YOAE - BACSU - GREMLIN Contacts

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YOAE - Probable oxidoreductase YoaE

UniProt:	C0SP82	Sequences: MRSFATQQNGIFKSVCSLDCPDQCGLLIHKKDGKIVKVQGDPDHPVTAGNICNKVRNMTERIYDEKRLTTPLKRTGAKGQAIFEPISWKEAIDTITSRWKQLIDEEGAESILPYSFYGNMGKLTAEGMDRRFFYRMGSSQLERTICSKAGSEGYKYTMGISAGIDPEETVHTKLFIFWGINAVSTNMHQITIAQKARKKGAKIVVIDVHKNQTGRLADWFIPIKPGTDSALALGIMHILFKENLHDEAFLSEYTVGYEELREHVKQYDPEKVSTITGVSTEDIYRLAKMYGETSPSFIRIGNGPQHHDNGGMIVRTIACLPAITGQWLHTGGGAIKHNSGILEYNTNALQRPDLLKGRTPRSFNMNQLGRVLLETDPPIRSLFIYGTNPAVVAPEANKVRQGLLREDLFTVVHDLFLTETAAYADIVLPATSAFENTDFYTSYWHHYIQLQQPVIERYGESKSNTEVFRLLAEAMGFTDQELKDSDEVLIRQALDHPDNPHLAEIDYDSLTKHSFMKAKREKPLFPGELPTPSGKIELYSEKMKQDGFPALPTYTPLVTDNEHPFMYVPGPNHNFLNSTFSNNEKHIKLEKTPKLFINTKDAEKHGIVDGAPVRIWNSRGECELTAAVGEQVLPGVVVSQGLWADEQGKKQLVNALTPDRLSDMGGGATFFSGRVQIEKV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	680 (642)
Sequences:	9579 (5923)
Seq/√Len:	233.8

ECOLI - YNFE YNFF DMSA TORZ FDHF TORA BISC NAPA YDEP FDNG FDOG NUOG NARZ NARG
BACSU - YOAE NASC YYAE YJGC FDHL NARG
HALSA - DMSA
SULSO - Q97ZA1 Q97V13 Q97XX8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
70_T	85_P	5.567	1.00
607_I	626_A	4.414	1.00
93_D	474_A	4.269	1.00
614_R	678_E	3.978	1.00
462_K	470_L	3.611	1.00
242_E	288_K	3.330	1.00
614_R	621_E	3.323	1.00
601_D	635_G	3.181	1.00
270_E	280_T	3.152	1.00
98_R	101_Q	3.146	1.00
234_G	272_V	3.142	1.00
565_F	605_H	3.130	1.00
466_E	470_L	3.095	1.00
75_T	84_E	3.005	1.00
600_K	634_P	2.973	1.00
94_T	426_I	2.917	1.00
238_I	242_E	2.894	1.00
453_P	456_E	2.874	1.00
247_E	251_S	2.867	1.00
255_V	533_S	2.771	1.00
237_H	241_K	2.745	1.00
87_S	90_E	2.744	1.00
95_I	426_I	2.732	1.00
236_M	260_L	2.725	1.00
412_V	424_A	2.715	1.00
178_W	232_A	2.685	1.00
616_W	678_E	2.665	1.00
92_I	474_A	2.658	1.00
273_S	280_T	2.577	1.00
616_W	676_Q	2.543	1.00
219_W	285_R	2.523	1.00
236_M	323_I	2.510	1.00
202_K	289_M	2.506	1.00
102_L	110_S	2.462	1.00
101_Q	105_E	2.461	1.00
597_I	626_A	2.446	1.00
173_K	295_P	2.445	1.00
533_S	537_E	2.432	1.00
70_T	460_E	2.429	1.00
485_S	488_V	2.422	1.00
231_L	276_T	2.422	1.00
617_N	675_V	2.418	1.00
592_T	625_T	2.412	1.00
86_I	426_I	2.405	1.00
73_K	94_T	2.396	1.00
597_I	677_I	2.394	1.00
92_I	470_L	2.391	1.00
279_S	282_D	2.388	1.00
613_V	626_A	2.388	1.00
280_T	284_Y	2.384	1.00
604_K	634_P	2.362	1.00
205_V	217_A	2.360	1.00
282_D	285_R	2.347	1.00
616_W	621_E	2.341	1.00
602_A	628_V	2.333	1.00
268_D	271_K	2.303	1.00
243_N	247_E	2.293	1.00
245_H	250_L	2.280	1.00
73_K	426_I	2.270	1.00
73_K	86_I	2.221	1.00
171_H	330_T	2.209	1.00
240_F	257_Y	2.191	1.00
248_A	252_E	2.149	1.00
609_D	628_V	2.147	1.00
99_W	381_S	2.145	1.00
605_H	676_Q	2.085	1.00
95_I	411_V	2.070	1.00
174_L	289_M	2.045	1.00
470_L	474_A	2.012	1.00
94_T	98_R	1.993	1.00
221_I	286_L	1.982	1.00
172_T	175_F	1.978	1.00
380_R	407_D	1.967	1.00
595_L	637_V	1.963	1.00
607_I	613_V	1.958	1.00
221_I	278_V	1.942	1.00
285_R	289_M	1.931	1.00
102_L	381_S	1.918	1.00
395_E	659_D	1.913	1.00
86_I	94_T	1.907	1.00
595_L	613_V	1.897	1.00
85_P	460_E	1.896	1.00
