GREMLIN Database
PULA - Pullulanase
UniProt: C0SPA0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 718 (569)
Sequences: 6264 (4099)
Seq/√Len: 171.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
608_R689_E4.0271.00
345_E348_P4.0181.00
240_L317_E3.7751.00
262_E607_R3.5791.00
143_M153_V3.5461.00
240_L320_Q3.5311.00
208_P211_H3.4341.00
318_L322_I3.4051.00
554_A705_T3.2981.00
268_V325_L3.2231.00
558_L707_I3.1561.00
324_T327_Q3.0421.00
114_H154_T2.9351.00
558_L643_Y2.8921.00
261_K328_H2.7781.00
572_F602_D2.7541.00
278_G287_A2.7381.00
319_K397_E2.7361.00
226_S255_S2.7251.00
119_V352_T2.6681.00
258_A328_H2.6671.00
393_Y398_Y2.6001.00
202_W399_N2.5811.00
220_T225_F2.4871.00
384_R418_Y2.4761.00
424_T455_P2.4501.00
611_S615_A2.4381.00
661_H705_T2.3771.00
616_H709_Y2.3541.00
338_F390_C2.2971.00
270_L273_V2.2711.00
115_T158_D2.2181.00
558_L659_V2.1381.00
200_M323_N2.1301.00
395_L430_I2.1191.00
203_T323_N2.1141.00
205_P399_N2.1131.00
130_K176_E2.0971.00
316_T319_K2.0751.00
127_A168_I2.0641.00
679_R709_Y2.0641.00
320_Q324_T2.0401.00
126_S142_Q2.0311.00
159_L162_Y2.0121.00
680_L708_L2.0081.00
191_K195_L2.0001.00
669_E695_K1.9661.00
318_L400_V1.9551.00
324_T328_H1.9501.00
522_E569_Q1.9471.00
669_E697_T1.9361.00
553_A606_I1.9071.00
298_F390_C1.9011.00
273_V318_L1.8961.00
214_D620_R1.8961.00
260_V268_V1.8911.00
181_Y357_F1.8851.00
215_A267_H1.8811.00
257_L328_H1.8791.00
262_E603_V1.8751.00
635_T638_E1.8731.00
163_E186_T1.8531.00
119_V127_A1.8511.00
108_A115_T1.8421.00
138_G167_C1.8291.00
473_G531_D1.8291.00
423_A430_I1.8261.00
178_V185_V1.8131.00
126_S169_C1.8121.00
270_L321_M1.8121.00
571_F591_L1.8101.00
321_M325_L1.8051.00
343_K366_P1.7981.00
128_A169_C1.7941.00
244_E324_T1.7891.00
350_E353_V1.7851.00
193_V196_R1.7721.00
167_C176_E1.7701.00
168_I352_T1.7531.00
306_S317_E1.7441.00
217_I519_N1.7431.00
119_V168_I1.7421.00
318_L321_M1.7371.00
604_H607_R1.7331.00
128_A167_C1.7301.00
117_F166_F1.7271.00
612_L681_L1.7231.00
553_A565_I1.7021.00
639_H664_S1.6951.00
158_D162_Y1.6881.00
349_F353_V1.6691.00
616_H657_I1.6571.00
110_Y115_T1.6511.00
415_T419_M1.6421.00
215_A431_L1.6411.00
220_T260_V1.6361.00
323_N327_Q1.6361.00
260_V330_L1.6351.00
422_K425_K1.6231.00
228_H231_S1.6191.00
216_V610_I1.6121.00
200_M320_Q1.6071.00
376_I383_A1.6071.00
118_K152_A1.6011.00
603_V607_R1.6001.00
202_W205_P1.6001.00
125_T169_C1.5991.00
508_A549_Q1.5941.00
497_G500_G1.5881.00
600_K604_H1.5821.00
660_I670_W1.5821.00
385_K389_D1.5681.00
349_F386_F1.5601.00
510_I514_P1.5581.00
644_R656_D1.5541.00
317_E320_Q1.5521.00
557_L610_I1.5501.00
