YWRD - BACSU - GREMLIN Contacts

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YWRD - Putative gamma-glutamyltransferase YwrD

UniProt:	O05218	Sequences: MNKSVIGTKQMVVSPHYLASQAGNRILDKGGNAFDAAVAVSACLAVVYPHMTGLGGDSFWLTFHQETKAVKVYNGSGRSGKNVTRDVYKGKSAIPLRGIDSAITVPGMVDSWDAVLKEYGRLSLADVLEPARDYAQNGFPVSADQCRHTEKNIELLASTPYTADIFTRRGKAPVPGERFVQKELADSLNLIAEKGRSAFYEGDLAQRIVSHLQNNGSYMTIDDFKAHRGEWAAPVSSDYRGYSVYQAPPNSQGFTGLLTLNILENYDFTQIEHGSFEYYHVLVEALKKSFLDRDAVLTDPAFADIPLERLLDKRYAKQLAEEIGYLAIPAESRPVGSDTAYAAVIDADGNAVSFIQSLYFEFGSAVTAGDTGILLQNRGSFFSLDENHVNTLEPRKRTFHTLMPAMVCKGGKPKILYGTQGGEGQPQTQTAIITRMLDYGMHPQQAISEPRWVWGRTWGEEYEGLRVEGRFTDKTIQKLKDSGHLVEVVGDYDPLMGQAAAIKVDEEGFLQGGADPRGDGAAVGI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	525 (503)
Sequences:	5267 (3669)
Seq/√Len:	163.6

ECOLI - GGT
BACSU - YWRD GGT
SULSO - Q97TX5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
136_Q	189_N	6.912	1.00
197_S	201_E	4.170	1.00
265_N	320_A	4.127	1.00
206_Q	221_I	3.690	1.00
29_K	126_D	3.685	1.00
133_D	137_N	3.540	1.00
261_N	316_A	3.465	1.00
11_M	512_G	3.456	1.00
14_S	20_S	3.106	1.00
75_G	111_S	2.970	1.00
14_S	40_V	2.907	1.00
283_V	465_L	2.684	1.00
209_V	221_I	2.680	1.00
239_Y	438_D	2.656	1.00
146_C	175_P	2.519	1.00
65_Q	350_N	2.474	1.00
261_N	313_K	2.410	1.00
442_H	445_Q	2.370	1.00
43_C	134_Y	2.314	1.00
240_R	438_D	2.297	1.00
435_R	441_M	2.277	1.00
264_E	313_K	2.260	1.00
113_D	117_K	2.255	1.00
443_P	501_A	2.255	1.00
23_G	40_V	2.216	1.00
42_A	128_L	2.214	1.00
265_N	317_K	2.208	1.00
245_Y	408_C	2.172	1.00
132_R	192_A	2.167	1.00
276_F	478_K	2.160	1.00
113_D	196_R	2.153	1.00
478_K	482_S	2.147	1.00
129_E	133_D	2.142	1.00
60_W	115_V	2.131	1.00
64_H	67_T	2.124	1.00
277_E	482_S	2.120	1.00
114_A	229_G	2.116	1.00
12_V	23_G	2.111	1.00
73_Y	231_W	2.094	1.00
171_K	177_E	2.094	1.00
259_T	430_T	2.089	1.00
212_L	217_S	2.083	1.00
40_V	342_A	2.064	1.00
198_A	204_L	2.061	1.00
238_D	243_S	2.047	1.00
477_Q	480_K	2.041	1.00
71_K	119_Y	2.012	1.00
351_A	416_L	1.997	1.00
236_S	243_S	1.989	1.00
324_G	327_A	1.985	1.00
9_K	347_A	1.973	1.00
280_H	484_H	1.963	1.00
118_E	231_W	1.917	1.00
447_I	501_A	1.915	1.00
433_I	437_L	1.890	1.00
189_N	193_E	1.884	1.00
407_V	433_I	1.878	1.00
194_K	198_A	1.870	1.00
190_L	203_D	1.865	1.00
183_E	370_D	1.863	1.00
201_E	225_K	1.858	1.00
174_V	177_E	1.838	1.00
345_I	510_L	1.824	1.00
