	0.772	1.00
167_I	170_S	0.771	1.00
370_G	374_F	0.771	1.00
254_Y	258_R	0.770	1.00
381_A	419_L	0.768	1.00
139_L	248_L	0.767	1.00
144_Y	159_S	0.767	1.00
269_A	272_H	0.767	1.00
287_V	303_N	0.762	1.00
279_A	312_L	0.761	1.00
276_I	313_F	0.760	1.00
365_R	434_E	0.760	1.00
50_T	54_K	0.759	1.00
32_F	36_A	0.758	1.00
386_L	390_V	0.754	1.00
364_K	367_P	0.752	1.00
396_A	408_S	0.752	1.00
366_Y	443_R	0.752	1.00
441_N	444_T	0.752	1.00
444_T	449_L	0.750	1.00
83_L	86_A	0.748	1.00
435_K	438_P	0.748	1.00
116_L	243_L	0.745	1.00
33_S	40_G	0.745	1.00
257_T	323_I	0.743	1.00
353_T	359_M	0.742	1.00
136_F	173_F	0.742	1.00
329_Y	336_I	0.740	1.00
154_I	157_R	0.740	1.00
385_P	464_L	0.739	1.00
303_N	333_D	0.739	1.00
456_L	459_S	0.739	1.00
45_G	83_L	0.738	1.00
310_V	414_S	0.738	1.00
336_I	459_S	0.737	1.00
416_L	420_Y	0.736	1.00
342_M	451_P	0.735	1.00
377_A	425_I	0.735	1.00
79_S	83_L	0.733	1.00
97_F	447_G	0.731	1.00
449_L	453_A	0.730	1.00
174_V	178_G	0.730	1.00
91_L	451_P	0.727	1.00
28_L	32_F	0.726	1.00
106_R	110_Y	0.725	1.00
293_Y	302_Y	0.723	1.00
360_G	432_G	0.719	1.00
419_L	423_L	0.718	1.00
205_I	208_I	0.717	1.00
160_L	164_V	0.716	1.00
47_L	50_T	0.716	1.00
365_R	441_N	0.716	1.00
320_P	324_Q	0.715	1.00
372_M	376_S	0.712	1.00
443_R	449_L	0.710	1.00
144_Y	166_N	0.709	1.00
202_T	205_I	0.709	1.00
96_S	99_S	0.708	1.00
379_S	386_L	0.707	1.00
91_L	455_F	0.707	1.00
382_G	392_K	0.706	1.00
236_P	240_I	0.705	1.00
49_Q	53_T	0.705	1.00
147_I	244_F	0.705	1.00
317_V	402_E	0.704	1.00
286_G	289_G	0.703	1.00
284_I	288_I	0.700	1.00
368_V	449_L	0.698	1.00
12_P	15_S	0.696	1.00
30_R	34_T	0.692	1.00
15_S	20_I	0.691	1.00
462_F	469_V	0.690	1.00
234_Y	295_N	0.690	1.00
253_L	308_V	0.688	1.00
83_L	87_I	0.688	1.00
371_W	374_F	0.687	1.00
279_A	283_V	0.687	1.00
274_L	277_W	0.684	1.00
436_E	439_K	0.684	1.00
25_N	29_M	0.683	1.00
59_L	71_V	0.682	1.00
180_L	212_L	0.682	1.00
268_T	272_H	0.681	1.00
62_G	65_K	0.679	1.00
73_A	190_A	0.679	1.00
280_A	284_I	0.675	1.00
375_I	460_L	0.673	1.00
307_A	337_K	0.671	1.00
245_G	333_D	0.671	1.00
322_S	326_A	0.670	1.00
147_I	236_P	0.670	1.00
136_F	251_V	0.669	1.00
259_V	263_I	0.669	1.00
128_D	131_N	0.668	1.00
85_T	121_S	0.667	1.00
113_V	243_L	0.667	1.00
44_S	48_V	0.665	1.00
234_Y	298_K	0.664	1.00
71_V	128_D	0.661	1.00
396_A	415_S	0.660	1.00
41_I	48_V	0.659	1.00
26_L	31_I	0.656	1.00
86_A	117_L	0.656	1.00
233_Y	244_F	0.653	1.00
34_T	94_L	0.653	1.00
51_V	55_G	0.653	1.00
37_S	47_L	0.649	1.00
384_P	389_F	0.647	1.00