231_L	283_I	1.890	1.00
219_W	282_D	1.890	1.00
174_L	204_V	1.889	1.00
614_R	623_E	1.858	1.00
595_L	615_I	1.847	1.00
612_P	623_E	1.838	1.00
458_Y	461_S	1.834	1.00
237_H	269_P	1.826	1.00
196_A	201_A	1.815	1.00
383_F	413_H	1.811	1.00
245_H	257_Y	1.809	1.00
506_D	509_S	1.793	1.00
609_D	627_A	1.792	1.00
595_L	639_S	1.792	1.00
624_L	639_S	1.790	1.00
565_F	637_V	1.786	1.00
597_I	637_V	1.781	1.00
27_L	42_P	1.769	1.00
240_F	261_R	1.766	1.00
197_R	218_D	1.758	1.00
417_L	421_A	1.754	1.00
608_V	611_A	1.748	1.00
73_K	84_E	1.729	1.00
227_T	275_I	1.726	1.00
600_K	603_E	1.720	1.00
93_D	97_S	1.706	1.00
637_V	675_V	1.692	1.00
244_L	291_G	1.685	1.00
262_E	265_K	1.673	1.00
219_W	289_M	1.672	1.00
509_S	513_H	1.670	1.00
242_E	284_Y	1.668	1.00
329_H	332_G	1.649	1.00
69_T	459_G	1.641	1.00
206_I	231_L	1.639	1.00
238_I	288_K	1.635	1.00
272_V	283_I	1.632	1.00
238_I	284_Y	1.632	1.00
241_K	265_K	1.616	1.00
437_T	453_P	1.610	1.00
290_Y	296_S	1.606	1.00
86_I	90_E	1.599	1.00
470_L	473_E	1.593	1.00
406_E	410_T	1.584	1.00
290_Y	324_T	1.581	1.00
288_K	292_E	1.571	1.00
72_L	427_V	1.566	1.00
273_S	279_S	1.565	1.00
570_G	638_V	1.561	1.00
238_I	269_P	1.559	1.00
612_P	625_T	1.557	1.00
110_S	380_R	1.539	1.00
25_G	44_H	1.538	1.00
244_L	288_K	1.518	1.00
239_L	291_G	1.517	1.00
76_G	81_A	1.505	1.00
250_L	257_Y	1.498	1.00
431_T	463_S	1.488	1.00
100_K	104_D	1.484	1.00
239_L	245_H	1.482	1.00
90_E	94_T	1.478	1.00
97_S	101_Q	1.476	1.00
254_T	538_L	1.473	1.00
596_F	629_G	1.470	1.00
240_F	264_V	1.462	1.00
176_I	206_I	1.462	1.00
176_I	286_L	1.461	1.00
270_E	284_Y	1.460	1.00
273_S	283_I	1.453	1.00
95_I	428_L	1.445	1.00
12_F	30_K	1.445	1.00
484_D	488_V	1.441	1.00
230_A	275_I	1.432	1.00
106_E	380_R	1.420	1.00
231_L	286_L	1.420	1.00
219_W	286_L	1.419	1.00
75_T	82_I	1.417	1.00
99_W	411_V	1.412	1.00
622_C	639_S	1.410	1.00
259_E	262_E	1.410	1.00
255_V	537_E	1.406	1.00
565_F	601_D	1.402	1.00
60_E	585_K	1.399	1.00
261_R	265_K	1.395	1.00
400_R	404_L	1.393	1.00
323_I	538_L	1.391	1.00
72_L	85_P	1.389	1.00
487_E	491_R	1.388	1.00
237_H	265_K	1.387	1.00
29_H	39_Q	1.384	1.00
174_L	286_L	1.374	1.00
112_L	379_I	1.366	1.00
71_P	88_W	1.362	1.00
401_Q	404_L	1.361	1.00
560_D	618_S	1.358	1.00
13_K	27_L	1.355	1.00
248_A	251_S	1.347	1.00
508_D	512_K	1.339	1.00
14_S	28_I	1.338	1.00
412_V	421_A	1.334	1.00
227_T	276_T	1.332	1.00
415_L	432_S	1.330	1.00
241_K	284_Y	1.326	1.00
238_I	241_K	1.319	1.00
384_I	410_T	1.318	1.00
235_I	286_L	1.307	1.00
304_P	317_I	1.300	1.00
531_T	537_E	1.299	1.00
208_V	220_F	1.292	1.00
417_L	427_V	1.290	1.00
293_T	296_S	1.285	1.00
28_I	35_I	1.276	1.00
463_S	466_E	1.273	1.00
565_F	676_Q	1.272	1.00
238_I	244_L	1.272	1.00
452_Q	511_T	1.270	1.00
271_K	274_T	1.267	1.00
462_K	466_E	1.265	1.00
488_V	491_R	1.263	1.00
221_I	282_D	1.259	1.00
256_G	259_E	1.257	1.00
257_Y	261_R	1.257	1.00
223_I	278_V	1.246	1.00
205_V	214_G	1.242	1.00
13_K	41_D	1.240	1.00
235_I	290_Y	1.239	1.00
90_E	426_I	1.235	1.00
599_T	630_E	1.234	1.00
277_G	633_L	1.228	1.00
595_L	624_L	1.228	1.00
267_Y	272_V	1.226	1.00
326_Q	332_G	1.226	1.00
267_Y	275_I	1.222	1.00