25_R	28_D	1.821	1.00
72_V	247_A	1.817	1.00
262_I	285_A	1.816	1.00
222_D	226_A	1.815	1.00
190_L	194_K	1.812	1.00
69_A	233_A	1.797	1.00
34_F	115_V	1.764	1.00
125_A	193_E	1.757	1.00
190_L	198_A	1.753	1.00
206_Q	210_S	1.748	1.00
444_Q	448_S	1.746	1.00
230_E	301_A	1.734	1.00
153_I	157_A	1.733	1.00
110_D	229_G	1.731	1.00
20_S	523_V	1.729	1.00
110_D	196_R	1.726	1.00
236_S	245_Y	1.715	1.00
38_V	116_L	1.709	1.00
136_Q	186_D	1.695	1.00
345_I	351_A	1.693	1.00
109_V	191_I	1.670	1.00
81_K	226_A	1.669	1.00
114_A	117_K	1.668	1.00
207_R	371_T	1.658	1.00
25_R	29_K	1.648	1.00
21_Q	25_R	1.646	1.00
329_P	332_S	1.646	1.00
444_Q	513_G	1.645	1.00
121_R	348_D	1.641	1.00
343_A	416_L	1.624	1.00
318_Q	321_E	1.617	1.00
448_S	516_P	1.616	1.00
168_R	173_P	1.584	1.00
415_I	503_K	1.583	1.00
415_I	436_M	1.582	1.00
281_V	325_Y	1.576	1.00
116_L	127_V	1.572	1.00
12_V	40_V	1.563	1.00
47_V	139_F	1.559	1.00
209_V	213_Q	1.553	1.00
63_F	70_V	1.535	1.00
190_L	204_L	1.531	1.00
278_Y	439_Y	1.517	1.00
116_L	124_L	1.514	1.00
40_V	344_V	1.507	1.00
25_R	133_D	1.507	1.00
99_I	212_L	1.500	1.00
476_I	480_K	1.491	1.00
209_V	220_T	1.477	1.00
324_G	328_I	1.476	1.00
128_L	132_R	1.476	1.00
78_R	227_H	1.473	1.00
143_A	175_P	1.472	1.00
432_I	499_A	1.472	1.00
498_Q	518_G	1.457	1.00
140_P	178_R	1.437	1.00
161_Y	164_D	1.434	1.00
82_N	220_T	1.427	1.00
26_I	122_L	1.426	1.00
114_A	231_W	1.422	1.00
58_S	111_S	1.418	1.00
357_S	378_R	1.412	1.00
280_H	284_E	1.407	1.00
434_T	438_D	1.401	1.00
132_R	189_N	1.400	1.00
267_D	270_Q	1.399	1.00
113_D	124_L	1.383	1.00
59_F	250_N	1.380	1.00
123_S	126_D	1.379	1.00
79_S	395_R	1.375	1.00
210_S	214_N	1.368	1.00
351_A	413_P	1.367	1.00
271_I	281_V	1.363	1.00
24_N	28_D	1.361	1.00
237_S	261_N	1.359	1.00
34_F	62_T	1.357	1.00
82_N	218_Y	1.348	1.00
238_D	241_G	1.329	1.00
70_V	245_Y	1.327	1.00
464_G	487_E	1.325	1.00
284_E	287_K	1.317	1.00
63_F	68_K	1.311	1.00
98_G	366_V	1.311	1.00
319_L	322_E	1.306	1.00
212_L	219_M	1.300	1.00
110_D	197_S	1.299	1.00
503_K	511_Q	1.297	1.00
261_N	264_E	1.296	1.00
266_Y	320_A	1.295	1.00
221_I	225_K	1.293	1.00
478_K	481_D	1.290	1.00
317_K	320_A	1.289	1.00
26_I	29_K	1.287	1.00
58_S	75_G	1.287	1.00
72_V	248_P	1.284	1.00
254_F	297_L	1.268	1.00
13_V	500_A	1.264	1.00
473_D	477_Q	1.259	1.00
103_I	375_L	1.256	1.00
126_D	129_E	1.248	1.00
90_G	93_A	1.248	1.00
435_R	439_Y	1.243	1.00