222_L242_L1.5491.00
349_F352_T1.5491.00
567_S591_L1.5461.00
132_S162_Y1.5401.00
229_E232_G1.5381.00
644_R658_I1.5371.00
595_R599_F1.5351.00
101_Y104_G1.5261.00
509_P559_A1.5261.00
225_F256_G1.5231.00
326_H401_D1.5221.00
464_N468_R1.5211.00
210_S267_H1.5201.00
605_Y684_P1.5151.00
274_N294_P1.5091.00
467_F559_A1.5081.00
115_T194_V1.5071.00
228_H232_G1.5051.00
223_R227_I1.4981.00
274_N390_C1.4961.00
182_A192_G1.4951.00
220_T268_V1.4881.00
672_L696_K1.4841.00
592_D595_R1.4791.00
382_M385_K1.4771.00
275_D302_G1.4771.00
393_Y397_E1.4751.00
185_V296_H1.4721.00
549_Q572_F1.4721.00
204_A207_K1.4711.00
141_F153_V1.4651.00
698_V708_L1.4531.00
118_K150_V1.4461.00
395_L423_A1.4401.00
111_T154_T1.4401.00
128_A142_Q1.4381.00
204_A399_N1.4381.00
396_E426_A1.4361.00
267_H333_I1.4341.00
215_A266_T1.4311.00
660_I700_V1.4261.00
414_D417_L1.4211.00
349_F354_P1.4181.00
300_P393_Y1.3981.00
244_E255_S1.3951.00
300_P318_L1.3931.00
659_V707_I1.3871.00
333_I433_F1.3731.00
605_Y682_C1.3631.00
632_E635_T1.3511.00
586_D589_N1.3431.00
590_Q594_D1.3421.00
667_S699_A1.3331.00
200_M399_N1.3301.00
106_L118_K1.3291.00
128_A140_T1.3241.00
350_E354_P1.3191.00
239_Y305_A1.3181.00
360_H364_G1.3111.00
243_T320_Q1.3061.00
110_Y160_H1.3041.00
375_D410_I1.2981.00
377_A380_R1.2911.00
420_K424_T1.2851.00
185_V299_A1.2841.00
631_L658_I1.2821.00
392_V422_K1.2801.00
235_N244_E1.2781.00
155_V158_D1.2771.00
200_M319_K1.2761.00
414_D418_Y1.2731.00
222_L270_L1.2711.00
548_R703_I1.2711.00
361_D365_M1.2701.00
629_R646_Y1.2671.00
546_R549_Q1.2641.00
106_L150_V1.2631.00
351_K354_P1.2611.00
116_V154_T1.2591.00
318_L398_Y1.2581.00
260_V264_G1.2551.00
165_L176_E1.2541.00
680_L683_D1.2521.00
105_E118_K1.2471.00
243_T324_T1.2471.00
655_K709_Y1.2431.00
608_R688_Q1.2431.00
672_L678_Y1.2401.00
140_T167_C1.2361.00
450_A453_N1.2341.00
225_F242_L1.2341.00
576_Q588_I1.2311.00
604_H608_R1.2301.00
541_N574_T1.2291.00
647_D654_W1.2241.00
498_I637_K1.2221.00
496_H499_A1.2201.00
130_K167_C1.2201.00
257_L324_T1.2201.00
425_K428_P1.2191.00
642_A660_I1.2071.00
590_Q593_W1.2061.00
553_A609_L1.2031.00
300_P394_W1.2021.00
131_L141_F1.2021.00
220_T242_L1.1981.00
296_H299_A1.1871.00
132_S163_E1.1781.00
127_A352_T1.1781.00
640_L700_V1.1721.00
388_A422_K1.1701.00
242_L321_M1.1641.00
419_M432_L1.1621.00
418_Y422_K1.1611.00
413_I417_L1.1611.00
160_H199_Q1.1581.00
167_C174_W1.1561.00
216_V614_K1.1561.00
418_Y421_E1.1541.00
188_N286_D1.1541.00
508_A540_E1.1541.00
518_I563_P1.1521.00
497_G501_S1.1511.00
258_A262_E1.1481.00
468_R503_G1.1431.00
551_L705_T1.1401.00
612_L682_C1.1391.00