541_E	545_Q	1.219	1.00
594_K	627_A	1.211	1.00
605_H	677_I	1.211	1.00
92_I	462_K	1.210	1.00
267_Y	271_K	1.210	1.00
375_T	398_K	1.207	1.00
35_I	62_I	1.202	1.00
100_K	103_I	1.194	1.00
370_R	374_E	1.192	1.00
96_T	474_A	1.190	1.00
103_I	111_I	1.188	1.00
639_S	653_V	1.184	1.00
598_N	634_P	1.184	1.00
173_K	294_S	1.184	1.00
168_E	171_H	1.184	1.00
28_I	38_V	1.182	1.00
236_M	264_V	1.178	1.00
413_H	430_A	1.176	1.00
240_F	245_H	1.172	1.00
473_E	478_T	1.171	1.00
223_I	227_T	1.171	1.00
395_E	398_K	1.166	1.00
235_I	287_A	1.160	1.00
247_E	261_R	1.159	1.00
173_K	293_T	1.154	1.00
369_G	373_L	1.149	1.00
562_E	676_Q	1.148	1.00
27_L	41_D	1.147	1.00
413_H	467_V	1.147	1.00
385_Y	468_F	1.144	1.00
366_N	369_G	1.144	1.00
153_G	314_V	1.141	1.00
398_K	401_Q	1.136	1.00
629_G	632_V	1.135	1.00
257_Y	323_I	1.114	1.00
244_L	292_E	1.113	1.00
175_F	201_A	1.108	1.00
74_R	83_F	1.108	1.00
562_E	618_S	1.103	1.00
232_A	317_I	1.103	1.00
466_E	473_E	1.102	1.00
401_Q	405_R	1.100	1.00
152_E	664_M	1.098	1.00
177_F	180_I	1.098	1.00
195_K	198_K	1.098	1.00
238_I	283_I	1.097	1.00
521_E	525_F	1.096	1.00
381_S	411_V	1.096	1.00
204_V	286_L	1.095	1.00
111_I	381_S	1.090	1.00
210_K	631_Q	1.087	1.00
235_I	239_L	1.081	1.00
239_L	324_T	1.080	1.00
210_K	215_R	1.080	1.00
361_R	364_N	1.078	1.00
98_R	407_D	1.076	1.00
266_Q	271_K	1.076	1.00
169_T	297_F	1.076	1.00
490_I	494_L	1.075	1.00
112_L	370_R	1.071	1.00
27_L	39_Q	1.071	1.00
176_I	235_I	1.071	1.00
178_W	206_I	1.069	1.00
431_T	461_S	1.066	1.00
596_F	627_A	1.065	1.00
567_Y	675_V	1.063	1.00
234_G	283_I	1.060	1.00
175_F	193_A	1.058	1.00
258_E	261_R	1.057	1.00
250_L	538_L	1.053	1.00
99_W	475_M	1.052	1.00
103_I	108_A	1.052	1.00
197_R	216_L	1.052	1.00
428_L	467_V	1.052	1.00
174_L	296_S	1.049	1.00
254_T	322_A	1.047	1.00
107_G	110_S	1.046	1.00
370_R	373_L	1.042	1.00
132_F	138_S	1.042	1.00
615_I	639_S	1.041	1.00
235_I	320_L	1.041	1.00
173_K	199_K	1.037	1.00
174_L	293_T	1.036	1.00
103_I	136_M	1.032	1.00
372_L	398_K	1.031	1.00
353_D	356_K	1.029	1.00
34_K	63_Y	1.029	1.00
375_T	401_Q	1.027	1.00
215_R	631_Q	1.022	1.00
75_T	80_Q	1.022	1.00
637_V	677_I	1.021	1.00
175_F	196_A	1.009	1.00
273_S	276_T	1.007	1.00
111_I	136_M	1.006	1.00
450_L	511_T	1.004	1.00
273_S	281_E	1.004	1.00
390_A	396_A	1.001	1.00
597_I	607_I	1.000	1.00
365_M	373_L	1.000	1.00
371_V	374_E	0.999	1.00
384_I	420_T	0.998	1.00
370_R	379_I	0.997	1.00
281_E	284_Y	0.994	1.00
298_I	321_P	0.993	1.00
232_A	316_T	0.991	1.00
272_V	276_T	0.990	1.00
206_I	221_I	0.987	1.00
260_L	323_I	0.984	1.00
225_P	636_V	0.982	1.00
491_R	508_D	0.981	1.00
202_K	218_D	0.978	1.00
102_L	407_D	0.977	1.00
597_I	602_A	0.976	1.00
238_I	287_A	0.970	1.00
260_L	264_V	0.970	1.00
285_R	288_K	0.970	1.00
369_G	372_L	0.970	1.00
596_F	631_Q	0.970	1.00
69_T	458_Y	0.968	1.00
364_N	368_L	0.968	1.00
255_V	535_K	0.966	1.00
383_F	471_L	0.965	1.00
615_I	675_V	0.965	1.00
563_H	676_Q	0.964	1.00
170_V	192_I	0.963	1.00
564_P	676_Q	0.959	1.00
437_T	450_L	0.959	1.00
397_N	401_Q	0.957	1.00
194_Q	197_R	0.957	1.00
560_D	674_R	0.956	1.00
62_I	455_I	0.955	1.00
206_I	286_L	0.955	1.00