226_A	395_R	1.239	1.00
476_I	486_V	1.237	1.00
436_M	503_K	1.233	1.00
203_D	206_Q	1.226	1.00
244_V	407_V	1.223	1.00
242_Y	414_K	1.220	1.00
477_Q	481_D	1.217	1.00
505_D	511_Q	1.216	1.00
26_I	127_V	1.213	1.00
74_N	232_A	1.205	1.00
105_V	219_M	1.201	1.00
431_A	451_R	1.201	1.00
201_E	205_A	1.197	1.00
467_V	476_I	1.197	1.00
368_A	371_T	1.196	1.00
22_A	43_C	1.194	1.00
288_K	322_E	1.191	1.00
34_F	352_V	1.188	1.00
81_K	395_R	1.185	1.00
385_D	388_H	1.181	1.00
32_N	121_R	1.175	1.00
368_A	375_L	1.174	1.00
61_L	72_V	1.171	1.00
168_R	177_E	1.168	1.00
24_N	523_V	1.167	1.00
71_K	118_E	1.166	1.00
259_T	285_A	1.157	1.00
441_M	449_E	1.155	1.00
409_K	412_K	1.148	1.00
279_Y	283_V	1.146	1.00
435_R	449_E	1.142	1.00
159_T	162_T	1.140	1.00
263_L	430_T	1.137	1.00
73_Y	229_G	1.131	1.00
34_F	350_N	1.119	1.00
29_K	122_L	1.118	1.00
73_Y	115_V	1.111	1.00
164_D	183_E	1.109	1.00
504_V	510_L	1.105	1.00
63_F	408_C	1.102	1.00
259_T	286_L	1.098	1.00
63_F	67_T	1.097	1.00
242_Y	437_L	1.096	1.00
267_D	271_I	1.095	1.00
284_E	484_H	1.091	1.00
160_P	164_D	1.086	1.00
222_D	225_K	1.084	1.00
71_K	231_W	1.083	1.00
173_P	177_E	1.082	1.00
62_T	115_V	1.078	0.99
408_C	413_P	1.076	0.99
277_E	325_Y	1.075	0.99
78_R	395_R	1.074	0.99
302_F	396_K	1.072	0.99
276_F	475_T	1.072	0.99
436_M	443_P	1.070	0.99
237_S	313_K	1.068	0.99
257_L	403_M	1.066	0.99
266_Y	281_V	1.064	0.99
109_V	196_R	1.063	0.99
342_A	354_F	1.062	0.99
116_L	121_R	1.060	0.99
272_E	275_S	1.053	0.99
414_K	503_K	1.052	0.99
73_Y	119_Y	1.051	0.99
38_V	127_V	1.050	0.99
110_D	114_A	1.046	0.99
292_D	319_L	1.045	0.99
211_H	368_A	1.045	0.99
114_A	228_R	1.044	0.99
276_F	482_S	1.043	0.99
313_K	317_K	1.042	0.99
187_S	373_I	1.039	0.99
116_L	123_S	1.038	0.99
25_R	130_P	1.037	0.99
393_E	396_K	1.037	0.99
279_Y	475_T	1.037	0.99
26_I	39_A	1.034	0.99
14_S	23_G	1.033	0.99
99_I	215_N	1.032	0.99
38_V	112_W	1.031	0.99
136_Q	182_K	1.030	0.99
292_D	315_Y	1.029	0.99
19_A	44_L	1.029	0.99
37_A	352_V	1.026	0.99
114_A	118_E	1.026	0.99
443_P	513_G	1.024	0.99
163_A	167_T	1.023	0.99
74_N	250_N	1.022	0.99
129_E	132_R	1.021	0.99
255_T	297_L	1.020	0.99
219_M	224_F	1.018	0.99
417_Y	432_I	1.015	0.99
124_L	127_V	1.014	0.99
124_L	128_L	1.012	0.99
81_K	222_D	1.012	0.99
60_W	111_S	1.011	0.99
278_Y	282_L	1.010	0.99
85_R	391_T	1.010	0.99
413_P	416_L	1.004	0.99
341_Y	353_S	1.003	0.99