565_I569_Q1.1361.00
621_L648_L1.1361.00
504_W641_I1.1341.00
132_S191_K1.1331.00
169_C174_W1.1311.00
122_P149_G1.1301.00
388_A419_M1.1221.00
105_E116_V1.1211.00
220_T567_S1.1161.00
129_V153_V1.1131.00
120_W382_M1.1111.00
472_K503_G1.1071.00
344_R348_P1.1061.00
596_R603_V1.1061.00
116_V152_A1.1011.00
242_L325_L1.0991.00
267_H331_R1.0941.00
391_V419_M1.0941.00
189_G193_V1.0871.00
415_T420_K1.0871.00
657_I709_Y1.0821.00
605_Y609_L1.0801.00
115_T159_L1.0781.00
533_M553_A1.0771.00
495_M498_I1.0721.00
263_L603_V1.0681.00
258_A261_K1.0681.00
378_S387_I1.0671.00
546_R550_R1.0651.00
203_T327_Q1.0631.00
207_K399_N1.0631.00
275_D301_E1.0631.00
597_E600_K1.0611.00
508_A512_P1.0611.00
370_T410_I1.0591.00
257_L325_L1.0591.00
612_L616_H1.0551.00
125_T171_N1.0551.00
163_E193_V1.0520.99
182_A185_V1.0490.99
610_I614_K1.0480.99
325_L330_L1.0420.99
199_Q316_T1.0390.99
102_Y181_Y1.0350.99
224_D288_Y1.0310.99
657_I707_I1.0280.99
341_V358_F1.0140.99
244_E258_A1.0130.99
274_N334_L1.0130.99
550_R601_E1.0130.99
608_R611_S1.0120.99
367_S375_D1.0110.99
619_F657_I1.0100.99
612_L707_I1.0100.99
197_P319_K1.0090.99
578_V584_S1.0060.99
238_K241_A1.0020.99
225_F259_Y0.9980.99
593_W596_R0.9970.99
200_M203_T0.9950.99
360_H363_C0.9950.99
221_H271_L0.9910.99
141_F155_V0.9910.99
549_Q602_D0.9840.99
294_P297_F0.9800.99
240_L243_T0.9760.99
640_L643_Y0.9750.99
660_I708_L0.9720.99
575_K581_S0.9700.99
681_L709_Y0.9700.99
554_A684_P0.9680.99
205_P208_P0.9650.99
244_E320_Q0.9630.99
643_Y659_V0.9620.99
421_E448_K0.9590.99
451_L484_A0.9540.99
233_M236_K0.9530.99
495_M501_S0.9530.99
129_V155_V0.9510.99
184_A195_L0.9500.99
548_R551_L0.9460.99
204_A323_N0.9450.99
133_H137_S0.9440.99
235_N240_L0.9420.99
522_E552_A0.9410.99
359_R377_A0.9410.99
468_R471_V0.9400.99
216_V557_L0.9400.99
222_L239_Y0.9370.99
537_L543_S0.9370.99
600_K603_V0.9360.99
109_V183_K0.9350.99
108_A166_F0.9340.99
231_S256_G0.9290.99
160_H196_R0.9290.99
683_D686_G0.9280.99
581_S588_I0.9240.99
640_L668_V0.9240.99
192_G196_R0.9240.99
220_T256_G0.9210.99
183_K197_P0.9200.99
392_V427_K0.9190.99
553_A602_D0.9180.99
442_P449_A0.9160.99
607_R611_S0.9150.99
273_V334_L0.9140.99
588_I593_W0.9130.99
344_R347_S0.9130.99
557_L565_I0.9120.99
667_S702_G0.9120.99
656_D710_L0.9090.99
633_C641_I0.9080.99
239_Y300_P0.9080.99
660_I706_V0.9040.98
558_L661_H0.9030.98
640_L645_L0.9030.98
540_E544_R0.9020.98
205_P323_N0.9020.98
698_V706_V0.9000.98
466_M552_A0.8980.98
356_Y359_R0.8970.98
184_A193_V0.8960.98
183_K393_Y0.8950.98
471_V555_I0.8940.98
419_M422_K0.8940.98
131_L162_Y0.8900.98
551_L661_H0.8850.98
