GREMLIN Database
S5AEB - Stage V sporulation protein AEB
UniProt: C0H450 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 116 (114)
Sequences: 588 (302)
Seq/√Len: 28.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
43_D68_H5.0671.00
49_D53_E3.6861.00
19_L23_I3.4861.00
43_D72_H3.3551.00
69_S94_T3.2431.00
13_I35_F2.9911.00
5_L8_V2.9311.00
94_T98_I2.7621.00
5_L54_F2.5850.99
100_A104_F2.3290.99
74_A86_I2.2810.98
88_M96_A2.1900.98
76_H80_I2.1680.98
8_V12_A2.0040.97
77_Q92_E1.9440.96
17_G35_F1.7400.92
49_D68_H1.7380.92
48_Y59_A1.7050.92
16_V38_I1.6550.90
19_L111_I1.6060.89
6_A56_G1.5780.88
21_L31_V1.5100.86
26_L34_S1.4900.85
68_H72_H1.4670.84
9_C13_I1.4490.83
44_G71_L1.4240.82
40_A71_L1.3640.79
9_C55_A1.3640.79
99_S103_L1.3140.77
24_F31_V1.3080.76
86_I103_L1.3030.76
73_G93_L1.2990.76
9_C54_F1.2820.75
19_L24_F1.2630.74
85_G97_G1.2620.74
83_F86_I1.2530.73
74_A78_A1.2190.71
105_A110_V1.1860.69
29_A34_S1.1450.66
83_F96_A1.1080.64
90_I95_S1.0940.63
38_I41_I1.0800.62
6_A114_P1.0770.61
65_S90_I1.0650.60
20_L23_I1.0600.60
45_F50_K1.0480.59
24_F30_H1.0460.59
65_S93_L1.0320.58
15_I91_F1.0190.57
17_G64_V1.0100.56
8_V15_I0.9980.55
49_D72_H0.9760.54
77_Q80_I0.9680.53
73_G89_G0.9570.52
4_L8_V0.9530.52
77_Q93_L0.9400.51
30_H63_I0.9380.51
52_I60_T0.9250.50
25_K47_I0.8990.48
64_V113_K0.8950.47
25_K91_F0.8950.47
43_D69_S0.8830.47
81_H88_M0.8800.46
37_V75_M0.8790.46
109_A114_P0.8630.45
2_D5_L0.8490.44
33_T106_F0.8380.43
47_I50_K0.8320.43
44_G106_F0.8280.42
37_V105_A0.8180.42
98_I101_A0.8150.41
21_L29_A0.8040.41
20_L32_M0.8020.40
44_G50_K0.7970.40
20_L104_F0.7920.40
97_G101_A0.7870.39
38_I42_L0.7850.39
88_M92_E0.7840.39
3_Y23_I0.7770.39
71_L86_I0.7660.38
3_Y76_H0.7640.38
38_I45_F0.7630.38
50_K103_L0.7440.36
78_A83_F0.7400.36
20_L29_A0.7360.36
99_S102_I0.7310.35
75_M79_H0.7260.35
10_G32_M0.7190.34
84_I110_V0.7170.34
37_V106_F0.7150.34
105_A113_K0.7140.34
24_F34_S0.7130.34
35_F103_L0.7090.34
17_G27_T0.7080.34
111_I114_P0.7080.34
5_L9_C0.7080.34
64_V68_H0.7000.33
33_T75_M0.6960.33
34_S41_I0.6950.33
35_F99_S0.6900.32
89_G97_G0.6900.32
12_A19_L0.6780.32
32_M90_I0.6740.31
42_L83_F0.6720.31
52_I68_H0.6710.31
65_S68_H0.6700.31
20_L64_V0.6690.31
20_L26_L0.6680.31
50_K53_E0.6670.31
101_A112_F0.6660.31
24_F33_T0.6640.31
87_G96_A0.6630.31
20_L34_S0.6620.31
20_L24_F0.6610.30
42_L47_I0.6590.30
3_Y113_K0.6560.30
10_G62_P0.6510.30
12_A15_I0.6500.30
101_A105_A0.6460.30
87_G100_A0.6330.29
33_T65_S0.6300.28
77_Q81_H0.6300.28
47_I51_F0.6280.28
107_I115_K0.6280.28
26_L30_H0.6270.28
75_M83_F0.6270.28
32_M44_G0.6260.28
55_A108_V0.6250.28
94_T108_V0.6190.28
51_F94_T0.6180.28
106_F114_P0.6100.27
62_P89_G0.6070.27
51_F55_A0.6060.27
22_D36_V0.6040.27
68_H94_T0.5990.27
26_L48_Y0.5980.27
63_I102_I0.5930.26
15_I35_F0.5820.26
31_V44_G0.5810.26
72_H87_G0.5770.25
65_S95_S0.5760.25
74_A94_T0.5760.25
83_F112_F0.5760.25
32_M65_S0.5740.25
12_A41_I0.5690.25
13_I55_A0.5670.25
6_A55_A0.5660.25
57_G109_A0.5640.25
91_F106_F0.5610.24
46_G60_T0.5570.24
33_T90_I0.5520.24
96_A99_S0.5510.24
24_F85_G0.5390.23
68_H103_L0.5380.23
9_C51_F0.5330.23
8_V16_V0.5290.23
41_I84_I0.5260.22
52_I81_H0.5200.22
46_G73_G0.5200.22
46_G84_I0.5200.22
15_I29_A0.5190.22
24_F29_A0.5150.22
73_G91_F0.5140.22
15_I64_V0.5140.22
35_F108_V0.5130.22
90_I93_L0.5100.22
43_D71_L0.5080.21
81_H114_P0.5040.21
106_F110_V0.5020.21
91_F102_I0.5010.21
43_D63_I0.5000.21
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1jb0K 1 0.3362 42.9 0.928 Contact Map
4xk8K 1 0.3103 26.4 0.935 Contact Map
4kt0K 1 0.3793 12 0.945 Contact Map
3lynA 2 0.319 4.8 0.954 Contact Map
2lisA 1 0.319 4.7 0.954 Contact Map
3qnqA 2 0.9741 2.5 0.96 Contact Map
4f50A 1 0.6379 2 0.962 Contact Map
2wscK 1 0.5172 2 0.962 Contact Map
4hzuS 1 0.6983 1.5 0.965 Contact Map
2i68A 2 0.6034 1.4 0.965 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0054 seconds.