329_P	333_R	1.000	0.99
243_S	408_C	0.997	0.99
186_D	189_N	0.995	0.99
258_L	292_D	0.993	0.99
512_G	522_A	0.991	0.99
146_C	174_V	0.989	0.99
107_G	227_H	0.989	0.99
275_S	278_Y	0.986	0.99
464_G	485_L	0.984	0.99
476_I	488_V	0.981	0.99
83_V	87_V	0.979	0.99
207_R	210_S	0.978	0.99
268_F	271_I	0.975	0.99
187_S	371_T	0.973	0.99
76_S	250_N	0.972	0.99
10_Q	27_L	0.972	0.99
26_I	126_D	0.970	0.99
26_I	130_P	0.970	0.99
41_S	356_Q	0.964	0.99
7_G	11_M	0.962	0.99
303_A	306_P	0.961	0.99
205_A	224_F	0.959	0.99
358_L	374_L	0.957	0.99
244_V	260_L	0.955	0.99
204_L	207_R	0.954	0.99
203_D	207_R	0.954	0.99
37_A	344_V	0.948	0.99
16_H	47_V	0.948	0.99
242_Y	409_K	0.947	0.99
85_R	393_E	0.945	0.99
45_A	184_L	0.943	0.99
268_F	434_T	0.942	0.99
345_I	502_I	0.942	0.99
103_I	366_V	0.938	0.99
419_T	428_T	0.935	0.99
11_M	510_L	0.934	0.99
110_D	113_D	0.932	0.99
412_K	504_V	0.930	0.98
424_G	428_T	0.927	0.98
467_V	486_V	0.926	0.98
381_F	423_E	0.925	0.98
262_I	265_N	0.924	0.98
341_Y	418_G	0.924	0.98
259_T	289_S	0.923	0.98
351_A	406_M	0.919	0.98
409_K	414_K	0.919	0.98
145_Q	149_T	0.917	0.98
15_P	48_Y	0.917	0.98
387_N	391_T	0.917	0.98
42_A	109_V	0.916	0.98
187_S	204_L	0.913	0.98
207_R	370_D	0.908	0.98
150_E	174_V	0.905	0.98
75_G	354_F	0.904	0.98
13_V	514_A	0.904	0.98
122_L	126_D	0.903	0.98
240_R	266_Y	0.903	0.98
165_I	181_Q	0.902	0.98
475_T	478_K	0.901	0.98
21_Q	28_D	0.900	0.98
205_A	221_I	0.899	0.98
416_L	502_I	0.898	0.98
89_K	386_E	0.897	0.98
136_Q	185_A	0.896	0.98
181_Q	373_I	0.894	0.98
22_A	39_A	0.889	0.98
447_I	499_A	0.888	0.98
7_G	10_Q	0.888	0.98
22_A	131_A	0.886	0.98
103_I	364_S	0.886	0.98
18_L	22_A	0.884	0.98
186_D	193_E	0.883	0.98
262_I	320_A	0.883	0.98
141_V	146_C	0.880	0.98
13_V	502_I	0.879	0.98
150_E	153_I	0.878	0.98
390_N	396_K	0.878	0.98
346_D	350_N	0.876	0.98
279_Y	471_F	0.875	0.98
209_V	212_L	0.873	0.98
467_V	471_F	0.873	0.98
383_S	386_E	0.871	0.98
208_I	375_L	0.866	0.98
278_Y	434_T	0.861	0.98
171_K	174_V	0.860	0.97
211_H	214_N	0.858	0.97
262_I	323_I	0.858	0.97
191_I	196_R	0.855	0.97
11_M	502_I	0.854	0.97
472_T	476_I	0.852	0.97
116_L	122_L	0.852	0.97
288_K	319_L	0.851	0.97
260_L	433_I	0.850	0.97
417_Y	501_A	0.850	0.97
407_V	415_I	0.850	0.97
340_A	356_Q	0.848	0.97
427_Q	453_V	0.846	0.97
52_T	356_Q	0.846	0.97
168_R	171_K	0.842	0.97
302_F	393_E	0.841	0.97
83_V	218_Y	0.840	0.97
79_S	83_V	0.836	0.97