473_G529_F0.8840.98
680_L686_G0.8830.98
298_F386_F0.8810.98
210_S329_G0.8800.98
192_G195_L0.8770.98
391_V403_F0.8760.98
554_A558_L0.8760.98
147_E152_A0.8740.98
108_A117_F0.8710.98
196_R199_Q0.8690.98
181_Y389_D0.8680.98
117_F129_V0.8660.98
259_Y603_V0.8630.98
495_M499_A0.8620.98
269_E463_F0.8600.98
297_F376_I0.8540.98
298_F389_D0.8520.98
191_K196_R0.8510.98
133_H136_K0.8480.98
144_T153_V0.8480.98
449_A453_N0.8460.98
222_L273_V0.8430.98
391_V405_F0.8410.98
514_P528_T0.8400.98
230_N233_M0.8380.97
192_G197_P0.8380.97
361_D367_S0.8360.97
226_S237_G0.8360.97
554_A605_Y0.8360.97
125_T170_N0.8340.97
609_L682_C0.8340.97
381_R384_R0.8330.97
177_T352_T0.8290.97
671_R695_K0.8290.97
104_G397_E0.8290.97
540_E543_S0.8290.97
366_P371_G0.8280.97
680_L706_V0.8230.97
421_E425_K0.8220.97
544_R548_R0.8220.97
278_G293_N0.8220.97
395_L403_F0.8210.97
203_T399_N0.8160.97
334_L400_V0.8140.97
162_Y194_V0.8140.97
278_G286_D0.8120.97
396_E427_K0.8120.97
580_N583_Q0.8100.97
577_G580_N0.8090.97
618_A657_I0.8080.97
565_I606_I0.8080.97
368_N410_I0.8070.97
384_R414_D0.8050.97
451_L454_A0.8050.97
359_R364_G0.8040.97
226_S256_G0.8040.97
667_S697_T0.8020.97
346_N351_K0.8020.97
112_A154_T0.8010.97
490_S493_A0.8010.97
392_V426_A0.7980.97
130_K140_T0.7950.97
189_G195_L0.7940.97
158_D194_V0.7930.96
186_T189_G0.7930.96
553_A569_Q0.7920.96
532_K536_A0.7900.96
494_V497_G0.7900.96
554_A707_I0.7890.96
623_S626_D0.7890.96
618_A621_L0.7880.96
123_A353_V0.7870.96
545_K574_T0.7840.96
276_F294_P0.7830.96
546_R599_F0.7820.96
647_D655_K0.7790.96
508_A572_F0.7790.96
203_T207_K0.7790.96
265_V330_L0.7780.96
134_P137_S0.7780.96
122_P356_Y0.7760.96
392_V396_E0.7750.96
622_R625_A0.7740.96
294_P390_C0.7740.96
220_T270_L0.7700.96
214_D614_K0.7690.96
665_P703_I0.7680.96
535_F544_R0.7670.96
588_I591_L0.7650.96
408_L434_G0.7620.96
229_E233_M0.7620.96
160_H195_L0.7610.96
513_E528_T0.7590.96
117_F194_V0.7590.96
316_T320_Q0.7580.95
257_L261_K0.7550.95
350_E355_G0.7540.95
235_N241_A0.7540.95
228_H233_M0.7520.95
496_H500_G0.7510.95
688_Q691_P0.7510.95
616_H655_K0.7500.95
105_E109_V0.7500.95
102_Y105_E0.7470.95
266_T330_L0.7460.95
541_N545_K0.7460.95
420_K432_L0.7450.95
417_L421_E0.7390.95
297_F386_F0.7390.95
438_D444_P0.7340.95
619_F622_R0.7340.95
554_A661_H0.7320.95
146_L152_A0.7280.94
305_A308_P0.7270.94
165_L191_K0.7260.94
533_M544_R0.7250.94
627_I631_L0.7240.94
274_N400_V0.7240.94
183_K397_E0.7240.94
121_A149_G0.7220.94
216_V265_V0.7220.94
616_H654_W0.7200.94
212_P215_A0.7200.94
701_N704_G0.7190.94
228_H237_G0.7190.94
127_A166_F0.7190.94
185_V275_D0.7170.94