204_V	289_M	0.953	1.00
595_L	677_I	0.952	1.00
290_Y	298_I	0.952	1.00
363_F	367_Q	0.951	1.00
224_K	633_L	0.950	1.00
598_N	632_V	0.947	1.00
363_F	371_V	0.947	1.00
68_L	427_V	0.946	1.00
38_V	59_T	0.944	1.00
29_H	37_K	0.944	1.00
519_K	523_P	0.942	1.00
25_G	41_D	0.942	1.00
491_R	494_L	0.940	1.00
390_A	400_R	0.938	1.00
206_I	223_I	0.938	1.00
563_H	617_N	0.936	1.00
322_A	536_I	0.936	1.00
229_S	313_I	0.936	1.00
76_G	80_Q	0.935	1.00
260_L	538_L	0.934	1.00
284_Y	288_K	0.932	1.00
88_W	467_V	0.930	1.00
430_A	467_V	0.929	1.00
431_T	457_R	0.929	1.00
233_L	267_Y	0.927	1.00
599_T	603_E	0.924	1.00
271_K	275_I	0.923	1.00
88_W	428_L	0.923	1.00
182_A	193_A	0.922	1.00
364_N	367_Q	0.920	1.00
237_H	264_V	0.918	1.00
268_D	272_V	0.918	1.00
95_I	471_L	0.916	1.00
295_P	329_H	0.915	1.00
434_F	454_V	0.913	1.00
491_R	495_D	0.913	1.00
296_S	326_Q	0.913	1.00
568_V	636_V	0.912	1.00
234_G	238_I	0.912	1.00
92_I	466_E	0.910	1.00
500_P	504_E	0.909	1.00
245_H	323_I	0.905	1.00
98_R	102_L	0.903	1.00
96_T	100_K	0.903	1.00
208_V	222_P	0.903	1.00
89_K	474_A	0.901	1.00
69_T	85_P	0.900	0.99
601_D	634_P	0.898	0.99
197_R	203_I	0.896	0.99
598_N	628_V	0.895	0.99
487_E	507_Y	0.894	0.99
109_E	362_S	0.894	0.99
364_N	373_L	0.893	0.99
83_F	427_V	0.891	0.99
565_F	677_I	0.887	0.99
481_E	484_D	0.886	0.99
269_P	284_Y	0.886	0.99
157_T	315_R	0.885	0.99
177_F	203_I	0.883	0.99
202_K	219_W	0.881	0.99
28_I	434_F	0.874	0.99
239_L	320_L	0.874	0.99
233_L	263_H	0.873	0.99
278_V	283_I	0.873	0.99
528_E	534_G	0.873	0.99
204_V	219_W	0.872	0.99
31_K	36_V	0.870	0.99
237_H	268_D	0.868	0.99
373_L	378_P	0.866	0.99
99_W	136_M	0.861	0.99
363_F	369_G	0.861	0.99
223_I	231_L	0.860	0.99
319_C	538_L	0.860	0.99
73_K	90_E	0.860	0.99
92_I	471_L	0.858	0.99
600_K	630_E	0.857	0.99
382_L	406_E	0.856	0.99
96_T	475_M	0.853	0.99
113_P	133_F	0.853	0.99
132_F	475_M	0.852	0.99
278_V	282_D	0.850	0.99
72_L	417_L	0.849	0.99
437_T	487_E	0.848	0.99
280_T	283_I	0.844	0.99
269_P	272_V	0.843	0.99
560_D	564_P	0.843	0.99
404_L	423_Y	0.842	0.99
421_A	427_V	0.842	0.99
13_K	43_D	0.841	0.99
109_E	139_S	0.841	0.99
176_I	298_I	0.841	0.99
295_P	332_G	0.840	0.99
258_E	262_E	0.836	0.99
487_E	511_T	0.836	0.99
507_Y	511_T	0.834	0.99
375_T	405_R	0.834	0.99
210_K	630_E	0.830	0.99
304_P	313_I	0.829	0.99
246_D	329_H	0.825	0.99
66_K	582_N	0.823	0.99
236_M	320_L	0.823	0.99
263_H	266_Q	0.821	0.99
269_P	273_S	0.820	0.99
366_N	370_R	0.819	0.99
282_D	289_M	0.818	0.99
71_P	87_S	0.816	0.99
12_F	454_V	0.815	0.99
462_K	467_V	0.814	0.99
619_R	673_G	0.814	0.99
210_K	222_P	0.812	0.99
26_L	51_I	0.811	0.99
174_L	202_K	0.811	0.99
597_I	613_V	0.810	0.99
418_T	421_A	0.809	0.99
238_I	280_T	0.807	0.99
281_E	285_R	0.806	0.99
622_C	656_L	0.805	0.99
183_V	213_T	0.804	0.99
520_R	523_P	0.804	0.99
99_W	383_F	0.804	0.99
374_E	406_E	0.803	0.99
437_T	486_D	0.802	0.99
618_S	674_R	0.801	0.99
602_A	607_I	0.801	0.99
70_T	87_S	0.800	0.99
156_Y	664_M	0.800	0.99
207_D	211_N	0.799	0.99
364_N	369_G	0.797	0.99
302_N	306_H	0.795	0.99
364_N	372_L	0.794	0.99
355_L	359_T	0.793	0.99
95_I	98_R	0.791	0.99