11_I	36_A	0.647	1.00
392_K	415_S	0.646	1.00
303_N	337_K	0.645	1.00
15_S	40_G	0.645	1.00
461_L	468_W	0.645	1.00
289_G	302_Y	0.642	1.00
296_V	429_A	0.641	1.00
209_G	213_L	0.641	1.00
343_L	376_S	0.636	1.00
450_Y	453_A	0.635	1.00
287_V	418_V	0.633	1.00
137_E	219_K	0.632	1.00
15_S	114_Q	0.631	1.00
245_G	250_K	0.628	1.00
200_G	203_G	0.628	1.00
410_L	414_S	0.628	1.00
233_Y	301_I	0.627	1.00
150_G	153_K	0.627	1.00
284_I	410_L	0.627	1.00
227_F	230_P	0.626	1.00
77_F	81_L	0.625	1.00
91_L	338_G	0.625	1.00
61_L	65_K	0.624	1.00
34_T	38_A	0.624	1.00
87_I	458_L	0.624	1.00
132_M	173_F	0.623	1.00
92_V	113_V	0.623	1.00
34_T	97_F	0.623	1.00
238_A	345_G	0.622	1.00
9_I	16_A	0.622	1.00
394_K	470_S	0.621	1.00
293_Y	299_I	0.621	1.00
52_F	55_G	0.621	1.00
11_I	39_I	0.620	1.00
192_L	195_K	0.620	1.00
169_S	215_V	0.620	1.00
343_L	372_M	0.619	1.00
230_P	305_I	0.619	1.00
11_I	43_I	0.619	1.00
246_A	338_G	0.619	1.00
53_T	56_I	0.613	1.00
372_M	449_L	0.611	1.00
109_Y	239_A	0.610	1.00
36_A	114_Q	0.609	1.00
124_F	254_Y	0.606	1.00
26_L	34_T	0.605	1.00
51_V	54_K	0.605	1.00
74_A	78_A	0.605	1.00
336_I	380_L	0.604	1.00
129_L	180_L	0.604	1.00
127_G	131_N	0.603	1.00
116_L	248_L	0.603	1.00
303_N	307_A	0.601	1.00
81_L	85_T	0.601	1.00
213_L	271_T	0.599	1.00
362_L	366_Y	0.598	1.00
37_S	43_I	0.594	1.00
207_V	210_V	0.594	1.00
329_Y	332_H	0.593	1.00
43_I	46_I	0.592	1.00
115_F	119_G	0.592	1.00
15_S	32_F	0.591	1.00
229_L	249_T	0.591	1.00
34_T	37_S	0.589	1.00
92_V	239_A	0.589	1.00
363_I	430_F	0.588	1.00
382_G	388_G	0.586	1.00
40_G	86_A	0.586	1.00
204_L	208_I	0.585	1.00
356_L	359_M	0.585	1.00
335_L	387_S	0.585	1.00
289_G	293_Y	0.585	1.00
304_I	308_V	0.584	1.00
390_V	464_L	0.584	1.00
246_A	249_T	0.584	1.00
63_G	67_P	0.583	1.00
462_F	466_T	0.582	1.00
175_I	179_F	0.582	1.00
339_A	452_A	0.581	1.00
193_S	261_T	0.580	1.00
237_P	241_S	0.580	1.00
412_L	415_S	0.580	1.00
294_S	303_N	0.577	1.00
346_T	350_L	0.577	1.00
31_I	38_A	0.576	1.00
229_L	232_S	0.576	1.00
88_I	243_L	0.575	1.00
8_P	20_I	0.575	1.00
382_G	386_L	0.573	1.00
179_F	207_V	0.573	1.00
139_L	251_V	0.572	1.00
426_F	430_F	0.572	1.00
129_L	189_M	0.570	1.00
108_F	112_G	0.570	1.00
211_L	215_V	0.569	1.00
204_L	207_V	0.567	1.00
270_F	274_L	0.567	1.00
25_N	30_R	0.566	1.00
379_S	388_G	0.566	1.00
89_G	243_L	0.565	1.00
283_V	310_V	0.565	1.00
58_T	62_G	0.564	1.00
40_G	43_I	0.564	1.00
346_T	448_L	0.563	1.00
307_A	380_L	0.562	0.99
374_F	431_W	0.561	0.99
50_T	53_T	0.558	0.99