228_H590_Q0.7170.94
376_I386_F0.7160.94
186_T193_V0.7150.94
641_I645_L0.7130.94
468_R472_K0.7110.94
369_G375_D0.7100.94
423_A432_L0.7080.94
259_Y571_F0.7080.94
587_S590_Q0.7070.93
323_N399_N0.7060.93
143_M166_F0.7050.93
604_H688_Q0.7040.93
642_A645_L0.7030.93
258_A324_T0.7030.93
223_R304_Y0.7030.93
575_K592_D0.7010.93
550_R602_D0.7010.93
202_W207_K0.7010.93
620_R623_S0.6980.93
495_M500_G0.6950.93
237_G255_S0.6940.93
266_T614_K0.6930.93
601_E604_H0.6920.93
449_A452_A0.6920.93
364_G377_A0.6910.93
555_I661_H0.6910.93
260_V325_L0.6890.93
298_F393_Y0.6880.93
109_V116_V0.6860.92
218_Y570_E0.6860.92
111_T114_H0.6860.92
318_L334_L0.6850.92
348_P353_V0.6850.92
575_K589_N0.6850.92
682_C687_F0.6850.92
633_C643_Y0.6850.92
198_D397_E0.6840.92
278_G303_S0.6830.92
202_W206_L0.6820.92
550_R605_Y0.6810.92
226_S241_A0.6810.92
535_F548_R0.6800.92
454_A457_M0.6800.92
643_Y647_D0.6790.92
277_A295_L0.6780.92
320_Q323_N0.6780.92
422_K427_K0.6770.92
336_V391_V0.6760.92
268_V321_M0.6760.92
189_G192_G0.6760.92
423_A427_K0.6740.92
496_H501_S0.6730.92
356_Y380_R0.6720.92
675_D678_Y0.6710.92
415_T422_K0.6710.92
161_G193_V0.6700.92
604_H689_E0.6690.91
622_R626_D0.6690.91
142_Q151_Y0.6680.91
489_E493_A0.6670.91
188_N302_G0.6650.91
178_V182_A0.6640.91
155_V159_L0.6640.91
573_R591_L0.6640.91
589_N592_D0.6630.91
494_V500_G0.6630.91
126_S167_C0.6630.91
406_D525_D0.6630.91
263_L610_I0.6610.91
203_T206_L0.6610.91
685_S691_P0.6590.91
646_Y656_D0.6590.91
639_H642_A0.6580.91
603_V606_I0.6570.91
331_R431_L0.6570.91
123_A352_T0.6570.91
521_V552_A0.6570.91
675_D694_I0.6540.91
424_T431_L0.6540.91
106_L181_Y0.6540.91
144_T152_A0.6520.90
239_Y321_M0.6500.90
123_A355_G0.6500.90
472_K496_H0.6490.90
348_P351_K0.6480.90
264_G611_S0.6470.90
415_T421_E0.6470.90
295_L342_Y0.6460.90
669_E699_A0.6450.90
422_K426_A0.6440.90
584_S588_I0.6440.90
498_I501_S0.6440.90
178_V192_G0.6430.90
268_V332_V0.6430.90
461_G562_V0.6410.90
642_A647_D0.6410.90
658_I678_Y0.6410.90
166_F181_Y0.6380.89
240_L244_E0.6380.89
632_E642_A0.6360.89
631_L645_L0.6350.89
549_Q553_A0.6340.89
359_R363_C0.6340.89
633_C645_L0.6330.89
416_V419_M0.6330.89
384_R415_T0.6320.89
443_L452_A0.6310.89
448_K452_A0.6300.89
260_V265_V0.6300.89
275_D303_S0.6300.89
463_F564_F0.6290.89
201_K204_A0.6290.89
319_K393_Y0.6280.89
348_P354_P0.6280.89
596_R599_F0.6280.89
186_T190_E0.6270.89
190_E295_L0.6260.89
301_E304_Y0.6250.88
345_E351_K0.6240.88
231_S255_S0.6230.88
120_W380_R0.6210.88
573_R589_N0.6210.88
640_L670_W0.6200.88
199_Q319_K0.6190.88
574_T595_R0.6190.88
555_I559_A0.6180.88
256_G260_V0.6180.88