256_G	430_T	0.833	0.97
146_C	150_E	0.833	0.97
383_S	391_T	0.832	0.97
480_K	485_L	0.831	0.97
143_A	147_R	0.831	0.97
46_V	135_A	0.830	0.97
186_D	190_L	0.828	0.97
313_K	316_A	0.828	0.97
275_S	439_Y	0.828	0.97
238_D	264_E	0.828	0.97
277_E	281_V	0.827	0.97
43_C	47_V	0.825	0.97
184_L	188_L	0.812	0.96
89_K	93_A	0.811	0.96
46_V	131_A	0.806	0.96
64_H	71_K	0.804	0.96
441_M	445_Q	0.802	0.96
298_T	398_T	0.801	0.96
405_A	417_Y	0.799	0.96
204_L	373_I	0.797	0.96
73_Y	114_A	0.796	0.96
83_V	88_Y	0.795	0.96
73_Y	118_E	0.791	0.96
466_R	487_E	0.790	0.96
122_L	127_V	0.786	0.96
211_H	215_N	0.785	0.96
99_I	211_H	0.785	0.96
181_Q	184_L	0.782	0.96
262_I	316_A	0.782	0.96
315_Y	319_L	0.781	0.96
58_S	354_F	0.780	0.96
123_S	127_V	0.779	0.96
359_Y	381_F	0.779	0.96
359_Y	380_S	0.779	0.96
211_H	366_V	0.776	0.95
480_K	488_V	0.775	0.95
312_D	316_A	0.775	0.95
467_V	488_V	0.774	0.95
237_S	316_A	0.773	0.95
45_A	188_L	0.773	0.95
78_R	301_A	0.773	0.95
162_T	374_L	0.770	0.95
472_T	475_T	0.769	0.95
141_V	179_F	0.767	0.95
280_H	323_I	0.763	0.95
238_D	313_K	0.762	0.95
87_V	218_Y	0.761	0.95
86_D	89_K	0.758	0.95
23_G	344_V	0.758	0.95
243_S	411_G	0.757	0.95
286_L	430_T	0.757	0.95
27_L	344_V	0.755	0.95
240_R	264_E	0.752	0.95
212_L	375_L	0.751	0.95
234_P	245_Y	0.749	0.94
235_V	246_Q	0.748	0.94
384_L	387_N	0.747	0.94
141_V	145_Q	0.745	0.94
46_V	184_L	0.743	0.94
160_P	163_A	0.740	0.94
77_G	378_R	0.739	0.94
262_I	319_L	0.738	0.94
104_T	379_G	0.737	0.94
269_T	272_E	0.736	0.94
20_S	521_A	0.735	0.94
282_L	452_W	0.735	0.94
246_Q	405_A	0.735	0.94
215_N	366_V	0.735	0.94
212_L	215_N	0.734	0.94
18_L	47_V	0.733	0.94
78_R	230_E	0.733	0.94
57_D	77_G	0.731	0.94
279_Y	452_W	0.730	0.94
286_L	427_Q	0.727	0.94
12_V	27_L	0.726	0.94
101_S	218_Y	0.723	0.93
61_L	406_M	0.722	0.93
240_R	437_L	0.721	0.93
246_Q	429_Q	0.720	0.93
39_A	127_V	0.720	0.93
85_R	89_K	0.720	0.93
317_K	321_E	0.719	0.93
329_P	334_P	0.717	0.93
22_A	134_Y	0.715	0.93
16_H	142_S	0.713	0.93
55_G	373_I	0.713	0.93
97_R	155_L	0.713	0.93
325_Y	328_I	0.711	0.93
41_S	342_A	0.709	0.93
18_L	134_Y	0.708	0.93
385_D	391_T	0.708	0.93
277_E	478_K	0.708	0.93
198_A	203_D	0.708	0.93
183_E	186_D	0.707	0.93
246_Q	256_G	0.706	0.93
443_P	511_Q	0.706	0.93
167_T	173_P	0.705	0.93
473_D	488_V	0.705	0.93
415_I	443_P	0.705	0.93
197_S	225_K	0.704	0.92
232_A	248_P	0.703	0.92
502_I	510_L	0.700	0.92