177_F	213_T	0.790	0.99
362_S	365_M	0.790	0.99
170_V	195_K	0.790	0.99
633_L	636_V	0.788	0.99
388_N	578_S	0.788	0.99
222_P	633_L	0.784	0.99
448_I	505_I	0.782	0.99
84_E	90_E	0.781	0.99
231_L	235_I	0.780	0.99
455_I	458_Y	0.779	0.99
233_L	264_V	0.778	0.99
624_L	653_V	0.777	0.99
560_D	563_H	0.777	0.99
372_L	376_D	0.777	0.99
94_T	97_S	0.776	0.99
230_A	234_G	0.776	0.99
232_A	320_L	0.775	0.98
62_I	432_S	0.769	0.98
532_P	537_E	0.768	0.98
298_I	317_I	0.767	0.98
390_A	403_L	0.767	0.98
364_N	374_E	0.765	0.98
288_K	291_G	0.762	0.98
593_P	643_W	0.760	0.98
356_K	359_T	0.758	0.98
224_K	277_G	0.758	0.98
289_M	293_T	0.758	0.98
156_Y	315_R	0.757	0.98
15_V	449_Q	0.756	0.98
88_W	462_K	0.756	0.98
364_N	371_V	0.756	0.98
579_T	582_N	0.755	0.98
132_F	468_F	0.754	0.98
69_T	72_L	0.753	0.98
669_T	672_S	0.753	0.98
40_G	49_G	0.753	0.98
242_E	291_G	0.753	0.98
99_W	103_I	0.752	0.98
374_E	377_P	0.751	0.98
380_R	406_E	0.749	0.98
174_L	290_Y	0.748	0.98
437_T	452_Q	0.748	0.98
28_I	454_V	0.746	0.98
86_I	91_A	0.744	0.98
97_S	100_K	0.743	0.98
100_K	475_M	0.742	0.98
241_K	269_P	0.741	0.98
16_C	24_C	0.740	0.98
12_F	28_I	0.739	0.98
501_H	504_E	0.738	0.98
223_I	276_T	0.738	0.98
63_Y	458_Y	0.737	0.98
365_M	370_R	0.735	0.98
510_L	513_H	0.734	0.98
31_K	34_K	0.733	0.98
381_S	426_I	0.732	0.98
469_R	473_E	0.730	0.98
607_I	628_V	0.730	0.98
234_G	269_P	0.729	0.98
397_N	655_A	0.729	0.98
366_N	666_G	0.729	0.98
602_A	629_G	0.727	0.98
447_Y	517_K	0.727	0.98
214_G	220_F	0.726	0.98
363_F	368_L	0.725	0.98
48_A	195_K	0.725	0.98
559_T	619_R	0.724	0.98
269_P	280_T	0.723	0.98
555_T	559_T	0.722	0.98
529_L	533_S	0.721	0.98
229_S	316_T	0.721	0.98
92_I	96_T	0.720	0.98
537_E	540_S	0.720	0.98
234_G	271_K	0.718	0.98
270_E	273_S	0.718	0.98
92_I	467_V	0.717	0.98
367_Q	370_R	0.717	0.98
500_P	503_A	0.717	0.98
465_T	489_L	0.717	0.98
619_R	657_T	0.716	0.97
414_D	427_V	0.716	0.97
74_R	81_A	0.715	0.97
600_K	604_K	0.715	0.97
363_F	370_R	0.715	0.97
22_D	188_H	0.714	0.97
234_G	268_D	0.713	0.97
123_L	126_E	0.713	0.97
76_G	82_I	0.712	0.97
20_C	24_C	0.711	0.97
308_D	669_T	0.711	0.97
466_E	469_R	0.710	0.97
64_D	416_F	0.710	0.97
33_G	456_E	0.710	0.97
367_Q	371_V	0.709	0.97
615_I	624_L	0.709	0.97
355_L	358_R	0.708	0.97
597_I	628_V	0.706	0.97
153_G	318_A	0.704	0.97
419_E	644_A	0.703	0.97
432_S	458_Y	0.702	0.97
519_K	522_K	0.702	0.97
622_C	655_A	0.702	0.97
390_A	423_Y	0.702	0.97
40_G	51_I	0.700	0.97
263_H	267_Y	0.699	0.97
273_S	278_V	0.698	0.97
92_I	95_I	0.697	0.97
124_T	127_G	0.696	0.97
529_L	536_I	0.696	0.97
384_I	412_V	0.694	0.97
295_P	330_T	0.692	0.97
187_M	191_T	0.691	0.97
102_L	380_R	0.691	0.97
98_R	381_S	0.690	0.97
388_N	420_T	0.690	0.97
661_L	666_G	0.689	0.97
287_A	291_G	0.687	0.97
487_E	494_L	0.687	0.97
414_D	418_T	0.686	0.97
355_L	360_P	0.685	0.97
154_Y	318_A	0.684	0.97
521_E	524_L	0.683	0.97
123_L	130_R	0.683	0.97
166_P	517_K	0.682	0.97
135_R	477_F	0.682	0.97
363_F	366_N	0.681	0.97
184_S	212_Q	0.681	0.97
16_C	20_C	0.680	0.97
157_T	539_Y	0.679	0.97
473_E	484_D	0.679	0.97
507_Y	510_L	0.678	0.97
115_S	141_L	0.676	0.96
