GREMLIN Database
YPZJ - Uncharacterized protein YpzJ
UniProt: C0H447 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 68 (65)
Sequences: 176 (107)
Seq/√Len: 13.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_A24_T3.5960.99
39_V48_S2.4920.91
20_A25_G2.2980.87
17_K35_N2.2930.87
55_S60_N2.0850.81
10_G13_E1.6680.64
56_S60_N1.6520.64
19_I50_F1.6460.63
36_R64_L1.5750.60
15_G43_K1.5350.58
15_G52_N1.5180.57
21_T50_F1.5170.57
11_S62_L1.4780.55
7_I41_Y1.4240.52
24_T35_N1.4200.52
41_Y44_N1.4060.51
5_G65_F1.2870.45
4_K48_S1.2800.44
7_I56_S1.2530.43
10_G61_I1.2510.43
16_Q40_V1.1480.38
44_N61_I1.1470.38
31_D34_H1.1440.37
55_S64_L1.1350.37
32_V44_N1.1330.37
27_S34_H1.1330.37
28_K33_Q1.1300.37
38_L55_S1.1020.35
18_E27_S1.0930.35
16_Q38_L1.0890.35
4_K39_V1.0760.34
17_K20_A1.0590.33
12_T57_T1.0490.33
3_N46_G1.0350.32
4_K54_E1.0270.32
40_V47_Y0.9970.30
16_Q37_F0.9970.30
40_V59_G0.9940.30
10_G46_G0.9880.30
28_K39_V0.9830.30
32_V62_L0.9770.30
3_N50_F0.9620.29
10_G57_T0.9530.29
28_K31_D0.9460.28
17_K34_H0.9200.27
39_V50_F0.8960.26
25_G59_G0.8770.25
22_T33_Q0.8660.25
43_K54_E0.8610.25
46_G58_A0.8560.25
27_S66_F0.8550.25
21_T52_N0.8440.24
14_A66_F0.8370.24
19_I39_V0.8300.24
60_N65_F0.8260.23
7_I47_Y0.8250.23
34_H53_K0.8190.23
15_G47_Y0.8170.23
33_Q60_N0.8150.23
14_A61_I0.8090.23
14_A35_N0.7950.22
32_V64_L0.7920.22
3_N58_A0.7920.22
24_T51_Y0.7910.22
41_Y46_G0.7650.21
29_L54_E0.7630.21
19_I35_N0.7250.20
17_K52_N0.7180.20
54_E57_T0.7150.19
4_K14_A0.6890.19
17_K41_Y0.6770.18
38_L59_G0.6700.18
7_I52_N0.6640.18
36_R48_S0.6610.18
4_K58_A0.6500.17
38_L62_L0.6500.17
18_E38_L0.6440.17
5_G48_S0.6360.17
3_N38_L0.6360.17
13_E19_I0.6300.17
53_K60_N0.6290.17
38_L41_Y0.6250.17
12_T43_K0.6220.17
29_L66_F0.6170.16
19_I48_S0.6120.16
24_T34_H0.6040.16
5_G51_Y0.5990.16
26_L29_L0.5930.16
20_A29_L0.5880.16
5_G56_S0.5830.15
47_Y65_F0.5760.15
5_G67_G0.5700.15
30_F57_T0.5690.15
48_S65_F0.5600.15
4_K61_I0.5290.14
36_R53_K0.5220.14
14_A52_N0.5150.14
36_R62_L0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2k4xA 1 0.5882 96.1 0.807 Contact Map
4bpe9 1 0.6618 87 0.857 Contact Map
3po3S 1 0.6471 86.2 0.858 Contact Map
1pqvS 1 0.6471 85.4 0.86 Contact Map
3j3af 1 0.5147 83.5 0.863 Contact Map
4ujpg 1 0.5147 83.4 0.863 Contact Map
4uer9 1 0.5147 82.6 0.864 Contact Map
4cuyf 1 0.5147 82.5 0.865 Contact Map
3zey9 1 0.4853 82.2 0.865 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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