GREMLIN Database
YBZH - Uncharacterized HTH-type transcriptional regulator YbzH
UniProt: C0H3S9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 100 (93)
Sequences: 579 (368)
Seq/√Len: 38.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_E27_R4.7561.00
21_W50_K2.8731.00
69_G85_D2.5971.00
72_K83_K2.3791.00
93_A96_L2.3671.00
4_I16_L2.2040.99
53_M58_A2.1050.99
86_E89_I2.0890.99
73_A80_T2.0340.99
75_R80_T2.0310.99
44_V61_Y1.9990.99
9_A68_A1.9040.98
56_S63_T1.8360.98
62_L81_Y1.7620.97
9_A64_I1.7140.96
62_L71_I1.6800.96
85_D88_A1.6260.95
18_I47_I1.5530.94
40_I74_E1.5270.93
72_K85_D1.4580.92
7_F95_F1.4550.91
43_C79_Y1.3860.89
65_L71_I1.3720.89
7_F16_L1.3590.88
6_V88_A1.3550.88
89_I93_A1.3480.88
24_E28_H1.3450.88
88_A91_K1.3380.88
56_S77_G1.3350.87
31_P46_Q1.3080.86
51_L58_A1.2390.83
32_H37_M1.2390.83
30_A46_Q1.1950.81
54_T57_T1.1940.81
7_F96_L1.1890.81
12_N61_Y1.1350.77
23_K86_E1.1140.76
69_G72_K1.1030.75
5_E67_R1.0920.75
11_S61_Y1.0620.72
6_V92_L1.0570.72
90_G94_D1.0380.71
91_K95_F1.0220.70
28_H51_L0.9930.67
37_M54_T0.9890.67
59_S77_G0.9780.66
12_N75_R0.9710.65
40_I76_I0.9620.65
6_V70_L0.9610.65
7_F92_L0.9550.64
54_T78_K0.9440.63
4_I13_E0.9400.63
61_Y80_T0.9350.63
44_V75_R0.9230.62
25_P62_L0.9200.61
61_Y75_R0.9170.61
37_M40_I0.9040.60
44_V82_Y0.9030.60
32_H74_E0.9000.60
56_S59_S0.8990.59
6_V12_N0.8920.59
12_N47_I0.8830.58
56_S66_L0.8780.58
17_Q21_W0.8670.57
5_E96_L0.8610.56
88_A95_F0.8560.56
6_V95_F0.8540.56
44_V80_T0.8300.53
57_T63_T0.8240.53
9_A92_L0.8180.52
45_S66_L0.8030.51
21_W51_L0.8010.51
36_D46_Q0.8000.51
29_F32_H0.7800.49
88_A92_L0.7770.49
23_K33_E0.7700.48
16_L92_L0.7540.47
44_V62_L0.7520.46
18_I22_L0.7470.46
32_H36_D0.7450.46
31_P76_I0.7420.46
84_R89_I0.7310.45
55_Q79_Y0.7250.44
59_S80_T0.7250.44
23_K84_R0.7220.44
11_S69_G0.7190.43
13_E16_L0.7120.43
85_D89_I0.7110.43
19_L37_M0.7100.43
17_Q62_L0.7080.43
24_E30_A0.7060.42
18_I42_V0.7030.42
9_A65_L0.6970.42
94_D97_K0.6960.41
14_S17_Q0.6870.41
41_G74_E0.6860.41
75_R82_Y0.6800.40
48_T65_L0.6750.40
60_Q89_I0.6710.39
33_E53_M0.6660.39
36_D42_V0.6610.38
38_N65_L0.6560.38
57_T83_K0.6510.38
49_D75_R0.6470.37
38_N52_K0.6460.37
30_A57_T0.6310.36
74_E78_K0.6100.34
47_I50_K0.6090.34
30_A50_K0.6070.34
20_Q91_K0.6050.34
8_K85_D0.6010.34
8_K25_P0.5870.32
12_N44_V0.5820.32
45_S60_Q0.5810.32
56_S70_L0.5810.32
71_I85_D0.5770.32
52_K92_L0.5770.32
29_F50_K0.5720.31
68_A88_A0.5710.31
39_T74_E0.5710.31
57_T67_R0.5670.31
34_G37_M0.5600.30
87_E91_K0.5580.30
44_V48_T0.5560.30
63_T67_R0.5540.30
17_Q50_K0.5540.30
28_H60_Q0.5530.30
23_K97_K0.5470.29
29_F42_V0.5470.29
33_E38_N0.5450.29
60_Q64_I0.5420.29
8_K79_Y0.5370.29
12_N81_Y0.5330.28
68_A90_G0.5300.28
38_N74_E0.5170.27
22_L42_V0.5160.27
26_D38_N0.5150.27
5_E16_L0.5090.27
46_Q73_A0.5070.26
24_E87_E0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2vxzA 1 0.79 99.6 0.639 Contact Map
1r1tA 2 0.85 99.5 0.677 Contact Map
1u2wA 2 0.86 99.4 0.69 Contact Map
2kkoA 2 0.85 99.3 0.697 Contact Map
1q1hA 1 0.77 99.3 0.699 Contact Map
2jscA 2 0.84 99.3 0.701 Contact Map
1r1uA 2 0.85 99.3 0.702 Contact Map
3pqkA 2 0.85 99.3 0.709 Contact Map
4k2eA 2 0.85 99.3 0.709 Contact Map
2zkzA 2 0.84 99.2 0.713 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0051 seconds.