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168_E	331_G	0.675	0.96
112_L	382_L	0.675	0.96
253_Y	527_G	0.674	0.96
210_K	220_F	0.673	0.96
567_Y	639_S	0.671	0.96
131_R	134_Y	0.671	0.96
364_N	370_R	0.671	0.96
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221_I	231_L	0.669	0.96
109_E	138_S	0.668	0.96
239_L	243_N	0.667	0.96
229_S	309_N	0.664	0.96
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396_A	652_L	0.663	0.96
106_E	110_S	0.663	0.96
202_K	292_E	0.662	0.96
492_Q	496_H	0.662	0.96
181_N	184_S	0.661	0.96
526_P	529_L	0.660	0.96
431_T	436_N	0.659	0.96
95_I	383_F	0.658	0.96
397_N	400_R	0.658	0.96
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63_Y	455_I	0.656	0.96
158_M	318_A	0.656	0.96
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157_T	318_A	0.653	0.96
657_T	673_G	0.653	0.96
290_Y	320_L	0.650	0.96
368_L	372_L	0.650	0.96
584_E	588_K	0.650	0.96
353_D	357_G	0.649	0.96
44_H	47_T	0.647	0.95
233_L	316_T	0.644	0.95
209_H	596_F	0.644	0.95
603_E	608_V	0.643	0.95
565_F	635_G	0.641	0.95
368_L	374_E	0.641	0.95
286_L	289_M	0.639	0.95
173_K	296_S	0.639	0.95
312_M	315_R	0.638	0.95
123_L	127_G	0.638	0.95
403_L	423_Y	0.638	0.95
210_K	214_G	0.637	0.95
231_L	278_V	0.637	0.95
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361_R	365_M	0.635	0.95
152_E	311_G	0.634	0.95
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202_K	285_R	0.633	0.95
373_L	376_D	0.633	0.95
93_D	96_T	0.632	0.95
102_L	106_E	0.632	0.95
113_P	132_F	0.632	0.95
598_N	633_L	0.632	0.95
153_G	157_T	0.632	0.95
392_V	578_S	0.631	0.95
187_M	190_I	0.630	0.95
240_F	323_I	0.629	0.95
89_K	93_D	0.627	0.95
75_T	83_F	0.627	0.95
178_W	317_I	0.626	0.95
260_L	263_H	0.625	0.95
120_M	385_Y	0.624	0.95
368_L	373_L	0.624	0.95
127_G	131_R	0.621	0.94
368_L	371_V	0.621	0.94
287_A	320_L	0.621	0.94
75_T	81_A	0.616	0.94
572_N	594_K	0.614	0.94
632_V	638_V	0.614	0.94
172_T	295_P	0.613	0.94
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300_I	334_A	0.612	0.94
16_C	55_V	0.612	0.94
60_E	584_E	0.612	0.94
195_K	199_K	0.612	0.94
249_F	254_T	0.611	0.94
516_M	520_R	0.611	0.94
367_Q	373_L	0.610	0.94
130_R	134_Y	0.610	0.94
172_T	297_F	0.610	0.94
508_D	511_T	0.609	0.94
321_P	334_A	0.609	0.94
132_F	136_M	0.608	0.94
129_D	133_F	0.608	0.94
354_L	357_G	0.608	0.94
658_P	673_G	0.608	0.94
24_C	52_C	0.608	0.94
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89_K	470_L	0.607	0.94
184_S	209_H	0.606	0.94
556_P	559_T	0.606	0.94
423_Y	427_V	0.606	0.94
33_G	36_V	0.605	0.94
209_H	638_V	0.604	0.94
354_L	496_H	0.603	0.93
169_T	299_R	0.603	0.93
384_I	389_P	0.602	0.93
105_E	407_D	0.602	0.93
607_I	611_A	0.602	0.93
196_A	199_K	0.602	0.93
236_M	319_C	0.600	0.93
290_Y	321_P	0.598	0.93
222_P	225_P	0.598	0.93
94_T	381_S	0.597	0.93
505_I	510_L	0.597	0.93
382_L	410_T	0.596	0.93
315_R	539_Y	0.595	0.93
239_L	323_I	0.595	0.93
619_R	674_R	0.594	0.93
398_K	659_D	0.593	0.93
171_H	295_P	0.593	0.93
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101_Q	407_D	0.592	0.93
362_S	371_V	0.592	0.93
513_H	516_M	0.591	0.93
304_P	314_V	0.590	0.93
490_I	493_A	0.590	0.93
