GREMLIN Database
YWZG - Putative DNA-binding protein YwzG
UniProt: C0H3S6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 112 (101)
Sequences: 3189 (2128)
Seq/√Len: 211.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
23_P64_Y3.7711.00
98_S102_D3.4361.00
60_Y86_V2.7911.00
62_S78_R2.7781.00
20_N84_K2.6291.00
25_Y76_Y2.2361.00
59_G82_E2.1781.00
23_P78_R2.0101.00
12_V54_K1.9401.00
86_V89_E1.8681.00
18_L24_M1.8511.00
14_L101_M1.8291.00
64_Y78_R1.8231.00
79_I84_K1.7471.00
15_V51_S1.7311.00
32_E35_S1.7251.00
19_L24_M1.7181.00
65_W73_D1.6491.00
14_L104_I1.6421.00
22_R32_E1.6301.00
81_D84_K1.6211.00
22_R28_E1.6031.00
34_G42_Q1.5851.00
24_M32_E1.5721.00
13_I90_R1.5411.00
46_G50_P1.4971.00
26_G52_L1.4881.00
23_P66_E1.4651.00
17_T105_L1.4411.00
91_T105_L1.4141.00
24_M28_E1.3971.00
82_E85_E1.3871.00
5_E8_K1.3631.00
32_E36_R1.3191.00
13_I105_L1.3161.00
28_E32_E1.2941.00
20_N87_L1.2441.00
14_L33_M1.2361.00
17_T91_T1.2171.00
88_A92_K1.1911.00
12_V51_S1.1481.00
85_E89_E1.1371.00
55_L60_Y1.1311.00
56_E61_I1.1051.00
56_E63_S1.1011.00
88_A91_T1.0761.00
25_Y28_E1.0671.00
60_Y82_E1.0651.00
95_S106_K1.0561.00
24_M29_L1.0541.00
11_T43_M1.0511.00
19_L61_I1.0421.00
87_L91_T1.0381.00
20_N91_T1.0221.00
90_R93_E0.9851.00
62_S80_T0.9711.00
84_K88_A0.9641.00
99_A103_R0.9631.00
33_M43_M0.9430.99
31_K34_G0.8890.99
67_K73_D0.8820.99
95_S102_D0.8650.99
68_Q72_P0.8610.99
91_T95_S0.8550.99
92_K96_V0.8520.99
96_V99_A0.8510.99
95_S98_S0.8480.99
86_V90_R0.8470.99
53_H61_I0.8440.99
12_V58_Q0.8410.99
30_V48_L0.8370.99
94_W101_M0.8280.99
17_T87_L0.8260.99
67_K72_P0.8240.99
85_E88_A0.8160.99
51_S90_R0.7920.98
21_E36_R0.7880.98
17_T20_N0.7770.98
34_G39_N0.7690.98
35_S106_K0.7650.98
95_S99_A0.7620.98
26_G77_Y0.7500.97
66_E69_E0.7480.97
30_V44_K0.7350.97
94_W98_S0.7330.97
40_E100_M0.7260.97
85_E99_A0.7260.97
7_V90_R0.7230.97
82_E86_V0.7160.97
10_S101_M0.7150.97
99_A106_K0.7130.97
71_G74_R0.7090.96
40_E96_V0.6850.96
64_Y76_Y0.6800.95
97_F105_L0.6650.95
81_D85_E0.6610.95
94_W102_D0.6610.95
53_H57_R0.6570.95
46_G53_H0.6560.94
21_E32_E0.6540.94
50_P75_K0.6520.94
21_E35_S0.6510.94
85_E92_K0.6480.94
92_K106_K0.6460.94
6_L10_S0.6330.93
58_Q86_V0.6300.93
31_K45_E0.6210.93
65_W79_I0.6210.93
68_Q73_D0.6170.92
17_T21_E0.6120.92
13_I43_M0.6110.92
35_S89_E0.6070.92
59_G99_A0.5990.91
6_L97_F0.5990.91
21_E106_K0.5970.91
41_L75_K0.5930.91
30_V52_L0.5920.91
15_V29_L0.5920.91
61_I77_Y0.5800.90
7_V41_L0.5740.90
46_G75_K0.5730.89
5_E65_W0.5710.89
9_G47_T0.5670.89
101_M105_L0.5650.89
65_W75_K0.5630.89
12_V55_L0.5620.89
45_E77_Y0.5610.88
26_G63_S0.5560.88
11_T52_L0.5510.88
44_K48_L0.5490.87
91_T106_K0.5480.87
35_S85_E0.5480.87
18_L22_R0.5420.87
39_N42_Q0.5390.86
17_T70_K0.5370.86
89_E92_K0.5320.86
30_V46_G0.5320.86
11_T46_G0.5300.86
18_L32_E0.5240.85
92_K103_R0.5220.85
92_K95_S0.5210.85
25_Y47_T0.5200.84
6_L104_I0.5190.84
89_E93_E0.5150.84
53_H90_R0.5110.83
14_L97_F0.5090.83
10_S15_V0.5090.83
100_M104_I0.5080.83
68_Q74_R0.5080.83
99_A104_I0.5050.83
40_E99_A0.5040.83
89_E95_S0.5000.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1bm9A 2 0.9375 99.9 0.329 Contact Map
1xmaA 2 0.9286 99.8 0.484 Contact Map
2zfwA 2 0.8839 99.8 0.492 Contact Map
2rkhA 2 0.8571 99.8 0.494 Contact Map
2e1nA 2 0.8839 99.8 0.506 Contact Map
3l9fA 2 0.9018 99.7 0.528 Contact Map
2dqlA 2 0.9107 99.7 0.528 Contact Map
3f8bA 2 0.9375 99.7 0.532 Contact Map
3hhhA 2 0.9286 99.7 0.543 Contact Map
2eshA 2 0.9375 99.7 0.56 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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