GREMLIN Database
YTRH - Sporulation membrane protein YtrH
UniProt: C0H3P8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 113 (103)
Sequences: 175 (122)
Seq/√Len: 12.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
15_Y98_S3.6570.99
25_G51_L2.6510.92
65_D105_W2.4100.87
75_L82_I2.3710.86
47_L51_L2.2520.83
93_M99_G2.1910.81
72_R82_I2.1310.79
34_Y68_Y1.9030.71
19_L97_Q1.7810.65
35_L38_E1.7650.65
31_L66_A1.7510.64
49_N99_G1.6980.62
8_M52_K1.6930.61
51_L83_F1.6910.61
16_F92_A1.6550.60
21_V96_A1.6100.57
6_G99_G1.5980.57
29_G47_L1.5520.54
21_V37_G1.5480.54
51_L57_V1.5380.54
105_W108_Q1.5290.53
67_V75_L1.5190.53
17_I21_V1.5180.53
89_I97_Q1.5160.53
9_V82_I1.5050.52
18_A39_P1.4740.51
12_I36_A1.4480.49
11_F87_L1.4280.48
63_T84_K1.4250.48
77_G96_A1.4250.48
42_T46_K1.4140.48
23_I102_I1.3980.47
29_G105_W1.3690.45
6_G9_V1.3380.44
11_F91_S1.3310.43
26_A48_A1.3090.42
7_F23_I1.2830.41
15_Y107_T1.2830.41
32_G56_L1.2710.40
55_A58_A1.2660.40
63_T89_I1.2340.39
70_F93_M1.2110.38
12_I58_A1.2100.38
52_K96_A1.2000.37
46_K98_S1.2000.37
83_F87_L1.1910.37
23_I76_E1.1780.36
29_G108_Q1.1650.35
26_A76_E1.1490.35
51_L65_D1.1410.34
98_S106_L1.1330.34
87_L103_I1.1280.34
72_R81_D1.1130.33
18_A35_L1.0860.32
74_I81_D1.0770.32
32_G51_L1.0710.31
37_G64_F1.0690.31
46_K63_T1.0460.30
9_V104_S1.0100.29
33_A52_K1.0100.29
39_P76_E1.0090.29
29_G84_K1.0080.29
8_M80_R1.0040.28
32_G99_G1.0000.28
64_F73_G0.9930.28
50_R74_I0.9630.27
7_F19_L0.9630.27
49_N90_I0.9410.26
82_I86_L0.9270.25
32_G48_A0.9100.25
14_S30_G0.9060.25
34_Y63_T0.9040.25
38_E84_K0.8960.24
41_L45_T0.8380.22
31_L38_E0.8290.22
75_L97_Q0.8130.21
92_A98_S0.8040.21
58_A66_A0.8040.21
6_G38_E0.7970.21
71_E77_G0.7930.21
35_L74_I0.7800.20
21_V58_A0.7720.20
16_F23_I0.7510.19
21_V77_G0.7480.19
28_I102_I0.7430.19
80_R100_W0.7370.19
30_G96_A0.7370.19
30_G44_I0.7340.19
21_V103_I0.7320.19
25_G65_D0.7230.18
9_V91_S0.7150.18
68_Y74_I0.7130.18
53_I65_D0.7090.18
27_L40_P0.7080.18
28_I90_I0.7060.18
33_A38_E0.6930.18
46_K52_K0.6920.18
10_N48_A0.6890.17
18_A57_V0.6880.17
30_G33_A0.6830.17
51_L58_A0.6780.17
21_V55_A0.6640.17
53_I105_W0.6600.17
10_N60_I0.6590.17
14_S67_V0.6590.17
48_A85_Q0.6480.16
34_Y69_S0.6460.16
52_K100_W0.6450.16
49_N76_E0.6440.16
74_I103_I0.6430.16
53_I89_I0.6430.16
35_L57_V0.6420.16
30_G100_W0.6370.16
34_Y107_T0.6270.16
6_G33_A0.6190.16
60_I91_S0.6180.15
79_T93_M0.6100.15
73_G84_K0.6020.15
8_M86_L0.6010.15
46_K75_L0.5980.15
7_F88_L0.5950.15
84_K89_I0.5910.15
26_A97_Q0.5890.15
19_L106_L0.5780.14
47_L67_V0.5780.14
66_A86_L0.5780.14
6_G10_N0.5780.14
15_Y22_L0.5750.14
40_P43_A0.5730.14
57_V67_V0.5720.14
41_L64_F0.5680.14
31_L74_I0.5680.14
39_P56_L0.5650.14
34_Y105_W0.5620.14
47_L91_S0.5590.14
22_L86_L0.5570.14
44_I52_K0.5490.14
6_G78_N0.5440.14
35_L39_P0.5400.14
10_N78_N0.5340.13
15_Y81_D0.5340.13
37_G94_G0.5330.13
17_I79_T0.5310.13
7_F18_A0.5210.13
11_F19_L0.5200.13
32_G82_I0.5180.13
9_V23_I0.5180.13
35_L52_K0.5170.13
60_I81_D0.5170.13
18_A58_A0.5110.13
19_L28_I0.5070.13
51_L84_K0.5040.13
36_A56_L0.5010.13
67_V104_S0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3llqA 3 0.8673 25.4 0.934 Contact Map
1ldfA 3 0.8142 24.9 0.934 Contact Map
2f2bA 4 0.8584 16.9 0.939 Contact Map
3c02A 3 0.9204 15.1 0.94 Contact Map
1j4nA 4 0.885 14.3 0.941 Contact Map
3zojA 3 0.885 11.5 0.944 Contact Map
3d9sA 3 0.8319 10.2 0.945 Contact Map
2o9gA 3 0.8673 9.7 0.945 Contact Map
4nefA 4 0.8938 8.3 0.947 Contact Map
2b6oA 6 0.8938 7 0.949 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0052 seconds.