129_D	468_F	0.590	0.93
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365_M	374_E	0.589	0.93
30_K	455_I	0.588	0.93
30_K	35_I	0.588	0.93
563_H	618_S	0.587	0.93
50_N	191_T	0.587	0.93
294_S	329_H	0.586	0.92
585_K	588_K	0.586	0.92
615_I	677_I	0.585	0.92
662_S	665_G	0.584	0.92
81_A	84_E	0.584	0.92
583_N	586_H	0.584	0.92
14_S	26_L	0.582	0.92
599_T	629_G	0.581	0.92
619_R	658_P	0.581	0.92
237_H	272_V	0.581	0.92
184_S	573_H	0.581	0.92
516_M	519_K	0.581	0.92
322_A	538_L	0.580	0.92
53_N	573_H	0.580	0.92
89_K	462_K	0.580	0.92
483_K	489_L	0.580	0.92
44_H	449_Q	0.579	0.92
346_T	349_L	0.578	0.92
130_R	133_F	0.578	0.92
261_R	264_V	0.578	0.92
435_E	458_Y	0.578	0.92
365_M	372_L	0.577	0.92
311_G	664_M	0.577	0.92
594_K	640_Q	0.577	0.92
222_P	282_D	0.577	0.92
133_F	138_S	0.577	0.92
432_S	455_I	0.576	0.92
176_I	296_S	0.576	0.92
147_S	151_S	0.576	0.92
227_T	230_A	0.576	0.92
58_M	433_A	0.575	0.92
488_V	511_T	0.575	0.92
531_T	535_K	0.574	0.92
158_M	334_A	0.574	0.92
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12_F	452_Q	0.571	0.91
584_E	587_I	0.570	0.91
463_S	486_D	0.570	0.91
35_I	59_T	0.570	0.91
157_T	319_C	0.569	0.91
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83_F	86_I	0.569	0.91
249_F	253_Y	0.569	0.91
241_K	261_R	0.569	0.91
557_L	619_R	0.568	0.91
522_K	525_F	0.568	0.91
72_L	83_F	0.568	0.91
337_H	340_G	0.568	0.91
575_F	580_F	0.567	0.91
230_A	271_K	0.566	0.91
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246_D	249_F	0.566	0.91
230_A	272_V	0.565	0.91
311_G	662_S	0.564	0.91
64_D	582_N	0.564	0.91
566_M	672_S	0.564	0.91
70_T	86_I	0.563	0.91
346_T	351_R	0.563	0.91
493_A	496_H	0.563	0.91
281_E	288_K	0.563	0.91
533_S	536_I	0.562	0.91
400_R	423_Y	0.561	0.91
106_E	407_D	0.561	0.91
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533_S	540_S	0.559	0.91
126_E	131_R	0.559	0.91
313_I	317_I	0.559	0.91
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237_H	266_Q	0.558	0.91
283_I	287_A	0.558	0.91
383_F	411_V	0.557	0.90
593_P	640_Q	0.557	0.90
171_H	331_G	0.557	0.90
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536_I	543_M	0.554	0.90
257_Y	538_L	0.554	0.90
572_N	590_E	0.554	0.90
311_G	665_G	0.553	0.90
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598_N	601_D	0.553	0.90
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165_D	168_E	0.548	0.90
123_L	133_F	0.548	0.90
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539_Y	544_K	0.548	0.90
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419_E	422_A	0.547	0.90
348_A	352_P	0.546	0.90
361_R	368_L	0.545	0.90
612_P	626_A	0.545	0.90
412_V	420_T	0.544	0.89
601_D	628_V	0.543	0.89
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245_H	261_R	0.542	0.89
182_A	213_T	0.541	0.89
396_A	400_R	0.541	0.89
234_G	273_S	0.540	0.89
605_H	637_V	0.540	0.89
366_N	372_L	0.540	0.89
526_P	531_T	0.539	0.89
295_P	326_Q	0.538	0.89
362_S	367_Q	0.538	0.89
107_G	380_R	0.538	0.89
342_L	345_N	0.537	0.89
361_R	366_N	0.537	0.89
571_P	641_G	0.536	0.89
579_T	583_N	0.536	0.89
628_V	631_Q	0.536	0.89
412_V	418_T	0.536	0.89