35_A	38_A	0.556	0.99
126_T	135_F	0.555	0.99
199_S	203_G	0.555	0.99
112_G	142_A	0.555	0.99
12_P	16_A	0.553	0.99
143_S	146_L	0.553	0.99
41_I	90_L	0.552	0.99
331_I	469_V	0.552	0.99
390_V	394_K	0.551	0.99
420_Y	424_R	0.551	0.99
28_L	36_A	0.547	0.99
343_L	369_L	0.547	0.99
15_S	23_T	0.546	0.99
256_I	263_I	0.546	0.99
8_P	13_L	0.546	0.99
374_F	378_I	0.545	0.99
401_A	404_E	0.544	0.99
236_P	241_S	0.543	0.99
127_G	258_R	0.543	0.99
277_W	280_A	0.542	0.99
233_Y	246_A	0.542	0.99
34_T	41_I	0.542	0.99
94_L	450_Y	0.542	0.99
120_V	247_L	0.542	0.99
223_F	286_G	0.540	0.99
460_L	464_L	0.538	0.99
38_A	41_I	0.537	0.99
363_I	374_F	0.537	0.99
234_Y	245_G	0.537	0.99
81_L	124_F	0.537	0.99
289_G	292_A	0.537	0.99
181_Y	185_G	0.535	0.99
109_Y	149_L	0.535	0.99
422_V	426_F	0.534	0.99
143_S	147_I	0.534	0.99
12_P	118_A	0.533	0.99
26_L	33_S	0.532	0.99
33_S	114_Q	0.532	0.99
157_R	231_G	0.532	0.99
467_E	470_S	0.531	0.99
333_D	341_F	0.531	0.99
8_P	47_L	0.529	0.99
84_T	330_L	0.528	0.99
85_T	89_G	0.528	0.99
28_L	34_T	0.527	0.99
37_S	44_S	0.527	0.99
249_T	308_V	0.527	0.99
446_K	451_P	0.527	0.99
248_L	251_V	0.525	0.99
45_G	87_I	0.523	0.99
444_T	448_L	0.523	0.99
117_L	121_S	0.522	0.99
356_L	425_I	0.521	0.99
133_Y	170_S	0.520	0.99
44_S	82_V	0.519	0.99
40_G	51_V	0.518	0.99
11_I	23_T	0.518	0.99
367_P	370_G	0.518	0.99
233_Y	297_M	0.518	0.99
378_I	423_L	0.517	0.99
165_F	218_M	0.517	0.99
396_A	412_L	0.516	0.99
140_L	166_N	0.516	0.99
442_H	446_K	0.515	0.99
381_A	422_V	0.515	0.99
322_S	325_G	0.515	0.99
189_M	263_I	0.514	0.99
349_A	448_L	0.514	0.99
288_I	292_A	0.513	0.99
7_L	14_L	0.511	0.99
296_V	347_L	0.509	0.99
40_G	121_S	0.508	0.99
286_G	305_I	0.507	0.99
374_F	377_A	0.504	0.99
33_S	93_G	0.504	0.99
112_G	115_F	0.504	0.99
349_A	445_A	0.503	0.99
213_L	278_L	0.503	0.99
152_T	235_A	0.502	0.99
88_I	92_V	0.502	0.99
398_G	402_E	0.502	0.99
184_T	188_N	0.501	0.99
140_L	143_S	0.501	0.99
328_Y	394_K	0.501	0.99
220_G	256_I	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3rkoM	1	0.9736	100	0.168	Contact Map
3rkoL	1	0.9757	100	0.197	Contact Map
3rkoN	1	0.929	100	0.207	Contact Map
4he8L	1	0.9736	100	0.209	Contact Map
4he8M	1	0.931	100	0.21	Contact Map
4he8N	1	0.8621	100	0.28	Contact Map
4he8K	1	0.1866	29.6	0.965	Contact Map
3rkoK	1	0.1947	26.5	0.966	Contact Map
3wu2X	1	0.0751	7.5	0.973	Contact Map
3wdoA	1	0.8438	4.7	0.976	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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