115_V	352_V	0.700	0.92
18_L	140_P	0.700	0.92
135_A	185_A	0.699	0.92
204_L	208_I	0.699	0.92
436_M	440_G	0.696	0.92
360_F	377_N	0.695	0.92
153_I	171_K	0.694	0.92
242_Y	407_V	0.694	0.92
266_Y	323_I	0.694	0.92
62_T	352_V	0.692	0.92
106_P	375_L	0.692	0.92
182_K	186_D	0.691	0.92
162_T	367_T	0.691	0.92
20_S	40_V	0.686	0.91
132_R	136_Q	0.686	0.91
246_Q	403_M	0.685	0.91
8_T	509_F	0.684	0.91
82_N	213_Q	0.684	0.91
54_L	109_V	0.682	0.91
141_V	173_P	0.681	0.91
131_A	135_A	0.681	0.91
41_S	354_F	0.679	0.91
414_K	436_M	0.678	0.91
40_V	43_C	0.677	0.91
62_T	350_N	0.676	0.91
22_A	26_I	0.675	0.91
320_A	323_I	0.674	0.91
255_T	293_R	0.674	0.91
21_Q	523_V	0.673	0.91
368_A	373_I	0.673	0.91
269_T	440_G	0.672	0.91
208_I	224_F	0.672	0.91
42_A	124_L	0.671	0.91
18_L	21_Q	0.668	0.90
71_K	233_A	0.667	0.90
59_F	400_H	0.667	0.90
407_V	437_L	0.667	0.90
142_S	519_D	0.666	0.90
83_V	392_L	0.664	0.90
282_L	434_T	0.663	0.90
48_Y	498_Q	0.662	0.90
469_G	490_G	0.662	0.90
263_L	268_F	0.661	0.90
88_Y	98_G	0.661	0.90
406_M	413_P	0.657	0.90
376_Q	379_G	0.657	0.90
149_T	173_P	0.656	0.90
20_S	24_N	0.654	0.89
500_A	514_A	0.653	0.89
213_Q	220_T	0.653	0.89
207_R	368_A	0.653	0.89
280_H	287_K	0.652	0.89
113_D	116_L	0.652	0.89
247_A	251_S	0.651	0.89
309_R	312_D	0.650	0.89
98_G	364_S	0.649	0.89
21_Q	24_N	0.649	0.89
64_H	68_K	0.648	0.89
10_Q	24_N	0.646	0.89
237_S	264_E	0.646	0.89
108_M	356_Q	0.646	0.89
243_S	409_K	0.645	0.89
454_W	465_L	0.645	0.89
20_S	522_A	0.644	0.89
468_E	517_R	0.644	0.89
187_S	190_L	0.643	0.89
272_E	278_Y	0.642	0.89
99_I	366_V	0.641	0.88
256_G	429_Q	0.639	0.88
38_V	128_L	0.638	0.88
70_V	408_C	0.637	0.88
161_Y	211_H	0.636	0.88
447_I	513_G	0.635	0.88
443_P	447_I	0.635	0.88
43_C	131_A	0.634	0.88
280_H	482_S	0.634	0.88
343_A	502_I	0.630	0.88
34_F	64_H	0.629	0.88
273_H	441_M	0.627	0.87
417_Y	433_I	0.627	0.87
96_L	360_F	0.626	0.87
345_I	504_V	0.626	0.87
65_Q	348_D	0.626	0.87
259_T	427_Q	0.623	0.87
129_E	192_A	0.621	0.87
59_F	251_S	0.620	0.87
77_G	104_T	0.620	0.87
428_T	499_A	0.620	0.87
309_R	334_P	0.620	0.87
284_E	323_I	0.618	0.87
232_A	301_A	0.617	0.87
428_T	497_G	0.616	0.86
258_L	262_I	0.616	0.86
153_I	172_A	0.614	0.86
159_T	367_T	0.612	0.86
436_M	446_A	0.612	0.86
42_A	112_W	0.611	0.86
110_D	227_H	0.611	0.86
471_F	476_I	0.611	0.86
148_H	361_E	0.610	0.86
161_Y	369_G	0.610	0.86
235_V	297_L	0.610	0.86