487_E	490_I	0.536	0.89
308_D	663_D	0.535	0.89
415_L	430_A	0.534	0.89
536_I	539_Y	0.534	0.89
457_R	461_S	0.534	0.89
598_N	605_H	0.534	0.89
76_G	84_E	0.533	0.88
208_V	568_V	0.533	0.88
384_I	403_L	0.531	0.88
163_G	166_P	0.531	0.88
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383_F	468_F	0.531	0.88
30_K	454_V	0.530	0.88
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225_P	568_V	0.530	0.88
282_D	286_L	0.530	0.88
382_L	403_L	0.530	0.88
237_H	271_K	0.529	0.88
340_G	343_E	0.529	0.88
41_D	44_H	0.528	0.88
194_Q	216_L	0.528	0.88
530_P	534_G	0.528	0.88
491_R	507_Y	0.527	0.88
254_T	257_Y	0.527	0.88
147_S	150_G	0.527	0.88
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62_I	434_F	0.526	0.88
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38_V	58_M	0.526	0.88
381_S	406_E	0.525	0.88
180_I	301_G	0.525	0.88
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123_L	129_D	0.523	0.88
345_N	350_Q	0.523	0.88
178_W	320_L	0.523	0.88
555_T	558_V	0.522	0.87
594_K	625_T	0.522	0.87
370_R	377_P	0.522	0.87
399_V	403_L	0.522	0.87
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209_H	570_G	0.521	0.87
207_D	214_G	0.520	0.87
345_N	348_A	0.519	0.87
472_A	476_G	0.519	0.87
136_M	475_M	0.519	0.87
148_K	667_G	0.519	0.87
345_N	349_L	0.518	0.87
621_E	678_E	0.518	0.87
567_Y	653_V	0.518	0.87
369_G	374_E	0.517	0.87
519_K	524_L	0.516	0.87
536_I	540_S	0.516	0.87
410_T	424_A	0.516	0.87
207_D	220_F	0.515	0.87
534_G	540_S	0.514	0.87
540_S	543_M	0.514	0.87
366_N	371_V	0.514	0.87
367_Q	374_E	0.514	0.87
132_F	471_L	0.513	0.87
149_A	667_G	0.513	0.87
535_K	541_E	0.513	0.87
411_V	426_I	0.513	0.87
68_L	417_L	0.512	0.86
362_S	372_L	0.512	0.86
176_I	290_Y	0.511	0.86
127_G	130_R	0.511	0.86
242_E	269_P	0.511	0.86
188_H	191_T	0.510	0.86
39_Q	42_P	0.510	0.86
567_Y	637_V	0.510	0.86
365_M	369_G	0.509	0.86
601_D	605_H	0.509	0.86
564_P	605_H	0.509	0.86
366_N	373_L	0.509	0.86
224_K	566_M	0.509	0.86
387_T	393_A	0.508	0.86
531_T	534_G	0.508	0.86
191_T	195_K	0.508	0.86
534_G	538_L	0.508	0.86
308_D	660_R	0.508	0.86
144_T	148_K	0.508	0.86
126_E	130_R	0.508	0.86
101_Q	104_D	0.508	0.86
193_A	203_I	0.508	0.86
257_Y	260_L	0.507	0.86
169_T	193_A	0.507	0.86
127_G	133_F	0.506	0.86
132_F	472_A	0.506	0.86
559_T	674_R	0.506	0.86
43_D	48_A	0.506	0.86
310_G	314_V	0.505	0.86
172_T	296_S	0.505	0.86
80_Q	84_E	0.504	0.86
103_I	110_S	0.503	0.85
361_R	369_G	0.502	0.85
24_C	55_V	0.502	0.85
180_I	299_R	0.502	0.85
611_A	626_A	0.501	0.85
365_M	368_L	0.501	0.85
617_N	673_G	0.501	0.85
52_C	55_V	0.500	0.85
30_K	33_G	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2e7zA	1	0.9632	100	0.173	Contact Map
2vpzA	1	0.9779	100	0.176	Contact Map
1h0hA	1	0.9838	100	0.178	Contact Map
2iv2X	1	0.9235	100	0.187	Contact Map
2ivfA	1	0.9868	100	0.191	Contact Map
1kqfA	3	0.9853	100	0.193	Contact Map
2napA	1	0.9618	100	0.199	Contact Map
1q16A	2	0.9941	100	0.199	Contact Map
3ml1A	1	0.9706	100	0.204	Contact Map
1ti6A	3	0.9794	100	0.227	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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