101_Y426_A0.6170.88
657_I681_L0.6170.88
376_I411_L0.6160.88
239_Y243_T0.6160.88
589_N593_W0.6160.88
586_D590_Q0.6160.88
630_H633_C0.6160.88
208_P331_R0.6160.88
643_Y646_Y0.6160.88
395_L427_K0.6140.88
450_A454_A0.6140.88
546_R601_E0.6140.88
110_Y113_D0.6130.88
602_D605_Y0.6120.87
686_G691_P0.6120.87
416_V460_I0.6110.87
660_I698_V0.6110.87
684_P689_E0.6110.87
524_H528_T0.6110.87
387_I411_L0.6080.87
197_P200_M0.6080.87
552_A555_I0.6070.87
546_R602_D0.6070.87
499_A503_G0.6070.87
271_L567_S0.6060.87
340_H406_D0.6050.87
473_G476_F0.6050.87
465_D527_H0.6040.87
581_S589_N0.6030.87
212_P461_G0.6030.87
664_S668_V0.6030.87
190_E193_V0.6020.87
631_L634_L0.6020.87
343_K371_G0.6010.86
209_F212_P0.6010.86
683_D687_F0.6010.86
654_W657_I0.6010.86
639_H645_L0.6010.86
231_S235_N0.6010.86
193_V197_P0.6000.86
265_V570_E0.6000.86
188_N236_K0.5990.86
335_D406_D0.5990.86
255_S258_A0.5980.86
322_I400_V0.5970.86
102_Y389_D0.5970.86
527_H531_D0.5960.86
685_S701_N0.5960.86
566_H573_R0.5960.86
170_N173_E0.5940.86
241_A321_M0.5940.86
585_S590_Q0.5930.86
108_A194_V0.5930.86
201_K205_P0.5930.86
665_P702_G0.5920.86
381_R385_K0.5910.86
345_E349_F0.5910.86
571_F603_V0.5900.85
494_V501_S0.5900.85
606_I610_I0.5890.85
367_S410_I0.5880.85
467_F470_A0.5880.85
202_W208_P0.5870.85
378_S412_D0.5860.85
120_W356_Y0.5860.85
360_H366_P0.5850.85
414_D425_K0.5850.85
183_K398_Y0.5840.85
700_V706_V0.5840.85
535_F545_K0.5840.85
319_K398_Y0.5830.85
421_E424_T0.5830.85
113_D154_T0.5820.85
225_F593_W0.5810.85
417_L420_K0.5800.85
667_S701_N0.5790.84
640_L646_Y0.5780.84
611_S614_K0.5780.84
204_A327_Q0.5770.84
404_R435_E0.5760.84
554_A609_L0.5740.84
201_K323_N0.5740.84
582_Y585_S0.5730.84
191_K197_P0.5730.84
121_A124_A0.5730.84
276_F301_E0.5720.84
423_A426_A0.5700.83
293_N372_V0.5700.83
406_D435_E0.5700.83
228_H256_G0.5690.83
671_R693_E0.5680.83
196_R316_T0.5670.83
349_F383_A0.5670.83
222_L257_L0.5670.83
563_P613_R0.5670.83
452_A462_F0.5660.83
449_A454_A0.5650.83
232_G235_N0.5640.83
608_R682_C0.5630.83
359_R375_D0.5620.83
361_D364_G0.5610.83
491_A494_V0.5590.82
658_I708_L0.5590.82
453_N457_M0.5590.82
578_V583_Q0.5590.82
618_A623_S0.5590.82
452_A457_M0.5580.82
627_I630_H0.5580.82
671_R697_T0.5570.82
412_D417_L0.5560.82
232_G236_K0.5550.82
495_M502_S0.5550.82
258_A325_L0.5550.82
352_T355_G0.5550.82
680_L698_V0.5540.82
115_T160_H0.5540.82
585_S588_I0.5530.82
404_R525_D0.5520.82
163_E191_K0.5520.82
448_K451_L0.5510.81
211_H214_D0.5500.81
547_S550_R0.5500.81
369_G410_I0.5500.81
607_R610_I0.5500.81
360_H365_M0.5490.81
341_V376_I0.5480.81
594_D598_T0.5480.81