166_F	181_Q	0.609	0.86
514_A	522_A	0.609	0.86
54_L	191_I	0.607	0.86
345_I	416_L	0.606	0.86
403_M	429_Q	0.606	0.86
157_A	163_A	0.606	0.86
274_G	278_Y	0.606	0.86
204_L	371_T	0.606	0.86
258_L	315_Y	0.605	0.85
213_Q	219_M	0.605	0.85
41_S	112_W	0.604	0.85
351_A	504_V	0.603	0.85
469_G	488_V	0.603	0.85
405_A	433_I	0.602	0.85
63_F	413_P	0.602	0.85
424_G	453_V	0.601	0.85
165_I	367_T	0.601	0.85
263_L	281_V	0.599	0.85
474_K	477_Q	0.599	0.85
244_V	405_A	0.598	0.85
194_K	203_D	0.597	0.85
514_A	518_G	0.596	0.85
45_A	53_G	0.595	0.85
314_R	318_Q	0.594	0.84
325_Y	482_S	0.592	0.84
48_Y	51_M	0.592	0.84
113_D	195_G	0.592	0.84
38_V	120_G	0.591	0.84
345_I	413_P	0.591	0.84
178_R	509_F	0.590	0.84
81_K	220_T	0.590	0.84
263_L	282_L	0.590	0.84
293_R	297_L	0.590	0.84
96_L	380_S	0.589	0.84
355_I	425_Q	0.589	0.84
59_F	76_S	0.589	0.84
341_Y	355_I	0.588	0.84
159_T	364_S	0.588	0.84
57_D	76_S	0.586	0.84
210_S	370_D	0.586	0.84
39_A	131_A	0.585	0.84
424_G	496_M	0.585	0.84
33_A	352_V	0.584	0.83
311_L	316_A	0.584	0.83
77_G	401_T	0.582	0.83
272_E	439_Y	0.581	0.83
26_I	40_V	0.581	0.83
44_L	340_A	0.581	0.83
431_A	435_R	0.580	0.83
45_A	52_T	0.580	0.83
414_K	504_V	0.579	0.83
271_I	278_Y	0.579	0.83
60_W	75_G	0.578	0.83
417_Y	429_Q	0.578	0.83
62_T	71_K	0.576	0.83
298_T	303_A	0.576	0.83
298_T	389_V	0.574	0.82
265_N	313_K	0.574	0.82
65_Q	68_K	0.573	0.82
22_A	25_R	0.573	0.82
67_T	70_V	0.573	0.82
64_H	69_A	0.572	0.82
434_T	439_Y	0.572	0.82
473_D	476_I	0.572	0.82
88_Y	102_A	0.570	0.82
149_T	167_T	0.570	0.82
378_R	401_T	0.569	0.82
110_D	201_E	0.569	0.82
64_H	350_N	0.568	0.82
79_S	382_F	0.568	0.82
41_S	108_M	0.567	0.82
208_I	373_I	0.566	0.81
273_H	278_Y	0.566	0.81
145_Q	179_F	0.564	0.81
175_P	178_R	0.564	0.81
271_I	275_S	0.563	0.81
309_R	332_S	0.563	0.81
285_A	323_I	0.563	0.81
128_L	192_A	0.562	0.81
78_R	81_K	0.562	0.81
258_L	316_A	0.561	0.81
255_T	307_L	0.559	0.81
285_A	289_S	0.559	0.81
15_P	340_A	0.559	0.81
256_G	297_L	0.558	0.81
209_V	219_M	0.558	0.81
10_Q	347_A	0.557	0.80
413_P	504_V	0.557	0.80
324_G	482_S	0.556	0.80
61_L	247_A	0.554	0.80
198_A	201_E	0.554	0.80
32_N	348_D	0.552	0.80
256_G	426_P	0.552	0.80
76_S	400_H	0.551	0.80
139_F	179_F	0.550	0.80
58_S	108_M	0.549	0.79
199_F	205_A	0.548	0.79
436_M	501_A	0.547	0.79
452_W	471_F	0.547	0.79
282_L	286_L	0.547	0.79
34_F	60_W	0.546	0.79
424_G	427_Q	0.544	0.79