191_K194_V0.5480.81
228_H255_S0.5460.81
238_K317_E0.5450.81
235_N306_S0.5440.81
422_K428_P0.5440.81
384_R388_A0.5440.81
388_A418_Y0.5440.81
666_D702_G0.5440.81
437_W468_R0.5430.80
232_G255_S0.5430.80
424_T432_L0.5430.80
129_V166_F0.5420.80
414_D421_E0.5420.80
170_N175_M0.5420.80
326_H332_V0.5410.80
233_M241_A0.5410.80
409_G437_W0.5400.80
627_I645_L0.5400.80
619_F623_S0.5390.80
449_A455_P0.5380.80
536_A539_Q0.5380.80
542_D704_G0.5380.80
424_T448_K0.5370.80
99_E102_Y0.5360.80
238_K242_L0.5360.80
579_E583_Q0.5360.80
297_F390_C0.5350.79
293_N342_Y0.5350.79
465_D469_D0.5350.79
347_S354_P0.5350.79
497_G502_S0.5340.79
367_S370_T0.5340.79
353_V360_H0.5340.79
493_A496_H0.5330.79
208_P212_P0.5330.79
339_N407_L0.5320.79
347_S351_K0.5320.79
130_K165_L0.5320.79
522_E533_M0.5320.79
369_G441_T0.5310.79
686_G689_E0.5310.79
544_R703_I0.5310.79
267_H330_L0.5300.79
419_M428_P0.5290.79
319_K399_N0.5290.79
489_E492_Q0.5290.79
493_A497_G0.5280.79
632_E640_L0.5280.79
298_F338_F0.5270.78
169_C173_E0.5260.78
521_V524_H0.5260.78
391_V423_A0.5260.78
499_A502_S0.5250.78
687_F691_P0.5250.78
346_N350_E0.5250.78
378_S415_T0.5240.78
188_N301_E0.5240.78
464_N517_S0.5240.78
346_N349_F0.5230.78
439_L442_P0.5230.78
348_P352_T0.5220.78
683_D698_V0.5210.78
416_V454_A0.5200.78
413_I420_K0.5190.77
207_K331_R0.5190.77
198_D316_T0.5190.77
287_A588_I0.5180.77
123_A356_Y0.5180.77
121_A353_V0.5180.77
424_T427_K0.5160.77
682_C690_D0.5160.77
633_C639_H0.5140.77
633_C636_L0.5130.77
155_V162_Y0.5130.77
223_R586_D0.5120.76
140_T144_T0.5120.76
321_M324_T0.5120.76
273_V321_M0.5120.76
588_I592_D0.5110.76
269_E433_F0.5110.76
638_E668_V0.5100.76
440_A443_L0.5100.76
345_E352_T0.5100.76
618_A622_R0.5100.76
187_V302_G0.5070.76
642_A658_I0.5070.76
699_A702_G0.5070.76
496_H503_G0.5050.76
534_S574_T0.5050.76
470_A663_A0.5050.76
198_D201_K0.5050.76
475_T555_I0.5050.76
219_E290_W0.5030.75
126_S144_T0.5030.75
476_F531_D0.5030.75
498_I502_S0.5030.75
451_L457_M0.5020.75
126_S139_R0.5010.75
259_Y606_I0.5010.75
683_D706_V0.5010.75
326_H399_N0.5000.75
580_N588_I0.5000.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2e8yA 1 0.9916 100 0.231 Contact Map
3wdhA 1 0.9638 100 0.253 Contact Map
2wanA 1 0.9638 100 0.274 Contact Map
3fawA 1 0.9359 100 0.337 Contact Map
2ya1A 1 0.9095 100 0.337 Contact Map
4j3vA 1 0.961 100 0.341 Contact Map
2fhfA 1 0.9847 100 0.348 Contact Map
1bf2A 1 0.8036 100 0.352 Contact Map
2ya0A 1 0.8412 100 0.359 Contact Map
4j7rA 2 0.8412 100 0.361 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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