74_N	230_E	0.543	0.79
147_R	151_K	0.543	0.79
80_G	83_V	0.543	0.79
384_L	388_H	0.542	0.79
330_A	333_R	0.541	0.79
290_F	426_P	0.541	0.79
343_A	353_S	0.540	0.78
108_M	357_S	0.540	0.78
367_T	374_L	0.540	0.78
51_M	358_L	0.538	0.78
84_T	87_V	0.536	0.78
355_I	400_H	0.536	0.78
211_H	369_G	0.532	0.77
23_G	39_A	0.531	0.77
32_N	122_L	0.531	0.77
48_Y	53_G	0.530	0.77
7_G	24_N	0.530	0.77
205_A	208_I	0.530	0.77
48_Y	52_T	0.530	0.77
19_A	43_C	0.530	0.77
381_F	401_T	0.529	0.77
280_H	325_Y	0.529	0.77
78_R	397_R	0.529	0.77
76_S	381_F	0.529	0.77
102_A	364_S	0.529	0.77
390_N	399_F	0.528	0.77
78_R	226_A	0.527	0.77
388_H	391_T	0.527	0.77
344_V	352_V	0.527	0.77
212_L	224_F	0.526	0.77
319_L	332_S	0.526	0.77
44_L	342_A	0.525	0.76
189_N	192_A	0.522	0.76
95_P	384_L	0.520	0.76
156_L	162_T	0.519	0.76
153_I	167_T	0.519	0.76
15_P	518_G	0.518	0.75
268_F	281_V	0.518	0.75
428_T	496_M	0.518	0.75
61_L	70_V	0.516	0.75
232_A	247_A	0.516	0.75
60_W	352_V	0.515	0.75
115_V	119_Y	0.515	0.75
177_E	180_V	0.514	0.75
246_Q	426_P	0.514	0.75
61_L	234_P	0.512	0.75
237_S	311_L	0.511	0.75
378_R	381_F	0.511	0.75
199_F	204_L	0.511	0.75
292_D	296_V	0.510	0.74
113_D	127_V	0.510	0.74
263_L	266_Y	0.510	0.74
64_H	70_V	0.509	0.74
26_I	344_V	0.509	0.74
282_L	285_A	0.508	0.74
54_L	373_I	0.508	0.74
291_L	319_L	0.508	0.74
218_Y	392_L	0.507	0.74
57_D	104_T	0.507	0.74
296_V	306_P	0.506	0.74
268_F	439_Y	0.506	0.74
259_T	426_P	0.506	0.74
286_L	452_W	0.506	0.74
111_S	229_G	0.506	0.74
50_H	145_Q	0.506	0.74
98_G	102_A	0.505	0.74
239_Y	437_L	0.505	0.74
146_C	172_A	0.504	0.74
296_V	310_L	0.504	0.74
183_E	187_S	0.503	0.73
191_I	198_A	0.503	0.73
104_T	376_Q	0.502	0.73
51_M	144_D	0.501	0.73
244_V	257_L	0.501	0.73
62_T	119_Y	0.501	0.73
237_S	257_L	0.501	0.73
401_T	423_E	0.501	0.73
57_D	400_H	0.500	0.73
185_A	189_N	0.500	0.73
142_S	512_G	0.500	0.73

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2e0wA	1	0.9143	100	0.021	Contact Map
2nlzA	4	0.9714	100	0.024	Contact Map
2i3oA	2	0.9562	100	0.049	Contact Map
3whrA	1	0.6571	100	0.345	Contact Map
2dg5A	1	0.64	100	0.383	Contact Map
2qmcA	1	0.64	100	0.385	Contact Map
4gdxA	1	0.6324	100	0.39	Contact Map
3g9kL	1	0.541	100	0.421	Contact Map
4gdxB	1	0.341	100	0.647	Contact Map
3whrB	1	0.341	100	0.649	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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